Homo sapiens

115 known processes

UHRF1

ubiquitin-like with PHD and ring finger domains 1

(Aliases: MGC138707,ICBP90,RNF106,Np95,FLJ21925,hNP95)

UHRF1 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
methylation dependent chromatin silencingGO:000634631.000
chromatin organizationGO:00063253510.996
dna conformation changeGO:00711031130.994
histone h3 k9 modificationGO:0061647110.992
dna methylation or demethylationGO:0044728190.989
gene silencingGO:0016458490.982
histone lysine methylationGO:0034968500.981
chromatin modificationGO:00165682980.973
dna methylation on cytosineGO:003277630.971
negative regulation of chromosome organizationGO:2001251480.965
methylationGO:00322591060.961
protein alkylationGO:0008213740.948
dna modificationGO:0006304270.940
genetic imprintingGO:007151410.926
macromolecule methylationGO:0043414970.922
sulfur compound metabolic processGO:00067901010.916
chromatin silencingGO:0006342120.916
histone methylationGO:0016571600.913
regulation of gene expression epigeneticGO:0040029730.911
cellular modified amino acid metabolic processGO:0006575640.903
dna replication dependent nucleosome organizationGO:0034723320.903
histone h3 k4 methylationGO:0051568270.879
alpha amino acid metabolic processGO:1901605720.874
negative regulation of organelle organizationGO:00106391260.858
negative regulation of histone methylationGO:003106160.852
negative regulation of gene expression epigeneticGO:0045814190.835
nucleosome assemblyGO:0006334500.829
dna hypermethylationGO:004402610.827
histone h3 k9 methylationGO:0051567100.825
chromatin assemblyGO:0031497610.825
response to activityGO:001482300.799
negative regulation of histone h3 k9 methylationGO:005157330.789
cellular amino acid metabolic processGO:00065201160.752
positive regulation of histone h3 k4 methylationGO:005157180.735
protein methylationGO:0006479740.735
dna methylationGO:000630670.710
response to caffeineGO:003100030.704
histone modificationGO:00165702510.651
positive regulation of chromatin modificationGO:1903310300.645
response to oxygen levelsGO:00704821000.623
dna packagingGO:0006323770.604
negative regulation of cellular component organizationGO:00511292350.598
positive regulation of organelle organizationGO:00106381950.568
regulation of dna methylationGO:004403020.566
covalent chromatin modificationGO:00165692540.553
dna repairGO:00062811980.552
response to hypoxiaGO:0001666960.536
mitotic cell cycleGO:00002783260.536
retina layer formationGO:001084230.523
nucleosome organizationGO:0034728660.521
cellular response to endogenous stimulusGO:00714953360.514
response to decreased oxygen levelsGO:0036293960.500
regulation of gene expression by genetic imprintingGO:000634910.487
dna alkylationGO:000630570.487
positive regulation of chromosome organizationGO:2001252410.481
cellular response to amino acid stimulusGO:0071230120.474
positive regulation of cellular component organizationGO:00511303760.473
negative regulation of transcription from rna polymerase ii promoterGO:00001222810.471
negative regulation of protein metabolic processGO:00512483910.470
regulation of chromosome organizationGO:00330441030.466
response to radiationGO:00093141510.464
chromatin assembly or disassemblyGO:0006333780.464
regulation of dna metabolic processGO:00510521530.436
negative regulation of cellular protein metabolic processGO:00322693530.404
response to amino acidGO:0043200140.387
response to estrogenGO:0043627470.372
response to oxygen containing compoundGO:19017003690.358
cellular response to nitrogen compoundGO:19016991440.351
response to alkaloidGO:0043279200.349
cellular response to organonitrogen compoundGO:00714171240.349
positive regulation of histone methylationGO:0031062120.344
regulation of chromatin organizationGO:1902275560.336
cellular response to acid chemicalGO:0071229440.336
response to drugGO:0042493810.334
response to organonitrogen compoundGO:00102431560.333
negative regulation of histone modificationGO:0031057190.331
cellular macromolecular complex assemblyGO:00346223240.329
response to hyperoxiaGO:005509340.326
mitotic cell cycle processGO:19030472860.326
negative regulation of chromatin modificationGO:1903309210.325
response to estradiolGO:0032355230.323
response to toxic substanceGO:0009636370.321
response to nitrogen compoundGO:19016981840.319
purine ribonucleoside metabolic processGO:00461284370.313
cellular response to oxygen levelsGO:0071453550.302
regulation of histone modificationGO:0031056470.297
regulation of proteolysis involved in cellular protein catabolic processGO:1903050910.291
cellular response to oxygen containing compoundGO:19017012760.288
negative regulation of catabolic processGO:00098951040.282
response to cocaineGO:004222010.281
positive regulation of histone modificationGO:0031058290.273
coenzyme metabolic processGO:0006732650.254
response to purine containing compoundGO:0014074400.245
regulation of histone h3 k27 methylationGO:006108540.240
cell type specific apoptotic processGO:00972851250.238
regulation of cell cycle processGO:00105642660.231
Human
negative regulation of protein modification processGO:00314002000.231
regulation of chromatin modificationGO:1903308510.228
response to abiotic stimulusGO:00096283360.225
cellular response to dna damage stimulusGO:00069743790.221
protein dna complex subunit organizationGO:0071824800.220
protein localization to chromosomeGO:0034502300.204
response to lipidGO:00339932060.201
nervous system developmentGO:00073992930.200
regulation of histone methylationGO:0031060160.187
neurogenesisGO:00220081690.176
regulation of histone h3 k9 methylationGO:005157060.172
regulation of histone h3 k4 methylationGO:0051569100.170
response to acid chemicalGO:0001101660.168
modification dependent macromolecule catabolic processGO:00436322120.162
cellular response to organic cyclic compoundGO:00714071270.158
cellular response to hypoxiaGO:0071456510.157
response to ionizing radiationGO:0010212650.155
response to inorganic substanceGO:00100351270.155
regulation of cell cycle phase transitionGO:19019871260.155
chromosome segregationGO:00070591140.150
positive regulation of growthGO:0045927580.149
dna replication dependent nucleosome assemblyGO:0006335320.148
protein dna complex assemblyGO:0065004640.146
response to steroid hormoneGO:0048545800.139
regulation of mitotic cell cycleGO:00073461890.138
response to ammonium ionGO:006035970.131
cellular protein catabolic processGO:00442572610.119
negative regulation of mitotic cell cycle phase transitionGO:1901991850.118
response to nutrientGO:0007584200.117
positive regulation of hydrolase activityGO:00513453310.117
mitotic cell cycle phase transitionGO:00447721620.116
cell cycle phase transitionGO:00447701730.114
negative regulation of retinoic acid receptor signaling pathwayGO:004838740.111
protein processingGO:00164852260.110
cellular component morphogenesisGO:00329893140.109
response to increased oxygen levelsGO:003629640.108
mitotic sister chromatid segregationGO:0000070530.105
neuron differentiationGO:00301821380.104
nucleotide catabolic processGO:00091664080.103
negative regulation of cell cycleGO:00457861930.103
Human
chromosome separationGO:0051304230.100
dna replication independent nucleosome assemblyGO:0006336270.099
cellular response to lipidGO:00713961270.097
protein complex localizationGO:0031503310.094
response to nutrient levelsGO:0031667810.094
response to hormoneGO:00097251750.093
response to nerve growth factorGO:199008960.093
regulation of cell divisionGO:00513021160.092
response to extracellular stimulusGO:0009991850.090
dna replication independent nucleosome organizationGO:0034724270.089
response to vitaminGO:0033273130.089
generation of neuronsGO:00486991520.088
cellular response to growth factor stimulusGO:00713631970.088
lymphocyte activationGO:00466491330.087
regulation of gene silencingGO:0060968240.086
regulation of mitotic metaphase anaphase transitionGO:0030071260.086
positive regulation of cell developmentGO:0010720920.085
positive regulation of cell differentiationGO:00455972110.085
protein catabolic processGO:00301633250.084
single organism reproductive processGO:0044702980.084
response to organic cyclic compoundGO:00140702040.084
regulation of cell cycleGO:00517263930.083
Human
regulation of protein maturationGO:19033171500.081
purine nucleoside triphosphate metabolic processGO:00091444120.080
regulation of cell morphogenesisGO:00226041530.079
chromatin silencing at rdnaGO:000018350.079
multicellular organismal agingGO:001025930.078
embryo developmentGO:00097901230.076
nuclear divisionGO:00002801280.075
mitotic sister chromatid separationGO:0051306180.075
regulation of cell growthGO:00015581350.074
negative regulation of protein maturationGO:19033181420.071
regulation of cell differentiationGO:00455953930.070
mitotic nuclear divisionGO:00070671190.069
cellular response to dexamethasone stimulusGO:007154910.068
response to external biotic stimulusGO:00432072610.067
ribonucleoside catabolic processGO:00424544060.067
negative regulation of mitotic metaphase anaphase transitionGO:0045841170.066
regulation of nuclear divisionGO:0051783650.065
negative regulation of intrinsic apoptotic signaling pathwayGO:2001243400.065
negative regulation of epidermal cell differentiationGO:004560540.065
mitotic cell cycle checkpointGO:0007093680.065
growthGO:00400072020.063
regulation of anatomical structure morphogenesisGO:00226032860.063
ras protein signal transductionGO:0007265730.062
regulation of mitosisGO:0007088630.062
post embryonic developmentGO:000979120.060
metaphase anaphase transition of cell cycleGO:0044784210.059
sister chromatid segregationGO:0000819540.058
regulation of mitotic cell cycle phase transitionGO:19019901180.058
anatomical structure formation involved in morphogenesisGO:00486462840.057
purine ribonucleoside triphosphate catabolic processGO:00092073910.056
negative regulation of cell deathGO:00605483450.056
regulation of protein catabolic processGO:00421761550.055
response to ethanolGO:0045471110.055
cofactor metabolic processGO:0051186870.055
regulation of cellular amine metabolic processGO:0033238110.054
nucleoside triphosphate metabolic processGO:00091414220.054
vesicle mediated transportGO:00161923710.054
response to metal ionGO:0010038840.053
purine nucleoside triphosphate catabolic processGO:00091463920.053
reproductionGO:0000003630.052
regulation of purine nucleotide metabolic processGO:19005422640.052
response to biotic stimulusGO:00096072760.051
cellular response to hyperoxiaGO:007145540.051
carbohydrate derivative biosynthetic processGO:19011372070.051
protein maturationGO:00516042330.049
response to alcoholGO:0097305640.049
negative regulation of metaphase anaphase transition of cell cycleGO:1902100170.049
ribonucleoside triphosphate catabolic processGO:00092033910.048
negative regulation of cellular catabolic processGO:0031330830.048
endomembrane system organizationGO:00102561960.048
negative regulation of cell cycle processGO:00109481210.047
regulation of nervous system developmentGO:0051960880.047
modification dependent protein catabolic processGO:00199412090.047
regulation of small gtpase mediated signal transductionGO:00510561560.046
cellular response to alcoholGO:0097306290.045
negative regulation of protein processingGO:00109551420.045
response to bacteriumGO:00096171440.045
positive regulation of cell growthGO:0030307480.044
digestive system developmentGO:0055123750.044
regulation of growthGO:00400081650.044
protein ubiquitinationGO:00165673140.044
regulation of nucleotide catabolic processGO:00308112050.043
metencephalon developmentGO:002203720.043
cellular macromolecule catabolic processGO:00442653800.043
regulation of cell developmentGO:00602841610.043
regulation of chromosome segregationGO:0051983440.043
female gamete generationGO:000729220.042
negative regulation of programmed cell deathGO:00430693210.042
glycosyl compound catabolic processGO:19016584130.042
response to reactive oxygen speciesGO:0000302610.042
cellular response to decreased oxygen levelsGO:0036294510.042
dosage compensationGO:000754930.041
regulation of nucleoside metabolic processGO:00091182090.041
regulation of protein processingGO:00706131500.041
intracellular receptor signaling pathwayGO:00305221040.040
regulation of meiotic cell cycleGO:005144540.040
purine ribonucleotide catabolic processGO:00091544040.040
epithelial cell differentiationGO:00308551410.040
muscle cell differentiationGO:0042692630.040
negative regulation of cell divisionGO:0051782310.039
regulation of neuron differentiationGO:0045664700.039
ubiquitin dependent protein catabolic processGO:00065112060.038
cellular response to increased oxygen levelsGO:003629540.038
regulation of metaphase anaphase transition of cell cycleGO:1902099260.037
peptidyl lysine modificationGO:00182051440.037
positive regulation of cell deathGO:00109422630.036
nucleoside triphosphate catabolic processGO:00091433940.036
regulation of apoptotic signaling pathwayGO:20012331750.036
cell projection organizationGO:00300302520.036
regulation of proteolysisGO:00301622930.036
reproductive processGO:00224141060.035
regulation of purine nucleotide catabolic processGO:00331212050.035
metaphase anaphase transition of mitotic cell cycleGO:0007091210.035
circadian rhythmGO:0007623210.035
ribonucleoside triphosphate metabolic processGO:00091994120.035
microtubule cytoskeleton organizationGO:00002261760.034
developmental process involved in reproductionGO:0003006660.033
response to ketoneGO:1901654190.032
negative regulation of mitotic cell cycleGO:00459301020.032
cellular response to hydrogen peroxideGO:0070301370.032
actin filament based processGO:00300292240.032
positive regulation of nucleotide metabolic processGO:00459812300.032
response to lead ionGO:001028810.032
nucleotide biosynthetic processGO:00091651090.032
meiotic chromosome segregationGO:004513240.031
positive regulation of gtpase activityGO:00435471660.031
male meiosisGO:000714010.031
positive regulation of neurogenesisGO:0050769490.031
guanosine containing compound metabolic processGO:19010682440.031
regulation of intrinsic apoptotic signaling pathwayGO:2001242720.031
regulation of nucleotide metabolic processGO:00061402690.031
microtubule based processGO:00070172100.030
positive regulation of protein serine threonine kinase activityGO:00719021190.030
negative regulation of intracellular signal transductionGO:19025321830.029
small gtpase mediated signal transductionGO:0007264780.029
biological adhesionGO:00226103310.029
posttranscriptional regulation of gene expressionGO:00106082130.029
connective tissue developmentGO:0061448390.029
positive regulation of cellular amine metabolic processGO:003324070.029
positive regulation of cellular catabolic processGO:00313312840.029
negative regulation of epidermis developmentGO:004568350.028
organelle assemblyGO:00709251760.028
sensory organ morphogenesisGO:0090596210.028
regulation of cell cycle g1 s phase transitionGO:1902806420.028
positive regulation of neuron differentiationGO:0045666400.027
meiotic cell cycleGO:0051321130.027
oogenesisGO:004847720.027
cellular response to ethanolGO:007136110.027
skin developmentGO:0043588760.027
regulation of g1 s transition of mitotic cell cycleGO:2000045400.027
negative regulation of cellular protein catabolic processGO:1903363380.026
regulation of protein localizationGO:00328802960.026
regulation of mitotic sister chromatid separationGO:0010965270.025
amine metabolic processGO:0009308440.025
cell morphogenesisGO:00009022960.025
response to oxidative stressGO:00069791210.024
intrinsic apoptotic signaling pathwayGO:00971931270.024
positive regulation of nucleoside metabolic processGO:00459791860.024
i kappab kinase nf kappab signalingGO:00072491660.024
regulation of cytoskeleton organizationGO:00514931770.024
positive regulation of protein kinase activityGO:00458601900.024
chromatin remodelingGO:0006338550.024
cerebellar cortex developmentGO:002169510.024
positive regulation of immune system processGO:00026842830.024
organophosphate biosynthetic processGO:00904071630.024
purine nucleoside catabolic processGO:00061523980.024
cellular response to glucocorticoid stimulusGO:007138540.024
positive regulation of ras gtpase activityGO:00323201170.024
positive regulation of i kappab kinase nf kappab signalingGO:00431231320.023
single organism membrane organizationGO:00448022680.023
regulation of actin filament based processGO:00329701410.023
cation transportGO:00068123310.023
cellular amine metabolic processGO:0044106410.023
negative regulation of mitosisGO:0045839240.023
secretion by cellGO:00329402260.023
epidermal cell differentiationGO:0009913450.023
proteasome mediated ubiquitin dependent protein catabolic processGO:00431611560.023
establishment of protein localization to organelleGO:00725941720.023
epidermis developmentGO:0008544590.022
negative regulation of apoptotic processGO:00430663160.022
negative regulation of mitotic sister chromatid separationGO:2000816170.022
reproductive system developmentGO:0061458560.022
regulation of cell morphogenesis involved in differentiationGO:0010769830.022
regulation of mitotic sister chromatid segregationGO:0033047270.022
cell projection assemblyGO:00300311260.022
anaphase promoting complex dependent proteasomal ubiquitin dependent protein catabolic processGO:0031145250.022
positive regulation of developmental processGO:00510943140.021
male gamete generationGO:0048232220.021
apoptotic signaling pathwayGO:00971902680.021
positive regulation of protein phosphorylationGO:00019343130.021
protein localization to organelleGO:00333652800.021
locomotory behaviorGO:000762610.020
organonitrogen compound biosynthetic processGO:19015662000.020
cellular response to hormone stimulusGO:00328701250.020
meiosis iGO:000712740.020
cell part morphogenesisGO:00329901370.020
negative regulation of catalytic activityGO:00430863350.020
membrane organizationGO:00610242920.020
negative regulation of protein catabolic processGO:0042177590.020
response to growth factorGO:00708482050.020
head developmentGO:00603221080.020
response to dexamethasoneGO:007154810.020
cell growthGO:00160491600.019
multi organism reproductive processGO:0044703540.019
internal peptidyl lysine acetylationGO:0018393970.019
gtp catabolic processGO:00061842370.019
cell divisionGO:00513011680.019
purine ribonucleoside catabolic processGO:00461303980.019
response to hydrogen peroxideGO:0042542400.019
positive regulation of apoptotic processGO:00430652460.019
positive regulation of purine nucleotide metabolic processGO:19005442270.019
double strand break repairGO:00063021010.018
cellular response to corticosteroid stimulusGO:007138450.018
cytoplasmic transportGO:00164823790.018
protein polymerizationGO:0051258710.018
negative regulation of phosphate metabolic processGO:00459362670.018
determination of adult lifespanGO:000834020.018
positive regulation of cellular amino acid metabolic processGO:004576430.018
regulation of establishment of protein localizationGO:00702012420.018
proteasomal protein catabolic processGO:00104981760.018
response to other organismGO:00517072610.017
endocytosisGO:00068971590.017
regulation of kinase activityGO:00435493140.017
regulation of sister chromatid segregationGO:0033045270.017
negative regulation of cell cycle phase transitionGO:1901988890.017
negative regulation of hydrolase activityGO:00513461820.017
positive regulation of kinase activityGO:00336742040.017
negative regulation of muscle cell differentiationGO:0051148170.017
positive regulation of map kinase activityGO:0043406800.017
cellular protein complex assemblyGO:00436231880.017
positive regulation of transportGO:00510503360.017
chemical homeostasisGO:00488783060.017
dna biosynthetic processGO:0071897400.016
nucleotide excision repairGO:0006289310.016
mitotic spindle assembly checkpointGO:0007094140.016
peptidyl tyrosine modificationGO:00182121700.016
proteolysis involved in cellular protein catabolic processGO:00516032440.016
regulation of cellular ketone metabolic processGO:0010565500.016
dna catabolic processGO:0006308490.016
organelle fissionGO:00482851490.016
leukocyte proliferationGO:0070661740.016
hindbrain developmentGO:003090230.015
regulation of protein polymerizationGO:0032271630.015
regulation of actin cytoskeleton organizationGO:00329561160.015
nucleoside monophosphate metabolic processGO:00091231910.015
regulation of cellular amino acid metabolic processGO:000652160.015
regulation of map kinase activityGO:00434051080.015
cell cycle checkpointGO:00000751170.015
regulation of intracellular transportGO:00323861950.015
central nervous system developmentGO:00074171230.015
neuron developmentGO:00486661130.015
defense response to other organismGO:00985421290.015
purine ribonucleoside triphosphate metabolic processGO:00092054110.015
maintenance of location in cellGO:0051651620.015
blood circulationGO:00080151130.014
stem cell divisionGO:001714520.014
positive regulation of cytoskeleton organizationGO:0051495830.014
regulation of cellular component movementGO:00512703340.014
actin cytoskeleton organizationGO:00300362070.014
regulation of ion transmembrane transportGO:00347651320.014
positive regulation of transferase activityGO:00513472270.014
symbiosis encompassing mutualism through parasitismGO:00444031560.014
positive regulation of immune responseGO:00507781590.014
tissue regenerationGO:004224630.014
gland developmentGO:0048732480.014
regulation of ion transportGO:00432691890.014
cell adhesionGO:00071553250.014
regulation of secretion by cellGO:19035301770.013
eye developmentGO:0001654420.013
pharynx developmentGO:006046510.013
dna recombinationGO:0006310770.013
divalent metal ion transportGO:00708381520.013
peptidyl lysine dimethylationGO:001802730.013
dna replicationGO:00062601160.013
cell activationGO:00017752130.013
cerebellum developmentGO:002154920.013
purine nucleotide catabolic processGO:00061954050.013
regulation of immune responseGO:00507762010.013
multi organism cellular processGO:00447641560.013
regulation of anatomical structure sizeGO:00900661010.013
regulation of multi organism processGO:00439001570.012
protein acylationGO:00435431380.012
negative regulation of proteolysis involved in cellular protein catabolic processGO:1903051350.012
cartilage developmentGO:0051216310.012
guanosine containing compound catabolic processGO:19010692390.012
camera type eye developmentGO:0043010250.012
system processGO:00030083490.012
wnt signaling pathwayGO:00160551560.012
heterochromatin organizationGO:007082860.012
regulation of protein transportGO:00512232130.012
regulation of proteasomal protein catabolic processGO:0061136870.012
negative regulation of transferase activityGO:00513481240.012
regulation of protein modification by small protein conjugation or removalGO:19033201070.012
regulation of protein import into nucleusGO:0042306780.012
immune responseGO:00069553070.011
forebrain developmentGO:0030900260.011
positive regulation of cell proliferationGO:00082843010.011
regulation of protein complex assemblyGO:00432541470.011
digestive tract developmentGO:0048565750.011
telomere maintenanceGO:0000723320.011
muscle organ developmentGO:0007517560.011
hippocampus developmentGO:002176610.011
cell developmentGO:00484683280.011
divalent inorganic cation transportGO:00725111580.011
positive regulation of phosphorylationGO:00423273940.011
regulation of protein targetingGO:1903533910.011
atp catabolic processGO:00062001570.011
regulation of chromatin silencingGO:003193580.011
humoral immune responseGO:0006959490.011
negative regulation of apoptotic signaling pathwayGO:2001234970.011
response to glucocorticoidGO:0051384130.011
regulation of cell activationGO:00508651250.011
regulation of stem cell differentiationGO:2000736560.011
urogenital system developmentGO:0001655650.011
regulation of microtubule cytoskeleton organizationGO:0070507610.011
negative regulation of chromosome segregationGO:0051985180.011
multicellular organism reproductionGO:0032504420.011
response to fungusGO:000962040.011
purine nucleoside monophosphate metabolic processGO:00091261860.011
protein localization to nucleusGO:00345041360.011
regulation of dna templated transcription elongationGO:0032784230.010
negative regulation of transcription elongation from rna polymerase ii promoterGO:003424440.010
regulation of nucleocytoplasmic transportGO:0046822980.010
protein secretionGO:0009306980.010
spindle checkpointGO:0031577260.010
retina development in camera type eyeGO:0060041150.010
cell cycle g1 s phase transitionGO:0044843800.010
lipid localizationGO:00108761060.010
cell projection morphogenesisGO:00488581290.010
cellular response to reactive oxygen speciesGO:0034614500.010
negative regulation of cell differentiationGO:00455961710.010
positive regulation of nucleotide catabolic processGO:00308131850.010
response to lipopolysaccharideGO:0032496700.010

UHRF1 disease predictions

DiseaseDO term IDSizeProbabilityFunc Analog Org
nervous system diseaseDOID:8634310.115
neuropathyDOID:870520.115
peripheral neuropathyDOID:0060053120.084
disease of cellular proliferationDOID:145661740.043