Homo sapiens

36 known processes

DEFA1B

defensin, alpha 1B

(Aliases: HP-1,HNP-1,DEFA1,HP1)

DEFA1B biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
defense response to bacteriumGO:0042742630.125
defense responseGO:00069523150.124
cytokine productionGO:00018162470.116
innate immune responseGO:00450871780.106
response to bacteriumGO:00096171440.099
response to other organismGO:00517072610.096
regulation of cytokine productionGO:00018172320.094
defense response to other organismGO:00985421290.079
positive regulation of transportGO:00510503360.079
immune responseGO:00069553070.077
response to external biotic stimulusGO:00432072610.071
response to biotic stimulusGO:00096072760.067
positive regulation of immune system processGO:00026842830.066
cation transportGO:00068123310.055
response to oxygen containing compoundGO:19017003690.047
mucosal immune responseGO:0002385210.045
secretionGO:00469032540.043
regulation of response to external stimulusGO:00321012220.042
metal ion transportGO:00300012720.041
humoral immune responseGO:0006959490.041
post embryonic developmentGO:000979120.040
regulation of secretion by cellGO:19035301770.038
chemical homeostasisGO:00488783060.038
biological adhesionGO:00226103310.037
cation homeostasisGO:00550801890.037
negative regulation of multicellular organismal processGO:00512413170.037
positive regulation of immune responseGO:00507781590.037
response to abiotic stimulusGO:00096283360.036
secretion by cellGO:00329402260.035
amine metabolic processGO:0009308440.034
regulation of defense responseGO:00313471540.034
regulation of protein localizationGO:00328802960.034
cell adhesionGO:00071553250.034
vesicle mediated transportGO:00161923710.033
negative regulation of cell deathGO:00605483450.033
lipid metabolic processGO:00066293810.033
regulation of secretionGO:00510461940.032
ion homeostasisGO:00508012300.032
cytoplasmic transportGO:00164823790.032
regulation of cellular component movementGO:00512703340.032
regulation of protein transportGO:00512232130.031
system processGO:00030083490.031
determination of adult lifespanGO:000834020.030
positive regulation of cellular component organizationGO:00511303760.030
positive regulation of cell deathGO:00109422630.030
multicellular organismal agingGO:001025930.030
nitrogen compound transportGO:00717051910.029
hematopoietic or lymphoid organ developmentGO:00485341860.029
regulation of ion transportGO:00432691890.029
response to lipidGO:00339932060.028
apoptotic signaling pathwayGO:00971902680.028
regulation of establishment of protein localizationGO:00702012420.028
activation of immune responseGO:00022531140.028
metal ion homeostasisGO:00550651690.027
cellular metal ion homeostasisGO:00068751460.027
regulation of immune responseGO:00507762010.027
negative regulation of apoptotic processGO:00430663160.027
regulation of protein secretionGO:0050708860.027
myeloid cell differentiationGO:00300991170.026
negative regulation of protein metabolic processGO:00512483910.026
g protein coupled receptor signaling pathwayGO:00071862070.026
female gamete generationGO:000729220.026
negative regulation of cellular protein metabolic processGO:00322693530.026
positive regulation of developmental processGO:00510943140.025
cellular response to oxygen containing compoundGO:19017012760.025
single organism cell adhesionGO:00986021790.025
purine ribonucleoside catabolic processGO:00461303980.025
regulation of nucleotide metabolic processGO:00061402690.025
cellular amino acid metabolic processGO:00065201160.025
cell activationGO:00017752130.025
regulation of intracellular transportGO:00323861950.025
regulation of proteolysisGO:00301622930.024
regulation of cellular amine metabolic processGO:0033238110.024
cellular amine metabolic processGO:0044106410.024
positive regulation of nucleotide metabolic processGO:00459812300.024
positive regulation of catabolic processGO:00098963100.024
protein processingGO:00164852260.024
positive regulation of secretion by cellGO:19035321080.024
regulation of transferase activityGO:00513383550.023
response to cytokineGO:00340972320.023
purine ribonucleoside triphosphate metabolic processGO:00092054110.023
positive regulation of cell differentiationGO:00455972110.023
positive regulation of cytokine productionGO:00018191670.023
regulation of cell differentiationGO:00455953930.023
positive regulation of hydrolase activityGO:00513453310.023
negative regulation of catalytic activityGO:00430863350.023
positive regulation of apoptotic processGO:00430652460.023
hemopoiesisGO:00300971800.022
organophosphate catabolic processGO:00464344300.022
positive regulation of secretionGO:00510471160.022
regulation of cellular amino acid metabolic processGO:000652160.022
protein catabolic processGO:00301633250.022
cellular response to dna damage stimulusGO:00069743790.022
oogenesisGO:004847720.022
purine ribonucleoside metabolic processGO:00461284370.022
single organismal cell cell adhesionGO:00163371480.022
positive regulation of cell migrationGO:00303351720.022
cellular lipid metabolic processGO:00442553030.021
cellular macromolecule catabolic processGO:00442653800.021
neuromuscular junction developmentGO:000752830.021
positive regulation of cellular amine metabolic processGO:003324070.021
divalent metal ion transportGO:00708381520.021
cellular cation homeostasisGO:00300031630.021
leukocyte activationGO:00453211640.021
locomotory behaviorGO:000762610.021
regulation of innate immune responseGO:0045088970.021
protein maturationGO:00516042330.021
purine nucleoside triphosphate metabolic processGO:00091444120.021
positive regulation of cell proliferationGO:00082843010.021
defense response to gram positive bacteriumGO:0050830290.021
immune response activating signal transductionGO:0002757900.021
protein localization to organelleGO:00333652800.021
ribonucleotide catabolic processGO:00092614050.021
response to woundingGO:00096111680.021
ribonucleoside triphosphate metabolic processGO:00091994120.021
maintenance of locationGO:00512351120.021
regulation of mapk cascadeGO:00434082620.020
mapk cascadeGO:00001652880.020
immune system developmentGO:00025201950.020
regulation of anatomical structure morphogenesisGO:00226032860.020
positive regulation of phosphorylationGO:00423273940.020
cellular ion homeostasisGO:00068731680.020
nucleoside triphosphate metabolic processGO:00091414220.020
regulation of kinase activityGO:00435493140.020
memoryGO:000761330.020
small gtpase mediated signal transductionGO:0007264780.020
protein secretionGO:0009306980.020
regulation of multi organism processGO:00439001570.020
negative regulation of cell proliferationGO:00082852280.020
purine containing compound catabolic processGO:00725234110.020
reactive oxygen species metabolic processGO:0072593750.020
signal transduction by phosphorylationGO:00230142970.019
immune response regulating signaling pathwayGO:0002764970.019
negative regulation of cytokine productionGO:0001818820.019
negative regulation of programmed cell deathGO:00430693210.019
positive regulation of cellular amino acid metabolic processGO:004576430.019
regulation of purine nucleotide metabolic processGO:19005422640.019
ribonucleoside triphosphate catabolic processGO:00092033910.019
regulation of cell cycleGO:00517263930.019
nucleotide catabolic processGO:00091664080.019
chemotaxisGO:00069351570.019
regulation of cell motilityGO:20001452990.019
nucleoside triphosphate catabolic processGO:00091433940.019
positive regulation of protein transportGO:00512221350.019
positive regulation of ion transportGO:0043270870.019
nucleoside phosphate catabolic processGO:19012924120.019
response to nitrogen compoundGO:19016981840.019
negative regulation of developmental processGO:00510932470.019
protein oligomerizationGO:00512591730.019
cellular response to cytokine stimulusGO:00713451810.019
regulation of protein kinase activityGO:00458592890.019
blood circulationGO:00080151130.018
positive regulation of innate immune responseGO:0045089790.018
regenerationGO:003109940.018
regulation of vesicle mediated transportGO:00606271300.018
transmembrane transportGO:00550853990.018
ribonucleoside catabolic processGO:00424544060.018
glycosyl compound catabolic processGO:19016584130.018
single organism membrane organizationGO:00448022680.018
positive regulation of cell motilityGO:20001471770.018
neurological system processGO:00508771630.018
angiogenesisGO:00015251470.018
nucleoside catabolic processGO:00091644080.018
purine ribonucleoside triphosphate catabolic processGO:00092073910.018
divalent inorganic cation transportGO:00725111580.018
purine nucleoside catabolic processGO:00061523980.018
oxidation reduction processGO:00551143960.018
actin filament based processGO:00300292240.018
cellular divalent inorganic cation homeostasisGO:00725031280.017
response to fungusGO:000962040.017
cell projection organizationGO:00300302520.017
negative regulation of phosphate metabolic processGO:00459362670.017
circulatory system developmentGO:00723592620.017
covalent chromatin modificationGO:00165692540.017
organonitrogen compound biosynthetic processGO:19015662000.017
regulation of cell activationGO:00508651250.017
ras protein signal transductionGO:0007265730.017
symbiosis encompassing mutualism through parasitismGO:00444031560.017
innate immune response activating signal transductionGO:0002758480.017
cellular protein catabolic processGO:00442572610.017
regulation of endopeptidase activityGO:00525481700.017
positive regulation of organelle organizationGO:00106381950.017
response to inorganic substanceGO:00100351270.017
negative regulation of phosphorus metabolic processGO:00105632670.017
positive regulation of programmed cell deathGO:00430682490.017
activation of innate immune responseGO:0002218550.017
lipid biosynthetic processGO:00086101770.017
positive regulation of cytosolic calcium ion concentrationGO:0007204820.017
response to lipopolysaccharideGO:0032496700.017
regulation of peptidase activityGO:00525471800.017
single organism cellular localizationGO:19025803320.017
positive regulation of locomotionGO:00400171860.016
regulation of i kappab kinase nf kappab signalingGO:00431221620.016
negative regulation of cellular component organizationGO:00511292350.016
antimicrobial humoral responseGO:0019730260.016
defense response to fungusGO:005083240.016
cellular macromolecular complex assemblyGO:00346223240.016
cellular chemical homeostasisGO:00550821800.016
purine nucleotide catabolic processGO:00061954050.016
cellular response to lipidGO:00713961270.016
anatomical structure formation involved in morphogenesisGO:00486462840.016
cellular homeostasisGO:00197251960.016
positive regulation of transferase activityGO:00513472270.016
response to axon injuryGO:004867810.016
cytokine secretionGO:0050663640.016
negative regulation of hydrolase activityGO:00513461820.016
membrane organizationGO:00610242920.016
positive regulation of defense responseGO:0031349870.016
regulation of cell migrationGO:00303342890.016
response to molecule of bacterial originGO:0002237820.016
regulation of cellular ketone metabolic processGO:0010565500.016
cell morphogenesisGO:00009022960.016
regulation of immune effector processGO:0002697910.016
i kappab kinase nf kappab signalingGO:00072491660.016
purine ribonucleotide catabolic processGO:00091544040.016
pattern recognition receptor signaling pathwayGO:0002221480.016
mitotic cell cycleGO:00002783260.016
regulation of apoptotic signaling pathwayGO:20012331750.016
positive regulation of purine nucleotide metabolic processGO:19005442270.015
purine nucleoside triphosphate catabolic processGO:00091463920.015
regulation of cellular response to stressGO:00801352440.015
ion transmembrane transportGO:00342203380.015
regulation of cytokine secretionGO:0050707570.015
vasculature developmentGO:00019441810.015
response to organic cyclic compoundGO:00140702040.015
regulation of cellular component biogenesisGO:00440872810.015
regulation of response to woundingGO:19030341010.015
cell developmentGO:00484683280.015
leukocyte migrationGO:00509001070.015
positive regulation of mapk cascadeGO:00434101900.015
cardiovascular system developmentGO:00723582620.015
leukocyte differentiationGO:0002521980.015
regulation of cell adhesionGO:00301551660.015
spermatid differentiationGO:004851540.015
chromatin organizationGO:00063253510.015
cellular ketone metabolic processGO:0042180800.015
positive regulation of cellular catabolic processGO:00313312840.015
cellular calcium ion homeostasisGO:00068741170.015
reactive oxygen species biosynthetic processGO:190340940.015
sequestering of metal ionGO:0051238240.015
nervous system developmentGO:00073992930.015
mitotic cell cycle processGO:19030472860.015
positive regulation of intracellular transportGO:00323881040.015
organ or tissue specific immune responseGO:0002251220.014
matingGO:000761810.014
response to radiationGO:00093141510.014
endocytosisGO:00068971590.014
regulation of cytoplasmic transportGO:19036491490.014
oocyte developmentGO:004859910.014
associative learningGO:000830610.014
divalent inorganic cation homeostasisGO:00725071360.014
negative regulation of intracellular signal transductionGO:19025321830.014
regulation of sequence specific dna binding transcription factor activityGO:00510902110.014
proteolysis involved in cellular protein catabolic processGO:00516032440.014
regulation of reactive oxygen species metabolic processGO:2000377410.014
oocyte differentiationGO:000999420.014
rho protein signal transductionGO:0007266260.014
muscle contractionGO:0006936730.014
posttranscriptional regulation of gene expressionGO:00106082130.014
segmentationGO:003528240.014
cytosolic calcium ion homeostasisGO:0051480890.014
intrinsic apoptotic signaling pathwayGO:00971931270.014
regulation of regulatory t cell differentiationGO:004558940.014
interspecies interaction between organismsGO:00444191560.013
positive regulation of kinase activityGO:00336742040.013
carbohydrate derivative biosynthetic processGO:19011372070.013
negative regulation of phosphorylationGO:00423261740.013
adult locomotory behaviorGO:000834410.013
intracellular estrogen receptor signaling pathwayGO:0030520230.013
regulation of myeloid cell differentiationGO:0045637810.013
calcium ion transportGO:00068161470.013
blood vessel morphogenesisGO:00485141620.013
chromatin modificationGO:00165682980.013
taxisGO:00423301570.013
histone modificationGO:00165702510.013
immune effector processGO:00022521590.013
cellular response to lipopolysaccharideGO:0071222570.013
negative regulation of cellular amino acid metabolic processGO:004576320.013
regulation of cysteine type endopeptidase activityGO:20001161270.013
regulation of interleukin 8 productionGO:0032677490.013
regulation of leukocyte migrationGO:0002685630.013
negative regulation of cellular amine metabolic processGO:003323930.013
regulation of protein processingGO:00706131500.013
positive regulation of cellular component biogenesisGO:00440891580.013
interleukin 8 productionGO:0032637510.013
regulation of cell morphogenesisGO:00226041530.013
atp metabolic processGO:00460341760.013
peripheral nervous system developmentGO:000742220.013
regulation of behaviorGO:0050795820.013
negative regulation of protein processingGO:00109551420.013
positive regulation of cellular component movementGO:00512721810.013
organic anion transportGO:00157111030.013
actin cytoskeleton organizationGO:00300362070.013
sequestering of calcium ionGO:0051208170.013
positive regulation of reactive oxygen species metabolic processGO:2000379240.013
epithelium migrationGO:00901321190.012
regulation of cell cycle processGO:00105642660.012
neuroblast proliferationGO:000740540.012
regulation of protein maturationGO:19033171500.012
response to oxygen levelsGO:00704821000.012
regulation of protein catabolic processGO:00421761550.012
protein ubiquitinationGO:00165673140.012
protein modification by small protein conjugationGO:00324463420.012
establishment of protein localization to organelleGO:00725941720.012
regulation of locomotionGO:00400123290.012
negative regulation of transportGO:00510511760.012
single organism carbohydrate metabolic processGO:00447231930.012
regulation of reactive oxygen species biosynthetic processGO:190342630.012
negative regulation of cell cycleGO:00457861930.012
positive regulation of nucleoside metabolic processGO:00459791860.012
reactive nitrogen species metabolic processGO:200105730.012
wound healingGO:00420601150.012
positive regulation of synaptic transmissionGO:005080640.012
calcium ion homeostasisGO:00550741220.012
purine nucleoside monophosphate metabolic processGO:00091261860.012
negative regulation of protein modification processGO:00314002000.012
enzyme linked receptor protein signaling pathwayGO:00071673030.012
antibacterial humoral responseGO:0019731240.012
rhythmic behaviorGO:000762220.012
positive regulation of i kappab kinase nf kappab signalingGO:00431231320.012
microtubule based processGO:00070172100.012
cell type specific apoptotic processGO:00972851250.012
negative regulation of transcription from rna polymerase ii promoterGO:00001222810.012
cellular response to molecule of bacterial originGO:0071219620.012
cell divisionGO:00513011680.012
cardiac muscle cell contractionGO:008600340.012
sensory perception of smellGO:000760820.012
sensory perception of painGO:001923340.012
multi organism cellular processGO:00447641560.012
negative regulation of immune system processGO:00026831360.012
modification dependent protein catabolic processGO:00199412090.012
positive regulation of proteolysisGO:00458621420.012
regulation of symbiosis encompassing mutualism through parasitismGO:00439031090.012
carbohydrate metabolic processGO:00059752070.012
ubiquitin dependent protein catabolic processGO:00065112060.012
blastoderm segmentationGO:000735020.012
cation transmembrane transportGO:00986552380.012
serotonin transportGO:000683730.012
positive regulation of leukocyte activationGO:0002696800.012
sensory perceptionGO:00076001030.012
inorganic ion transmembrane transportGO:00986602310.011
leukocyte chemotaxisGO:0030595760.011
regulation of chemotaxisGO:0050920740.011
spermatid developmentGO:000728640.011
regulation of neural precursor cell proliferationGO:200017740.011
regulation of angiogenesisGO:0045765920.011
positive regulation of protein kinase activityGO:00458601900.011
protein targetingGO:00066051870.011
proteasomal protein catabolic processGO:00104981760.011
cell killingGO:0001906340.011
organophosphate biosynthetic processGO:00904071630.011
regulation of tumor necrosis factor superfamily cytokine productionGO:1903555440.011
actin mediated cell contractionGO:0070252120.011
myeloid leukocyte differentiationGO:0002573600.011
regulation of homeostatic processGO:00328441210.011
blood coagulationGO:0007596760.011
phospholipid metabolic processGO:0006644990.011
syncytium formation by plasma membrane fusionGO:000076820.011
negative regulation of blood pressureGO:004577630.011
nucleoside monophosphate metabolic processGO:00091231910.011
regulation of protein complex assemblyGO:00432541470.011
cellular protein complex assemblyGO:00436231880.011
dephosphorylationGO:00163112090.011
coagulationGO:0050817780.011
cell chemotaxisGO:00603261120.011
positive regulation of interleukin 8 productionGO:0032757360.011
circadian behaviorGO:004851220.011
actin filament organizationGO:00070151280.011
negative regulation of homeostatic processGO:0032845590.011
regulation of leukocyte activationGO:00026941150.011
positive regulation of cytoplasmic transportGO:1903651820.011
immune response regulating cell surface receptor signaling pathwayGO:0002768510.011
platelet activationGO:0030168440.011
modification dependent macromolecule catabolic processGO:00436322120.011
photoreceptor cell differentiationGO:004653020.011
regulation of purine nucleotide catabolic processGO:00331212050.011
positive regulation of nucleotide catabolic processGO:00308131850.011
intracellular protein transportGO:00068862700.011
detection of stimulusGO:0051606850.011
striated muscle contractionGO:0006941520.011
disruption by host of symbiont cellsGO:005185220.011
growthGO:00400072020.011
positive regulation of cell activationGO:0050867810.011
negative regulation of proteolysisGO:00458611320.011
response to decreased oxygen levelsGO:0036293960.011
endomembrane system organizationGO:00102561960.011
organic hydroxy compound metabolic processGO:19016151470.011
negative regulation of cell differentiationGO:00455961710.011
rna processingGO:00063962550.011
regulation of membrane potentialGO:0042391950.011
regulation of cytoskeleton organizationGO:00514931770.011
regulation of body fluid levelsGO:0050878990.011
anion transportGO:00068201610.011
purine ribonucleoside monophosphate metabolic processGO:00091671860.011
regulation of cysteine type endopeptidase activity involved in apoptotic processGO:00432811160.011
regulation of endocytosisGO:0030100720.011
cell growthGO:00160491600.011
behaviorGO:00076101120.011
ribonucleoside monophosphate metabolic processGO:00091611870.011
mature dendritic cell differentiationGO:009702920.010
positive regulation of purine nucleotide catabolic processGO:00331231850.010
response to light stimulusGO:0009416870.010
regulation of tumor necrosis factor productionGO:0032680430.010
circulatory system processGO:00030131130.010
negative regulation of interferon beta productionGO:003268840.010
positive regulation of cell adhesionGO:0045785840.010
tissue migrationGO:00901301190.010
nuclear transportGO:00511691790.010
cellular component morphogenesisGO:00329893140.010
cardiac muscle contractionGO:0060048340.010
stem cell divisionGO:001714520.010
response to organonitrogen compoundGO:00102431560.010
response to metal ionGO:0010038840.010
negative regulation of catabolic processGO:00098951040.010
proteasome mediated ubiquitin dependent protein catabolic processGO:00431611560.010
compound eye developmentGO:004874910.010
tripartite regional subdivisionGO:000735120.010
alcohol metabolic processGO:00060661140.010
regulation of vasculature developmentGO:1901342970.010
microtubule cytoskeleton organizationGO:00002261760.010
positive regulation of response to external stimulusGO:0032103880.010
cellular response to oxidative stressGO:0034599850.010
cytokine mediated signaling pathwayGO:00192211090.010
regulation of synaptic plasticityGO:004816730.010
positive regulation of t cell activationGO:0050870540.010
cellular response to external stimulusGO:00714961110.010
axon regenerationGO:003110310.010
positive regulation of protein secretionGO:0050714600.010
erk1 and erk2 cascadeGO:00703711040.010

DEFA1B disease predictions

DiseaseDO term IDSizeProbabilityFunc Analog Org
immune system diseaseDOID:29141550.027
disease of metabolismDOID:00146672950.021
musculoskeletal system diseaseDOID:172230.017
inherited metabolic disorderDOID:6552420.017
sensory system diseaseDOID:00501552030.017
nervous system diseaseDOID:8634310.017
disease of cellular proliferationDOID:145661740.016
central nervous system diseaseDOID:3311860.015
hematopoietic system diseaseDOID:741000.014
cancerDOID:1621670.014
organ system cancerDOID:00506861640.014
eye and adnexa diseaseDOID:14921500.012
muscle tissue diseaseDOID:661130.012
muscular diseaseDOID:00800001140.012
eye diseaseDOID:56141490.012
disease by infectious agentDOID:0050117340.011
retinal diseaseDOID:56791180.011
neurodegenerative diseaseDOID:12891020.011
myopathyDOID:4231040.010
retinal degenerationDOID:8466890.010