Homo sapiens

113 known processes

CENPE

centromere protein E, 312kDa

(Aliases: KIF10)

CENPE biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
chromosome segregationGO:00070591140.967
Mouse
meiotic chromosome segregationGO:004513240.914
maintenance of location in cellGO:0051651620.882
Mouse
neuroblast divisionGO:005505710.858
sister chromatid segregationGO:0000819540.816
Mouse
regulation of microtubule based processGO:0032886740.720
Mouse
nuclear divisionGO:00002801280.716
spindle assembly involved in mitosisGO:0090307120.673
mitotic cell cycle processGO:19030472860.673
microtubule anchoringGO:0034453240.628
Mouse
attachment of spindle microtubules to kinetochoreGO:0008608170.608
Mouse
maintenance of protein locationGO:0045185570.580
Mouse
nucleoside triphosphate metabolic processGO:00091414220.555
microtubule polymerization or depolymerizationGO:0031109370.550
mitotic nuclear divisionGO:00070671190.529
cell divisionGO:00513011680.526
regulation of cytoskeleton organizationGO:00514931770.492
Mouse
attachment of mitotic spindle microtubules to kinetochoreGO:005131530.491
spindle elongationGO:005123140.483
organelle fissionGO:00482851490.469
regulation of microtubule polymerization or depolymerizationGO:0031110270.435
maintenance of locationGO:00512351120.426
Mouse
male meiosisGO:000714010.422
regulation of protein localizationGO:00328802960.412
Mouse
microtubule based processGO:00070172100.396
Mouse
nucleoside triphosphate catabolic processGO:00091433940.375
mitotic sister chromatid segregationGO:0000070530.366
Mouse
sister chromatid biorientationGO:003113420.364
regulation of cell cycleGO:00517263930.345
ribonucleoside monophosphate catabolic processGO:00091581580.334
cellular component disassemblyGO:0022411920.325
nucleoside monophosphate catabolic processGO:00091251590.321
kinetochore organizationGO:005138380.314
protein depolymerizationGO:0051261300.313
purine ribonucleoside monophosphate catabolic processGO:00091691580.294
ribonucleotide catabolic processGO:00092614050.290
ribonucleoside triphosphate catabolic processGO:00092033910.288
regulation of cell cycle processGO:00105642660.279
regulation of cell divisionGO:00513021160.259
regulation of microtubule cytoskeleton organizationGO:0070507610.249
Mouse
purine nucleoside triphosphate catabolic processGO:00091463920.246
mitotic spindle elongationGO:000002240.245
purine ribonucleoside catabolic processGO:00461303980.231
negative regulation of cellular component organizationGO:00511292350.230
Mouse
mitotic spindle midzone assemblyGO:005125640.226
ribonucleoside catabolic processGO:00424544060.224
nucleoside phosphate catabolic processGO:19012924120.218
cellular protein complex disassemblyGO:0043624360.211
purine nucleoside catabolic processGO:00061523980.208
maintenance of protein location in cellGO:0032507560.207
Mouse
metaphase plate congressionGO:0051310180.201
mitotic spindle organizationGO:0007052270.201
purine nucleoside triphosphate metabolic processGO:00091444120.194
microtubule based movementGO:0007018320.194
regulation of chromosome segregationGO:0051983440.186
purine nucleoside monophosphate catabolic processGO:00091281580.182
negative regulation of organelle organizationGO:00106391260.180
Mouse
purine nucleotide catabolic processGO:00061954050.176
stem cell divisionGO:001714520.176
spindle organizationGO:0007051530.173
mitotic cell cycleGO:00002783260.160
nucleus localizationGO:005164710.146
regulation of intrinsic apoptotic signaling pathwayGO:2001242720.144
blastocyst developmentGO:000182430.133
purine ribonucleoside triphosphate catabolic processGO:00092073910.132
purine ribonucleoside triphosphate metabolic processGO:00092054110.128
organophosphate catabolic processGO:00464344300.127
somatic stem cell divisionGO:004810310.126
microtubule cytoskeleton organization involved in mitosisGO:1902850150.125
microtubule cytoskeleton organizationGO:00002261760.122
Mouse
purine ribonucleotide catabolic processGO:00091544040.122
regulation of mitotic sister chromatid segregationGO:0033047270.116
ribonucleoside monophosphate metabolic processGO:00091611870.116
post embryonic developmentGO:000979120.116
regulation of locomotionGO:00400123290.115
organelle assemblyGO:00709251760.113
protein localization to organelleGO:00333652800.112
positive regulation of protein phosphorylationGO:00019343130.103
regulation of cellular component biogenesisGO:00440872810.102
negative regulation of microtubule polymerization or depolymerizationGO:0031111170.100
neuronal stem cell divisionGO:003644510.099
centrosome organizationGO:0051297580.099
ribonucleoside triphosphate metabolic processGO:00091994120.097
purine ribonucleoside metabolic processGO:00461284370.095
spindle midzone assemblyGO:005125540.094
microtubule bundle formationGO:0001578150.092
cellular macromolecular complex assemblyGO:00346223240.092
atp catabolic processGO:00062001570.089
glycosyl compound catabolic processGO:19016584130.086
canonical wnt signaling pathwayGO:00600701160.085
regulation of protein catabolic processGO:00421761550.085
negative regulation of protein metabolic processGO:00512483910.084
Mouse
protein complex disassemblyGO:0043241520.083
establishment of organelle localizationGO:0051656590.081
nucleoside catabolic processGO:00091644080.080
neuroblast proliferationGO:000740540.080
dna packagingGO:0006323770.078
regulation of transferase activityGO:00513383550.078
cytoskeleton dependent cytokinesisGO:0061640220.077
spindle assemblyGO:0051225290.076
nucleotide catabolic processGO:00091664080.076
cellular macromolecule catabolic processGO:00442653800.075
embryo developmentGO:00097901230.073
positive regulation of protein transportGO:00512221350.073
cytokinesis completion of separationGO:000710930.073
cardiovascular system developmentGO:00723582620.073
regulation of spindle organizationGO:0090224100.072
cytoplasmic transportGO:00164823790.071
protein localization to chromosome centromeric regionGO:0071459120.071
regulation of establishment of protein localizationGO:00702012420.070
negative regulation of mitotic metaphase anaphase transitionGO:0045841170.069
Mouse
positive regulation of cell cycleGO:00457871400.069
Mouse
regulation of cellular component movementGO:00512703340.068
negative regulation of cell deathGO:00605483450.068
regulation of protein kinase activityGO:00458592890.067
nuclear migrationGO:000709710.066
mitotic centrosome separationGO:000710010.065
macromolecular complex disassemblyGO:0032984600.065
spindle stabilizationGO:004314640.065
atp metabolic processGO:00460341760.064
positive regulation of transportGO:00510503360.064
neuron differentiationGO:00301821380.064
metaphase anaphase transition of cell cycleGO:0044784210.064
meiotic nuclear divisionGO:0007126100.064
negative regulation of proteolysisGO:00458611320.061
Mouse
protein polymerizationGO:0051258710.061
chromosome separationGO:0051304230.060
Mouse
nucleoside monophosphate metabolic processGO:00091231910.059
intracellular protein transportGO:00068862700.058
regulation of mitosisGO:0007088630.058
purine nucleoside monophosphate metabolic processGO:00091261860.057
positive regulation of kinase activityGO:00336742040.057
positive regulation of cytoplasmic transportGO:1903651820.056
negative regulation of protein depolymerizationGO:1901880170.056
positive regulation of protein kinase activityGO:00458601900.056
protein processingGO:00164852260.056
Mouse
single organism cellular localizationGO:19025803320.055
neurogenesisGO:00220081690.055
regulation of kinase activityGO:00435493140.055
negative regulation of protein complex disassemblyGO:0043242200.054
microtubule polymerizationGO:0046785180.054
regulation of neuron differentiationGO:0045664700.054
microtubule organizing center organizationGO:0031023620.053
regulation of cell migrationGO:00303342890.053
protein ubiquitinationGO:00165673140.053
regulation of intracellular transportGO:00323861950.052
regulation of cytoplasmic transportGO:19036491490.051
cytokinetic processGO:0032506120.050
embryonic epithelial tube formationGO:000183840.050
regulation of cell developmentGO:00602841610.050
positive regulation of intracellular protein transportGO:0090316760.050
protein importGO:00170381300.050
sister chromatid cohesionGO:0007062240.049
epithelium developmentGO:00604292270.049
regenerationGO:003109940.048
regulation of mitotic spindle organizationGO:006023660.047
regulation of wnt signaling pathwayGO:00301111230.047
nervous system developmentGO:00073992930.047
centrosome cycleGO:0007098320.047
regulation of mitotic cell cycleGO:00073461890.046
establishment of nucleus localizationGO:004002310.046
ubiquitin dependent protein catabolic processGO:00065112060.046
regulation of protein serine threonine kinase activityGO:00719001790.045
regulation of protein transportGO:00512232130.045
positive regulation of phosphorylationGO:00423273940.045
tissue regenerationGO:004224630.044
positive regulation of intracellular transportGO:00323881040.043
negative regulation of cellular protein catabolic processGO:1903363380.042
Mouse
negative regulation of cell cycle processGO:00109481210.041
Mouse
circulatory system developmentGO:00723592620.041
regulation of protein processingGO:00706131500.041
Mouse
positive regulation of cellular component organizationGO:00511303760.040
Mouse
centromeric sister chromatid cohesionGO:007060130.040
regulation of cell differentiationGO:00455953930.040
reproductive processGO:00224141060.039
reciprocal meiotic recombinationGO:000713140.039
regulation of cellular ketone metabolic processGO:0010565500.039
positive regulation of cytokinesisGO:0032467290.039
regulation of cellular protein catabolic processGO:1903362960.039
protein targetingGO:00066051870.038
mitotic cytokinesisGO:0000281190.038
proteasome mediated ubiquitin dependent protein catabolic processGO:00431611560.037
positive regulation of wnt signaling pathwayGO:0030177540.037
organelle localizationGO:0051640840.037
modification dependent macromolecule catabolic processGO:00436322120.037
chromatin modificationGO:00165682980.037
purine containing compound catabolic processGO:00725234110.036
regulation of intracellular protein transportGO:00331571230.036
regulation of proteasomal ubiquitin dependent protein catabolic processGO:0032434710.036
negative regulation of mitotic sister chromatid separationGO:2000816170.036
Mouse
purine ribonucleoside monophosphate metabolic processGO:00091671860.036
positive regulation of catabolic processGO:00098963100.035
Mouse
centrosome duplicationGO:0051298280.035
negative regulation of mitotic cell cycleGO:00459301020.034
Mouse
regulation of nucleocytoplasmic transportGO:0046822980.034
positive regulation of cellular catabolic processGO:00313312840.033
Mouse
actin filament based processGO:00300292240.033
centrosome separationGO:005129930.033
establishment of cell polarityGO:0030010220.032
intrinsic apoptotic signaling pathwayGO:00971931270.032
positive regulation of apoptotic processGO:00430652460.032
wnt signaling pathwayGO:00160551560.032
heart developmentGO:0007507950.032
positive regulation of transferase activityGO:00513472270.032
morphogenesis of embryonic epitheliumGO:001633140.031
apoptotic signaling pathwayGO:00971902680.031
nucleocytoplasmic transportGO:00069131760.031
positive regulation of programmed cell deathGO:00430682490.031
establishment or maintenance of cell polarityGO:0007163310.030
regulation of cellular amino acid metabolic processGO:000652160.030
regulation of protein maturationGO:19033171500.030
Mouse
positive regulation of canonical wnt signaling pathwayGO:0090263330.030
negative regulation of protein maturationGO:19033181420.029
Mouse
cellular amine metabolic processGO:0044106410.029
reproductive system developmentGO:0061458560.029
generation of neuronsGO:00486991520.029
dna conformation changeGO:00711031130.028
primary neural tube formationGO:001402030.028
cellular ketone metabolic processGO:0042180800.028
negative regulation of sister chromatid segregationGO:0033046170.028
Mouse
negative regulation of cytoskeleton organizationGO:0051494450.027
protein dephosphorylationGO:0006470810.027
regulation of protein complex assemblyGO:00432541470.027
regulation of proteolysisGO:00301622930.027
regulation of cellular amine metabolic processGO:0033238110.027
positive regulation of protein import into nucleusGO:0042307460.027
protein maturationGO:00516042330.027
Mouse
cellular protein complex assemblyGO:00436231880.027
negative regulation of cell divisionGO:0051782310.027
Mouse
peptidyl serine modificationGO:00182091060.027
rap protein signal transductionGO:003248670.026
microtubule depolymerizationGO:0007019180.026
regulation of protein import into nucleusGO:0042306780.026
regulation of mitotic metaphase anaphase transitionGO:0030071260.026
single organism nuclear importGO:19025931040.026
metaphase anaphase transition of mitotic cell cycleGO:0007091210.025
brain morphogenesisGO:004885410.025
cell developmentGO:00484683280.025
protein targeting to nucleusGO:00447441040.025
neural tube closureGO:000184330.025
regulation of mitotic sister chromatid separationGO:0010965270.025
protein secretionGO:0009306980.025
negative regulation of cell cycleGO:00457861930.025
Mouse
mitotic metaphase plate congressionGO:0007080140.024
establishment of chromosome localizationGO:0051303200.024
negative regulation of programmed cell deathGO:00430693210.023
protein localization to nucleusGO:00345041360.023
cellular amino acid metabolic processGO:00065201160.023
meiosis iGO:000712740.023
single organism cell adhesionGO:00986021790.023
actin filament reorganizationGO:009052710.023
regulation of protein targetingGO:1903533910.023
cytokinesisGO:0000910960.023
proteolysis involved in cellular protein catabolic processGO:00516032440.023
meiotic cell cycleGO:0051321130.022
negative regulation of multicellular organismal processGO:00512413170.022
regulation of nervous system developmentGO:0051960880.022
reproductive structure developmentGO:0048608550.022
negative regulation of cellular protein metabolic processGO:00322693530.022
Mouse
posttranscriptional regulation of gene expressionGO:00106082130.022
positive regulation of cellular amino acid metabolic processGO:004576430.021
protein import into nucleusGO:00066061040.021
positive regulation of nfat protein import into nucleusGO:005153330.021
negative regulation of chromosome organizationGO:2001251480.021
Mouse
positive regulation of neural precursor cell proliferationGO:200017920.021
spindle assembly checkpointGO:0071173170.021
Mouse
nuclear importGO:00511701060.021
establishment of protein localization to organelleGO:00725941720.021
regulation of neurogenesisGO:0050767820.021
positive regulation of organelle organizationGO:00106381950.021
Mouse
negative regulation of protein phosphorylationGO:00019331400.021
regulation of sister chromatid segregationGO:0033045270.021
regulation of apoptotic signaling pathwayGO:20012331750.021
oogenesisGO:004847720.020
regulation of cell motilityGO:20001452990.020
positive regulation of nucleotide metabolic processGO:00459812300.020
positive regulation of protein localization to nucleusGO:1900182480.020
negative regulation of cellular catabolic processGO:0031330830.019
Mouse
regulation of protein depolymerizationGO:1901879220.019
negative regulation of protein processingGO:00109551420.019
Mouse
axoneme assemblyGO:003508230.019
biological adhesionGO:00226103310.019
positive regulation of purine nucleotide catabolic processGO:00331231850.019
regulation of neural precursor cell proliferationGO:200017740.018
mitotic spindle checkpointGO:0071174180.018
Mouse
reproductionGO:0000003630.018
regulation of chromosome organizationGO:00330441030.018
negative regulation of protein modification processGO:00314002000.018
actin cytoskeleton organizationGO:00300362070.018
chromatin organizationGO:00063253510.018
sex differentiationGO:0007548450.018
centromere complex assemblyGO:0034508100.018
protein catabolic processGO:00301633250.018
integrin activationGO:003362280.018
regulation of organelle assemblyGO:1902115400.017
negative regulation of catalytic activityGO:00430863350.017
embryo development ending in birth or egg hatchingGO:0009792340.017
negative regulation of apoptotic processGO:00430663160.017
regulation of cellular response to stressGO:00801352440.017
positive regulation of protein catabolic processGO:0045732750.017
Mouse
regulation of gtp catabolic processGO:00331241800.017
regulation of transcription factor import into nucleusGO:0042990390.017
secretionGO:00469032540.017
gtp catabolic processGO:00061842370.016
forebrain generation of neuronsGO:002187230.016
mitotic spindle assembly checkpointGO:0007094140.016
Mouse
proteasomal protein catabolic processGO:00104981760.016
cell morphogenesisGO:00009022960.016
telencephalon developmentGO:0021537170.016
signal transduction by phosphorylationGO:00230142970.016
cellular response to radiationGO:0071478650.016
protein modification by small protein conjugationGO:00324463420.016
regulation of cytokinesisGO:0032465450.016
regulation of bindingGO:00510981110.016
female gamete generationGO:000729220.015
dephosphorylationGO:00163112090.015
positive regulation of cytoskeleton organizationGO:0051495830.015
Mouse
activation of protein kinase activityGO:0032147900.015
cell projection organizationGO:00300302520.015
negative regulation of integrin activationGO:003362420.015
positive regulation of transcription factor import into nucleusGO:0042993250.015
cell morphogenesis involved in differentiationGO:00009041440.015
enzyme linked receptor protein signaling pathwayGO:00071673030.015
development of primary sexual characteristicsGO:0045137350.015
regulation of purine nucleotide metabolic processGO:19005422640.015
epithelial cell differentiationGO:00308551410.014
regulation of proteasomal protein catabolic processGO:0061136870.014
guanosine containing compound catabolic processGO:19010692390.014
response to woundingGO:00096111680.014
developmental process involved in reproductionGO:0003006660.014
vesicle mediated transportGO:00161923710.014
wound healingGO:00420601150.014
positive regulation of proteolysisGO:00458621420.014
Mouse
cellular response to iron ionGO:007128110.014
regulation of purine nucleotide catabolic processGO:00331212050.013
establishment of spindle localizationGO:0051293120.013
modification dependent protein catabolic processGO:00199412090.013
negative regulation of catabolic processGO:00098951040.013
Mouse
nuclear transportGO:00511691790.013
negative regulation of microtubule depolymerizationGO:0007026120.013
chromosome condensationGO:0030261150.013
endocytosisGO:00068971590.013
developmental growthGO:0048589480.013
regulation of meiosisGO:004002030.013
microtubule based transportGO:0010970210.013
peptidyl serine phosphorylationGO:00181051010.013
negative regulation of proteolysis involved in cellular protein catabolic processGO:1903051350.013
Mouse
positive regulation of nucleotide catabolic processGO:00308131850.013
cell activationGO:00017752130.013
actin cytoskeleton reorganizationGO:0031532370.013
regulation of cell morphogenesisGO:00226041530.013
regulation of protein stabilityGO:0031647870.013
regulation of anatomical structure morphogenesisGO:00226032860.012
response to lipidGO:00339932060.012
growthGO:00400072020.012
establishment of spindle orientationGO:005129490.012
cell projection morphogenesisGO:00488581290.012
negative regulation of phosphate metabolic processGO:00459362670.012
cytoskeleton dependent intracellular transportGO:0030705210.012
negative regulation of phosphorylationGO:00423261740.012
establishment of mitotic spindle localizationGO:004000180.012
regulation of nucleotide metabolic processGO:00061402690.012
regulation of cell adhesionGO:00301551660.012
positive regulation of cell proliferationGO:00082843010.012
muscle structure developmentGO:0061061980.012
negative regulation of cell differentiationGO:00455961710.012
negative regulation of metaphase anaphase transition of cell cycleGO:1902100170.012
Mouse
positive regulation of cell divisionGO:0051781590.012
Mouse
regulation of protein complex disassemblyGO:0043244280.012
cell cycle phase transitionGO:00447701730.012
regulation of proteolysis involved in cellular protein catabolic processGO:1903050910.012
regulation of gtpase activityGO:00430871800.012
peptidyl tyrosine phosphorylationGO:00181081700.012
amine metabolic processGO:0009308440.012
regulation of metaphase anaphase transition of cell cycleGO:1902099260.012
protein localization to kinetochoreGO:0034501100.012
response to radiationGO:00093141510.011
regulation of protein localization to nucleusGO:1900180850.011
cellular response to oxygen containing compoundGO:19017012760.011
cellular response to endogenous stimulusGO:00714953360.011
positive regulation of gtpase activityGO:00435471660.011
negative regulation of developmental processGO:00510932470.011
regulation of dna metabolic processGO:00510521530.011
regulation of endopeptidase activityGO:00525481700.011
regulation of response to woundingGO:19030341010.011
positive regulation of locomotionGO:00400171860.011
cell part morphogenesisGO:00329901370.011
anatomical structure homeostasisGO:00602491000.011
asymmetric neuroblast divisionGO:005505910.011
asymmetric stem cell divisionGO:009872210.011
neural tube formationGO:000184130.011
blood vessel morphogenesisGO:00485141620.011
cell adhesionGO:00071553250.011
gonad developmentGO:0008406340.011
tube closureGO:006060630.011
endomembrane system organizationGO:00102561960.011
maintenance of organelle locationGO:005165740.011
nucleic acid phosphodiester bond hydrolysisGO:00903051020.010
small gtpase mediated signal transductionGO:0007264780.010
negative regulation of proteasomal ubiquitin dependent protein catabolic processGO:0032435300.010
Mouse
negative regulation of chromosome segregationGO:0051985180.010
Mouse
anatomical structure formation involved in morphogenesisGO:00486462840.010
organ morphogenesisGO:00098871470.010
positive regulation of cell developmentGO:0010720920.010
protein autophosphorylationGO:00467771230.010
regulation of gene expression epigeneticGO:0040029730.010
protein oligomerizationGO:00512591730.010
neuron developmentGO:00486661130.010

CENPE disease predictions

DiseaseDO term IDSizeProbabilityFunc Analog Org
physical disorderDOID:0080015410.168
congenital nervous system abnormalityDOID:2490210.168
disease of cellular proliferationDOID:145661740.065
cancerDOID:1621670.065
immune system diseaseDOID:29141550.034
microcephalyDOID:1090760.018
organ system cancerDOID:00506861640.016
disease of metabolismDOID:00146672950.010
carbohydrate metabolic disorderDOID:2978550.010
congenital disorder of glycosylationDOID:5212260.010
inherited metabolic disorderDOID:6552420.010