Homo sapiens

61 known processes

HOGA1

4-hydroxy-2-oxoglutarate aldolase 1

(Aliases: NPL2,HP3,DHDPSL,FLJ37472,C10orf65,DHDPS2,FLJ56960)

HOGA1 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
cellular amino acid metabolic processGO:00065201160.104
cellular ketone metabolic processGO:0042180800.069
post embryonic developmentGO:000979120.066
cellular amine metabolic processGO:0044106410.064
lipid metabolic processGO:00066293810.063
amine metabolic processGO:0009308440.062
regulation of cellular amine metabolic processGO:0033238110.061
regulation of cellular amino acid metabolic processGO:000652160.059
transmembrane transportGO:00550853990.057
regulation of cellular ketone metabolic processGO:0010565500.056
positive regulation of cellular amino acid metabolic processGO:004576430.054
chemical homeostasisGO:00488783060.053
cation transmembrane transportGO:00986552380.051
positive regulation of cellular amine metabolic processGO:003324070.051
cellular lipid metabolic processGO:00442553030.050
cation transportGO:00068123310.047
system processGO:00030083490.042
multicellular organismal agingGO:001025930.040
ion transmembrane transportGO:00342203380.040
inorganic ion transmembrane transportGO:00986602310.039
metal ion transportGO:00300012720.039
purine ribonucleoside metabolic processGO:00461284370.039
ion homeostasisGO:00508012300.038
inorganic cation transmembrane transportGO:00986621940.038
positive regulation of transportGO:00510503360.038
positive regulation of phosphorylationGO:00423273940.038
small gtpase mediated signal transductionGO:0007264780.038
determination of adult lifespanGO:000834020.038
ras protein signal transductionGO:0007265730.036
locomotory behaviorGO:000762610.036
purine ribonucleoside triphosphate metabolic processGO:00092054110.035
purine containing compound catabolic processGO:00725234110.035
nucleoside catabolic processGO:00091644080.035
nucleoside triphosphate metabolic processGO:00091414220.035
regulation of cellular component movementGO:00512703340.035
ribonucleoside catabolic processGO:00424544060.035
female gamete generationGO:000729220.034
purine nucleoside triphosphate metabolic processGO:00091444120.034
monocarboxylic acid metabolic processGO:00327871850.034
nucleotide catabolic processGO:00091664080.033
response to oxygen containing compoundGO:19017003690.033
regulation of hormone levelsGO:00108171250.033
single organism cellular localizationGO:19025803320.033
anion transportGO:00068201610.033
membrane organizationGO:00610242920.032
nucleoside phosphate catabolic processGO:19012924120.032
positive regulation of catabolic processGO:00098963100.032
negative regulation of protein metabolic processGO:00512483910.032
ribonucleoside triphosphate metabolic processGO:00091994120.032
negative regulation of catalytic activityGO:00430863350.032
nucleoside triphosphate catabolic processGO:00091433940.032
small molecule biosynthetic processGO:00442831570.032
ribonucleotide catabolic processGO:00092614050.031
cellular chemical homeostasisGO:00550821800.031
response to abiotic stimulusGO:00096283360.031
purine nucleoside catabolic processGO:00061523980.031
biological adhesionGO:00226103310.031
glycosyl compound catabolic processGO:19016584130.031
organophosphate catabolic processGO:00464344300.031
ribonucleoside triphosphate catabolic processGO:00092033910.031
cell adhesionGO:00071553250.030
cellular response to endogenous stimulusGO:00714953360.030
negative regulation of cellular protein metabolic processGO:00322693530.029
purine nucleoside triphosphate catabolic processGO:00091463920.029
purine ribonucleotide catabolic processGO:00091544040.029
purine ribonucleoside catabolic processGO:00461303980.029
purine ribonucleoside triphosphate catabolic processGO:00092073910.029
positive regulation of hydrolase activityGO:00513453310.029
negative regulation of cell deathGO:00605483450.028
oogenesisGO:004847720.028
single organism membrane organizationGO:00448022680.028
secretionGO:00469032540.028
purine nucleotide catabolic processGO:00061954050.028
actin filament based processGO:00300292240.028
negative regulation of phosphate metabolic processGO:00459362670.028
cytoplasmic transportGO:00164823790.028
organic hydroxy compound metabolic processGO:19016151470.027
regulation of kinase activityGO:00435493140.027
positive regulation of cellular catabolic processGO:00313312840.027
regenerationGO:003109940.027
positive regulation of cellular component organizationGO:00511303760.027
regulation of transferase activityGO:00513383550.027
morphogenesis of embryonic epitheliumGO:001633140.027
cardiac muscle cell contractionGO:008600340.027
regulation of proteolysisGO:00301622930.027
negative regulation of phosphorus metabolic processGO:00105632670.027
regulation of cell cycleGO:00517263930.026
segmentationGO:003528240.025
positive regulation of protein phosphorylationGO:00019343130.025
protein localization to organelleGO:00333652800.025
anatomical structure formation involved in morphogenesisGO:00486462840.025
regulation of protein localizationGO:00328802960.025
nervous system developmentGO:00073992930.025
lipid biosynthetic processGO:00086101770.025
organonitrogen compound biosynthetic processGO:19015662000.025
positive regulation of transferase activityGO:00513472270.025
cellular macromolecule catabolic processGO:00442653800.025
cellular component morphogenesisGO:00329893140.025
regulation of purine nucleotide metabolic processGO:19005422640.025
nitrogen compound transportGO:00717051910.025
memoryGO:000761330.024
neuromuscular junction developmentGO:000752830.024
oxidation reduction processGO:00551143960.024
vesicle mediated transportGO:00161923710.024
gtp metabolic processGO:00460392390.024
regulation of protein kinase activityGO:00458592890.024
protein catabolic processGO:00301633250.024
mapk cascadeGO:00001652880.024
regulation of cell migrationGO:00303342890.024
regulation of nucleotide metabolic processGO:00061402690.024
negative regulation of programmed cell deathGO:00430693210.024
enzyme linked receptor protein signaling pathwayGO:00071673030.024
cell developmentGO:00484683280.023
cellular homeostasisGO:00197251960.023
protein maturationGO:00516042330.023
immune responseGO:00069553070.023
carbohydrate metabolic processGO:00059752070.023
carbohydrate derivative biosynthetic processGO:19011372070.023
apoptotic signaling pathwayGO:00971902680.023
negative regulation of apoptotic processGO:00430663160.023
regulation of nucleoside metabolic processGO:00091182090.023
negative regulation of transportGO:00510511760.023
response to organic cyclic compoundGO:00140702040.023
positive regulation of nucleotide metabolic processGO:00459812300.023
cellular cation homeostasisGO:00300031630.023
regulation of nucleotide catabolic processGO:00308112050.022
rho protein signal transductionGO:0007266260.022
metal ion homeostasisGO:00550651690.022
cardiovascular system developmentGO:00723582620.022
cellular response to dna damage stimulusGO:00069743790.022
positive regulation of purine nucleotide metabolic processGO:19005442270.022
response to nitrogen compoundGO:19016981840.022
alcohol metabolic processGO:00060661140.022
guanosine containing compound metabolic processGO:19010682440.022
mitotic cell cycleGO:00002783260.022
signal transduction by phosphorylationGO:00230142970.022
regulation of cellular response to stressGO:00801352440.022
guanosine containing compound catabolic processGO:19010692390.022
protein processingGO:00164852260.022
intracellular protein transportGO:00068862700.022
negative regulation of hydrolase activityGO:00513461820.022
cellular macromolecular complex assemblyGO:00346223240.021
negative regulation of cellular amino acid metabolic processGO:004576320.021
cellular ion homeostasisGO:00068731680.021
regulation of purine nucleotide catabolic processGO:00331212050.021
defense responseGO:00069523150.021
reactive oxygen species biosynthetic processGO:190340940.021
cell projection organizationGO:00300302520.021
cellular response to oxygen containing compoundGO:19017012760.021
regulation of cell differentiationGO:00455953930.021
circulatory system developmentGO:00723592620.021
regulation of locomotionGO:00400123290.020
regulation of gtp catabolic processGO:00331241800.020
cell morphogenesisGO:00009022960.020
inner ear morphogenesisGO:004247240.020
regulation of cellular component biogenesisGO:00440872810.020
dephosphorylationGO:00163112090.020
gtp catabolic processGO:00061842370.020
mitotic cell cycle processGO:19030472860.020
fatty acid metabolic processGO:00066311150.020
cation homeostasisGO:00550801890.020
carboxylic acid biosynthetic processGO:0046394970.020
endomembrane system organizationGO:00102561960.020
single organism carbohydrate metabolic processGO:00447231930.020
organophosphate biosynthetic processGO:00904071630.020
regulation of mapk cascadeGO:00434082620.020
organic acid biosynthetic processGO:0016053970.020
hindbrain developmentGO:003090230.019
small molecule catabolic processGO:0044282920.019
regulation of cell cycle processGO:00105642660.019
regulation of secretionGO:00510461940.019
negative regulation of protein modification processGO:00314002000.019
positive regulation of gtp catabolic processGO:00331261660.019
negative regulation of cellular component organizationGO:00511292350.019
cellular protein catabolic processGO:00442572610.019
regulation of gtpase activityGO:00430871800.019
negative regulation of cellular amine metabolic processGO:003323930.019
regulation of cell motilityGO:20001452990.019
regulation of ion transportGO:00432691890.019
g protein coupled receptor signaling pathwayGO:00071862070.019
positive regulation of kinase activityGO:00336742040.019
cellular metal ion homeostasisGO:00068751460.019
organic anion transportGO:00157111030.019
regulation of establishment of protein localizationGO:00702012420.019
regulation of synaptic plasticityGO:004816730.019
regulation of anatomical structure morphogenesisGO:00226032860.018
positive regulation of nucleoside metabolic processGO:00459791860.018
adult locomotory behaviorGO:000834410.018
regulation of secretion by cellGO:19035301770.018
protein ubiquitinationGO:00165673140.018
secretion by cellGO:00329402260.018
protein modification by small protein conjugationGO:00324463420.018
positive regulation of mapk cascadeGO:00434101900.018
positive regulation of gtpase activityGO:00435471660.018
maintenance of locationGO:00512351120.018
blastoderm segmentationGO:000735020.018
regulation of transmembrane transportGO:00347621390.018
cell fate determinationGO:000170930.018
regulation of peptidase activityGO:00525471800.018
divalent inorganic cation homeostasisGO:00725071360.018
regulation of protein transportGO:00512232130.018
regulation of cytokine productionGO:00018172320.018
positive regulation of purine nucleotide catabolic processGO:00331231850.018
positive regulation of synaptic transmissionGO:005080640.018
organ formationGO:004864530.018
protein localization to membraneGO:00726571600.017
positive regulation of cell deathGO:00109422630.017
positive regulation of cellular component movementGO:00512721810.017
peripheral nervous system developmentGO:000742220.017
embryonic epithelial tube formationGO:000183840.017
muscle contractionGO:0006936730.017
negative regulation of intracellular signal transductionGO:19025321830.017
reactive nitrogen species metabolic processGO:200105730.017
positive regulation of programmed cell deathGO:00430682490.017
positive regulation of protein kinase activityGO:00458601900.017
positive regulation of immune system processGO:00026842830.017
positive regulation of developmental processGO:00510943140.017
regulation of response to external stimulusGO:00321012220.017
rhythmic behaviorGO:000762220.017
positive regulation of cell migrationGO:00303351720.017
divalent inorganic cation transportGO:00725111580.017
positive regulation of cell proliferationGO:00082843010.017
oocyte developmentGO:004859910.017
positive regulation of nucleotide catabolic processGO:00308131850.017
growthGO:00400072020.017
negative regulation of transcription from rna polymerase ii promoterGO:00001222810.017
monovalent inorganic cation transportGO:00156721280.017
spermatid differentiationGO:004851540.017
negative regulation of cell cycleGO:00457861930.017
negative regulation of cell proliferationGO:00082852280.017
regulation of protein processingGO:00706131500.017
muscle system processGO:0003012810.017
regulation of apoptotic signaling pathwayGO:20012331750.017
regulation of reactive oxygen species biosynthetic processGO:190342630.017
cytokine productionGO:00018162470.017
sulfur compound metabolic processGO:00067901010.017
response to hormoneGO:00097251750.016
negative regulation of protein processingGO:00109551420.016
generation of neuronsGO:00486991520.016
regulation of neural precursor cell proliferationGO:200017740.016
positive regulation of secretionGO:00510471160.016
wnt signaling pathwayGO:00160551560.016
oocyte differentiationGO:000999420.016
calcium ion homeostasisGO:00550741220.016
proteolysis involved in cellular protein catabolic processGO:00516032440.016
positive regulation of apoptotic processGO:00430652460.016
protein oligomerizationGO:00512591730.016
cell growthGO:00160491600.016
protein targetingGO:00066051870.016
negative regulation of multicellular organismal processGO:00512413170.016
anterior posterior axis specificationGO:000994820.016
regulation of endopeptidase activityGO:00525481700.016
response to external biotic stimulusGO:00432072610.016
response to fungusGO:000962040.016
regulation of ion transmembrane transportGO:00347651320.016
response to organonitrogen compoundGO:00102431560.016
striated muscle contractionGO:0006941520.016
cellular protein complex assemblyGO:00436231880.016
regulation of small gtpase mediated signal transductionGO:00510561560.016
negative regulation of protein maturationGO:19033181420.016
cellular calcium ion homeostasisGO:00068741170.016
neurogenesisGO:00220081690.016
innate immune responseGO:00450871780.015
response to lipidGO:00339932060.015
regulation of growthGO:00400081650.015
regulation of protein maturationGO:19033171500.015
response to woundingGO:00096111680.015
cellular response to hormone stimulusGO:00328701250.015
circadian behaviorGO:004851220.015
cellular response to nitrogen compoundGO:19016991440.015
reactive oxygen species metabolic processGO:0072593750.015
actin cytoskeleton organizationGO:00300362070.015
associative learningGO:000830610.015
compound eye developmentGO:004874910.015
organelle assemblyGO:00709251760.015
cell cycle phase transitionGO:00447701730.015
response to inorganic substanceGO:00100351270.015
divalent metal ion transportGO:00708381520.015
response to biotic stimulusGO:00096072760.015
calcium ion transportGO:00068161470.015
response to cytokineGO:00340972320.015
actin filament based movementGO:0030048170.015
regulation of intracellular transportGO:00323861950.015
neuroblast proliferationGO:000740540.015
proteasomal protein catabolic processGO:00104981760.015
response to growth factorGO:00708482050.015
regulation of mitotic cell cycleGO:00073461890.015
plasma membrane organizationGO:00070091150.015
regulation of cell growthGO:00015581350.015
negative regulation of phosphorylationGO:00423261740.015
actin mediated cell contractionGO:0070252120.015
sequestering of metal ionGO:0051238240.015
regulation of ras gtpase activityGO:00323181280.015
positive regulation of cell differentiationGO:00455972110.015
regulation of protein serine threonine kinase activityGO:00719001790.014
cellular response to growth factor stimulusGO:00713631970.014
anterior posterior axis specification embryoGO:000859520.014
cellular divalent inorganic cation homeostasisGO:00725031280.014
regulation of cytoskeleton organizationGO:00514931770.014
establishment of protein localization to membraneGO:00901501210.014
regulation of cell developmentGO:00602841610.014
epithelium developmentGO:00604292270.014
regulation of homeostatic processGO:00328441210.014
microtubule based processGO:00070172100.014
spermatid developmentGO:000728640.014
response to other organismGO:00517072610.014
tissue regenerationGO:004224630.014
cell projection assemblyGO:00300311260.014
photoreceptor cell differentiationGO:004653020.014
posttranscriptional regulation of gene expressionGO:00106082130.014
modification dependent macromolecule catabolic processGO:00436322120.014
tripartite regional subdivisionGO:000735120.014
positive regulation of ras gtpase activityGO:00323201170.014
positive regulation of cell motilityGO:20001471770.014
positive regulation of reactive oxygen species biosynthetic processGO:190342820.014
multicellular organismal response to stressGO:003355510.014
regulation of cell adhesionGO:00301551660.014
mitochondrion organizationGO:00070051560.014
regulation of cell morphogenesisGO:00226041530.014
establishment of protein localization to organelleGO:00725941720.014
visual behaviorGO:000763220.014
negative regulation of proteolysisGO:00458611320.014
neuron differentiationGO:00301821380.014
purine ribonucleoside monophosphate metabolic processGO:00091671860.014
modification dependent protein catabolic processGO:00199412090.014
regulation of reactive oxygen species metabolic processGO:2000377410.014
purine nucleoside monophosphate metabolic processGO:00091261860.014
mitotic cell cycle phase transitionGO:00447721620.014
cardiac muscle contractionGO:0060048340.014
phospholipid metabolic processGO:0006644990.014
response to axon injuryGO:004867810.014
circulatory system processGO:00030131130.014
single organism cell adhesionGO:00986021790.013
response to radiationGO:00093141510.013
proteasome mediated ubiquitin dependent protein catabolic processGO:00431611560.013
anion transmembrane transportGO:0098656760.013
regulation of ras protein signal transductionGO:00465781550.013
salivary gland morphogenesisGO:000743540.013
motor neuron axon guidanceGO:000804520.013
positive regulation of organelle organizationGO:00106381950.013
positive regulation of cellular component biogenesisGO:00440891580.013
rna processingGO:00063962550.013
regulation of actin filament based processGO:00329701410.013
cell substrate adhesionGO:00315891320.013
regulation of transporter activityGO:0032409820.013
cellular response to cytokine stimulusGO:00713451810.013
regulation of protein catabolic processGO:00421761550.013
regulation of sequence specific dna binding transcription factor activityGO:00510902110.013
positive regulation of secretion by cellGO:19035321080.013
regulation of dna metabolic processGO:00510521530.013
ribonucleoside monophosphate metabolic processGO:00091611870.013
cell cell signalingGO:00072671550.013
nucleocytoplasmic transportGO:00069131760.013
ubiquitin dependent protein catabolic processGO:00065112060.013
angiogenesisGO:00015251470.013
establishment or maintenance of bipolar cell polarityGO:006124520.013
cellular modified amino acid metabolic processGO:0006575640.013
alpha amino acid metabolic processGO:1901605720.013
nuclear transportGO:00511691790.013
cell part morphogenesisGO:00329901370.013
regulation of membrane potentialGO:0042391950.013
nucleotide biosynthetic processGO:00091651090.013
lipid transportGO:0006869900.013
atp metabolic processGO:00460341760.013
limbic system developmentGO:002176130.013
carboxylic acid catabolic processGO:0046395710.013
cofactor metabolic processGO:0051186870.013
neurotransmitter secretionGO:000726940.013
metencephalon developmentGO:002203720.013
regulation of wnt signaling pathwayGO:00301111230.013
peptidyl tyrosine phosphorylationGO:00181081700.013
nucleoside monophosphate metabolic processGO:00091231910.012
chromatin organizationGO:00063253510.012
negative regulation of protein phosphorylationGO:00019331400.012
cell divisionGO:00513011680.012
symbiosis encompassing mutualism through parasitismGO:00444031560.012
positive regulation of locomotionGO:00400171860.012
long term memoryGO:000761620.012
cell projection morphogenesisGO:00488581290.012
response to drugGO:0042493810.012
startle responseGO:000196430.012
regulation of multi organism processGO:00439001570.012
neural tube formationGO:000184130.012
transmembrane receptor protein tyrosine kinase signaling pathwayGO:00071691810.012
pituitary gland developmentGO:002198320.012
histone modificationGO:00165702510.012
glycerolipid metabolic processGO:00464861070.012
regulation of metal ion transportGO:00109591200.012
sequestering of calcium ionGO:0051208170.012
regulation of meiotic cell cycleGO:005144540.012
viral processGO:00160321460.012
organic hydroxy compound biosynthetic processGO:1901617710.012
dna repairGO:00062811980.012
multi organism cellular processGO:00447641560.012
negative regulation of organelle organizationGO:00106391260.012
interspecies interaction between organismsGO:00444191560.012
positive regulation of protein transportGO:00512221350.012
negative regulation of developmental processGO:00510932470.012
syncytium formation by plasma membrane fusionGO:000076820.012
axis elongationGO:000340140.012
sensory perception of painGO:001923340.012
response to oxygen levelsGO:00704821000.012
positive regulation of reactive oxygen species metabolic processGO:2000379240.012
protein localization to plasma membraneGO:0072659930.012
regulation of transmembrane transporter activityGO:0022898740.012
sodium ion transmembrane transportGO:0035725590.012
spinal cord developmentGO:002151040.012
protein homooligomerizationGO:00512601000.012
regulation of vasculature developmentGO:1901342970.012
positive regulation of ion transportGO:0043270870.012
blood vessel morphogenesisGO:00485141620.012
response to oxidative stressGO:00069791210.012
meiotic chromosome segregationGO:004513240.012
matingGO:000761810.012
extrinsic apoptotic signaling pathwayGO:00971911190.012
somitogenesisGO:000175620.012
negative regulation of transferase activityGO:00513481240.012
monocarboxylic acid biosynthetic processGO:0072330670.012
establishment or maintenance of apical basal cell polarityGO:003508820.012
sex determinationGO:000753030.012
cell morphogenesis involved in differentiationGO:00009041440.012
intrinsic apoptotic signaling pathwayGO:00971931270.012
regulation of response to woundingGO:19030341010.012
nerve developmentGO:002167540.012
central nervous system developmentGO:00074171230.011
positive regulation of cytokine productionGO:00018191670.011
peptidyl tyrosine modificationGO:00182121700.011
epithelial cell differentiationGO:00308551410.011
neurological system processGO:00508771630.011
positive regulation of proteolysisGO:00458621420.011
primary neural tube formationGO:001402030.011
positive regulation of neural precursor cell proliferationGO:200017920.011
regulation of cysteine type endopeptidase activity involved in apoptotic processGO:00432811160.011
purine containing compound biosynthetic processGO:0072522880.011
negative regulation of growthGO:0045926970.011
chromatin modificationGO:00165682980.011
tube closureGO:006060630.011
positive regulation of gliogenesisGO:001401540.011
blood vessel developmentGO:00015681720.011
glycerophospholipid metabolic processGO:0006650840.011
response to decreased oxygen levelsGO:0036293960.011
potassium ion transportGO:0006813620.011
negative regulation of catabolic processGO:00098951040.011
rna interferenceGO:001624640.011
organic acid transportGO:0015849650.011
response to metal ionGO:0010038840.011
protein acylationGO:00435431380.011
cellular response to lipidGO:00713961270.011
visual learningGO:000854210.011
defense response to fungusGO:005083240.011
organ morphogenesisGO:00098871470.011
negative regulation of apoptotic signaling pathwayGO:2001234970.011
response to hypoxiaGO:0001666960.011
coenzyme metabolic processGO:0006732650.011
thymus developmentGO:004853830.011
regulation of cytoplasmic transportGO:19036491490.011
covalent chromatin modificationGO:00165692540.011
glycoprotein metabolic processGO:00091001100.011
vasculature developmentGO:00019441810.011
regulation of ion transmembrane transporter activityGO:0032412720.011
hormone transportGO:0009914680.011
sensory perception of smellGO:000760820.011
establishment of planar polarityGO:000173630.011
cellular response to abiotic stimulusGO:00712141170.011
neuron developmentGO:00486661130.011
regulation of i kappab kinase nf kappab signalingGO:00431221620.011
endocytosisGO:00068971590.011
endosomal transportGO:00161971290.011
steroid metabolic processGO:0008202940.011
astrocyte differentiationGO:004870840.011
regulation of immune responseGO:00507762010.011
behaviorGO:00076101120.011

HOGA1 disease predictions

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of metabolismDOID:00146672950.044
inherited metabolic disorderDOID:6552420.031
nervous system diseaseDOID:8634310.028
sensory system diseaseDOID:00501552030.028
musculoskeletal system diseaseDOID:172230.021
disease of cellular proliferationDOID:145661740.019
cancerDOID:1621670.019
eye diseaseDOID:56141490.019
eye and adnexa diseaseDOID:14921500.019
organ system cancerDOID:00506861640.018
retinal diseaseDOID:56791180.016
cardiovascular system diseaseDOID:12871060.016
central nervous system diseaseDOID:3311860.016
connective tissue diseaseDOID:651090.013
bone diseaseDOID:0080001880.012
amino acid metabolic disorderDOID:9252500.012
retinal degenerationDOID:8466890.012
neurodegenerative diseaseDOID:12891020.011
muscular diseaseDOID:00800001140.011
muscle tissue diseaseDOID:661130.011
immune system diseaseDOID:29141550.011