Homo sapiens

91 known processes

MC2R

melanocortin 2 receptor (adrenocorticotropic hormone)

(Aliases: MGC125798,ACTHR)

MC2R biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
cyclic nucleotide metabolic processGO:0009187820.228
camp biosynthetic processGO:0006171470.220
transmembrane transportGO:00550853990.122
system processGO:00030083490.110
amine metabolic processGO:0009308440.108
g protein coupled receptor signaling pathwayGO:00071862070.104
Human Zebrafish
cyclic purine nucleotide metabolic processGO:0052652600.100
positive regulation of camp biosynthetic processGO:0030819350.100
cation transportGO:00068123310.098
regulation of camp biosynthetic processGO:0030817450.085
cellular ion homeostasisGO:00068731680.076
regulation of cyclic nucleotide metabolic processGO:0030799630.074
regulation of secretion by cellGO:19035301770.073
purine ribonucleotide biosynthetic processGO:0009152790.070
regulation of cellular amino acid metabolic processGO:000652160.068
divalent inorganic cation homeostasisGO:00725071360.066
cellular ketone metabolic processGO:0042180800.066
inorganic ion transmembrane transportGO:00986602310.065
positive regulation of camp metabolic processGO:0030816410.064
immune responseGO:00069553070.063
regulation of cytokine productionGO:00018172320.062
anion transportGO:00068201610.062
regulation of nucleotide metabolic processGO:00061402690.060
regulation of cellular amine metabolic processGO:0033238110.059
ribonucleotide biosynthetic processGO:0009260810.059
positive regulation of protein phosphorylationGO:00019343130.059
negative regulation of transportGO:00510511760.058
cellular metal ion homeostasisGO:00068751460.058
positive regulation of purine nucleotide metabolic processGO:19005442270.056
regulation of purine nucleotide metabolic processGO:19005422640.055
detection of chemical stimulus involved in sensory perceptionGO:0050907330.055
organonitrogen compound biosynthetic processGO:19015662000.054
cytosolic calcium ion homeostasisGO:0051480890.053
calcium ion homeostasisGO:00550741220.053
positive regulation of cell proliferationGO:00082843010.053
ion transmembrane transportGO:00342203380.052
ion homeostasisGO:00508012300.051
positive regulation of nucleotide metabolic processGO:00459812300.051
chemical homeostasisGO:00488783060.051
positive regulation of cyclic nucleotide biosynthetic processGO:0030804380.050
inorganic cation transmembrane transportGO:00986621940.050
regulation of ion transportGO:00432691890.050
cellular calcium ion homeostasisGO:00068741170.049
cellular amine metabolic processGO:0044106410.047
regulation of mapk cascadeGO:00434082620.047
positive regulation of phosphorylationGO:00423273940.047
positive regulation of transportGO:00510503360.045
post embryonic developmentGO:000979120.045
positive regulation of cellular amino acid metabolic processGO:004576430.044
cellular amino acid metabolic processGO:00065201160.044
metal ion transportGO:00300012720.043
positive regulation of cellular amine metabolic processGO:003324070.043
regulation of cellular ketone metabolic processGO:0010565500.043
carbohydrate derivative biosynthetic processGO:19011372070.043
cellular homeostasisGO:00197251960.041
adenylate cyclase modulating g protein coupled receptor signaling pathwayGO:0007188430.040
lipid metabolic processGO:00066293810.040
purine containing compound biosynthetic processGO:0072522880.039
cellular divalent inorganic cation homeostasisGO:00725031280.039
organophosphate biosynthetic processGO:00904071630.039
regulation of transferase activityGO:00513383550.038
cation transmembrane transportGO:00986552380.038
signal transduction by phosphorylationGO:00230142970.038
cyclic nucleotide biosynthetic processGO:0009190610.038
secretion by cellGO:00329402260.038
regulation of kinase activityGO:00435493140.038
cytoplasmic transportGO:00164823790.037
secretionGO:00469032540.037
camp metabolic processGO:0046058610.036
single organism cellular localizationGO:19025803320.035
cellular cation homeostasisGO:00300031630.035
positive regulation of purine nucleotide biosynthetic processGO:1900373380.035
negative regulation of multicellular organismal processGO:00512413170.035
divalent metal ion transportGO:00708381520.035
purine ribonucleotide catabolic processGO:00091544040.035
ribose phosphate biosynthetic processGO:0046390820.034
nucleotide biosynthetic processGO:00091651090.034
regulation of cellular component movementGO:00512703340.033
cation homeostasisGO:00550801890.032
positive regulation of protein kinase activityGO:00458601900.032
response to abiotic stimulusGO:00096283360.032
organic hydroxy compound metabolic processGO:19016151470.032
regulation of cyclic nucleotide biosynthetic processGO:0030802490.031
positive regulation of nucleotide biosynthetic processGO:0030810380.031
positive regulation of hydrolase activityGO:00513453310.030
nucleoside phosphate catabolic processGO:19012924120.030
detection of chemical stimulus involved in sensory perception of smellGO:005091120.030
vesicle mediated transportGO:00161923710.030
multicellular organismal agingGO:001025930.030
divalent inorganic cation transportGO:00725111580.030
detection of stimulusGO:0051606850.030
response to lipidGO:00339932060.029
positive regulation of kinase activityGO:00336742040.029
regulation of secretionGO:00510461940.029
negative regulation of secretion by cellGO:1903531520.029
sensory perception of chemical stimulusGO:0007606380.029
regulation of cell cycleGO:00517263930.029
response to nitrogen compoundGO:19016981840.028
response to other organismGO:00517072610.027
organophosphate catabolic processGO:00464344300.027
response to organic cyclic compoundGO:00140702040.027
calcium ion transportGO:00068161470.027
determination of adult lifespanGO:000834020.027
negative regulation of cell deathGO:00605483450.027
purine containing compound catabolic processGO:00725234110.027
cellular chemical homeostasisGO:00550821800.027
nitrogen compound transportGO:00717051910.026
female gamete generationGO:000729220.026
purine nucleotide biosynthetic processGO:0006164840.026
lipid biosynthetic processGO:00086101770.026
positive regulation of cytosolic calcium ion concentrationGO:0007204820.026
positive regulation of intracellular transportGO:00323881040.025
cellular response to endogenous stimulusGO:00714953360.025
regulation of camp metabolic processGO:0030814520.025
neurological system processGO:00508771630.025
regulation of metal ion transportGO:00109591200.025
ribonucleotide catabolic processGO:00092614050.025
membrane organizationGO:00610242920.025
positive regulation of cytokine productionGO:00018191670.025
maintenance of locationGO:00512351120.024
ribonucleoside triphosphate catabolic processGO:00092033910.024
ras protein signal transductionGO:0007265730.024
rhythmic behaviorGO:000762220.024
nucleotide catabolic processGO:00091664080.023
neuromuscular junction developmentGO:000752830.023
regulation of establishment of protein localizationGO:00702012420.023
regulation of transmembrane transportGO:00347621390.023
cellular response to organic cyclic compoundGO:00714071270.023
regulation of proteolysisGO:00301622930.023
regulation of ion transmembrane transporter activityGO:0032412720.023
protein localization to organelleGO:00333652800.023
memoryGO:000761330.022
negative regulation of secretionGO:0051048580.022
mapk cascadeGO:00001652880.022
metal ion homeostasisGO:00550651690.022
nervous system developmentGO:00073992930.022
innate immune responseGO:00450871780.022
purine nucleotide catabolic processGO:00061954050.022
nucleoside triphosphate catabolic processGO:00091433940.021
purine nucleoside catabolic processGO:00061523980.021
locomotory behaviorGO:000762610.021
nucleoside catabolic processGO:00091644080.021
regulation of immune responseGO:00507762010.021
sensory perceptionGO:00076001030.021
ribonucleoside triphosphate metabolic processGO:00091994120.021
response to organonitrogen compoundGO:00102431560.020
oogenesisGO:004847720.020
protein localization to membraneGO:00726571600.020
regulation of protein kinase activityGO:00458592890.020
positive regulation of transferase activityGO:00513472270.020
muscle system processGO:0003012810.020
positive regulation of immune system processGO:00026842830.020
cytokine productionGO:00018162470.020
purine nucleoside triphosphate metabolic processGO:00091444120.020
regulation of protein serine threonine kinase activityGO:00719001790.019
defense responseGO:00069523150.019
purine ribonucleoside metabolic processGO:00461284370.019
adult locomotory behaviorGO:000834410.019
intracellular protein transportGO:00068862700.019
regulation of ion transmembrane transportGO:00347651320.019
positive regulation of cyclic nucleotide metabolic processGO:0030801490.019
regulation of transmembrane transporter activityGO:0022898740.019
regulation of intracellular transportGO:00323861950.019
regulation of cell migrationGO:00303342890.019
response to external biotic stimulusGO:00432072610.019
response to biotic stimulusGO:00096072760.019
response to oxygen containing compoundGO:19017003690.018
positive regulation of cellular component organizationGO:00511303760.018
detection of chemical stimulusGO:0009593550.018
single organism membrane organizationGO:00448022680.018
regulation of cell cycle processGO:00105642660.018
regulation of protein localizationGO:00328802960.018
purine ribonucleoside triphosphate metabolic processGO:00092054110.018
response to corticotropin releasing hormoneGO:004343510.018
actin filament based processGO:00300292240.018
regulation of transporter activityGO:0032409820.018
purine ribonucleoside catabolic processGO:00461303980.018
muscle contractionGO:0006936730.018
circadian behaviorGO:004851220.018
activation of protein kinase activityGO:0032147900.018
hormone transportGO:0009914680.018
protein oligomerizationGO:00512591730.018
nucleoside triphosphate metabolic processGO:00091414220.017
lipid transportGO:0006869900.017
purine nucleoside triphosphate catabolic processGO:00091463920.017
purine ribonucleoside triphosphate catabolic processGO:00092073910.017
regulation of locomotionGO:00400123290.017
biological adhesionGO:00226103310.017
regulation of hormone levelsGO:00108171250.017
cell cell signalingGO:00072671550.017
Zebrafish
protein targetingGO:00066051870.017
regulation of protein transportGO:00512232130.017
protein catabolic processGO:00301633250.017
sensory perception of smellGO:000760820.017
sequestering of metal ionGO:0051238240.017
positive regulation of nucleoside metabolic processGO:00459791860.017
nucleocytoplasmic transportGO:00069131760.016
inorganic anion transmembrane transportGO:0098661470.016
negative regulation of cellular component organizationGO:00511292350.016
ribonucleoside catabolic processGO:00424544060.016
purine ribonucleoside monophosphate metabolic processGO:00091671860.016
immune effector processGO:00022521590.016
mitotic cell cycle processGO:19030472860.016
positive regulation of mapk cascadeGO:00434101900.016
g protein coupled receptor signaling pathway coupled to cyclic nucleotide second messengerGO:0007187430.016
nuclear transportGO:00511691790.016
regulation of i kappab kinase nf kappab signalingGO:00431221620.016
mitotic cell cycleGO:00002783260.016
regulation of cyclase activityGO:0031279190.016
monovalent inorganic cation transportGO:00156721280.016
negative regulation of cellular protein metabolic processGO:00322693530.016
regulation of cytoplasmic transportGO:19036491490.016
leukocyte activationGO:00453211640.016
negative regulation of apoptotic processGO:00430663160.016
sleepGO:003043120.016
cellular lipid metabolic processGO:00442553030.015
cellular response to nitrogen compoundGO:19016991440.015
reactive oxygen species biosynthetic processGO:190340940.015
glycosyl compound catabolic processGO:19016584130.015
cell adhesionGO:00071553250.015
regulation of calcium ion transportGO:0051924790.015
negative regulation of intracellular signal transductionGO:19025321830.015
negative regulation of phosphorus metabolic processGO:00105632670.015
guanosine containing compound metabolic processGO:19010682440.015
lipid localizationGO:00108761060.015
steroid metabolic processGO:0008202940.015
reactive oxygen species metabolic processGO:0072593750.015
associative learningGO:000830610.015
circulatory system processGO:00030131130.015
positive regulation of proteolysisGO:00458621420.015
establishment of protein localization to organelleGO:00725941720.015
positive regulation of cell cycle processGO:00900681060.015
response to fungusGO:000962040.015
nucleoside phosphate biosynthetic processGO:19012931090.015
negative regulation of cell proliferationGO:00082852280.015
regulation of ion homeostasisGO:2000021730.015
positive regulation of i kappab kinase nf kappab signalingGO:00431231320.015
response to hormoneGO:00097251750.014
positive regulation of protein transportGO:00512221350.014
reactive nitrogen species metabolic processGO:200105730.014
sequestering of calcium ionGO:0051208170.014
regulation of cell divisionGO:00513021160.014
positive regulation of cell migrationGO:00303351720.014
cellular response to organonitrogen compoundGO:00714171240.014
cellular response to dna damage stimulusGO:00069743790.014
regulation of cell motilityGO:20001452990.014
regulation of epithelial cell proliferationGO:00506781130.014
blood circulationGO:00080151130.014
regulation of peptidyl tyrosine phosphorylationGO:00507301080.014
syncytium formation by plasma membrane fusionGO:000076820.014
negative regulation of cellular amine metabolic processGO:003323930.014
negative regulation of programmed cell deathGO:00430693210.014
spermatid differentiationGO:004851540.014
peptidyl tyrosine phosphorylationGO:00181081700.014
regulation of cellular response to stressGO:00801352440.014
anatomical structure formation involved in morphogenesisGO:00486462840.014
positive regulation of cell deathGO:00109422630.014
regulation of cytoskeleton organizationGO:00514931770.014
cell developmentGO:00484683280.014
negative regulation of phosphate metabolic processGO:00459362670.014
epidermal growth factor activated receptor transactivation by g protein coupled receptor signaling pathwayGO:003562540.014
cardiac muscle cell contractionGO:008600340.013
positive regulation of reactive oxygen species biosynthetic processGO:190342820.013
regulation of reactive oxygen species biosynthetic processGO:190342630.013
regulation of response to external stimulusGO:00321012220.013
regulation of anatomical structure morphogenesisGO:00226032860.013
cellular macromolecule catabolic processGO:00442653800.013
negative regulation of cellular amino acid metabolic processGO:004576320.013
regulation of membrane potentialGO:0042391950.013
negative regulation of cytokine productionGO:0001818820.013
response to virusGO:00096151260.013
cell divisionGO:00513011680.013
positive regulation of protein serine threonine kinase activityGO:00719021190.013
regulation of growthGO:00400081650.013
organic anion transportGO:00157111030.013
regulation of sequence specific dna binding transcription factor activityGO:00510902110.013
negative regulation of developmental processGO:00510932470.013
positive regulation of immune responseGO:00507781590.013
small molecule biosynthetic processGO:00442831570.013
protein importGO:00170381300.013
regulation of nucleotide biosynthetic processGO:0030808500.013
growthGO:00400072020.013
peptidyl tyrosine modificationGO:00182121700.013
positive regulation of apoptotic processGO:00430652460.013
negative regulation of protein metabolic processGO:00512483910.013
positive regulation of cellular catabolic processGO:00313312840.013
regulation of endopeptidase activityGO:00525481700.013
regulation of leukocyte activationGO:00026941150.013
i kappab kinase nf kappab signalingGO:00072491660.013
protein secretionGO:0009306980.013
striated muscle contractionGO:0006941520.013
regulation of purine nucleotide catabolic processGO:00331212050.013
small gtpase mediated signal transductionGO:0007264780.013
protein targeting to nucleusGO:00447441040.013
regulation of reactive oxygen species metabolic processGO:2000377410.013
positive regulation of secretionGO:00510471160.012
regulation of cell activationGO:00508651250.012
purine nucleoside monophosphate metabolic processGO:00091261860.012
protein ubiquitinationGO:00165673140.012
guanosine containing compound catabolic processGO:19010692390.012
regulation of protein catabolic processGO:00421761550.012
negative regulation of immune system processGO:00026831360.012
adenylate cyclase inhibiting g protein coupled receptor signaling pathwayGO:0007193220.012
cell activationGO:00017752130.012
actin filament based movementGO:0030048170.012
positive regulation of ion transportGO:0043270870.012
hematopoietic or lymphoid organ developmentGO:00485341860.012
cellular protein catabolic processGO:00442572610.012
negative regulation of insulin secretion involved in cellular response to glucose stimulusGO:006117910.012
neuropeptide signaling pathwayGO:0007218190.012
Zebrafish
circulatory system developmentGO:00723592620.012
single organism cell adhesionGO:00986021790.012
visual behaviorGO:000763220.012
posttranscriptional regulation of gene expressionGO:00106082130.012
transmembrane receptor protein tyrosine kinase signaling pathwayGO:00071691810.012
positive regulation of aldosterone metabolic processGO:003234620.012
immune response activating signal transductionGO:0002757900.012
immune system developmentGO:00025201950.012
negative regulation of locomotionGO:00400131180.012
positive regulation of catabolic processGO:00098963100.012
blood vessel developmentGO:00015681720.012
proteolysis involved in cellular protein catabolic processGO:00516032440.012
protein processingGO:00164852260.012
cellular response to cytokine stimulusGO:00713451810.012
positive regulation of nucleotide catabolic processGO:00308131850.012
blastoderm segmentationGO:000735020.012
positive regulation of cytoplasmic transportGO:1903651820.012
activation of mapk activityGO:0000187450.012
sensory perception of tasteGO:0050909360.012
lymphocyte activationGO:00466491330.012
organelle assemblyGO:00709251760.012
protein maturationGO:00516042330.012
positive regulation of developmental processGO:00510943140.012
segmentationGO:003528240.012
regulation of map kinase activityGO:00434051080.012
cellular component morphogenesisGO:00329893140.012
dephosphorylationGO:00163112090.012
endocytosisGO:00068971590.012
negative regulation of growthGO:0045926970.011
regulation of system processGO:00440571010.011
regulation of lymphocyte activationGO:00512491030.011
myoblast fusionGO:000752010.011
nucleoside monophosphate metabolic processGO:00091231910.011
regulation of intracellular protein transportGO:00331571230.011
t cell activationGO:0042110990.011
regulation of cell adhesionGO:00301551660.011
regulation of adenylate cyclase activityGO:0045761170.011
single organism nuclear importGO:19025931040.011
detection of stimulus involved in sensory perceptionGO:0050906430.011
regulation of nucleotide catabolic processGO:00308112050.011
oocyte developmentGO:004859910.011
cellular response to lipidGO:00713961270.011
nuclear importGO:00511701060.011
apoptotic signaling pathwayGO:00971902680.011
positive regulation of reactive oxygen species metabolic processGO:2000379240.011
plasma membrane organizationGO:00070091150.011
cellular response to disaccharide stimulusGO:007132410.011
ribonucleoside monophosphate metabolic processGO:00091611870.011
actin cytoskeleton organizationGO:00300362070.011
positive regulation of map kinase activityGO:0043406800.011
regulation of cell differentiationGO:00455953930.011
behaviorGO:00076101120.011
cellular response to oxygen containing compoundGO:19017012760.011
receptor transactivationGO:003562440.011
cytokine mediated signaling pathwayGO:00192211090.011
nucleoside monophosphate catabolic processGO:00091251590.011
response to disaccharideGO:003428510.011
positive regulation of cell cycleGO:00457871400.011
regulation of multi organism processGO:00439001570.011
actin mediated cell contractionGO:0070252120.011
endomembrane system organizationGO:00102561960.011
protein modification by small protein conjugationGO:00324463420.011
peptide transportGO:0015833740.011
negative regulation of protein modification processGO:00314002000.011
alcohol metabolic processGO:00060661140.011
spermatid developmentGO:000728640.011
regulation of peptidase activityGO:00525471800.011
hemopoiesisGO:00300971800.011
regulation of immune effector processGO:0002697910.011
regulation of gtpase activityGO:00430871800.011
second messenger mediated signalingGO:0019932780.011
organic hydroxy compound transportGO:0015850630.011
regulation of hormone secretionGO:0046883570.011
positive regulation of programmed cell deathGO:00430682490.011
cell cycle phase transitionGO:00447701730.011
amide transportGO:0042886760.011
receptor metabolic processGO:0043112810.011
regulation of purine nucleotide biosynthetic processGO:1900371500.011
cytokinesisGO:0000910960.011
oocyte differentiationGO:000999420.011
positive regulation of cellular component biogenesisGO:00440891580.011
cellular response to hormone stimulusGO:00328701250.011
negative regulation of catalytic activityGO:00430863350.011
modification dependent protein catabolic processGO:00199412090.011
cardiac muscle contractionGO:0060048340.011
anterior posterior axis specificationGO:000994820.011
positive regulation of purine nucleotide catabolic processGO:00331231850.010
protein localization to nucleusGO:00345041360.010
positive regulation of secretion by cellGO:19035321080.010
phototransductionGO:000760230.010
regulation of protein targetingGO:1903533910.010
proteasomal protein catabolic processGO:00104981760.010
regulation of cysteine type endopeptidase activityGO:20001161270.010
modification dependent macromolecule catabolic processGO:00436322120.010
stress activated mapk cascadeGO:0051403930.010
regulation of lyase activityGO:0051339230.010
endothelial cell proliferationGO:0001935650.010
activation of immune responseGO:00022531140.010
regulation of bindingGO:00510981110.010
regulation of cell growthGO:00015581350.010
glycerolipid metabolic processGO:00464861070.010
response to drugGO:0042493810.010
startle responseGO:000196430.010
cd8 positive alpha beta t cell activationGO:003603730.010
regulation of nucleoside metabolic processGO:00091182090.010
anterior posterior axis specification embryoGO:000859520.010
epithelial cell differentiationGO:00308551410.010
regulation of lipid biosynthetic processGO:0046890470.010
regulation of cellular component biogenesisGO:00440872810.010
response to cytokineGO:00340972320.010
multicellular organismal signalingGO:0035637340.010
regulation of cytokinesisGO:0032465450.010
microtubule based processGO:00070172100.010
single organism carbohydrate metabolic processGO:00447231930.010
dna repairGO:00062811980.010
multicellular organismal homeostasisGO:0048871670.010
Human
negative regulation of lipid metabolic processGO:0045833380.010
regulation of actin filament based processGO:00329701410.010

MC2R disease predictions

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of metabolismDOID:00146672950.034
Human
musculoskeletal system diseaseDOID:172230.026
eye diseaseDOID:56141490.023
nervous system diseaseDOID:8634310.023
sensory system diseaseDOID:00501552030.023
eye and adnexa diseaseDOID:14921500.023
retinal diseaseDOID:56791180.018
inherited metabolic disorderDOID:6552420.016
immune system diseaseDOID:29141550.015
disease of cellular proliferationDOID:145661740.013
organ system cancerDOID:00506861640.013
cancerDOID:1621670.013
retinal degenerationDOID:8466890.013
acquired metabolic diseaseDOID:0060158580.012
Human