Homo sapiens

128 known processes

STK11

serine/threonine kinase 11

(Aliases: LKB1,PJS)

STK11 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
asymmetric stem cell divisionGO:009872211.000
Worm Fly
asymmetric neuroblast divisionGO:005505911.000
Worm Fly
neuroblast divisionGO:005505711.000
Worm Fly
neuronal stem cell divisionGO:003644511.000
Worm Fly
stem cell divisionGO:001714521.000
Worm Fly
peptidyl threonine phosphorylationGO:0018107410.997
Worm
peptidyl threonine modificationGO:0018210450.996
Worm
positive regulation of cellular amine metabolic processGO:003324070.995
somatic stem cell divisionGO:004810310.993
Worm Fly
regulation of cellular ketone metabolic processGO:0010565500.991
protein localization to synapseGO:003541820.990
activation of protein kinase activityGO:0032147900.987
positive regulation of cellular amino acid metabolic processGO:004576430.981
post embryonic developmentGO:000979120.978
Worm
cellular amino acid metabolic processGO:00065201160.977
neuroblast proliferationGO:000740540.961
Worm Fly
regulation of cellular amine metabolic processGO:0033238110.958
regulation of transferase activityGO:00513383550.920
positive regulation of phosphorylationGO:00423273940.918
positive regulation of transferase activityGO:00513472270.907
positive regulation of protein serine threonine kinase activityGO:00719021190.906
regulation of protein serine threonine kinase activityGO:00719001790.902
positive regulation of protein kinase activityGO:00458601900.891
positive regulation of protein phosphorylationGO:00019343130.888
cellular ketone metabolic processGO:0042180800.854
nuclear exportGO:0051168690.839
cell fate commitmentGO:0045165270.835
Worm Fly
regulation of kinase activityGO:00435493140.803
regulation of cellular amino acid metabolic processGO:000652160.788
positive regulation of peptidyl threonine phosphorylationGO:001080090.778
positive regulation of kinase activityGO:00336742040.769
protein export from nucleusGO:0006611290.728
intracellular protein transportGO:00068862700.694
cell divisionGO:00513011680.636
Worm Fly
regulation of protein kinase activityGO:00458592890.591
embryo developmentGO:00097901230.525
Fly
amine metabolic processGO:0009308440.515
nervous system developmentGO:00073992930.497
Mouse Worm Fly
peptidyl serine phosphorylationGO:00181051010.483
nuclear transportGO:00511691790.477
establishment or maintenance of cell polarityGO:0007163310.451
Mouse Worm Fly
cell fate determinationGO:000170930.420
Worm
nucleocytoplasmic transportGO:00069131760.393
neurogenesisGO:00220081690.386
Mouse Worm Fly
protein heterooligomerizationGO:0051291160.341
generation of neuronsGO:00486991520.301
Mouse Worm Fly
regulation of peptidyl threonine phosphorylationGO:0010799150.295
protein oligomerizationGO:00512591730.282
cellular amine metabolic processGO:0044106410.281
apoptotic signaling pathwayGO:00971902680.276
cytoplasmic transportGO:00164823790.271
negative regulation of cell proliferationGO:00082852280.244
cellular component morphogenesisGO:00329893140.238
Mouse
embryo development ending in birth or egg hatchingGO:0009792340.221
Fly
positive regulation of developmental processGO:00510943140.215
Mouse Worm
extrinsic apoptotic signaling pathwayGO:00971911190.212
stem cell proliferationGO:0072089250.193
Worm Fly
positive regulation of cellular catabolic processGO:00313312840.174
stress activated protein kinase signaling cascadeGO:0031098940.172
Fly
establishment or maintenance of epithelial cell apical basal polarityGO:004519710.171
peptidyl serine modificationGO:00182091060.169
tube developmentGO:00352951250.166
Zebrafish
negative regulation of extrinsic apoptotic signaling pathwayGO:2001237520.166
regulation of extrinsic apoptotic signaling pathway in absence of ligandGO:2001239200.146
negative regulation of programmed cell deathGO:00430693210.145
neural precursor cell proliferationGO:006135160.145
Worm Fly
response to oxygen containing compoundGO:19017003690.140
positive regulation of catabolic processGO:00098963100.136
growthGO:00400072020.126
Mouse
protein autophosphorylationGO:00467771230.116
negative regulation of apoptotic signaling pathwayGO:2001234970.115
negative regulation of extrinsic apoptotic signaling pathway in absence of ligandGO:2001240160.111
chromatin organizationGO:00063253510.091
cellular response to interleukin 1GO:0071347350.088
cytokine mediated signaling pathwayGO:00192211090.086
establishment or maintenance of bipolar cell polarityGO:006124520.085
small gtpase mediated signal transductionGO:0007264780.083
regulation of cell cycleGO:00517263930.082
protein ubiquitinationGO:00165673140.080
establishment or maintenance of apical basal cell polarityGO:003508820.079
synapse organizationGO:0050808140.076
negative regulation of apoptotic processGO:00430663160.075
negative regulation of cell deathGO:00605483450.074
positive regulation of cell proliferationGO:00082843010.073
cell projection organizationGO:00300302520.070
Mouse
cellular response to cytokine stimulusGO:00713451810.068
chromatin assembly or disassemblyGO:0006333780.067
protein catabolic processGO:00301633250.066
regulation of small gtpase mediated signal transductionGO:00510561560.066
reactive nitrogen species metabolic processGO:200105730.065
digestive tract developmentGO:0048565750.064
Zebrafish
chromatin modificationGO:00165682980.064
negative regulation of cellular protein metabolic processGO:00322693530.062
purine nucleoside catabolic processGO:00061523980.061
negative regulation of protein phosphorylationGO:00019331400.061
regulation of growthGO:00400081650.059
Mouse
protein stabilizationGO:0050821640.057
cell morphogenesisGO:00009022960.055
Mouse
positive regulation of cellular component organizationGO:00511303760.055
Mouse
response to abiotic stimulusGO:00096283360.054
Mouse
cell type specific apoptotic processGO:00972851250.053
regulation of cellular response to stressGO:00801352440.052
Fly
negative regulation of phosphate metabolic processGO:00459362670.051
regulation of cell cycle processGO:00105642660.050
Worm
lipid biosynthetic processGO:00086101770.048
immune system developmentGO:00025201950.048
Mouse
response to nitrogen compoundGO:19016981840.048
stress activated mapk cascadeGO:0051403930.048
Fly
regulation of extrinsic apoptotic signaling pathwayGO:2001236850.047
signal transduction by phosphorylationGO:00230142970.047
Fly
cellular response to endogenous stimulusGO:00714953360.047
purine nucleoside triphosphate catabolic processGO:00091463920.046
cellular response to external stimulusGO:00714961110.045
covalent chromatin modificationGO:00165692540.044
cellular macromolecule catabolic processGO:00442653800.043
determination of adult lifespanGO:000834020.042
Worm Fly
anatomical structure formation involved in morphogenesisGO:00486462840.042
peptidyl tyrosine modificationGO:00182121700.041
Mouse
leukocyte activationGO:00453211640.041
Mouse
response to oxidative stressGO:00069791210.041
Worm
positive regulation of cell projection organizationGO:0031346640.041
Mouse
response to lipidGO:00339932060.041
mitotic cell cycleGO:00002783260.041
Fly
cardiovascular system developmentGO:00723582620.041
Mouse
neural tube formationGO:000184130.040
neuron differentiationGO:00301821380.039
Mouse
regulation of cell morphogenesisGO:00226041530.039
Mouse
cell part morphogenesisGO:00329901370.039
Mouse
blastoderm segmentationGO:000735020.039
Fly
modification dependent macromolecule catabolic processGO:00436322120.037
actin cytoskeleton organizationGO:00300362070.037
cellular response to oxygen containing compoundGO:19017012760.036
cell projection morphogenesisGO:00488581290.036
Mouse
epithelium developmentGO:00604292270.036
Zebrafish Fly
regulation of anatomical structure morphogenesisGO:00226032860.035
Mouse
response to organic cyclic compoundGO:00140702040.035
regulation of wnt signaling pathwayGO:00301111230.034
Mouse
histone modificationGO:00165702510.034
purine ribonucleoside triphosphate metabolic processGO:00092054110.033
neuromuscular junction developmentGO:000752830.033
cellular protein catabolic processGO:00442572610.033
negative regulation of catalytic activityGO:00430863350.033
purine ribonucleoside catabolic processGO:00461303980.033
negative regulation of transcription from rna polymerase ii promoterGO:00001222810.032
lymphocyte activationGO:00466491330.031
Mouse
regulation of nervous system developmentGO:0051960880.030
Mouse
positive regulation of cell differentiationGO:00455972110.030
Mouse
organophosphate catabolic processGO:00464344300.030
microtubule cytoskeleton organizationGO:00002261760.030
Fly
embryonic epithelial tube formationGO:000183840.029
ras protein signal transductionGO:0007265730.029
regulation of lymphocyte activationGO:00512491030.029
cellular response to oxidative stressGO:0034599850.028
regulation of protein catabolic processGO:00421761550.028
actin filament based processGO:00300292240.028
regulation of cell activationGO:00508651250.028
regulation of autophagyGO:0010506520.028
response to molecule of bacterial originGO:0002237820.028
proteolysis involved in cellular protein catabolic processGO:00516032440.028
positive regulation of purine nucleotide metabolic processGO:19005442270.028
purine nucleoside triphosphate metabolic processGO:00091444120.027
regulation of cellular protein catabolic processGO:1903362960.027
membrane organizationGO:00610242920.027
peptidyl tyrosine phosphorylationGO:00181081700.026
Mouse
endosomal transportGO:00161971290.026
cellular response to nutrient levelsGO:0031669690.026
proteasomal protein catabolic processGO:00104981760.026
negative regulation of intracellular signal transductionGO:19025321830.026
cell cycle arrestGO:0007050710.025
ribonucleoside catabolic processGO:00424544060.025
cytokine productionGO:00018162470.025
purine ribonucleotide catabolic processGO:00091544040.025
positive regulation of purine nucleotide catabolic processGO:00331231850.025
nucleoside catabolic processGO:00091644080.024
purine nucleotide catabolic processGO:00061954050.024
signal transduction in absence of ligandGO:0038034220.024
tube morphogenesisGO:0035239950.024
tissue morphogenesisGO:0048729960.024
Fly
response to other organismGO:00517072610.024
regulation of locomotionGO:00400123290.024
Worm
positive regulation of hydrolase activityGO:00513453310.024
modification dependent protein catabolic processGO:00199412090.023
positive regulation of gtp catabolic processGO:00331261660.023
vesicle mediated transportGO:00161923710.023
response to inorganic substanceGO:00100351270.023
multicellular organismal agingGO:001025930.023
Worm Fly
positive regulation of cell developmentGO:0010720920.023
Mouse
response to extracellular stimulusGO:0009991850.023
regulation of cellular component biogenesisGO:00440872810.023
neuron projection developmentGO:00311751060.022
Mouse
response to organonitrogen compoundGO:00102431560.022
response to nutrient levelsGO:0031667810.022
negative regulation of protein metabolic processGO:00512483910.022
autophagyGO:0006914880.022
negative regulation of phosphorus metabolic processGO:00105632670.022
regulation of response to dna damage stimulusGO:2001020940.022
system processGO:00030083490.022
negative regulation of cell cycleGO:00457861930.022
regulation of cell growthGO:00015581350.021
Mouse
regulation of reactive oxygen species biosynthetic processGO:190342630.021
secretionGO:00469032540.021
extrinsic apoptotic signaling pathway in absence of ligandGO:0097192220.021
organic hydroxy compound metabolic processGO:19016151470.021
regulation of cellular component movementGO:00512703340.021
response to external biotic stimulusGO:00432072610.021
toll like receptor 2 signaling pathwayGO:003413440.021
tissue migrationGO:00901301190.021
nucleoside phosphate catabolic processGO:19012924120.020
positive regulation of b cell activationGO:0050871170.020
lipid metabolic processGO:00066293810.020
nucleotide catabolic processGO:00091664080.020
positive regulation of nucleotide catabolic processGO:00308131850.020
negative regulation of protein modification processGO:00314002000.020
toll like receptor 3 signaling pathwayGO:003413840.020
immune response activating signal transductionGO:0002757900.020
Mouse
ribonucleoside monophosphate metabolic processGO:00091611870.020
regulation of proteasomal protein catabolic processGO:0061136870.019
hindbrain developmentGO:003090230.019
protein deubiquitinationGO:0016579790.019
regulation of ras protein signal transductionGO:00465781550.019
segmentationGO:003528240.019
Fly
regulation of nucleoside metabolic processGO:00091182090.019
positive regulation of immune system processGO:00026842830.019
Mouse
regulation of protein ubiquitinationGO:0031396950.019
purine containing compound catabolic processGO:00725234110.019
monocarboxylic acid metabolic processGO:00327871850.019
female gamete generationGO:000729220.019
Fly
positive regulation of neuron projection developmentGO:0010976340.019
Mouse
cell morphogenesis involved in differentiationGO:00009041440.019
Mouse
cell adhesionGO:00071553250.018
Fly
response to oxygen levelsGO:00704821000.018
positive regulation of programmed cell deathGO:00430682490.018
Fly
developmental process involved in reproductionGO:0003006660.018
Mouse Fly
negative regulation of protein kinase activityGO:0006469980.018
regulation of neuron projection developmentGO:0010975570.018
Mouse
microtubule based processGO:00070172100.018
Fly
negative regulation of signal transduction in absence of ligandGO:1901099160.017
biological adhesionGO:00226103310.017
Fly
cellular response to extracellular stimulusGO:0031668720.017
response to woundingGO:00096111680.017
rho protein signal transductionGO:0007266260.017
positive regulation of apoptotic processGO:00430652460.017
Fly
regulation of purine nucleotide catabolic processGO:00331212050.017
positive regulation of mapk cascadeGO:00434101900.017
embryonic camera type eye formationGO:006090020.017
regulation of response to external stimulusGO:00321012220.017
regulation of mapk cascadeGO:00434082620.017
Fly
anterior posterior axis specificationGO:000994820.017
Fly
ion homeostasisGO:00508012300.017
hemopoiesisGO:00300971800.017
Mouse
cell developmentGO:00484683280.017
Mouse Fly
regulation of map kinase activityGO:00434051080.016
ubiquitin dependent protein catabolic processGO:00065112060.016
glycosyl compound catabolic processGO:19016584130.016
response to hypoxiaGO:0001666960.016
negative regulation of phosphorylationGO:00423261740.016
cell cycle phase transitionGO:00447701730.016
blastocyst developmentGO:000182430.016
regenerationGO:003109940.016
innate immune responseGO:00450871780.016
protein modification by small protein conjugationGO:00324463420.016
muscle structure developmentGO:0061061980.016
positive regulation of cell deathGO:00109422630.016
Fly
regulation of protein modification by small protein conjugation or removalGO:19033201070.015
morphogenesis of embryonic epitheliumGO:001633140.015
Fly
lymphocyte homeostasisGO:000226040.015
purine ribonucleoside metabolic processGO:00461284370.015
ribonucleoside triphosphate catabolic processGO:00092033910.015
epithelial cell migrationGO:00106311190.015
hematopoietic or lymphoid organ developmentGO:00485341860.015
Mouse
negative regulation of cellular component organizationGO:00511292350.015
organ morphogenesisGO:00098871470.015
regulation of cell divisionGO:00513021160.015
Worm
blood vessel developmentGO:00015681720.015
regulation of protein stabilityGO:0031647870.015
neuron projection morphogenesisGO:0048812500.015
Mouse
steroid metabolic processGO:0008202940.015
mrna metabolic processGO:00160711750.015
cellular response to dna damage stimulusGO:00069743790.015
regulation of immune responseGO:00507762010.015
Mouse
negative regulation of cellular amino acid metabolic processGO:004576320.015
reactive oxygen species biosynthetic processGO:190340940.015
regulation of mitotic cell cycleGO:00073461890.015
i kappab kinase nf kappab signalingGO:00072491660.015
positive regulation of i kappab kinase nf kappab signalingGO:00431231320.015
mapk cascadeGO:00001652880.015
Fly
sex differentiationGO:0007548450.015
cellular lipid metabolic processGO:00442553030.015
positive regulation of immune responseGO:00507781590.014
Mouse
circulatory system developmentGO:00723592620.014
Mouse
chemotaxisGO:00069351570.014
positive regulation of protein catabolic processGO:0045732750.014
gtp catabolic processGO:00061842370.014
regulation of cell developmentGO:00602841610.014
Mouse
cellular response to lipidGO:00713961270.014
posttranscriptional regulation of gene expressionGO:00106082130.014
negative regulation of kinase activityGO:00336731060.014
positive regulation of locomotionGO:00400171860.014
Worm
spermatid differentiationGO:004851540.014
Mouse
negative regulation of lipid metabolic processGO:0045833380.014
purine ribonucleoside triphosphate catabolic processGO:00092073910.014
negative regulation of cellular catabolic processGO:0031330830.013
rna processingGO:00063962550.013
neurological system processGO:00508771630.013
response to decreased oxygen levelsGO:0036293960.013
reproductive processGO:00224141060.013
Mouse Fly
negative regulation of catabolic processGO:00098951040.013
positive regulation of nucleotide metabolic processGO:00459812300.013
embryonic placenta developmentGO:000189210.013
protein modification by small protein removalGO:0070646920.013
positive regulation of leukocyte activationGO:0002696800.013
positive regulation of cell motilityGO:20001471770.013
embryonic organ developmentGO:0048568360.013
regulation of cell migrationGO:00303342890.013
regulation of cyclin dependent protein serine threonine kinase activityGO:0000079360.013
nucleoside triphosphate metabolic processGO:00091414220.013
nuclear divisionGO:00002801280.013
guanosine containing compound metabolic processGO:19010682440.013
signal releaseGO:0023061700.013
neuroendocrine cell differentiationGO:006110120.013
neural tube closureGO:000184330.013
regulation of i kappab kinase nf kappab signalingGO:00431221620.013
steroid biosynthetic processGO:0006694460.012
nucleosome organizationGO:0034728660.012
regulation of proteolysis involved in cellular protein catabolic processGO:1903050910.012
regulation of hormone levelsGO:00108171250.012
positive regulation of map kinase activityGO:0043406800.012
negative regulation of protein serine threonine kinase activityGO:0071901570.012
regulation of synaptic plasticityGO:004816730.012
reproductive system developmentGO:0061458560.012
Mouse
regulation of sequence specific dna binding transcription factor activityGO:00510902110.012
positive regulation of transportGO:00510503360.012
immune responseGO:00069553070.012
Mouse
regulation of gene expression epigeneticGO:0040029730.012
peptidyl lysine modificationGO:00182051440.012
epithelium migrationGO:00901321190.012
epithelial cell proliferationGO:00506731280.012
Mouse
anoikisGO:0043276220.012
associative learningGO:000830610.012
cell morphogenesis involved in neuron differentiationGO:0048667440.012
Mouse
tube closureGO:006060630.012
peptidyl lysine acetylationGO:00183941010.012
syncytium formation by plasma membrane fusionGO:000076820.012
response to hormoneGO:00097251750.012
intracellular receptor signaling pathwayGO:00305221040.012
multi organism cellular processGO:00447641560.012
protein maturationGO:00516042330.012
behaviorGO:00076101120.012
regulation of neuron differentiationGO:0045664700.012
Mouse
positive regulation of anoikisGO:200021040.012
blood vessel morphogenesisGO:00485141620.012
organelle fissionGO:00482851490.012
response to hyperoxiaGO:005509340.012
regulation of b cell activationGO:0050864240.012
carbohydrate derivative biosynthetic processGO:19011372070.012
regulation of defense responseGO:00313471540.012
endothelial cell apoptotic processGO:0072577260.011
response to lipopolysaccharideGO:0032496700.011
oocyte developmentGO:004859910.011
Fly
dna repairGO:00062811980.011
single organism cellular localizationGO:19025803320.011
Fly
response to cytokineGO:00340972320.011
response to interleukin 1GO:0070555470.011
receptor mediated endocytosisGO:0006898840.011
gonad developmentGO:0008406340.011
locomotory behaviorGO:000762610.011
meiotic chromosome segregationGO:004513240.011
lens development in camera type eyeGO:000208820.011
regulation of tumor necrosis factor superfamily cytokine productionGO:1903555440.011
protein localization to membraneGO:00726571600.011
regulation of endopeptidase activityGO:00525481700.011
muscle tissue developmentGO:0060537620.011
bmp signaling pathwayGO:0030509490.011
embryonic hindlimb morphogenesisGO:003511620.011
cellular component disassemblyGO:0022411920.011
reproductive structure developmentGO:0048608550.011
Mouse
ribonucleoside triphosphate metabolic processGO:00091994120.011
mitotic nuclear divisionGO:00070671190.011
regulation of bindingGO:00510981110.011
response to starvationGO:0042594590.011
negative regulation of cellular amine metabolic processGO:003323930.011
erk1 and erk2 cascadeGO:00703711040.011
epidermis developmentGO:0008544590.011
plasma membrane organizationGO:00070091150.011
positive regulation of cell cycleGO:00457871400.011
regulation of type i interferon mediated signaling pathwayGO:006033890.011
symbiosis encompassing mutualism through parasitismGO:00444031560.011
maintenance of locationGO:00512351120.011
pharyngeal system developmentGO:006003720.011
positive regulation of wnt signaling pathwayGO:0030177540.011
positive regulation of neuron differentiationGO:0045666400.010
Mouse
cellular response to hydrogen peroxideGO:0070301370.010
secretion by cellGO:00329402260.010
single organism membrane organizationGO:00448022680.010
regulation of actin cytoskeleton organizationGO:00329561160.010
axon developmentGO:0061564340.010
Mouse
enzyme linked receptor protein signaling pathwayGO:00071673030.010
positive regulation of cell activationGO:0050867810.010
neural tube patterningGO:002153220.010
negative regulation of organelle organizationGO:00106391260.010
spermatid developmentGO:000728640.010
Mouse
regulation of cell motilityGO:20001452990.010
regulation of mitosisGO:0007088630.010
atp metabolic processGO:00460341760.010
protein acetylationGO:00064731160.010
chordate embryonic developmentGO:0043009340.010
response to radiationGO:00093141510.010
Mouse
regulation of tumor necrosis factor productionGO:0032680430.010
atp catabolic processGO:00062001570.010
cell cycle checkpointGO:00000751170.010
chromatin mediated maintenance of transcriptionGO:004809620.010
endocytosisGO:00068971590.010

STK11 disease predictions

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of cellular proliferationDOID:145661740.067
cancerDOID:1621670.067
organ system cancerDOID:00506861640.049
musculoskeletal system diseaseDOID:172230.024
nervous system diseaseDOID:8634310.014
central nervous system diseaseDOID:3311860.014
connective tissue diseaseDOID:651090.012
muscle tissue diseaseDOID:661130.012
muscular diseaseDOID:00800001140.012
integumentary system diseaseDOID:16430.012
skin diseaseDOID:37330.012
bone diseaseDOID:0080001880.011
endocrine gland cancerDOID:170260.006
male reproductive organ cancerDOID:3856160.002
reproductive organ cancerDOID:193230.002
gastrointestinal system diseaseDOID:77360.002
intestinal diseaseDOID:5295140.001
cell type cancerDOID:0050687100.001
pancreatic cancerDOID:179380.001
germ cell cancerDOID:299440.000
seminomaDOID:444030.000
testicular cancerDOID:299830.000
testicular germ cell cancerDOID:555730.000
pancreatic carcinomaDOID:490540.000