Homo sapiens

17 known processes

PLEKHA7

pleckstrin homology domain containing, family A member 7

(Aliases: DKFZp686M22243)

PLEKHA7 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
mesendoderm developmentGO:004838210.212
cardiac muscle cell cardiac muscle cell adhesionGO:008604210.207
catagenGO:004263730.182
negative regulation of catagenGO:005179610.099
cardiac muscle cell contractionGO:008600340.093
rho protein signal transductionGO:0007266260.082
small gtpase mediated signal transductionGO:0007264780.080
ras protein signal transductionGO:0007265730.080
cell junction maintenanceGO:003433140.075
glycosyl compound catabolic processGO:19016584130.071
cell adhesionGO:00071553250.069
purine nucleoside triphosphate metabolic processGO:00091444120.067
organophosphate catabolic processGO:00464344300.067
nucleoside phosphate catabolic processGO:19012924120.062
purine nucleotide catabolic processGO:00061954050.060
post embryonic developmentGO:000979120.060
calcium dependent cell cell adhesion via plasma membrane cell adhesion moleculesGO:001633920.060
nucleoside triphosphate catabolic processGO:00091433940.059
pituitary gland developmentGO:002198320.059
purine ribonucleoside metabolic processGO:00461284370.058
nucleoside triphosphate metabolic processGO:00091414220.055
purine nucleoside triphosphate catabolic processGO:00091463920.055
ribonucleoside triphosphate metabolic processGO:00091994120.054
positive regulation of keratinocyte proliferationGO:001083840.054
purine ribonucleoside catabolic processGO:00461303980.054
purine ribonucleotide catabolic processGO:00091544040.054
nucleotide catabolic processGO:00091664080.053
keratinizationGO:003142420.053
biological adhesionGO:00226103310.053
purine nucleoside catabolic processGO:00061523980.052
purine containing compound catabolic processGO:00725234110.052
purine ribonucleoside triphosphate metabolic processGO:00092054110.051
ribonucleoside triphosphate catabolic processGO:00092033910.051
gtp metabolic processGO:00460392390.050
ribonucleotide catabolic processGO:00092614050.050
positive regulation of catabolic processGO:00098963100.049
guanosine containing compound catabolic processGO:19010692390.049
actin filament based movementGO:0030048170.047
salivary gland morphogenesisGO:000743540.047
guanosine containing compound metabolic processGO:19010682440.047
ribonucleoside catabolic processGO:00424544060.046
system processGO:00030083490.046
regulation of gtpase activityGO:00430871800.045
embryonic epithelial tube formationGO:000183840.045
purine ribonucleoside triphosphate catabolic processGO:00092073910.044
morphogenesis of a polarized epitheliumGO:000173830.043
regulation of nucleoside metabolic processGO:00091182090.043
regulation of nucleotide metabolic processGO:00061402690.042
locomotory behaviorGO:000762610.042
negative regulation of hair cycleGO:004263620.042
cellular amino acid metabolic processGO:00065201160.041
actin mediated cell contractionGO:0070252120.041
positive regulation of cellular amine metabolic processGO:003324070.040
positive regulation of gtpase activityGO:00435471660.040
actin filament based processGO:00300292240.040
single organism cellular localizationGO:19025803320.039
positive regulation of hydrolase activityGO:00513453310.039
positive regulation of insulin like growth factor receptor signaling pathwayGO:004356840.039
positive regulation of purine nucleotide catabolic processGO:00331231850.039
membrane organizationGO:00610242920.038
secondary metabolite biosynthetic processGO:004455020.037
regulation of cell differentiationGO:00455953930.037
regulation of gtp catabolic processGO:00331241800.037
positive regulation of purine nucleotide metabolic processGO:19005442270.036
positive regulation of cellular amino acid metabolic processGO:004576430.036
positive regulation of gtp catabolic processGO:00331261660.036
regulation of cytoskeleton organizationGO:00514931770.036
morphogenesis of embryonic epitheliumGO:001633140.036
transmembrane transportGO:00550853990.036
regulation of ras gtpase activityGO:00323181280.036
amine metabolic processGO:0009308440.036
nervous system developmentGO:00073992930.036
single organism membrane organizationGO:00448022680.035
regulation of cellular amino acid metabolic processGO:000652160.035
multicellular organismal agingGO:001025930.035
cellular amine metabolic processGO:0044106410.035
regulation of cellular amine metabolic processGO:0033238110.035
nucleoside catabolic processGO:00091644080.035
positive regulation of cellular catabolic processGO:00313312840.035
branching involved in salivary gland morphogenesisGO:006044510.035
regulation of purine nucleotide catabolic processGO:00331212050.035
regulation of neuron migrationGO:200122230.034
endomembrane system organizationGO:00102561960.034
positive regulation of nucleotide catabolic processGO:00308131850.034
cytoplasmic transportGO:00164823790.034
regulation of cell cycleGO:00517263930.034
dephosphorylationGO:00163112090.034
determination of adult lifespanGO:000834020.033
single organism cell adhesionGO:00986021790.033
regulation of protein localizationGO:00328802960.032
regulation of purine nucleotide metabolic processGO:19005422640.032
positive regulation of transportGO:00510503360.032
regulation of ras protein signal transductionGO:00465781550.032
regulation of nucleotide catabolic processGO:00308112050.032
negative regulation of cellular protein metabolic processGO:00322693530.032
neural tube formationGO:000184130.031
negative regulation of multicellular organismal processGO:00512413170.031
regulation of transferase activityGO:00513383550.031
positive regulation of nucleotide metabolic processGO:00459812300.030
epithelium developmentGO:00604292270.030
cellular lipid metabolic processGO:00442553030.030
regulation of small gtpase mediated signal transductionGO:00510561560.029
ectoderm developmentGO:000739830.029
segmentationGO:003528240.029
establishment of protein localization to membraneGO:00901501210.029
positive regulation of nucleoside metabolic processGO:00459791860.029
muscle system processGO:0003012810.028
negative regulation of developmental processGO:00510932470.028
regulation of melanosome transportGO:190290810.028
cell morphogenesisGO:00009022960.028
regulation of hair follicle maturationGO:004881930.028
memoryGO:000761330.028
low density lipoprotein particle mediated signalingGO:005509610.027
regulation of cellular component movementGO:00512703340.027
single organismal cell cell adhesionGO:00163371480.027
gastrulation with mouth forming secondGO:000170210.027
regulation of proteolysisGO:00301622930.027
cell migration involved in gastrulationGO:004207410.027
regulation of cardiac muscle contractionGO:0055117330.026
regulation of protein kinase activityGO:00458592890.026
lipid metabolic processGO:00066293810.026
response to abiotic stimulusGO:00096283360.026
positive regulation of protein phosphorylationGO:00019343130.026
female gamete generationGO:000729220.026
cellular component morphogenesisGO:00329893140.026
ion transmembrane transportGO:00342203380.026
striated muscle contractionGO:0006941520.026
organic hydroxy compound metabolic processGO:19016151470.026
regulation of cellular ketone metabolic processGO:0010565500.026
microtubule cytoskeleton organizationGO:00002261760.025
protein localization to membraneGO:00726571600.025
oogenesisGO:004847720.025
negative regulation of phosphate metabolic processGO:00459362670.025
positive regulation of cell deathGO:00109422630.025
microtubule based processGO:00070172100.025
defense responseGO:00069523150.025
positive regulation of ras gtpase activityGO:00323201170.025
cellular ketone metabolic processGO:0042180800.024
neuromuscular junction developmentGO:000752830.024
positive regulation of cellular component organizationGO:00511303760.024
vesicle mediated transportGO:00161923710.024
regulation of actin filament based processGO:00329701410.024
cell junction organizationGO:0034330790.024
immune responseGO:00069553070.023
apoptotic signaling pathwayGO:00971902680.023
response to oxygen containing compoundGO:19017003690.023
muscle contractionGO:0006936730.023
chemical homeostasisGO:00488783060.023
protein localization to plasma membraneGO:0072659930.023
regulation of muscle system processGO:0090257530.023
regulation of melanin biosynthetic processGO:004802110.023
negative regulation of hydrolase activityGO:00513461820.023
regulation of cell motilityGO:20001452990.023
negative regulation of phosphorus metabolic processGO:00105632670.023
negative regulation of catalytic activityGO:00430863350.023
innate immune responseGO:00450871780.022
protein catabolic processGO:00301633250.022
cellular macromolecule catabolic processGO:00442653800.022
regulation of wnt signaling pathwayGO:00301111230.022
regulation of catagenGO:005179430.022
motor neuron axon guidanceGO:000804520.022
regulation of establishment of protein localizationGO:00702012420.022
response to low density lipoprotein particleGO:005509840.022
positive regulation of transferase activityGO:00513472270.022
negative regulation of protein modification processGO:00314002000.022
neurological system processGO:00508771630.022
cell projection organizationGO:00300302520.021
blastoderm segmentationGO:000735020.021
plasma membrane organizationGO:00070091150.021
regulation of peptidase activityGO:00525471800.021
regulation of anatomical structure morphogenesisGO:00226032860.021
cellular response to endogenous stimulusGO:00714953360.021
regulation of response to external stimulusGO:00321012220.021
small molecule biosynthetic processGO:00442831570.021
posttranscriptional regulation of gene expressionGO:00106082130.021
actin cytoskeleton organizationGO:00300362070.021
gtp catabolic processGO:00061842370.021
cardiovascular system developmentGO:00723582620.021
negative regulation of protein metabolic processGO:00512483910.021
negative regulation of apoptotic processGO:00430663160.020
lipoprotein particle mediated signalingGO:005509510.020
wnt signaling pathwayGO:00160551560.020
regulation of protein transportGO:00512232130.020
mitotic cell cycle processGO:19030472860.020
negative regulation of transforming growth factor beta2 productionGO:003291220.020
protein localization to organelleGO:00333652800.020
canonical wnt signaling pathwayGO:00600701160.020
neuroblast proliferationGO:000740540.020
positive regulation of programmed cell deathGO:00430682490.019
oxidation reduction processGO:00551143960.019
anion transportGO:00068201610.019
cellular protein catabolic processGO:00442572610.019
protein ubiquitinationGO:00165673140.019
positive regulation of phosphorylationGO:00423273940.019
cell developmentGO:00484683280.019
positive regulation of protein kinase activityGO:00458601900.019
negative regulation of cell differentiationGO:00455961710.019
regulation of endopeptidase activityGO:00525481700.019
intracellular protein transportGO:00068862700.019
protein oligomerizationGO:00512591730.019
metal ion transportGO:00300012720.018
maintenance of locationGO:00512351120.018
negative regulation of wnt signaling pathwayGO:0030178690.018
cardiac muscle cell action potential involved in contractionGO:0086002210.018
regulation of cell adhesionGO:00301551660.018
mitotic cell cycleGO:00002783260.018
protein maturationGO:00516042330.018
organelle assemblyGO:00709251760.018
cation transmembrane transportGO:00986552380.018
epithelial cell differentiationGO:00308551410.018
positive regulation of cell migrationGO:00303351720.018
nuclear transportGO:00511691790.018
inorganic ion transmembrane transportGO:00986602310.018
regulation of rho gtpase activityGO:0032319660.018
positive regulation of rho gtpase activityGO:0032321560.018
carbohydrate derivative biosynthetic processGO:19011372070.018
cellular macromolecular complex assemblyGO:00346223240.018
cell projection assemblyGO:00300311260.018
protein targetingGO:00066051870.017
monocarboxylic acid metabolic processGO:00327871850.017
regulation of cellular response to stressGO:00801352440.017
inner ear morphogenesisGO:004247240.017
hair follicle maturationGO:004882030.017
cardiac muscle contractionGO:0060048340.017
epithelial tube branching involved in lung morphogenesisGO:006044140.017
neurotransmitter secretionGO:000726940.017
spermatid differentiationGO:004851540.017
anterior posterior axis specificationGO:000994820.017
oocyte differentiationGO:000999420.017
proteolysis involved in cellular protein catabolic processGO:00516032440.017
positive regulation of cellular component movementGO:00512721810.017
cell substrate adhesionGO:00315891320.017
compound eye developmentGO:004874910.017
neurogenesisGO:00220081690.017
signal transduction by phosphorylationGO:00230142970.017
response to lithium ionGO:001022620.017
negative regulation of cellular component organizationGO:00511292350.017
oocyte developmentGO:004859910.017
anatomical structure formation involved in morphogenesisGO:00486462840.016
negative regulation of cell proliferationGO:00082852280.016
desmosome assemblyGO:000215940.016
regulation of cell cycle processGO:00105642660.016
cardiac muscle cell action potentialGO:0086001230.016
cytokine productionGO:00018162470.016
cation homeostasisGO:00550801890.016
regulation of canonical wnt signaling pathwayGO:0060828880.016
negative regulation of transcription from rna polymerase ii promoterGO:00001222810.016
regulation of cellular component biogenesisGO:00440872810.016
negative regulation of canonical wnt signaling pathwayGO:0090090550.016
vasculature developmentGO:00019441810.016
regulation of cell morphogenesisGO:00226041530.016
lipid biosynthetic processGO:00086101770.016
cell matrix adhesionGO:0007160850.016
reactive nitrogen species metabolic processGO:200105730.016
regulation of synaptic plasticityGO:004816730.016
adult locomotory behaviorGO:000834410.016
cell growthGO:00160491600.016
cation transportGO:00068123310.016
ameboidal type cell migrationGO:00016671350.016
protein processingGO:00164852260.016
reactive oxygen species biosynthetic processGO:190340940.016
matingGO:000761810.016
cellular protein complex assemblyGO:00436231880.016
negative regulation of intracellular signal transductionGO:19025321830.016
regulation of membrane potentialGO:0042391950.016
inorganic cation transmembrane transportGO:00986621940.016
tripartite regional subdivisionGO:000735120.016
cytokinesisGO:0000910960.016
regulation of immune responseGO:00507762010.016
regulation of sequence specific dna binding transcription factor activityGO:00510902110.016
mapk cascadeGO:00001652880.015
limbic system developmentGO:002176130.015
cell activationGO:00017752130.015
carbohydrate metabolic processGO:00059752070.015
organonitrogen compound biosynthetic processGO:19015662000.015
establishment of protein localization to organelleGO:00725941720.015
negative regulation of programmed cell deathGO:00430693210.015
circulatory system developmentGO:00723592620.015
regulation of cell developmentGO:00602841610.015
cell cell signalingGO:00072671550.015
blood vessel morphogenesisGO:00485141620.015
nucleocytoplasmic transportGO:00069131760.015
response to inorganic substanceGO:00100351270.015
response to growth factorGO:00708482050.015
positive regulation of developmental processGO:00510943140.015
negative regulation of cellular amino acid metabolic processGO:004576320.015
water homeostasisGO:0030104140.015
secretion by cellGO:00329402260.015
histone modificationGO:00165702510.015
regulation of apoptotic signaling pathwayGO:20012331750.015
regulation of rho protein signal transductionGO:0035023790.015
single organism carbohydrate metabolic processGO:00447231930.015
nitrogen compound transportGO:00717051910.015
cellular response to dna damage stimulusGO:00069743790.015
positive regulation of cell cycleGO:00457871400.015
chemotaxisGO:00069351570.015
glycoprotein biosynthetic processGO:0009101910.015
positive regulation of synaptic transmissionGO:005080640.015
positive regulation of protein transportGO:00512221350.014
regulation of cytokine productionGO:00018172320.014
organ formationGO:004864530.014
multicellular organismal signalingGO:0035637340.014
negative regulation of cellular amine metabolic processGO:003323930.014
regulation of secretionGO:00510461940.014
ribonucleoside monophosphate metabolic processGO:00091611870.014
rhythmic behaviorGO:000762220.014
anterior posterior axis specification embryoGO:000859520.014
reactive oxygen species metabolic processGO:0072593750.014
chromatin organizationGO:00063253510.014
circulatory system processGO:00030131130.014
regulation of protein stabilityGO:0031647870.014
response to other organismGO:00517072610.014
positive regulation of cellular component biogenesisGO:00440891580.014
response to organic cyclic compoundGO:00140702040.014
regulation of system processGO:00440571010.014
organophosphate biosynthetic processGO:00904071630.014
response to external biotic stimulusGO:00432072610.014
cell cycle phase transitionGO:00447701730.014
photoreceptor cell differentiationGO:004653020.014
establishment of protein localization to plasma membraneGO:0090002680.014
regulation of locomotionGO:00400123290.014
organic hydroxy compound biosynthetic processGO:1901617710.014
cochlea developmentGO:009010210.014
response to nitrogen compoundGO:19016981840.014
cell divisionGO:00513011680.014
regulation of heart rateGO:0002027380.014
cellular response to cytokine stimulusGO:00713451810.014
nerve developmentGO:002167540.014
associative learningGO:000830610.014
purine nucleoside monophosphate metabolic processGO:00091261860.014
positive regulation of cell proliferationGO:00082843010.014
regulation of striated muscle contractionGO:0006942370.014
regulation of cysteine type endopeptidase activity involved in apoptotic processGO:00432811160.014
response to organonitrogen compoundGO:00102431560.014
regulation of protein serine threonine kinase activityGO:00719001790.014
protein modification by small protein conjugationGO:00324463420.014
blastocyst developmentGO:000182430.014
regulation of reactive oxygen species biosynthetic processGO:190342630.014
endosomal transportGO:00161971290.014
epithelium migrationGO:00901321190.014
purine ribonucleoside monophosphate metabolic processGO:00091671860.014
regulation of kinase activityGO:00435493140.014
sensory perceptionGO:00076001030.014
ion homeostasisGO:00508012300.014
nucleoside monophosphate metabolic processGO:00091231910.013
spermatid developmentGO:000728640.013
regulation of intracellular protein transportGO:00331571230.013
regulation of protein complex assemblyGO:00432541470.013
rac protein signal transductionGO:0016601120.013
regulation of vesicle mediated transportGO:00606271300.013
chromatin modificationGO:00165682980.013
negative regulation of transportGO:00510511760.013
blood vessel developmentGO:00015681720.013
negative regulation of hair follicle developmentGO:005179910.013
peripheral nervous system developmentGO:000742220.013
peptidyl tyrosine phosphorylationGO:00181081700.013
response to lipidGO:00339932060.013
regulation of growthGO:00400081650.013
regulation of cell migrationGO:00303342890.013
carboxylic acid biosynthetic processGO:0046394970.013
regulation of i kappab kinase nf kappab signalingGO:00431221620.013
protein dephosphorylationGO:0006470810.013
protein homooligomerizationGO:00512601000.013
negative regulation of protein maturationGO:19033181420.013
regulation of cysteine type endopeptidase activityGO:20001161270.013
action potentialGO:0001508340.013
tissue migrationGO:00901301190.013
regulation of actin cytoskeleton organizationGO:00329561160.013
primary neural tube formationGO:001402030.013
release of cytoplasmic sequestered nf kappabGO:000858840.013
mitochondrion organizationGO:00070051560.013
modification dependent macromolecule catabolic processGO:00436322120.013
establishment or maintenance of bipolar cell polarityGO:006124520.013
neuron differentiationGO:00301821380.013
rna processingGO:00063962550.013
regulation of protein maturationGO:19033171500.013
negative regulation of cell deathGO:00605483450.013
proteasomal protein catabolic processGO:00104981760.013
regulation of cell substrate adhesionGO:0010810680.013
neural tube closureGO:000184330.013
ubiquitin dependent protein catabolic processGO:00065112060.013
regulation of protein catabolic processGO:00421761550.013
trophectodermal cell differentiationGO:000182930.013
negative regulation of cell motilityGO:20001461040.013
epithelial cell proliferationGO:00506731280.013
cellular response to growth factor stimulusGO:00713631970.013
response to cytokineGO:00340972320.013
i kappab kinase nf kappab signalingGO:00072491660.013
sex determinationGO:000753030.013
positive regulation of organelle organizationGO:00106381950.013
secretionGO:00469032540.013
syncytium formation by plasma membrane fusionGO:000076820.013
organic acid biosynthetic processGO:0016053970.013
activation of immune responseGO:00022531140.013
cell fate determinationGO:000170930.013
regulation of phosphatase activityGO:0010921810.013
response to biotic stimulusGO:00096072760.013
post embryonic organ developmentGO:004856910.013
negative regulation of cellular component movementGO:00512711060.012
atp metabolic processGO:00460341760.012
wound healingGO:00420601150.012
regulation of mitotic cell cycleGO:00073461890.012
cell projection morphogenesisGO:00488581290.012
regenerationGO:003109940.012
rna interferenceGO:001624640.012
circadian behaviorGO:004851220.012
visual behaviorGO:000763220.012
positive regulation of reactive oxygen species biosynthetic processGO:190342820.012
nuclear importGO:00511701060.012
hair follicle morphogenesisGO:003106920.012
positive regulation of response to external stimulusGO:0032103880.012
regulation of intracellular transportGO:00323861950.012
sensory perception of painGO:001923340.012
actin filament organizationGO:00070151280.012
divalent inorganic cation transportGO:00725111580.012
negative regulation of phosphatase activityGO:0010923610.012
covalent chromatin modificationGO:00165692540.012
maintenance of protein locationGO:0045185570.012
cellular response to oxygen containing compoundGO:19017012760.012
metencephalon developmentGO:002203720.012
cellular response to nitrogen compoundGO:19016991440.012
regulation of cell projection organizationGO:00313441070.012
blood circulationGO:00080151130.012
tube closureGO:006060630.012
modification dependent protein catabolic processGO:00199412090.012
regulation of body fluid levelsGO:0050878990.012
epiboly involved in gastrulation with mouth forming secondGO:005511310.012
alcohol metabolic processGO:00060661140.012
regulation of defense responseGO:00313471540.012
single organism nuclear importGO:19025931040.012
neuron developmentGO:00486661130.012
regulation of protein processingGO:00706131500.012
rab protein signal transductionGO:003248240.012
establishment of planar polarityGO:000173630.012
keratinocyte differentiationGO:0030216360.012
regulation of branching involved in salivary gland morphogenesisGO:006069310.012
cellular response to organonitrogen compoundGO:00714171240.012
generation of neuronsGO:00486991520.012
response to fungusGO:000962040.012
glycoprotein metabolic processGO:00091001100.012
establishment or maintenance of apical basal cell polarityGO:003508820.012
transmembrane receptor protein tyrosine kinase signaling pathwayGO:00071691810.012
epidermal cell differentiationGO:0009913450.012
response to axon injuryGO:004867810.012
regulation of secondary metabolite biosynthetic processGO:190037610.012
negative regulation of protein processingGO:00109551420.012
stem cell divisionGO:001714520.012
heart processGO:0003015620.012
negative regulation of hair follicle maturationGO:004881710.012
regulation of meiotic cell cycleGO:005144540.012
startle responseGO:000196430.012
maintenance of location in cellGO:0051651620.011
spinal cord developmentGO:002151040.011
mitotic cell cycle phase transitionGO:00447721620.011
negative regulation of transforming growth factor beta productionGO:007163540.011
protein importGO:00170381300.011
cellular ion homeostasisGO:00068731680.011
multi organism cellular processGO:00447641560.011
tissue morphogenesisGO:0048729960.011
regulation of mapk cascadeGO:00434082620.011
positive regulation of cell adhesionGO:0045785840.011
epidermis developmentGO:0008544590.011
male genitalia developmentGO:003053910.011
regulation of cytoplasmic transportGO:19036491490.011
positive regulation of neural precursor cell proliferationGO:200017920.011
metal ion homeostasisGO:00550651690.011
somitogenesisGO:000175620.011
hindbrain developmentGO:003090230.011
monovalent inorganic cation transportGO:00156721280.011
regulation of neural precursor cell proliferationGO:200017740.011

PLEKHA7 disease predictions

DiseaseDO term IDSizeProbabilityFunc Analog Org
musculoskeletal system diseaseDOID:172230.037
disease of cellular proliferationDOID:145661740.035
cancerDOID:1621670.035
organ system cancerDOID:00506861640.031
nervous system diseaseDOID:8634310.029
sensory system diseaseDOID:00501552030.029
inherited metabolic disorderDOID:6552420.024
disease of metabolismDOID:00146672950.024
central nervous system diseaseDOID:3311860.020
muscular diseaseDOID:00800001140.018
eye and adnexa diseaseDOID:14921500.018
eye diseaseDOID:56141490.018
muscle tissue diseaseDOID:661130.017
connective tissue diseaseDOID:651090.017
bone diseaseDOID:0080001880.015
immune system diseaseDOID:29141550.014
retinal diseaseDOID:56791180.014
gastrointestinal system cancerDOID:3119520.014
cardiovascular system diseaseDOID:12871060.014
reproductive organ cancerDOID:193230.013
neurodegenerative diseaseDOID:12891020.012
brain diseaseDOID:936730.012
myopathyDOID:4231040.012