Homo sapiens

7 known processes

GRHL2

grainyhead-like 2 (Drosophila)

(Aliases: MGC149295,MGC149294,BOM,TFCP2L3,FLJ11172,FLJ13782,DFNA28)

GRHL2 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
epithelial cell differentiationGO:00308551410.235
epithelium developmentGO:00604292270.222
Zebrafish
actin filament based processGO:00300292240.104
Human
post embryonic developmentGO:000979120.076
regulation of actin filament based processGO:00329701410.075
Human
actin cytoskeleton organizationGO:00300362070.068
Human
morphogenesis of embryonic epitheliumGO:001633140.061
negative regulation of transcription from rna polymerase ii promoterGO:00001222810.056
endomembrane system organizationGO:00102561960.055
rho protein signal transductionGO:0007266260.052
system processGO:00030083490.051
negative regulation of developmental processGO:00510932470.050
cell morphogenesisGO:00009022960.049
regulation of cell differentiationGO:00455953930.049
neural crest cell developmentGO:001403230.048
negative regulation of multicellular organismal processGO:00512413170.047
ras protein signal transductionGO:0007265730.045
nucleoside phosphate catabolic processGO:19012924120.044
small gtpase mediated signal transductionGO:0007264780.043
regulation of anatomical structure morphogenesisGO:00226032860.042
cell developmentGO:00484683280.042
Zebrafish
negative regulation of cell proliferationGO:00082852280.039
sex determinationGO:000753030.039
regulation of cellular amine metabolic processGO:0033238110.038
cardiac muscle cell contractionGO:008600340.038
embryonic epithelial tube formationGO:000183840.038
cellular component morphogenesisGO:00329893140.038
purine nucleoside triphosphate metabolic processGO:00091444120.037
multicellular organismal agingGO:001025930.037
positive regulation of phosphorylationGO:00423273940.037
negative regulation of cellular component organizationGO:00511292350.037
anatomical structure formation involved in morphogenesisGO:00486462840.037
cellular ketone metabolic processGO:0042180800.037
purine ribonucleoside triphosphate catabolic processGO:00092073910.036
negative regulation of cell differentiationGO:00455961710.036
regulation of cell cycleGO:00517263930.035
cellular amino acid metabolic processGO:00065201160.035
segmentationGO:003528240.034
organophosphate catabolic processGO:00464344300.034
regulation of cellular amino acid metabolic processGO:000652160.034
nucleoside triphosphate catabolic processGO:00091433940.034
determination of adult lifespanGO:000834020.034
positive regulation of hydrolase activityGO:00513453310.034
glycosyl compound catabolic processGO:19016584130.033
purine containing compound catabolic processGO:00725234110.032
vesicle mediated transportGO:00161923710.032
cardiovascular system developmentGO:00723582620.032
purine nucleoside triphosphate catabolic processGO:00091463920.032
regulation of cytoskeleton organizationGO:00514931770.031
Human
amine metabolic processGO:0009308440.031
positive regulation of catabolic processGO:00098963100.031
purine ribonucleotide catabolic processGO:00091544040.031
regulation of epithelial cell proliferationGO:00506781130.030
biological adhesionGO:00226103310.030
purine ribonucleoside catabolic processGO:00461303980.030
actin mediated cell contractionGO:0070252120.030
skin developmentGO:0043588760.029
keratinocyte differentiationGO:0030216360.029
circulatory system developmentGO:00723592620.029
purine ribonucleoside triphosphate metabolic processGO:00092054110.029
heart developmentGO:0007507950.028
enzyme linked receptor protein signaling pathwayGO:00071673030.028
ribonucleoside catabolic processGO:00424544060.028
negative regulation of cell deathGO:00605483450.028
cellular amine metabolic processGO:0044106410.028
ribonucleoside triphosphate catabolic processGO:00092033910.028
regulation of cellular ketone metabolic processGO:0010565500.028
purine ribonucleoside metabolic processGO:00461284370.027
ribonucleoside triphosphate metabolic processGO:00091994120.027
regulation of cellular component movementGO:00512703340.027
purine nucleotide catabolic processGO:00061954050.027
cellular response to endogenous stimulusGO:00714953360.027
regulation of transferase activityGO:00513383550.027
cytoplasmic transportGO:00164823790.027
nucleotide catabolic processGO:00091664080.027
female gamete generationGO:000729220.027
canonical wnt signaling pathwayGO:00600701160.026
oogenesisGO:004847720.026
chromatin modificationGO:00165682980.026
actin filament based movementGO:0030048170.026
response to oxygen containing compoundGO:19017003690.026
negative regulation of cell cycleGO:00457861930.026
negative regulation of apoptotic processGO:00430663160.026
cell projection organizationGO:00300302520.026
guanosine containing compound catabolic processGO:19010692390.026
neural tube formationGO:000184130.026
regulation of protein localizationGO:00328802960.025
compound eye developmentGO:004874910.025
regulation of protein transportGO:00512232130.025
neuromuscular junction developmentGO:000752830.024
positive regulation of programmed cell deathGO:00430682490.024
cell adhesionGO:00071553250.024
signal transduction by phosphorylationGO:00230142970.024
regulation of nucleotide catabolic processGO:00308112050.024
negative regulation of programmed cell deathGO:00430693210.024
positive regulation of cell deathGO:00109422630.024
regulation of protein kinase activityGO:00458592890.024
ribonucleotide catabolic processGO:00092614050.024
mesenchymal cell developmentGO:0014031500.024
positive regulation of apoptotic processGO:00430652460.024
negative regulation of cellular protein metabolic processGO:00322693530.024
gtp catabolic processGO:00061842370.024
regulation of nucleotide metabolic processGO:00061402690.023
membrane organizationGO:00610242920.023
nucleoside catabolic processGO:00091644080.023
organ formationGO:004864530.023
nucleoside triphosphate metabolic processGO:00091414220.023
negative regulation of catalytic activityGO:00430863350.023
stem cell developmentGO:0048864690.023
cellular response to oxygen containing compoundGO:19017012760.023
transmembrane transportGO:00550853990.023
negative regulation of protein metabolic processGO:00512483910.023
purine nucleoside catabolic processGO:00061523980.023
cellular response to dna damage stimulusGO:00069743790.023
blastocyst developmentGO:000182430.023
mitotic cell cycleGO:00002783260.023
urogenital system developmentGO:0001655650.023
anion transportGO:00068201610.023
regulation of establishment of protein localizationGO:00702012420.023
circulatory system processGO:00030131130.023
positive regulation of cell proliferationGO:00082843010.023
chemical homeostasisGO:00488783060.022
wnt signaling pathwayGO:00160551560.022
growthGO:00400072020.022
regulation of cellular response to stressGO:00801352440.022
ameboidal type cell migrationGO:00016671350.021
regulation of intracellular transportGO:00323861950.021
single organism cellular localizationGO:19025803320.021
guanosine containing compound metabolic processGO:19010682440.021
organ morphogenesisGO:00098871470.021
epithelial cell proliferationGO:00506731280.021
positive regulation of purine nucleotide metabolic processGO:19005442270.021
locomotory behaviorGO:000762610.021
posttranscriptional regulation of gene expressionGO:00106082130.021
organelle assemblyGO:00709251760.021
mapk cascadeGO:00001652880.021
single organism membrane organizationGO:00448022680.021
positive regulation of cellular catabolic processGO:00313312840.021
dephosphorylationGO:00163112090.020
chromatin organizationGO:00063253510.020
positive regulation of protein phosphorylationGO:00019343130.020
regulation of hormone levelsGO:00108171250.020
response to abiotic stimulusGO:00096283360.020
positive regulation of cellular amine metabolic processGO:003324070.020
positive regulation of cellular component organizationGO:00511303760.020
negative regulation of phosphate metabolic processGO:00459362670.020
protein localization to organelleGO:00333652800.020
positive regulation of cell differentiationGO:00455972110.020
cation homeostasisGO:00550801890.020
positive regulation of cellular amino acid metabolic processGO:004576430.020
regulation of kinase activityGO:00435493140.020
gtp metabolic processGO:00460392390.019
regulation of nucleoside metabolic processGO:00091182090.019
cellular ion homeostasisGO:00068731680.019
cell projection assemblyGO:00300311260.019
regulation of purine nucleotide metabolic processGO:19005422640.019
cell growthGO:00160491600.019
catagenGO:004263730.019
oocyte developmentGO:004859910.019
primary neural tube formationGO:001402030.019
blood vessel morphogenesisGO:00485141620.019
tissue morphogenesisGO:0048729960.019
photoreceptor cell differentiationGO:004653020.019
regulation of mitotic cell cycleGO:00073461890.019
regulation of dna metabolic processGO:00510521530.019
nervous system developmentGO:00073992930.019
Zebrafish
regulation of cell adhesionGO:00301551660.019
negative regulation of phosphorus metabolic processGO:00105632670.019
negative regulation of cellular amino acid metabolic processGO:004576320.019
negative regulation of epidermal cell differentiationGO:004560540.019
cellular macromolecule catabolic processGO:00442653800.019
protein maturationGO:00516042330.018
anterior posterior axis specificationGO:000994820.018
regulation of cell morphogenesisGO:00226041530.018
positive regulation of keratinocyte proliferationGO:001083840.018
regulation of cell cycle processGO:00105642660.018
secretionGO:00469032540.018
somatic stem cell maintenanceGO:003501940.018
regulation of gtpase activityGO:00430871800.018
defense responseGO:00069523150.018
cell morphogenesis involved in differentiationGO:00009041440.018
regulation of proteolysisGO:00301622930.018
neurogenesisGO:00220081690.018
regenerationGO:003109940.018
negative regulation of cellular amine metabolic processGO:003323930.017
regulation of peptidase activityGO:00525471800.017
mitotic cell cycle processGO:19030472860.017
prostate gland developmentGO:003085030.017
blood vessel developmentGO:00015681720.017
oocyte differentiationGO:000999420.017
regulation of cytoplasmic transportGO:19036491490.017
positive regulation of protein kinase activityGO:00458601900.017
regulation of cell growthGO:00015581350.017
prostate gland morphogenesisGO:006051210.017
regulation of growthGO:00400081650.017
positive regulation of nucleotide catabolic processGO:00308131850.017
negative regulation of wnt signaling pathwayGO:0030178690.017
epithelial tube branching involved in lung morphogenesisGO:006044140.017
tissue homeostasisGO:0001894630.017
tube developmentGO:00352951250.017
Zebrafish
cell divisionGO:00513011680.017
response to organic cyclic compoundGO:00140702040.017
regulation of sequence specific dna binding transcription factor activityGO:00510902110.017
negative regulation of cell cycle processGO:00109481210.017
inner ear morphogenesisGO:004247240.017
positive regulation of purine nucleotide catabolic processGO:00331231850.017
blastoderm segmentationGO:000735020.017
renal system developmentGO:0072001630.017
secretion by cellGO:00329402260.016
regulation of ras protein signal transductionGO:00465781550.016
immune responseGO:00069553070.016
endocytosisGO:00068971590.016
protein catabolic processGO:00301633250.016
positive regulation of developmental processGO:00510943140.016
cellular macromolecular complex assemblyGO:00346223240.016
positive regulation of nucleotide metabolic processGO:00459812300.016
regulation of endopeptidase activityGO:00525481700.016
rna processingGO:00063962550.016
striated muscle contractionGO:0006941520.016
mesendoderm developmentGO:004838210.016
mesenchyme developmentGO:0060485590.016
tube morphogenesisGO:0035239950.016
regulation of system processGO:00440571010.016
epidermis morphogenesisGO:004873030.016
protein ubiquitinationGO:00165673140.016
histone modificationGO:00165702510.016
metal ion homeostasisGO:00550651690.016
microtubule based processGO:00070172100.016
positive regulation of protein transportGO:00512221350.016
regulation of multi organism processGO:00439001570.016
establishment of protein localization to membraneGO:00901501210.016
regulation of wnt signaling pathwayGO:00301111230.016
regulation of cell developmentGO:00602841610.016
peripheral nervous system developmentGO:000742220.015
epidermal cell differentiationGO:0009913450.015
salivary gland morphogenesisGO:000743540.015
negative regulation of keratinocyte differentiationGO:004561730.015
ectoderm developmentGO:000739830.015
negative regulation of intracellular signal transductionGO:19025321830.015
ion transmembrane transportGO:00342203380.015
negative regulation of hydrolase activityGO:00513461820.015
intracellular protein transportGO:00068862700.015
memoryGO:000761330.015
regulation of body fluid levelsGO:0050878990.015
positive regulation of nucleoside metabolic processGO:00459791860.015
cell junction organizationGO:0034330790.015
regulation of ras gtpase activityGO:00323181280.015
response to organonitrogen compoundGO:00102431560.015
cellular response to nitrogen compoundGO:19016991440.015
spermatid differentiationGO:004851540.015
ion homeostasisGO:00508012300.015
stem cell differentiationGO:0048863930.015
single organism cell adhesionGO:00986021790.015
regulation of meiotic cell cycleGO:005144540.014
cranial nerve developmentGO:002154540.014
reproductive processGO:00224141060.014
positive regulation of gtpase activityGO:00435471660.014
positive regulation of transferase activityGO:00513472270.014
morphogenesis of an epitheliumGO:0002009600.014
embryonic placenta developmentGO:000189210.014
regulation of cell morphogenesis involved in differentiationGO:0010769830.014
plasma membrane organizationGO:00070091150.014
organophosphate biosynthetic processGO:00904071630.014
single organism reproductive processGO:0044702980.014
cell fate determinationGO:000170930.014
muscle system processGO:0003012810.014
nuclear transportGO:00511691790.014
regulation of vesicle mediated transportGO:00606271300.014
negative regulation of cell growthGO:0030308830.014
negative regulation of growthGO:0045926970.014
multicellular organismal homeostasisGO:0048871670.014
morphogenesis of a polarized epitheliumGO:000173830.014
embryo developmentGO:00097901230.014
Zebrafish
reactive oxygen species biosynthetic processGO:190340940.014
angiogenesisGO:00015251470.014
keratinocyte proliferationGO:0043616170.014
mesenchymal cell differentiationGO:0048762520.014
protein localization to membraneGO:00726571600.014
regulation of intracellular protein transportGO:00331571230.014
regulation of purine nucleotide catabolic processGO:00331212050.014
nerve developmentGO:002167540.014
covalent chromatin modificationGO:00165692540.014
maintenance of locationGO:00512351120.014
multicellular organismal response to stressGO:003355510.014
protein targetingGO:00066051870.014
vasculature developmentGO:00019441810.014
inorganic ion transmembrane transportGO:00986602310.014
rna splicingGO:00083801310.014
tripartite regional subdivisionGO:000735120.014
regulation of cellular component biogenesisGO:00440872810.014
neuron fate commitmentGO:004866320.014
thymus developmentGO:004853830.013
neural crest cell migrationGO:000175520.013
organic hydroxy compound metabolic processGO:19016151470.013
cell cycle phase transitionGO:00447701730.013
embryonic morphogenesisGO:0048598850.013
Zebrafish
positive regulation of ras gtpase activityGO:00323201170.013
head developmentGO:00603221080.013
Zebrafish
protein localization to nucleusGO:00345041360.013
keratinizationGO:003142420.013
cdc42 protein signal transductionGO:003248840.013
cellular protein catabolic processGO:00442572610.013
positive regulation of cell migrationGO:00303351720.013
cellular lipid metabolic processGO:00442553030.013
hormone metabolic processGO:0042445610.013
regulation of protein maturationGO:19033171500.013
carbohydrate metabolic processGO:00059752070.013
cellular protein complex assemblyGO:00436231880.013
positive regulation of transportGO:00510503360.013
endosomal transportGO:00161971290.013
hindbrain developmentGO:003090230.013
heart contractionGO:0060047620.013
regulation of cysteine type endopeptidase activityGO:20001161270.013
cell cell junction organizationGO:0045216690.013
regulation of locomotionGO:00400123290.013
negative regulation of protein modification processGO:00314002000.013
blastocyst formationGO:000182530.013
negative regulation of organelle organizationGO:00106391260.013
cellular homeostasisGO:00197251960.013
positive regulation of sequence specific dna binding transcription factor activityGO:00510911310.013
neuron differentiationGO:00301821380.013
cation transportGO:00068123310.013
regulation of response to external stimulusGO:00321012220.013
somitogenesisGO:000175620.013
forebrain generation of neuronsGO:002187230.013
specification of organ identityGO:001009230.013
viral life cycleGO:00190581320.013
metal ion transportGO:00300012720.013
spermatid developmentGO:000728640.013
anterior posterior axis specification embryoGO:000859520.013
regulation of canonical wnt signaling pathwayGO:0060828880.013
regulation of cell projection organizationGO:00313441070.013
cell part morphogenesisGO:00329901370.013
cell cell signalingGO:00072671550.013
embryonic camera type eye developmentGO:003107620.013
protein processingGO:00164852260.013
oxidation reduction processGO:00551143960.013
positive regulation of mapk cascadeGO:00434101900.013
protein autophosphorylationGO:00467771230.012
cell projection morphogenesisGO:00488581290.012
generation of neuronsGO:00486991520.012
cation transmembrane transportGO:00986552380.012
regulation of rho protein signal transductionGO:0035023790.012
muscle contractionGO:0006936730.012
regulation of epidermis developmentGO:0045682190.012
epithelial to mesenchymal transitionGO:0001837480.012
regulation of small gtpase mediated signal transductionGO:00510561560.012
positive regulation of intracellular protein transportGO:0090316760.012
transmembrane receptor protein tyrosine kinase signaling pathwayGO:00071691810.012
cellular response to organonitrogen compoundGO:00714171240.012
lipid biosynthetic processGO:00086101770.012
endodermal cell fate commitmentGO:000171140.012
cellular component disassemblyGO:0022411920.012
second messenger mediated signalingGO:0019932780.012
regulation of cell cycle phase transitionGO:19019871260.012
regulation of cell migrationGO:00303342890.012
somatic muscle developmentGO:000752510.012
regulation of cysteine type endopeptidase activity involved in apoptotic processGO:00432811160.012
reactive oxygen species metabolic processGO:0072593750.012
lipid metabolic processGO:00066293810.012
tissue regenerationGO:004224630.012
positive regulation of insulin like growth factor receptor signaling pathwayGO:004356840.012
positive regulation of cellular component biogenesisGO:00440891580.012
positive regulation of kinase activityGO:00336742040.012
cell migration involved in gastrulationGO:004207410.012
response to fungusGO:000962040.012
establishment of protein localization to organelleGO:00725941720.012
regulation of cytokine productionGO:00018172320.012
cell substrate adhesionGO:00315891320.012
positive regulation of gtp catabolic processGO:00331261660.012
neuroblast proliferationGO:000740540.012
positive regulation of tooth mineralizationGO:007017220.012
epidermis developmentGO:0008544590.012
protein acylationGO:00435431380.012
inorganic cation transmembrane transportGO:00986621940.012
chemotaxisGO:00069351570.012
regulation of protein processingGO:00706131500.011
monovalent inorganic cation transportGO:00156721280.011
establishment of planar polarityGO:000173630.011
nitrogen compound transportGO:00717051910.011
stem cell divisionGO:001714520.011
melanin metabolic processGO:000658210.011
proteolysis involved in cellular protein catabolic processGO:00516032440.011
regulation of symbiosis encompassing mutualism through parasitismGO:00439031090.011
cilium morphogenesisGO:0060271750.011
regulation of cardiac muscle contractionGO:0055117330.011
gastrulation with mouth forming secondGO:000170210.011
negative regulation of canonical wnt signaling pathwayGO:0090090550.011
cellular response to organic cyclic compoundGO:00714071270.011
regulation of mapk cascadeGO:00434082620.011
negative regulation of mitotic cell cycleGO:00459301020.011
post embryonic organ developmentGO:004856910.011
cuticle developmentGO:004233510.011
regulation of epithelial to mesenchymal transitionGO:0010717370.011
tissue migrationGO:00901301190.011
blood circulationGO:00080151130.011
negative regulation of phosphorylationGO:00423261740.011
regulation of gtp catabolic processGO:00331241800.011
positive regulation of cell cycleGO:00457871400.011
regulation of protein serine threonine kinase activityGO:00719001790.011
negative regulation of protein phosphorylationGO:00019331400.011
response to salt stressGO:000965130.011
innate immune responseGO:00450871780.011
response to cytokineGO:00340972320.011
t cell differentiation in thymusGO:003307740.011
rhythmic behaviorGO:000762220.011
mammary gland morphogenesisGO:006044320.011
cellular cation homeostasisGO:00300031630.011
trabecula morphogenesisGO:006138320.011
negative regulation of gliogenesisGO:001401430.011
negative regulation of stem cell differentiationGO:2000737220.011
neural tube closureGO:000184330.011
organic anion transportGO:00157111030.011
establishment or maintenance of bipolar cell polarityGO:006124520.011
ossificationGO:00015031210.011
negative regulation of cellular component movementGO:00512711060.011
modification dependent protein catabolic processGO:00199412090.011
cell fate commitment involved in pattern specificationGO:006058110.011
cilium organizationGO:0044782680.011
dna repairGO:00062811980.011
apoptotic signaling pathwayGO:00971902680.011
regulation of catagenGO:005179430.011
peptidyl lysine modificationGO:00182051440.011
negative regulation of transferase activityGO:00513481240.011
epithelial cell developmentGO:0002064340.011
hair follicle morphogenesisGO:003106920.011
adult locomotory behaviorGO:000834410.011
regulation of cell divisionGO:00513021160.010
cilium assemblyGO:0042384630.010
atp metabolic processGO:00460341760.010
regulation of protein stabilityGO:0031647870.010
neuron projection developmentGO:00311751060.010
neurological system processGO:00508771630.010
regulation of reactive oxygen species biosynthetic processGO:190342630.010
regulation of cell motilityGO:20001452990.010
cartilage condensationGO:000150210.010
endodermal cell fate specificationGO:000171440.010
regulation of neural precursor cell proliferationGO:200017740.010
response to nitrogen compoundGO:19016981840.010
tube closureGO:006060630.010
positive regulation of organelle organizationGO:00106381950.010
negative regulation of kinase activityGO:00336731060.010
modification dependent macromolecule catabolic processGO:00436322120.010
cellular response to cytokine stimulusGO:00713451810.010
notch signaling pathwayGO:0007219310.010
embryonic camera type eye morphogenesisGO:004859620.010
negative regulation of protein maturationGO:19033181420.010
regulation of viral processGO:00507921030.010
retinal ganglion cell axon guidanceGO:003129020.010
positive regulation of epithelial cell proliferationGO:0050679650.010
carbohydrate derivative biosynthetic processGO:19011372070.010
positive regulation of dna metabolic processGO:0051054730.010
positive regulation of proteolysisGO:00458621420.010
intracellular receptor signaling pathwayGO:00305221040.010
response to growth factorGO:00708482050.010
positive regulation of aldosterone biosynthetic processGO:003234920.010
sequestering of metal ionGO:0051238240.010
limbic system developmentGO:002176130.010
positive regulation of aldosterone metabolic processGO:003234620.010
single organismal cell cell adhesionGO:00163371480.010
nucleus localizationGO:005164710.010
forebrain neuron differentiationGO:002187930.010
action potentialGO:0001508340.010
negative regulation of protein kinase activityGO:0006469980.010
ubiquitin dependent protein catabolic processGO:00065112060.010

GRHL2 disease predictions

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of metabolismDOID:00146672950.024
nervous system diseaseDOID:8634310.023
sensory system diseaseDOID:00501552030.023
disease of cellular proliferationDOID:145661740.019
organ system cancerDOID:00506861640.019
cancerDOID:1621670.019
musculoskeletal system diseaseDOID:172230.016
central nervous system diseaseDOID:3311860.015
inherited metabolic disorderDOID:6552420.014
eye and adnexa diseaseDOID:14921500.012
connective tissue diseaseDOID:651090.012
bone diseaseDOID:0080001880.012
eye diseaseDOID:56141490.012
auditory system diseaseDOID:2742530.010
nonsyndromic deafnessDOID:0050563500.007
autosomal dominant nonsyndromic deafnessDOID:0050564230.005