Homo sapiens

141 known processes

FGD1

FYVE, RhoGEF and PH domain containing 1

(Aliases: MRXS16,ZFYVE3,FGDY,AAS)

FGD1 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
morphogenesis of embryonic epitheliumGO:001633140.170
cell morphogenesisGO:00009022960.165
Mouse
cell developmentGO:00484683280.151
cellular component morphogenesisGO:00329893140.131
Mouse
cranial nerve developmentGO:002154540.117
regulation of cellular component movementGO:00512703340.115
regulation of cell differentiationGO:00455953930.107
spinal cord developmentGO:002151040.104
nerve developmentGO:002167540.103
anatomical structure formation involved in morphogenesisGO:00486462840.099
cell adhesionGO:00071553250.099
cell projection organizationGO:00300302520.092
nervous system developmentGO:00073992930.091
organ morphogenesisGO:00098871470.090
regulation of anatomical structure morphogenesisGO:00226032860.089
Mouse
segmentationGO:003528240.087
circulatory system developmentGO:00723592620.086
epithelium developmentGO:00604292270.086
amine metabolic processGO:0009308440.085
female gamete generationGO:000729220.083
cell morphogenesis involved in differentiationGO:00009041440.080
retinal ganglion cell axon guidanceGO:003129020.080
post embryonic developmentGO:000979120.079
purine nucleoside catabolic processGO:00061523980.078
positive regulation of cellular component organizationGO:00511303760.078
purine ribonucleoside triphosphate catabolic processGO:00092073910.077
negative regulation of developmental processGO:00510932470.075
generation of neuronsGO:00486991520.074
positive regulation of developmental processGO:00510943140.073
oogenesisGO:004847720.073
cellular ketone metabolic processGO:0042180800.072
ribonucleoside triphosphate metabolic processGO:00091994120.072
glycosyl compound catabolic processGO:19016584130.070
biological adhesionGO:00226103310.068
regulation of cellular amine metabolic processGO:0033238110.067
ras protein signal transductionGO:0007265730.067
regulation of cell cycleGO:00517263930.065
regulation of cell migrationGO:00303342890.065
regulation of cellular ketone metabolic processGO:0010565500.064
motor neuron axon guidanceGO:000804520.064
purine containing compound catabolic processGO:00725234110.064
tissue morphogenesisGO:0048729960.063
ion transmembrane transportGO:00342203380.062
neuron differentiationGO:00301821380.061
actin filament based processGO:00300292240.061
neurogenesisGO:00220081690.059
cellular amino acid metabolic processGO:00065201160.059
taxisGO:00423301570.058
purine nucleoside triphosphate catabolic processGO:00091463920.058
regulation of cellular component biogenesisGO:00440872810.058
organophosphate catabolic processGO:00464344300.057
membrane organizationGO:00610242920.057
ribonucleoside catabolic processGO:00424544060.057
purine ribonucleoside metabolic processGO:00461284370.057
neuron projection developmentGO:00311751060.056
blastoderm segmentationGO:000735020.056
blood vessel morphogenesisGO:00485141620.054
regulation of nucleotide metabolic processGO:00061402690.054
transmembrane transportGO:00550853990.054
neuron developmentGO:00486661130.054
regulation of cellular amino acid metabolic processGO:000652160.054
skeletal system developmentGO:0001501790.053
embryonic epithelial tube formationGO:000183840.053
hindbrain developmentGO:003090230.053
negative regulation of cell differentiationGO:00455961710.052
regulation of locomotionGO:00400123290.052
inner ear morphogenesisGO:004247240.052
gtp metabolic processGO:00460392390.051
positive regulation of transportGO:00510503360.051
pituitary gland developmentGO:002198320.051
nucleotide catabolic processGO:00091664080.051
vasculature developmentGO:00019441810.051
cardiovascular system developmentGO:00723582620.050
mapk cascadeGO:00001652880.050
purine ribonucleoside triphosphate metabolic processGO:00092054110.050
positive regulation of phosphorylationGO:00423273940.050
ribonucleotide catabolic processGO:00092614050.049
negative regulation of multicellular organismal processGO:00512413170.049
regulation of cell growthGO:00015581350.049
tissue migrationGO:00901301190.049
nucleoside catabolic processGO:00091644080.049
cellular amine metabolic processGO:0044106410.049
positive regulation of cell differentiationGO:00455972110.049
nucleoside phosphate catabolic processGO:19012924120.048
guanosine containing compound catabolic processGO:19010692390.047
nucleoside triphosphate catabolic processGO:00091433940.047
small gtpase mediated signal transductionGO:0007264780.047
ribonucleoside triphosphate catabolic processGO:00092033910.047
neuron fate commitmentGO:004866320.046
positive regulation of cellular amino acid metabolic processGO:004576430.046
organ formationGO:004864530.046
positive regulation of protein phosphorylationGO:00019343130.045
single organism cellular localizationGO:19025803320.045
regulation of cell cycle processGO:00105642660.044
cellular response to endogenous stimulusGO:00714953360.044
positive regulation of cellular amine metabolic processGO:003324070.044
somatic stem cell maintenanceGO:003501940.043
positive regulation of catabolic processGO:00098963100.043
cell growthGO:00160491600.043
negative regulation of male gonad developmentGO:200001910.043
locomotory behaviorGO:000762610.042
head developmentGO:00603221080.041
blood vessel developmentGO:00015681720.041
rho protein signal transductionGO:0007266260.041
regulation of kinase activityGO:00435493140.041
epithelium migrationGO:00901321190.041
regulation of actin filament based processGO:00329701410.041
anterior posterior axis specificationGO:000994820.041
purine nucleoside triphosphate metabolic processGO:00091444120.041
embryonic morphogenesisGO:0048598850.041
purine ribonucleoside catabolic processGO:00461303980.041
embryonic camera type eye developmentGO:003107620.041
positive regulation of cellular component movementGO:00512721810.041
central nervous system developmentGO:00074171230.040
gtp catabolic processGO:00061842370.040
positive regulation of epithelial cell proliferation involved in wound healingGO:006005430.040
positive regulation of nucleotide metabolic processGO:00459812300.040
regulation of gtp catabolic processGO:00331241800.040
purine ribonucleotide catabolic processGO:00091544040.040
regulation of cell motilityGO:20001452990.040
positive regulation of cell proliferationGO:00082843010.039
ameboidal type cell migrationGO:00016671350.039
actin cytoskeleton organizationGO:00300362070.039
nucleoside triphosphate metabolic processGO:00091414220.039
cardiac muscle cell contractionGO:008600340.039
single organism membrane organizationGO:00448022680.039
regulation of purine nucleotide metabolic processGO:19005422640.039
epithelial cell differentiationGO:00308551410.039
positive regulation of locomotionGO:00400171860.039
single organism cell adhesionGO:00986021790.038
negative regulation of protein metabolic processGO:00512483910.038
cellular response to oxygen containing compoundGO:19017012760.038
forebrain regionalizationGO:002187130.038
neuromuscular junction developmentGO:000752830.038
multicellular organismal agingGO:001025930.038
non canonical wnt signaling pathway via mapk cascadeGO:003803040.038
regenerationGO:003109940.038
regulation of nucleoside metabolic processGO:00091182090.038
enzyme linked receptor protein signaling pathwayGO:00071673030.038
carbohydrate derivative biosynthetic processGO:19011372070.038
regulation of transferase activityGO:00513383550.038
protein localization to membraneGO:00726571600.037
positive regulation of hydrolase activityGO:00513453310.037
neural tube formationGO:000184130.037
epithelial cell migrationGO:00106311190.037
cell projection morphogenesisGO:00488581290.036
positive regulation of cell motilityGO:20001471770.036
canonical wnt signaling pathway involved in mesenchymal stem cell differentiationGO:004433820.036
brain developmentGO:0007420970.036
vesicle mediated transportGO:00161923710.036
cell cell signalingGO:00072671550.035
chemotaxisGO:00069351570.035
growthGO:00400072020.035
regulation of male gonad developmentGO:200001840.035
regulation of nervous system developmentGO:0051960880.035
positive regulation of cell deathGO:00109422630.035
negative regulation of cell proliferationGO:00082852280.034
regulation of mitotic cell cycleGO:00073461890.034
determination of adult lifespanGO:000834020.034
regulation of establishment of protein localizationGO:00702012420.034
response to growth factorGO:00708482050.034
regulation of purine nucleotide catabolic processGO:00331212050.034
morphogenesis of an epitheliumGO:0002009600.034
positive regulation of apoptotic processGO:00430652460.034
regulation of gtpase activityGO:00430871800.034
cell part morphogenesisGO:00329901370.033
sex determinationGO:000753030.033
canonical wnt signaling pathway involved in osteoblast differentiationGO:004433920.033
negative regulation of transcription from rna polymerase ii promoterGO:00001222810.033
endomembrane system organizationGO:00102561960.033
negative regulation of catalytic activityGO:00430863350.033
regulation of protein localizationGO:00328802960.032
guanosine containing compound metabolic processGO:19010682440.032
regulation of axon guidanceGO:190266730.032
regulation of cytoskeleton organizationGO:00514931770.032
transmembrane receptor protein tyrosine kinase signaling pathwayGO:00071691810.032
cartilage condensationGO:000150210.032
cell fate determinationGO:000170930.032
neuron projection regenerationGO:003110210.032
negative regulation of cellular protein metabolic processGO:00322693530.032
neurotransmitter secretionGO:000726940.032
wnt signaling pathwayGO:00160551560.032
negative regulation of axonogenesisGO:005077140.031
dermatome developmentGO:006105430.031
negative regulation of programmed cell deathGO:00430693210.031
cellular macromolecule catabolic processGO:00442653800.030
regulation of cell developmentGO:00602841610.030
system processGO:00030083490.030
forebrain generation of neuronsGO:002187230.030
tube morphogenesisGO:0035239950.030
negative regulation of cell cycleGO:00457861930.030
response to oxygen containing compoundGO:19017003690.030
limb bud formationGO:006017410.030
regulation of hormone levelsGO:00108171250.030
purine nucleotide catabolic processGO:00061954050.030
mesenchyme developmentGO:0060485590.030
cellular response to dna damage stimulusGO:00069743790.030
positive regulation of cell developmentGO:0010720920.030
mitotic cell cycle processGO:19030472860.030
canonical wnt signaling pathwayGO:00600701160.029
negative regulation of cell deathGO:00605483450.029
regulation of nucleotide catabolic processGO:00308112050.029
regulation of cell adhesionGO:00301551660.029
negative regulation of canonical wnt signaling pathwayGO:0090090550.029
mitotic cell cycleGO:00002783260.029
inorganic ion transmembrane transportGO:00986602310.029
cellular macromolecular complex assemblyGO:00346223240.029
positive regulation of nucleotide catabolic processGO:00308131850.029
wound healingGO:00420601150.029
cellular response to growth factor stimulusGO:00713631970.029
regulation of mapk cascadeGO:00434082620.029
cell substrate adhesionGO:00315891320.028
regulation of canonical wnt signaling pathwayGO:0060828880.028
cell matrix adhesionGO:0007160850.028
cloacal septationGO:006019710.028
positive regulation of aldosterone biosynthetic processGO:003234920.028
angiogenesisGO:00015251470.027
regulation of cell projection organizationGO:00313441070.027
cell differentiation in spinal cordGO:002151510.027
embryo developmentGO:00097901230.027
positive regulation of purine nucleotide catabolic processGO:00331231850.027
positive regulation of gtpase activityGO:00435471660.027
endodermal cell fate commitmentGO:000171140.027
regulation of cell morphogenesisGO:00226041530.027
Mouse
cytoplasmic transportGO:00164823790.026
metencephalon developmentGO:002203720.026
positive regulation of cell migrationGO:00303351720.026
tube developmentGO:00352951250.026
endothelial cell migrationGO:0043542860.026
intracellular protein transportGO:00068862700.026
negative regulation of wnt signaling pathwayGO:0030178690.026
forelimb morphogenesisGO:003513640.026
cranial nerve morphogenesisGO:002160210.026
posttranscriptional regulation of gene expressionGO:00106082130.026
oocyte developmentGO:004859910.026
regulation of cellular response to stressGO:00801352440.026
regulation of epithelial cell proliferationGO:00506781130.025
chromatin organizationGO:00063253510.025
establishment of protein localization to membraneGO:00901501210.025
signal transduction by phosphorylationGO:00230142970.025
response to woundingGO:00096111680.025
neuron projection morphogenesisGO:0048812500.025
positive regulation of cellular component biogenesisGO:00440891580.025
neuroblast proliferationGO:000740540.025
negative regulation of apoptotic processGO:00430663160.025
single organismal cell cell adhesionGO:00163371480.025
regulation of neurogenesisGO:0050767820.025
oocyte differentiationGO:000999420.025
cell cycle phase transitionGO:00447701730.025
positive regulation of gtp catabolic processGO:00331261660.025
embryonic forelimb morphogenesisGO:003511540.025
behaviorGO:00076101120.024
peripheral nervous system developmentGO:000742220.024
actin mediated cell contractionGO:0070252120.024
microtubule based processGO:00070172100.024
forebrain dorsal ventral pattern formationGO:002179810.024
morphogenesis of a polarized epitheliumGO:000173830.024
adult locomotory behaviorGO:000834410.024
peptidyl tyrosine modificationGO:00182121700.024
regulation of protein kinase activityGO:00458592890.023
anterior posterior axis specification embryoGO:000859520.023
nuclear transportGO:00511691790.023
positive regulation of purine nucleotide metabolic processGO:19005442270.023
regulation of intracellular transportGO:00323861950.023
regulation of neurotransmitter secretionGO:004692830.023
immune responseGO:00069553070.023
protein localization to organelleGO:00333652800.023
epithelial cell proliferationGO:00506731280.023
apoptotic signaling pathwayGO:00971902680.023
protein modification by small protein conjugationGO:00324463420.023
negative regulation of phosphorus metabolic processGO:00105632670.023
neural crest cell developmentGO:001403230.023
actin filament based movementGO:0030048170.023
positive regulation of protein kinase activityGO:00458601900.023
inorganic cation transmembrane transportGO:00986621940.022
response to abiotic stimulusGO:00096283360.022
renal system developmentGO:0072001630.022
regulation of ras protein signal transductionGO:00465781550.022
plasma membrane organizationGO:00070091150.022
organonitrogen compound biosynthetic processGO:19015662000.022
mitotic cell cycle phase transitionGO:00447721620.022
ossificationGO:00015031210.022
positive regulation of cellular catabolic processGO:00313312840.022
stem cell developmentGO:0048864690.022
somatic stem cell divisionGO:004810310.022
regulation of wnt signaling pathwayGO:00301111230.022
reproductive processGO:00224141060.022
negative regulation of cellular component organizationGO:00511292350.022
digestive system developmentGO:0055123750.022
osteoblast differentiationGO:0001649920.022
protein ubiquitinationGO:00165673140.022
axon cargo transportGO:000808820.021
negative regulation of locomotionGO:00400131180.021
compound eye developmentGO:004874910.021
protein catabolic processGO:00301633250.021
chromatin modificationGO:00165682980.021
ventral spinal cord developmentGO:002151710.021
positive regulation of programmed cell deathGO:00430682490.021
endochondral bone morphogenesisGO:006035030.021
regulation of growthGO:00400081650.021
negative regulation of cell growthGO:0030308830.021
negative regulation of phosphate metabolic processGO:00459362670.021
regulation of secretion by cellGO:19035301770.021
memoryGO:000761330.021
regulation of secretionGO:00510461940.021
epithelial tube morphogenesisGO:0060562380.021
tripartite regional subdivisionGO:000735120.021
positive regulation of transferase activityGO:00513472270.020
establishment of tissue polarityGO:000716430.020
cellular protein catabolic processGO:00442572610.020
glycoprotein metabolic processGO:00091001100.020
lipid metabolic processGO:00066293810.020
secretionGO:00469032540.020
regulation of cell cell adhesionGO:0022407570.020
microtubule cytoskeleton organizationGO:00002261760.020
positive regulation of nucleoside metabolic processGO:00459791860.020
regulation of cell substrate adhesionGO:0010810680.020
regulation of vesicle mediated transportGO:00606271300.020
cellular response to organic cyclic compoundGO:00714071270.020
digestive tract developmentGO:0048565750.020
regulation of peptidase activityGO:00525471800.020
primary neural tube formationGO:001402030.020
positive regulation of keratinocyte migrationGO:005154940.020
regionalizationGO:0003002290.020
positive regulation of secretionGO:00510471160.020
cardiac muscle contractionGO:0060048340.019
neurological system processGO:00508771630.019
cell morphogenesis involved in neuron differentiationGO:0048667440.019
striated muscle contractionGO:0006941520.019
connective tissue developmentGO:0061448390.019
cellular response to lipidGO:00713961270.019
histone modificationGO:00165702510.019
anion transportGO:00068201610.019
positive regulation of ras gtpase activityGO:00323201170.019
autonomic nervous system developmentGO:004848310.019
metal ion transportGO:00300012720.019
regulation of ras gtpase activityGO:00323181280.019
establishment or maintenance of apical basal cell polarityGO:003508820.019
startle responseGO:000196430.019
positive regulation of kinase activityGO:00336742040.019
regulation of protein complex assemblyGO:00432541470.019
regulation of dermatome developmentGO:006118330.019
stem cell differentiationGO:0048863930.019
limbic system developmentGO:002176130.019
regulation of neuron differentiationGO:0045664700.019
establishment of planar polarityGO:000173630.019
carbohydrate metabolic processGO:00059752070.019
tube closureGO:006060630.019
regulation of cell cycle phase transitionGO:19019871260.019
regulation of membrane potentialGO:0042391950.019
skeletal system morphogenesisGO:0048705240.019
reactive oxygen species metabolic processGO:0072593750.019
regulation of axon extension involved in axon guidanceGO:004884120.019
semaphorin plexin signaling pathwayGO:007152640.019
negative regulation of cell adhesionGO:0007162640.019
regulation of epithelial cell migrationGO:0010632930.018
cell projection assemblyGO:00300311260.018
dephosphorylationGO:00163112090.018
regulation of actin cytoskeleton organizationGO:00329561160.018
endodermal cell fate specificationGO:000171440.018
regulation of acrosome reactionGO:006004640.018
positive regulation of mapk cascadeGO:00434101900.018
regulation of response to external stimulusGO:00321012220.018
protein localization to plasma membraneGO:0072659930.018
regulation of protein serine threonine kinase activityGO:00719001790.018
regulation of protein transportGO:00512232130.018
single organism reproductive processGO:0044702980.018
protein targetingGO:00066051870.018
regulation of sequence specific dna binding transcription factor activityGO:00510902110.018
cell junction organizationGO:0034330790.018
negative regulation of cell migrationGO:00303361020.018
embryonic eye morphogenesisGO:004804820.018
regulation of reactive oxygen species metabolic processGO:2000377410.018
specification of organ identityGO:001009230.018
nitrogen compound transportGO:00717051910.018
cerebellum developmentGO:002154920.018
establishment or maintenance of bipolar cell polarityGO:006124520.018
glial cell migrationGO:000834740.018
regulation of keratinocyte migrationGO:005154740.018
negative regulation of hydrolase activityGO:00513461820.018
negative regulation of protein modification processGO:00314002000.018
cation transportGO:00068123310.018
positive regulation of cortisol biosynthetic processGO:200006610.018
mesonephric duct developmentGO:007217730.018
glycoprotein biosynthetic processGO:0009101910.018
negative regulation of growthGO:0045926970.018
regulation of neural precursor cell proliferationGO:200017740.018
protein autophosphorylationGO:00467771230.018
organelle assemblyGO:00709251760.017
regulation of neuron projection developmentGO:0010975570.017
negative regulation of cellular component movementGO:00512711060.017
positive regulation of steroid hormone biosynthetic processGO:009003120.017
oxidative stress induced premature senescenceGO:009040330.017
positive regulation of nervous system developmentGO:0051962540.017
stem cell divisionGO:001714520.017
proteolysis involved in cellular protein catabolic processGO:00516032440.017
cation transmembrane transportGO:00986552380.017
negative regulation of axon extensionGO:003051720.017
negative regulation of androgen biosynthetic processGO:200018010.017
prostate gland developmentGO:003085030.017
negative regulation of gliogenesisGO:001401430.017
digestive tract morphogenesisGO:0048546560.017
tongue developmentGO:004358610.017
single organism carbohydrate metabolic processGO:00447231930.017
regulation of intracellular protein transportGO:00331571230.017
cell aggregationGO:009874310.017
secretion by cellGO:00329402260.017
lens development in camera type eyeGO:000208820.017
establishment of protein localization to plasma membraneGO:0090002680.017
regulation of proteolysisGO:00301622930.017
axon developmentGO:0061564340.017
somitogenesisGO:000175620.016
cellular lipid metabolic processGO:00442553030.016
positive regulation of male gonad developmentGO:200002030.016
cerebral cortex cell migrationGO:002179530.016
positive regulation of hormone biosynthetic processGO:004688640.016
pattern specification processGO:0007389430.016
rhythmic behaviorGO:000762220.016
negative regulation of testosterone biosynthetic processGO:200022510.016
regulation of endopeptidase activityGO:00525481700.016
positive regulation of neuron differentiationGO:0045666400.016
embryonic digestive tract morphogenesisGO:004855720.016
spermatid differentiationGO:004851540.016
cell cell junction organizationGO:0045216690.016
regulation of bindingGO:00510981110.016
ectoderm developmentGO:000739830.016
negative regulation of transportGO:00510511760.016
neural tube closureGO:000184330.016
regulation of mitotic cell cycle phase transitionGO:19019901180.016
cell fate commitment involved in pattern specificationGO:006058110.016
covalent chromatin modificationGO:00165692540.016
axis elongationGO:000340140.016
neural tube patterningGO:002153220.016
chemical homeostasisGO:00488783060.016
syncytium formation by plasma membrane fusionGO:000076820.016
organophosphate biosynthetic processGO:00904071630.016
positive regulation of secretion by cellGO:19035321080.016
nucleocytoplasmic transportGO:00069131760.016
protein acylationGO:00435431380.016
establishment or maintenance of epithelial cell apical basal polarityGO:004519710.016
gamma aminobutyric acid signaling pathwayGO:000721430.015
maintenance of locationGO:00512351120.015
regulation of synaptic plasticityGO:004816730.015
testosterone biosynthetic processGO:006137020.015
circadian behaviorGO:004851220.015
negative regulation of cellular amino acid metabolic processGO:004576320.015
negative regulation of cell developmentGO:0010721480.015
modification dependent macromolecule catabolic processGO:00436322120.015
negative regulation of mitotic cell cycleGO:00459301020.015
cellular response to histamineGO:007142030.015
dna repairGO:00062811980.015
positive regulation of tooth mineralizationGO:007017220.015
negative regulation of testicular blood vessel morphogenesisGO:006136910.015
ion homeostasisGO:00508012300.015
mesenchymal cell differentiationGO:0048762520.015
forebrain neuron differentiationGO:002187930.015
regulation of cytoplasmic transportGO:19036491490.015
proteasomal protein catabolic processGO:00104981760.015
immune system developmentGO:00025201950.015
actin filament organizationGO:00070151280.015
androgen biosynthetic processGO:000670230.015
heart developmentGO:0007507950.015
cellular response to cytokine stimulusGO:00713451810.015
cellular chemical homeostasisGO:00550821800.015
muscle system processGO:0003012810.015
catagenGO:004263730.015
regulation of glial cell proliferationGO:006025140.015
myoblast fusionGO:000752010.015
response to lipidGO:00339932060.015
positive regulation of cell cycle processGO:00900681060.015
neuronal stem cell divisionGO:003644510.015
positive regulation of neural precursor cell proliferationGO:200017920.015
regulation of protein stabilityGO:0031647870.015
negative regulation of cellular amine metabolic processGO:003323930.015
rab protein signal transductionGO:003248240.015
salivary gland morphogenesisGO:000743540.015
muscle cell fate commitmentGO:004269340.014
negative regulation of intracellular signal transductionGO:19025321830.014

FGD1 disease predictions

DiseaseDO term IDSizeProbabilityFunc Analog Org
musculoskeletal system diseaseDOID:172230.036
disease of metabolismDOID:00146672950.033
inherited metabolic disorderDOID:6552420.025
nervous system diseaseDOID:8634310.023
Human
central nervous system diseaseDOID:3311860.023
sensory system diseaseDOID:00501552030.019
bone development diseaseDOID:0080006550.018
connective tissue diseaseDOID:651090.018
bone diseaseDOID:0080001880.018
disease of cellular proliferationDOID:145661740.016
cancerDOID:1621670.016
eye and adnexa diseaseDOID:14921500.016
organ system cancerDOID:00506861640.015
cardiovascular system diseaseDOID:12871060.015
eye diseaseDOID:56141490.015