Homo sapiens

7 known processes

ARHGEF6

Rac/Cdc42 guanine nucleotide exchange factor (GEF) 6

(Aliases: Cool-2,KIAA0006,COOL2,MRX46,alpha-PIX,PIXA,alphaPIX)

ARHGEF6 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
positive regulation of fibroblast migrationGO:001076330.250
Human
purine ribonucleoside triphosphate catabolic processGO:00092073910.116
Human
gtp catabolic processGO:00061842370.102
Human
positive regulation of cellular amine metabolic processGO:003324070.097
post embryonic developmentGO:000979120.091
positive regulation of cellular amino acid metabolic processGO:004576430.091
regulation of lamellipodium morphogenesisGO:200039240.090
Human
nucleoside catabolic processGO:00091644080.087
Human
ribonucleoside triphosphate catabolic processGO:00092033910.084
Human
gtp metabolic processGO:00460392390.083
Human
single organism membrane organizationGO:00448022680.079
mapk cascadeGO:00001652880.076
nucleotide catabolic processGO:00091664080.075
Human
regulation of cellular amino acid metabolic processGO:000652160.073
purine nucleoside triphosphate metabolic processGO:00091444120.070
Human
regulation of cell motilityGO:20001452990.065
Human
system processGO:00030083490.065
negative regulation of protein metabolic processGO:00512483910.064
membrane organizationGO:00610242920.061
regulation of cell migrationGO:00303342890.060
Human
purine nucleoside triphosphate catabolic processGO:00091463920.060
Human
transmembrane transportGO:00550853990.059
regulation of cellular amine metabolic processGO:0033238110.058
nucleoside phosphate catabolic processGO:19012924120.056
Human
positive regulation of mapk cascadeGO:00434101900.056
organophosphate catabolic processGO:00464344300.053
Human
regulation of peptidase activityGO:00525471800.053
glycosyl compound catabolic processGO:19016584130.052
Human
small gtpase mediated signal transductionGO:0007264780.051
response to nitrogen compoundGO:19016981840.050
cellular amine metabolic processGO:0044106410.050
locomotory behaviorGO:000762610.050
regulation of intracellular transportGO:00323861950.049
regulation of cytoskeleton organizationGO:00514931770.049
regulation of apoptotic signaling pathwayGO:20012331750.047
guanosine containing compound catabolic processGO:19010692390.046
Human
multicellular organismal agingGO:001025930.045
regulation of cellular component movementGO:00512703340.045
Human
positive regulation of cell deathGO:00109422630.045
Human
regenerationGO:003109940.044
regulation of establishment of protein localizationGO:00702012420.044
ras protein signal transductionGO:0007265730.044
cellular response to oxygen containing compoundGO:19017012760.044
positive regulation of cell motilityGO:20001471770.044
Human
positive regulation of cellular component movementGO:00512721810.043
Human
positive regulation of protein transportGO:00512221350.043
purine ribonucleoside triphosphate metabolic processGO:00092054110.043
Human
purine nucleoside catabolic processGO:00061523980.043
Human
single organism cellular localizationGO:19025803320.043
regulation of protein transportGO:00512232130.042
regulation of cellular response to stressGO:00801352440.042
signal transduction by phosphorylationGO:00230142970.041
protein localization to organelleGO:00333652800.041
amine metabolic processGO:0009308440.041
cell substrate junction assemblyGO:0007044350.041
Human
apoptotic signaling pathwayGO:00971902680.041
regulation of cell cycleGO:00517263930.041
guanosine containing compound metabolic processGO:19010682440.041
Human
mitotic cell cycleGO:00002783260.041
purine nucleotide catabolic processGO:00061954050.040
Human
regulation of cellular ketone metabolic processGO:0010565500.040
cellular macromolecular complex assemblyGO:00346223240.040
segmentationGO:003528240.040
glial cell migrationGO:000834740.040
regulation of cellular component biogenesisGO:00440872810.039
negative regulation of cell deathGO:00605483450.039
ameboidal type cell migrationGO:00016671350.039
Human
positive regulation of protein phosphorylationGO:00019343130.039
cellular ketone metabolic processGO:0042180800.039
regulation of protein localizationGO:00328802960.039
positive regulation of ras gtpase activityGO:00323201170.039
Human
negative regulation of cellular protein metabolic processGO:00322693530.039
purine ribonucleoside catabolic processGO:00461303980.038
Human
regulation of endopeptidase activityGO:00525481700.038
regulation of proteolysisGO:00301622930.037
nucleoside triphosphate catabolic processGO:00091433940.036
Human
organelle inheritanceGO:004830820.036
positive regulation of hydrolase activityGO:00513453310.036
Human
neuron projection regenerationGO:003110210.036
oogenesisGO:004847720.036
activation of mapkkk activityGO:000018570.035
actin filament based processGO:00300292240.035
extrinsic apoptotic signaling pathwayGO:00971911190.035
lipid localizationGO:00108761060.034
regulation of mitotic cell cycleGO:00073461890.034
determination of adult lifespanGO:000834020.034
positive regulation of phosphorylationGO:00423273940.034
positive regulation of apoptotic processGO:00430652460.034
Human
nucleocytoplasmic transportGO:00069131760.033
positive regulation of actin filament bundle assemblyGO:0032233250.033
positive regulation of transferase activityGO:00513472270.033
regulation of nucleotide metabolic processGO:00061402690.033
Human
purine ribonucleoside metabolic processGO:00461284370.032
Human
regulation of cytoplasmic transportGO:19036491490.032
neuromuscular junction developmentGO:000752830.032
lipid transportGO:0006869900.032
stress activated mapk cascadeGO:0051403930.032
negative regulation of multicellular organismal processGO:00512413170.031
regulation of cell differentiationGO:00455953930.031
Human
intracellular protein transportGO:00068862700.031
regulation of cell cycle processGO:00105642660.031
negative regulation of apoptotic processGO:00430663160.031
keratinizationGO:003142420.030
multicellular organismal response to stressGO:003355510.030
organelle assemblyGO:00709251760.030
positive regulation of transportGO:00510503360.030
regulation of protein processingGO:00706131500.030
cell junction organizationGO:0034330790.030
Human
wound healingGO:00420601150.029
cellular component morphogenesisGO:00329893140.029
Human
positive regulation of cellular component organizationGO:00511303760.029
Human
female gamete generationGO:000729220.029
protein autophosphorylationGO:00467771230.029
positive regulation of gtp catabolic processGO:00331261660.029
Human
cellular lipid metabolic processGO:00442553030.029
positive regulation of cell migrationGO:00303351720.028
Human
positive regulation of nucleotide metabolic processGO:00459812300.028
Human
regulation of gtpase activityGO:00430871800.028
Human
rhythmic behaviorGO:000762220.028
regulation of protein kinase activityGO:00458592890.028
regulation of extrinsic apoptotic signaling pathwayGO:2001236850.027
organ formationGO:004864530.027
peptidyl tyrosine phosphorylationGO:00181081700.027
cell matrix adhesionGO:0007160850.027
Human
peptidyl tyrosine modificationGO:00182121700.027
sterol transmembrane transportGO:003538240.027
cell divisionGO:00513011680.027
ribonucleoprotein complex assemblyGO:0022618780.027
cell projection organizationGO:00300302520.027
Human Mouse
regulation of kinase activityGO:00435493140.027
negative regulation of catalytic activityGO:00430863350.027
rna processingGO:00063962550.027
negative regulation of hydrolase activityGO:00513461820.026
mitotic cell cycle processGO:19030472860.026
regulation of intracellular estrogen receptor signaling pathwayGO:0033146130.026
negative regulation of endopeptidase activityGO:0010951840.026
matingGO:000761810.026
regulation of cysteine type endopeptidase activityGO:20001161270.026
cell adhesionGO:00071553250.026
Human
neuron fate commitmentGO:004866320.026
inner ear morphogenesisGO:004247240.026
nuclear transportGO:00511691790.026
positive regulation of intracellular protein transportGO:0090316760.026
cellular response to abiotic stimulusGO:00712141170.025
positive regulation of cell adhesionGO:0045785840.025
Human
cellular amino acid metabolic processGO:00065201160.025
negative regulation of cellular component organizationGO:00511292350.025
regulation of anatomical structure morphogenesisGO:00226032860.025
Human
morphogenesis of embryonic epitheliumGO:001633140.025
regulation of protein localization to nucleusGO:1900180850.025
defense responseGO:00069523150.024
response to woundingGO:00096111680.024
response to organonitrogen compoundGO:00102431560.024
sterol transportGO:0015918390.024
purine containing compound catabolic processGO:00725234110.024
Human
cell substrate adhesionGO:00315891320.024
Human
cell junction assemblyGO:0034329670.024
Human
negative regulation of proteolysisGO:00458611320.024
positive regulation of intracellular transportGO:00323881040.024
protein processingGO:00164852260.024
negative regulation of protein processingGO:00109551420.024
protein catabolic processGO:00301633250.024
hematopoietic or lymphoid organ developmentGO:00485341860.024
positive regulation of cell proliferationGO:00082843010.024
ribonucleoprotein complex biogenesisGO:00226131160.023
hemopoiesisGO:00300971800.023
regulation of actin cytoskeleton organizationGO:00329561160.023
negative regulation of peptidase activityGO:0010466910.023
forebrain neuron differentiationGO:002187930.023
ion transmembrane transportGO:00342203380.023
maintenance of locationGO:00512351120.023
nucleoside triphosphate metabolic processGO:00091414220.023
Human
positive regulation of cellular catabolic processGO:00313312840.023
Human
oocyte developmentGO:004859910.023
dephosphorylationGO:00163112090.023
motor neuron axon guidanceGO:000804520.022
protein maturationGO:00516042330.022
carbohydrate derivative biosynthetic processGO:19011372070.022
regulation of peptidyl serine phosphorylationGO:0033135500.022
regulation of rho protein signal transductionGO:0035023790.022
Human
midgut developmentGO:000749410.022
positive regulation of kinase activityGO:00336742040.022
vacuole organizationGO:0007033440.022
positive regulation of catabolic processGO:00098963100.022
Human
response to decreased oxygen levelsGO:0036293960.022
cellular response to endogenous stimulusGO:00714953360.022
ribonucleoside triphosphate metabolic processGO:00091994120.022
Human
regulation of small gtpase mediated signal transductionGO:00510561560.022
Human
regulation of mapk cascadeGO:00434082620.022
growthGO:00400072020.022
biological adhesionGO:00226103310.022
Human
positive regulation of cytoplasmic transportGO:1903651820.022
protein targetingGO:00066051870.022
protein localization to membraneGO:00726571600.022
negative regulation of protein modification processGO:00314002000.022
salivary gland morphogenesisGO:000743540.021
negative regulation of phosphate metabolic processGO:00459362670.021
tripartite regional subdivisionGO:000735120.021
ribonucleoprotein complex subunit organizationGO:0071826810.021
regulation of intracellular protein transportGO:00331571230.021
cellular protein complex assemblyGO:00436231880.021
forebrain generation of neuronsGO:002187230.021
regulation of protein complex assemblyGO:00432541470.021
positive regulation of immune system processGO:00026842830.021
circadian behaviorGO:004851220.021
regulation of secretionGO:00510461940.021
protein localization to nucleusGO:00345041360.021
lipid metabolic processGO:00066293810.021
protein importGO:00170381300.021
regulation of purine nucleotide metabolic processGO:19005422640.021
Human
positive regulation of programmed cell deathGO:00430682490.021
Human
hindbrain developmentGO:003090230.021
negative regulation of programmed cell deathGO:00430693210.020
stress activated protein kinase signaling cascadeGO:0031098940.020
positive regulation of immune responseGO:00507781590.020
regulation of mitosisGO:0007088630.020
muscle structure developmentGO:0061061980.020
regulation of cardiac muscle cell proliferationGO:006004340.020
negative regulation of protein maturationGO:19033181420.020
cardiac muscle cell contractionGO:008600340.020
regulation of bindingGO:00510981110.020
regulation of cysteine type endopeptidase activity involved in apoptotic processGO:00432811160.020
cell growthGO:00160491600.020
fibroblast migrationGO:001076170.020
Human
plasma membrane organizationGO:00070091150.020
response to oxygen containing compoundGO:19017003690.020
regulation of cell developmentGO:00602841610.020
Human
generation of neuronsGO:00486991520.020
nuclear divisionGO:00002801280.020
positive regulation of protein localization to nucleusGO:1900182480.019
epithelium developmentGO:00604292270.019
regulation of cell substrate adhesionGO:0010810680.019
Human
organelle fissionGO:00482851490.019
cellular response to growth factor stimulusGO:00713631970.019
protein polymerizationGO:0051258710.019
stress fiber assemblyGO:0043149400.019
establishment of protein localization to organelleGO:00725941720.019
regulation of cell divisionGO:00513021160.019
blood circulationGO:00080151130.019
regulation of protein polymerizationGO:0032271630.019
astrocyte cell migrationGO:004361510.019
positive regulation of peptidyl serine phosphorylationGO:0033138420.019
single organism nuclear importGO:19025931040.019
positive regulation of defense responseGO:0031349870.019
spermatid differentiationGO:004851540.019
response to inorganic substanceGO:00100351270.019
regulation of protein maturationGO:19033171500.019
cellular response to nitrogen compoundGO:19016991440.019
positive regulation of synapse structural plasticityGO:005183520.019
ribonucleotide catabolic processGO:00092614050.018
Human
forebrain neuron developmentGO:002188420.018
response to abiotic stimulusGO:00096283360.018
cation transportGO:00068123310.018
peptidyl serine phosphorylationGO:00181051010.018
regulation of actin filament bundle assemblyGO:0032231360.018
response to oxygen levelsGO:00704821000.018
positive regulation of cytokine productionGO:00018191670.018
single organism cell adhesionGO:00986021790.018
Human
regulation of transferase activityGO:00513383550.018
chemotaxisGO:00069351570.018
positive regulation of map kinase activityGO:0043406800.018
regulation of membrane potentialGO:0042391950.018
purine ribonucleotide catabolic processGO:00091544040.018
Human
response to peptideGO:1901652650.018
nuclear migrationGO:000709710.018
activation of protein kinase activityGO:0032147900.018
positive regulation of protein kinase activityGO:00458601900.018
positive regulation of cellular component biogenesisGO:00440891580.018
response to external biotic stimulusGO:00432072610.018
metal ion transportGO:00300012720.018
organic hydroxy compound transportGO:0015850630.018
axon regenerationGO:003110310.018
immune system developmentGO:00025201950.018
positive regulation of stress activated mapk cascadeGO:0032874600.018
cell morphogenesisGO:00009022960.018
Human
regulation of stress activated protein kinase signaling cascadeGO:0070302850.018
tissue regenerationGO:004224630.018
negative regulation of transcription from rna polymerase ii promoterGO:00001222810.018
blastoderm segmentationGO:000735020.018
regulation of protein serine threonine kinase activityGO:00719001790.018
positive regulation of locomotionGO:00400171860.017
Human
response to hypoxiaGO:0001666960.017
positive regulation of cell differentiationGO:00455972110.017
Human
mrna metabolic processGO:00160711750.017
anterior posterior axis specification embryoGO:000859520.017
regulation of nucleocytoplasmic transportGO:0046822980.017
striated muscle contractionGO:0006941520.017
histone modificationGO:00165702510.017
ion homeostasisGO:00508012300.017
regulation of neurotransmitter secretionGO:004692830.017
positive regulation of protein import into nucleusGO:0042307460.017
spermatid developmentGO:000728640.017
specification of organ identityGO:001009230.017
regulation of nuclear divisionGO:0051783650.016
actin filament bundle assemblyGO:0051017540.016
positive regulation of organelle organizationGO:00106381950.016
positive regulation of protein tyrosine kinase activityGO:0061098240.016
response to organic cyclic compoundGO:00140702040.016
negative regulation of apoptotic signaling pathwayGO:2001234970.016
regulation of stress activated mapk cascadeGO:0032872840.016
adult locomotory behaviorGO:000834410.016
intracellular receptor signaling pathwayGO:00305221040.016
mitotic nuclear divisionGO:00070671190.016
regulation of meiotic cell cycleGO:005144540.016
actin filament organizationGO:00070151280.016
cell migration involved in gastrulationGO:004207410.016
vesicle mediated transportGO:00161923710.016
immune effector processGO:00022521590.016
cerebral cortex radially oriented cell migrationGO:002179910.016
positive regulation of apoptotic signaling pathwayGO:2001235700.016
actin filament bundle organizationGO:0061572540.016
hair cell differentiationGO:003531520.016
regulation of vesicle mediated transportGO:00606271300.016
innate immune responseGO:00450871780.016
actin cytoskeleton organizationGO:00300362070.016
regulation of synaptic plasticityGO:004816730.016
positive regulation of secretion by cellGO:19035321080.016
negative regulation of cell proliferationGO:00082852280.016
positive regulation of purine nucleotide metabolic processGO:19005442270.016
Human
positive regulation of behaviorGO:0048520600.016
muscle contractionGO:0006936730.016
contact inhibitionGO:006024230.016
regulation of response to external stimulusGO:00321012220.015
heart formationGO:006091420.015
cerebral cortex cell migrationGO:002179530.015
cytoplasmic transportGO:00164823790.015
positive regulation of nucleotide catabolic processGO:00308131850.015
Human
reactive oxygen species biosynthetic processGO:190340940.015
neuroblast proliferationGO:000740540.015
t cell activationGO:0042110990.015
cell developmentGO:00484683280.015
Human
activation of immune responseGO:00022531140.015
metencephalon developmentGO:002203720.015
associative learningGO:000830610.015
sequestering of calcium ionGO:0051208170.015
mitotic cell cycle phase transitionGO:00447721620.015
sequestering of metal ionGO:0051238240.015
regulation of protein catabolic processGO:00421761550.015
immune responseGO:00069553070.015
regulation of cytokine productionGO:00018172320.014
regulation of gtp catabolic processGO:00331241800.014
Human
syncytium formation by plasma membrane fusionGO:000076820.014
establishment of tissue polarityGO:000716430.014
oocyte differentiationGO:000999420.014
muscle cell fate commitmentGO:004269340.014
wnt signaling pathwayGO:00160551560.014
regulation of dephosphorylationGO:0035303960.014
embryo developmentGO:00097901230.014
positive regulation of peptidyl tyrosine phosphorylationGO:0050731850.014
positive regulation of stress activated protein kinase signaling cascadeGO:0070304610.014
regulation of ras gtpase activityGO:00323181280.014
Human
taxisGO:00423301570.014
cellular response to peptide hormone stimulusGO:0071375560.014
cell cell junction organizationGO:0045216690.014
Human
cell projection assemblyGO:00300311260.014
Mouse
covalent chromatin modificationGO:00165692540.014
tissue morphogenesisGO:0048729960.014
jnk cascadeGO:0007254800.014
response to virusGO:00096151260.014
protein modification by small protein conjugationGO:00324463420.014
cochlea developmentGO:009010210.014
cation transmembrane transportGO:00986552380.014
cell projection morphogenesisGO:00488581290.014
Human
response to lipidGO:00339932060.014
reactive oxygen species metabolic processGO:0072593750.014
regulation of actin filament lengthGO:0030832560.014
limbic system developmentGO:002176130.014
ribonucleoside catabolic processGO:00424544060.014
Human
somatic muscle developmentGO:000752510.014
regulation of intracellular steroid hormone receptor signaling pathwayGO:0033143320.013
cellular response to organonitrogen compoundGO:00714171240.013
sensory perceptionGO:00076001030.013
blood vessel developmentGO:00015681720.013
response to fungusGO:000962040.013
protein targeting to nucleusGO:00447441040.013
regulation of nucleotide catabolic processGO:00308112050.013
Human
positive regulation of endothelial cell migrationGO:0010595390.013
regulation of ion transportGO:00432691890.013
myoblast fusionGO:000752010.013
regulation of heart growthGO:006042040.013
positive regulation of developmental processGO:00510943140.013
Human
regulation of locomotionGO:00400123290.013
Human
positive regulation of pseudopodium assemblyGO:003127470.013
positive regulation of intracellular estrogen receptor signaling pathwayGO:003314850.013
neurogenesisGO:00220081690.013
cation homeostasisGO:00550801890.013
ectodermal placode developmentGO:007169610.013
negative regulation of transferase activityGO:00513481240.013
regulation of cell morphogenesisGO:00226041530.013
Human
cellular response to dna damage stimulusGO:00069743790.013
neuron projection developmentGO:00311751060.013
positive regulation of extrinsic apoptotic signaling pathwayGO:2001238260.013
nucleus localizationGO:005164710.013
response to other organismGO:00517072610.013
cerebellum developmentGO:002154920.013
positive regulation of reactive oxygen species biosynthetic processGO:190342820.013
cell fate determinationGO:000170930.013
substrate adhesion dependent cell spreadingGO:0034446410.013
Human
positive regulation of lymphocyte activationGO:0051251730.013
nuclear importGO:00511701060.013
regulation of map kinase activityGO:00434051080.013
inorganic cation transmembrane transportGO:00986621940.013
peripheral nervous system developmentGO:000742220.013
ubiquitin dependent protein catabolic processGO:00065112060.013
regulation of cell growthGO:00015581350.013
compound eye developmentGO:004874910.013
response to hormoneGO:00097251750.013
monocarboxylic acid metabolic processGO:00327871850.013
divalent metal ion transportGO:00708381520.013
small molecule biosynthetic processGO:00442831570.013
negative regulation of phosphorus metabolic processGO:00105632670.013
establishment of planar polarityGO:000173630.013
protein import into nucleusGO:00066061040.013
negative regulation of protein kinase activityGO:0006469980.013
cellular response to hormone stimulusGO:00328701250.012
myosin filament assemblyGO:003103420.012
g protein coupled receptor signaling pathwayGO:00071862070.012
visual behaviorGO:000763220.012
response to insulinGO:0032868450.012
regulation of neural precursor cell proliferationGO:200017740.012
positive regulation of cell cycleGO:00457871400.012
protein localization to plasma membraneGO:0072659930.012
secretionGO:00469032540.012
response to growth factorGO:00708482050.012
metal ion homeostasisGO:00550651690.012
regulation of protein ubiquitinationGO:0031396950.012
regulation of protein import into nucleusGO:0042306780.012
regulation of cell adhesionGO:00301551660.012
Human
muscle system processGO:0003012810.012
anion transportGO:00068201610.012
somatic stem cell maintenanceGO:003501940.012
sensory perception of mechanical stimulusGO:0050954370.012
negative regulation of cysteine type endopeptidase activityGO:2000117480.012
negative regulation of kinase activityGO:00336731060.012
cellular component disassemblyGO:0022411920.012
positive regulation of reactive oxygen species metabolic processGO:2000379240.012
actin mediated cell contractionGO:0070252120.012
cellular macromolecule catabolic processGO:00442653800.012
intracellular steroid hormone receptor signaling pathwayGO:0030518610.012
regulation of nervous system developmentGO:0051960880.012
actomyosin structure organizationGO:0031032590.012
calcium ion transmembrane transportGO:0070588760.012
positive regulation of cysteine type endopeptidase activityGO:2001056790.012
copulationGO:000762010.012
lipid biosynthetic processGO:00086101770.012
regulation of excitatory postsynaptic membrane potentialGO:006007910.012
regulation of reactive oxygen species biosynthetic processGO:190342630.012
cellular chemical homeostasisGO:00550821800.012
circulatory system developmentGO:00723592620.012
positive regulation of cell substrate adhesionGO:0010811370.012
Human
ribonucleoside monophosphate metabolic processGO:00091611870.012
blastocyst developmentGO:000182430.011
phospholipid metabolic processGO:0006644990.011
response to oxidative stressGO:00069791210.011
actin polymerization or depolymerizationGO:0008154560.011
endosomal transportGO:00161971290.011
epithelium migrationGO:00901321190.011
actin filament based movementGO:0030048170.011
response to peptide hormoneGO:0043434610.011
dna repairGO:00062811980.011
regulation of cysteine type endopeptidase activity involved in execution phase of apoptosisGO:200127030.011
ectodermal placode formationGO:006078810.011
regulation of secretion by cellGO:19035301770.011
nitrogen compound transportGO:00717051910.011
cellular amide metabolic processGO:0043603690.011
purine ribonucleoside monophosphate metabolic processGO:00091671860.011
regulation of actin polymerization or depolymerizationGO:0008064560.011
negative regulation of cysteine type endopeptidase activity involved in apoptotic processGO:0043154460.011
positive regulation of natural killer cell mediated cytotoxicityGO:0045954110.011
regulation of multi organism processGO:00439001570.011
semaphorin plexin signaling pathwayGO:007152640.011
rna splicingGO:00083801310.011

ARHGEF6 disease predictions

DiseaseDO term IDSizeProbabilityFunc Analog Org
musculoskeletal system diseaseDOID:172230.049
disease of metabolismDOID:00146672950.024
muscular diseaseDOID:00800001140.023
myopathyDOID:4231040.021
muscle tissue diseaseDOID:661130.021
nervous system diseaseDOID:8634310.019
sensory system diseaseDOID:00501552030.019
eye diseaseDOID:56141490.019
eye and adnexa diseaseDOID:14921500.019
connective tissue diseaseDOID:651090.018
central nervous system diseaseDOID:3311860.016
inherited metabolic disorderDOID:6552420.015
cardiovascular system diseaseDOID:12871060.014
intrinsic cardiomyopathyDOID:0060036500.014
heart diseaseDOID:114680.014
cardiomyopathyDOID:0050700500.014
bone diseaseDOID:0080001880.013
cancerDOID:1621670.013
disease of cellular proliferationDOID:145661740.013
retinal diseaseDOID:56791180.013
muscular dystrophyDOID:9884510.012