Homo sapiens

99 known processes

MCL1

myeloid cell leukemia sequence 1 (BCL2-related)

(Aliases: BCL2L3,MCL1S,MCL1-ES,mcl1/EAT,MGC104264,Mcl-1,bcl2-L-3,MGC1839,MCL1L,EAT,TM)

MCL1 biological process predictions


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Biological processGO term IDProcess sizeProbabilityFunc Analog Org
neuron death in response to oxidative stressGO:003647591.000
mitochondrial membrane organizationGO:0007006401.000
Human
positive regulation of cellular response to oxidative stressGO:190040970.999
regulation of oxidative stress induced neuron deathGO:190320390.999
positive regulation of fibroblast apoptotic processGO:200027160.997
positive regulation of endoplasmic reticulum unfolded protein responseGO:190010340.996
Human
modulation by virus of host morphology or physiologyGO:0019048100.996
Human
positive regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathwayGO:190103030.996
fibroblast apoptotic processGO:004434680.995
regulation of mitochondrial membrane permeability involved in apoptotic processGO:1902108180.995
neuron intrinsic apoptotic signaling pathway in response to oxidative stressGO:003648070.992
intrinsic apoptotic signaling pathwayGO:00971931270.990
positive regulation of response to oxidative stressGO:190288470.989
positive regulation of oxidative stress induced cell deathGO:190320950.989
positive regulation of release of cytochrome c from mitochondriaGO:0090200180.988
Human
positive regulation of mitochondrion organizationGO:0010822300.988
Human Worm
response to endoplasmic reticulum stressGO:0034976490.981
Human
regulation of apoptotic dna fragmentationGO:190251030.979
Human
regulation of oxidative stress induced cell deathGO:1903201240.979
positive regulation of oxidative stress induced neuron intrinsic apoptotic signaling pathwayGO:190337820.975
modulation of programmed cell death in other organism involved in symbiotic interactionGO:005224810.971
Human
apoptotic mitochondrial changesGO:0008637570.968
Human Mouse
negative regulation of extrinsic apoptotic signaling pathway in absence of ligandGO:2001240160.967
activation of cysteine type endopeptidase activity involved in apoptotic process by cytochrome cGO:000863520.967
Human
positive regulation of oxidative stress induced intrinsic apoptotic signaling pathwayGO:190217740.961
negative regulation of apoptotic processGO:00430663160.960
regulation of cellular response to oxidative stressGO:1900407260.960
protein insertion into mitochondrial membrane involved in apoptotic signaling pathwayGO:000184420.958
positive regulation of mitochondrial membrane permeabilityGO:0035794170.957
positive regulation of cysteine type endopeptidase activityGO:2001056790.956
Human
regulation of extrinsic apoptotic signaling pathway in absence of ligandGO:2001239200.955
positive regulation of peptidase activityGO:0010952880.954
Human
negative regulation of programmed cell deathGO:00430693210.952
mitochondrial outer membrane permeabilization involved in programmed cell deathGO:1902686160.952
nucleic acid phosphodiester bond hydrolysisGO:00903051020.942
Human
zymogen activationGO:0031638700.940
Human
cellular response to hypoxiaGO:0071456510.935
positive regulation of apoptotic processGO:00430652460.929
endoplasmic reticulum unfolded protein responseGO:0030968160.928
Human
establishment or maintenance of transmembrane electrochemical gradientGO:001024820.928
Human
positive regulation of cysteine type endopeptidase activity involved in apoptotic processGO:0043280690.923
Human
immune response activating signal transductionGO:0002757900.918
Human
release of cytochrome c from mitochondriaGO:0001836350.918
Human
intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stressGO:0070059120.915
Human
fibroblast proliferationGO:0048144330.914
positive regulation of protein oligomerizationGO:0032461170.901
Human
regulation of protein heterodimerization activityGO:004349750.891
Human
protein maturationGO:00516042330.888
Human Zebrafish
t cell homeostasisGO:004302930.885
regulation of execution phase of apoptosisGO:1900117110.884
Human
cell type specific apoptotic processGO:00972851250.882
defense responseGO:00069523150.876
Human
apoptotic process involved in morphogenesisGO:006056130.868
positive regulation of mitochondrial membrane permeability involved in apoptotic processGO:1902110160.867
positive regulation of intrinsic apoptotic signaling pathwayGO:2001244280.867
protein ubiquitinationGO:00165673140.866
Human
regulation of intrinsic apoptotic signaling pathwayGO:2001242720.866
regulation of mitochondrial membrane permeabilityGO:0046902250.865
Human
intrinsic apoptotic signaling pathway in response to dna damageGO:0008630500.862
Human Mouse
activation of immune responseGO:00022531140.862
Human
viral processGO:00160321460.862
Human
response to external biotic stimulusGO:00432072610.859
Human
regulation of oxidative stress induced neuron intrinsic apoptotic signaling pathwayGO:190337670.858
response to uvGO:0009411730.857
Human
lymphocyte homeostasisGO:000226040.855
leukocyte apoptotic processGO:0071887310.850
Human
interspecies interaction between organismsGO:00444191560.850
Human
regulation of mitochondrion organizationGO:0010821540.850
Human Worm
protein localization to membraneGO:00726571600.847
Human
cellular response to dna damage stimulusGO:00069743790.845
response to organic cyclic compoundGO:00140702040.840
Human
intrinsic apoptotic signaling pathway in response to oxidative stressGO:0008631210.839
membrane organizationGO:00610242920.838
Human Worm
fear responseGO:004259600.831
regulation of mitochondrial membrane potentialGO:0051881230.831
Human
execution phase of apoptosisGO:0097194320.828
Human
modulation by symbiont of host programmed cell deathGO:005204010.826
Human
mitochondrial outer membrane permeabilizationGO:0097345150.823
protein modification by small protein conjugationGO:00324463420.823
Human
protein polyubiquitinationGO:00002091100.820
Human
modulation by virus of host processGO:001905420.816
Human
modulation of apoptotic process in other organismGO:004453210.810
Human
mitochondrial fragmentation involved in apoptotic processGO:004365370.809
Human
lymphocyte apoptotic processGO:0070227200.801
Human
multi organism cellular processGO:00447641560.799
Human
mitochondrion organizationGO:00070051560.798
Human Mouse Worm
regulation of endopeptidase activityGO:00525481700.797
Human Zebrafish
regulation of membrane permeabilityGO:0090559250.776
Human
mitotic cell cycle phase transitionGO:00447721620.765
Human
regulation of peptidase activityGO:00525471800.765
Human Zebrafish
regulation of establishment of protein localizationGO:00702012420.765
Human
reactive oxygen species metabolic processGO:0072593750.762
response to virusGO:00096151260.758
Human
cellular response to topologically incorrect proteinGO:0035967190.757
Human
positive regulation of oxidative stress induced neuron deathGO:190322320.756
post embryonic developmentGO:000979120.756
positive regulation of neuron apoptotic processGO:004352580.746
response to nitrogen compoundGO:19016981840.743
Human
positive regulation of apoptotic signaling pathwayGO:2001235700.742
negative regulation by organism of programmed cell death in other organism involved in symbiotic interactionGO:005249010.736
Human
regulation of response to dna damage stimulusGO:2001020940.734
response to cytokineGO:00340972320.730
purine ribonucleoside metabolic processGO:00461284370.715
Worm
neuron apoptotic processGO:0051402390.714
negative regulation of execution phase of apoptosisGO:190011860.712
Human
protein processingGO:00164852260.711
Human Zebrafish
negative regulation of cell proliferationGO:00082852280.692
hematopoietic or lymphoid organ developmentGO:00485341860.686
response to biotic stimulusGO:00096072760.683
Human
membrane fusionGO:0061025430.683
Human Worm
modulation by symbiont of host apoptotic processGO:005215010.683
Human
defense response to virusGO:0051607710.671
Human
symbiosis encompassing mutualism through parasitismGO:00444031560.668
Human
modulation by symbiont of host cellular processGO:004406830.666
Human
positive regulation of neuron deathGO:1901216140.655
transformed cell apoptotic processGO:000692730.654
Human
regulation of protein localization to plasma membraneGO:1903076400.654
Human
blood vessel morphogenesisGO:00485141620.647
regulation of intracellular phGO:0051453160.644
Human
er nucleus signaling pathwayGO:0006984230.637
Human
negative regulation of apoptotic signaling pathwayGO:2001234970.632
regulation of endoplasmic reticulum unfolded protein responseGO:190010150.628
Human
b cell homeostasisGO:000178210.625
regulation of oxidative stress induced intrinsic apoptotic signaling pathwayGO:1902175160.604
mitotic cell cycleGO:00002783260.604
Human Zebrafish
single organism membrane organizationGO:00448022680.603
Human Worm
positive regulation of programmed cell deathGO:00430682490.602
modulation by organism of apoptotic process in other organism involved in symbiotic interactionGO:005243310.594
Human
cellular response to external stimulusGO:00714961110.591
Human
thymus developmentGO:004853830.588
extrinsic apoptotic signaling pathwayGO:00971911190.584
cd4 positive or cd8 positive alpha beta t cell lineage commitmentGO:004336910.581
regulation of cellular ph reductionGO:003284710.578
Human
establishment of protein localization to membraneGO:00901501210.577
Human
response to abiotic stimulusGO:00096283360.576
Human
modification of morphology or physiology of other organismGO:0035821430.576
Human
regulation of membrane potentialGO:0042391950.564
Human
negative regulation of cell cycleGO:00457861930.559
Human Zebrafish
regulation of proteolysisGO:00301622930.558
Human Zebrafish
regulation of cellular response to stressGO:00801352440.557
regulation of neuron apoptotic processGO:0043523350.557
positive regulation of endopeptidase activityGO:0010950840.542
Human
positive regulation of hydrolase activityGO:00513453310.538
Human Worm
positive regulation of protein complex assemblyGO:0031334860.537
Human
apoptotic signaling pathwayGO:00971902680.533
cell death in response to oxidative stressGO:0036473290.510
regulation of protein complex assemblyGO:00432541470.506
Human
protein insertion into mitochondrial membraneGO:005120430.502
positive regulation of leukocyte proliferationGO:0070665480.499
Human
positive regulation of developmental processGO:00510943140.497
Worm
cell cycle phase transitionGO:00447701730.489
Human
negative regulation of protein metabolic processGO:00512483910.489
Zebrafish
endomembrane system organizationGO:00102561960.488
Human
modulation of programmed cell death in other organismGO:004453110.484
Human
activation of cysteine type endopeptidase activity involved in apoptotic processGO:0006919490.482
Human
purine ribonucleotide catabolic processGO:00091544040.480
Worm
negative regulation of signal transduction in absence of ligandGO:1901099160.480
neuron projection regenerationGO:003110210.476
neuron deathGO:0070997650.472
regulation of growthGO:00400081650.463
Human
regulation of cell motilityGO:20001452990.459
positive regulation of immune system processGO:00026842830.459
Human
response to radiationGO:00093141510.453
Human
protein catabolic processGO:00301633250.448
negative regulation of cell differentiationGO:00455961710.447
cellular response to oxidative stressGO:0034599850.442
mitochondrial transportGO:0006839600.436
Human
regulation of protein localizationGO:00328802960.436
Human
intrinsic apoptotic signaling pathway by p53 class mediatorGO:0072332370.436
positive regulation of intracellular transportGO:00323881040.433
apoptotic dna fragmentationGO:000630960.432
Human
positive regulation of cytosolic calcium ion concentrationGO:0007204820.422
regulation of mitotic cell cycle phase transitionGO:19019901180.413
Human
positive regulation of extrinsic apoptotic signaling pathwayGO:2001238260.410
negative regulation of cell deathGO:00605483450.408
regulation of fibroblast apoptotic processGO:200026980.404
regulation of calcium ion transportGO:0051924790.400
Human
positive regulation of pigment cell differentiationGO:005094220.399
regulation of anoikisGO:2000209190.394
negative regulation of organelle organizationGO:00106391260.393
Human Zebrafish
regulation of cell migrationGO:00303342890.392
positive regulation of cell deathGO:00109422630.392
immune response activating cell surface receptor signaling pathwayGO:0002429450.390
Human
regulation of b cell activationGO:0050864240.388
Human
positive regulation of apoptotic dna fragmentationGO:190251210.382
Human
thymocyte apoptotic processGO:007024220.380
carbohydrate metabolic processGO:00059752070.380
response to cycloheximideGO:004689810.373
negative regulation of calcium ion transport into cytosolGO:001052330.366
regulation of cellular carbohydrate metabolic processGO:0010675470.366
organelle fusionGO:0048284360.363
Human Worm
regulation of extrinsic apoptotic signaling pathwayGO:2001236850.360
homeostasis of number of cellsGO:0048872400.355
protein oligomerizationGO:00512591730.339
Human
glycosyl compound catabolic processGO:19016584130.339
Worm
cell divisionGO:00513011680.337
Human Zebrafish
cytoplasmic transportGO:00164823790.333
regulation of cysteine type endopeptidase activityGO:20001161270.328
Human Zebrafish
protein localization to mitochondrionGO:0070585250.325
regulation of protein oligomerizationGO:0032459260.323
Human
response to reactive oxygen speciesGO:0000302610.316
cell cycle checkpointGO:00000751170.314
Human
regulation of fibroblast proliferationGO:0048145320.312
regulation of apoptotic signaling pathwayGO:20012331750.311
activation of cysteine type endopeptidase activityGO:0097202570.308
Human
regulation of reactive oxygen species metabolic processGO:2000377410.308
kidney developmentGO:0001822530.305
response to light stimulusGO:0009416870.304
Human
leukocyte homeostasisGO:000177670.302
regulation of cell cycleGO:00517263930.299
Human Zebrafish
response to oxygen levelsGO:00704821000.297
anoikisGO:0043276220.296
response to oxygen containing compoundGO:19017003690.296
post embryonic organ developmentGO:004856910.295
nucleoside triphosphate metabolic processGO:00091414220.292
Worm
positive regulation of extrinsic apoptotic signaling pathway via death domain receptorsGO:190204330.292
regulation of homeostatic processGO:00328441210.288
Human
response to other organismGO:00517072610.284
Human
dna catabolic processGO:0006308490.282
Human
regulation of developmental pigmentationGO:004807020.280
positive regulation of muscle cell differentiationGO:0051149150.276
positive regulation of b cell proliferationGO:0030890120.276
Human
regulation of cellular amino acid metabolic processGO:000652160.276
regulation of cell cycle processGO:00105642660.275
Human Zebrafish
amine metabolic processGO:0009308440.275
calcium ion transportGO:00068161470.267
Human
negative regulation of mitotic cell cycle phase transitionGO:1901991850.263
Human
positive regulation of proteolysisGO:00458621420.262
Human
purine ribonucleoside triphosphate metabolic processGO:00092054110.260
Worm
negative regulation of fibroblast proliferationGO:0048147120.257
regulation of cysteine type endopeptidase activity involved in apoptotic processGO:00432811160.253
Human Zebrafish
regulation of symbiosis encompassing mutualism through parasitismGO:00439031090.248
protein deubiquitinationGO:0016579790.248
regulation of release of cytochrome c from mitochondriaGO:0090199290.246
Human
establishment of protein localization to mitochondrionGO:0072655220.240
immune responseGO:00069553070.238
Human
establishment of protein localization to organelleGO:00725941720.236
positive regulation of developmental pigmentationGO:004808720.236
organophosphate catabolic processGO:00464344300.235
Worm
cellular amine metabolic processGO:0044106410.235
positive regulation of dna catabolic processGO:190362620.234
Human
ribonucleoside triphosphate metabolic processGO:00091994120.233
Worm
negative regulation by symbiont of host programmed cell deathGO:005204110.233
Human
modification by symbiont of host morphology or physiologyGO:0044003120.226
Human
multicellular organismal agingGO:001025930.226
cell developmentGO:00484683280.221
single organism cellular localizationGO:19025803320.221
Human
urogenital system developmentGO:0001655650.221
regulation of mitochondrial fusionGO:001063550.220
Worm
immune response regulating signaling pathwayGO:0002764970.219
Human
negative regulation of cellular protein metabolic processGO:00322693530.218
Zebrafish
negative regulation of cellular component organizationGO:00511292350.218
Human Zebrafish
anatomical structure formation involved in morphogenesisGO:00486462840.217
proteasomal protein catabolic processGO:00104981760.216
limbic system developmentGO:002176130.215
t cell apoptotic processGO:0070231120.214
regulation of metal ion transportGO:00109591200.213
Human
response to oxidative stressGO:00069791210.210
negative regulation of cell cycle phase transitionGO:1901988890.210
Human
cellular component disassemblyGO:0022411920.208
Human
negative regulation of anoikisGO:2000811150.206
response to topologically incorrect proteinGO:0035966290.205
Human
cellular macromolecule catabolic processGO:00442653800.202
Human
proteolysis involved in cellular protein catabolic processGO:00516032440.198
response to inorganic substanceGO:00100351270.198
Human
nucleotide catabolic processGO:00091664080.195
Worm
regulation of response to oxidative stressGO:1902882260.188
osteoblast proliferationGO:003368780.188
positive regulation of reactive oxygen species metabolic processGO:2000379240.186
ribonucleoside catabolic processGO:00424544060.186
Worm
response to woundingGO:00096111680.185
positive regulation of cellular component organizationGO:00511303760.183
Human Worm
regenerationGO:003109940.180
cellular response to starvationGO:0009267580.179
positive regulation of protein homooligomerizationGO:003246470.177
response to glucocorticoidGO:0051384130.175
response to iron ionGO:001003960.175
Human
protein k48 linked ubiquitinationGO:0070936380.172
ribonucleotide catabolic processGO:00092614050.172
Worm
positive regulation of killing of cells of other organismGO:005171240.172
positive regulation of apoptotic process involved in mammary gland involutionGO:006005810.170
regulation of killing of cells of other organismGO:005170940.166
rna processingGO:00063962550.163
purine ribonucleoside triphosphate catabolic processGO:00092073910.162
Worm
negative regulation of cell cycle processGO:00109481210.162
Human Zebrafish
regulation of intracellular transportGO:00323861950.162
cellular response to unfolded proteinGO:0034620160.160
Human
intrinsic apoptotic signaling pathway in response to dna damage by p53 class mediatorGO:0042771230.159
negative regulation of mitotic cell cycleGO:00459301020.156
Human Zebrafish
dna damage response signal transduction by p53 class mediatorGO:0030330440.154
immune response regulating cell surface receptor signaling pathwayGO:0002768510.153
Human
antigen receptor mediated signaling pathwayGO:0050851380.152
Human
glucose metabolic processGO:0006006450.150
multicellular organismal response to stressGO:003355510.150
vasculature developmentGO:00019441810.150
regulation of neuron deathGO:1901214560.149
organ morphogenesisGO:00098871470.149
cellular lipid metabolic processGO:00442553030.149
negative regulation of proteolysisGO:00458611320.147
Zebrafish
response to extracellular stimulusGO:0009991850.145
response to electrical stimulusGO:005160210.145
hair follicle morphogenesisGO:003106920.144
regulation of immune responseGO:00507762010.141
Human
mitotic cell cycle checkpointGO:0007093680.141
Human
regulation of cell cycle phase transitionGO:19019871260.141
Human
positive regulation of execution phase of apoptosisGO:190011950.141
Human
nucleocytoplasmic transportGO:00069131760.140
regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathwayGO:190102890.139
regulation of b cell proliferationGO:0030888180.136
Human
regulation of cell maturationGO:190342930.134
response to ionizing radiationGO:0010212650.133
cytosolic calcium ion homeostasisGO:0051480890.132
nucleoside phosphate catabolic processGO:19012924120.132
Worm
negative regulation of phosphate metabolic processGO:00459362670.130
regulation of lymphocyte apoptotic processGO:0070228150.130
purine ribonucleoside catabolic processGO:00461303980.128
Worm
regulation of cell growthGO:00015581350.127
Human
negative regulation of mitochondrion organizationGO:0010823220.127
Human
t cell activationGO:0042110990.126
positive regulation of apoptotic process involved in morphogenesisGO:190233910.125
protein homooligomerizationGO:00512601000.125
Human
immune effector processGO:00022521590.123
Human
lymphocyte proliferationGO:0046651700.123
Human
regulation of transferase activityGO:00513383550.122
single organism carbohydrate metabolic processGO:00447231930.122
muscle cell differentiationGO:0042692630.121
regulation of carbohydrate metabolic processGO:0006109540.120
behavioral defense responseGO:000220900.119
regulation of cellular component sizeGO:0032535820.117
regulation of intrinsic apoptotic signaling pathway in response to dna damageGO:1902229200.116
Human
cell adhesionGO:00071553250.115
rna phosphodiester bond hydrolysisGO:0090501350.113
positive regulation of lymphocyte proliferationGO:0050671460.110
Human
response to mechanical stimulusGO:0009612510.110
Human
posttranscriptional regulation of gene expressionGO:00106082130.108
negative regulation of intrinsic apoptotic signaling pathwayGO:2001243400.108
Human
regulation of viral processGO:00507921030.107
cardiovascular system developmentGO:00723582620.104
divalent metal ion transportGO:00708381520.102
Human
negative regulation of protein maturationGO:19033181420.101
Zebrafish
nuclear divisionGO:00002801280.100
Zebrafish
regulation of ion homeostasisGO:2000021730.099
Human
ribonucleoside triphosphate catabolic processGO:00092033910.098
Worm
response to drugGO:0042493810.098
Human
cell growthGO:00160491600.098
Human
ncrna metabolic processGO:00346601080.096
development of primary male sexual characteristicsGO:0046546230.096
hemopoiesisGO:00300971800.095
developmental pigmentationGO:0048066120.095
generation of neuronsGO:00486991520.095
extrinsic apoptotic signaling pathway in absence of ligandGO:0097192220.095
cell projection organizationGO:00300302520.094
positive regulation of cell growthGO:0030307480.093
Human
regulation of myeloid cell differentiationGO:0045637810.092
negative regulation of protein modification processGO:00314002000.092
oogenesisGO:004847720.091
cellular component disassembly involved in execution phase of apoptosisGO:0006921130.091
Human
hexose metabolic processGO:0019318550.091
response to dsrnaGO:0043331250.091
response to hypoxiaGO:0001666960.088
regulation of protein bindingGO:0043393660.088
Human
positive regulation of dna metabolic processGO:0051054730.088
Human
response to gamma radiationGO:0010332140.088
positive regulation of homeostatic processGO:0032846470.088
response to organonitrogen compoundGO:00102431560.088
Human
dna catabolic process endonucleolyticGO:0000737370.086
Human
regulation of response to external stimulusGO:00321012220.085
growthGO:00400072020.084
Human
patterning of blood vesselsGO:000156920.084
mrna metabolic processGO:00160711750.083
cytokinesisGO:0000910960.082
Human
negative regulation of transcription from rna polymerase ii promoterGO:00001222810.081
viral life cycleGO:00190581320.081
regulation of neuron differentiationGO:0045664700.081
b cell proliferationGO:0042100220.080
Human
response to organophosphorusGO:0046683410.080
immune system developmentGO:00025201950.079
monosaccharide metabolic processGO:0005996740.079
myeloid cell differentiationGO:00300991170.078
response to axon injuryGO:004867810.077
peptidyl tyrosine dephosphorylationGO:0035335360.077
positive regulation of signal transduction by p53 class mediatorGO:1901798100.077
regulation of leukocyte apoptotic processGO:2000106250.077
mitochondrial fusionGO:0008053130.077
Human Worm
regulation of anatomical structure sizeGO:00900661010.077
male gonad developmentGO:0008584230.077
cellular response to decreased oxygen levelsGO:0036294510.076
cellular ion homeostasisGO:00068731680.075
Human
protein insertion into membraneGO:005120590.075
metencephalon developmentGO:002203720.074
rhythmic processGO:0048511310.074
b cell apoptotic processGO:000178360.074
Human
regulation of cellular amine metabolic processGO:0033238110.073
negative regulation of protein bindingGO:0032091350.073
Human
regulation of dna metabolic processGO:00510521530.073
Human
rna 5 end processingGO:000096620.073
cellular amino acid metabolic processGO:00065201160.072
response to purine containing compoundGO:0014074400.072
regulation of cellular component movementGO:00512703340.071
cell activationGO:00017752130.071
Human
regulation of cell differentiationGO:00455953930.071
regulation of apoptotic process involved in morphogenesisGO:190233710.071
regulation of mitotic cell cycleGO:00073461890.070
Human Zebrafish
cellular protein catabolic processGO:00442572610.069
leukocyte proliferationGO:0070661740.069
Human
response to unfolded proteinGO:0006986240.069
Human
cellular carbohydrate metabolic processGO:0044262840.069
regulation of cell activationGO:00508651250.069
Human
positive regulation of cell migrationGO:00303351720.068
regulation of cellular component biogenesisGO:00440872810.068
Human
ossificationGO:00015031210.067
negative regulation of extrinsic apoptotic signaling pathwayGO:2001237520.067
response to nitrosative stressGO:005140940.066
tube developmentGO:00352951250.065
negative regulation of chemokine c x c motif ligand 2 productionGO:200034210.065
negative regulation of transportGO:00510511760.064
negative regulation of cellular amine metabolic processGO:003323930.063
positive regulation of dna damage response signal transduction by p53 class mediatorGO:004351780.063
positive regulation of transportGO:00510503360.063
sequestering of calcium ionGO:0051208170.062
regulation of b cell apoptotic processGO:000290250.062
guanosine containing compound metabolic processGO:19010682440.062
Worm
cation transportGO:00068123310.062
Human
regulation of cellular ketone metabolic processGO:0010565500.062
nitrogen compound transportGO:00717051910.061
regulation of anatomical structure morphogenesisGO:00226032860.061
Worm
response to hydrogen peroxideGO:0042542400.061
nucleus organizationGO:0006997280.061
enzyme linked receptor protein signaling pathwayGO:00071673030.061
behavioral fear responseGO:000166200.061
pigment granule organizationGO:004875370.061
regulation of bindingGO:00510981110.060
Human
regulation of establishment of protein localization to plasma membraneGO:0090003300.060
Human
pigmentationGO:0043473220.060
cellular response to light stimulusGO:0071482340.060
Human
determination of adult lifespanGO:000834020.060
cellular homeostasisGO:00197251960.059
Human
maturation of ssu rrnaGO:003049030.059
spleen developmentGO:004853610.059
regulation of mononuclear cell proliferationGO:0032944650.059
Human
ovulation cycle processGO:002260290.058
anatomical structure homeostasisGO:00602491000.058
Zebrafish
cellular divalent inorganic cation homeostasisGO:00725031280.058
response to decreased oxygen levelsGO:0036293960.058
apoptotic process in bone marrowGO:007183910.057
regulation of gtp catabolic processGO:00331241800.057
Worm
regulation of multi organism processGO:00439001570.056
gtp metabolic processGO:00460392390.056
Worm
negative regulation of intracellular signal transductionGO:19025321830.056
Human
positive regulation of organelle organizationGO:00106381950.056
Human Worm
male sex differentiationGO:0046661250.055
regulation of peptidyl serine phosphorylationGO:0033135500.055
positive regulation of cellular component biogenesisGO:00440891580.055
Human
regulation of lymphocyte proliferationGO:0050670640.055
Human
regulation of extrinsic apoptotic signaling pathway via death domain receptorsGO:1902041240.055
ribosomal small subunit biogenesisGO:0042274130.055
muscle tissue developmentGO:0060537620.054
modification of morphology or physiology of other organism involved in symbiotic interactionGO:0051817380.054
Human
regulation of response to woundingGO:19030341010.054
purine nucleoside triphosphate catabolic processGO:00091463920.054
Worm
response to nutrient levelsGO:0031667810.054
interaction with hostGO:0051701420.054
Human
retinal cell apoptotic processGO:199000910.053
Human
negative regulation of transferase activityGO:00513481240.053
nucleoside triphosphate catabolic processGO:00091433940.053
Worm
reactive nitrogen species metabolic processGO:200105730.052
oxidation reduction processGO:00551143960.052
regulation of nucleoside metabolic processGO:00091182090.052
Worm
negative regulation of systemic arterial blood pressureGO:000308510.052
single organism membrane fusionGO:0044801370.052
Human Worm
cellular response to uvGO:0034644320.051
Human
ribonucleoside monophosphate catabolic processGO:00091581580.051
biological adhesionGO:00226103310.050
striated muscle tissue developmentGO:0014706590.050
erk1 and erk2 cascadeGO:00703711040.050
negative regulation of cellular amino acid metabolic processGO:004576320.050
regulation of dna catabolic processGO:190362470.050
Human
inflammatory responseGO:0006954790.049
spermatid differentiationGO:004851540.049
mononuclear cell proliferationGO:0032943710.049
Human
t cell selectionGO:004505840.048
multicellular organismal homeostasisGO:0048871670.048
Zebrafish
guanosine containing compound catabolic processGO:19010692390.047
Worm
developmental programmed cell deathGO:001062330.046
blood vessel developmentGO:00015681720.046
response to starvationGO:0042594590.046
cellular response to glucose starvationGO:004214980.046
maturation of 5 8s rrna from tricistronic rrna transcript ssu rrna 5 8s rrna lsu rrna GO:000046620.046
maturation of lsu rrna from tricistronic rrna transcript ssu rrna 5 8s rrna lsu rrna GO:000046330.045
actin cytoskeleton organizationGO:00300362070.045
negative regulation of protein processingGO:00109551420.045
Zebrafish
protein modification by small protein removalGO:0070646920.045
regulation of leukocyte activationGO:00026941150.044
Human
rhythmic behaviorGO:000762220.044
positive regulation of gtpase activityGO:00435471660.044
Worm

MCL1 disease predictions

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of cellular proliferationDOID:145661740.158
Human
organ system cancerDOID:00506861640.148
Human
cancerDOID:1621670.148
Human
gastrointestinal system cancerDOID:3119520.148
Human