Homo sapiens

0 known processes

CUL4A

cullin 4A

CUL4A biological process predictions


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Biological processGO term IDProcess sizeProbabilityFunc Analog Org
histone h2a monoubiquitinationGO:0035518110.999
Human
histone h2a ubiquitinationGO:0033522170.998
Human
chromatin modificationGO:00165682980.944
Human
regulation of cell cycle processGO:00105642660.937
Mouse
histone monoubiquitinationGO:0010390200.893
Human
protein monoubiquitinationGO:0006513390.884
Human
regulation of cell cycleGO:00517263930.859
Mouse
cellular response to dna damage stimulusGO:00069743790.856
Human Mouse
mitotic cell cycle processGO:19030472860.836
Mouse
protein modification by small protein conjugationGO:00324463420.806
Human
uv damage excision repairGO:007091470.777
Human
mitotic dna damage checkpointGO:0044773280.759
response to uvGO:0009411730.755
Human
response to light stimulusGO:0009416870.725
Human
modification dependent macromolecule catabolic processGO:00436322120.665
Mouse
chromatin organizationGO:00063253510.663
Human
cellular macromolecule catabolic processGO:00442653800.637
Mouse
negative regulation of mitotic cell cycle phase transitionGO:1901991850.601
protein catabolic processGO:00301633250.572
Mouse
g2 dna damage checkpointGO:0031572260.562
mitotic cell cycleGO:00002783260.551
Mouse
negative regulation of apoptotic processGO:00430663160.529
regulation of mitotic cell cycle phase transitionGO:19019901180.520
Mouse
cellular response to radiationGO:0071478650.507
Human
histone modificationGO:00165702510.505
Human
mitotic cell cycle checkpointGO:0007093680.500
cellular response to abiotic stimulusGO:00712141170.478
Human
mitotic dna integrity checkpointGO:0044774300.452
negative regulation of cell cycleGO:00457861930.434
cell cycle checkpointGO:00000751170.402
Mouse
negative regulation of cell cycle processGO:00109481210.400
proteasome mediated ubiquitin dependent protein catabolic processGO:00431611560.397
Mouse
cellular response to light stimulusGO:0071482340.394
Human
growthGO:00400072020.383
macromolecule methylationGO:0043414970.383
covalent chromatin modificationGO:00165692540.369
Human
cellular protein catabolic processGO:00442572610.307
Mouse
post embryonic developmentGO:000979120.303
response to abiotic stimulusGO:00096283360.299
Human
dna damage checkpointGO:0000077680.291
Mouse
regulation of mitosisGO:0007088630.258
response to radiationGO:00093141510.255
Human
positive regulation of protein transportGO:00512221350.253
negative regulation of cell deathGO:00605483450.249
mitotic cell cycle phase transitionGO:00447721620.238
Mouse
segmentationGO:003528240.237
multicellular organismal agingGO:001025930.235
regulation of growthGO:00400081650.232
histone lysine methylationGO:0034968500.231
cell cycle phase transitionGO:00447701730.228
Mouse
histone methylationGO:0016571600.227
positive regulation of protein catabolic processGO:0045732750.213
protein alkylationGO:0008213740.207
regulation of mitotic cell cycleGO:00073461890.203
Mouse
proteasomal protein catabolic processGO:00104981760.201
Mouse
proteolysis involved in cellular protein catabolic processGO:00516032440.199
Mouse
regulation of protein catabolic processGO:00421761550.198
cell competition in a multicellular organismGO:003521210.182
protein methylationGO:0006479740.181
ubiquitin dependent protein catabolic processGO:00065112060.164
Mouse
dna repairGO:00062811980.160
Human Mouse
wnt signaling pathwayGO:00160551560.154
negative regulation of transcription from rna polymerase ii promoterGO:00001222810.151
cellular response to uvGO:0034644320.145
Human
protein ubiquitination involved in ubiquitin dependent protein catabolic processGO:0042787370.143
histone h2a phosphorylationGO:199016430.142
female gamete generationGO:000729220.138
regulation of meiotic cell cycleGO:005144540.138
nucleocytoplasmic transportGO:00069131760.134
nuclear transportGO:00511691790.134
positive regulation of cellular amino acid metabolic processGO:004576430.131
methylationGO:00322591060.131
response to ionizing radiationGO:0010212650.125
regulation of chromosome segregationGO:0051983440.122
regulation of cell cycle phase transitionGO:19019871260.118
Mouse
negative regulation of mitotic cell cycleGO:00459301020.117
stem cell divisionGO:001714520.116
embryo developmentGO:00097901230.110
negative regulation of programmed cell deathGO:00430693210.110
regulation of chromosome organizationGO:00330441030.107
protein ubiquitinationGO:00165673140.106
Human
determination of adult lifespanGO:000834020.104
positive regulation of proteasomal protein catabolic processGO:1901800350.102
blastoderm segmentationGO:000735020.101
positive regulation of phosphorylationGO:00423273940.100
peptidyl lysine modificationGO:00182051440.098
modification dependent protein catabolic processGO:00199412090.096
Mouse
positive regulation of protein import into nucleusGO:0042307460.091
embryo development ending in birth or egg hatchingGO:0009792340.091
regulation of g1 s transition of mitotic cell cycleGO:2000045400.084
Mouse
histone threonine phosphorylationGO:003540570.083
regulation of cellular ketone metabolic processGO:0010565500.083
negative regulation of cell proliferationGO:00082852280.082
regulation of cellular amine metabolic processGO:0033238110.082
rna processingGO:00063962550.080
regulation of proteolysis involved in cellular protein catabolic processGO:1903050910.079
positive regulation of metaphase anaphase transition of cell cycleGO:190210160.076
positive regulation of organelle organizationGO:00106381950.076
ncrna processingGO:0034470830.074
peptidyl lysine methylationGO:0018022370.072
positive regulation of cellular component organizationGO:00511303760.072
regulation of transcription factor import into nucleusGO:0042990390.072
regulation of cell growthGO:00015581350.070
histone h3 k4 methylationGO:0051568270.065
adult locomotory behaviorGO:000834410.064
protein polyubiquitinationGO:00002091100.064
positive regulation of cell deathGO:00109422630.063
regulation of cytoplasmic transportGO:19036491490.062
immune system developmentGO:00025201950.060
Mouse
positive regulation of catabolic processGO:00098963100.059
regulation of protein stabilityGO:0031647870.058
dna integrity checkpointGO:0031570710.058
Mouse
mitotic nuclear divisionGO:00070671190.057
oocyte differentiationGO:000999420.057
neuron projection developmentGO:00311751060.056
regulation of mrna metabolic processGO:1903311530.056
vesicle mediated transportGO:00161923710.055
regulation of cellular protein catabolic processGO:1903362960.055
internal protein amino acid acetylationGO:00064751010.053
histone ubiquitinationGO:0016574310.052
Human
generation of neuronsGO:00486991520.052
positive regulation of apoptotic processGO:00430652460.051
reproductionGO:0000003630.051
oogenesisGO:004847720.051
mapk cascadeGO:00001652880.051
regulation of mitotic sister chromatid segregationGO:0033047270.050
microtubule based processGO:00070172100.050
cell growthGO:00160491600.048
positive regulation of mitotic cell cycle phase transitionGO:1901992190.048
Mouse
regulation of mitotic sister chromatid separationGO:0010965270.047
negative regulation of immune system processGO:00026831360.047
Mouse
ncrna metabolic processGO:00346601080.047
regulation of establishment of protein localizationGO:00702012420.047
signal transduction by phosphorylationGO:00230142970.046
regulation of rna splicingGO:0043484620.046
negative regulation of cell growthGO:0030308830.046
regulation of locomotionGO:00400123290.046
cell developmentGO:00484683280.045
Mouse
tripartite regional subdivisionGO:000735120.045
positive regulation of proteolysisGO:00458621420.044
anterior posterior axis specification embryoGO:000859520.044
positive regulation of protein phosphorylationGO:00019343130.044
regulation of nucleocytoplasmic transportGO:0046822980.043
single organism cellular localizationGO:19025803320.043
apoptotic signaling pathwayGO:00971902680.042
nuclear exportGO:0051168690.042
positive regulation of cytokine productionGO:00018191670.042
peptidyl threonine modificationGO:0018210450.041
positive regulation of transportGO:00510503360.041
single organism nuclear importGO:19025931040.041
cyclin catabolic processGO:000805460.041
regulation of proteasomal protein catabolic processGO:0061136870.040
mrna splicing via spliceosomeGO:0000398890.040
cellular response to endogenous stimulusGO:00714953360.040
tissue regenerationGO:004224630.040
organelle fissionGO:00482851490.039
nucleotide catabolic processGO:00091664080.039
receptor mediated endocytosisGO:0006898840.039
protein targeting to nucleusGO:00447441040.039
positive regulation of cell motilityGO:20001471770.038
endocytosisGO:00068971590.038
positive regulation of transcription factor import into nucleusGO:0042993250.038
mitotic g2 m transition checkpointGO:004481890.038
positive regulation of nucleocytoplasmic transportGO:0046824540.038
multicellular organism reproductionGO:0032504420.037
negative regulation of cell cycle phase transitionGO:1901988890.037
cellular ketone metabolic processGO:0042180800.037
myeloid cell differentiationGO:00300991170.037
Mouse
amine metabolic processGO:0009308440.036
regulation of intracellular transportGO:00323861950.036
rna splicingGO:00083801310.036
cellular macromolecular complex assemblyGO:00346223240.035
regulation of cellular component biogenesisGO:00440872810.035
regionalizationGO:0003002290.035
ribonucleoside triphosphate catabolic processGO:00092033910.034
regulation of cellular amino acid metabolic processGO:000652160.034
positive regulation of histone modificationGO:0031058290.034
cell morphogenesis involved in differentiationGO:00009041440.034
positive regulation of intracellular transportGO:00323881040.034
purine nucleotide catabolic processGO:00061954050.033
positive regulation of chromosome organizationGO:2001252410.033
nuclear importGO:00511701060.033
nervous system developmentGO:00073992930.033
cellular amino acid metabolic processGO:00065201160.033
multicellular organismal reproductive processGO:0048609400.033
cytoplasmic transportGO:00164823790.033
cell divisionGO:00513011680.033
regulation of protein targetingGO:1903533910.033
negative regulation of multicellular organismal processGO:00512413170.033
Mouse
regulation of rna stabilityGO:0043487230.032
regulation of cytokine productionGO:00018172320.032
regulation of nuclear divisionGO:0051783650.032
positive regulation of programmed cell deathGO:00430682490.031
protein importGO:00170381300.031
regulation of proteolysisGO:00301622930.031
positive regulation of cell proliferationGO:00082843010.031
Mouse
response to other organismGO:00517072610.030
ribonucleoprotein complex biogenesisGO:00226131160.030
negative regulation of growthGO:0045926970.030
anterior posterior axis specificationGO:000994820.030
negative regulation of proteolysisGO:00458611320.030
response to virusGO:00096151260.029
regulation of proteasomal ubiquitin dependent protein catabolic processGO:0032434710.029
mitotic g2 dna damage checkpointGO:000709570.028
cell projection organizationGO:00300302520.028
protein autoubiquitinationGO:0051865370.028
mrna processingGO:00063971330.028
positive regulation of immune responseGO:00507781590.028
purine ribonucleotide catabolic processGO:00091544040.028
positive regulation of cytoplasmic transportGO:1903651820.028
protein localization to nucleusGO:00345041360.027
regulation of protein localizationGO:00328802960.027
multi organism reproductive processGO:0044703540.027
mitotic sister chromatid segregationGO:0000070530.027
regulation of protein transportGO:00512232130.027
spermatid differentiationGO:004851540.026
cellular component morphogenesisGO:00329893140.026
taxisGO:00423301570.026
maturation of ssu rrnaGO:003049030.026
positive regulation of proteolysis involved in cellular protein catabolic processGO:1903052350.026
protein modification by small protein removalGO:0070646920.026
response to decreased oxygen levelsGO:0036293960.026
rho protein signal transductionGO:0007266260.025
regulation of cell divisionGO:00513021160.025
peripheral nervous system developmentGO:000742220.025
copii vesicle coatingGO:004820820.025
cytokine productionGO:00018162470.025
establishment of nucleus localizationGO:004002310.024
osteoblast differentiationGO:0001649920.024
regulation of immune responseGO:00507762010.024
regulation of mrna processingGO:0050684480.024
transcription factor import into nucleusGO:0042991400.024
g1 s transition of mitotic cell cycleGO:0000082780.023
Mouse
reproductive structure developmentGO:0048608550.023
regulation of protein processingGO:00706131500.023
purine containing compound catabolic processGO:00725234110.023
neuron remodelingGO:001632220.023
embryonic pattern specificationGO:000988050.023
engulfment of apoptotic cellGO:004365220.023
regulation of response to biotic stimulusGO:0002831550.023
digestionGO:0007586220.023
reproductive system developmentGO:0061458560.023
single organism reproductive processGO:0044702980.023
negative regulation of protein metabolic processGO:00512483910.022
multicellular organismal metabolic processGO:0044236340.022
protein acetylationGO:00064731160.022
oocyte developmentGO:004859910.022
positive regulation of proteasomal ubiquitin dependent protein catabolic processGO:0032436300.022
positive regulation of chromatin modificationGO:1903310300.022
nitrogen compound transportGO:00717051910.022
establishment of rna localizationGO:0051236390.022
digestive system developmentGO:0055123750.021
mrna metabolic processGO:00160711750.021
leukocyte proliferationGO:0070661740.021
positive regulation of intracellular protein transportGO:0090316760.021
cellular protein complex assemblyGO:00436231880.021
protein localization to organelleGO:00333652800.021
regulation of cell motilityGO:20001452990.021
positive regulation of hydrolase activityGO:00513453310.020
cellular response to nitrogen compoundGO:19016991440.020
metencephalon developmentGO:002203720.020
metal ion transportGO:00300012720.020
purine nucleoside triphosphate metabolic processGO:00091444120.020
cellular amine metabolic processGO:0044106410.020
reactive oxygen species metabolic processGO:0072593750.020
ossificationGO:00015031210.020
positive regulation of cellular protein catabolic processGO:1903364370.020
positive regulation of cell cycleGO:00457871400.020
Mouse
sex differentiationGO:0007548450.020
neuron developmentGO:00486661130.020
nucleoside triphosphate catabolic processGO:00091433940.019
regulation of meiosisGO:004002030.019
intrinsic apoptotic signaling pathwayGO:00971931270.019
immune responseGO:00069553070.019
cerebellum developmentGO:002154920.019
regulation of metaphase anaphase transition of cell cycleGO:1902099260.019
cullin deneddylationGO:001038890.019
positive regulation of immune system processGO:00026842830.019
regulation of protein maturationGO:19033171500.019
gonad developmentGO:0008406340.019
positive regulation of cell migrationGO:00303351720.019
negative regulation of peptidase activityGO:0010466910.019
response to organonitrogen compoundGO:00102431560.018
nucleoside phosphate catabolic processGO:19012924120.018
transcription elongation from rna polymerase ii promoterGO:0006368180.018
ribonucleoside triphosphate metabolic processGO:00091994120.018
rna export from nucleusGO:0006405330.018
hematopoietic or lymphoid organ developmentGO:00485341860.018
Mouse
locomotory behaviorGO:000762610.017
reproductive processGO:00224141060.017
establishment of protein localization to organelleGO:00725941720.017
regulation of tor signalingGO:0032006300.017
histone h3 k79 methylationGO:003472920.017
regulation of cellular component sizeGO:0032535820.017
protein maturationGO:00516042330.017
purine ribonucleoside metabolic processGO:00461284370.017
regulation of chromatin organizationGO:1902275560.017
jnk cascadeGO:0007254800.017
protein import into nucleusGO:00066061040.017
regulation of sister chromatid segregationGO:0033045270.017
regulation of mrna splicing via spliceosomeGO:0048024320.017
response to woundingGO:00096111680.017
regulation of dna metabolic processGO:00510521530.017
Mouse
negative regulation of endopeptidase activityGO:0010951840.016
regulation of protein localization to nucleusGO:1900180850.016
protein targetingGO:00066051870.016
response to organic cyclic compoundGO:00140702040.016
regulation of leukocyte activationGO:00026941150.016
regulation of histone h3 k4 methylationGO:0051569100.016
ribosome biogenesisGO:0042254480.016
peptidyl lysine trimethylationGO:0018023100.016
regulation of protein complex assemblyGO:00432541470.016
intracellular protein transportGO:00068862700.016
regulation of innate immune responseGO:0045088970.015
positive regulation of transferase activityGO:00513472270.015
tor signalingGO:0031929390.015
cellular response to organonitrogen compoundGO:00714171240.015
purine ribonucleoside triphosphate metabolic processGO:00092054110.015
positive regulation of cellular amine metabolic processGO:003324070.015
nucleobase containing compound transportGO:0015931510.015
cellular response to oxygen containing compoundGO:19017012760.015
regulation of intracellular protein transportGO:00331571230.015
ribonucleoprotein complex localizationGO:007116640.015
compound eye developmentGO:004874910.015
negative regulation of intracellular signal transductionGO:19025321830.015
cell activationGO:00017752130.015
rrna metabolic processGO:0016072400.015
cardiovascular system developmentGO:00723582620.015
rna splicing via transesterification reactions with bulged adenosine as nucleophileGO:0000377890.015
cell morphogenesisGO:00009022960.015
response to hormoneGO:00097251750.015
regulation of translationGO:0006417890.015
gamete generationGO:0007276250.015
development of primary sexual characteristicsGO:0045137350.015
regulation of protein import into nucleusGO:0042306780.014
positive regulation of meiotic cell cycleGO:005144620.014
metaphase anaphase transition of cell cycleGO:0044784210.014
negative regulation of locomotionGO:00400131180.014
behaviorGO:00076101120.014
maintenance of locationGO:00512351120.014
positive regulation of locomotionGO:00400171860.014
lipid biosynthetic processGO:00086101770.014
regulation of anatomical structure sizeGO:00900661010.014
regulation of gene expression epigeneticGO:0040029730.014
protein acylationGO:00435431380.014
mitotic sister chromatid separationGO:0051306180.014
regulation of mrna stabilityGO:0043488230.014
microtubule cytoskeleton organizationGO:00002261760.014
anterior posterior pattern specificationGO:000995290.014
circulatory system developmentGO:00723592620.014
cellular carbohydrate metabolic processGO:0044262840.014
response to external biotic stimulusGO:00432072610.014
small gtpase mediated signal transductionGO:0007264780.014
glial cell migrationGO:000834740.014
negative regulation of cellular protein catabolic processGO:1903363380.014
negative regulation of protein maturationGO:19033181420.013
purine ribonucleoside monophosphate catabolic processGO:00091691580.013
regulation of kinase activityGO:00435493140.013
memoryGO:000761330.013
gtp metabolic processGO:00460392390.013
developmental process involved in reproductionGO:0003006660.013
wound healingGO:00420601150.013
positive regulation of defense responseGO:0031349870.013
positive regulation of nfat protein import into nucleusGO:005153330.013
hemopoiesisGO:00300971800.013
Mouse
regulation of peptidase activityGO:00525471800.013
positive regulation of cell differentiationGO:00455972110.013
vasculature developmentGO:00019441810.013
regulation of antimicrobial humoral responseGO:000275910.013
leukocyte activationGO:00453211640.013
defense response to virusGO:0051607710.013
negative regulation of hydrolase activityGO:00513461820.013
regulation of cellular response to stressGO:00801352440.013
Mouse
negative regulation of cytokine productionGO:0001818820.012
somitogenesisGO:000175620.012
negative regulation of protein catabolic processGO:0042177590.012
defense responseGO:00069523150.012
nuclear divisionGO:00002801280.012
regulation of mitotic metaphase anaphase transitionGO:0030071260.012
purine nucleoside triphosphate catabolic processGO:00091463920.012
regulation of wnt signaling pathwayGO:00301111230.012
neuromuscular junction developmentGO:000752830.012
negative regulation of organelle organizationGO:00106391260.012
positive regulation of response to external stimulusGO:0032103880.012
cell fate commitment involved in pattern specificationGO:006058110.012
regulation of endopeptidase activityGO:00525481700.012
ribonucleoside catabolic processGO:00424544060.012
peptidyl tyrosine phosphorylationGO:00181081700.012
pattern specification processGO:0007389430.011
regulation of cytokine biosynthetic processGO:0042035350.011
rna splicing via transesterification reactionsGO:0000375900.011
rna localizationGO:0006403410.011
response to lipidGO:00339932060.011
regulation of cysteine type endopeptidase activityGO:20001161270.011
secretion by cellGO:00329402260.011
maturation of lsu rrnaGO:000047030.011
negative regulation of catalytic activityGO:00430863350.011
positive regulation of protein complex assemblyGO:0031334860.011
negative regulation of cell motilityGO:20001461040.011
peptidyl tyrosine modificationGO:00182121700.011
trophectodermal cell differentiationGO:000182930.011
response to oxygen levelsGO:00704821000.011
regulation of protein serine threonine kinase activityGO:00719001790.011
activation of protein kinase activityGO:0032147900.011
spermatid developmentGO:000728640.011
negative regulation of proteasomal protein catabolic processGO:1901799320.011
response to nitrogen compoundGO:19016981840.011
regulation of epithelial cell proliferationGO:00506781130.011
regulation of protein modification by small protein conjugation or removalGO:19033201070.011
positive regulation of ligase activityGO:0051351190.011
activation of immune responseGO:00022531140.011
cell cycle g1 s phase transitionGO:0044843800.011
Mouse
lipid metabolic processGO:00066293810.011
positive regulation of protein modification by small protein conjugation or removalGO:1903322610.011
innate immune responseGO:00450871780.011
protein stabilizationGO:0050821640.011
cell projection morphogenesisGO:00488581290.010
developmental growthGO:0048589480.010
stress activated mapk cascadeGO:0051403930.010
viral life cycleGO:00190581320.010
positive regulation of cellular component biogenesisGO:00440891580.010
regulation of response to external stimulusGO:00321012220.010
nucleic acid transportGO:0050657390.010
immune effector processGO:00022521590.010
secretionGO:00469032540.010
t cell proliferationGO:0042098450.010
negative regulation of phosphorus metabolic processGO:00105632670.010
intrinsic apoptotic signaling pathway in response to dna damageGO:0008630500.010
spindle elongationGO:005123140.010
negative regulation of multi organism processGO:0043901920.010
negative regulation of cellular protein metabolic processGO:00322693530.010
regulation of immune effector processGO:0002697910.010
cytokine biosynthetic processGO:0042089370.010
leukocyte migrationGO:00509001070.010
positive regulation of growthGO:0045927580.010
angiogenesisGO:00015251470.010

CUL4A disease predictions

DiseaseDO term IDSizeProbabilityFunc Analog Org
xeroderma pigmentosumDOID:005042780.075
nervous system diseaseDOID:8634310.015
sensory system diseaseDOID:00501552030.015
myopathyDOID:4231040.012
musculoskeletal system diseaseDOID:172230.012
muscle tissue diseaseDOID:661130.012
muscular diseaseDOID:00800001140.012