Homo sapiens

128 known processes

CAPN3

calpain 3, (p94)

(Aliases: CANP3,MGC4403,nCL-1,MGC11121,LGMD2,p94,LGMD2A,CANPL3,MGC10767,MGC14344)

CAPN3 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
skeletal muscle thin filament assemblyGO:003024030.565
cardiac myofibril assemblyGO:005500330.541
cardiac muscle fiber developmentGO:004873940.246
cellular protein complex assemblyGO:00436231880.108
cellular macromolecular complex assemblyGO:00346223240.106
regulation of transferase activityGO:00513383550.100
ras protein signal transductionGO:0007265730.092
purine ribonucleotide catabolic processGO:00091544040.091
mitotic nuclear divisionGO:00070671190.088
myosin filament assemblyGO:003103420.083
ion transmembrane transportGO:00342203380.077
regulation of protein kinase activityGO:00458592890.075
ribonucleoside catabolic processGO:00424544060.075
regulation of kinase activityGO:00435493140.074
skeletal myofibril assemblyGO:001486630.072
purine nucleoside triphosphate catabolic processGO:00091463920.070
circulatory system developmentGO:00723592620.066
system processGO:00030083490.066
glycosyl compound catabolic processGO:19016584130.064
positive regulation of gtp catabolic processGO:00331261660.063
cellular component morphogenesisGO:00329893140.060
Mouse
cellular amino acid metabolic processGO:00065201160.059
nucleoside triphosphate metabolic processGO:00091414220.058
cell developmentGO:00484683280.058
Mouse
purine nucleotide catabolic processGO:00061954050.056
segmentationGO:003528240.054
muscle hypertrophyGO:0014896140.054
ribonucleoside triphosphate catabolic processGO:00092033910.052
ribonucleoside triphosphate metabolic processGO:00091994120.052
cardiac muscle hypertrophyGO:0003300140.051
positive regulation of ion transportGO:0043270870.050
Mouse
purine nucleoside catabolic processGO:00061523980.049
gtp metabolic processGO:00460392390.049
positive regulation of gtpase activityGO:00435471660.047
amine metabolic processGO:0009308440.047
cardiovascular system developmentGO:00723582620.047
regulation of cellular amino acid metabolic processGO:000652160.047
positive regulation of hydrolase activityGO:00513453310.047
positive regulation of cellular catabolic processGO:00313312840.046
muscle contractionGO:0006936730.046
regulation of cellular amine metabolic processGO:0033238110.046
cell projection organizationGO:00300302520.045
regulation of nucleotide metabolic processGO:00061402690.045
regulation of nucleoside metabolic processGO:00091182090.045
positive regulation of cellular component organizationGO:00511303760.044
response to cytokineGO:00340972320.044
purine ribonucleoside catabolic processGO:00461303980.044
response to calcium ionGO:0051592460.044
Mouse Rat
regulation of cell differentiationGO:00455953930.043
Mouse
post embryonic developmentGO:000979120.043
positive regulation of nucleotide metabolic processGO:00459812300.042
purine ribonucleoside metabolic processGO:00461284370.042
cellular amine metabolic processGO:0044106410.042
regulation of cellular component biogenesisGO:00440872810.042
positive regulation of transportGO:00510503360.042
Mouse
transmembrane transportGO:00550853990.041
organelle fissionGO:00482851490.041
actin filament organizationGO:00070151280.040
cardiac muscle tissue morphogenesisGO:0055008180.040
nucleoside catabolic processGO:00091644080.040
cellular lipid metabolic processGO:00442553030.040
striated muscle myosin thick filament assemblyGO:007168820.039
organelle assemblyGO:00709251760.039
Mouse
female gamete generationGO:000729220.038
regulation of small gtpase mediated signal transductionGO:00510561560.038
dna conformation changeGO:00711031130.038
locomotory behaviorGO:000762610.037
multicellular organismal agingGO:001025930.037
regulation of cell developmentGO:00602841610.037
Mouse
defense responseGO:00069523150.037
dna packagingGO:0006323770.037
regulation of system processGO:00440571010.036
regulation of nucleotide catabolic processGO:00308112050.036
regulation of anatomical structure morphogenesisGO:00226032860.035
oogenesisGO:004847720.035
positive regulation of nucleoside metabolic processGO:00459791860.035
mitotic sister chromatid segregationGO:0000070530.035
regulation of gtpase activityGO:00430871800.034
mitotic cell cycleGO:00002783260.034
gtp catabolic processGO:00061842370.034
positive regulation of ras gtpase activityGO:00323201170.034
determination of adult lifespanGO:000834020.034
negative regulation of cellular component organizationGO:00511292350.034
small gtpase mediated signal transductionGO:0007264780.034
skeletal muscle myosin thick filament assemblyGO:003024120.034
regulation of protein complex assemblyGO:00432541470.034
positive regulation of cellular amine metabolic processGO:003324070.033
regulation of protein localizationGO:00328802960.033
protein localization to organelleGO:00333652800.033
nuclear divisionGO:00002801280.033
lipid metabolic processGO:00066293810.033
cytokinesisGO:0000910960.032
protein catabolic processGO:00301633250.032
cellular ketone metabolic processGO:0042180800.032
response to external biotic stimulusGO:00432072610.032
actin filament based processGO:00300292240.032
Mouse
response to lipidGO:00339932060.031
myosin filament organizationGO:003103320.031
actin cytoskeleton organizationGO:00300362070.031
Mouse
regulation of ras gtpase activityGO:00323181280.030
positive regulation of developmental processGO:00510943140.030
Mouse
positive regulation of cellular amino acid metabolic processGO:004576430.030
nucleoside phosphate catabolic processGO:19012924120.030
metal ion transportGO:00300012720.030
Mouse
cytoplasmic transportGO:00164823790.030
Mouse
regulation of cell morphogenesisGO:00226041530.029
striated muscle hypertrophyGO:0014897140.029
anatomical structure formation involved in morphogenesisGO:00486462840.029
Mouse
positive regulation of cell differentiationGO:00455972110.029
positive regulation of cell deathGO:00109422630.029
biological adhesionGO:00226103310.028
multi organism cellular processGO:00447641560.028
secretionGO:00469032540.028
regulation of cellular ketone metabolic processGO:0010565500.028
cardiac muscle cell differentiationGO:0055007150.028
oxidation reduction processGO:00551143960.028
ribonucleotide catabolic processGO:00092614050.028
response to abiotic stimulusGO:00096283360.028
Mouse
muscle structure developmentGO:0061061980.027
Mouse
sister chromatid segregationGO:0000819540.027
immune responseGO:00069553070.027
nervous system developmentGO:00073992930.027
negative regulation of catalytic activityGO:00430863350.027
cardiac muscle adaptationGO:001488740.026
cellular response to oxygen containing compoundGO:19017012760.026
chromosome segregationGO:00070591140.026
organophosphate catabolic processGO:00464344300.026
regulation of cell projection organizationGO:00313441070.025
regulation of cytoskeleton organizationGO:00514931770.025
negative regulation of protein metabolic processGO:00512483910.025
positive regulation of purine nucleotide catabolic processGO:00331231850.025
positive regulation of apoptotic processGO:00430652460.025
organonitrogen compound biosynthetic processGO:19015662000.025
endomembrane system organizationGO:00102561960.025
mitotic cell cycle processGO:19030472860.025
response to muscle stretchGO:003599430.024
cellular response to organic cyclic compoundGO:00714071270.024
negative regulation of cellular protein metabolic processGO:00322693530.024
regenerationGO:003109940.024
Mouse
positive regulation of transferase activityGO:00513472270.024
cellular macromolecule catabolic processGO:00442653800.024
cellular response to endogenous stimulusGO:00714953360.024
regulation of ion transmembrane transporter activityGO:0032412720.024
regulation of cellular response to stressGO:00801352440.024
protein maturationGO:00516042330.024
positive regulation of catabolic processGO:00098963100.024
response to bacteriumGO:00096171440.024
monocarboxylic acid metabolic processGO:00327871850.023
positive regulation of purine nucleotide metabolic processGO:19005442270.023
cellular component assembly involved in morphogenesisGO:0010927730.023
Mouse
innate immune responseGO:00450871780.023
response to biotic stimulusGO:00096072760.022
dephosphorylationGO:00163112090.022
positive regulation of cellular component movementGO:00512721810.022
inorganic cation transmembrane transportGO:00986621940.022
heart morphogenesisGO:0003007480.022
anion transportGO:00068201610.022
regulation of purine nucleotide metabolic processGO:19005422640.022
regulation of cell cycleGO:00517263930.022
regulation of mitosisGO:0007088630.022
regulation of gtp catabolic processGO:00331241800.022
negative regulation of phosphorus metabolic processGO:00105632670.022
regulation of establishment of protein localizationGO:00702012420.022
positive regulation of programmed cell deathGO:00430682490.021
protein modification by small protein conjugationGO:00324463420.021
response to hormoneGO:00097251750.021
protein processingGO:00164852260.021
positive regulation of sequence specific dna binding transcription factor activityGO:00510911310.021
single organism cellular localizationGO:19025803320.021
Mouse
purine ribonucleoside triphosphate metabolic processGO:00092054110.021
response to oxygen containing compoundGO:19017003690.020
regulation of secretionGO:00510461940.020
positive regulation of secretion by cellGO:19035321080.020
regulation of reactive oxygen species metabolic processGO:2000377410.020
adult locomotory behaviorGO:000834410.019
positive regulation of nucleotide catabolic processGO:00308131850.019
regulation of response to external stimulusGO:00321012220.019
Mouse
response to growth factorGO:00708482050.019
cellular protein catabolic processGO:00442572610.019
response to other organismGO:00517072610.019
regulation of ras protein signal transductionGO:00465781550.019
actin polymerization or depolymerizationGO:0008154560.019
guanosine containing compound catabolic processGO:19010692390.019
memoryGO:000761330.019
positive regulation of secretionGO:00510471160.019
cell morphogenesisGO:00009022960.019
regulation of transmembrane transporter activityGO:0022898740.018
regulation of proteolysisGO:00301622930.018
Mouse
regulation of reactive oxygen species biosynthetic processGO:190342630.018
maintenance of locationGO:00512351120.018
protein oligomerizationGO:00512591730.018
secretion by cellGO:00329402260.018
neuromuscular junction developmentGO:000752830.018
nucleoside triphosphate catabolic processGO:00091433940.018
neurological system processGO:00508771630.018
reactive oxygen species metabolic processGO:0072593750.018
regulation of protein secretionGO:0050708860.018
positive regulation of ion transmembrane transporter activityGO:0032414290.018
cellular response to dna damage stimulusGO:00069743790.018
regulation of actin filament polymerizationGO:0030833500.018
reactive oxygen species biosynthetic processGO:190340940.018
actomyosin structure organizationGO:0031032590.018
Mouse
blastoderm segmentationGO:000735020.018
regulation of cell cycle processGO:00105642660.018
viral processGO:00160321460.017
cell projection assemblyGO:00300311260.017
regulation of cellular component movementGO:00512703340.017
single organism carbohydrate metabolic processGO:00447231930.017
oocyte differentiationGO:000999420.017
cell projection morphogenesisGO:00488581290.017
oocyte developmentGO:004859910.017
muscle fiber developmentGO:0048747160.017
Mouse
protein complex disassemblyGO:0043241520.017
positive regulation of immune system processGO:00026842830.017
negative regulation of phosphate metabolic processGO:00459362670.017
negative regulation of cellular amino acid metabolic processGO:004576320.017
regulation of protein maturationGO:19033171500.017
protein ubiquitinationGO:00165673140.017
generation of neuronsGO:00486991520.017
regulation of rho protein signal transductionGO:0035023790.017
positive regulation of immune responseGO:00507781590.017
detection of muscle stretchGO:003599520.017
regulation of cellular component sizeGO:0032535820.017
cardiocyte differentiationGO:0035051230.017
mapk cascadeGO:00001652880.017
rho protein signal transductionGO:0007266260.017
interspecies interaction between organismsGO:00444191560.017
negative regulation of hydrolase activityGO:00513461820.017
positive regulation of phosphorylationGO:00423273940.016
muscle cell developmentGO:0055001290.016
Mouse
spermatid differentiationGO:004851540.016
organic anion transportGO:00157111030.016
striated muscle contractionGO:0006941520.016
regulation of purine nucleotide catabolic processGO:00331212050.016
negative regulation of intracellular signal transductionGO:19025321830.016
muscle organ developmentGO:0007517560.016
Mouse
negative regulation of transcription from rna polymerase ii promoterGO:00001222810.016
positive regulation of rho gtpase activityGO:0032321560.016
negative regulation of developmental processGO:00510932470.016
regulation of protein transportGO:00512232130.016
positive regulation of protein phosphorylationGO:00019343130.016
purine ribonucleoside triphosphate catabolic processGO:00092073910.016
actin filament cappingGO:005169340.016
microtubule cytoskeleton organizationGO:00002261760.016
nucleotide catabolic processGO:00091664080.016
hindbrain developmentGO:003090230.016
negative regulation of cellular amine metabolic processGO:003323930.016
reactive nitrogen species metabolic processGO:200105730.016
organophosphate biosynthetic processGO:00904071630.015
peripheral nervous system developmentGO:000742220.015
regulation of protein processingGO:00706131500.015
negative regulation of protein processingGO:00109551420.015
negative regulation of organelle organizationGO:00106391260.015
positive regulation of protein kinase activityGO:00458601900.015
posttranscriptional regulation of gene expressionGO:00106082130.015
enzyme linked receptor protein signaling pathwayGO:00071673030.015
response to electrical stimulusGO:005160210.015
protein homooligomerizationGO:00512601000.015
cation transmembrane transportGO:00986552380.015
negative regulation of multicellular organismal processGO:00512413170.015
organ morphogenesisGO:00098871470.015
positive regulation of cell projection organizationGO:0031346640.015
response to inorganic substanceGO:00100351270.015
Mouse Rat
cellular response to cytokine stimulusGO:00713451810.015
cardiac muscle cell developmentGO:005501350.015
regulation of anatomical structure sizeGO:00900661010.015
purine ribonucleoside monophosphate catabolic processGO:00091691580.015
immune effector processGO:00022521590.015
regulation of nervous system developmentGO:0051960880.015
cellular response to glucocorticoid stimulusGO:007138540.015
cellular component disassemblyGO:0022411920.015
proteolysis involved in cellular protein catabolic processGO:00516032440.015
carbohydrate metabolic processGO:00059752070.015
heart developmentGO:0007507950.015
chemical homeostasisGO:00488783060.015
Mouse
negative regulation of programmed cell deathGO:00430693210.015
regulation of secretion by cellGO:19035301770.015
cell fate determinationGO:000170930.015
muscle hypertrophy in response to stressGO:000329940.015
negative regulation of protein modification processGO:00314002000.014
regulation of ion transportGO:00432691890.014
Mouse
positive regulation of kinase activityGO:00336742040.014
regulation of immune responseGO:00507762010.014
inner ear morphogenesisGO:004247240.014
epithelium developmentGO:00604292270.014
regulation of endopeptidase activityGO:00525481700.014
regulation of multi organism processGO:00439001570.014
cell junction organizationGO:0034330790.014
membrane organizationGO:00610242920.014
Mouse
spermatid developmentGO:000728640.014
symbiosis encompassing mutualism through parasitismGO:00444031560.014
apoptotic signaling pathwayGO:00971902680.014
rhythmic behaviorGO:000762220.014
regulation of rho gtpase activityGO:0032319660.014
neurogenesisGO:00220081690.014
regulation of cell morphogenesis involved in differentiationGO:0010769830.014
neuron projection developmentGO:00311751060.014
tissue morphogenesisGO:0048729960.014
viral life cycleGO:00190581320.014
circadian behaviorGO:004851220.014
regulation of peptidase activityGO:00525471800.014
negative regulation of apoptotic processGO:00430663160.014
anterior posterior axis specificationGO:000994820.014
compound eye developmentGO:004874910.014
regulation of actin filament based processGO:00329701410.014
modification dependent macromolecule catabolic processGO:00436322120.014
regulation of dna metabolic processGO:00510521530.014
regulation of membrane potentialGO:0042391950.014
muscle system processGO:0003012810.014
positive regulation of reactive oxygen species biosynthetic processGO:190342820.013
response to nitrogen compoundGO:19016981840.013
response to organonitrogen compoundGO:00102431560.013
cell growthGO:00160491600.013
negative regulation of cell cycleGO:00457861930.013
modification dependent protein catabolic processGO:00199412090.013
phospholipid metabolic processGO:0006644990.013
macromolecular complex disassemblyGO:0032984600.013
cellular cation homeostasisGO:00300031630.013
Mouse
circulatory system processGO:00030131130.013
cardiac muscle contractionGO:0060048340.013
rna processingGO:00063962550.013
negative regulation of cellular component movementGO:00512711060.013
monovalent inorganic cation transportGO:00156721280.013
regulation of cell migrationGO:00303342890.013
regulation of growthGO:00400081650.013
Mouse
anterior posterior axis specification embryoGO:000859520.013
protein polymerizationGO:0051258710.013
regulation of transporter activityGO:0032409820.013
negative regulation of proteolysisGO:00458611320.013
purine containing compound catabolic processGO:00725234110.013
signal transduction by phosphorylationGO:00230142970.013
positive regulation of mapk cascadeGO:00434101900.012
response to organic cyclic compoundGO:00140702040.012
cell divisionGO:00513011680.012
carbohydrate derivative biosynthetic processGO:19011372070.012
negative regulation of protein maturationGO:19033181420.012
sarcomere organizationGO:004521480.012
Mouse
syncytium formation by plasma membrane fusionGO:000076820.012
motor neuron axon guidanceGO:000804520.012
response to oxygen levelsGO:00704821000.012
regulation of cell motilityGO:20001452990.012
proteasomal protein catabolic processGO:00104981760.012
nitrogen compound transportGO:00717051910.012
cell part morphogenesisGO:00329901370.012
protein targetingGO:00066051870.012
response to axon injuryGO:004867810.012
positive regulation of locomotionGO:00400171860.012
neuron developmentGO:00486661130.012
small molecule biosynthetic processGO:00442831570.012
regulation of cell adhesionGO:00301551660.012
positive regulation of synaptic transmissionGO:005080640.012
negative regulation of cell deathGO:00605483450.012
regulation of locomotionGO:00400123290.012
cellular chemical homeostasisGO:00550821800.012
Mouse
tripartite regional subdivisionGO:000735120.012
cytokinesis completion of separationGO:000710930.012
intracellular protein transportGO:00068862700.012
metencephalon developmentGO:002203720.012
cell cycle phase transitionGO:00447701730.012
negative regulation of catabolic processGO:00098951040.012
negative regulation of viral release from host cellGO:1902187120.012
cellular response to organonitrogen compoundGO:00714171240.012
positive regulation of neurogenesisGO:0050769490.012
cell adhesionGO:00071553250.012
regulation of cysteine type endopeptidase activityGO:20001161270.012
activation of immune responseGO:00022531140.012
nuclear transportGO:00511691790.012
endosomal transportGO:00161971290.012
positive regulation of reactive oxygen species metabolic processGO:2000379240.012
growthGO:00400072020.012
Mouse
negative regulation of peptidase activityGO:0010466910.011
response to mechanical stimulusGO:0009612510.011
regulation of synaptic plasticityGO:004816730.011
response to dexamethasoneGO:007154810.011
tissue regenerationGO:004224630.011
Mouse
microtubule based processGO:00070172100.011
regulation of neural precursor cell proliferationGO:200017740.011
lipid transportGO:0006869900.011
regulation of neuron differentiationGO:0045664700.011
cellular response to external stimulusGO:00714961110.011
associative learningGO:000830610.011
regulation of dephosphorylationGO:0035303960.011
regulation of mitotic cell cycleGO:00073461890.011
regulation of response to dna damage stimulusGO:2001020940.011
cell activationGO:00017752130.011
Mouse
response to transforming growth factor betaGO:0071559940.011
response to radiationGO:00093141510.011
lipid biosynthetic processGO:00086101770.011
chromatin modificationGO:00165682980.011
striated muscle cell differentiationGO:0051146430.011
Mouse
nucleoside monophosphate metabolic processGO:00091231910.011
limbic system developmentGO:002176130.011
covalent chromatin modificationGO:00165692540.011
cellular response to growth factor stimulusGO:00713631970.011
fatty acid metabolic processGO:00066311150.011
negative regulation of phosphorylationGO:00423261740.011
muscle tissue morphogenesisGO:0060415190.011
rna interferenceGO:001624640.011
proteasome mediated ubiquitin dependent protein catabolic processGO:00431611560.011
regulation of cytokine productionGO:00018172320.011
photoreceptor cell differentiationGO:004653020.011
neuroblast proliferationGO:000740540.011
regulation of ion transmembrane transportGO:00347651320.011
peptidyl lysine modificationGO:00182051440.011
regulation of cell growthGO:00015581350.011
negative regulation of endopeptidase activityGO:0010951840.011
myoblast fusionGO:000752010.011
sensory perception of painGO:001923340.011
cell cell junction organizationGO:0045216690.011
protein acylationGO:00435431380.011
sex determinationGO:000753030.011
stem cell divisionGO:001714520.011
matingGO:000761810.011
heart contractionGO:0060047620.011
somitogenesisGO:000175620.011
regulation of cytoplasmic transportGO:19036491490.011
Mouse
regulation of meiotic cell cycleGO:005144540.011
cellular response to hormone stimulusGO:00328701250.011
detection of mechanical stimulusGO:005098240.011
negative regulation of cell proliferationGO:00082852280.011
sequestering of calcium ionGO:0051208170.011
response to drugGO:0042493810.011
Rat
neurotransmitter secretionGO:000726940.011
tissue migrationGO:00901301190.011
glycoprotein metabolic processGO:00091001100.011
actin mediated cell contractionGO:0070252120.011
response to nutrient levelsGO:0031667810.010
sulfur compound metabolic processGO:00067901010.010
regulation of nuclear divisionGO:0051783650.010
negative regulation of synaptic transmissionGO:005080520.010
negative regulation of cell differentiationGO:00455961710.010
rna splicingGO:00083801310.010
actin filament polymerizationGO:0030041450.010
purine nucleoside triphosphate metabolic processGO:00091444120.010
positive regulation of cellular component biogenesisGO:00440891580.010
sequestering of metal ionGO:0051238240.010
meiosis iGO:000712740.010
angiogenesisGO:00015251470.010
mrna metabolic processGO:00160711750.010
cardiac muscle cell contractionGO:008600340.010
regulation of protein serine threonine kinase activityGO:00719001790.010
wnt signaling pathwayGO:00160551560.010
cellular response to nitrogen compoundGO:19016991440.010
chromosome condensationGO:0030261150.010
post embryonic organ developmentGO:004856910.010
thymus developmentGO:004853830.010
purine ribonucleoside monophosphate metabolic processGO:00091671860.010
cell morphogenesis involved in differentiationGO:00009041440.010
negative regulation of cellular catabolic processGO:0031330830.010
chemotaxisGO:00069351570.010
action potentialGO:0001508340.010

CAPN3 disease predictions

DiseaseDO term IDSizeProbabilityFunc Analog Org
muscular dystrophyDOID:9884510.590
muscular diseaseDOID:00800001140.590
musculoskeletal system diseaseDOID:172230.590
myopathyDOID:4231040.590
muscle tissue diseaseDOID:661130.590
limb girdle muscular dystrophyDOID:11724250.425
hypertrophic cardiomyopathyDOID:11984210.103
intrinsic cardiomyopathyDOID:0060036500.103
heart diseaseDOID:114680.103
cardiovascular system diseaseDOID:12871060.103
cardiomyopathyDOID:0050700500.103
dilated cardiomyopathyDOID:12930320.065
disease of metabolismDOID:00146672950.061
inherited metabolic disorderDOID:6552420.037
nervous system diseaseDOID:8634310.023
central nervous system diseaseDOID:3311860.023
sensory system diseaseDOID:00501552030.021
neurodegenerative diseaseDOID:12891020.016
cancerDOID:1621670.014
disease of cellular proliferationDOID:145661740.014
organ system cancerDOID:00506861640.014
eye and adnexa diseaseDOID:14921500.013
eye diseaseDOID:56141490.013
brain diseaseDOID:936730.012
disease of mental healthDOID:150700.012
connective tissue diseaseDOID:651090.011
amino acid metabolic disorderDOID:9252500.011
retinal diseaseDOID:56791180.010