Homo sapiens

16 known processes

ZNRF1

zinc and ring finger 1

(Aliases: DKFZp434E229,NIN283,MGC15430,FLJ14846)

ZNRF1 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
protein polyubiquitinationGO:00002091101.000
Mouse
protein modification by small protein conjugationGO:00324463421.000
protein ubiquitinationGO:00165673140.999
protein k48 linked ubiquitinationGO:0070936380.997
Mouse
protein autoubiquitinationGO:0051865370.989
protein k63 linked ubiquitinationGO:0070534310.979
ubiquitin dependent protein catabolic processGO:00065112060.974
Mouse
protein monoubiquitinationGO:0006513390.970
cellular protein catabolic processGO:00442572610.946
Mouse
modification dependent macromolecule catabolic processGO:00436322120.945
Mouse
modification dependent protein catabolic processGO:00199412090.935
Mouse
proteolysis involved in cellular protein catabolic processGO:00516032440.893
Mouse
histone ubiquitinationGO:0016574310.876
protein catabolic processGO:00301633250.692
Mouse
cellular macromolecule catabolic processGO:00442653800.624
Mouse
positive regulation of protein modification by small protein conjugation or removalGO:1903322610.503
histone monoubiquitinationGO:0010390200.333
protein k11 linked ubiquitinationGO:0070979240.302
positive regulation of response to dna damage stimulusGO:2001022430.293
protein ubiquitination involved in ubiquitin dependent protein catabolic processGO:0042787370.289
regulation of protein ubiquitinationGO:0031396950.278
viral release from host cellGO:0019076210.265
chromatin modificationGO:00165682980.258
regulation of i kappab kinase nf kappab signalingGO:00431221620.246
positive regulation of i kappab kinase nf kappab signalingGO:00431231320.239
cellular response to dna damage stimulusGO:00069743790.232
proteasomal protein catabolic processGO:00104981760.230
Mouse
positive regulation of protein polyubiquitinationGO:190291630.204
double strand break repairGO:00063021010.197
negative regulation of apoptotic processGO:00430663160.191
negative regulation of protein ubiquitination involved in ubiquitin dependent protein catabolic processGO:200005930.188
positive regulation of nf kappab transcription factor activityGO:0051092810.186
negative regulation of viral release from host cellGO:1902187120.184
regulation of interleukin 2 secretionGO:190004020.169
positive regulation of sequence specific dna binding transcription factor activityGO:00510911310.160
proteasome mediated ubiquitin dependent protein catabolic processGO:00431611560.157
Mouse
positive regulation of cellular component organizationGO:00511303760.154
chromatin organizationGO:00063253510.153
dna damage response detection of dna damageGO:004276930.144
regulation of response to dna damage stimulusGO:2001020940.142
dna repairGO:00062811980.136
regulation of viral release from host cellGO:1902186200.131
i kappab kinase nf kappab signalingGO:00072491660.129
locomotory behaviorGO:000762610.128
morphogenesis of embryonic epitheliumGO:001633140.123
entry into other organism involved in symbiotic interactionGO:0051828250.113
regulation of protein localizationGO:00328802960.110
regulation of dna repairGO:0006282470.106
positive regulation of cell cycleGO:00457871400.106
regulation of symbiosis encompassing mutualism through parasitismGO:00439031090.105
canonical wnt signaling pathwayGO:00600701160.094
regulation of cellular response to stressGO:00801352440.094
positive regulation of protein ubiquitinationGO:0031398530.094
ion transmembrane transportGO:00342203380.094
regulation of proteolysis involved in cellular protein catabolic processGO:1903050910.093
positive regulation of viral entry into host cellGO:004659830.093
regulation of protein polyubiquitinationGO:190291480.093
viral entry into host cellGO:0046718240.090
multi organism metabolic processGO:0044033410.089
regulation of viral transcriptionGO:0046782340.088
histone h2a ubiquitinationGO:0033522170.086
negative regulation of cell deathGO:00605483450.086
regulation of cell cycleGO:00517263930.086
immune response activating signal transductionGO:0002757900.085
entry into hostGO:0044409250.085
positive regulation of dna repairGO:0045739250.083
response to ionizing radiationGO:0010212650.079
positive regulation of phosphorylationGO:00423273940.078
cellular response to misfolded proteinGO:007121820.077
negative regulation of programmed cell deathGO:00430693210.077
movement in environment of other organism involved in symbiotic interactionGO:0052192250.074
covalent chromatin modificationGO:00165692540.073
regulation of endopeptidase activityGO:00525481700.072
regulation of proteolysisGO:00301622930.071
double strand break repair via homologous recombinationGO:0000724500.070
protein maturationGO:00516042330.070
actin cytoskeleton organizationGO:00300362070.069
negative regulation of viral processGO:0048525660.068
regulation of protein maturationGO:19033171500.068
negative regulation of developmental processGO:00510932470.067
interleukin 2 secretionGO:007097030.067
negative regulation of multi organism processGO:0043901920.065
viral gene expressionGO:0019080350.064
embryonic epithelial tube formationGO:000183840.058
negative regulation of transcription from rna polymerase ii promoterGO:00001222810.058
symbiosis encompassing mutualism through parasitismGO:00444031560.056
nervous system developmentGO:00073992930.056
post embryonic developmentGO:000979120.056
regulation of sequence specific dna binding transcription factor activityGO:00510902110.054
adult locomotory behaviorGO:000834410.052
viral life cycleGO:00190581320.052
neuromuscular junction developmentGO:000752830.050
multi organism cellular processGO:00447641560.049
signal transduction by phosphorylationGO:00230142970.048
cell developmentGO:00484683280.048
positive regulation of proteolysisGO:00458621420.048
protein processingGO:00164852260.048
regulation of protein modification by small protein conjugation or removalGO:19033201070.048
positive regulation of organelle organizationGO:00106381950.047
actin filament based processGO:00300292240.047
organelle assemblyGO:00709251760.047
positive regulation of catabolic processGO:00098963100.046
regulation of locomotionGO:00400123290.045
response to abiotic stimulusGO:00096283360.045
er associated ubiquitin dependent protein catabolic processGO:0030433310.044
regulation of protein processingGO:00706131500.044
regulation of transferase activityGO:00513383550.043
regulation of cell developmentGO:00602841610.043
cation transportGO:00068123310.043
mapk cascadeGO:00001652880.043
regulation of cell differentiationGO:00455953930.043
segmentationGO:003528240.043
wnt signaling pathwayGO:00160551560.042
negative regulation of cell cycle phase transitionGO:1901988890.042
regulation of viral processGO:00507921030.041
negative regulation of protein maturationGO:19033181420.041
activation of immune responseGO:00022531140.041
androgen receptor signaling pathwayGO:0030521340.040
regulation of chromosome organizationGO:00330441030.040
viral processGO:00160321460.039
negative regulation of protein metabolic processGO:00512483910.039
regulation of protein stabilityGO:0031647870.038
cellular protein complex assemblyGO:00436231880.038
histone modificationGO:00165702510.038
negative regulation of hydrolase activityGO:00513461820.038
posttranscriptional regulation of gene expressionGO:00106082130.038
defense responseGO:00069523150.038
positive regulation of cytokine productionGO:00018191670.037
photoreceptor cell differentiationGO:004653020.036
regulation of lipopolysaccharide mediated signaling pathwayGO:0031664130.036
mitotic cell cycleGO:00002783260.036
negative regulation of catalytic activityGO:00430863350.036
transmembrane transportGO:00550853990.036
positive regulation of dna metabolic processGO:0051054730.035
cellular macromolecular complex assemblyGO:00346223240.035
regulation of wnt signaling pathwayGO:00301111230.034
regulation of neuron differentiationGO:0045664700.034
entry into host cellGO:0030260250.034
interspecies interaction between organismsGO:00444191560.033
regulation of proteasomal ubiquitin dependent protein catabolic processGO:0032434710.033
positive regulation of mitotic cell cycleGO:0045931600.033
protein destabilizationGO:0031648120.033
nerve developmentGO:002167540.032
positive regulation of cellular catabolic processGO:00313312840.032
metal ion transportGO:00300012720.032
intracellular receptor signaling pathwayGO:00305221040.032
protein polymerizationGO:0051258710.031
negative regulation of peptidase activityGO:0010466910.031
growthGO:00400072020.031
regulation of transmembrane transportGO:00347621390.031
regulation of cell cycle processGO:00105642660.031
negative regulation of endopeptidase activityGO:0010951840.031
negative regulation of cell cycleGO:00457861930.030
regulation of glial cell proliferationGO:006025140.030
negative regulation of cell differentiationGO:00455961710.030
negative regulation of multicellular organismal processGO:00512413170.030
positive regulation of canonical wnt signaling pathwayGO:0090263330.030
regulation of mitotic cell cycleGO:00073461890.030
anatomical structure formation involved in morphogenesisGO:00486462840.030
negative regulation of proteolysisGO:00458611320.029
somitogenesisGO:000175620.029
intrinsic apoptotic signaling pathwayGO:00971931270.029
positive regulation of cellular component biogenesisGO:00440891580.029
response to oxidative stressGO:00069791210.029
positive regulation of actin filament polymerizationGO:0030838380.029
meiotic chromosome segregationGO:004513240.029
regulation of ion transmembrane transportGO:00347651320.029
regulation of actin polymerization or depolymerizationGO:0008064560.028
regulation of multi organism processGO:00439001570.028
negative regulation of cellular protein metabolic processGO:00322693530.027
regulation of dna metabolic processGO:00510521530.026
positive regulation of apoptotic signaling pathwayGO:2001235700.026
female gamete generationGO:000729220.026
positive regulation of immune system processGO:00026842830.026
regulation of cellular component biogenesisGO:00440872810.026
intracellular steroid hormone receptor signaling pathwayGO:0030518610.026
negative regulation of organelle organizationGO:00106391260.025
negative regulation of protein processingGO:00109551420.025
positive regulation of immune responseGO:00507781590.025
memoryGO:000761330.025
neural tube formationGO:000184130.025
cellular component morphogenesisGO:00329893140.025
neurogenesisGO:00220081690.025
regulation of protein transportGO:00512232130.025
positive regulation of proteasomal ubiquitin dependent protein catabolic processGO:0032436300.024
regulation of protein secretionGO:0050708860.024
positive regulation of protein linear polyubiquitinationGO:190253020.024
regulation of cytokine secretionGO:0050707570.023
dna recombinationGO:0006310770.023
regulation of nervous system developmentGO:0051960880.023
response to lipidGO:00339932060.023
system processGO:00030083490.023
regulation of mapk cascadeGO:00434082620.023
positive regulation of protein complex assemblyGO:0031334860.023
negative regulation of protein secretionGO:0050709290.023
cell morphogenesisGO:00009022960.022
regulation of cytoskeleton organizationGO:00514931770.022
response to oxygen containing compoundGO:19017003690.022
negative regulation of transferase activityGO:00513481240.022
regulation of organelle assemblyGO:1902115400.022
cell projection organizationGO:00300302520.022
positive regulation of cytoskeleton organizationGO:0051495830.022
regulation of secretionGO:00510461940.022
nucleic acid phosphodiester bond hydrolysisGO:00903051020.022
response to radiationGO:00093141510.022
regulation of cysteine type endopeptidase activityGO:20001161270.022
negative regulation of cell cycle processGO:00109481210.022
regulation of protein complex assemblyGO:00432541470.022
immune effector processGO:00022521590.022
positive regulation of transferase activityGO:00513472270.022
response to bacteriumGO:00096171440.021
reactive oxygen species metabolic processGO:0072593750.021
positive regulation of developmental processGO:00510943140.021
regulation of defense response to virusGO:0050688330.021
lipid localizationGO:00108761060.020
regulation of actin filament polymerizationGO:0030833500.020
actin nucleationGO:0045010210.020
protein localization to organelleGO:00333652800.020
negative regulation of locomotionGO:00400131180.020
regulation of neurogenesisGO:0050767820.020
negative regulation of transcription elongation from rna polymerase ii promoterGO:003424440.020
positive regulation of cellular amino acid metabolic processGO:004576430.019
regulation of metal ion transportGO:00109591200.019
postreplication repairGO:0006301120.019
cell projection morphogenesisGO:00488581290.019
regulation of protein catabolic processGO:00421761550.019
response to virusGO:00096151260.019
regulation of cell migrationGO:00303342890.019
dna catabolic processGO:0006308490.019
negative regulation of cysteine type endopeptidase activityGO:2000117480.019
regulation of stress activated mapk cascadeGO:0032872840.019
regulation of ubiquitin protein transferase activityGO:0051438280.018
negative regulation of apoptotic signaling pathwayGO:2001234970.018
regulation of cell motilityGO:20001452990.018
mitotic cell cycle phase transitionGO:00447721620.018
regulation of microtubule cytoskeleton organizationGO:0070507610.018
negative regulation of ion transportGO:0043271390.018
recombinational repairGO:0000725500.018
notch signaling pathwayGO:0007219310.018
negative regulation of phosphorylationGO:00423261740.018
positive regulation of cell deathGO:00109422630.018
vesicle mediated transportGO:00161923710.018
cellular response to lipidGO:00713961270.018
negative regulation of gliogenesisGO:001401430.018
histone h2a k63 linked ubiquitinationGO:007053550.018
regulation of calcium ion transportGO:0051924790.017
regulation of apoptotic signaling pathwayGO:20012331750.017
gastrulation with mouth forming secondGO:000170210.017
actin polymerization or depolymerizationGO:0008154560.017
blastoderm segmentationGO:000735020.017
mitotic cell cycle checkpointGO:0007093680.017
single organism membrane organizationGO:00448022680.017
actin filament organizationGO:00070151280.017
positive regulation of programmed cell deathGO:00430682490.017
microtubule organizing center organizationGO:0031023620.017
regulation of cellular protein catabolic processGO:1903362960.017
positive regulation of cellular protein catabolic processGO:1903364370.017
positive regulation of proteasomal protein catabolic processGO:1901800350.017
autophagic vacuole assemblyGO:0000045190.017
positive regulation of stress activated protein kinase signaling cascadeGO:0070304610.017
regulation of establishment of protein localizationGO:00702012420.016
neuron differentiationGO:00301821380.016
transmembrane receptor protein serine threonine kinase signaling pathwayGO:00071781250.016
detection of stimulusGO:0051606850.016
microtubule based processGO:00070172100.016
negative regulation of intracellular signal transductionGO:19025321830.016
cytokine productionGO:00018162470.016
immune response regulating signaling pathwayGO:0002764970.016
regulation of cysteine type endopeptidase activity involved in apoptotic processGO:00432811160.016
regulation of mitotic cell cycle phase transitionGO:19019901180.016
positive regulation of protein catabolic processGO:0045732750.016
regulation of intracellular steroid hormone receptor signaling pathwayGO:0033143320.016
oocyte differentiationGO:000999420.016
amine metabolic processGO:0009308440.016
cell cycle phase transitionGO:00447701730.016
regulation of kinase activityGO:00435493140.016
oogenesisGO:004847720.016
positive regulation of lipopolysaccharide mediated signaling pathwayGO:003166640.016
regulation of cell cycle phase transitionGO:19019871260.016
spinal cord developmentGO:002151040.016
protein k27 linked ubiquitinationGO:004431440.016
calcium ion transportGO:00068161470.016
positive regulation of locomotionGO:00400171860.016
negative regulation of glial cell proliferationGO:006025320.016
negative regulation of neurogenesisGO:0050768260.016
lipid metabolic processGO:00066293810.015
enzyme linked receptor protein signaling pathwayGO:00071673030.015
secretionGO:00469032540.015
ribonucleoside monophosphate metabolic processGO:00091611870.015
cellular amino acid metabolic processGO:00065201160.015
regulation of viral entry into host cellGO:0046596170.015
regulation of histone modificationGO:0031056470.015
negative regulation of transportGO:00510511760.015
regulation of anatomical structure sizeGO:00900661010.015
positive regulation of cellular component movementGO:00512721810.015
positive regulation of response to external stimulusGO:0032103880.015
positive regulation of rig i signaling pathwayGO:190024640.015
regulation of ion transportGO:00432691890.015
ras protein signal transductionGO:0007265730.015
generation of neuronsGO:00486991520.015
negative regulation of catabolic processGO:00098951040.015
neurological system processGO:00508771630.015
cellular response to starvationGO:0009267580.015
adaptive immune responseGO:0002250490.015
protein k29 linked ubiquitinationGO:003551940.015
viral transcriptionGO:0019083350.015
regulation of protein deubiquitinationGO:009008540.015
regulation of homeostatic processGO:00328441210.015
protein secretionGO:0009306980.015
anterior posterior axis specificationGO:000994820.015
negative regulation of cellular protein catabolic processGO:1903363380.015
chromosome segregationGO:00070591140.015
peripheral nervous system developmentGO:000742220.015
response to lipopolysaccharideGO:0032496700.014
regulation of intracellular transportGO:00323861950.014
motor neuron axon guidanceGO:000804520.014
ubiquitin dependent smad protein catabolic processGO:003057940.014
regulation of protein polymerizationGO:0032271630.014
regulation of response to external stimulusGO:00321012220.014
positive regulation of transportGO:00510503360.014
maintenance of locationGO:00512351120.014
innate immune responseGO:00450871780.014
cell growthGO:00160491600.014
interferon gamma productionGO:0032609390.014
negative regulation of protein deubiquitinationGO:009008630.014
positive regulation of multi organism processGO:0043902560.014
regulation of cytokine productionGO:00018172320.014
protein oligomerizationGO:00512591730.014
positive regulation of cell developmentGO:0010720920.014
regulation of protein ubiquitination involved in ubiquitin dependent protein catabolic processGO:200005870.014
regulation of intrinsic apoptotic signaling pathwayGO:2001242720.014
response to cytokineGO:00340972320.014
immune responseGO:00069553070.014
organ morphogenesisGO:00098871470.014
response to topologically incorrect proteinGO:0035966290.013
secretion by cellGO:00329402260.013
tripartite regional subdivisionGO:000735120.013
positive regulation of mapk cascadeGO:00434101900.013
notch receptor processingGO:000722020.013
negative regulation of wnt signaling pathwayGO:0030178690.013
regulation of canonical wnt signaling pathwayGO:0060828880.013
positive regulation of neurogenesisGO:0050769490.013
positive regulation of protein polymerizationGO:0032273450.013
negative regulation of phosphorus metabolic processGO:00105632670.013
negative regulation of mitotic cell cycle phase transitionGO:1901991850.013
regulation of actin cytoskeleton organizationGO:00329561160.013
negative regulation of cysteine type endopeptidase activity involved in apoptotic processGO:0043154460.013
negative regulation of phosphate metabolic processGO:00459362670.013
regulation of chromatin organizationGO:1902275560.013
ribonucleoside triphosphate catabolic processGO:00092033910.013
regulation of embryonic developmentGO:0045995200.013
divalent inorganic cation transportGO:00725111580.013
regenerationGO:003109940.013
stress activated mapk cascadeGO:0051403930.013
entry into cell of other organism involved in symbiotic interactionGO:0051806250.012
protein modification by small protein removalGO:0070646920.012
response to other organismGO:00517072610.012
regulation of actin filament lengthGO:0030832560.012
interaction with hostGO:0051701420.012
tube morphogenesisGO:0035239950.012
negative regulation of cytokine secretionGO:0050710200.012
regulation of microtubule based processGO:0032886740.012
long term memoryGO:000761620.012
regulation of cellular ketone metabolic processGO:0010565500.012
positive regulation of innate immune responseGO:0045089790.012
positive regulation of cell cycle processGO:00900681060.012
associative learningGO:000830610.012
negative regulation of protein ubiquitinationGO:0031397350.012
negative regulation of nervous system developmentGO:0051961280.012
positive regulation of cell differentiationGO:00455972110.012
spermatid differentiationGO:004851540.012
activation of innate immune responseGO:0002218550.012
hormone metabolic processGO:0042445610.012
apoptotic signaling pathwayGO:00971902680.012
regulation of vesicle mediated transportGO:00606271300.012
regulation of secretion by cellGO:19035301770.012
macroautophagyGO:0016236390.012
negative regulation of transmembrane transportGO:0034763290.012
negative regulation of mitotic cell cycleGO:00459301020.012
meiosis iGO:000712740.012
positive regulation of ubiquitin protein transferase activityGO:0051443180.012
response to misfolded proteinGO:005178850.012
actin filament polymerizationGO:0030041450.012
regulation of transmembrane receptor protein serine threonine kinase signaling pathwayGO:0090092900.012
positive regulation of cell proliferationGO:00082843010.011
regulation of protein k63 linked ubiquitinationGO:190004460.011
regulation of gene expression epigeneticGO:0040029730.011
dna templated transcription elongationGO:0006354250.011
negative regulation of cellular catabolic processGO:0031330830.011
purine ribonucleoside triphosphate catabolic processGO:00092073910.011
cell part morphogenesisGO:00329901370.011
lung alveolus developmentGO:004828640.011
regulation of actin filament based processGO:00329701410.011
protein localization to cell surfaceGO:0034394280.011
cell cycle checkpointGO:00000751170.011
response to biotic stimulusGO:00096072760.011
cellular response to endogenous stimulusGO:00714953360.011
cranial nerve developmentGO:002154540.011
transforming growth factor beta receptor signaling pathwayGO:0007179760.011
cellular response to extracellular stimulusGO:0031668720.011
regulation of androgen receptor signaling pathwayGO:0060765180.011
purine ribonucleoside metabolic processGO:00461284370.011
nucleoside phosphate catabolic processGO:19012924120.011
defense response to virusGO:0051607710.011
regulation of membrane potentialGO:0042391950.011
anterior posterior axis specification embryoGO:000859520.011
nuclear divisionGO:00002801280.011
nucleotide catabolic processGO:00091664080.011
negative regulation of ion transmembrane transportGO:0034766260.011
response to fungusGO:000962040.011
multicellular organismal agingGO:001025930.011
response to axon injuryGO:004867810.011
intrinsic apoptotic signaling pathway in response to dna damageGO:0008630500.011
negative regulation of protein polyubiquitinationGO:190291540.011
cellular response to topologically incorrect proteinGO:0035967190.011
purine nucleotide catabolic processGO:00061954050.011
positive regulation of nervous system developmentGO:0051962540.011
regulation of cellular component movementGO:00512703340.011
single organism cellular localizationGO:19025803320.011
vacuole organizationGO:0007033440.010
visual behaviorGO:000763220.010
negative regulation of response to dna damage stimulusGO:2001021330.010
positive regulation of chromatin modificationGO:1903310300.010
retrograde transport endosome to golgiGO:0042147450.010
positive regulation of cell migrationGO:00303351720.010
negative regulation of cell proliferationGO:00082852280.010
response to alcoholGO:0097305640.010
regulation of intracellular transport of viral materialGO:190125220.010
negative regulation of cellular amine metabolic processGO:003323930.010
cellular homeostasisGO:00197251960.010
positive regulation of cell motilityGO:20001471770.010
establishment of protein localization to membraneGO:00901501210.010
oocyte developmentGO:004859910.010
response to organic cyclic compoundGO:00140702040.010
response to extracellular stimulusGO:0009991850.010
immune response activating cell surface receptor signaling pathwayGO:0002429450.010
negative regulation of protein transportGO:0051224750.010
negative regulation of protein kinase activityGO:0006469980.010
stress activated protein kinase signaling cascadeGO:0031098940.010
organelle fissionGO:00482851490.010
response to transforming growth factor betaGO:0071559940.010
positive regulation of synaptic transmissionGO:005080640.010
forelimb morphogenesisGO:003513640.010
regulation of macroautophagyGO:0016241190.010
microtubule cytoskeleton organizationGO:00002261760.010
cellular response to external stimulusGO:00714961110.010
purine ribonucleoside triphosphate metabolic processGO:00092054110.010

ZNRF1 disease predictions

DiseaseDO term IDSizeProbabilityFunc Analog Org
muscle tissue diseaseDOID:661130.035
muscular diseaseDOID:00800001140.035
musculoskeletal system diseaseDOID:172230.035
sensory system diseaseDOID:00501552030.027
nervous system diseaseDOID:8634310.027
eye and adnexa diseaseDOID:14921500.025
eye diseaseDOID:56141490.025
retinal diseaseDOID:56791180.025
myopathyDOID:4231040.020
retinal degenerationDOID:8466890.018
disease of metabolismDOID:00146672950.015
inherited metabolic disorderDOID:6552420.015
muscular dystrophyDOID:9884510.014
retinitis pigmentosaDOID:10584510.014
limb girdle muscular dystrophyDOID:11724250.014
immune system diseaseDOID:29141550.012
disease of mental healthDOID:150700.012
disease of cellular proliferationDOID:145661740.010
cancerDOID:1621670.010