Homo sapiens

89 known processes

NPAT

nuclear protein, ataxia-telangiectasia locus

(Aliases: p220,E14/NPAT,E14)

NPAT biological process predictions


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Biological processGO term IDProcess sizeProbabilityFunc Analog Org
cell cycle phase transitionGO:00447701730.134
cellular response to dna damage stimulusGO:00069743790.122
mitotic cell cycleGO:00002783260.095
mitotic cell cycle processGO:19030472860.090
mitotic cell cycle phase transitionGO:00447721620.082
post embryonic developmentGO:000979120.079
negative regulation of transcription from rna polymerase ii promoterGO:00001222810.070
negative regulation of cell cycleGO:00457861930.069
cellular amino acid metabolic processGO:00065201160.057
cellular amine metabolic processGO:0044106410.055
negative regulation of protein metabolic processGO:00512483910.054
regulation of cell cycleGO:00517263930.052
regulation of cellular amino acid metabolic processGO:000652160.052
dna repairGO:00062811980.050
regulation of cellular amine metabolic processGO:0033238110.047
regulation of cell differentiationGO:00455953930.046
amine metabolic processGO:0009308440.046
female gamete generationGO:000729220.045
negative regulation of cellular protein metabolic processGO:00322693530.044
negative regulation of developmental processGO:00510932470.043
protein maturationGO:00516042330.043
g1 s transition of mitotic cell cycleGO:0000082780.043
positive regulation of cell proliferationGO:00082843010.042
positive regulation of cellular amine metabolic processGO:003324070.041
regulation of meiotic cell cycleGO:005144540.041
cell fate determinationGO:000170930.041
ras protein signal transductionGO:0007265730.041
cellular ketone metabolic processGO:0042180800.040
multicellular organismal agingGO:001025930.040
regulation of cell cycle processGO:00105642660.039
chromatin modificationGO:00165682980.039
protein processingGO:00164852260.038
cellular component morphogenesisGO:00329893140.037
determination of adult lifespanGO:000834020.037
purine nucleoside triphosphate metabolic processGO:00091444120.037
nucleotide catabolic processGO:00091664080.037
chromatin organizationGO:00063253510.036
cell morphogenesisGO:00009022960.036
regulation of mitotic cell cycleGO:00073461890.035
positive regulation of phosphorylationGO:00423273940.035
purine nucleotide catabolic processGO:00061954050.035
negative regulation of phosphate metabolic processGO:00459362670.034
ribonucleoside triphosphate catabolic processGO:00092033910.034
regulation of transferase activityGO:00513383550.034
regulation of proteolysisGO:00301622930.034
nucleoside phosphate catabolic processGO:19012924120.034
oogenesisGO:004847720.033
organophosphate catabolic processGO:00464344300.033
regulation of cell cycle phase transitionGO:19019871260.033
negative regulation of phosphorus metabolic processGO:00105632670.032
regulation of protein maturationGO:19033171500.032
peripheral nervous system developmentGO:000742220.032
nervous system developmentGO:00073992930.031
positive regulation of cellular amino acid metabolic processGO:004576430.031
protein catabolic processGO:00301633250.031
mapk cascadeGO:00001652880.030
positive regulation of cellular component organizationGO:00511303760.030
regulation of anatomical structure morphogenesisGO:00226032860.030
cellular protein catabolic processGO:00442572610.030
ubiquitin dependent protein catabolic processGO:00065112060.030
signal transduction by phosphorylationGO:00230142970.030
ribonucleoside catabolic processGO:00424544060.030
purine ribonucleoside triphosphate metabolic processGO:00092054110.030
nucleoside triphosphate metabolic processGO:00091414220.030
purine ribonucleoside metabolic processGO:00461284370.030
vesicle mediated transportGO:00161923710.030
cell cycle checkpointGO:00000751170.029
purine ribonucleoside catabolic processGO:00461303980.029
purine containing compound catabolic processGO:00725234110.029
negative regulation of cell deathGO:00605483450.029
regulation of cellular ketone metabolic processGO:0010565500.029
purine nucleoside triphosphate catabolic processGO:00091463920.028
purine ribonucleotide catabolic processGO:00091544040.028
purine nucleoside catabolic processGO:00061523980.028
negative regulation of protein processingGO:00109551420.028
modification dependent macromolecule catabolic processGO:00436322120.028
posttranscriptional regulation of gene expressionGO:00106082130.028
positive regulation of catabolic processGO:00098963100.028
regulation of dna metabolic processGO:00510521530.028
covalent chromatin modificationGO:00165692540.028
nucleoside catabolic processGO:00091644080.027
ribonucleoside triphosphate metabolic processGO:00091994120.027
protein localization to organelleGO:00333652800.027
positive regulation of hydrolase activityGO:00513453310.027
somatic stem cell maintenanceGO:003501940.027
response to abiotic stimulusGO:00096283360.027
regulation of protein processingGO:00706131500.027
cell cycle g1 s phase transitionGO:0044843800.026
glycosyl compound catabolic processGO:19016584130.026
negative regulation of catalytic activityGO:00430863350.026
purine ribonucleoside triphosphate catabolic processGO:00092073910.026
negative regulation of protein maturationGO:19033181420.025
regulation of protein localizationGO:00328802960.025
cellular macromolecule catabolic processGO:00442653800.025
cell divisionGO:00513011680.025
regulation of kinase activityGO:00435493140.025
histone modificationGO:00165702510.024
cell developmentGO:00484683280.024
negative regulation of mitotic cell cycle phase transitionGO:1901991850.024
regulation of protein kinase activityGO:00458592890.024
proteolysis involved in cellular protein catabolic processGO:00516032440.023
negative regulation of cell differentiationGO:00455961710.023
maintenance of locationGO:00512351120.023
modification dependent protein catabolic processGO:00199412090.023
negative regulation of mitotic cell cycleGO:00459301020.023
regulation of mitotic cell cycle phase transitionGO:19019901180.023
carbohydrate derivative biosynthetic processGO:19011372070.023
small gtpase mediated signal transductionGO:0007264780.023
immune responseGO:00069553070.023
nucleoside triphosphate catabolic processGO:00091433940.022
dephosphorylationGO:00163112090.022
negative regulation of programmed cell deathGO:00430693210.022
segmentationGO:003528240.022
proteasome mediated ubiquitin dependent protein catabolic processGO:00431611560.022
ribonucleotide catabolic processGO:00092614050.022
negative regulation of cell cycle processGO:00109481210.022
response to oxygen containing compoundGO:19017003690.022
regulation of cellular component movementGO:00512703340.022
positive regulation of immune system processGO:00026842830.022
innate immune responseGO:00450871780.022
negative regulation of proteolysisGO:00458611320.022
chemical homeostasisGO:00488783060.022
negative regulation of protein modification processGO:00314002000.021
protein modification by small protein conjugationGO:00324463420.021
transmembrane transportGO:00550853990.021
positive regulation of apoptotic processGO:00430652460.021
anatomical structure formation involved in morphogenesisGO:00486462840.021
negative regulation of cell cycle phase transitionGO:1901988890.021
oocyte developmentGO:004859910.021
cellular response to endogenous stimulusGO:00714953360.021
negative regulation of phosphorylationGO:00423261740.021
cell projection organizationGO:00300302520.021
apoptotic signaling pathwayGO:00971902680.021
neuron fate commitmentGO:004866320.021
biological adhesionGO:00226103310.021
meiosis iGO:000712740.020
cation transportGO:00068123310.020
regulation of cellular response to stressGO:00801352440.020
positive regulation of programmed cell deathGO:00430682490.020
negative regulation of cell proliferationGO:00082852280.020
defense responseGO:00069523150.020
cell adhesionGO:00071553250.020
cytoplasmic transportGO:00164823790.020
lipid metabolic processGO:00066293810.020
ribonucleoside monophosphate catabolic processGO:00091581580.020
positive regulation of cellular catabolic processGO:00313312840.020
dna replicationGO:00062601160.020
positive regulation of organelle organizationGO:00106381950.020
regulation of mapk cascadeGO:00434082620.020
reproductive processGO:00224141060.020
negative regulation of intracellular signal transductionGO:19025321830.020
positive regulation of meiotic cell cycleGO:005144620.019
protein ubiquitinationGO:00165673140.019
positive regulation of cell cycleGO:00457871400.019
double strand break repairGO:00063021010.019
cell cycle arrestGO:0007050710.019
regulation of establishment of protein localizationGO:00702012420.019
positive regulation of cell deathGO:00109422630.019
regulation of protein transportGO:00512232130.019
positive regulation of cell cycle processGO:00900681060.019
regulation of cell divisionGO:00513021160.019
organelle fissionGO:00482851490.018
regulation of cellular protein catabolic processGO:1903362960.018
regulation of cell motilityGO:20001452990.018
positive regulation of protein phosphorylationGO:00019343130.018
immune system developmentGO:00025201950.018
morphogenesis of embryonic epitheliumGO:001633140.018
single organism cellular localizationGO:19025803320.018
response to growth factorGO:00708482050.017
mitotic cell cycle checkpointGO:0007093680.017
vasculature developmentGO:00019441810.017
transmembrane receptor protein tyrosine kinase signaling pathwayGO:00071691810.017
metal ion transportGO:00300012720.017
regulation of cell migrationGO:00303342890.017
regulation of nucleotide metabolic processGO:00061402690.017
regenerationGO:003109940.017
negative regulation of catabolic processGO:00098951040.017
negative regulation of multicellular organismal processGO:00512413170.017
positive regulation of developmental processGO:00510943140.017
oocyte differentiationGO:000999420.017
hindbrain developmentGO:003090230.017
negative regulation of cellular component organizationGO:00511292350.017
response to other organismGO:00517072610.017
wnt signaling pathwayGO:00160551560.017
regulation of dna replicationGO:0006275680.017
protein targetingGO:00066051870.017
neuromuscular junction developmentGO:000752830.017
cellular lipid metabolic processGO:00442553030.016
regulation of cytokine productionGO:00018172320.016
cytokinesisGO:0000910960.016
response to fungusGO:000962040.016
protein acetylationGO:00064731160.016
mitotic nuclear divisionGO:00070671190.016
response to cytokineGO:00340972320.016
generation of neuronsGO:00486991520.016
positive regulation of purine nucleotide metabolic processGO:19005442270.016
nucleocytoplasmic transportGO:00069131760.016
regulation of cell morphogenesisGO:00226041530.016
cellular response to growth factor stimulusGO:00713631970.016
negative regulation of transferase activityGO:00513481240.016
regulation of response to dna damage stimulusGO:2001020940.016
tube developmentGO:00352951250.016
response to external biotic stimulusGO:00432072610.016
epithelial cell proliferationGO:00506731280.016
neurogenesisGO:00220081690.015
rna processingGO:00063962550.015
positive regulation of cell differentiationGO:00455972110.015
regulation of nucleoside metabolic processGO:00091182090.015
circulatory system developmentGO:00723592620.015
negative regulation of cellular catabolic processGO:0031330830.015
regulation of purine nucleotide metabolic processGO:19005422640.015
regulation of proteasomal protein catabolic processGO:0061136870.015
positive regulation of transportGO:00510503360.015
reactive oxygen species metabolic processGO:0072593750.015
blood vessel developmentGO:00015681720.015
dna damage checkpointGO:0000077680.015
nucleoside monophosphate metabolic processGO:00091231910.015
negative regulation of apoptotic processGO:00430663160.015
organophosphate biosynthetic processGO:00904071630.015
intracellular protein transportGO:00068862700.015
nuclear divisionGO:00002801280.015
negative regulation of cellular amino acid metabolic processGO:004576320.015
regulation of intracellular protein transportGO:00331571230.015
response to hormoneGO:00097251750.015
neural tube formationGO:000184130.015
enzyme linked receptor protein signaling pathwayGO:00071673030.015
viral processGO:00160321460.014
locomotory behaviorGO:000762610.014
cellular response to external stimulusGO:00714961110.014
cellular response to abiotic stimulusGO:00712141170.014
nucleic acid phosphodiester bond hydrolysisGO:00903051020.014
organelle assemblyGO:00709251760.014
response to biotic stimulusGO:00096072760.014
positive regulation of mitotic cell cycleGO:0045931600.014
regulation of locomotionGO:00400123290.014
cellular response to cytokine stimulusGO:00713451810.014
membrane organizationGO:00610242920.014
internal peptidyl lysine acetylationGO:0018393970.014
negative regulation of protein catabolic processGO:0042177590.014
negative regulation of organelle organizationGO:00106391260.014
negative regulation of mitotic anaphase promoting complex activityGO:006056440.014
regulation of intracellular transportGO:00323861950.014
regulation of immune responseGO:00507762010.014
chromosome segregationGO:00070591140.014
regulation of proteasomal ubiquitin dependent protein catabolic processGO:0032434710.013
positive regulation of gtpase activityGO:00435471660.013
ion homeostasisGO:00508012300.013
regulation of nuclear divisionGO:0051783650.013
positive regulation of nucleotide catabolic processGO:00308131850.013
regulation of protein catabolic processGO:00421761550.013
secretionGO:00469032540.013
central nervous system developmentGO:00074171230.013
system processGO:00030083490.013
cellular response to oxygen containing compoundGO:19017012760.013
response to radiationGO:00093141510.013
hematopoietic or lymphoid organ developmentGO:00485341860.013
microtubule based processGO:00070172100.013
regulation of cytoplasmic transportGO:19036491490.013
histone acetylationGO:0016573930.013
regulation of endopeptidase activityGO:00525481700.013
atp metabolic processGO:00460341760.013
negative regulation of cellular amine metabolic processGO:003323930.013
regulation of gtpase activityGO:00430871800.013
nuclear transportGO:00511691790.013
regulation of reactive oxygen species metabolic processGO:2000377410.013
regulation of meiosisGO:004002030.013
spermatid developmentGO:000728640.013
regulation of chromosome organizationGO:00330441030.013
positive regulation of nucleotide metabolic processGO:00459812300.013
secretion by cellGO:00329402260.013
negative regulation of protein phosphorylationGO:00019331400.013
protein acylationGO:00435431380.013
epithelial cell differentiationGO:00308551410.012
compound eye developmentGO:004874910.012
gtp metabolic processGO:00460392390.012
response to organic cyclic compoundGO:00140702040.012
regulation of response to external stimulusGO:00321012220.012
jak stat cascadeGO:0007259460.012
dna integrity checkpointGO:0031570710.012
peptidyl lysine modificationGO:00182051440.012
proteasomal protein catabolic processGO:00104981760.012
regulation of sequence specific dna binding transcription factor activityGO:00510902110.012
negative regulation of hydrolase activityGO:00513461820.012
organ formationGO:004864530.012
memoryGO:000761330.012
ribonucleoside monophosphate metabolic processGO:00091611870.012
endocytosisGO:00068971590.012
positive regulation of immune responseGO:00507781590.012
negative regulation of transportGO:00510511760.012
positive regulation of kinase activityGO:00336742040.012
response to nitrogen compoundGO:19016981840.012
primary neural tube formationGO:001402030.012
regulation of epithelial cell proliferationGO:00506781130.012
cardiovascular system developmentGO:00723582620.012
purine ribonucleoside monophosphate metabolic processGO:00091671860.012
purine ribonucleoside monophosphate catabolic processGO:00091691580.012
regulation of purine nucleotide catabolic processGO:00331212050.012
establishment of protein localization to organelleGO:00725941720.012
single organism membrane organizationGO:00448022680.012
meiotic chromosome segregationGO:004513240.012
spermatid differentiationGO:004851540.011
monovalent inorganic cation transportGO:00156721280.011
brain developmentGO:0007420970.011
hemopoiesisGO:00300971800.011
rho protein signal transductionGO:0007266260.011
growthGO:00400072020.011
leukocyte activationGO:00453211640.011
neuroblast proliferationGO:000740540.011
regulation of secretion by cellGO:19035301770.011
cellular homeostasisGO:00197251960.011
blood vessel morphogenesisGO:00485141620.011
cell activationGO:00017752130.011
protein oligomerizationGO:00512591730.011
regulation of protein serine threonine kinase activityGO:00719001790.011
positive regulation of cellular component biogenesisGO:00440891580.011
cellular protein complex assemblyGO:00436231880.011
regulation of secretionGO:00510461940.011
positive regulation of purine nucleotide catabolic processGO:00331231850.011
autophagic cell deathGO:004810230.011
protein importGO:00170381300.011
regulation of proteolysis involved in cellular protein catabolic processGO:1903050910.011
response to bacteriumGO:00096171440.011
nitrogen compound transportGO:00717051910.011
regulation of nucleotide catabolic processGO:00308112050.011
organ morphogenesisGO:00098871470.011
embryo developmentGO:00097901230.011
cytokine productionGO:00018162470.011
regulation of cysteine type endopeptidase activityGO:20001161270.011
stem cell developmentGO:0048864690.011
single organism reproductive processGO:0044702980.011
intrinsic apoptotic signaling pathwayGO:00971931270.011
defense response to fungusGO:005083240.011
head developmentGO:00603221080.011
cell projection assemblyGO:00300311260.011
oocyte maturationGO:000155610.011
regulation of protein ubiquitinationGO:0031396950.011
regulation of neural precursor cell proliferationGO:200017740.011
regulation of ras protein signal transductionGO:00465781550.011
negative regulation of cellular protein catabolic processGO:1903363380.011
response to nutrient levelsGO:0031667810.011
organonitrogen compound biosynthetic processGO:19015662000.011
mitotic sister chromatid separationGO:0051306180.011
regulation of apoptotic signaling pathwayGO:20012331750.011
regulation of multi organism processGO:00439001570.011
mitotic sister chromatid segregationGO:0000070530.010
internal protein amino acid acetylationGO:00064751010.010
tube closureGO:006060630.010
response to lipidGO:00339932060.010
regulation of peptidase activityGO:00525471800.010
epithelium developmentGO:00604292270.010
viral life cycleGO:00190581320.010
regulation of dna repairGO:0006282470.010
cellular component disassemblyGO:0022411920.010
positive regulation of gtp catabolic processGO:00331261660.010
response to extracellular stimulusGO:0009991850.010
chromosome separationGO:0051304230.010
cellular response to extracellular stimulusGO:0031668720.010
embryonic epithelial tube formationGO:000183840.010
developmental process involved in reproductionGO:0003006660.010

NPAT disease predictions

DiseaseDO term IDSizeProbabilityFunc Analog Org
nervous system diseaseDOID:8634310.019
sensory system diseaseDOID:00501552030.019
disease of cellular proliferationDOID:145661740.018
central nervous system diseaseDOID:3311860.016
cancerDOID:1621670.014
organ system cancerDOID:00506861640.014
disease of metabolismDOID:00146672950.013
eye and adnexa diseaseDOID:14921500.012
eye diseaseDOID:56141490.012
neurodegenerative diseaseDOID:12891020.011