Homo sapiens

33 known processes

WIPI2

WD repeat domain, phosphoinositide interacting 2

(Aliases: WIPI-2,FLJ14217,Atg21,FLJ12979,DKFZp686P02188,FLJ42984,ATG18B,DKFZp434J154)

WIPI2 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
purine nucleotide catabolic processGO:00061954050.057
positive regulation of cellular amino acid metabolic processGO:004576430.055
cellular macromolecule catabolic processGO:00442653800.054
negative regulation of cell proliferationGO:00082852280.050
regulation of proteolysisGO:00301622930.048
purine ribonucleoside catabolic processGO:00461303980.048
purine ribonucleoside metabolic processGO:00461284370.047
cellular protein catabolic processGO:00442572610.045
amine metabolic processGO:0009308440.043
cellular response to dna damage stimulusGO:00069743790.042
protein localization to organelleGO:00333652800.042
Yeast
protein catabolic processGO:00301633250.042
organophosphate catabolic processGO:00464344300.042
regulation of cellular amino acid metabolic processGO:000652160.041
small molecule biosynthetic processGO:00442831570.040
cytoplasmic transportGO:00164823790.040
Human Yeast
regulation of cell cycleGO:00517263930.040
mapk cascadeGO:00001652880.040
nucleoside triphosphate metabolic processGO:00091414220.039
oogenesisGO:004847720.038
purine ribonucleotide catabolic processGO:00091544040.038
positive regulation of cellular amine metabolic processGO:003324070.038
ubiquitin dependent protein catabolic processGO:00065112060.038
modification dependent macromolecule catabolic processGO:00436322120.037
cellular amine metabolic processGO:0044106410.037
regulation of cellular amine metabolic processGO:0033238110.036
signal transduction by phosphorylationGO:00230142970.035
lipid metabolic processGO:00066293810.035
mitotic cell cycleGO:00002783260.035
purine nucleoside triphosphate metabolic processGO:00091444120.035
ribonucleoside triphosphate metabolic processGO:00091994120.035
purine nucleoside triphosphate catabolic processGO:00091463920.034
regulation of cellular response to stressGO:00801352440.034
ribonucleotide catabolic processGO:00092614050.033
small gtpase mediated signal transductionGO:0007264780.033
modification dependent protein catabolic processGO:00199412090.033
cellular lipid metabolic processGO:00442553030.032
glycosyl compound catabolic processGO:19016584130.032
posttranscriptional regulation of gene expressionGO:00106082130.032
cellular ketone metabolic processGO:0042180800.031
cellular amino acid metabolic processGO:00065201160.031
positive regulation of catabolic processGO:00098963100.031
negative regulation of catalytic activityGO:00430863350.031
response to abiotic stimulusGO:00096283360.031
regulation of cellular ketone metabolic processGO:0010565500.030
protein ubiquitinationGO:00165673140.030
female gamete generationGO:000729220.030
purine ribonucleoside triphosphate metabolic processGO:00092054110.030
ribonucleoside catabolic processGO:00424544060.030
positive regulation of nucleotide metabolic processGO:00459812300.029
purine containing compound catabolic processGO:00725234110.029
negative regulation of apoptotic processGO:00430663160.029
positive regulation of hydrolase activityGO:00513453310.028
negative regulation of programmed cell deathGO:00430693210.028
vesicle mediated transportGO:00161923710.028
Human
regulation of nucleoside metabolic processGO:00091182090.028
cell differentiation in spinal cordGO:002151510.028
regulation of mapk cascadeGO:00434082620.027
regulation of kinase activityGO:00435493140.027
protein modification by small protein removalGO:0070646920.027
nucleotide catabolic processGO:00091664080.027
protein maturationGO:00516042330.027
regulation of cell cycle processGO:00105642660.027
purine nucleoside catabolic processGO:00061523980.027
nucleoside monophosphate metabolic processGO:00091231910.026
post embryonic developmentGO:000979120.026
Fly
regulation of cellular component movementGO:00512703340.026
proteolysis involved in cellular protein catabolic processGO:00516032440.026
mitotic cell cycle processGO:19030472860.026
ribonucleoside triphosphate catabolic processGO:00092033910.026
regulation of protein serine threonine kinase activityGO:00719001790.026
ras protein signal transductionGO:0007265730.025
regulation of nucleotide metabolic processGO:00061402690.025
determination of adult lifespanGO:000834020.025
multicellular organismal agingGO:001025930.025
rho protein signal transductionGO:0007266260.025
purine nucleoside monophosphate metabolic processGO:00091261860.025
apoptotic signaling pathwayGO:00971902680.025
ribonucleoside monophosphate metabolic processGO:00091611870.025
intracellular protein transportGO:00068862700.025
Yeast
gtp catabolic processGO:00061842370.024
segmentationGO:003528240.024
response to oxygen containing compoundGO:19017003690.024
nucleoside phosphate catabolic processGO:19012924120.024
regulation of protein kinase activityGO:00458592890.024
guanosine containing compound metabolic processGO:19010682440.024
regulation of transferase activityGO:00513383550.024
positive regulation of nucleotide catabolic processGO:00308131850.024
purine ribonucleoside triphosphate catabolic processGO:00092073910.024
proteasome mediated ubiquitin dependent protein catabolic processGO:00431611560.024
lung alveolus developmentGO:004828640.024
gtp metabolic processGO:00460392390.024
nucleoside catabolic processGO:00091644080.024
protein modification by small protein conjugationGO:00324463420.024
positive regulation of purine nucleotide metabolic processGO:19005442270.023
positive regulation of purine nucleotide catabolic processGO:00331231850.023
positive regulation of transportGO:00510503360.023
dephosphorylationGO:00163112090.023
negative regulation of protein metabolic processGO:00512483910.023
locomotory behaviorGO:000762610.023
negative regulation of cell cycleGO:00457861930.023
defense responseGO:00069523150.023
Fly
regulation of nucleotide catabolic processGO:00308112050.023
regulation of purine nucleotide metabolic processGO:19005422640.022
proteasomal protein catabolic processGO:00104981760.022
regulation of protein transportGO:00512232130.022
neuroblast proliferationGO:000740540.022
immune responseGO:00069553070.022
regulation of establishment of protein localizationGO:00702012420.022
membrane organizationGO:00610242920.021
Yeast
guanosine containing compound catabolic processGO:19010692390.021
negative regulation of cell cycle processGO:00109481210.021
transmembrane transportGO:00550853990.021
negative regulation of cellular protein metabolic processGO:00322693530.021
regulation of neural precursor cell proliferationGO:200017740.021
single organism cellular localizationGO:19025803320.021
Yeast
purine ribonucleoside monophosphate metabolic processGO:00091671860.021
carbohydrate metabolic processGO:00059752070.020
nucleus localizationGO:005164710.020
cell cycle phase transitionGO:00447701730.020
negative regulation of phosphorus metabolic processGO:00105632670.020
positive regulation of phosphorylationGO:00423273940.020
monocarboxylic acid metabolic processGO:00327871850.020
alcohol metabolic processGO:00060661140.020
sensory perception of painGO:001923340.020
positive regulation of cellular component organizationGO:00511303760.020
actin filament based processGO:00300292240.020
organic hydroxy compound metabolic processGO:19016151470.019
negative regulation of cellular component organizationGO:00511292350.019
positive regulation of apoptotic processGO:00430652460.019
cell cell signalingGO:00072671550.019
regulation of protein localizationGO:00328802960.019
cation transportGO:00068123310.019
cell cycle checkpointGO:00000751170.019
positive regulation of programmed cell deathGO:00430682490.019
positive regulation of cell deathGO:00109422630.019
spinal cord developmentGO:002151040.019
innate immune responseGO:00450871780.019
single organism membrane organizationGO:00448022680.019
Yeast
negative regulation of intracellular signal transductionGO:19025321830.019
Fly
system processGO:00030083490.018
lipid biosynthetic processGO:00086101770.018
maintenance of locationGO:00512351120.018
mitotic cell cycle phase transitionGO:00447721620.018
cell morphogenesisGO:00009022960.018
biological adhesionGO:00226103310.018
regulation of mitotic cell cycle phase transitionGO:19019901180.018
secretionGO:00469032540.018
neuromuscular junction developmentGO:000752830.018
atp metabolic processGO:00460341760.018
regulation of apoptotic signaling pathwayGO:20012331750.018
purine ribonucleoside monophosphate catabolic processGO:00091691580.018
positive regulation of cellular catabolic processGO:00313312840.018
secretion by cellGO:00329402260.018
regulation of protein catabolic processGO:00421761550.018
positive regulation of transferase activityGO:00513472270.018
organic acid biosynthetic processGO:0016053970.017
anterior posterior axis specificationGO:000994820.017
nucleoside monophosphate catabolic processGO:00091251590.017
regulation of cell motilityGO:20001452990.017
wnt signaling pathwayGO:00160551560.017
purine nucleoside monophosphate catabolic processGO:00091281580.017
cellular macromolecular complex assemblyGO:00346223240.017
autophagyGO:0006914880.017
cytokine productionGO:00018162470.017
regulation of secretionGO:00510461940.017
protein polyubiquitinationGO:00002091100.017
neurological system processGO:00508771630.016
nitrogen compound transportGO:00717051910.016
regulation of dephosphorylationGO:0035303960.016
regulation of secretion by cellGO:19035301770.016
compound eye developmentGO:004874910.016
regulation of cellular component biogenesisGO:00440872810.016
response to fungusGO:000962040.016
oocyte differentiationGO:000999420.016
regulation of cytokine productionGO:00018172320.016
memoryGO:000761330.016
hindbrain developmentGO:003090230.016
nervous system developmentGO:00073992930.016
single organism carbohydrate metabolic processGO:00447231930.016
positive regulation of synaptic transmissionGO:005080640.016
blastoderm segmentationGO:000735020.016
rhythmic behaviorGO:000762220.016
organelle localizationGO:0051640840.015
Human
cellular component morphogenesisGO:00329893140.015
regulation of anatomical structure morphogenesisGO:00226032860.015
negative regulation of protein processingGO:00109551420.015
regulation of intracellular transportGO:00323861950.015
carboxylic acid biosynthetic processGO:0046394970.015
cell adhesionGO:00071553250.015
reactive oxygen species biosynthetic processGO:190340940.015
regulation of growthGO:00400081650.015
negative regulation of hydrolase activityGO:00513461820.015
organophosphate biosynthetic processGO:00904071630.015
nucleocytoplasmic transportGO:00069131760.015
ventral spinal cord developmentGO:002151710.015
negative regulation of transportGO:00510511760.015
translationGO:00064121320.015
intrinsic apoptotic signaling pathwayGO:00971931270.015
response to cytokineGO:00340972320.015
regulation of purine nucleotide catabolic processGO:00331212050.015
protein processingGO:00164852260.015
oocyte developmentGO:004859910.014
negative regulation of phosphorylationGO:00423261740.014
associative learningGO:000830610.014
nucleoside triphosphate catabolic processGO:00091433940.014
endomembrane system organizationGO:00102561960.014
negative regulation of cell deathGO:00605483450.014
response to hormoneGO:00097251750.014
regulation of cytoplasmic transportGO:19036491490.014
dna damage checkpointGO:0000077680.014
response to other organismGO:00517072610.014
Fly
regulation of cell cycle phase transitionGO:19019871260.014
protein stabilizationGO:0050821640.014
positive regulation of secretionGO:00510471160.014
cell divisionGO:00513011680.014
negative regulation of cellular amine metabolic processGO:003323930.014
establishment of nucleus localizationGO:004002310.014
regulation of protein processingGO:00706131500.014
monovalent inorganic cation transportGO:00156721280.014
cellular response to oxygen containing compoundGO:19017012760.014
reactive oxygen species metabolic processGO:0072593750.014
chemical homeostasisGO:00488783060.014
inorganic ion transmembrane transportGO:00986602310.014
negative regulation of organelle organizationGO:00106391260.014
cell growthGO:00160491600.014
negative regulation of developmental processGO:00510932470.014
peripheral nervous system developmentGO:000742220.014
monocarboxylic acid biosynthetic processGO:0072330670.014
spermatid developmentGO:000728640.014
spermatid differentiationGO:004851540.014
ribonucleoside monophosphate catabolic processGO:00091581580.014
regulation of i kappab kinase nf kappab signalingGO:00431221620.014
response to growth factorGO:00708482050.014
circadian behaviorGO:004851220.014
regulation of intrinsic apoptotic signaling pathwayGO:2001242720.014
rna interferenceGO:001624640.014
reproductive processGO:00224141060.014
regulation of protein maturationGO:19033171500.013
regulation of locomotionGO:00400123290.013
positive regulation of kinase activityGO:00336742040.013
cellular response to endogenous stimulusGO:00714953360.013
endocytosisGO:00068971590.013
cell projection organizationGO:00300302520.013
cation homeostasisGO:00550801890.013
peptidyl serine phosphorylationGO:00181051010.013
metencephalon developmentGO:002203720.013
stress activated protein kinase signaling cascadeGO:0031098940.013
glycerolipid metabolic processGO:00464861070.013
protein importGO:00170381300.013
cytokinesisGO:0000910960.013
positive regulation of developmental processGO:00510943140.013
sleepGO:003043120.013
negative regulation of cellular amino acid metabolic processGO:004576320.013
adult locomotory behaviorGO:000834410.013
oxidation reduction processGO:00551143960.013
response to external biotic stimulusGO:00432072610.013
Fly
protein autophosphorylationGO:00467771230.013
establishment of protein localization to organelleGO:00725941720.013
Yeast
negative regulation of protein maturationGO:19033181420.013
regulation of reactive oxygen species biosynthetic processGO:190342630.013
phospholipid metabolic processGO:0006644990.013
ion transmembrane transportGO:00342203380.013
negative regulation of apoptotic signaling pathwayGO:2001234970.013
photoreceptor cell differentiationGO:004653020.013
regulation of intracellular protein transportGO:00331571230.013
positive regulation of protein kinase activityGO:00458601900.013
positive regulation of reactive oxygen species biosynthetic processGO:190342820.013
regulation of proteolysis involved in cellular protein catabolic processGO:1903050910.013
peptidyl tyrosine phosphorylationGO:00181081700.013
nuclear migrationGO:000709710.013
negative regulation of phosphate metabolic processGO:00459362670.013
jnk cascadeGO:0007254800.013
regulation of synaptic plasticityGO:004816730.013
negative regulation of mitotic cell cycle phase transitionGO:1901991850.013
negative regulation of multicellular organismal processGO:00512413170.013
rna processingGO:00063962550.012
regulation of cell growthGO:00015581350.012
regenerationGO:003109940.012
cardiovascular system developmentGO:00723582620.012
negative regulation of cell differentiationGO:00455961710.012
startle responseGO:000196430.012
positive regulation of gtp catabolic processGO:00331261660.012
cellular carbohydrate metabolic processGO:0044262840.012
negative regulation of cell cycle phase transitionGO:1901988890.012
regulation of cell migrationGO:00303342890.012
positive regulation of proteolysisGO:00458621420.012
negative regulation of growthGO:0045926970.012
negative regulation of protein modification processGO:00314002000.012
regulation of cell differentiationGO:00455953930.012
negative regulation of phosphatase activityGO:0010923610.012
protein oligomerizationGO:00512591730.012
glycerophospholipid metabolic processGO:0006650840.012
regulation of multi organism processGO:00439001570.012
Fly
regulation of ras gtpase activityGO:00323181280.012
positive regulation of protein phosphorylationGO:00019343130.012
positive regulation of mapk cascadeGO:00434101900.012
regulation of endopeptidase activityGO:00525481700.012
negative regulation of protein kinase activityGO:0006469980.012
response to nitrogen compoundGO:19016981840.012
positive regulation of nucleoside metabolic processGO:00459791860.012
i kappab kinase nf kappab signalingGO:00072491660.012
regulation of protein stabilityGO:0031647870.012
limbic system developmentGO:002176130.012
positive regulation of immune system processGO:00026842830.011
response to salt stressGO:000965130.011
stress activated mapk cascadeGO:0051403930.011
actin filament based movementGO:0030048170.011
regulation of small gtpase mediated signal transductionGO:00510561560.011
regulation of cellular protein catabolic processGO:1903362960.011
protein targetingGO:00066051870.011
Yeast
visual behaviorGO:000763220.011
regulation of translationGO:0006417890.011
negative regulation of cell growthGO:0030308830.011
negative regulation of proteolysisGO:00458611320.011
organonitrogen compound biosynthetic processGO:19015662000.011
protein localization to nucleusGO:00345041360.011
inner ear morphogenesisGO:004247240.011
symbiosis encompassing mutualism through parasitismGO:00444031560.011
positive regulation of cellular component biogenesisGO:00440891580.011
release of cytoplasmic sequestered nf kappabGO:000858840.011
regulation of reactive oxygen species metabolic processGO:2000377410.011
ion homeostasisGO:00508012300.011
positive regulation of gtpase activityGO:00435471660.011
regulation of ion transportGO:00432691890.011
response to organonitrogen compoundGO:00102431560.011
response to lipidGO:00339932060.011
stem cell differentiationGO:0048863930.011
syncytium formation by plasma membrane fusionGO:000076820.011
glial cell migrationGO:000834740.011
regulation of gtp catabolic processGO:00331241800.011
response to biotic stimulusGO:00096072760.011
Fly
tripartite regional subdivisionGO:000735120.011
response to bacteriumGO:00096171440.011
dna repairGO:00062811980.011
positive regulation of neural precursor cell proliferationGO:200017920.011
cellular metal ion homeostasisGO:00068751460.011
regulation of neurotransmitter secretionGO:004692830.011
positive regulation of organelle organizationGO:00106381950.011
cation transmembrane transportGO:00986552380.011
enzyme linked receptor protein signaling pathwayGO:00071673030.011
protein refoldingGO:0042026140.011
regulation of peptidase activityGO:00525471800.011
autophagic cell deathGO:004810230.011
organic hydroxy compound biosynthetic processGO:1901617710.011
cellular response to external stimulusGO:00714961110.011
endosomal transportGO:00161971290.011
Human
phosphatidylinositol metabolic processGO:0046488530.011
regulation of ras protein signal transductionGO:00465781550.011
regulation of proteasomal protein catabolic processGO:0061136870.010
microtubule cytoskeleton organizationGO:00002261760.010
motor neuron axon guidanceGO:000804520.010
metal ion homeostasisGO:00550651690.010
negative regulation of synaptic transmissionGO:005080520.010
embryo developmentGO:00097901230.010
actin filament organizationGO:00070151280.010
reactive nitrogen species metabolic processGO:200105730.010
negative regulation of transferase activityGO:00513481240.010
response to inorganic substanceGO:00100351270.010
positive regulation of protein transportGO:00512221350.010
chromosome segregationGO:00070591140.010
regulation of neuroblast proliferationGO:190269230.010
long term memoryGO:000761620.010
negative regulation of dephosphorylationGO:0035305630.010
growthGO:00400072020.010
somatic stem cell divisionGO:004810310.010
cardiac muscle cell contractionGO:008600340.010
cdc42 protein signal transductionGO:003248840.010

WIPI2 disease predictions

DiseaseDO term IDSizeProbabilityFunc Analog Org
musculoskeletal system diseaseDOID:172230.040
muscular diseaseDOID:00800001140.026
muscle tissue diseaseDOID:661130.026
myopathyDOID:4231040.026
nervous system diseaseDOID:8634310.024
central nervous system diseaseDOID:3311860.024
neurodegenerative diseaseDOID:12891020.016
cardiovascular system diseaseDOID:12871060.015
inherited metabolic disorderDOID:6552420.014
disease of metabolismDOID:00146672950.014
sensory system diseaseDOID:00501552030.014
muscular dystrophyDOID:9884510.014
disease of cellular proliferationDOID:145661740.013
eye and adnexa diseaseDOID:14921500.013
eye diseaseDOID:56141490.013
connective tissue diseaseDOID:651090.012
retinal diseaseDOID:56791180.011
heart diseaseDOID:114680.011
organ system cancerDOID:00506861640.011
cancerDOID:1621670.011
brain diseaseDOID:936730.010