Homo sapiens

29 known processes

KLHL8

kelch-like 8 (Drosophila)

(Aliases: FLJ46304,KIAA1378)

KLHL8 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
post embryonic developmentGO:000979120.142
proteolysis involved in cellular protein catabolic processGO:00516032440.101
protein catabolic processGO:00301633250.075
protein modification by small protein conjugationGO:00324463420.075
modification dependent protein catabolic processGO:00199412090.063
cellular macromolecule catabolic processGO:00442653800.055
neuromuscular junction developmentGO:000752830.053
negative regulation of programmed cell deathGO:00430693210.052
Human
negative regulation of apoptotic processGO:00430663160.051
Human
locomotory behaviorGO:000762610.049
female gamete generationGO:000729220.045
proteasome mediated ubiquitin dependent protein catabolic processGO:00431611560.045
Human
negative regulation of cell deathGO:00605483450.044
Human
regulation of cell cycleGO:00517263930.043
Human
protein ubiquitinationGO:00165673140.041
positive regulation of cellular catabolic processGO:00313312840.041
positive regulation of catabolic processGO:00098963100.040
ras protein signal transductionGO:0007265730.039
single organism cellular localizationGO:19025803320.038
Human
modification dependent macromolecule catabolic processGO:00436322120.038
ubiquitin dependent protein catabolic processGO:00065112060.038
negative regulation of protein metabolic processGO:00512483910.038
Human
cellular amino acid metabolic processGO:00065201160.037
multicellular organismal agingGO:001025930.037
negative regulation of cellular protein metabolic processGO:00322693530.035
Human
mitotic cell cycleGO:00002783260.035
adult locomotory behaviorGO:000834410.034
oogenesisGO:004847720.034
determination of adult lifespanGO:000834020.034
cellular protein catabolic processGO:00442572610.034
chemical homeostasisGO:00488783060.033
Human
metal ion transportGO:00300012720.032
Human
vesicle targeting rough er to cis golgiGO:004820720.031
Human
ion homeostasisGO:00508012300.030
Human
regulation of cellular amino acid metabolic processGO:000652160.029
cellular response to dna damage stimulusGO:00069743790.029
microtubule based processGO:00070172100.029
regulation of cell cycle processGO:00105642660.028
Human
microtubule cytoskeleton organizationGO:00002261760.028
posttranscriptional regulation of gene expressionGO:00106082130.028
Human
response to abiotic stimulusGO:00096283360.027
regulation of proteolysisGO:00301622930.027
regulation of response to external stimulusGO:00321012220.026
positive regulation of cellular component organizationGO:00511303760.026
mrna metabolic processGO:00160711750.025
growthGO:00400072020.025
positive regulation of cellular amino acid metabolic processGO:004576430.025
regulation of cellular protein catabolic processGO:1903362960.025
vesicle mediated transportGO:00161923710.025
Human
organelle fissionGO:00482851490.024
cell developmentGO:00484683280.024
regulation of cellular amine metabolic processGO:0033238110.023
regulation of protein maturationGO:19033171500.023
nervous system developmentGO:00073992930.023
negative regulation of intracellular signal transductionGO:19025321830.023
segmentationGO:003528240.023
cellular ketone metabolic processGO:0042180800.023
regulation of meiotic cell cycleGO:005144540.022
response to radiationGO:00093141510.022
rna processingGO:00063962550.022
membrane organizationGO:00610242920.022
Human
mitotic cell cycle processGO:19030472860.021
positive regulation of cellular amine metabolic processGO:003324070.021
protein processingGO:00164852260.021
stem cell divisionGO:001714520.021
positive regulation of hydrolase activityGO:00513453310.020
apoptotic signaling pathwayGO:00971902680.020
small gtpase mediated signal transductionGO:0007264780.020
protein maturationGO:00516042330.020
cytoplasmic transportGO:00164823790.020
Human
dephosphorylationGO:00163112090.020
purine containing compound catabolic processGO:00725234110.019
copii vesicle coatingGO:004820820.019
Human
protein modification by small protein removalGO:0070646920.019
macromolecule methylationGO:0043414970.019
regulation of cell growthGO:00015581350.019
organ formationGO:004864530.018
cellular lipid metabolic processGO:00442553030.018
positive regulation of cell deathGO:00109422630.018
hindbrain developmentGO:003090230.018
anterior posterior axis specificationGO:000994820.018
regulation of cellular ketone metabolic processGO:0010565500.018
amine metabolic processGO:0009308440.018
negative regulation of cell proliferationGO:00082852280.018
protein oligomerizationGO:00512591730.018
protein ubiquitination involved in ubiquitin dependent protein catabolic processGO:0042787370.018
positive regulation of synaptic transmissionGO:005080640.018
lipid metabolic processGO:00066293810.018
cell morphogenesisGO:00009022960.018
regulation of growthGO:00400081650.018
immune responseGO:00069553070.018
negative regulation of phosphorus metabolic processGO:00105632670.017
oocyte developmentGO:004859910.017
nucleoside catabolic processGO:00091644080.017
methylationGO:00322591060.017
positive regulation of programmed cell deathGO:00430682490.017
cellular amine metabolic processGO:0044106410.017
intrinsic apoptotic signaling pathwayGO:00971931270.017
defense responseGO:00069523150.017
purine nucleoside triphosphate catabolic processGO:00091463920.017
purine nucleoside triphosphate metabolic processGO:00091444120.017
response to oxygen containing compoundGO:19017003690.017
central nervous system developmentGO:00074171230.017
protein localization to organelleGO:00333652800.017
Human
positive regulation of cell proliferationGO:00082843010.017
proteasomal protein catabolic processGO:00104981760.016
Human
cell divisionGO:00513011680.016
Human
negative regulation of catalytic activityGO:00430863350.016
negative regulation of proteolysisGO:00458611320.016
positive regulation of meiotic cell cycleGO:005144620.016
regulation of protein catabolic processGO:00421761550.016
positive regulation of nucleotide metabolic processGO:00459812300.016
oocyte differentiationGO:000999420.016
ribonucleoside triphosphate catabolic processGO:00092033910.016
regulation of nucleotide metabolic processGO:00061402690.016
compound eye developmentGO:004874910.016
system processGO:00030083490.016
Human
cellular protein complex assemblyGO:00436231880.016
positive regulation of purine nucleotide metabolic processGO:19005442270.016
embryo developmentGO:00097901230.016
regulation of purine nucleotide metabolic processGO:19005422640.015
memoryGO:000761330.015
positive regulation of organelle organizationGO:00106381950.015
neurological system processGO:00508771630.015
regulation of cellular component biogenesisGO:00440872810.015
ion transmembrane transportGO:00342203380.015
negative regulation of hydrolase activityGO:00513461820.015
anatomical structure formation involved in morphogenesisGO:00486462840.015
blastoderm segmentationGO:000735020.015
protein localization to nucleusGO:00345041360.015
actin filament based processGO:00300292240.015
regulation of protein processingGO:00706131500.015
ribonucleoside catabolic processGO:00424544060.015
rho protein signal transductionGO:0007266260.015
regulation of protein localizationGO:00328802960.015
regulation of purine nucleotide catabolic processGO:00331212050.014
peripheral nervous system developmentGO:000742220.014
negative regulation of phosphate metabolic processGO:00459362670.014
rna splicingGO:00083801310.014
nucleotide catabolic processGO:00091664080.014
purine nucleoside catabolic processGO:00061523980.014
positive regulation of immune system processGO:00026842830.014
negative regulation of protein maturationGO:19033181420.014
purine ribonucleoside metabolic processGO:00461284370.014
positive regulation of apoptotic processGO:00430652460.014
negative regulation of protein modification processGO:00314002000.014
regulation of apoptotic signaling pathwayGO:20012331750.014
purine ribonucleoside triphosphate catabolic processGO:00092073910.014
regulation of kinase activityGO:00435493140.014
trophectodermal cell differentiationGO:000182930.014
metencephalon developmentGO:002203720.014
negative regulation of cell cycleGO:00457861930.014
regulation of protein transportGO:00512232130.014
regulation of protein kinase activityGO:00458592890.014
regulation of intracellular transportGO:00323861950.014
single organism membrane organizationGO:00448022680.014
Human
negative regulation of cellular component organizationGO:00511292350.014
glycosyl compound catabolic processGO:19016584130.014
secretionGO:00469032540.014
regulation of anatomical structure morphogenesisGO:00226032860.013
cell projection organizationGO:00300302520.013
behaviorGO:00076101120.013
positive regulation of nucleotide catabolic processGO:00308131850.013
tube developmentGO:00352951250.013
Human
oxidation reduction processGO:00551143960.013
organelle localizationGO:0051640840.013
Human
innate immune responseGO:00450871780.013
transmembrane transportGO:00550853990.013
purine nucleotide catabolic processGO:00061954050.013
positive regulation of transportGO:00510503360.013
ribonucleoside triphosphate metabolic processGO:00091994120.013
mitotic cell cycle phase transitionGO:00447721620.013
protein deubiquitinationGO:0016579790.013
negative regulation of protein processingGO:00109551420.013
protein targetingGO:00066051870.013
regulation of small gtpase mediated signal transductionGO:00510561560.013
positive regulation of purine nucleotide catabolic processGO:00331231850.013
positive regulation of cell cycle processGO:00900681060.013
inorganic cation transmembrane transportGO:00986621940.013
organophosphate catabolic processGO:00464344300.013
purine ribonucleoside triphosphate metabolic processGO:00092054110.012
cellular response to oxygen containing compoundGO:19017012760.012
purine ribonucleoside catabolic processGO:00461303980.012
cell cycle phase transitionGO:00447701730.012
regulation of endopeptidase activityGO:00525481700.012
cellular macromolecular complex assemblyGO:00346223240.012
cytokinesisGO:0000910960.012
Human
organelle assemblyGO:00709251760.012
positive regulation of cell cycleGO:00457871400.012
cerebellum developmentGO:002154920.012
cell growthGO:00160491600.012
guanosine containing compound metabolic processGO:19010682440.012
cellular component morphogenesisGO:00329893140.012
regulation of ras protein signal transductionGO:00465781550.012
translationGO:00064121320.012
Human
response to biotic stimulusGO:00096072760.012
rhythmic behaviorGO:000762220.012
negative regulation of growthGO:0045926970.012
positive regulation of protein catabolic processGO:0045732750.012
histone modificationGO:00165702510.012
response to growth factorGO:00708482050.012
mitochondrion organizationGO:00070051560.012
endosomal transportGO:00161971290.012
Human
morphogenesis of embryonic epitheliumGO:001633140.012
regulation of cellular response to stressGO:00801352440.012
negative regulation of developmental processGO:00510932470.012
regulation of cell cycle phase transitionGO:19019871260.012
positive regulation of gtp catabolic processGO:00331261660.012
signal transduction by phosphorylationGO:00230142970.012
regulation of establishment of protein localizationGO:00702012420.012
purine ribonucleotide catabolic processGO:00091544040.012
chemotaxisGO:00069351570.012
meiosis iGO:000712740.012
positive regulation of proteolysisGO:00458621420.012
response to external biotic stimulusGO:00432072610.012
positive regulation of developmental processGO:00510943140.012
positive regulation of nucleoside metabolic processGO:00459791860.012
negative regulation of protein phosphorylationGO:00019331400.012
epithelium developmentGO:00604292270.011
Human
establishment or maintenance of apical basal cell polarityGO:003508820.011
divalent inorganic cation homeostasisGO:00725071360.011
cellular homeostasisGO:00197251960.011
regulation of nucleoside metabolic processGO:00091182090.011
cation transportGO:00068123310.011
Human
negative regulation of transcription from rna polymerase ii promoterGO:00001222810.011
nucleoside phosphate catabolic processGO:19012924120.011
neurotransmitter secretionGO:000726940.011
regulation of gtpase activityGO:00430871800.011
ribonucleoprotein complex assemblyGO:0022618780.011
cerebral cortex cell migrationGO:002179530.011
response to cytokineGO:00340972320.011
regulation of nucleotide catabolic processGO:00308112050.011
gtp metabolic processGO:00460392390.011
nuclear transportGO:00511691790.011
visual behaviorGO:000763220.011
regenerationGO:003109940.011
enzyme linked receptor protein signaling pathwayGO:00071673030.011
long term memoryGO:000761620.011
regulation of cell developmentGO:00602841610.011
monovalent inorganic cation transportGO:00156721280.011
Human
neurogenesisGO:00220081690.011
associative learningGO:000830610.011
nuclear divisionGO:00002801280.011
blastocyst developmentGO:000182430.011
lipid biosynthetic processGO:00086101770.011
reactive oxygen species biosynthetic processGO:190340940.011
intracellular protein transportGO:00068862700.011
ribonucleotide catabolic processGO:00092614050.011
regulation of ion transportGO:00432691890.011
organ morphogenesisGO:00098871470.011
Human
metal ion homeostasisGO:00550651690.011
mapk cascadeGO:00001652880.011
gtp catabolic processGO:00061842370.011
regulation of synaptic plasticityGO:004816730.011
head developmentGO:00603221080.011
negative regulation of phosphorylationGO:00423261740.011
cell substrate adhesionGO:00315891320.010
positive regulation of cellular component biogenesisGO:00440891580.010
regulation of cell differentiationGO:00455953930.010
negative regulation of immune system processGO:00026831360.010
negative regulation of multicellular organismal processGO:00512413170.010
cellular cation homeostasisGO:00300031630.010
cell cell signalingGO:00072671550.010
response to other organismGO:00517072610.010
golgi vesicle transportGO:0048193800.010
Human
spermatid developmentGO:000728640.010
cation homeostasisGO:00550801890.010
sensory perceptionGO:00076001030.010
blastocyst formationGO:000182530.010
regulation of mitotic cell cycleGO:00073461890.010
chromosome passenger complex localization to spindle midzoneGO:003585310.010
Human
tripartite regional subdivisionGO:000735120.010
cation transmembrane transportGO:00986552380.010
regulation of cytoplasmic transportGO:19036491490.010
nitrogen compound transportGO:00717051910.010
regulation of intracellular protein transportGO:00331571230.010
secretion by cellGO:00329402260.010

KLHL8 disease predictions

DiseaseDO term IDSizeProbabilityFunc Analog Org
musculoskeletal system diseaseDOID:172230.025
disease of metabolismDOID:00146672950.020
disease of cellular proliferationDOID:145661740.017
sensory system diseaseDOID:00501552030.016
nervous system diseaseDOID:8634310.016
eye and adnexa diseaseDOID:14921500.014
central nervous system diseaseDOID:3311860.013
cancerDOID:1621670.013
organ system cancerDOID:00506861640.013
muscular diseaseDOID:00800001140.012
muscle tissue diseaseDOID:661130.012
eye diseaseDOID:56141490.012
neurodegenerative diseaseDOID:12891020.010