Homo sapiens

57 known processes

CUL4B

cullin 4B

(Aliases: SFM2,MRXHF2,DKFZp686F1470,MRXSC,KIAA0695,MRXS15)

CUL4B biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
post embryonic developmentGO:000979120.969
cellular macromolecule catabolic processGO:00442653800.464
nucleoside catabolic processGO:00091644080.381
purine ribonucleotide catabolic processGO:00091544040.374
cellular response to dna damage stimulusGO:00069743790.369
posttranscriptional regulation of gene expressionGO:00106082130.352
covalent chromatin modificationGO:00165692540.336
ribonucleoside catabolic processGO:00424544060.335
purine ribonucleoside catabolic processGO:00461303980.268
regulation of mitotic cell cycleGO:00073461890.246
Mouse Fly
negative regulation of protein metabolic processGO:00512483910.244
regulation of cell cycleGO:00517263930.242
Mouse Fly
purine nucleoside triphosphate catabolic processGO:00091463920.237
negative regulation of cellular protein metabolic processGO:00322693530.236
purine nucleoside triphosphate metabolic processGO:00091444120.235
histone h2a ubiquitinationGO:0033522170.231
nucleoside triphosphate catabolic processGO:00091433940.229
proteasomal protein catabolic processGO:00104981760.223
modification dependent macromolecule catabolic processGO:00436322120.221
regulation of purine nucleotide metabolic processGO:19005422640.206
cell developmentGO:00484683280.194
Rat Fly
glycosyl compound catabolic processGO:19016584130.193
purine nucleotide catabolic processGO:00061954050.184
cellular component morphogenesisGO:00329893140.175
Fly
histone modificationGO:00165702510.166
ribonucleoside triphosphate catabolic processGO:00092033910.164
protein modification by small protein removalGO:0070646920.163
neuromuscular junction developmentGO:000752830.163
ribonucleotide catabolic processGO:00092614050.162
chromatin modificationGO:00165682980.154
purine ribonucleoside metabolic processGO:00461284370.152
protein monoubiquitinationGO:0006513390.150
growthGO:00400072020.150
purine ribonucleoside triphosphate catabolic processGO:00092073910.148
ribonucleoside triphosphate metabolic processGO:00091994120.147
positive regulation of purine nucleotide catabolic processGO:00331231850.141
nucleoside triphosphate metabolic processGO:00091414220.132
positive regulation of nucleoside metabolic processGO:00459791860.132
positive regulation of nucleotide catabolic processGO:00308131850.131
regulation of nucleotide metabolic processGO:00061402690.131
organophosphate catabolic processGO:00464344300.127
embryo developmentGO:00097901230.122
ubiquitin dependent protein catabolic processGO:00065112060.120
nucleotide catabolic processGO:00091664080.116
nucleoside phosphate catabolic processGO:19012924120.116
regulation of cell differentiationGO:00455953930.114
rna processingGO:00063962550.110
rho protein signal transductionGO:0007266260.108
proteolysis involved in cellular protein catabolic processGO:00516032440.107
nucleus localizationGO:005164710.106
nervous system developmentGO:00073992930.105
Rat
reproductive processGO:00224141060.104
Fly
histone monoubiquitinationGO:0010390200.101
mitotic cell cycle processGO:19030472860.097
Mouse Fly
cellular macromolecular complex assemblyGO:00346223240.097
cell cell signalingGO:00072671550.094
positive regulation of purine nucleotide metabolic processGO:19005442270.090
purine nucleoside catabolic processGO:00061523980.089
cellular protein catabolic processGO:00442572610.088
multicellular organismal agingGO:001025930.088
proteasome mediated ubiquitin dependent protein catabolic processGO:00431611560.086
histone ubiquitinationGO:0016574310.086
small gtpase mediated signal transductionGO:0007264780.085
positive regulation of protein phosphorylationGO:00019343130.084
purine ribonucleoside triphosphate metabolic processGO:00092054110.078
spermatid developmentGO:000728640.076
organelle localizationGO:0051640840.073
positive regulation of cell proliferationGO:00082843010.073
behaviorGO:00076101120.072
positive regulation of meiotic cell cycleGO:005144620.070
positive regulation of phosphorylationGO:00423273940.070
regulation of nucleoside metabolic processGO:00091182090.069
single organism reproductive processGO:0044702980.068
Fly
mitotic cell cycleGO:00002783260.066
Mouse Fly
response to uvGO:0009411730.065
positive regulation of nucleotide metabolic processGO:00459812300.065
regulation of transferase activityGO:00513383550.064
positive regulation of cell cycleGO:00457871400.064
Mouse
guanosine containing compound metabolic processGO:19010682440.064
nucleoside monophosphate catabolic processGO:00091251590.063
regulation of cellular response to stressGO:00801352440.063
regulation of growthGO:00400081650.063
protein modification by small protein conjugationGO:00324463420.062
reproductive structure developmentGO:0048608550.060
cellular homeostasisGO:00197251960.059
cellular amino acid metabolic processGO:00065201160.057
regulation of cell cycle processGO:00105642660.057
Mouse Fly
positive regulation of chromosome organizationGO:2001252410.056
positive regulation of immune system processGO:00026842830.056
reproductive system developmentGO:0061458560.055
dna repairGO:00062811980.054
reproductionGO:0000003630.054
Fly
regulation of cell cycle phase transitionGO:19019871260.054
Mouse Fly
response to virusGO:00096151260.054
mitotic dna damage checkpointGO:0044773280.054
Fly
positive regulation of organelle organizationGO:00106381950.053
regulation of locomotionGO:00400123290.052
positive regulation of transferase activityGO:00513472270.052
rhythmic behaviorGO:000762220.051
spermatid differentiationGO:004851540.051
regulation of meiotic cell cycleGO:005144540.050
chromatin organizationGO:00063253510.050
embryonic epithelial tube formationGO:000183840.050
cell cycle checkpointGO:00000751170.050
Fly
determination of adult lifespanGO:000834020.049
tripartite regional subdivisionGO:000735120.049
positive regulation of hydrolase activityGO:00513453310.048
immune system developmentGO:00025201950.047
regulation of response to dna damage stimulusGO:2001020940.046
oogenesisGO:004847720.045
Fly
double strand break repairGO:00063021010.045
regulation of sequence specific dna binding transcription factor activityGO:00510902110.045
multicellular organismal reproductive processGO:0048609400.045
Fly
multicellular organism reproductionGO:0032504420.045
Fly
establishment of organelle localizationGO:0051656590.045
sex differentiationGO:0007548450.044
regulation of cellular amino acid metabolic processGO:000652160.044
ras protein signal transductionGO:0007265730.043
modification dependent protein catabolic processGO:00199412090.043
regulation of gtpase activityGO:00430871800.043
regulation of protein complex assemblyGO:00432541470.042
female gamete generationGO:000729220.042
Fly
hematopoietic or lymphoid organ developmentGO:00485341860.042
fertilizationGO:0009566120.042
regulation of cellular amine metabolic processGO:0033238110.041
purine nucleoside monophosphate catabolic processGO:00091281580.041
multi organism reproductive processGO:0044703540.041
Fly
regulation of cell motilityGO:20001452990.041
regulation of protein processingGO:00706131500.040
regulation of cellular component movementGO:00512703340.040
actin filament organizationGO:00070151280.039
negative regulation of catalytic activityGO:00430863350.038
purine ribonucleoside monophosphate catabolic processGO:00091691580.038
positive regulation of catabolic processGO:00098963100.038
Mouse Fly
ribonucleoside monophosphate metabolic processGO:00091611870.037
pattern specification processGO:0007389430.036
endocytosisGO:00068971590.036
blastoderm segmentationGO:000735020.036
chordate embryonic developmentGO:0043009340.036
membrane organizationGO:00610242920.035
cell projection organizationGO:00300302520.035
Rat
generation of neuronsGO:00486991520.035
Rat
regulation of nucleotide catabolic processGO:00308112050.035
cellular response to endogenous stimulusGO:00714953360.035
regulation of protein kinase activityGO:00458592890.034
histone h2a monoubiquitinationGO:0035518110.034
negative regulation of cell cycleGO:00457861930.034
Fly
protein maturationGO:00516042330.034
gtp metabolic processGO:00460392390.034
purine ribonucleoside monophosphate metabolic processGO:00091671860.034
positive regulation of cellular component organizationGO:00511303760.034
anterior posterior axis specificationGO:000994820.033
morphogenesis of embryonic epitheliumGO:001633140.033
locomotory behaviorGO:000762610.033
dna damage checkpointGO:0000077680.033
Fly
mrna metabolic processGO:00160711750.033
purine containing compound catabolic processGO:00725234110.033
negative regulation of protein modification processGO:00314002000.032
negative regulation of multicellular organismal processGO:00512413170.032
actin filament based processGO:00300292240.031
stem cell developmentGO:0048864690.031
regulation of mitotic cell cycle phase transitionGO:19019901180.031
Mouse Fly
regulation of atp catabolic processGO:1903289250.031
oocyte differentiationGO:000999420.031
cell cycle phase transitionGO:00447701730.031
Mouse Fly
positive regulation of cytokine productionGO:00018191670.030
negative regulation of phosphorus metabolic processGO:00105632670.030
organ morphogenesisGO:00098871470.030
response to abiotic stimulusGO:00096283360.029
regulation of gtp catabolic processGO:00331241800.029
segmentationGO:003528240.029
regulation of immune responseGO:00507762010.029
microtubule based processGO:00070172100.029
regulation of rho protein signal transductionGO:0035023790.029
negative regulation of cell differentiationGO:00455961710.029
atp catabolic processGO:00062001570.029
rna splicingGO:00083801310.028
circulatory system developmentGO:00723592620.028
chemotaxisGO:00069351570.028
cell morphogenesis involved in differentiationGO:00009041440.028
blastocyst developmentGO:000182430.028
peptidyl serine modificationGO:00182091060.028
mitotic cell cycle phase transitionGO:00447721620.028
Mouse Fly
skeletal system developmentGO:0001501790.028
g1 s transition of mitotic cell cycleGO:0000082780.028
Mouse
regulation of canonical wnt signaling pathwayGO:0060828880.027
actin cytoskeleton organizationGO:00300362070.027
lipid localizationGO:00108761060.027
mapk cascadeGO:00001652880.027
amine metabolic processGO:0009308440.027
protein ubiquitinationGO:00165673140.027
carbohydrate derivative biosynthetic processGO:19011372070.027
cell morphogenesisGO:00009022960.027
oocyte developmentGO:004859910.027
response to woundingGO:00096111680.027
atp metabolic processGO:00460341760.027
circadian sleep wake cycle sleepGO:005080220.026
stem cell maintenanceGO:0019827190.025
organelle fissionGO:00482851490.025
glycoprotein biosynthetic processGO:0009101910.025
response to other organismGO:00517072610.025
development of primary sexual characteristicsGO:0045137350.025
negative regulation of phosphate metabolic processGO:00459362670.025
vesicle mediated transportGO:00161923710.025
regulation of dna metabolic processGO:00510521530.025
neuron differentiationGO:00301821380.024
Rat
long term memoryGO:000761620.024
ribonucleoside monophosphate catabolic processGO:00091581580.024
developmental process involved in reproductionGO:0003006660.024
Fly
memoryGO:000761330.024
regulation of ras protein signal transductionGO:00465781550.023
negative regulation of mitotic cell cycleGO:00459301020.023
Fly
regulation of cell activationGO:00508651250.023
male gamete generationGO:0048232220.023
myeloid cell differentiationGO:00300991170.023
signal transduction by phosphorylationGO:00230142970.023
cell fate commitment involved in pattern specificationGO:006058110.022
cell activationGO:00017752130.022
cardiovascular system developmentGO:00723582620.022
regulation of protein ubiquitinationGO:0031396950.022
canonical wnt signaling pathwayGO:00600701160.022
mrna processingGO:00063971330.022
regulation of cytoplasmic transportGO:19036491490.021
Fly
negative regulation of cell proliferationGO:00082852280.021
golgi vesicle transportGO:0048193800.021
negative regulation of immune system processGO:00026831360.021
cyclin catabolic processGO:000805460.021
system processGO:00030083490.020
negative regulation of apoptotic processGO:00430663160.020
central nervous system developmentGO:00074171230.020
positive regulation of developmental processGO:00510943140.020
regulation of cellular component biogenesisGO:00440872810.020
regulation of ras gtpase activityGO:00323181280.020
gtp catabolic processGO:00061842370.020
gonad developmentGO:0008406340.020
regulation of g1 s transition of mitotic cell cycleGO:2000045400.020
Mouse
posttranscriptional gene silencingGO:0016441250.020
cellular amine metabolic processGO:0044106410.019
positive regulation of transportGO:00510503360.019
Fly
positive regulation of cellular catabolic processGO:00313312840.019
tube developmentGO:00352951250.019
mitotic nuclear divisionGO:00070671190.019
anatomical structure formation involved in morphogenesisGO:00486462840.019
Fly
regulation of response to woundingGO:19030341010.019
regulation of chromosome organizationGO:00330441030.019
single organism membrane organizationGO:00448022680.019
establishment of nucleus localizationGO:004002310.019
head developmentGO:00603221080.018
regulation of epithelial cell proliferationGO:00506781130.018
cell cycle g1 s phase transitionGO:0044843800.018
Mouse
positive regulation of cellular amine metabolic processGO:003324070.018
regulation of cytokine productionGO:00018172320.018
wnt signaling pathwayGO:00160551560.017
positive regulation of apoptotic processGO:00430652460.017
regulation of myeloid cell differentiationGO:0045637810.017
response to nitrogen compoundGO:19016981840.017
regulation of actin filament based processGO:00329701410.017
protein catabolic processGO:00301633250.017
Mouse Fly
regulation of rna splicingGO:0043484620.017
regulation of stress activated mapk cascadeGO:0032872840.016
cell part morphogenesisGO:00329901370.016
regulation of proteasomal ubiquitin dependent protein catabolic processGO:0032434710.016
protein stabilizationGO:0050821640.016
regulation of small gtpase mediated signal transductionGO:00510561560.016
positive regulation of immune responseGO:00507781590.016
leukocyte differentiationGO:0002521980.016
positive regulation of proteolysisGO:00458621420.016
myeloid leukocyte differentiationGO:0002573600.016
cytokine productionGO:00018162470.016
regulation of peptidyl serine phosphorylationGO:0033135500.016
skeletal system morphogenesisGO:0048705240.016
biological adhesionGO:00226103310.016
regulation of intracellular protein transportGO:00331571230.016
Fly
multicellular organismal metabolic processGO:0044236340.016
cellular cation homeostasisGO:00300031630.016
mitotic cell cycle checkpointGO:0007093680.015
Fly
regulation of cell migrationGO:00303342890.015
regulation of response to external stimulusGO:00321012220.015
vasculature developmentGO:00019441810.015
cell divisionGO:00513011680.015
positive regulation of programmed cell deathGO:00430682490.015
leukocyte activationGO:00453211640.015
stem cell divisionGO:001714520.015
nuclear divisionGO:00002801280.015
taxisGO:00423301570.015
regulation of protein polymerizationGO:0032271630.015
chemical homeostasisGO:00488783060.015
epithelial cell migrationGO:00106311190.015
regulation of protein stabilityGO:0031647870.015
neuron developmentGO:00486661130.015
Rat
regulation of leukocyte migrationGO:0002685630.015
positive regulation of cell differentiationGO:00455972110.015
defense responseGO:00069523150.015
regulation of purine nucleotide catabolic processGO:00331212050.015
negative regulation of protein maturationGO:19033181420.015
developmental growthGO:0048589480.015
cell adhesionGO:00071553250.014
anterior posterior axis specification embryoGO:000859520.014
negative regulation of protein processingGO:00109551420.014
axis elongationGO:000340140.014
cellular protein complex assemblyGO:00436231880.014
cytosolic calcium ion homeostasisGO:0051480890.014
regulation of mitosisGO:0007088630.014
dna conformation changeGO:00711031130.014
regulation of protein catabolic processGO:00421761550.014
Mouse Fly
positive regulation of cellular amino acid metabolic processGO:004576430.014
positive regulation of ras gtpase activityGO:00323201170.014
nucleoside monophosphate metabolic processGO:00091231910.014
muscle structure developmentGO:0061061980.014
intrinsic apoptotic signaling pathwayGO:00971931270.014
leukocyte proliferationGO:0070661740.014
regulation of actin filament polymerizationGO:0030833500.014
regulation of kinase activityGO:00435493140.014
glial cell migrationGO:000834740.014
cell growthGO:00160491600.014
positive regulation of histone modificationGO:0031058290.013
cell fate determinationGO:000170930.013
regulation of proteolysisGO:00301622930.013
cellular response to abiotic stimulusGO:00712141170.013
negative regulation of developmental processGO:00510932470.013
positive regulation of atpase activityGO:0032781190.013
negative regulation of protein phosphorylationGO:00019331400.013
regulation of anatomical structure sizeGO:00900661010.013
negative regulation of catabolic processGO:00098951040.013
calcium ion homeostasisGO:00550741220.013
negative regulation of cell deathGO:00605483450.013
receptor mediated endocytosisGO:0006898840.013
response to light stimulusGO:0009416870.013
hemopoiesisGO:00300971800.013
regulation of protein maturationGO:19033171500.013
neuroblast proliferationGO:000740540.013
purine nucleoside monophosphate metabolic processGO:00091261860.013
organophosphate biosynthetic processGO:00904071630.013
positive regulation of intracellular transportGO:00323881040.013
Fly
positive regulation of protein kinase activityGO:00458601900.012
guanosine containing compound catabolic processGO:19010692390.012
maintenance of locationGO:00512351120.012
regulation of vesicle mediated transportGO:00606271300.012
blood vessel developmentGO:00015681720.012
cellular divalent inorganic cation homeostasisGO:00725031280.012
neurogenesisGO:00220081690.012
Rat
mitotic sister chromatid separationGO:0051306180.012
neural nucleus developmentGO:0048857470.012
regulation of granulocyte differentiationGO:0030852110.012
gamete generationGO:0007276250.012
Fly
regulation of intracellular transportGO:00323861950.012
Fly
negative regulation of growthGO:0045926970.012
nuclear migrationGO:000709710.012
organelle fusionGO:0048284360.012
cullin deneddylationGO:001038890.012
positive regulation of cell deathGO:00109422630.012
rna interferenceGO:001624640.012
negative regulation of myeloid cell differentiationGO:0045638420.011
regulation of wnt signaling pathwayGO:00301111230.011
negative regulation of cellular component organizationGO:00511292350.011
peptidyl serine phosphorylationGO:00181051010.011
somatic stem cell maintenanceGO:003501940.011
regulation of translationGO:0006417890.011
sexual reproductionGO:0019953370.011
Fly
epithelial cell proliferationGO:00506731280.011
development of primary male sexual characteristicsGO:0046546230.011
protein deneddylationGO:0000338100.011
nuclear transcribed mrna catabolic processGO:0000956480.011
response to external biotic stimulusGO:00432072610.011
negative regulation of phosphorylationGO:00423261740.011
positive regulation of leukocyte activationGO:0002696800.011
regulation of atpase activityGO:0043462250.011
regulation of cell growthGO:00015581350.011
regulation of dephosphorylationGO:0035303960.011
regulation of cellular ketone metabolic processGO:0010565500.011
embryo development ending in birth or egg hatchingGO:0009792340.011
circadian behaviorGO:004851220.011
axon developmentGO:0061564340.011
regulation of nervous system developmentGO:0051960880.011
positive regulation of cell cycle phase transitionGO:1901989220.011
Mouse
negative regulation of hydrolase activityGO:00513461820.011
posttranscriptional gene silencing by rnaGO:0035194250.011
mitotic g2 m transition checkpointGO:004481890.011
Fly
regulation of anatomical structure morphogenesisGO:00226032860.011
cellular chemical homeostasisGO:00550821800.011
response to growth factorGO:00708482050.010
uv damage excision repairGO:007091470.010
positive regulation of gtpase activityGO:00435471660.010
negative regulation of transcription from rna polymerase ii promoterGO:00001222810.010
ncrna catabolic processGO:0034661140.010
cellular response to oxygen containing compoundGO:19017012760.010
primary neural tube formationGO:001402030.010
positive regulation of mononuclear cell proliferationGO:0032946470.010
regulation of cytoskeleton organizationGO:00514931770.010

CUL4B disease predictions

DiseaseDO term IDSizeProbabilityFunc Analog Org
nervous system diseaseDOID:8634310.018
neurodegenerative diseaseDOID:12891020.018
central nervous system diseaseDOID:3311860.018
sensory system diseaseDOID:00501552030.013
hematopoietic system diseaseDOID:741000.012
anemiaDOID:2355550.012
immune system diseaseDOID:29141550.012