Homo sapiens

5 known processes

ATG16L1

ATG16 autophagy related 16-like 1 (S. cerevisiae)

(Aliases: FLJ00045,FLJ10828,FLJ22677,FLJ10035,IBD10,APG16L,ATG16L,WDR30,ATG16A)

ATG16L1 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
autophagic vacuole assemblyGO:0000045190.689
macroautophagyGO:0016236390.307
Worm
vacuole organizationGO:0007033440.267
organelle assemblyGO:00709251760.216
Worm
cytoplasmic transportGO:00164823790.191
cellular amino acid metabolic processGO:00065201160.184
autophagyGO:0006914880.180
Worm Fly
regulation of autophagyGO:0010506520.168
Fly
post embryonic developmentGO:000979120.159
Fly
regulation of neurotrophin trk receptor signaling pathwayGO:005138620.148
determination of adult lifespanGO:000834020.145
vasodilationGO:004231140.132
regulation of protein localizationGO:00328802960.130
negative regulation of apoptotic processGO:00430663160.117
chromatin modificationGO:00165682980.116
negative regulation of cellular amine metabolic processGO:003323930.113
negative regulation of programmed cell deathGO:00430693210.112
negative regulation of axonogenesisGO:005077140.110
cellular ketone metabolic processGO:0042180800.110
regulation of cellular amino acid metabolic processGO:000652160.110
cellular protein complex assemblyGO:00436231880.107
Worm
cellular response to external stimulusGO:00714961110.106
Worm
multicellular organismal agingGO:001025930.105
positive regulation of autophagyGO:0010508240.104
cellular response to nutrient levelsGO:0031669690.100
Worm
membrane organizationGO:00610242920.100
regenerationGO:003109940.089
regulation of establishment of protein localizationGO:00702012420.088
negative regulation of cell deathGO:00605483450.086
cell morphogenesisGO:00009022960.085
single organism cellular localizationGO:19025803320.085
single organism membrane organizationGO:00448022680.084
metal ion transportGO:00300012720.084
cellular response to starvationGO:0009267580.083
Worm
interspecies interaction between organismsGO:00444191560.083
Mouse
actin filament based processGO:00300292240.082
Worm
amine metabolic processGO:0009308440.082
cellular macromolecular complex assemblyGO:00346223240.078
Worm
positive regulation of transportGO:00510503360.078
regulation of anatomical structure morphogenesisGO:00226032860.077
apoptotic signaling pathwayGO:00971902680.076
negative regulation of cellular amino acid metabolic processGO:004576320.073
cellular amine metabolic processGO:0044106410.073
regulation of cytokine productionGO:00018172320.072
negative regulation of protein modification processGO:00314002000.072
growthGO:00400072020.070
Worm
defense responseGO:00069523150.070
Worm
c terminal protein amino acid modificationGO:001841010.068
regulation of cellular amine metabolic processGO:0033238110.068
cellular homeostasisGO:00197251960.068
negative regulation of cellular component organizationGO:00511292350.066
response to nutrient levelsGO:0031667810.065
Worm
regulation of anatomical structure sizeGO:00900661010.065
cilium morphogenesisGO:0060271750.063
protein targetingGO:00066051870.063
histone acetylationGO:0016573930.062
myosin filament assemblyGO:003103420.062
Worm
negative regulation of protein metabolic processGO:00512483910.061
cilium assemblyGO:0042384630.061
negative regulation of cellular protein metabolic processGO:00322693530.061
multi organism cellular processGO:00447641560.059
Mouse
protein lipidationGO:0006497330.057
protein localization to organelleGO:00333652800.057
carbohydrate metabolic processGO:00059752070.056
intracellular protein transportGO:00068862700.056
collateral sproutingGO:004866820.055
immune responseGO:00069553070.055
protein autophosphorylationGO:00467771230.055
actin cytoskeleton organizationGO:00300362070.054
Worm
cellular component assembly involved in morphogenesisGO:0010927730.052
Worm
mapk cascadeGO:00001652880.052
cell projection organizationGO:00300302520.052
lipoprotein biosynthetic processGO:0042158330.051
protein catabolic processGO:00301633250.051
regulation of apoptotic signaling pathwayGO:20012331750.050
ion homeostasisGO:00508012300.050
cellular response to extracellular stimulusGO:0031668720.049
Worm
glycosyl compound catabolic processGO:19016584130.048
carbohydrate derivative biosynthetic processGO:19011372070.048
metencephalon developmentGO:002203720.047
lipoprotein metabolic processGO:0042157420.047
viral processGO:00160321460.047
Mouse
regulation of ion transportGO:00432691890.046
response to other organismGO:00517072610.046
Worm
positive regulation of protein phosphorylationGO:00019343130.046
necrotic cell deathGO:0070265210.046
anatomical structure formation involved in morphogenesisGO:00486462840.045
Worm
oogenesisGO:004847720.045
regulation of extrinsic apoptotic signaling pathwayGO:2001236850.045
response to starvationGO:0042594590.045
Worm
striated muscle myosin thick filament assemblyGO:007168820.044
Worm
lipid metabolic processGO:00066293810.044
positive regulation of cell sizeGO:004579330.044
cellular ion homeostasisGO:00068731680.043
histone modificationGO:00165702510.043
hindbrain developmentGO:003090230.043
positive regulation of cellular amino acid metabolic processGO:004576430.042
peptidyl lysine acetylationGO:00183941010.042
response to fungusGO:000962040.041
glycoprotein metabolic processGO:00091001100.040
innate immune responseGO:00450871780.040
taxisGO:00423301570.040
establishment of protein localization to organelleGO:00725941720.039
myosin filament organizationGO:003103320.039
Worm
metal ion homeostasisGO:00550651690.039
stress activated protein kinase signaling cascadeGO:0031098940.039
regulation of cellular component biogenesisGO:00440872810.038
cell developmentGO:00484683280.038
Worm Fly
regulation of secretion by cellGO:19035301770.038
maintenance of locationGO:00512351120.038
regulation of cellular ketone metabolic processGO:0010565500.038
extrinsic apoptotic signaling pathwayGO:00971911190.038
calcium ion homeostasisGO:00550741220.038
positive regulation of programmed cell deathGO:00430682490.037
internal peptidyl lysine acetylationGO:0018393970.037
nucleotide catabolic processGO:00091664080.037
ventricular cardiac muscle cell differentiationGO:005501210.036
cellular component morphogenesisGO:00329893140.036
Worm
regulation of homeostatic processGO:00328441210.036
response to extracellular stimulusGO:0009991850.036
Worm
cytokine secretionGO:0050663640.035
positive regulation of catabolic processGO:00098963100.035
regulation of secretionGO:00510461940.035
nervous system developmentGO:00073992930.035
ribonucleoside catabolic processGO:00424544060.035
regulation of metal ion transportGO:00109591200.035
sequestering of metal ionGO:0051238240.035
positive regulation of cell deathGO:00109422630.034
viral life cycleGO:00190581320.034
Mouse
regulation of cell morphogenesisGO:00226041530.034
cellular macromolecule catabolic processGO:00442653800.034
protein targeting to vacuoleGO:000662380.034
ribonucleoside triphosphate metabolic processGO:00091994120.034
locomotory behaviorGO:000762610.033
divalent inorganic cation homeostasisGO:00725071360.033
regulation of immune effector processGO:0002697910.033
cardiovascular system developmentGO:00723582620.033
regulation of response to external stimulusGO:00321012220.033
nucleoside triphosphate catabolic processGO:00091433940.033
internal protein amino acid acetylationGO:00064751010.032
positive regulation of cellular amine metabolic processGO:003324070.032
regulation of sequence specific dna binding transcription factor activityGO:00510902110.032
regulation of cytoplasmic transportGO:19036491490.032
regulation of cellular component sizeGO:0032535820.031
regulation of protein secretionGO:0050708860.031
chemical homeostasisGO:00488783060.031
reactive oxygen species metabolic processGO:0072593750.031
cellular chemical homeostasisGO:00550821800.031
protein acetylationGO:00064731160.030
positive regulation of apoptotic processGO:00430652460.030
regulation of cytokine secretionGO:0050707570.029
cellular lipid metabolic processGO:00442553030.029
regulation of body fluid levelsGO:0050878990.029
response to oxygen containing compoundGO:19017003690.029
cerebellum developmentGO:002154920.029
system processGO:00030083490.028
cellular divalent inorganic cation homeostasisGO:00725031280.028
divalent inorganic cation transportGO:00725111580.028
cytokine productionGO:00018162470.028
regulation of immune responseGO:00507762010.028
purine ribonucleoside metabolic processGO:00461284370.028
chromatin organizationGO:00063253510.028
cell part morphogenesisGO:00329901370.028
positive regulation of immune system processGO:00026842830.028
regulation of cell differentiationGO:00455953930.027
negative regulation of organelle organizationGO:00106391260.027
nucleoside triphosphate metabolic processGO:00091414220.027
nucleoside phosphate catabolic processGO:19012924120.027
organophosphate catabolic processGO:00464344300.027
negative regulation of cell growthGO:0030308830.027
stress activated mapk cascadeGO:0051403930.027
purine nucleoside catabolic processGO:00061523980.026
purine nucleoside triphosphate catabolic processGO:00091463920.026
vesicle mediated transportGO:00161923710.026
purine ribonucleoside catabolic processGO:00461303980.026
symbiosis encompassing mutualism through parasitismGO:00444031560.025
Mouse
purine ribonucleotide catabolic processGO:00091544040.025
protein acylationGO:00435431380.025
cell projection assemblyGO:00300311260.025
protein processingGO:00164852260.025
blood vessel remodelingGO:000197420.025
regulation of cellular response to stressGO:00801352440.024
memoryGO:000761330.024
covalent chromatin modificationGO:00165692540.024
negative regulation of extrinsic apoptotic signaling pathwayGO:2001237520.024
microtubule cytoskeleton organizationGO:00002261760.024
small gtpase mediated signal transductionGO:0007264780.024
purine nucleotide catabolic processGO:00061954050.024
cellular calcium ion homeostasisGO:00068741170.024
nucleoside catabolic processGO:00091644080.023
histone h4 k16 acetylationGO:0043984140.023
positive regulation of hydrolase activityGO:00513453310.023
cytosolic calcium ion homeostasisGO:0051480890.023
protein glycosylationGO:0006486620.023
regulation of cellular response to growth factor stimulusGO:0090287760.023
cation transportGO:00068123310.023
cell projection morphogenesisGO:00488581290.022
positive regulation of immune responseGO:00507781590.022
negative regulation of growthGO:0045926970.022
ribonucleoside triphosphate catabolic processGO:00092033910.022
purine nucleoside triphosphate metabolic processGO:00091444120.022
positive regulation of secretionGO:00510471160.022
regulation of protein serine threonine kinase activityGO:00719001790.022
purine ribonucleoside triphosphate metabolic processGO:00092054110.022
segmentationGO:003528240.021
chemotaxisGO:00069351570.021
purine ribonucleoside triphosphate catabolic processGO:00092073910.021
female gamete generationGO:000729220.021
negative regulation of phosphate metabolic processGO:00459362670.021
regulation of protein modification by small protein conjugation or removalGO:19033201070.021
dephosphorylationGO:00163112090.021
rna processingGO:00063962550.021
immune effector processGO:00022521590.021
cellular protein catabolic processGO:00442572610.021
ribonucleoside monophosphate metabolic processGO:00091611870.021
regulation of chromosome organizationGO:00330441030.020
positive regulation of cellular catabolic processGO:00313312840.020
cellular carbohydrate metabolic processGO:0044262840.020
secretion by cellGO:00329402260.020
neuromuscular junction developmentGO:000752830.020
striated muscle cell differentiationGO:0051146430.020
Worm
i kappab kinase nf kappab signalingGO:00072491660.020
purine ribonucleoside monophosphate metabolic processGO:00091671860.020
oxidation reduction processGO:00551143960.020
protein maturationGO:00516042330.020
purine nucleoside monophosphate metabolic processGO:00091261860.020
regulation of transferase activityGO:00513383550.020
cell growthGO:00160491600.020
neurotrophin trk receptor signaling pathwayGO:004801140.020
ribonucleotide catabolic processGO:00092614050.020
sequestering of calcium ionGO:0051208170.020
regulation of intracellular transportGO:00323861950.020
cation homeostasisGO:00550801890.020
ion transmembrane transportGO:00342203380.020
negative regulation of chromosome organizationGO:2001251480.020
negative regulation of catalytic activityGO:00430863350.019
regulation of kinase activityGO:00435493140.019
cellular metal ion homeostasisGO:00068751460.019
regulation of protein kinase activityGO:00458592890.019
regulation of proteolysisGO:00301622930.019
regulation of protein transportGO:00512232130.019
positive regulation of apoptotic signaling pathwayGO:2001235700.019
positive regulation of i kappab kinase nf kappab signalingGO:00431231320.019
positive regulation of synaptic transmissionGO:005080640.019
ribonucleoside monophosphate catabolic processGO:00091581580.018
organonitrogen compound biosynthetic processGO:19015662000.018
nucleoside monophosphate catabolic processGO:00091251590.018
peptidyl lysine modificationGO:00182051440.018
nucleoside monophosphate metabolic processGO:00091231910.018
regulation of collateral sproutingGO:004867020.018
negative regulation of protein ubiquitinationGO:0031397350.018
regulation of cell projection organizationGO:00313441070.018
regulation of calcium ion transport into cytosolGO:0010522330.018
spermatid developmentGO:000728640.018
regulation of protein ubiquitinationGO:0031396950.018
nitrogen compound transportGO:00717051910.018
regulation of cilium assemblyGO:190201760.018
negative regulation of multicellular organismal processGO:00512413170.018
regulation of reactive oxygen species metabolic processGO:2000377410.018
ras protein signal transductionGO:0007265730.018
establishment of protein localization to membraneGO:00901501210.018
atp metabolic processGO:00460341760.018
transmembrane transportGO:00550853990.017
cellular response to dna damage stimulusGO:00069743790.017
endomembrane system organizationGO:00102561960.017
calcium ion transportGO:00068161470.017
neuron differentiationGO:00301821380.017
glycosylationGO:0070085710.017
endosomal transportGO:00161971290.017
negative regulation of developmental processGO:00510932470.017
muscle cell differentiationGO:0042692630.017
Worm
proteasomal protein catabolic processGO:00104981760.017
regulation of cell growthGO:00015581350.017
regulation of blood vessel sizeGO:0050880180.017
response to biotic stimulusGO:00096072760.017
Worm
modification dependent protein catabolic processGO:00199412090.017
negative regulation of intracellular signal transductionGO:19025321830.017
muscle structure developmentGO:0061061980.016
Worm
protein localization to membraneGO:00726571600.016
positive regulation of developmental processGO:00510943140.016
intrinsic apoptotic signaling pathwayGO:00971931270.016
positive regulation of phosphorylationGO:00423273940.016
adult locomotory behaviorGO:000834410.016
neurotransmitter secretionGO:000726940.016
rna interferenceGO:001624640.016
cellular cation homeostasisGO:00300031630.016
microtubule based processGO:00070172100.016
guanosine containing compound catabolic processGO:19010692390.016
regulation of ion homeostasisGO:2000021730.016
blastoderm segmentationGO:000735020.016
positive regulation of cellular component organizationGO:00511303760.016
mucus secretionGO:007025410.016
positive regulation of protein kinase activityGO:00458601900.016
cell morphogenesis involved in differentiationGO:00009041440.016
central nervous system developmentGO:00074171230.016
regulation of i kappab kinase nf kappab signalingGO:00431221620.016
long term memoryGO:000761620.016
modification dependent macromolecule catabolic processGO:00436322120.016
response to growth factorGO:00708482050.015
enzyme linked receptor protein signaling pathwayGO:00071673030.015
positive regulation of cytosolic calcium ion concentrationGO:0007204820.015
negative regulation of phosphorus metabolic processGO:00105632670.015
macromolecule glycosylationGO:0043413630.015
mitotic cell cycle processGO:19030472860.015
negative regulation of homeostatic processGO:0032845590.015
blood circulationGO:00080151130.015
compound eye developmentGO:004874910.015
regulation of cytoskeleton organizationGO:00514931770.015
purine ribonucleoside monophosphate catabolic processGO:00091691580.015
associative learningGO:000830610.015
cellular component disassemblyGO:0022411920.015
regulation of calcium ion transportGO:0051924790.015
protein localization to vacuoleGO:0072665110.015
response to cytokineGO:00340972320.015
spermatid differentiationGO:004851540.015
nucleocytoplasmic transportGO:00069131760.015
rna splicingGO:00083801310.014
nuclear importGO:00511701060.014
purine containing compound catabolic processGO:00725234110.014
receptor metabolic processGO:0043112810.014
circulatory system processGO:00030131130.014
ubiquitin dependent protein catabolic processGO:00065112060.014
proteasome mediated ubiquitin dependent protein catabolic processGO:00431611560.014
regulation of defense responseGO:00313471540.014
regulation of endopeptidase activityGO:00525481700.014
small molecule biosynthetic processGO:00442831570.014
peptidyl tyrosine modificationGO:00182121700.014
cilium organizationGO:0044782680.014
regulation of protein maturationGO:19033171500.014
positive regulation of transferase activityGO:00513472270.014
response to lipidGO:00339932060.014
single organism carbohydrate metabolic processGO:00447231930.014
divalent metal ion transportGO:00708381520.014
cell fate determinationGO:000170930.014
monovalent inorganic cation transportGO:00156721280.014
head developmentGO:00603221080.014
peripheral nervous system developmentGO:000742220.014
cerebellar cortex developmentGO:002169510.014
regulation of cellular protein catabolic processGO:1903362960.014
peptidyl tyrosine phosphorylationGO:00181081700.014
histone h4 acetylationGO:0043967470.014
signal transduction by phosphorylationGO:00230142970.014
release of cytoplasmic sequestered nf kappabGO:000858840.014
negative regulation of phosphorylationGO:00423261740.014
neurogenesisGO:00220081690.014
regulation of dephosphorylationGO:0035303960.014
anterior posterior axis specificationGO:000994820.014
positive regulation of nf kappab transcription factor activityGO:0051092810.014
regulation of nucleotide metabolic processGO:00061402690.014
regulation of peptidase activityGO:00525471800.014
gtp metabolic processGO:00460392390.014
reactive nitrogen species metabolic processGO:200105730.013
regulation of synaptic plasticityGO:004816730.013
brain developmentGO:0007420970.013
regulation of protein processingGO:00706131500.013
regulation of dna metabolic processGO:00510521530.013
generation of neuronsGO:00486991520.013
salivary gland morphogenesisGO:000743540.013
negative regulation of sequestering of calcium ionGO:0051283410.013
regulation of purine nucleotide catabolic processGO:00331212050.013
neurological system processGO:00508771630.013
regulation of sequestering of calcium ionGO:0051282410.013
negative regulation of protein processingGO:00109551420.013
regulation of growthGO:00400081650.013
positive regulation of mapk cascadeGO:00434101900.013
cellular response to growth factor stimulusGO:00713631970.013
glycerolipid metabolic processGO:00464861070.013
protein secretionGO:0009306980.013
organophosphate biosynthetic processGO:00904071630.013
positive regulation of purine nucleotide catabolic processGO:00331231850.013
hematopoietic or lymphoid organ developmentGO:00485341860.013
positive regulation of cell proliferationGO:00082843010.013
gtp catabolic processGO:00061842370.013
cellular response to cytokine stimulusGO:00713451810.013
response to drugGO:0042493810.013
glycoprotein biosynthetic processGO:0009101910.013
receptor internalizationGO:0031623430.013
t cell differentiation in thymusGO:003307740.013
biological adhesionGO:00226103310.013
negative regulation of cell differentiationGO:00455961710.013
circulatory system developmentGO:00723592620.013
calcium ion transport into cytosolGO:0060402480.013
tissue regenerationGO:004224630.013
positive regulation of cell differentiationGO:00455972110.013
regulation of cell cycle processGO:00105642660.013
oocyte developmentGO:004859910.013
matingGO:000761810.013
proteolysis involved in cellular protein catabolic processGO:00516032440.013
anatomical structure homeostasisGO:00602491000.012
protein kinase b signalingGO:0043491690.012
negative regulation of cell proliferationGO:00082852280.012
positive regulation of sequence specific dna binding transcription factor activityGO:00510911310.012
cytosolic calcium ion transportGO:0060401480.012
positive regulation of kinase activityGO:00336742040.012
regulation of cell developmentGO:00602841610.012
reactive oxygen species biosynthetic processGO:190340940.012
positive regulation of organelle organizationGO:00106381950.012
regulation of histone modificationGO:0031056470.012
motor neuron axon guidanceGO:000804520.012
alditol phosphate metabolic processGO:005264630.012
positive regulation of nucleotide metabolic processGO:00459812300.012
purine nucleoside monophosphate catabolic processGO:00091281580.012
regulation of reactive oxygen species biosynthetic processGO:190342630.012
negative regulation of transportGO:00510511760.012
negative regulation of cell developmentGO:0010721480.012
hemopoiesisGO:00300971800.012
protein modification by small protein conjugationGO:00324463420.012
negative regulation of protein maturationGO:19033181420.012
regulation of organelle assemblyGO:1902115400.012
mrna metabolic processGO:00160711750.012
syncytium formation by plasma membrane fusionGO:000076820.012
rho protein signal transductionGO:0007266260.012
regulation of cell divisionGO:00513021160.012
vacuolar transportGO:0007034340.012
rhythmic behaviorGO:000762220.012
response to organic cyclic compoundGO:00140702040.012
regulation of mitotic cell cycle phase transitionGO:19019901180.012
regulation of purine nucleotide metabolic processGO:19005422640.012
positive regulation of cysteine type endopeptidase activity involved in apoptotic processGO:0043280690.012
mrna processingGO:00063971330.011
mitochondrion organizationGO:00070051560.011
cardiac muscle cell contractionGO:008600340.011
wnt signaling pathwayGO:00160551560.011
production of molecular mediator of immune responseGO:0002440370.011
immune system developmentGO:00025201950.011
posttranscriptional regulation of gene expressionGO:00106082130.011
regulation of mapk cascadeGO:00434082620.011
neuron developmentGO:00486661130.011
negative regulation of protein phosphorylationGO:00019331400.011
oocyte differentiationGO:000999420.011
negative regulation of protein modification by small protein conjugation or removalGO:1903321410.011
regulation of neural precursor cell proliferationGO:200017740.011
response to external biotic stimulusGO:00432072610.011
Worm
regulation of lymphocyte activationGO:00512491030.011
response to woundingGO:00096111680.011
meiotic chromosome segregationGO:004513240.011
visual behaviorGO:000763220.011
regulation of cysteine type endopeptidase activity involved in apoptotic processGO:00432811160.011
protein deubiquitinationGO:0016579790.011
response to bacteriumGO:00096171440.011
Worm
regulation of vesicle mediated transportGO:00606271300.011
positive regulation of cysteine type endopeptidase activityGO:2001056790.011
positive regulation of peptidase activityGO:0010952880.011
regulation of cell migrationGO:00303342890.011
cytokine mediated signaling pathwayGO:00192211090.011
protein ubiquitinationGO:00165673140.011
vascular process in circulatory systemGO:0003018290.011
positive regulation of nucleoside metabolic processGO:00459791860.011
nucleic acid phosphodiester bond hydrolysisGO:00903051020.011
tripartite regional subdivisionGO:000735120.011
regulation of cytokine production involved in immune responseGO:0002718220.011
mitotic cell cycleGO:00002783260.011
anion transportGO:00068201610.011
regulation of cysteine type endopeptidase activityGO:20001161270.011
cell cycle phase transitionGO:00447701730.011
plasma membrane organizationGO:00070091150.011
heart contractionGO:0060047620.011
cellular response to lipidGO:00713961270.011
positive regulation of innate immune responseGO:0045089790.011
regulation of protein targetingGO:1903533910.011
secretionGO:00469032540.011
cation transmembrane transportGO:00986552380.010
positive regulation of protein transportGO:00512221350.010
cell type specific apoptotic processGO:00972851250.010
negative regulation of hydrolase activityGO:00513461820.010
cell adhesionGO:00071553250.010
astrocyte differentiationGO:004870840.010
atp catabolic processGO:00062001570.010
positive regulation of response to external stimulusGO:0032103880.010
primary neural tube formationGO:001402030.010
sex determinationGO:000753030.010
transmembrane receptor protein tyrosine kinase signaling pathwayGO:00071691810.010
negative regulation of catabolic processGO:00098951040.010

ATG16L1 disease predictions

DiseaseDO term IDSizeProbabilityFunc Analog Org
cancerDOID:1621670.063
disease of cellular proliferationDOID:145661740.063
organ system cancerDOID:00506861640.061
thoracic cancerDOID:5093210.038
breast cancerDOID:1612210.029
immune system diseaseDOID:29141550.020
disease of metabolismDOID:00146672950.019
central nervous system diseaseDOID:3311860.018
nervous system diseaseDOID:8634310.018
sensory system diseaseDOID:00501552030.017
hematopoietic system diseaseDOID:741000.014
musculoskeletal system diseaseDOID:172230.013
eye and adnexa diseaseDOID:14921500.013
eye diseaseDOID:56141490.013
inherited metabolic disorderDOID:6552420.011
retinal diseaseDOID:56791180.011
retinal degenerationDOID:8466890.011
connective tissue diseaseDOID:651090.010
bone diseaseDOID:0080001880.010
cardiovascular system diseaseDOID:12871060.010