Homo sapiens

38 known processes

FTH1

ferritin, heavy polypeptide 1

(Aliases: MGC104426,FHC,PIG15,PLIF,FTH,FTHL6)

FTH1 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
cellular iron ion homeostasisGO:000687980.734
determination of adult lifespanGO:000834020.731
Worm
response to bacteriumGO:00096171440.711
Worm
cellular cation homeostasisGO:00300031630.678
cellular ion homeostasisGO:00068731680.676
cellular transition metal ion homeostasisGO:0046916210.653
ion homeostasisGO:00508012300.558
chemical homeostasisGO:00488783060.465
defense responseGO:00069523150.444
Worm
fibroblast proliferationGO:0048144330.417
defense response to gram positive bacteriumGO:0050830290.399
Worm
defense response to other organismGO:00985421290.390
Worm
negative regulation of fibroblast proliferationGO:0048147120.383
cellular response to oxidative stressGO:0034599850.340
cellular response to oxygen containing compoundGO:19017012760.318
cellular chemical homeostasisGO:00550821800.316
response to biotic stimulusGO:00096072760.298
Worm
response to inorganic substanceGO:00100351270.278
epithelial cell differentiationGO:00308551410.245
protein deubiquitinationGO:0016579790.229
defense response to bacteriumGO:0042742630.228
Worm
positive regulation of phosphorylationGO:00423273940.215
regulation of i kappab kinase nf kappab signalingGO:00431221620.204
i kappab kinase nf kappab signalingGO:00072491660.200
regulation of defense responseGO:00313471540.188
negative regulation of apoptotic signaling pathwayGO:2001234970.181
sequestering of metal ionGO:0051238240.178
positive regulation of immune system processGO:00026842830.168
cofactor metabolic processGO:0051186870.163
response to external biotic stimulusGO:00432072610.159
Worm
g protein coupled receptor signaling pathway coupled to cyclic nucleotide second messengerGO:0007187430.155
response to oxygen containing compoundGO:19017003690.150
maintenance of locationGO:00512351120.139
innate immune responseGO:00450871780.134
response to other organismGO:00517072610.123
Worm
multicellular organismal agingGO:001025930.115
Worm
regulation of apoptotic signaling pathwayGO:20012331750.107
response to nitrogen compoundGO:19016981840.102
cytokine productionGO:00018162470.101
regulation of rubidium ion transportGO:200068030.100
response to cytokineGO:00340972320.100
positive regulation of i kappab kinase nf kappab signalingGO:00431231320.090
reactive oxygen species metabolic processGO:0072593750.090
transition metal ion homeostasisGO:0055076310.089
negative regulation of cellular response to oxidative stressGO:1900408180.087
negative regulation of immune system processGO:00026831360.082
hematopoietic or lymphoid organ developmentGO:00485341860.080
protein modification by small protein removalGO:0070646920.080
multicellular organismal homeostasisGO:0048871670.079
negative regulation of extrinsic apoptotic signaling pathwayGO:2001237520.077
apoptotic signaling pathwayGO:00971902680.077
cellular response to endogenous stimulusGO:00714953360.073
chromatin organizationGO:00063253510.072
negative regulation of apoptotic processGO:00430663160.072
retina homeostasisGO:0001895420.072
positive regulation of immune responseGO:00507781590.069
immune response activating signal transductionGO:0002757900.069
epithelium developmentGO:00604292270.069
mapk cascadeGO:00001652880.068
detection of chemical stimulusGO:0009593550.068
regulation of cytokine productionGO:00018172320.067
cell adhesionGO:00071553250.064
response to decreased oxygen levelsGO:0036293960.063
endosomal transportGO:00161971290.062
chemokine productionGO:0032602320.062
negative regulation of cell deathGO:00605483450.062
response to reactive oxygen speciesGO:0000302610.061
peptidyl lysine modificationGO:00182051440.058
protein polyubiquitinationGO:00002091100.057
negative regulation of multicellular organismal processGO:00512413170.057
response to organonitrogen compoundGO:00102431560.056
detection of stimulusGO:0051606850.056
regulation of ion transportGO:00432691890.055
reactive nitrogen species metabolic processGO:200105730.054
prostate gland developmentGO:003085030.053
ubiquitin dependent protein catabolic processGO:00065112060.052
negative regulation of phosphorus metabolic processGO:00105632670.052
cellular modified amino acid metabolic processGO:0006575640.052
oxidation reduction processGO:00551143960.052
positive regulation of cellular component organizationGO:00511303760.051
regulation of reactive oxygen species biosynthetic processGO:190342630.050
extrinsic apoptotic signaling pathway via death domain receptorsGO:0008625420.050
response to hydrogen peroxideGO:0042542400.050
sensory perception of sweet tasteGO:005091620.050
regulation of cellular response to stressGO:00801352440.049
cell activationGO:00017752130.049
protein ubiquitinationGO:00165673140.049
positive regulation of dna templated transcription elongationGO:0032786180.048
negative regulation of defense responseGO:0031348470.048
negative regulation of chemokine productionGO:003268290.048
negative regulation of cell proliferationGO:00082852280.047
snrna transcriptionGO:000930180.047
covalent chromatin modificationGO:00165692540.047
growthGO:00400072020.045
post embryonic developmentGO:000979120.045
cytoplasmic transportGO:00164823790.045
regulation of sequence specific dna binding transcription factor activityGO:00510902110.044
cellular ketone metabolic processGO:0042180800.044
negative regulation of oxidative stress induced cell deathGO:1903202170.044
regulation of cell differentiationGO:00455953930.043
protein localization to organelleGO:00333652800.043
immune responseGO:00069553070.042
myd88 independent toll like receptor signaling pathwayGO:000275620.042
negative regulation of cellular protein metabolic processGO:00322693530.041
cation transportGO:00068123310.041
negative regulation of catalytic activityGO:00430863350.041
antigen processing and presentation via mhc class ibGO:000247530.040
response to abiotic stimulusGO:00096283360.040
protein homooligomerizationGO:00512601000.040
regulation of extrinsic apoptotic signaling pathwayGO:2001236850.040
regulation of transferase activityGO:00513383550.039
positive regulation of t cell tolerance inductionGO:000266620.039
negative regulation of protein modification processGO:00314002000.039
response to growth factorGO:00708482050.039
response to thyroid hormoneGO:009706690.038
tissue homeostasisGO:0001894630.038
chromatin assembly or disassemblyGO:0006333780.038
cell type specific apoptotic processGO:00972851250.037
immune effector processGO:00022521590.037
protein modification by small protein conjugationGO:00324463420.037
negative regulation of intracellular signal transductionGO:19025321830.037
response to peptideGO:1901652650.036
regulation of peptidase activityGO:00525471800.036
signal transduction by phosphorylationGO:00230142970.035
detection of external biotic stimulusGO:0098581190.035
regulation of proteasomal protein catabolic processGO:0061136870.035
autophagyGO:0006914880.035
regulation of kinase activityGO:00435493140.035
protein oligomerizationGO:00512591730.035
nucleoside phosphate biosynthetic processGO:19012931090.035
positive regulation of purine nucleotide metabolic processGO:19005442270.035
extrinsic apoptotic signaling pathwayGO:00971911190.034
vesicle mediated transportGO:00161923710.034
regulation of response to external stimulusGO:00321012220.034
regulation of immune responseGO:00507762010.034
response to oxidative stressGO:00069791210.033
nucleotide biosynthetic processGO:00091651090.033
oxidoreduction coenzyme metabolic processGO:0006733190.033
organic hydroxy compound metabolic processGO:19016151470.033
regulation of membrane potentialGO:0042391950.032
positive regulation of catabolic processGO:00098963100.032
positive regulation of defense responseGO:0031349870.031
regulation of innate immune responseGO:0045088970.031
regulation of protein catabolic processGO:00421761550.030
cellular response to hypoxiaGO:0071456510.030
negative regulation of protein metabolic processGO:00512483910.029
apoptotic mitochondrial changesGO:0008637570.029
regulation of response to oxidative stressGO:1902882260.029
response to drugGO:0042493810.029
regulation of cellular ketone metabolic processGO:0010565500.029
regulation of microvillus assemblyGO:003253410.028
positive regulation of purine nucleotide biosynthetic processGO:1900373380.028
cellular response to metal ionGO:0071248430.028
positive regulation of protein catabolic processGO:0045732750.028
regulation of natural killer cell mediated cytotoxicityGO:0042269160.028
purine ribonucleotide catabolic processGO:00091544040.028
histone modificationGO:00165702510.027
protein autophosphorylationGO:00467771230.027
regulation of cellular response to oxidative stressGO:1900407260.027
monovalent inorganic cation transportGO:00156721280.027
regulation of cell activationGO:00508651250.027
regulation of cysteine type endopeptidase activity involved in apoptotic processGO:00432811160.027
transmembrane receptor protein tyrosine kinase signaling pathwayGO:00071691810.027
proteolysis involved in cellular protein catabolic processGO:00516032440.027
regulation of purine nucleotide metabolic processGO:19005422640.027
response to cadmium ionGO:0046686100.026
biological adhesionGO:00226103310.026
negative regulation of programmed cell deathGO:00430693210.026
negative regulation of nf kappab transcription factor activityGO:0032088510.026
regulation of exocytosisGO:0017157460.026
spermatid differentiationGO:004851540.025
positive regulation of protein kinase activityGO:00458601900.025
purine ribonucleoside triphosphate catabolic processGO:00092073910.024
dna repairGO:00062811980.024
regulation of protein maturationGO:19033171500.024
positive regulation of innate immune responseGO:0045089790.024
cellular response to reactive oxygen speciesGO:0034614500.024
immune system developmentGO:00025201950.024
cellular response to decreased oxygen levelsGO:0036294510.024
wound healingGO:00420601150.024
cellular amino acid metabolic processGO:00065201160.023
spermatid developmentGO:000728640.023
g protein coupled receptor signaling pathwayGO:00071862070.023
regulation of multi organism processGO:00439001570.023
negative regulation of hydrogen peroxide induced cell deathGO:190320690.023
mitotic cell cycle processGO:19030472860.022
immune response regulating signaling pathwayGO:0002764970.022
intrinsic apoptotic signaling pathwayGO:00971931270.022
response to radiationGO:00093141510.022
positive regulation of toll like receptor 4 signaling pathwayGO:003414560.022
regulation of nucleotide metabolic processGO:00061402690.022
positive regulation of interleukin 12 productionGO:003273580.022
regulation of immune effector processGO:0002697910.022
sensory perception of chemical stimulusGO:0007606380.022
myeloid cell differentiationGO:00300991170.022
epithelial cell migrationGO:00106311190.021
nucleoside phosphate catabolic processGO:19012924120.021
negative regulation of cytokine productionGO:0001818820.021
regulation of protein kinase activityGO:00458592890.021
iron ion homeostasisGO:0055072150.021
positive regulation of leukocyte activationGO:0002696800.021
protein acetylationGO:00064731160.021
proteasomal protein catabolic processGO:00104981760.021
positive regulation of kinase activityGO:00336742040.021
cellular response to organonitrogen compoundGO:00714171240.020
canonical wnt signaling pathwayGO:00600701160.020
regulation of proteolysis involved in cellular protein catabolic processGO:1903050910.020
anatomical structure homeostasisGO:00602491000.020
purine ribonucleoside metabolic processGO:00461284370.020
cellular response to growth factor stimulusGO:00713631970.020
regulation of stress activated protein kinase signaling cascadeGO:0070302850.019
negative regulation of epithelial cell migrationGO:0010633380.019
regulation of anatomical structure sizeGO:00900661010.019
regulation of integrin mediated signaling pathwayGO:200104430.019
cellular response to lipidGO:00713961270.019
cellular response to oxygen levelsGO:0071453550.019
cellular macromolecule catabolic processGO:00442653800.019
reproductive system developmentGO:0061458560.019
cellular response to abiotic stimulusGO:00712141170.019
regulation of hydrogen peroxide induced cell deathGO:1903205100.019
ribonucleotide catabolic processGO:00092614050.018
transition metal ion transportGO:0000041230.018
leukocyte activationGO:00453211640.018
protein k48 linked ubiquitinationGO:0070936380.018
cellular calcium ion homeostasisGO:00068741170.018
positive regulation of nitric oxide synthase biosynthetic processGO:005177030.018
negative regulation of cell differentiationGO:00455961710.018
pattern recognition receptor signaling pathwayGO:0002221480.018
dna conformation changeGO:00711031130.018
cellular response to nitrogen compoundGO:19016991440.018
transmembrane transportGO:00550853990.018
regulation of cell adhesionGO:00301551660.018
regulation of mitochondrion organizationGO:0010821540.018
leukocyte migrationGO:00509001070.018
cellular component morphogenesisGO:00329893140.018
regulation of vascular endothelial growth factor signaling pathwayGO:190074660.017
positive regulation of nucleotide metabolic processGO:00459812300.017
activation of protein kinase activityGO:0032147900.017
chromatin modificationGO:00165682980.017
microtubule cytoskeleton organizationGO:00002261760.017
peptidyl lysine acetylationGO:00183941010.017
internal protein amino acid acetylationGO:00064751010.017
transcription elongation from rna polymerase ii promoterGO:0006368180.017
diterpenoid metabolic processGO:0016101200.017
negative regulation of camp mediated signalingGO:004395140.017
regulation of leukocyte differentiationGO:1902105610.017
regulation of protein localization to nucleusGO:1900180850.017
response to hypoxiaGO:0001666960.017
negative regulation of innate immune responseGO:0045824180.017
response to activityGO:001482300.017
modification dependent protein catabolic processGO:00199412090.017
tissue regenerationGO:004224630.017
cellular component disassemblyGO:0022411920.016
regulation of mapk cascadeGO:00434082620.016
positive regulation of mapk cascadeGO:00434101900.016
symbiosis encompassing mutualism through parasitismGO:00444031560.016
purine nucleoside monophosphate metabolic processGO:00091261860.016
cellular homeostasisGO:00197251960.016
modification dependent macromolecule catabolic processGO:00436322120.016
protein acylationGO:00435431380.016
protein targetingGO:00066051870.016
regulation of stress activated mapk cascadeGO:0032872840.015
negative regulation of synaptic transmissionGO:005080520.015
negative regulation of organelle organizationGO:00106391260.015
negative regulation of smooth muscle cell proliferationGO:0048662140.015
stress activated mapk cascadeGO:0051403930.015
respiratory system processGO:000301630.015
positive regulation of cellular catabolic processGO:00313312840.015
cellular macromolecular complex assemblyGO:00346223240.015
regulation of lipid metabolic processGO:0019216960.015
cellular protein catabolic processGO:00442572610.015
single organismal cell cell adhesionGO:00163371480.015
protein stabilizationGO:0050821640.015
regulation of cellular protein catabolic processGO:1903362960.015
regulation of cellular response to growth factor stimulusGO:0090287760.014
nucleoside triphosphate metabolic processGO:00091414220.014
regulation of cytoplasmic transportGO:19036491490.014
rna processingGO:00063962550.014
tripartite regional subdivisionGO:000735120.014
blood vessel morphogenesisGO:00485141620.014
macromolecule methylationGO:0043414970.014
stress activated protein kinase signaling cascadeGO:0031098940.014
cellular response to hydrogen peroxideGO:0070301370.014
regulation of proteolysisGO:00301622930.014
nuclear transportGO:00511691790.014
protein processingGO:00164852260.014
metal ion homeostasisGO:00550651690.014
negative regulation of cellular amino acid metabolic processGO:004576320.014
meiosis iGO:000712740.014
regulation of protein stabilityGO:0031647870.014
epithelium migrationGO:00901321190.014
mitotic cell cycleGO:00002783260.014
regulation of leukocyte proliferationGO:0070663670.014
regulation of response to cytokine stimulusGO:0060759460.013
response to virusGO:00096151260.013
single organism reproductive processGO:0044702980.013
cell projection assemblyGO:00300311260.013
organelle fusionGO:0048284360.013
response to transition metal nanoparticleGO:1990267290.013
negative regulation of transcription from rna polymerase ii promoterGO:00001222810.013
positive regulation of transportGO:00510503360.013
lipid metabolic processGO:00066293810.013
chromatin assemblyGO:0031497610.013
leukocyte differentiationGO:0002521980.013
response to uvGO:0009411730.013
innate immune response activating signal transductionGO:0002758480.013
ribonucleoside triphosphate catabolic processGO:00092033910.013
positive regulation of cytosolic calcium ion concentrationGO:0007204820.013
negative regulation of response to external stimulusGO:0032102830.013
intracellular protein transportGO:00068862700.013
negative regulation of phosphate metabolic processGO:00459362670.013
positive regulation of mitochondrion organizationGO:0010822300.013
protein complex disassemblyGO:0043241520.013
response to woundingGO:00096111680.013
ribonucleoprotein complex localizationGO:007116640.013
negative regulation of sequence specific dna binding transcription factor activityGO:0043433890.013
mitochondrion organizationGO:00070051560.013
protein k63 linked deubiquitinationGO:0070536210.013
regulation of dna templated transcription elongationGO:0032784230.013
embryo developmentGO:00097901230.013
Worm
protein maturationGO:00516042330.013
negative regulation of extrinsic apoptotic signaling pathway via death domain receptorsGO:1902042150.013
vasodilationGO:004231140.013
cellular response to inorganic substanceGO:0071241450.013
regulation of epithelial cell migrationGO:0010632930.013
regulation of oxidative stress induced cell deathGO:1903201240.013
cellular response to organic cyclic compoundGO:00714071270.013
single organism membrane organizationGO:00448022680.013
proteasome mediated ubiquitin dependent protein catabolic processGO:00431611560.013
protein k48 linked deubiquitinationGO:0071108190.013
male meiosisGO:000714010.013
ion transmembrane transportGO:00342203380.013
calcium ion transportGO:00068161470.013
snrna transcription from rna polymerase ii promoterGO:004279570.013
ncrna metabolic processGO:00346601080.012
microtubule based processGO:00070172100.012
regulation of cellular amino acid metabolic processGO:000652160.012
anterior posterior axis specificationGO:000994820.012
positive regulation of reactive oxygen species biosynthetic processGO:190342820.012
regulation of homeostatic processGO:00328441210.012
forebrain generation of neuronsGO:002187230.012
regulation of cytoskeleton organizationGO:00514931770.012
regulation of endosome sizeGO:005103630.012
regulation of cell cell adhesionGO:0022407570.012
regulation of nitric oxide biosynthetic processGO:0045428170.012
positive regulation of toll like receptor signaling pathwayGO:0034123100.012
cell death in response to oxidative stressGO:0036473290.012
cellular response to dna damage stimulusGO:00069743790.012
hemopoiesisGO:00300971800.012
organophosphate biosynthetic processGO:00904071630.012
response to metal ionGO:0010038840.012
regulation of metal ion transportGO:00109591200.012
ribonucleoside monophosphate metabolic processGO:00091611870.012
ribonucleoside triphosphate metabolic processGO:00091994120.012
purine nucleoside triphosphate catabolic processGO:00091463920.012
regulation of dna metabolic processGO:00510521530.012
positive regulation of proteolysisGO:00458621420.011
cell cycle checkpointGO:00000751170.011
posttranscriptional regulation of gene expressionGO:00106082130.011
protein refoldingGO:0042026140.011
regulation of secretionGO:00510461940.011
regulation of cellular component movementGO:00512703340.011
receptor metabolic processGO:0043112810.011
organonitrogen compound biosynthetic processGO:19015662000.011
establishment of protein localization to organelleGO:00725941720.011
hemoglobin metabolic processGO:002002730.011
regulation of vasculature developmentGO:1901342970.011
regulation of camp metabolic processGO:0030814520.011
negative regulation of protein maturationGO:19033181420.011
tissue migrationGO:00901301190.011
regulation of vesicle mediated transportGO:00606271300.011
rrna metabolic processGO:0016072400.011
regulation of intrinsic apoptotic signaling pathwayGO:2001242720.011
cation transmembrane transportGO:00986552380.011
membrane protein proteolysisGO:0033619380.011
agingGO:0007568660.011
Worm
regulation of gtp catabolic processGO:00331241800.011
positive regulation of interferon beta biosynthetic processGO:004535940.011
cell growthGO:00160491600.011
enzyme linked receptor protein signaling pathwayGO:00071673030.011
positive regulation of transferase activityGO:00513472270.011
cation homeostasisGO:00550801890.011
positive regulation of protein phosphorylationGO:00019343130.011
cofactor biosynthetic processGO:0051188310.011
purine nucleoside triphosphate metabolic processGO:00091444120.011
gtp catabolic processGO:00061842370.011
regulation of response to biotic stimulusGO:0002831550.011
response to calcium ionGO:0051592460.011
negative regulation of systemic arterial blood pressureGO:000308510.011
positive regulation of secretionGO:00510471160.011
interleukin 8 productionGO:0032637510.011
rna interferenceGO:001624640.011
negative regulation of kinase activityGO:00336731060.011
divalent inorganic cation homeostasisGO:00725071360.010
negative regulation of cell activationGO:0050866330.010
protein catabolic processGO:00301633250.010
regulation of chemokine productionGO:0032642310.010
regulation of dendritic cell differentiationGO:200119830.010
regulation of t cell activationGO:0050863770.010
ectodermal placode formationGO:006078810.010
regulation of ion transmembrane transporter activityGO:0032412720.010
negative regulation of phosphorylationGO:00423261740.010
nucleosome assemblyGO:0006334500.010
hemostasisGO:0007599760.010
response to light stimulusGO:0009416870.010
epithelial cell developmentGO:0002064340.010
positive regulation of endocytosisGO:0045807420.010
negative regulation of intrinsic apoptotic signaling pathwayGO:2001243400.010
peripheral nervous system developmentGO:000742220.010
response to endoplasmic reticulum stressGO:0034976490.010
wnt signaling pathwayGO:00160551560.010

FTH1 disease predictions

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of metabolismDOID:00146672950.078
lysosomal storage diseaseDOID:3211470.069
inherited metabolic disorderDOID:6552420.069
disease of cellular proliferationDOID:145661740.037
lipid storage diseaseDOID:9455280.034
connective tissue diseaseDOID:651090.025
musculoskeletal system diseaseDOID:172230.025
eye and adnexa diseaseDOID:14921500.022
nervous system diseaseDOID:8634310.022
eye diseaseDOID:56141490.022
sensory system diseaseDOID:00501552030.022