Homo sapiens

115 known processes

ZIC3

Zic family member 3 (odd-paired homolog, Drosophila)

(Aliases: HTX1,ZNF203,HTX)

ZIC3 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
regulation of cellular component movementGO:00512703340.275
regulation of cellular ketone metabolic processGO:0010565500.231
regulation of cell differentiationGO:00455953930.226
regulation of locomotionGO:00400123290.222
cardiac cell fate determinationGO:006091330.205
locomotory behaviorGO:000762610.185
regulation of cellular amino acid metabolic processGO:000652160.182
cell cell signalingGO:00072671550.174
negative regulation of transcription from rna polymerase ii promoterGO:00001222810.167
negative regulation of developmental processGO:00510932470.164
nervous system developmentGO:00073992930.164
Human Mouse
secretion by cellGO:00329402260.162
somatic stem cell maintenanceGO:003501940.155
regulation of cellular amine metabolic processGO:0033238110.147
cellular ketone metabolic processGO:0042180800.143
regulation of cell migrationGO:00303342890.143
negative regulation of cell differentiationGO:00455961710.141
circulatory system developmentGO:00723592620.139
enzyme linked receptor protein signaling pathwayGO:00071673030.138
Fly
hindbrain developmentGO:003090230.138
system processGO:00030083490.137
ion transmembrane transportGO:00342203380.135
cell developmentGO:00484683280.135
cellular amine metabolic processGO:0044106410.131
regulation of hormone levelsGO:00108171250.129
cell fate determinationGO:000170930.127
negative regulation of multicellular organismal processGO:00512413170.126
cellular amino acid metabolic processGO:00065201160.125
signal transduction by phosphorylationGO:00230142970.123
positive regulation of cell proliferationGO:00082843010.119
stem cell differentiationGO:0048863930.119
regulation of cell motilityGO:20001452990.119
amine metabolic processGO:0009308440.115
cell morphogenesisGO:00009022960.111
neuron fate commitmentGO:004866320.110
cellular response to endogenous stimulusGO:00714953360.108
regulation of cell cycleGO:00517263930.107
positive regulation of cellular amino acid metabolic processGO:004576430.104
chemical homeostasisGO:00488783060.102
positive regulation of cellular amine metabolic processGO:003324070.100
pituitary gland developmentGO:002198320.099
embryonic morphogenesisGO:0048598850.098
stem cell developmentGO:0048864690.097
positive regulation of developmental processGO:00510943140.097
regulation of protein localizationGO:00328802960.096
cellular component morphogenesisGO:00329893140.093
organ morphogenesisGO:00098871470.092
tube developmentGO:00352951250.091
cation transportGO:00068123310.090
anatomical structure formation involved in morphogenesisGO:00486462840.090
regulation of establishment of protein localizationGO:00702012420.090
cytoplasmic transportGO:00164823790.088
divalent inorganic cation homeostasisGO:00725071360.088
wnt signaling pathwayGO:00160551560.085
cranial nerve developmentGO:002154540.084
positive regulation of phosphorylationGO:00423273940.083
regulation of protein transportGO:00512232130.083
neuron differentiationGO:00301821380.082
regulation of secretionGO:00510461940.082
regulation of cell developmentGO:00602841610.082
cellular response to dna damage stimulusGO:00069743790.081
positive regulation of cell developmentGO:0010720920.080
brain developmentGO:0007420970.080
Human
cellular chemical homeostasisGO:00550821800.080
positive regulation of cell motilityGO:20001471770.079
positive regulation of cell differentiationGO:00455972110.078
cation transmembrane transportGO:00986552380.078
regulation of anatomical structure morphogenesisGO:00226032860.076
generation of neuronsGO:00486991520.076
nerve developmentGO:002167540.075
regulation of secretion by cellGO:19035301770.075
epithelium developmentGO:00604292270.075
cardiac muscle cell contractionGO:008600340.073
regulation of canonical wnt signaling pathwayGO:0060828880.073
canonical wnt signaling pathwayGO:00600701160.072
negative regulation of cellular protein metabolic processGO:00322693530.071
neurological system processGO:00508771630.071
negative regulation of phosphorus metabolic processGO:00105632670.071
negative regulation of protein metabolic processGO:00512483910.071
positive regulation of cellular component movementGO:00512721810.071
segmentationGO:003528240.070
post embryonic developmentGO:000979120.070
Fly
mapk cascadeGO:00001652880.069
secretionGO:00469032540.068
central nervous system developmentGO:00074171230.068
Human
negative regulation of cell proliferationGO:00082852280.067
transmembrane transportGO:00550853990.067
cardiovascular system developmentGO:00723582620.066
regulation of mapk cascadeGO:00434082620.066
positive regulation of hydrolase activityGO:00513453310.065
behaviorGO:00076101120.063
cellular homeostasisGO:00197251960.063
head developmentGO:00603221080.063
Human
regulation of wnt signaling pathwayGO:00301111230.062
negative regulation of apoptotic processGO:00430663160.062
epithelial cell differentiationGO:00308551410.062
endodermal cell fate specificationGO:000171440.061
g protein coupled receptor signaling pathwayGO:00071862070.061
embryonic camera type eye developmentGO:003107620.060
endodermal cell fate commitmentGO:000171140.059
positive regulation of cellular component organizationGO:00511303760.059
muscle system processGO:0003012810.058
negative regulation of gliogenesisGO:001401430.058
positive regulation of monocyte chemotactic protein 1 productionGO:007163930.057
chromatin organizationGO:00063253510.057
regulation of cell cycle processGO:00105642660.057
skeletal system developmentGO:0001501790.057
regulation of ion transportGO:00432691890.056
cardiac right ventricle morphogenesisGO:000321530.056
blood vessel developmentGO:00015681720.056
tissue morphogenesisGO:0048729960.055
chromatin modificationGO:00165682980.055
transmembrane receptor protein serine threonine kinase signaling pathwayGO:00071781250.055
Fly
female gamete generationGO:000729220.055
regulation of cytoplasmic transportGO:19036491490.054
mitotic cell cycleGO:00002783260.053
cellular response to growth factor stimulusGO:00713631970.053
cation homeostasisGO:00550801890.053
osteoblast differentiationGO:0001649920.053
negative regulation of protein modification processGO:00314002000.053
regulation of epithelial cell migrationGO:0010632930.052
oogenesisGO:004847720.052
neurogenesisGO:00220081690.052
morphogenesis of embryonic epitheliumGO:001633140.052
biological adhesionGO:00226103310.051
ameboidal type cell migrationGO:00016671350.050
positive regulation of programmed cell deathGO:00430682490.050
negative regulation of programmed cell deathGO:00430693210.050
cell adhesionGO:00071553250.050
adult locomotory behaviorGO:000834410.049
metencephalon developmentGO:002203720.049
regulation of kinase activityGO:00435493140.049
negative regulation of transportGO:00510511760.049
limbic system developmentGO:002176130.049
positive regulation of cell migrationGO:00303351720.049
vasculature developmentGO:00019441810.049
actin filament based processGO:00300292240.049
single organism cellular localizationGO:19025803320.049
cell projection organizationGO:00300302520.048
hormone secretionGO:0046879650.048
inorganic cation transmembrane transportGO:00986621940.048
negative regulation of cell deathGO:00605483450.048
response to growth factorGO:00708482050.048
regulation of membrane potentialGO:0042391950.047
response to oxygen containing compoundGO:19017003690.047
intracellular protein transportGO:00068862700.047
regulation of stem cell differentiationGO:2000736560.046
response to abiotic stimulusGO:00096283360.046
positive regulation of transportGO:00510503360.046
inorganic ion transmembrane transportGO:00986602310.046
positive regulation of locomotionGO:00400171860.046
cerebellum developmentGO:002154920.044
transmembrane receptor protein tyrosine kinase signaling pathwayGO:00071691810.044
tube morphogenesisGO:0035239950.044
positive regulation of transferase activityGO:00513472270.044
regulation of male gonad developmentGO:200001840.044
chemotaxisGO:00069351570.044
single organism cell adhesionGO:00986021790.044
cellular divalent inorganic cation homeostasisGO:00725031280.044
neuron developmentGO:00486661130.043
regulation of sequence specific dna binding transcription factor activityGO:00510902110.043
negative regulation of phosphate metabolic processGO:00459362670.043
metal ion homeostasisGO:00550651690.043
regulation of cellular response to stressGO:00801352440.043
regulation of cellular component biogenesisGO:00440872810.043
positive regulation of mapk cascadeGO:00434101900.043
sex determinationGO:000753030.042
calcium ion homeostasisGO:00550741220.041
ion homeostasisGO:00508012300.041
regulation of protein kinase activityGO:00458592890.041
regulation of peptidase activityGO:00525471800.041
digestive tract developmentGO:0048565750.041
regulation of nucleotide metabolic processGO:00061402690.041
positive regulation of protein phosphorylationGO:00019343130.040
growthGO:00400072020.040
cardiac muscle contractionGO:0060048340.040
nucleocytoplasmic transportGO:00069131760.040
regulation of endopeptidase activityGO:00525481700.039
peripheral nervous system developmentGO:000742220.039
negative regulation of locomotionGO:00400131180.039
ossificationGO:00015031210.039
membrane organizationGO:00610242920.039
cellular metal ion homeostasisGO:00068751460.039
regulation of epithelial cell proliferationGO:00506781130.039
positive regulation of secretion by cellGO:19035321080.039
ras protein signal transductionGO:0007265730.039
cytokine productionGO:00018162470.039
regulation of transferase activityGO:00513383550.038
regulation of intracellular transportGO:00323861950.038
hormone transportGO:0009914680.038
forebrain developmentGO:0030900260.038
regulation of ossificationGO:0030278580.038
negative regulation of cell cycleGO:00457861930.038
response to cytokineGO:00340972320.037
embryo developmentGO:00097901230.037
monovalent inorganic cation transportGO:00156721280.037
spinal cord developmentGO:002151040.037
metal ion transportGO:00300012720.037
nuclear transportGO:00511691790.037
regulation of cytokine productionGO:00018172320.036
taxisGO:00423301570.036
epithelial cell proliferationGO:00506731280.036
cellular macromolecule catabolic processGO:00442653800.036
positive regulation of catabolic processGO:00098963100.036
single organism membrane organizationGO:00448022680.036
blood vessel morphogenesisGO:00485141620.036
cell morphogenesis involved in differentiationGO:00009041440.035
organ formationGO:004864530.035
rho protein signal transductionGO:0007266260.035
regulation of intracellular protein transportGO:00331571230.035
positive regulation of sequence specific dna binding transcription factor activityGO:00510911310.035
regulation of dna metabolic processGO:00510521530.035
negative regulation of cell migrationGO:00303361020.035
nitrogen compound transportGO:00717051910.035
cell projection morphogenesisGO:00488581290.034
positive regulation of cell deathGO:00109422630.033
nucleoside catabolic processGO:00091644080.033
urogenital system developmentGO:0001655650.033
cellular response to oxygen containing compoundGO:19017012760.033
regulation of neurogenesisGO:0050767820.033
regulation of proteolysisGO:00301622930.033
cell divisionGO:00513011680.033
mesenchymal cell differentiationGO:0048762520.033
cellular lipid metabolic processGO:00442553030.033
protein ubiquitinationGO:00165673140.033
heart developmentGO:0007507950.033
protein catabolic processGO:00301633250.033
small gtpase mediated signal transductionGO:0007264780.032
negative regulation of cellular component organizationGO:00511292350.032
embryonic camera type eye morphogenesisGO:004859620.032
negative regulation of canonical wnt signaling pathwayGO:0090090550.032
mitotic cell cycle processGO:19030472860.032
epithelium migrationGO:00901321190.032
specification of organ identityGO:001009230.032
regulation of cell growthGO:00015581350.032
regulation of mitotic cell cycleGO:00073461890.032
lipid metabolic processGO:00066293810.032
embryonic camera type eye formationGO:006090020.032
regulation of cell adhesionGO:00301551660.031
embryonic eye morphogenesisGO:004804820.031
regulation of atrial cardiac muscle cell membrane repolarizationGO:006037240.031
cellular ion homeostasisGO:00068731680.031
ribonucleoside triphosphate metabolic processGO:00091994120.031
muscle contractionGO:0006936730.031
positive regulation of proteolysisGO:00458621420.031
pattern specification processGO:0007389430.031
cell activationGO:00017752130.031
regulation of transmembrane receptor protein serine threonine kinase signaling pathwayGO:0090092900.031
purine ribonucleoside metabolic processGO:00461284370.031
positive regulation of cell cycleGO:00457871400.031
cell growthGO:00160491600.031
signal releaseGO:0023061700.031
positive regulation of epithelial cell proliferationGO:0050679650.031
digestive system developmentGO:0055123750.031
purine nucleotide catabolic processGO:00061954050.031
organonitrogen compound biosynthetic processGO:19015662000.030
cellular calcium ion homeostasisGO:00068741170.030
endocrine system developmentGO:0035270260.030
cellular macromolecular complex assemblyGO:00346223240.030
positive regulation of secretionGO:00510471160.030
muscle structure developmentGO:0061061980.030
glycosyl compound catabolic processGO:19016584130.030
vesicle mediated transportGO:00161923710.030
regulation of protein serine threonine kinase activityGO:00719001790.030
striated muscle contractionGO:0006941520.030
regulation of system processGO:00440571010.030
nucleoside phosphate catabolic processGO:19012924120.030
cardiac ventricle formationGO:000321120.030
regulation of neuron differentiationGO:0045664700.030
negative regulation of intracellular signal transductionGO:19025321830.030
positive regulation of male gonad developmentGO:200002030.030
positive regulation of cytokine productionGO:00018191670.030
positive regulation of protein transportGO:00512221350.029
positive regulation of cellular catabolic processGO:00313312840.029
anterior posterior axis specificationGO:000994820.029
Zebrafish
negative regulation of catalytic activityGO:00430863350.029
posttranscriptional regulation of gene expressionGO:00106082130.029
regulation of response to external stimulusGO:00321012220.029
aortic valve developmentGO:000317630.029
anion transportGO:00068201610.029
purine nucleoside catabolic processGO:00061523980.029
regulation of osteoblast differentiationGO:0045667380.029
multicellular organismal agingGO:001025930.029
positive regulation of kinase activityGO:00336742040.029
histone modificationGO:00165702510.029
mesenchyme developmentGO:0060485590.029
positive regulation of protein kinase activityGO:00458601900.028
somitogenesisGO:000175620.028
cellular cation homeostasisGO:00300031630.028
regulation of purine nucleotide metabolic processGO:19005422640.028
regulation of nervous system developmentGO:0051960880.028
ribonucleoside catabolic processGO:00424544060.028
negative regulation of cell motilityGO:20001461040.028
optic nerve developmentGO:002155420.028
organophosphate catabolic processGO:00464344300.028
purine ribonucleotide catabolic processGO:00091544040.028
single organismal cell cell adhesionGO:00163371480.028
mitotic cell cycle phase transitionGO:00447721620.028
cell cycle phase transitionGO:00447701730.028
neuroblast proliferationGO:000740540.028
epithelial cell migrationGO:00106311190.028
sensory organ developmentGO:0007423520.028
blastoderm segmentationGO:000735020.027
negative regulation of wnt signaling pathwayGO:0030178690.027
neural crest cell developmentGO:001403230.027
positive regulation of nervous system developmentGO:0051962540.027
detection of stimulusGO:0051606850.027
forebrain generation of neuronsGO:002187230.027
covalent chromatin modificationGO:00165692540.027
neuron projection developmentGO:00311751060.027
positive regulation of apoptotic processGO:00430652460.027
neuromuscular junction developmentGO:000752830.027
cellular response to cytokine stimulusGO:00713451810.026
determination of adult lifespanGO:000834020.026
purine ribonucleoside triphosphate catabolic processGO:00092073910.026
nucleotide catabolic processGO:00091664080.026
regulation of nucleocytoplasmic transportGO:0046822980.026
nucleoside triphosphate metabolic processGO:00091414220.026
forebrain regionalizationGO:002187130.026
formation of primary germ layerGO:0001704420.026
protein modification by small protein conjugationGO:00324463420.026
response to lipidGO:00339932060.026
purine nucleoside triphosphate catabolic processGO:00091463920.026
defense responseGO:00069523150.026
regulation of growthGO:00400081650.026
synaptic transmissionGO:0007268610.026
digestive tract morphogenesisGO:0048546560.026
pancreatic a cell differentiationGO:000331010.026
reproductive processGO:00224141060.026
Fly
protein localization to organelleGO:00333652800.025
negative regulation of phosphorylationGO:00423261740.025
cardiac chamber formationGO:000320720.025
regulation of transmembrane transportGO:00347621390.025
regulation of cell divisionGO:00513021160.025
regulation of cell morphogenesisGO:00226041530.025
heart formationGO:006091420.025
regulation of synaptic plasticityGO:004816730.025
purine nucleoside triphosphate metabolic processGO:00091444120.024
ribonucleotide catabolic processGO:00092614050.024
regulation of cysteine type endopeptidase activityGO:20001161270.024
protein acylationGO:00435431380.024
second messenger mediated signalingGO:0019932780.024
muscle tissue developmentGO:0060537620.024
regulation of ion transmembrane transportGO:00347651320.024
positive regulation of neurogenesisGO:0050769490.024
mesenchymal cell developmentGO:0014031500.024
divalent inorganic cation transportGO:00725111580.024
positive regulation of peptidase activityGO:0010952880.024
inner ear morphogenesisGO:004247240.024
negative regulation of cellular component movementGO:00512711060.024
bmp signaling pathway involved in heart developmentGO:006131230.024
response to decreased oxygen levelsGO:0036293960.024
regulation of actin filament based processGO:00329701410.024
epithelial tube branching involved in lung morphogenesisGO:006044140.024
regulation of hormone secretionGO:0046883570.023
hematopoietic or lymphoid organ developmentGO:00485341860.023
ribonucleoside triphosphate catabolic processGO:00092033910.023
blastocyst formationGO:000182530.023
single organism reproductive processGO:0044702980.023
Fly
divalent metal ion transportGO:00708381520.023
regulation of neural precursor cell proliferationGO:200017740.023
gtp catabolic processGO:00061842370.023
positive regulation of cysteine type endopeptidase activity involved in apoptotic processGO:0043280690.023
response to woundingGO:00096111680.023
actin mediated cell contractionGO:0070252120.023
regulation of cell activationGO:00508651250.023
protein targetingGO:00066051870.023
negative regulation of cellular amine metabolic processGO:003323930.022
carbohydrate metabolic processGO:00059752070.022
purine ribonucleoside triphosphate metabolic processGO:00092054110.022
purine ribonucleoside catabolic processGO:00461303980.022
actin filament based movementGO:0030048170.022
establishment of protein localization to organelleGO:00725941720.022
oocyte differentiationGO:000999420.022
endoderm formationGO:0001706330.022
glial cell migrationGO:000834740.022
cellular response to lipidGO:00713961270.022
immune system developmentGO:00025201950.022
chordate embryonic developmentGO:0043009340.022
immune responseGO:00069553070.022
positive regulation of cysteine type endopeptidase activityGO:2001056790.022
oxidation reduction processGO:00551143960.022
endochondral bone morphogenesisGO:006035030.022
cellular potassium ion transportGO:0071804600.022
regulation of glial cell proliferationGO:006025140.022
positive regulation of aldosterone biosynthetic processGO:003234920.022
cartilage condensationGO:000150210.021
endothelial cell migrationGO:0043542860.021
regulation of purine nucleotide catabolic processGO:00331212050.021
positive regulation of immune system processGO:00026842830.021
striated muscle tissue developmentGO:0014706590.021
apoptotic signaling pathwayGO:00971902680.021
cytosolic calcium ion homeostasisGO:0051480890.021
carbohydrate derivative biosynthetic processGO:19011372070.021
anterior posterior axis specification embryoGO:000859520.021
positive regulation of cell cycle processGO:00900681060.021
action potentialGO:0001508340.021
epithelial tube morphogenesisGO:0060562380.021
regulation of cysteine type endopeptidase activity involved in apoptotic processGO:00432811160.021
negative regulation of cell growthGO:0030308830.021
positive regulation of nucleoside metabolic processGO:00459791860.021
angiogenesisGO:00015251470.021
positive regulation of neural precursor cell proliferationGO:200017920.021
negative regulation of cellular amino acid metabolic processGO:004576320.021
astrocyte differentiationGO:004870840.021
regulation of cell cycle phase transitionGO:19019871260.021
regulation of metal ion transportGO:00109591200.021
renal system developmentGO:0072001630.021
blastocyst developmentGO:000182430.021
dephosphorylationGO:00163112090.021
potassium ion transmembrane transportGO:0071805600.021
translationGO:00064121320.021
calcium ion transportGO:00068161470.021
negative regulation of immune system processGO:00026831360.021
prostate gland developmentGO:003085030.021
morphogenesis of an epitheliumGO:0002009600.021
response to other organismGO:00517072610.021
skeletal system morphogenesisGO:0048705240.021
protein acetylationGO:00064731160.021
negative regulation of protein phosphorylationGO:00019331400.021
nucleoside triphosphate catabolic processGO:00091433940.021
guanosine containing compound catabolic processGO:19010692390.020
rhythmic behaviorGO:000762220.020
regulation of nucleotide catabolic processGO:00308112050.020
connective tissue developmentGO:0061448390.020
oocyte developmentGO:004859910.020
regenerationGO:003109940.020
response to organic cyclic compoundGO:00140702040.020
endomembrane system organizationGO:00102561960.020
photoreceptor cell differentiationGO:004653020.020
cell fate commitmentGO:0045165270.020
response to oxygen levelsGO:00704821000.020
circadian behaviorGO:004851220.020
amide transportGO:0042886760.020
negative regulation of glial cell proliferationGO:006025320.020
cell part morphogenesisGO:00329901370.020
protein localization to membraneGO:00726571600.020
leukocyte activationGO:00453211640.020
purine containing compound catabolic processGO:00725234110.020
negative regulation of growthGO:0045926970.020
positive regulation of purine nucleotide metabolic processGO:19005442270.019
regulation of protein secretionGO:0050708860.019
cellular protein catabolic processGO:00442572610.019
regulation of response to dna damage stimulusGO:2001020940.019
intracellular receptor signaling pathwayGO:00305221040.019
signal transduction by p53 class mediatorGO:0072331720.019
forebrain neuron differentiationGO:002187930.019
regulation of nucleoside metabolic processGO:00091182090.019
tripartite regional subdivisionGO:000735120.019
regulation of protein complex assemblyGO:00432541470.019
hemopoiesisGO:00300971800.019
brain morphogenesisGO:004885410.019
startle responseGO:000196430.019
neurotransmitter secretionGO:000726940.019
positive regulation of cellular component biogenesisGO:00440891580.019
negative regulation of mitotic cell cycleGO:00459301020.019
positive regulation of stem cell differentiationGO:2000738290.019
heart morphogenesisGO:0003007480.019
trophectodermal cell differentiationGO:000182930.019
bone mineralizationGO:0030282340.018
response to transforming growth factor betaGO:0071559940.018
regulation of muscle system processGO:0090257530.018
regulation of multi organism processGO:00439001570.018
regulation of cell morphogenesis involved in differentiationGO:0010769830.018
positive regulation of hormone biosynthetic processGO:004688640.018
dna repairGO:00062811980.018
mesenchymal to epithelial transition involved in metanephros morphogenesisGO:000333740.018
hippocampus developmentGO:002176610.018
epithelial cell developmentGO:0002064340.018
embryonic epithelial tube formationGO:000183840.018
regulation of cellular response to growth factor stimulusGO:0090287760.018
endoderm developmentGO:0007492330.018
positive regulation of neuron differentiationGO:0045666400.018
single organism carbohydrate metabolic processGO:00447231930.018
positive regulation of purine nucleotide catabolic processGO:00331231850.018
regulation of homeostatic processGO:00328441210.018
sodium ion transmembrane transportGO:0035725590.018
response to nitrogen compoundGO:19016981840.018
positive regulation of nucleotide metabolic processGO:00459812300.018
sequestering of metal ionGO:0051238240.018
protein processingGO:00164852260.018
regulation of response to woundingGO:19030341010.018
thymus developmentGO:004853830.018
cell differentiation in spinal cordGO:002151510.018
actin cytoskeleton organizationGO:00300362070.018

ZIC3 disease predictions

DiseaseDO term IDSizeProbabilityFunc Analog Org
sensory system diseaseDOID:00501552030.067
nervous system diseaseDOID:8634310.067
eye diseaseDOID:56141490.060
eye and adnexa diseaseDOID:14921500.060
musculoskeletal system diseaseDOID:172230.025
bone diseaseDOID:0080001880.025
connective tissue diseaseDOID:651090.025
retinal diseaseDOID:56791180.023
central nervous system diseaseDOID:3311860.020