| modification dependent macromolecule catabolic process | GO:0043632 | 212 | 0.246 | |
| proteasome mediated ubiquitin dependent protein catabolic process | GO:0043161 | 156 | 0.179 | |
| transmembrane transport | GO:0055085 | 399 | 0.159 | |
| modification dependent protein catabolic process | GO:0019941 | 209 | 0.117 | |
| protein catabolic process | GO:0030163 | 325 | 0.112 | |
| cellular protein catabolic process | GO:0044257 | 261 | 0.112 | |
| ubiquitin dependent protein catabolic process | GO:0006511 | 206 | 0.101 | |
| ion transmembrane transport | GO:0034220 | 338 | 0.099 | |
| response to endoplasmic reticulum stress | GO:0034976 | 49 | 0.097 | Zebrafish |
| protein localization to endoplasmic reticulum | GO:0070972 | 19 | 0.081 | |
| carbohydrate derivative biosynthetic process | GO:1901137 | 207 | 0.079 | |
| cellular macromolecule catabolic process | GO:0044265 | 380 | 0.078 | |
| protein localization to membrane | GO:0072657 | 160 | 0.074 | |
| metal ion transport | GO:0030001 | 272 | 0.072 | |
| protein modification by small protein conjugation | GO:0032446 | 342 | 0.071 | |
| cellular amino acid metabolic process | GO:0006520 | 116 | 0.070 | |
| protein ubiquitination | GO:0016567 | 314 | 0.069 | |
| glycoprotein metabolic process | GO:0009100 | 110 | 0.062 | |
| cellular divalent inorganic cation homeostasis | GO:0072503 | 128 | 0.060 | |
| maintenance of location | GO:0051235 | 112 | 0.058 | |
| lipid localization | GO:0010876 | 106 | 0.055 | |
| cellular homeostasis | GO:0019725 | 196 | 0.055 | |
| divalent inorganic cation homeostasis | GO:0072507 | 136 | 0.054 | |
| protein localization to organelle | GO:0033365 | 280 | 0.053 | |
| carbohydrate metabolic process | GO:0005975 | 207 | 0.051 | |
| purine nucleotide catabolic process | GO:0006195 | 405 | 0.050 | |
| glycoprotein biosynthetic process | GO:0009101 | 91 | 0.049 | |
| proteolysis involved in cellular protein catabolic process | GO:0051603 | 244 | 0.048 | |
| regulation of proteolysis | GO:0030162 | 293 | 0.047 | |
| inorganic ion transmembrane transport | GO:0098660 | 231 | 0.047 | |
| proteasomal protein catabolic process | GO:0010498 | 176 | 0.042 | |
| ion homeostasis | GO:0050801 | 230 | 0.041 | |
| apoptotic signaling pathway | GO:0097190 | 268 | 0.041 | |
| regulation of cellular amine metabolic process | GO:0033238 | 11 | 0.040 | |
| establishment of protein localization to membrane | GO:0090150 | 121 | 0.040 | |
| embryonic epithelial tube formation | GO:0001838 | 4 | 0.040 | |
| cation homeostasis | GO:0055080 | 189 | 0.040 | |
| response to biotic stimulus | GO:0009607 | 276 | 0.038 | |
| single organism cellular localization | GO:1902580 | 332 | 0.038 | |
| chemical homeostasis | GO:0048878 | 306 | 0.038 | |
| negative regulation of apoptotic process | GO:0043066 | 316 | 0.038 | |
| cytoplasmic transport | GO:0016482 | 379 | 0.037 | |
| determination of adult lifespan | GO:0008340 | 2 | 0.036 | |
| purine ribonucleoside triphosphate catabolic process | GO:0009207 | 391 | 0.036 | |
| nucleotide catabolic process | GO:0009166 | 408 | 0.036 | |
| glycosyl compound catabolic process | GO:1901658 | 413 | 0.036 | |
| regulation of cellular amino acid metabolic process | GO:0006521 | 6 | 0.035 | |
| post embryonic development | GO:0009791 | 2 | 0.035 | |
| innate immune response | GO:0045087 | 178 | 0.035 | |
| cellular metal ion homeostasis | GO:0006875 | 146 | 0.034 | |
| ribonucleotide catabolic process | GO:0009261 | 405 | 0.034 | |
| single organism membrane organization | GO:0044802 | 268 | 0.033 | |
| negative regulation of protein modification process | GO:0031400 | 200 | 0.033 | |
| negative regulation of cellular protein metabolic process | GO:0032269 | 353 | 0.033 | |
| cation transport | GO:0006812 | 331 | 0.033 | |
| divalent inorganic cation transport | GO:0072511 | 158 | 0.033 | |
| intracellular protein transport | GO:0006886 | 270 | 0.032 | |
| vesicle mediated transport | GO:0016192 | 371 | 0.032 | |
| nucleoside phosphate catabolic process | GO:1901292 | 412 | 0.031 | |
| system process | GO:0003008 | 349 | 0.031 | Zebrafish |
| purine nucleoside triphosphate metabolic process | GO:0009144 | 412 | 0.031 | |
| negative regulation of phosphorus metabolic process | GO:0010563 | 267 | 0.031 | |
| single organism carbohydrate metabolic process | GO:0044723 | 193 | 0.031 | |
| immune response | GO:0006955 | 307 | 0.031 | |
| nucleoside triphosphate catabolic process | GO:0009143 | 394 | 0.030 | |
| cellular cation homeostasis | GO:0030003 | 163 | 0.029 | |
| purine ribonucleoside catabolic process | GO:0046130 | 398 | 0.029 | |
| cellular amine metabolic process | GO:0044106 | 41 | 0.029 | |
| positive regulation of immune system process | GO:0002684 | 283 | 0.029 | |
| metal ion homeostasis | GO:0055065 | 169 | 0.029 | |
| ribonucleoside triphosphate metabolic process | GO:0009199 | 412 | 0.029 | |
| response to other organism | GO:0051707 | 261 | 0.028 | |
| osteoblast differentiation | GO:0001649 | 92 | 0.028 | |
| ribonucleoside catabolic process | GO:0042454 | 406 | 0.027 | |
| regulation of locomotion | GO:0040012 | 329 | 0.027 | |
| divalent metal ion transport | GO:0070838 | 152 | 0.026 | |
| positive regulation of cellular catabolic process | GO:0031331 | 284 | 0.026 | |
| ribonucleoside triphosphate catabolic process | GO:0009203 | 391 | 0.026 | |
| cellular lipid metabolic process | GO:0044255 | 303 | 0.026 | |
| nucleoside triphosphate metabolic process | GO:0009141 | 422 | 0.025 | |
| purine nucleoside catabolic process | GO:0006152 | 398 | 0.025 | |
| regulation of sequence specific dna binding transcription factor activity | GO:0051090 | 211 | 0.024 | |
| amine metabolic process | GO:0009308 | 44 | 0.024 | |
| cation transmembrane transport | GO:0098655 | 238 | 0.024 | |
| purine ribonucleoside metabolic process | GO:0046128 | 437 | 0.024 | |
| macromolecule glycosylation | GO:0043413 | 63 | 0.023 | |
| organonitrogen compound biosynthetic process | GO:1901566 | 200 | 0.023 | |
| regulation of anatomical structure morphogenesis | GO:0022603 | 286 | 0.023 | |
| regulation of protein localization | GO:0032880 | 296 | 0.022 | |
| protein targeting | GO:0006605 | 187 | 0.022 | |
| purine nucleoside triphosphate catabolic process | GO:0009146 | 392 | 0.022 | |
| negative regulation of hydrolase activity | GO:0051346 | 182 | 0.022 | |
| regulation of protein ubiquitination | GO:0031396 | 95 | 0.021 | |
| intrinsic apoptotic signaling pathway | GO:0097193 | 127 | 0.021 | |
| sequestering of metal ion | GO:0051238 | 24 | 0.021 | |
| negative regulation of cellular amine metabolic process | GO:0033239 | 3 | 0.021 | |
| cardiovascular system development | GO:0072358 | 262 | 0.021 | |
| negative regulation of catalytic activity | GO:0043086 | 335 | 0.021 | |
| defense response | GO:0006952 | 315 | 0.021 | |
| nitrogen compound transport | GO:0071705 | 191 | 0.020 | |
| cellular response to dna damage stimulus | GO:0006974 | 379 | 0.020 | |
| regulation of nucleotide metabolic process | GO:0006140 | 269 | 0.020 | |
| regulation of cellular component movement | GO:0051270 | 334 | 0.020 | |
| morphogenesis of embryonic epithelium | GO:0016331 | 4 | 0.020 | |
| cellular chemical homeostasis | GO:0055082 | 180 | 0.020 | |
| tissue morphogenesis | GO:0048729 | 96 | 0.020 | |
| nervous system development | GO:0007399 | 293 | 0.020 | Zebrafish |
| negative regulation of phosphate metabolic process | GO:0045936 | 267 | 0.020 | |
| response to external biotic stimulus | GO:0043207 | 261 | 0.019 | |
| regulation of transferase activity | GO:0051338 | 355 | 0.019 | |
| negative regulation of cellular amino acid metabolic process | GO:0045763 | 2 | 0.019 | |
| inorganic cation transmembrane transport | GO:0098662 | 194 | 0.019 | |
| nucleoside catabolic process | GO:0009164 | 408 | 0.019 | |
| regulation of protein modification by small protein conjugation or removal | GO:1903320 | 107 | 0.019 | |
| ossification | GO:0001503 | 121 | 0.019 | |
| regulation of cell motility | GO:2000145 | 299 | 0.018 | |
| glycosylation | GO:0070085 | 71 | 0.018 | |
| ameboidal type cell migration | GO:0001667 | 135 | 0.018 | |
| regulation of purine nucleotide catabolic process | GO:0033121 | 205 | 0.018 | |
| purine containing compound catabolic process | GO:0072523 | 411 | 0.018 | |
| regulation of cellular ketone metabolic process | GO:0010565 | 50 | 0.018 | |
| positive regulation of nucleoside metabolic process | GO:0045979 | 186 | 0.017 | |
| spermatid development | GO:0007286 | 4 | 0.017 | |
| regulation of cell migration | GO:0030334 | 289 | 0.017 | |
| protein glycosylation | GO:0006486 | 62 | 0.017 | |
| guanosine containing compound catabolic process | GO:1901069 | 239 | 0.017 | |
| multicellular organismal aging | GO:0010259 | 3 | 0.017 | Mouse |
| negative regulation of protein metabolic process | GO:0051248 | 391 | 0.017 | |
| cellular ion homeostasis | GO:0006873 | 168 | 0.016 | |
| gtp catabolic process | GO:0006184 | 237 | 0.016 | |
| regulation of kinase activity | GO:0043549 | 314 | 0.016 | |
| positive regulation of catabolic process | GO:0009896 | 310 | 0.016 | |
| regulation of gtpase activity | GO:0043087 | 180 | 0.016 | |
| locomotory behavior | GO:0007626 | 1 | 0.015 | |
| cellular response to lipid | GO:0071396 | 127 | 0.015 | |
| transition metal ion transport | GO:0000041 | 23 | 0.015 | |
| negative regulation of cell death | GO:0060548 | 345 | 0.015 | |
| dephosphorylation | GO:0016311 | 209 | 0.015 | |
| anion transport | GO:0006820 | 161 | 0.015 | |
| spermatid differentiation | GO:0048515 | 4 | 0.015 | |
| posttranscriptional regulation of gene expression | GO:0010608 | 213 | 0.015 | |
| cellular macromolecular complex assembly | GO:0034622 | 324 | 0.015 | |
| cellular ketone metabolic process | GO:0042180 | 80 | 0.015 | |
| biological adhesion | GO:0022610 | 331 | 0.015 | |
| positive regulation of purine nucleotide metabolic process | GO:1900544 | 227 | 0.015 | |
| nucleobase containing compound transport | GO:0015931 | 51 | 0.015 | |
| positive regulation of developmental process | GO:0051094 | 314 | 0.015 | |
| muscle cell fate commitment | GO:0042693 | 4 | 0.015 | |
| regulation of homeostatic process | GO:0032844 | 121 | 0.014 | |
| establishment of protein localization to organelle | GO:0072594 | 172 | 0.014 | |
| cell adhesion | GO:0007155 | 325 | 0.014 | |
| cellular calcium ion homeostasis | GO:0006874 | 117 | 0.014 | |
| endocytosis | GO:0006897 | 159 | 0.014 | |
| oxidation reduction process | GO:0055114 | 396 | 0.014 | |
| circulatory system development | GO:0072359 | 262 | 0.013 | |
| negative regulation of cellular component organization | GO:0051129 | 235 | 0.013 | |
| response to oxygen containing compound | GO:1901700 | 369 | 0.013 | |
| neuromuscular junction development | GO:0007528 | 3 | 0.013 | |
| segmentation | GO:0035282 | 4 | 0.013 | |
| positive regulation of cell proliferation | GO:0008284 | 301 | 0.013 | |
| positive regulation of cellular amine metabolic process | GO:0033240 | 7 | 0.013 | |
| mitotic cell cycle process | GO:1903047 | 286 | 0.013 | |
| calcium ion transport | GO:0006816 | 147 | 0.013 | |
| positive regulation of hydrolase activity | GO:0051345 | 331 | 0.013 | |
| purine ribonucleoside monophosphate metabolic process | GO:0009167 | 186 | 0.013 | |
| purine ribonucleotide catabolic process | GO:0009154 | 404 | 0.012 | |
| golgi vesicle transport | GO:0048193 | 80 | 0.012 | |
| regulation of cell differentiation | GO:0045595 | 393 | 0.012 | |
| regulation of protein kinase activity | GO:0045859 | 289 | 0.012 | |
| atp metabolic process | GO:0046034 | 176 | 0.012 | |
| nucleoside monophosphate catabolic process | GO:0009125 | 159 | 0.012 | |
| neurogenesis | GO:0022008 | 169 | 0.012 | |
| regulation of vasculature development | GO:1901342 | 97 | 0.012 | |
| positive regulation of nucleotide metabolic process | GO:0045981 | 230 | 0.012 | |
| rna interference | GO:0016246 | 4 | 0.012 | |
| reactive oxygen species metabolic process | GO:0072593 | 75 | 0.012 | |
| response to fungus | GO:0009620 | 4 | 0.012 | |
| membrane organization | GO:0061024 | 292 | 0.011 | |
| endomembrane system organization | GO:0010256 | 196 | 0.011 | |
| sequestering of calcium ion | GO:0051208 | 17 | 0.011 | |
| translation | GO:0006412 | 132 | 0.011 | |
| regulation of phosphatase activity | GO:0010921 | 81 | 0.011 | |
| positive regulation of purine nucleotide catabolic process | GO:0033123 | 185 | 0.011 | |
| metencephalon development | GO:0022037 | 2 | 0.011 | |
| receptor mediated endocytosis | GO:0006898 | 84 | 0.011 | |
| negative regulation of protein phosphorylation | GO:0001933 | 140 | 0.011 | |
| single organism cell adhesion | GO:0098602 | 179 | 0.011 | |
| positive regulation of protein phosphorylation | GO:0001934 | 313 | 0.011 | |
| calcium ion homeostasis | GO:0055074 | 122 | 0.011 | |
| regulation of proteolysis involved in cellular protein catabolic process | GO:1903050 | 91 | 0.011 | |
| regulation of cellular protein catabolic process | GO:1903362 | 96 | 0.011 | |
| negative regulation of phosphorylation | GO:0042326 | 174 | 0.011 | |
| regulation of protein catabolic process | GO:0042176 | 155 | 0.011 | |
| positive regulation of cellular amino acid metabolic process | GO:0045764 | 3 | 0.011 | |
| regulation of calcium ion transport | GO:0051924 | 79 | 0.011 | |
| cellular component morphogenesis | GO:0032989 | 314 | 0.011 | |
| cytosolic calcium ion homeostasis | GO:0051480 | 89 | 0.011 | |
| cell morphogenesis | GO:0000902 | 296 | 0.010 | |
| protein targeting to membrane | GO:0006612 | 42 | 0.010 | |
| positive regulation of phosphorylation | GO:0042327 | 394 | 0.010 | |
| regulation of immune response | GO:0050776 | 201 | 0.010 | |
| dna repair | GO:0006281 | 198 | 0.010 | |
| lipid metabolic process | GO:0006629 | 381 | 0.010 | |
| positive regulation of cell motility | GO:2000147 | 177 | 0.010 | |
| regulation of metal ion transport | GO:0010959 | 120 | 0.010 | |
| negative regulation of programmed cell death | GO:0043069 | 321 | 0.010 | |
| response to abiotic stimulus | GO:0009628 | 336 | 0.010 | |