| protein catabolic process | GO:0030163 | 325 | 0.170 | |
| protein modification by small protein conjugation | GO:0032446 | 342 | 0.165 | |
| proteolysis involved in cellular protein catabolic process | GO:0051603 | 244 | 0.132 | |
| protein ubiquitination | GO:0016567 | 314 | 0.128 | |
| negative regulation of cell death | GO:0060548 | 345 | 0.124 | Rat |
| positive regulation of apoptotic process | GO:0043065 | 246 | 0.116 | |
| negative regulation of programmed cell death | GO:0043069 | 321 | 0.115 | |
| positive regulation of cell death | GO:0010942 | 263 | 0.109 | |
| negative regulation of cellular protein metabolic process | GO:0032269 | 353 | 0.107 | |
| negative regulation of protein metabolic process | GO:0051248 | 391 | 0.098 | |
| cellular response to dna damage stimulus | GO:0006974 | 379 | 0.096 | |
| negative regulation of intracellular signal transduction | GO:1902532 | 183 | 0.094 | |
| modification dependent protein catabolic process | GO:0019941 | 209 | 0.092 | |
| negative regulation of apoptotic process | GO:0043066 | 316 | 0.091 | |
| cellular protein catabolic process | GO:0044257 | 261 | 0.088 | |
| protein processing | GO:0016485 | 226 | 0.083 | |
| protein maturation | GO:0051604 | 233 | 0.080 | |
| negative regulation of proteolysis | GO:0045861 | 132 | 0.078 | |
| cellular amino acid metabolic process | GO:0006520 | 116 | 0.075 | |
| response to abiotic stimulus | GO:0009628 | 336 | 0.075 | |
| negative regulation of protein maturation | GO:1903318 | 142 | 0.072 | |
| regulation of protein maturation | GO:1903317 | 150 | 0.071 | |
| negative regulation of protein processing | GO:0010955 | 142 | 0.071 | |
| regulation of cell differentiation | GO:0045595 | 393 | 0.063 | |
| positive regulation of cellular amine metabolic process | GO:0033240 | 7 | 0.062 | |
| positive regulation of programmed cell death | GO:0043068 | 249 | 0.059 | |
| regulation of proteolysis | GO:0030162 | 293 | 0.058 | |
| negative regulation of developmental process | GO:0051093 | 247 | 0.058 | |
| negative regulation of catalytic activity | GO:0043086 | 335 | 0.057 | |
| regulation of cellular amine metabolic process | GO:0033238 | 11 | 0.055 | |
| positive regulation of cellular amino acid metabolic process | GO:0045764 | 3 | 0.055 | |
| regulation of cellular ketone metabolic process | GO:0010565 | 50 | 0.049 | |
| small gtpase mediated signal transduction | GO:0007264 | 78 | 0.049 | |
| regulation of cellular response to stress | GO:0080135 | 244 | 0.049 | |
| regulation of transferase activity | GO:0051338 | 355 | 0.048 | |
| cellular amine metabolic process | GO:0044106 | 41 | 0.047 | |
| response to oxygen containing compound | GO:1901700 | 369 | 0.047 | |
| positive regulation of transferase activity | GO:0051347 | 227 | 0.047 | |
| ubiquitin dependent protein catabolic process | GO:0006511 | 206 | 0.044 | |
| response to cytokine | GO:0034097 | 232 | 0.044 | |
| response to light stimulus | GO:0009416 | 87 | 0.044 | |
| positive regulation of response to dna damage stimulus | GO:2001022 | 43 | 0.042 | |
| response to radiation | GO:0009314 | 151 | 0.042 | |
| amine metabolic process | GO:0009308 | 44 | 0.042 | |
| negative regulation of apoptotic signaling pathway | GO:2001234 | 97 | 0.040 | |
| positive regulation of developmental process | GO:0051094 | 314 | 0.040 | |
| cellular response to cytokine stimulus | GO:0071345 | 181 | 0.037 | |
| regulation of protein catabolic process | GO:0042176 | 155 | 0.037 | |
| i kappab kinase nf kappab signaling | GO:0007249 | 166 | 0.037 | |
| regulation of i kappab kinase nf kappab signaling | GO:0043122 | 162 | 0.037 | |
| regulation of protein processing | GO:0070613 | 150 | 0.036 | |
| positive regulation of cell differentiation | GO:0045597 | 211 | 0.036 | |
| regulation of cellular amino acid metabolic process | GO:0006521 | 6 | 0.035 | |
| regulation of cell cycle process | GO:0010564 | 266 | 0.034 | |
| dna repair | GO:0006281 | 198 | 0.034 | |
| positive regulation of i kappab kinase nf kappab signaling | GO:0043123 | 132 | 0.033 | |
| regulation of dna metabolic process | GO:0051052 | 153 | 0.032 | |
| cellular ketone metabolic process | GO:0042180 | 80 | 0.032 | |
| cellular response to endogenous stimulus | GO:0071495 | 336 | 0.032 | |
| apoptotic signaling pathway | GO:0097190 | 268 | 0.031 | |
| immune response | GO:0006955 | 307 | 0.031 | |
| post embryonic development | GO:0009791 | 2 | 0.030 | |
| regulation of proteolysis involved in cellular protein catabolic process | GO:1903050 | 91 | 0.030 | |
| protein oligomerization | GO:0051259 | 173 | 0.029 | |
| modification dependent macromolecule catabolic process | GO:0043632 | 212 | 0.029 | |
| system process | GO:0003008 | 349 | 0.028 | |
| locomotory behavior | GO:0007626 | 1 | 0.028 | Mouse |
| protein homooligomerization | GO:0051260 | 100 | 0.028 | |
| regulation of intrinsic apoptotic signaling pathway | GO:2001242 | 72 | 0.027 | |
| positive regulation of immune system process | GO:0002684 | 283 | 0.027 | |
| establishment of protein localization to organelle | GO:0072594 | 172 | 0.027 | |
| positive regulation of protein phosphorylation | GO:0001934 | 313 | 0.027 | |
| defense response | GO:0006952 | 315 | 0.027 | |
| multicellular organismal aging | GO:0010259 | 3 | 0.027 | |
| regulation of cysteine type endopeptidase activity | GO:2000116 | 127 | 0.027 | |
| pharynx development | GO:0060465 | 1 | 0.026 | |
| cell cycle arrest | GO:0007050 | 71 | 0.026 | |
| cellular response to lipid | GO:0071396 | 127 | 0.025 | |
| hemopoiesis | GO:0030097 | 180 | 0.025 | |
| regulation of cellular protein catabolic process | GO:1903362 | 96 | 0.025 | |
| epithelium development | GO:0060429 | 227 | 0.025 | |
| response to uv | GO:0009411 | 73 | 0.025 | |
| ras protein signal transduction | GO:0007265 | 73 | 0.024 | |
| proteasomal protein catabolic process | GO:0010498 | 176 | 0.024 | |
| oogenesis | GO:0048477 | 2 | 0.024 | |
| dna demethylation | GO:0080111 | 12 | 0.023 | |
| coenzyme metabolic process | GO:0006732 | 65 | 0.023 | |
| positive regulation of cell cycle process | GO:0090068 | 106 | 0.023 | |
| monocarboxylic acid metabolic process | GO:0032787 | 185 | 0.023 | |
| negative regulation of transcription from rna polymerase ii promoter | GO:0000122 | 281 | 0.023 | |
| regulation of protein ubiquitination | GO:0031396 | 95 | 0.023 | |
| oocyte development | GO:0048599 | 1 | 0.023 | |
| nervous system development | GO:0007399 | 293 | 0.022 | Mouse |
| response to biotic stimulus | GO:0009607 | 276 | 0.022 | |
| regulation of symbiosis encompassing mutualism through parasitism | GO:0043903 | 109 | 0.022 | |
| regulation of peptidase activity | GO:0052547 | 180 | 0.022 | |
| regulation of response to dna damage stimulus | GO:2001020 | 94 | 0.022 | |
| positive regulation of apoptotic signaling pathway | GO:2001235 | 70 | 0.022 | |
| cell division | GO:0051301 | 168 | 0.022 | |
| cellular macromolecule catabolic process | GO:0044265 | 380 | 0.022 | |
| negative regulation of cellular catabolic process | GO:0031330 | 83 | 0.022 | |
| protein acetylation | GO:0006473 | 116 | 0.022 | |
| chromatin modification | GO:0016568 | 298 | 0.022 | |
| negative regulation of catabolic process | GO:0009895 | 104 | 0.022 | |
| intracellular protein transport | GO:0006886 | 270 | 0.021 | |
| positive regulation of cell cycle | GO:0045787 | 140 | 0.021 | |
| positive regulation of protein ubiquitination | GO:0031398 | 53 | 0.021 | |
| regulation of leukocyte activation | GO:0002694 | 115 | 0.021 | |
| cellular response to growth factor stimulus | GO:0071363 | 197 | 0.021 | |
| extrinsic apoptotic signaling pathway | GO:0097191 | 119 | 0.021 | |
| positive regulation of hydrolase activity | GO:0051345 | 331 | 0.021 | |
| cellular lipid metabolic process | GO:0044255 | 303 | 0.021 | Rat |
| growth | GO:0040007 | 202 | 0.021 | Mouse |
| immune effector process | GO:0002252 | 159 | 0.020 | |
| intrinsic apoptotic signaling pathway | GO:0097193 | 127 | 0.020 | |
| cell growth | GO:0016049 | 160 | 0.020 | |
| regulation of cell cycle | GO:0051726 | 393 | 0.020 | |
| negative regulation of protein modification process | GO:0031400 | 200 | 0.020 | |
| proteasome mediated ubiquitin dependent protein catabolic process | GO:0043161 | 156 | 0.020 | |
| regulation of leukocyte differentiation | GO:1902105 | 61 | 0.020 | |
| neurogenesis | GO:0022008 | 169 | 0.020 | Mouse |
| protein polyubiquitination | GO:0000209 | 110 | 0.020 | |
| demethylation | GO:0070988 | 37 | 0.020 | |
| regulation of protein kinase activity | GO:0045859 | 289 | 0.020 | |
| protein acylation | GO:0043543 | 138 | 0.020 | |
| response to inorganic substance | GO:0010035 | 127 | 0.020 | |
| positive regulation of myeloid cell differentiation | GO:0045639 | 39 | 0.019 | |
| regulation of kinase activity | GO:0043549 | 314 | 0.019 | |
| protein localization to organelle | GO:0033365 | 280 | 0.019 | |
| determination of adult lifespan | GO:0008340 | 2 | 0.019 | |
| negative regulation of peptidase activity | GO:0010466 | 91 | 0.019 | |
| positive regulation of phosphorylation | GO:0042327 | 394 | 0.019 | |
| dephosphorylation | GO:0016311 | 209 | 0.018 | |
| regulation of transcription during mitosis | GO:0045896 | 2 | 0.018 | |
| purine ribonucleotide catabolic process | GO:0009154 | 404 | 0.018 | |
| transmembrane transport | GO:0055085 | 399 | 0.018 | |
| regulation of viral process | GO:0050792 | 103 | 0.018 | |
| methylation | GO:0032259 | 106 | 0.018 | |
| covalent chromatin modification | GO:0016569 | 254 | 0.018 | |
| actin mediated cell contraction | GO:0070252 | 12 | 0.018 | |
| ribonucleoside catabolic process | GO:0042454 | 406 | 0.018 | |
| secretion by cell | GO:0032940 | 226 | 0.018 | |
| sulfur compound metabolic process | GO:0006790 | 101 | 0.018 | |
| positive regulation of protein modification by small protein conjugation or removal | GO:1903322 | 61 | 0.017 | |
| negative regulation of cell cycle | GO:0045786 | 193 | 0.017 | |
| positive regulation of binding | GO:0051099 | 45 | 0.017 | |
| positive regulation of organelle organization | GO:0010638 | 195 | 0.017 | |
| positive regulation of cytokine production | GO:0001819 | 167 | 0.017 | |
| positive regulation of myeloid leukocyte differentiation | GO:0002763 | 24 | 0.017 | |
| female gamete generation | GO:0007292 | 2 | 0.017 | |
| neurological system process | GO:0050877 | 163 | 0.017 | |
| transmembrane receptor protein serine threonine kinase signaling pathway | GO:0007178 | 125 | 0.017 | |
| regulation of protein modification by small protein conjugation or removal | GO:1903320 | 107 | 0.017 | |
| cranial nerve development | GO:0021545 | 4 | 0.016 | |
| protein polymerization | GO:0051258 | 71 | 0.016 | |
| innate immune response | GO:0045087 | 178 | 0.016 | |
| cellular response to abiotic stimulus | GO:0071214 | 117 | 0.016 | |
| regulation of proteasomal ubiquitin dependent protein catabolic process | GO:0032434 | 71 | 0.016 | |
| urogenital system development | GO:0001655 | 65 | 0.016 | |
| posttranscriptional regulation of gene expression | GO:0010608 | 213 | 0.016 | |
| organophosphate catabolic process | GO:0046434 | 430 | 0.016 | |
| response to wounding | GO:0009611 | 168 | 0.016 | |
| response to metal ion | GO:0010038 | 84 | 0.016 | |
| regulation of apoptotic signaling pathway | GO:2001233 | 175 | 0.016 | |
| response to organic cyclic compound | GO:0014070 | 204 | 0.016 | |
| atp metabolic process | GO:0046034 | 176 | 0.016 | |
| cellular protein complex assembly | GO:0043623 | 188 | 0.016 | |
| protein autophosphorylation | GO:0046777 | 123 | 0.016 | |
| regulation of binding | GO:0051098 | 111 | 0.016 | |
| response to other organism | GO:0051707 | 261 | 0.016 | |
| histone modification | GO:0016570 | 251 | 0.016 | |
| negative regulation of cell differentiation | GO:0045596 | 171 | 0.016 | |
| regulation of protein serine threonine kinase activity | GO:0071900 | 179 | 0.015 | |
| cell cycle phase transition | GO:0044770 | 173 | 0.015 | |
| cell cycle checkpoint | GO:0000075 | 117 | 0.015 | |
| positive regulation of cysteine type endopeptidase activity involved in apoptotic process | GO:0043280 | 69 | 0.015 | |
| dna integrity checkpoint | GO:0031570 | 71 | 0.015 | |
| macromolecule methylation | GO:0043414 | 97 | 0.015 | |
| response to growth factor | GO:0070848 | 205 | 0.015 | |
| cofactor metabolic process | GO:0051186 | 87 | 0.015 | |
| peptidyl serine phosphorylation | GO:0018105 | 101 | 0.015 | |
| response to lipid | GO:0033993 | 206 | 0.015 | |
| negative regulation of hydrolase activity | GO:0051346 | 182 | 0.015 | |
| apoptotic mitochondrial changes | GO:0008637 | 57 | 0.015 | |
| cellular response to external stimulus | GO:0071496 | 111 | 0.015 | |
| regulation of proteasomal protein catabolic process | GO:0061136 | 87 | 0.015 | |
| response to nitric oxide | GO:0071731 | 4 | 0.015 | |
| peptidyl serine modification | GO:0018209 | 106 | 0.015 | |
| negative regulation of endopeptidase activity | GO:0010951 | 84 | 0.015 | |
| hematopoietic or lymphoid organ development | GO:0048534 | 186 | 0.014 | |
| positive regulation of leukocyte differentiation | GO:1902107 | 37 | 0.014 | |
| organelle fission | GO:0048285 | 149 | 0.014 | |
| response to virus | GO:0009615 | 126 | 0.014 | |
| regulation of protein transport | GO:0051223 | 213 | 0.014 | |
| positive regulation of kinase activity | GO:0033674 | 204 | 0.014 | |
| rho protein signal transduction | GO:0007266 | 26 | 0.014 | |
| nerve development | GO:0021675 | 4 | 0.014 | |
| maintenance of location | GO:0051235 | 112 | 0.014 | |
| dna replication | GO:0006260 | 116 | 0.014 | |
| regulation of establishment of protein localization | GO:0070201 | 242 | 0.014 | |
| nucleoside catabolic process | GO:0009164 | 408 | 0.014 | |
| cellular macromolecular complex assembly | GO:0034622 | 324 | 0.014 | |
| meiosis i | GO:0007127 | 4 | 0.013 | |
| enzyme linked receptor protein signaling pathway | GO:0007167 | 303 | 0.013 | |
| negative regulation of cell proliferation | GO:0008285 | 228 | 0.013 | |
| regulation of myeloid cell differentiation | GO:0045637 | 81 | 0.013 | |
| glycosyl compound catabolic process | GO:1901658 | 413 | 0.013 | |
| cytoplasmic transport | GO:0016482 | 379 | 0.013 | |
| cellular response to oxygen containing compound | GO:1901701 | 276 | 0.013 | |
| symbiosis encompassing mutualism through parasitism | GO:0044403 | 156 | 0.013 | |
| regulation of protein localization | GO:0032880 | 296 | 0.013 | |
| purine ribonucleoside triphosphate catabolic process | GO:0009207 | 391 | 0.013 | |
| dna damage checkpoint | GO:0000077 | 68 | 0.013 | |
| regulation of synaptic plasticity | GO:0048167 | 3 | 0.013 | |
| regulation of protein complex assembly | GO:0043254 | 147 | 0.013 | |
| protein import | GO:0017038 | 130 | 0.013 | |
| regulation of endopeptidase activity | GO:0052548 | 170 | 0.013 | |
| regulation of response to external stimulus | GO:0032101 | 222 | 0.013 | |
| chromatin organization | GO:0006325 | 351 | 0.013 | |
| ribonucleoside triphosphate catabolic process | GO:0009203 | 391 | 0.013 | |
| negative regulation of phosphorus metabolic process | GO:0010563 | 267 | 0.013 | |
| cell morphogenesis | GO:0000902 | 296 | 0.013 | |
| peptidyl tyrosine phosphorylation | GO:0018108 | 170 | 0.013 | |
| regulation of multi organism process | GO:0043900 | 157 | 0.013 | |
| ribonucleotide catabolic process | GO:0009261 | 405 | 0.013 | |
| regulation of immune response | GO:0050776 | 201 | 0.013 | |
| reactive oxygen species metabolic process | GO:0072593 | 75 | 0.013 | |
| cell aging | GO:0007569 | 52 | 0.012 | |
| hindbrain development | GO:0030902 | 3 | 0.012 | |
| response to external biotic stimulus | GO:0043207 | 261 | 0.012 | |
| negative regulation of protein catabolic process | GO:0042177 | 59 | 0.012 | |
| regulation of canonical wnt signaling pathway | GO:0060828 | 88 | 0.012 | |
| purine nucleoside triphosphate catabolic process | GO:0009146 | 392 | 0.012 | |
| single organism membrane organization | GO:0044802 | 268 | 0.012 | |
| rna splicing | GO:0008380 | 131 | 0.012 | |
| regulation of chromosome organization | GO:0033044 | 103 | 0.012 | |
| lipid metabolic process | GO:0006629 | 381 | 0.012 | Rat |
| secretion | GO:0046903 | 254 | 0.012 | |
| mitotic cell cycle | GO:0000278 | 326 | 0.012 | |
| peptidyl tyrosine modification | GO:0018212 | 170 | 0.012 | |
| regulation of secretion by cell | GO:1903530 | 177 | 0.012 | |
| myeloid cell differentiation | GO:0030099 | 117 | 0.012 | |
| positive regulation of transport | GO:0051050 | 336 | 0.012 | |
| anatomical structure homeostasis | GO:0060249 | 100 | 0.012 | |
| segmentation | GO:0035282 | 4 | 0.012 | |
| negative regulation of multi organism process | GO:0043901 | 92 | 0.012 | |
| nucleoside phosphate catabolic process | GO:1901292 | 412 | 0.012 | |
| purine nucleoside catabolic process | GO:0006152 | 398 | 0.012 | |
| fatty acid metabolic process | GO:0006631 | 115 | 0.012 | |
| purine containing compound catabolic process | GO:0072523 | 411 | 0.011 | |
| actin filament based movement | GO:0030048 | 17 | 0.011 | |
| cranial nerve morphogenesis | GO:0021602 | 1 | 0.011 | |
| purine ribonucleoside triphosphate metabolic process | GO:0009205 | 411 | 0.011 | |
| protein localization to nucleus | GO:0034504 | 136 | 0.011 | |
| viral process | GO:0016032 | 146 | 0.011 | |
| nucleoside monophosphate metabolic process | GO:0009123 | 191 | 0.011 | |
| immune system development | GO:0002520 | 195 | 0.011 | |
| positive regulation of dna metabolic process | GO:0051054 | 73 | 0.011 | |
| regulation of secretion | GO:0051046 | 194 | 0.011 | |
| negative regulation of dna metabolic process | GO:0051053 | 57 | 0.011 | |
| positive regulation of cysteine type endopeptidase activity | GO:2001056 | 79 | 0.011 | |
| interspecies interaction between organisms | GO:0044419 | 156 | 0.011 | |
| response to lipopolysaccharide | GO:0032496 | 70 | 0.011 | |
| regulation of transmembrane receptor protein serine threonine kinase signaling pathway | GO:0090092 | 90 | 0.011 | |
| regulation of cytoskeleton organization | GO:0051493 | 177 | 0.011 | |
| optic nerve development | GO:0021554 | 2 | 0.011 | |
| viral life cycle | GO:0019058 | 132 | 0.011 | |
| leukocyte differentiation | GO:0002521 | 98 | 0.011 | |
| compound eye development | GO:0048749 | 1 | 0.011 | |
| associative learning | GO:0008306 | 1 | 0.011 | |
| defense response to other organism | GO:0098542 | 129 | 0.011 | |
| negative regulation of intrinsic apoptotic signaling pathway | GO:2001243 | 40 | 0.011 | |
| multi organism cellular process | GO:0044764 | 156 | 0.011 | |
| positive regulation of catabolic process | GO:0009896 | 310 | 0.011 | |
| negative regulation of multicellular organismal process | GO:0051241 | 317 | 0.011 | |
| positive regulation of peptidyl tyrosine phosphorylation | GO:0050731 | 85 | 0.011 | |
| ion transmembrane transport | GO:0034220 | 338 | 0.011 | |
| endosomal transport | GO:0016197 | 129 | 0.010 | |
| regulation of cytoplasmic transport | GO:1903649 | 149 | 0.010 | |
| viral release from host cell | GO:0019076 | 21 | 0.010 | |
| axis elongation | GO:0003401 | 4 | 0.010 | |
| positive regulation of immune response | GO:0050778 | 159 | 0.010 | |
| regulation of ras protein signal transduction | GO:0046578 | 155 | 0.010 | |
| cell part morphogenesis | GO:0032990 | 137 | 0.010 | |
| negative regulation of cellular protein catabolic process | GO:1903363 | 38 | 0.010 | |
| cellular homeostasis | GO:0019725 | 196 | 0.010 | |
| positive regulation of cellular component biogenesis | GO:0044089 | 158 | 0.010 | |
| regulation of nucleotide metabolic process | GO:0006140 | 269 | 0.010 | |
| neuromuscular junction development | GO:0007528 | 3 | 0.010 | |
| single organismal cell cell adhesion | GO:0016337 | 148 | 0.010 | |
