Homo sapiens

18 known processes

OTUD4

OTU domain containing 4

(Aliases: HIN1,KIAA1046,DUBA6,DKFZp434I0721,HSHIN1)

OTUD4 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
cellular macromolecule catabolic processGO:00442653800.157
multicellular organismal agingGO:001025930.117
negative regulation of protein metabolic processGO:00512483910.109
post embryonic developmentGO:000979120.098
determination of adult lifespanGO:000834020.094
cell developmentGO:00484683280.092
positive regulation of developmental processGO:00510943140.085
negative regulation of cellular protein metabolic processGO:00322693530.080
negative regulation of apoptotic processGO:00430663160.075
cellular protein catabolic processGO:00442572610.075
modification dependent macromolecule catabolic processGO:00436322120.069
cell projection organizationGO:00300302520.067
negative regulation of programmed cell deathGO:00430693210.067
proteasomal protein catabolic processGO:00104981760.064
protein modification by small protein conjugationGO:00324463420.061
cytoplasmic transportGO:00164823790.055
protein ubiquitinationGO:00165673140.053
protein catabolic processGO:00301633250.052
cellular amine metabolic processGO:0044106410.052
actin cytoskeleton organizationGO:00300362070.051
rna processingGO:00063962550.051
cellular component morphogenesisGO:00329893140.051
growthGO:00400072020.050
positive regulation of cellular component organizationGO:00511303760.049
regulation of cellular component biogenesisGO:00440872810.048
amine metabolic processGO:0009308440.047
female gamete generationGO:000729220.045
posttranscriptional regulation of gene expressionGO:00106082130.045
regulation of apoptotic signaling pathwayGO:20012331750.044
anatomical structure formation involved in morphogenesisGO:00486462840.041
regulation of cellular response to stressGO:00801352440.040
modification dependent protein catabolic processGO:00199412090.040
negative regulation of cell deathGO:00605483450.039
response to abiotic stimulusGO:00096283360.038
nervous system developmentGO:00073992930.038
ribonucleoside triphosphate catabolic processGO:00092033910.037
cellular ketone metabolic processGO:0042180800.037
apoptotic signaling pathwayGO:00971902680.036
proteasome mediated ubiquitin dependent protein catabolic processGO:00431611560.036
regulation of cell differentiationGO:00455953930.036
organelle assemblyGO:00709251760.036
proteolysis involved in cellular protein catabolic processGO:00516032440.036
segmentationGO:003528240.035
cellular component assembly involved in morphogenesisGO:0010927730.035
cellular response to nitrogen compoundGO:19016991440.034
translationGO:00064121320.033
regulation of cell developmentGO:00602841610.033
oogenesisGO:004847720.032
protein processingGO:00164852260.031
cellular response to dna damage stimulusGO:00069743790.031
regulation of cellular ketone metabolic processGO:0010565500.031
nucleoside phosphate catabolic processGO:19012924120.030
nucleoside triphosphate metabolic processGO:00091414220.030
positive regulation of catabolic processGO:00098963100.030
cellular amino acid metabolic processGO:00065201160.030
negative regulation of multicellular organismal processGO:00512413170.030
negative regulation of intracellular signal transductionGO:19025321830.029
intrinsic apoptotic signaling pathwayGO:00971931270.029
cellular macromolecular complex assemblyGO:00346223240.029
cell morphogenesisGO:00009022960.029
regulation of cellular amine metabolic processGO:0033238110.029
regulation of intrinsic apoptotic signaling pathwayGO:2001242720.029
actin filament based processGO:00300292240.029
nucleoside catabolic processGO:00091644080.029
mitotic cell cycleGO:00002783260.029
protein localization to organelleGO:00333652800.029
negative regulation of cellular amino acid metabolic processGO:004576320.028
ubiquitin dependent protein catabolic processGO:00065112060.028
positive regulation of immune system processGO:00026842830.028
single organism cellular localizationGO:19025803320.027
response to biotic stimulusGO:00096072760.027
Human
purine nucleotide catabolic processGO:00061954050.027
organophosphate catabolic processGO:00464344300.027
blastoderm segmentationGO:000735020.027
ribonucleotide catabolic processGO:00092614050.027
nucleotide catabolic processGO:00091664080.027
positive regulation of cell proliferationGO:00082843010.027
purine ribonucleoside triphosphate metabolic processGO:00092054110.027
spermatid differentiationGO:004851540.026
response to organic cyclic compoundGO:00140702040.026
positive regulation of cellular amino acid metabolic processGO:004576430.026
positive regulation of cellular amine metabolic processGO:003324070.026
ribonucleoside triphosphate metabolic processGO:00091994120.026
purine ribonucleoside catabolic processGO:00461303980.026
defense responseGO:00069523150.026
regenerationGO:003109940.026
nucleoside triphosphate catabolic processGO:00091433940.026
single organism membrane organizationGO:00448022680.026
regulation of growthGO:00400081650.026
purine ribonucleoside metabolic processGO:00461284370.025
spermatid developmentGO:000728640.025
neuromuscular junction developmentGO:000752830.025
purine nucleoside triphosphate metabolic processGO:00091444120.025
regulation of protein processingGO:00706131500.025
activation of immune responseGO:00022531140.025
regulation of cytokine productionGO:00018172320.025
negative regulation of protein maturationGO:19033181420.025
protein maturationGO:00516042330.025
negative regulation of cellular amine metabolic processGO:003323930.025
mrna processingGO:00063971330.025
response to oxygen containing compoundGO:19017003690.025
Human
peripheral nervous system developmentGO:000742220.024
negative regulation of proteolysisGO:00458611320.024
mrna metabolic processGO:00160711750.024
negative regulation of transcription from rna polymerase ii promoterGO:00001222810.024
atp catabolic processGO:00062001570.024
response to external biotic stimulusGO:00432072610.024
Human
positive regulation of phosphorylationGO:00423273940.024
negative regulation of protein processingGO:00109551420.024
glycosyl compound catabolic processGO:19016584130.023
immune responseGO:00069553070.023
regulation of nucleotide metabolic processGO:00061402690.023
innate immune responseGO:00450871780.023
myosin filament assemblyGO:003103420.023
memoryGO:000761330.023
regulation of protein localizationGO:00328802960.023
neuron differentiationGO:00301821380.022
regulation of cellular amino acid metabolic processGO:000652160.022
reproductive processGO:00224141060.022
purine nucleoside monophosphate metabolic processGO:00091261860.022
chromatin modificationGO:00165682980.022
cellular response to endogenous stimulusGO:00714953360.022
cellular protein complex assemblyGO:00436231880.022
generation of neuronsGO:00486991520.022
protein targetingGO:00066051870.022
negative regulation of cell proliferationGO:00082852280.021
regulation of purine nucleotide catabolic processGO:00331212050.021
microtubule based processGO:00070172100.021
neuron developmentGO:00486661130.021
myosin filament organizationGO:003103320.021
positive regulation of cell developmentGO:0010720920.021
purine nucleoside triphosphate catabolic processGO:00091463920.021
regulation of cell migrationGO:00303342890.021
positive regulation of organelle organizationGO:00106381950.021
microtubule cytoskeleton organizationGO:00002261760.021
locomotory behaviorGO:000762610.021
regulation of translationGO:0006417890.021
response to nitrogen compoundGO:19016981840.021
regulation of cellular response to oxidative stressGO:1900407260.021
regulation of protein ubiquitinationGO:0031396950.021
positive regulation of immune responseGO:00507781590.021
positive regulation of nucleoside metabolic processGO:00459791860.021
regulation of proteasomal protein catabolic processGO:0061136870.021
striated muscle myosin thick filament assemblyGO:007168820.020
regulation of cell projection organizationGO:00313441070.020
cell part morphogenesisGO:00329901370.020
negative regulation of catalytic activityGO:00430863350.020
regulation of purine nucleotide metabolic processGO:19005422640.020
purine nucleoside catabolic processGO:00061523980.020
oocyte developmentGO:004859910.020
signal transduction by phosphorylationGO:00230142970.020
neurotransmitter secretionGO:000726940.020
positive regulation of cell differentiationGO:00455972110.020
regulation of protein catabolic processGO:00421761550.020
purine ribonucleotide catabolic processGO:00091544040.020
reactive nitrogen species metabolic processGO:200105730.020
regulation of anatomical structure morphogenesisGO:00226032860.020
membrane organizationGO:00610242920.020
establishment of protein localization to organelleGO:00725941720.020
interspecies interaction between organismsGO:00444191560.020
positive regulation of nucleotide catabolic processGO:00308131850.019
negative regulation of apoptotic signaling pathwayGO:2001234970.019
regulation of protein maturationGO:19033171500.019
cell projection morphogenesisGO:00488581290.019
regulation of cell motilityGO:20001452990.019
regulation of cellular component movementGO:00512703340.019
intracellular protein transportGO:00068862700.019
purine containing compound catabolic processGO:00725234110.019
purine ribonucleoside triphosphate catabolic processGO:00092073910.019
wnt signaling pathwayGO:00160551560.019
muscle structure developmentGO:0061061980.019
reactive oxygen species biosynthetic processGO:190340940.018
cellular response to organic cyclic compoundGO:00714071270.018
ribonucleoside catabolic processGO:00424544060.018
nuclear transportGO:00511691790.018
regulation of cellular protein catabolic processGO:1903362960.018
regulation of secretion by cellGO:19035301770.018
negative regulation of catabolic processGO:00098951040.018
ras protein signal transductionGO:0007265730.018
neurogenesisGO:00220081690.018
epithelial cell differentiationGO:00308551410.018
vesicle mediated transportGO:00161923710.018
viral processGO:00160321460.018
positive regulation of cellular catabolic processGO:00313312840.018
cellular lipid metabolic processGO:00442553030.018
regulation of nucleotide catabolic processGO:00308112050.018
regulation of cell cycleGO:00517263930.018
nucleic acid phosphodiester bond hydrolysisGO:00903051020.018
regulation of neurogenesisGO:0050767820.018
limbic system developmentGO:002176130.018
rna interferenceGO:001624640.017
response to fungusGO:000962040.017
symbiosis encompassing mutualism through parasitismGO:00444031560.017
positive regulation of hydrolase activityGO:00513453310.017
regulation of proteasomal ubiquitin dependent protein catabolic processGO:0032434710.017
positive regulation of protein phosphorylationGO:00019343130.017
nucleoside monophosphate catabolic processGO:00091251590.017
biological adhesionGO:00226103310.017
chromatin organizationGO:00063253510.017
regulation of bindingGO:00510981110.017
agingGO:0007568660.017
atp metabolic processGO:00460341760.017
inorganic ion transmembrane transportGO:00986602310.017
rho protein signal transductionGO:0007266260.017
multi organism cellular processGO:00447641560.017
dephosphorylationGO:00163112090.017
positive regulation of transferase activityGO:00513472270.017
regulation of nucleoside metabolic processGO:00091182090.017
negative regulation of developmental processGO:00510932470.017
nerve developmentGO:002167540.016
transmembrane transportGO:00550853990.016
regulation of cell morphogenesisGO:00226041530.016
regulation of protein transportGO:00512232130.016
ion homeostasisGO:00508012300.016
ion transmembrane transportGO:00342203380.016
cell fate determinationGO:000170930.016
regulation of response to external stimulusGO:00321012220.016
regulation of immune responseGO:00507762010.016
covalent chromatin modificationGO:00165692540.016
negative regulation of protein modification processGO:00314002000.016
positive regulation of transportGO:00510503360.016
glial cell migrationGO:000834740.016
regulation of proteolysisGO:00301622930.016
reactive oxygen species metabolic processGO:0072593750.016
regulation of gene expression epigeneticGO:0040029730.016
small gtpase mediated signal transductionGO:0007264780.016
rhythmic behaviorGO:000762220.016
ribonucleoside monophosphate metabolic processGO:00091611870.016
cell activationGO:00017752130.016
epithelium developmentGO:00604292270.016
nucleocytoplasmic transportGO:00069131760.015
associative learningGO:000830610.015
epidermis morphogenesisGO:004873030.015
regulation of neurotransmitter secretionGO:004692830.015
nitrogen compound transportGO:00717051910.015
lipid metabolic processGO:00066293810.015
cellular response to nutrient levelsGO:0031669690.015
regulation of proteolysis involved in cellular protein catabolic processGO:1903050910.015
metal ion transportGO:00300012720.015
compound eye developmentGO:004874910.015
cell growthGO:00160491600.015
blood vessel morphogenesisGO:00485141620.015
regulation of cytoskeleton organizationGO:00514931770.015
carbohydrate metabolic processGO:00059752070.015
oocyte differentiationGO:000999420.015
translational initiationGO:0006413480.015
negative regulation of phosphorus metabolic processGO:00105632670.015
purine ribonucleoside monophosphate metabolic processGO:00091671860.015
rna catabolic processGO:0006401710.015
muscle cell differentiationGO:0042692630.015
cell projection assemblyGO:00300311260.015
negative regulation of organelle organizationGO:00106391260.015
regulation of establishment of protein localizationGO:00702012420.015
regulation of oxidative stress induced cell deathGO:1903201240.015
neuroblast proliferationGO:000740540.015
cation transmembrane transportGO:00986552380.015
rna splicingGO:00083801310.015
positive regulation of nucleotide metabolic processGO:00459812300.015
secretion by cellGO:00329402260.015
cell cycle phase transitionGO:00447701730.015
positive regulation of programmed cell deathGO:00430682490.014
organonitrogen compound biosynthetic processGO:19015662000.014
neuron projection developmentGO:00311751060.014
negative regulation of hydrolase activityGO:00513461820.014
regulation of kinase activityGO:00435493140.014
regulation of cell growthGO:00015581350.014
cell death in response to oxidative stressGO:0036473290.014
histone modificationGO:00165702510.014
positive regulation of purine nucleotide catabolic processGO:00331231850.014
cellular ion homeostasisGO:00068731680.014
extrinsic apoptotic signaling pathwayGO:00971911190.014
positive regulation of kinase activityGO:00336742040.014
dna repairGO:00062811980.014
regulation of intracellular transportGO:00323861950.014
response to cytokineGO:00340972320.014
tissue regenerationGO:004224630.014
cell adhesionGO:00071553250.014
anterior posterior axis specificationGO:000994820.014
immune response activating signal transductionGO:0002757900.014
negative regulation of cellular catabolic processGO:0031330830.014
protein targeting to nucleusGO:00447441040.014
cytokine productionGO:00018162470.014
motor neuron axon guidanceGO:000804520.014
maintenance of locationGO:00512351120.013
intrinsic apoptotic signaling pathway in response to oxidative stressGO:0008631210.013
regulation of transferase activityGO:00513383550.013
regulation of reactive oxygen species biosynthetic processGO:190342630.013
regulation of i kappab kinase nf kappab signalingGO:00431221620.013
regulation of ras protein signal transductionGO:00465781550.013
cellular response to abiotic stimulusGO:00712141170.013
regulation of neuron differentiationGO:0045664700.013
adult locomotory behaviorGO:000834410.013
negative regulation of cellular component organizationGO:00511292350.013
guanosine containing compound catabolic processGO:19010692390.013
organelle fissionGO:00482851490.013
embryo developmentGO:00097901230.013
hemopoiesisGO:00300971800.013
cellular response to oxygen containing compoundGO:19017012760.013
actomyosin structure organizationGO:0031032590.013
taxisGO:00423301570.013
protein polyubiquitinationGO:00002091100.013
histone acetylationGO:0016573930.013
positive regulation of purine nucleotide metabolic processGO:19005442270.013
immune response regulating signaling pathwayGO:0002764970.013
cellular response to extracellular stimulusGO:0031668720.013
cilium assemblyGO:0042384630.012
mitotic cell cycle processGO:19030472860.012
nucleoside monophosphate metabolic processGO:00091231910.012
regulation of secretionGO:00510461940.012
positive regulation of growthGO:0045927580.012
embryonic hindlimb morphogenesisGO:003511620.012
immune effector processGO:00022521590.012
positive regulation of gtp catabolic processGO:00331261660.012
regulation of cell cycle processGO:00105642660.012
dna conformation changeGO:00711031130.012
response to organonitrogen compoundGO:00102431560.012
regulation of cell divisionGO:00513021160.012
regulation of cytoplasmic transportGO:19036491490.012
organ morphogenesisGO:00098871470.012
hindlimb morphogenesisGO:003513720.012
anatomical structure homeostasisGO:00602491000.012
sequestering of metal ionGO:0051238240.012
mrna catabolic processGO:0006402560.012
regulation of chromosome organizationGO:00330441030.012
ribonucleoside monophosphate catabolic processGO:00091581580.012
regulation of wnt signaling pathwayGO:00301111230.012
chemotaxisGO:00069351570.012
regulation of response to dna damage stimulusGO:2001020940.012
regulation of nervous system developmentGO:0051960880.012
inner ear morphogenesisGO:004247240.012
mitotic cell cycle phase transitionGO:00447721620.012
purine nucleoside monophosphate catabolic processGO:00091281580.012
cellular homeostasisGO:00197251960.012
golgi vesicle transportGO:0048193800.012
negative regulation of translationGO:0017148370.012
mitotic nuclear divisionGO:00070671190.012
cardiac muscle cell contractionGO:008600340.012
positive regulation of cytokine productionGO:00018191670.012
mapk cascadeGO:00001652880.012
negative regulation of cell cycleGO:00457861930.012
regulation of defense responseGO:00313471540.012
positive regulation of apoptotic processGO:00430652460.011
divalent inorganic cation homeostasisGO:00725071360.011
regulation of neuron projection developmentGO:0010975570.011
negative regulation of cellular response to oxidative stressGO:1900408180.011
single organism carbohydrate metabolic processGO:00447231930.011
defense response to fungusGO:005083240.011
long term memoryGO:000761620.011
response to axon injuryGO:004867810.011
response to hormoneGO:00097251750.011
actin mediated cell contractionGO:0070252120.011
regulation of oxidative stress induced intrinsic apoptotic signaling pathwayGO:1902175160.011
regulation of multi organism processGO:00439001570.011
neurological system processGO:00508771630.011
protein localization to membraneGO:00726571600.011
hair follicle morphogenesisGO:003106920.011
regulation of neural precursor cell proliferationGO:200017740.011
anterior posterior axis specification embryoGO:000859520.011
regulation of sequence specific dna binding transcription factor activityGO:00510902110.011
divalent inorganic cation transportGO:00725111580.011
negative regulation of cell migrationGO:00303361020.011
morphogenesis of embryonic epitheliumGO:001633140.011
regulation of homeostatic processGO:00328441210.011
meiotic chromosome segregationGO:004513240.011
cell type specific apoptotic processGO:00972851250.011
regulation of synaptic plasticityGO:004816730.011
response to other organismGO:00517072610.011
Human
regulation of response to oxidative stressGO:1902882260.011
response to extracellular stimulusGO:0009991850.011
regulation of peptidase activityGO:00525471800.011
cellular response to external stimulusGO:00714961110.011
cilium morphogenesisGO:0060271750.011
gtp metabolic processGO:00460392390.011
dna replicationGO:00062601160.011
negative regulation of proteasomal protein catabolic processGO:1901799320.011
peptidyl tyrosine phosphorylationGO:00181081700.011
viral life cycleGO:00190581320.011
negative regulation of intrinsic apoptotic signaling pathwayGO:2001243400.011
positive regulation of protein kinase activityGO:00458601900.011
regulation of mapk cascadeGO:00434082620.011
synaptic vesicle exocytosisGO:001607930.011
thymus developmentGO:004853830.011
tripartite regional subdivisionGO:000735120.010
cellular response to starvationGO:0009267580.010
cellular response to cytokine stimulusGO:00713451810.010
blood vessel developmentGO:00015681720.010
photoreceptor cell differentiationGO:004653020.010
myeloid leukocyte differentiationGO:0002573600.010
protein importGO:00170381300.010
protein localization to nucleusGO:00345041360.010
regulation of mrna processingGO:0050684480.010
myeloid cell differentiationGO:00300991170.010
embryonic epithelial tube formationGO:000183840.010
negative regulation of protein catabolic processGO:0042177590.010
cellular amide metabolic processGO:0043603690.010
peptidyl serine phosphorylationGO:00181051010.010
positive regulation of innate immune responseGO:0045089790.010
striated muscle contractionGO:0006941520.010
syncytium formation by plasma membrane fusionGO:000076820.010
cellular calcium ion homeostasisGO:00068741170.010
positive regulation of cell cycle processGO:00900681060.010
cell divisionGO:00513011680.010
muscle contractionGO:0006936730.010
regulation of reactive oxygen species metabolic processGO:2000377410.010
actin filament based movementGO:0030048170.010
negative regulation of phosphate metabolic processGO:00459362670.010
regulation of symbiosis encompassing mutualism through parasitismGO:00439031090.010
negative regulation of response to oxidative stressGO:1902883180.010

OTUD4 disease predictions

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of cellular proliferationDOID:145661740.026
cancerDOID:1621670.017
organ system cancerDOID:00506861640.016
disease of metabolismDOID:00146672950.015
nervous system diseaseDOID:8634310.015
sensory system diseaseDOID:00501552030.015
musculoskeletal system diseaseDOID:172230.013
central nervous system diseaseDOID:3311860.013
eye and adnexa diseaseDOID:14921500.012
eye diseaseDOID:56141490.012
inherited metabolic disorderDOID:6552420.011