Homo sapiens

66 known processes

PDE6A

phosphodiesterase 6A, cGMP-specific, rod, alpha

(Aliases: CGPR-A,RP43,PDEA)

PDE6A biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
cation transportGO:00068123310.159
g protein coupled receptor signaling pathwayGO:00071862070.138
lipid metabolic processGO:00066293810.138
cellular amino acid metabolic processGO:00065201160.123
cellular ketone metabolic processGO:0042180800.118
cellular amine metabolic processGO:0044106410.102
ion transmembrane transportGO:00342203380.100
amine metabolic processGO:0009308440.096
transmembrane transportGO:00550853990.095
regulation of transferase activityGO:00513383550.093
chemical homeostasisGO:00488783060.093
post embryonic developmentGO:000979120.087
metal ion transportGO:00300012720.085
regulation of cellular ketone metabolic processGO:0010565500.083
regulation of cellular amine metabolic processGO:0033238110.081
regulation of mapk cascadeGO:00434082620.079
system processGO:00030083490.077
regulation of cellular amino acid metabolic processGO:000652160.076
positive regulation of phosphorylationGO:00423273940.076
cellular response to oxygen containing compoundGO:19017012760.072
anion transportGO:00068201610.069
nucleoside catabolic processGO:00091644080.066
cellular response to endogenous stimulusGO:00714953360.066
positive regulation of mapk cascadeGO:00434101900.064
lipid biosynthetic processGO:00086101770.064
positive regulation of cellular amino acid metabolic processGO:004576430.064
response to oxygen containing compoundGO:19017003690.059
response to nitrogen compoundGO:19016981840.059
sensory perceptionGO:00076001030.058
neurological system processGO:00508771630.058
inorganic ion transmembrane transportGO:00986602310.057
locomotory behaviorGO:000762610.057
negative regulation of multicellular organismal processGO:00512413170.057
cellular lipid metabolic processGO:00442553030.056
positive regulation of cellular amine metabolic processGO:003324070.055
defense responseGO:00069523150.054
positive regulation of protein phosphorylationGO:00019343130.053
immune responseGO:00069553070.052
nitrogen compound transportGO:00717051910.052
regulation of hormone levelsGO:00108171250.052
regulation of ion transportGO:00432691890.051
signal transduction by phosphorylationGO:00230142970.050
secretionGO:00469032540.049
cellular homeostasisGO:00197251960.049
negative regulation of cellular protein metabolic processGO:00322693530.048
female gamete generationGO:000729220.047
response to lipidGO:00339932060.046
regulation of secretion by cellGO:19035301770.046
cation homeostasisGO:00550801890.045
ion homeostasisGO:00508012300.043
response to inorganic substanceGO:00100351270.043
negative regulation of cell deathGO:00605483450.042
purine ribonucleotide catabolic processGO:00091544040.042
Human
purine ribonucleoside metabolic processGO:00461284370.041
negative regulation of protein metabolic processGO:00512483910.041
nucleoside triphosphate catabolic processGO:00091433940.041
nervous system developmentGO:00073992930.039
ribonucleoside catabolic processGO:00424544060.038
epithelium developmentGO:00604292270.038
positive regulation of protein kinase activityGO:00458601900.037
regulation of cell cycleGO:00517263930.037
single organism cellular localizationGO:19025803320.037
ribonucleoside triphosphate catabolic processGO:00092033910.037
positive regulation of kinase activityGO:00336742040.035
negative regulation of catalytic activityGO:00430863350.035
purine containing compound catabolic processGO:00725234110.035
Human
positive regulation of cellular component organizationGO:00511303760.035
regulation of cell cycle processGO:00105642660.035
purine ribonucleoside triphosphate metabolic processGO:00092054110.035
mapk cascadeGO:00001652880.035
ribonucleotide catabolic processGO:00092614050.035
Human
organic anion transportGO:00157111030.035
response to external biotic stimulusGO:00432072610.034
divalent inorganic cation homeostasisGO:00725071360.034
cytoplasmic transportGO:00164823790.034
membrane organizationGO:00610242920.033
organic hydroxy compound metabolic processGO:19016151470.033
inorganic cation transmembrane transportGO:00986621940.033
regulation of nucleotide metabolic processGO:00061402690.033
oogenesisGO:004847720.033
single organism membrane organizationGO:00448022680.033
nucleoside triphosphate metabolic processGO:00091414220.032
rhythmic behaviorGO:000762220.032
regulation of secretionGO:00510461940.032
negative regulation of phosphorus metabolic processGO:00105632670.032
response to biotic stimulusGO:00096072760.032
purine nucleoside catabolic processGO:00061523980.031
anatomical structure formation involved in morphogenesisGO:00486462840.031
cellular component morphogenesisGO:00329893140.031
dephosphorylationGO:00163112090.031
determination of adult lifespanGO:000834020.031
regulation of protein kinase activityGO:00458592890.031
detection of stimulusGO:0051606850.031
cellular chemical homeostasisGO:00550821800.031
positive regulation of cytosolic calcium ion concentrationGO:0007204820.031
cell developmentGO:00484683280.031
multicellular organismal agingGO:001025930.030
steroid metabolic processGO:0008202940.030
response to abiotic stimulusGO:00096283360.030
cellular response to organic cyclic compoundGO:00714071270.030
mitotic cell cycle processGO:19030472860.030
positive regulation of transferase activityGO:00513472270.030
regulation of proteolysisGO:00301622930.030
epithelial cell differentiationGO:00308551410.030
organophosphate catabolic processGO:00464344300.029
Human
negative regulation of programmed cell deathGO:00430693210.029
regulation of cell differentiationGO:00455953930.029
response to organic cyclic compoundGO:00140702040.029
nucleoside phosphate catabolic processGO:19012924120.029
Human
cellular ion homeostasisGO:00068731680.029
regulation of cell developmentGO:00602841610.029
reactive oxygen species metabolic processGO:0072593750.029
muscle system processGO:0003012810.029
response to organonitrogen compoundGO:00102431560.029
cell cell signalingGO:00072671550.029
purine nucleoside triphosphate metabolic processGO:00091444120.029
negative regulation of cellular amine metabolic processGO:003323930.028
generation of neuronsGO:00486991520.028
divalent inorganic cation transportGO:00725111580.028
regulation of response to external stimulusGO:00321012220.028
regulation of metal ion transportGO:00109591200.028
response to other organismGO:00517072610.028
calcium ion homeostasisGO:00550741220.027
regulation of purine nucleotide metabolic processGO:19005422640.027
purine ribonucleoside triphosphate catabolic processGO:00092073910.027
purine ribonucleoside catabolic processGO:00461303980.027
cellular response to lipidGO:00713961270.027
circadian behaviorGO:004851220.027
positive regulation of immune system processGO:00026842830.027
metal ion homeostasisGO:00550651690.027
regulation of kinase activityGO:00435493140.027
purine nucleoside triphosphate catabolic processGO:00091463920.027
negative regulation of developmental processGO:00510932470.026
response to extracellular stimulusGO:0009991850.026
ribonucleoside triphosphate metabolic processGO:00091994120.026
mitotic cell cycleGO:00002783260.026
cation transmembrane transportGO:00986552380.026
regulation of cellular component movementGO:00512703340.026
carbohydrate derivative biosynthetic processGO:19011372070.026
cell morphogenesisGO:00009022960.026
blood circulationGO:00080151130.026
positive regulation of cell deathGO:00109422630.025
positive regulation of developmental processGO:00510943140.025
memoryGO:000761330.025
secretion by cellGO:00329402260.025
positive regulation of transportGO:00510503360.025
response to cytokineGO:00340972320.025
neurogenesisGO:00220081690.025
cellular cation homeostasisGO:00300031630.025
cellular divalent inorganic cation homeostasisGO:00725031280.025
regulation of protein serine threonine kinase activityGO:00719001790.025
glycosyl compound catabolic processGO:19016584130.025
organophosphate biosynthetic processGO:00904071630.025
segmentationGO:003528240.025
biological adhesionGO:00226103310.024
negative regulation of transcription from rna polymerase ii promoterGO:00001222810.024
protein localization to organelleGO:00333652800.024
intracellular protein transportGO:00068862700.024
actin filament based processGO:00300292240.024
protein maturationGO:00516042330.024
cell projection organizationGO:00300302520.024
negative regulation of phosphate metabolic processGO:00459362670.024
regulation of lipid metabolic processGO:0019216960.024
negative regulation of transportGO:00510511760.024
response to growth factorGO:00708482050.024
negative regulation of apoptotic processGO:00430663160.024
protein oligomerizationGO:00512591730.024
protein processingGO:00164852260.024
innate immune responseGO:00450871780.023
response to hormoneGO:00097251750.023
neuromuscular junction developmentGO:000752830.023
multicellular organismal homeostasisGO:0048871670.023
calcium ion transportGO:00068161470.023
behaviorGO:00076101120.023
cell adhesionGO:00071553250.023
regulation of immune responseGO:00507762010.023
positive regulation of hydrolase activityGO:00513453310.023
chromatin organizationGO:00063253510.023
alcohol metabolic processGO:00060661140.023
monocarboxylic acid metabolic processGO:00327871850.022
ras protein signal transductionGO:0007265730.022
oxidation reduction processGO:00551143960.022
cellular calcium ion homeostasisGO:00068741170.022
cellular macromolecular complex assemblyGO:00346223240.022
positive regulation of apoptotic processGO:00430652460.022
urate transportGO:001574730.022
regulation of system processGO:00440571010.022
negative regulation of cellular component organizationGO:00511292350.022
single organism carbohydrate metabolic processGO:00447231930.022
regulation of transmembrane transportGO:00347621390.022
regulation of anatomical structure morphogenesisGO:00226032860.022
small gtpase mediated signal transductionGO:0007264780.022
regulation of cytoskeleton organizationGO:00514931770.022
vesicle mediated transportGO:00161923710.022
negative regulation of cellular amino acid metabolic processGO:004576320.022
associative learningGO:000830610.022
positive regulation of cell proliferationGO:00082843010.022
regulation of locomotionGO:00400123290.022
organ morphogenesisGO:00098871470.021
activation of protein kinase activityGO:0032147900.021
epidermis morphogenesisGO:004873030.021
divalent metal ion transportGO:00708381520.021
cellular metal ion homeostasisGO:00068751460.021
detection of chemical stimulus involved in sensory perceptionGO:0050907330.021
ameboidal type cell migrationGO:00016671350.021
organonitrogen compound biosynthetic processGO:19015662000.021
central nervous system developmentGO:00074171230.021
neuropeptide signaling pathwayGO:0007218190.021
tissue migrationGO:00901301190.021
regulation of intracellular transportGO:00323861950.021
negative regulation of protein processingGO:00109551420.020
regulation of peptidase activityGO:00525471800.020
sensory perception of chemical stimulusGO:0007606380.020
amide transportGO:0042886760.020
negative regulation of protein modification processGO:00314002000.020
positive regulation of catabolic processGO:00098963100.020
response to radiationGO:00093141510.020
adult locomotory behaviorGO:000834410.020
maintenance of locationGO:00512351120.020
matingGO:000761810.020
blood vessel developmentGO:00015681720.020
nucleotide catabolic processGO:00091664080.020
Human
sensory perception of tasteGO:0050909360.020
reactive oxygen species biosynthetic processGO:190340940.019
regulation of sequence specific dna binding transcription factor activityGO:00510902110.019
regulation of transporter activityGO:0032409820.019
rho protein signal transductionGO:0007266260.019
positive regulation of cellular catabolic processGO:00313312840.019
negative regulation of proteolysisGO:00458611320.019
growthGO:00400072020.019
positive regulation of purine nucleotide metabolic processGO:19005442270.019
positive regulation of organelle organizationGO:00106381950.019
positive regulation of cell differentiationGO:00455972110.019
circulatory system developmentGO:00723592620.019
protein modification by small protein conjugationGO:00324463420.019
protein catabolic processGO:00301633250.019
protein targetingGO:00066051870.019
atp metabolic processGO:00460341760.019
cell growthGO:00160491600.019
blood vessel morphogenesisGO:00485141620.019
small molecule biosynthetic processGO:00442831570.019
anion transmembrane transportGO:0098656760.019
defense response to other organismGO:00985421290.019
activation of mapk activityGO:0000187450.019
regulation of reactive oxygen species metabolic processGO:2000377410.019
blastoderm segmentationGO:000735020.019
cellular response to cytokine stimulusGO:00713451810.018
positive regulation of protein serine threonine kinase activityGO:00719021190.018
vasculature developmentGO:00019441810.018
anatomical structure homeostasisGO:00602491000.018
visual behaviorGO:000763220.018
epithelium migrationGO:00901321190.018
hindbrain developmentGO:003090230.018
regulation of protein localizationGO:00328802960.018
actin cytoskeleton organizationGO:00300362070.018
regulation of cell growthGO:00015581350.018
cell divisionGO:00513011680.018
regulation of homeostatic processGO:00328441210.018
organic hydroxy compound biosynthetic processGO:1901617710.018
atp catabolic processGO:00062001570.018
cell part morphogenesisGO:00329901370.018
nucleotide biosynthetic processGO:00091651090.018
morphogenesis of embryonic epitheliumGO:001633140.018
regulation of vesicle mediated transportGO:00606271300.018
sensory perception of painGO:001923340.018
angiogenesisGO:00015251470.018
inner ear morphogenesisGO:004247240.017
actin filament based movementGO:0030048170.017
regulation of endopeptidase activityGO:00525481700.017
nucleoside monophosphate catabolic processGO:00091251590.017
carbohydrate metabolic processGO:00059752070.017
peptide transportGO:0015833740.017
enzyme linked receptor protein signaling pathwayGO:00071673030.017
purine ribonucleoside monophosphate metabolic processGO:00091671860.017
regulation of transmembrane transporter activityGO:0022898740.017
regenerationGO:003109940.017
response to light stimulusGO:0009416870.017
detection of chemical stimulusGO:0009593550.017
regulation of cytokine productionGO:00018172320.017
monovalent inorganic cation transportGO:00156721280.017
purine nucleotide catabolic processGO:00061954050.017
Human
angiotensin activated signaling pathwayGO:003816640.017
response to metal ionGO:0010038840.017
ribonucleoside monophosphate metabolic processGO:00091611870.017
regulation of mitotic cell cycleGO:00073461890.017
response to nutrient levelsGO:0031667810.017
organic hydroxy compound transportGO:0015850630.017
regulation of calcium ion transportGO:0051924790.016
regulation of cellular component biogenesisGO:00440872810.016
sequestering of metal ionGO:0051238240.016
epithelial cell migrationGO:00106311190.016
regulation of multi organism processGO:00439001570.016
regulation of protein processingGO:00706131500.016
cellular macromolecule catabolic processGO:00442653800.016
positive regulation of programmed cell deathGO:00430682490.016
regulation of ion transmembrane transporter activityGO:0032412720.016
negative regulation of protein maturationGO:19033181420.016
regulation of growthGO:00400081650.016
regulation of protein transportGO:00512232130.016
regulation of actin filament based processGO:00329701410.016
salivary gland morphogenesisGO:000743540.016
gtp metabolic processGO:00460392390.016
hormone metabolic processGO:0042445610.016
organelle assemblyGO:00709251760.016
purine nucleoside monophosphate metabolic processGO:00091261860.016
positive regulation of immune responseGO:00507781590.016
regulation of reactive oxygen species biosynthetic processGO:190342630.016
microtubule based processGO:00070172100.016
epithelial cell proliferationGO:00506731280.016
regulation of nucleotide catabolic processGO:00308112050.016
detection of stimulus involved in sensory perceptionGO:0050906430.016
sulfur compound metabolic processGO:00067901010.016
cell activationGO:00017752130.016
regulation of nucleoside metabolic processGO:00091182090.016
regulation of anatomical structure sizeGO:00900661010.016
regulation of meiotic cell cycleGO:005144540.016
histone modificationGO:00165702510.016
guanosine containing compound catabolic processGO:19010692390.016
nucleoside monophosphate metabolic processGO:00091231910.016
regulation of synaptic plasticityGO:004816730.016
response to bacteriumGO:00096171440.016
neuron differentiationGO:00301821380.015
steroid biosynthetic processGO:0006694460.015
protein localization to nucleusGO:00345041360.015
embryonic epithelial tube formationGO:000183840.015
tachykinin receptor signaling pathwayGO:000721730.015
peripheral nervous system developmentGO:000742220.015
negative regulation of cell differentiationGO:00455961710.015
regulation of purine nucleotide catabolic processGO:00331212050.015
regulation of protein maturationGO:19033171500.015
regulation of establishment of protein localizationGO:00702012420.015
covalent chromatin modificationGO:00165692540.015
microtubule cytoskeleton organizationGO:00002261760.015
posttranscriptional regulation of gene expressionGO:00106082130.015
phospholipid metabolic processGO:0006644990.015
lipid transportGO:0006869900.015
response to virusGO:00096151260.015
neuron projection developmentGO:00311751060.015
micturitionGO:006007330.015
spermatid differentiationGO:004851540.015
copulationGO:000762010.015
protein ubiquitinationGO:00165673140.015
negative regulation of phosphorylationGO:00423261740.015
cell projection morphogenesisGO:00488581290.015
cellular protein complex assemblyGO:00436231880.015
nucleocytoplasmic transportGO:00069131760.015
chromatin modificationGO:00165682980.015
regulation of cell motilityGO:20001452990.015
negative regulation of intracellular signal transductionGO:19025321830.015
positive regulation of nucleotide metabolic processGO:00459812300.015
negative regulation of cell proliferationGO:00082852280.015
reproductive processGO:00224141060.015
peptidyl tyrosine modificationGO:00182121700.015
ribonucleoside monophosphate catabolic processGO:00091581580.015
dna repairGO:00062811980.015
ossificationGO:00015031210.015
chloride transportGO:0006821410.015
negative regulation of organelle organizationGO:00106391260.015
negative regulation of transferase activityGO:00513481240.015
response to acid chemicalGO:0001101660.014
cellular response to dna damage stimulusGO:00069743790.014
immune system developmentGO:00025201950.014
cellular response to external stimulusGO:00714961110.014
regulation of leukocyte activationGO:00026941150.014
positive regulation of reactive oxygen species biosynthetic processGO:190342820.014
cellular response to growth factor stimulusGO:00713631970.014
oocyte developmentGO:004859910.014
cytosolic calcium ion homeostasisGO:0051480890.014
reactive nitrogen species metabolic processGO:200105730.014
positive regulation of hormone biosynthetic processGO:004688640.014
nuclear transportGO:00511691790.014
detection of chemical stimulus involved in sensory perception of tasteGO:0050912310.014
signal releaseGO:0023061700.014
regulation of cell activationGO:00508651250.014
taxisGO:00423301570.014
single organism cell adhesionGO:00986021790.014
organelle fissionGO:00482851490.014
positive regulation of map kinase activityGO:0043406800.014
response to woundingGO:00096111680.014
glycerolipid metabolic processGO:00464861070.014
purine ribonucleoside monophosphate catabolic processGO:00091691580.014
establishment of protein localization to organelleGO:00725941720.014
negative regulation of hydrolase activityGO:00513461820.014
cellular response to abiotic stimulusGO:00712141170.014
purine nucleoside monophosphate catabolic processGO:00091281580.014
regulation of cellular response to stressGO:00801352440.014
regulation of behaviorGO:0050795820.014
regulation of defense responseGO:00313471540.014
negative regulation of secretion by cellGO:1903531520.014
peptide secretionGO:0002790510.014
hematopoietic or lymphoid organ developmentGO:00485341860.014
positive regulation of cell cycleGO:00457871400.014
regulation of membrane potentialGO:0042391950.014
visual learningGO:000854210.014
cardiovascular system developmentGO:00723582620.014
mesenchymal to epithelial transition involved in metanephros morphogenesisGO:000333740.014
positive regulation of cell cycle processGO:00900681060.013
cell cycle phase transitionGO:00447701730.013
organic acid transportGO:0015849650.013
response to salt stressGO:000965130.013
alpha ketoglutarate transportGO:001574210.013
regulation of body fluid levelsGO:0050878990.013
regulation of i kappab kinase nf kappab signalingGO:00431221620.013
photoreceptor cell differentiationGO:004653020.013
positive regulation of nucleotide catabolic processGO:00308131850.013
regulation of cell divisionGO:00513021160.013
positive regulation of leukocyte activationGO:0002696800.013
regulation of actin cytoskeleton organizationGO:00329561160.013
regulation of map kinase activityGO:00434051080.013
regulation of cytoplasmic transportGO:19036491490.013
apoptotic signaling pathwayGO:00971902680.013
spermatid developmentGO:000728640.013
positive regulation of reactive oxygen species metabolic processGO:2000379240.013
regulation of dna metabolic processGO:00510521530.013
peptidyl tyrosine phosphorylationGO:00181081700.013
regulation of protein catabolic processGO:00421761550.013
regulation of lymphocyte activationGO:00512491030.013
positive regulation of purine nucleotide catabolic processGO:00331231850.013
inorganic anion transmembrane transportGO:0098661470.013
motor neuron axon guidanceGO:000804520.013
guanosine containing compound metabolic processGO:19010682440.013
cellular protein catabolic processGO:00442572610.013
multi organism cellular processGO:00447641560.013
neuron developmentGO:00486661130.013
short chain fatty acid importGO:001591310.013
positive regulation of nucleoside metabolic processGO:00459791860.013
positive regulation of ion transportGO:0043270870.013
cytokine productionGO:00018162470.013
response to fungusGO:000962040.013
cellular response to nitrogen compoundGO:19016991440.013
myeloid cell differentiationGO:00300991170.013
negative regulation of cell growthGO:0030308830.013
regulation of epithelial cell migrationGO:0010632930.013
inorganic anion transportGO:0015698600.013
anterior posterior axis specificationGO:000994820.013
hair follicle morphogenesisGO:003106920.013
negative regulation of peptidase activityGO:0010466910.013
regulation of meiosisGO:004002030.013
positive regulation of cell migrationGO:00303351720.013
negative regulation of synaptic transmissionGO:005080520.013
purine containing compound biosynthetic processGO:0072522880.013
response to axon injuryGO:004867810.013
circulatory system processGO:00030131130.013
positive regulation of cell developmentGO:0010720920.012
regulation of apoptotic signaling pathwayGO:20012331750.012
chemotaxisGO:00069351570.012
compound eye developmentGO:004874910.012
positive regulation of synaptic transmissionGO:005080640.012
cell morphogenesis involved in differentiationGO:00009041440.012
single organism reproductive processGO:0044702980.012
regulation of gtp catabolic processGO:00331241800.012
negative regulation of growthGO:0045926970.012
positive regulation of acrosome reactionGO:200034440.012
carnitine transmembrane transportGO:190260330.012
regulation of cell projection organizationGO:00313441070.012
carboxylic acid transportGO:0046942630.012
regulation of acrosome reactionGO:006004640.012
regulation of ion transmembrane transportGO:00347651320.012
skeletal system developmentGO:0001501790.012
cyclic nucleotide biosynthetic processGO:0009190610.012
gtp catabolic processGO:00061842370.012
cell type specific apoptotic processGO:00972851250.012
negative regulation of endopeptidase activityGO:0010951840.012
cellular response to hormone stimulusGO:00328701250.012
proteolysis involved in cellular protein catabolic processGO:00516032440.012
nerve developmentGO:002167540.012
positive regulation of cell motilityGO:20001471770.012
lymphocyte activationGO:00466491330.012
intracellular receptor signaling pathwayGO:00305221040.012
protein importGO:00170381300.012
wound healingGO:00420601150.012
leukocyte activationGO:00453211640.012
muscle contractionGO:0006936730.012
establishment of protein localization to membraneGO:00901501210.012
embryonic hemopoiesisGO:003516240.012

PDE6A disease predictions

DiseaseDO term IDSizeProbabilityFunc Analog Org
sensory system diseaseDOID:00501552030.073
nervous system diseaseDOID:8634310.073
eye diseaseDOID:56141490.051
retinal diseaseDOID:56791180.051
eye and adnexa diseaseDOID:14921500.051
disease of metabolismDOID:00146672950.032
central nervous system diseaseDOID:3311860.029
musculoskeletal system diseaseDOID:172230.023
disease of cellular proliferationDOID:145661740.022
organ system cancerDOID:00506861640.022
cancerDOID:1621670.022
retinal degenerationDOID:8466890.019
inherited metabolic disorderDOID:6552420.017
neurodegenerative diseaseDOID:12891020.016
night blindnessDOID:8499100.014
Human
connective tissue diseaseDOID:651090.013
bone diseaseDOID:0080001880.013
immune system diseaseDOID:29141550.013