Homo sapiens

0 known processes

RCAN1

regulator of calcineurin 1

(Aliases: RCN1,MCIP1,ADAPT78,DSCR1,DSC1,CSP1)

RCAN1 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
post embryonic developmentGO:000979120.094
amine metabolic processGO:0009308440.080
cellular lipid metabolic processGO:00442553030.074
regulation of cellular component movementGO:00512703340.071
regulation of cellular amino acid metabolic processGO:000652160.070
lipid metabolic processGO:00066293810.066
system processGO:00030083490.065
Mouse
response to abiotic stimulusGO:00096283360.065
Rat
cellular amino acid metabolic processGO:00065201160.065
defense responseGO:00069523150.061
actin filament based processGO:00300292240.058
cell adhesionGO:00071553250.057
regulation of cell differentiationGO:00455953930.057
Rat
cardiovascular system developmentGO:00723582620.057
biological adhesionGO:00226103310.055
circulatory system developmentGO:00723592620.053
cation transportGO:00068123310.053
regulation of locomotionGO:00400123290.053
positive regulation of cellular component organizationGO:00511303760.053
positive regulation of cell proliferationGO:00082843010.052
regulation of cell motilityGO:20001452990.052
immune responseGO:00069553070.052
regulation of cellular component biogenesisGO:00440872810.052
cellular amine metabolic processGO:0044106410.051
cell developmentGO:00484683280.051
Mouse
female gamete generationGO:000729220.051
response to oxygen containing compoundGO:19017003690.050
regulation of cellular amine metabolic processGO:0033238110.049
nucleoside catabolic processGO:00091644080.047
organonitrogen compound biosynthetic processGO:19015662000.047
regulation of cellular ketone metabolic processGO:0010565500.047
metal ion transportGO:00300012720.046
determination of adult lifespanGO:000834020.046
multicellular organismal agingGO:001025930.046
regulation of cell cycleGO:00517263930.045
negative regulation of cellular protein metabolic processGO:00322693530.045
purine containing compound catabolic processGO:00725234110.045
regulation of cell migrationGO:00303342890.045
response to organic cyclic compoundGO:00140702040.044
Rat
anatomical structure formation involved in morphogenesisGO:00486462840.044
negative regulation of protein metabolic processGO:00512483910.044
nucleoside triphosphate metabolic processGO:00091414220.043
cellular response to oxygen containing compoundGO:19017012760.042
regulation of protein localizationGO:00328802960.042
angiogenesisGO:00015251470.042
negative regulation of programmed cell deathGO:00430693210.042
positive regulation of cellular amino acid metabolic processGO:004576430.041
regulation of transferase activityGO:00513383550.041
purine nucleoside catabolic processGO:00061523980.041
negative regulation of catalytic activityGO:00430863350.041
Worm
oogenesisGO:004847720.041
purine nucleoside triphosphate metabolic processGO:00091444120.041
purine ribonucleoside catabolic processGO:00461303980.041
purine ribonucleoside triphosphate catabolic processGO:00092073910.040
purine ribonucleotide catabolic processGO:00091544040.040
associative learningGO:000830610.040
transmembrane transportGO:00550853990.040
negative regulation of cell deathGO:00605483450.040
enzyme linked receptor protein signaling pathwayGO:00071673030.039
positive regulation of developmental processGO:00510943140.039
positive regulation of cell motilityGO:20001471770.039
positive regulation of hydrolase activityGO:00513453310.039
regulation of proteolysisGO:00301622930.039
cellular ketone metabolic processGO:0042180800.039
positive regulation of phosphorylationGO:00423273940.039
epithelium developmentGO:00604292270.039
blood vessel morphogenesisGO:00485141620.039
purine ribonucleoside triphosphate metabolic processGO:00092054110.038
regulation of kinase activityGO:00435493140.038
chemical homeostasisGO:00488783060.038
organophosphate catabolic processGO:00464344300.038
purine nucleotide catabolic processGO:00061954050.038
cytoplasmic transportGO:00164823790.038
ribonucleotide catabolic processGO:00092614050.038
secretionGO:00469032540.037
regulation of establishment of protein localizationGO:00702012420.037
nucleotide catabolic processGO:00091664080.037
purine ribonucleoside metabolic processGO:00461284370.037
regulation of cell adhesionGO:00301551660.037
ribonucleoside triphosphate metabolic processGO:00091994120.037
nucleoside phosphate catabolic processGO:19012924120.037
vasculature developmentGO:00019441810.037
reactive oxygen species metabolic processGO:0072593750.036
single organism cellular localizationGO:19025803320.036
single organism cell adhesionGO:00986021790.036
neurological system processGO:00508771630.036
Mouse
locomotory behaviorGO:000762610.036
Mouse
positive regulation of locomotionGO:00400171860.036
positive regulation of cellular amine metabolic processGO:003324070.035
cell projection organizationGO:00300302520.035
single organismal cell cell adhesionGO:00163371480.035
cellular response to growth factor stimulusGO:00713631970.035
positive regulation of cell deathGO:00109422630.034
ribonucleoside triphosphate catabolic processGO:00092033910.034
positive regulation of transportGO:00510503360.034
neuromuscular junction developmentGO:000752830.034
regulation of protein transportGO:00512232130.034
negative regulation of multicellular organismal processGO:00512413170.034
mitotic cell cycleGO:00002783260.034
cellular component morphogenesisGO:00329893140.034
regenerationGO:003109940.033
segmentationGO:003528240.033
response to cytokineGO:00340972320.033
nucleoside triphosphate catabolic processGO:00091433940.033
negative regulation of phosphorus metabolic processGO:00105632670.033
Worm
cellular response to endogenous stimulusGO:00714953360.033
nervous system developmentGO:00073992930.033
positive regulation of cellular component movementGO:00512721810.033
response to woundingGO:00096111680.033
glycosyl compound catabolic processGO:19016584130.033
cell morphogenesisGO:00009022960.032
positive regulation of cell migrationGO:00303351720.032
mapk cascadeGO:00001652880.032
protein maturationGO:00516042330.031
membrane organizationGO:00610242920.031
response to nitrogen compoundGO:19016981840.031
positive regulation of protein kinase activityGO:00458601900.031
vesicle mediated transportGO:00161923710.031
response to organonitrogen compoundGO:00102431560.031
positive regulation of protein phosphorylationGO:00019343130.031
intracellular protein transportGO:00068862700.031
response to hormoneGO:00097251750.031
Rat
positive regulation of apoptotic processGO:00430652460.031
negative regulation of apoptotic processGO:00430663160.031
purine nucleoside triphosphate catabolic processGO:00091463920.030
blood vessel developmentGO:00015681720.030
growthGO:00400072020.030
cellular macromolecule catabolic processGO:00442653800.030
protein catabolic processGO:00301633250.030
apoptotic signaling pathwayGO:00971902680.029
anion transportGO:00068201610.029
regulation of protein kinase activityGO:00458592890.029
positive regulation of cell differentiationGO:00455972110.029
negative regulation of cellular amine metabolic processGO:003323930.029
positive regulation of catabolic processGO:00098963100.029
cytokine productionGO:00018162470.029
oocyte differentiationGO:000999420.029
negative regulation of transcription from rna polymerase ii promoterGO:00001222810.029
negative regulation of cellular component organizationGO:00511292350.029
reactive nitrogen species metabolic processGO:200105730.029
small gtpase mediated signal transductionGO:0007264780.029
regulation of secretionGO:00510461940.029
response to biotic stimulusGO:00096072760.029
regulation of cell growthGO:00015581350.029
positive regulation of immune system processGO:00026842830.029
oxidation reduction processGO:00551143960.028
wound healingGO:00420601150.028
actin cytoskeleton organizationGO:00300362070.028
secretion by cellGO:00329402260.028
memoryGO:000761330.028
Mouse
cell activationGO:00017752130.028
ribonucleoside catabolic processGO:00424544060.028
regulation of cellular response to stressGO:00801352440.028
epithelial cell migrationGO:00106311190.028
nerve developmentGO:002167540.027
protein processingGO:00164852260.027
regulation of cytokine productionGO:00018172320.027
tissue migrationGO:00901301190.027
regulation of anatomical structure morphogenesisGO:00226032860.027
ras protein signal transductionGO:0007265730.027
lipid biosynthetic processGO:00086101770.027
ion transmembrane transportGO:00342203380.027
ion homeostasisGO:00508012300.027
organ morphogenesisGO:00098871470.027
response to growth factorGO:00708482050.027
response to other organismGO:00517072610.026
positive regulation of cellular catabolic processGO:00313312840.026
cellular homeostasisGO:00197251960.026
organic anion transportGO:00157111030.026
regulation of mapk cascadeGO:00434082620.026
regulation of cytoskeleton organizationGO:00514931770.026
anterior posterior axis specificationGO:000994820.026
dephosphorylationGO:00163112090.026
Mouse Worm
carbohydrate derivative biosynthetic processGO:19011372070.026
hindbrain developmentGO:003090230.026
positive regulation of transferase activityGO:00513472270.026
oocyte developmentGO:004859910.026
single organism membrane organizationGO:00448022680.026
signal transduction by phosphorylationGO:00230142970.026
ameboidal type cell migrationGO:00016671350.026
cellular chemical homeostasisGO:00550821800.025
negative regulation of hydrolase activityGO:00513461820.025
Worm
negative regulation of transportGO:00510511760.025
small molecule biosynthetic processGO:00442831570.025
cell growthGO:00160491600.025
protein localization to organelleGO:00333652800.025
mitotic cell cycle processGO:19030472860.025
cranial nerve developmentGO:002154540.025
negative regulation of cellular amino acid metabolic processGO:004576320.025
regulation of peptidase activityGO:00525471800.025
regulation of reactive oxygen species metabolic processGO:2000377410.025
hemopoiesisGO:00300971800.025
regulation of reactive oxygen species biosynthetic processGO:190342630.025
maintenance of locationGO:00512351120.025
cellular protein catabolic processGO:00442572610.024
blastoderm segmentationGO:000735020.024
negative regulation of developmental processGO:00510932470.024
Rat
reactive oxygen species biosynthetic processGO:190340940.024
developmental programmed cell deathGO:001062330.024
protein modification by small protein conjugationGO:00324463420.024
cellular macromolecular complex assemblyGO:00346223240.024
positive regulation of organelle organizationGO:00106381950.024
regulation of nucleotide metabolic processGO:00061402690.023
cellular response to cytokine stimulusGO:00713451810.023
regulation of secretion by cellGO:19035301770.023
tripartite regional subdivisionGO:000735120.023
regulation of endopeptidase activityGO:00525481700.023
response to metal ionGO:0010038840.023
positive regulation of nucleotide catabolic processGO:00308131850.023
proteolysis involved in cellular protein catabolic processGO:00516032440.023
endothelial cell migrationGO:0043542860.023
negative regulation of phosphate metabolic processGO:00459362670.023
Worm
positive regulation of mapk cascadeGO:00434101900.023
epithelial cell differentiationGO:00308551410.023
transmembrane receptor protein tyrosine kinase signaling pathwayGO:00071691810.023
positive regulation of nucleotide metabolic processGO:00459812300.022
regulation of protein processingGO:00706131500.022
anterior posterior axis specification embryoGO:000859520.022
regulation of ion transportGO:00432691890.022
regulation of synaptic plasticityGO:004816730.022
positive regulation of kinase activityGO:00336742040.022
response to external biotic stimulusGO:00432072610.022
ribonucleoside monophosphate metabolic processGO:00091611870.022
circadian behaviorGO:004851220.022
rhythmic behaviorGO:000762220.022
epithelium migrationGO:00901321190.022
rho protein signal transductionGO:0007266260.022
response to lipidGO:00339932060.022
Rat
morphogenesis of embryonic epitheliumGO:001633140.022
lipid localizationGO:00108761060.022
generation of neuronsGO:00486991520.021
positive regulation of reactive oxygen species biosynthetic processGO:190342820.021
regulation of epithelial cell migrationGO:0010632930.021
regulation of cell cycle processGO:00105642660.021
protein targetingGO:00066051870.021
regulation of cell morphogenesisGO:00226041530.021
nitrogen compound transportGO:00717051910.021
guanosine containing compound catabolic processGO:19010692390.021
fatty acid metabolic processGO:00066311150.021
single organism carbohydrate metabolic processGO:00447231930.021
cellular response to glucocorticoid stimulusGO:007138540.021
monocarboxylic acid metabolic processGO:00327871850.021
gtp metabolic processGO:00460392390.021
neurogenesisGO:00220081690.021
negative regulation of intracellular signal transductionGO:19025321830.021
taxisGO:00423301570.021
actin filament organizationGO:00070151280.021
regulation of growthGO:00400081650.020
response to axon injuryGO:004867810.020
positive regulation of protein transportGO:00512221350.020
regulation of keratinocyte migrationGO:005154740.020
regulation of actin filament based processGO:00329701410.020
hematopoietic or lymphoid organ developmentGO:00485341860.020
positive regulation of proteolysisGO:00458621420.020
regulation of intracellular transportGO:00323861950.020
cell substrate adhesionGO:00315891320.020
peripheral nervous system developmentGO:000742220.020
regulation of vasculature developmentGO:1901342970.020
regulation of anatomical structure sizeGO:00900661010.020
endomembrane system organizationGO:00102561960.020
negative regulation of locomotionGO:00400131180.020
carbohydrate metabolic processGO:00059752070.019
embryonic epithelial tube formationGO:000183840.019
purine ribonucleoside monophosphate metabolic processGO:00091671860.019
monovalent inorganic cation transportGO:00156721280.019
positive regulation of reactive oxygen species metabolic processGO:2000379240.019
cation homeostasisGO:00550801890.019
regulation of cysteine type endopeptidase activity involved in apoptotic processGO:00432811160.019
organophosphate biosynthetic processGO:00904071630.019
regulation of immune responseGO:00507762010.019
neural tube formationGO:000184130.019
regulation of cell developmentGO:00602841610.019
positive regulation of cytokine productionGO:00018191670.019
negative regulation of cell cycleGO:00457861930.019
purine nucleoside monophosphate metabolic processGO:00091261860.019
negative regulation of cell proliferationGO:00082852280.019
cellular cation homeostasisGO:00300031630.019
organic hydroxy compound metabolic processGO:19016151470.019
cell cell signalingGO:00072671550.019
cellular response to nitrogen compoundGO:19016991440.019
positive regulation of purine nucleotide metabolic processGO:19005442270.019
inorganic ion transmembrane transportGO:00986602310.019
proteasomal protein catabolic processGO:00104981760.019
neurotransmitter secretionGO:000726940.019
regulation of purine nucleotide catabolic processGO:00331212050.019
regulation of cysteine type endopeptidase activityGO:20001161270.019
ubiquitin dependent protein catabolic processGO:00065112060.018
cellular protein complex assemblyGO:00436231880.018
regulation of response to external stimulusGO:00321012220.018
positive regulation of synaptic transmissionGO:005080640.018
motor neuron axon guidanceGO:000804520.018
chemotaxisGO:00069351570.018
innate immune responseGO:00450871780.018
atp metabolic processGO:00460341760.018
adult locomotory behaviorGO:000834410.018
muscle system processGO:0003012810.018
positive regulation of programmed cell deathGO:00430682490.018
cardiac muscle cell contractionGO:008600340.018
nucleoside monophosphate metabolic processGO:00091231910.018
cellular response to hormone stimulusGO:00328701250.018
response to inorganic substanceGO:00100351270.018
cellular response to organic cyclic compoundGO:00714071270.018
alcohol metabolic processGO:00060661140.018
regulation of response to woundingGO:19030341010.018
regulation of protein maturationGO:19033171500.018
cell cycle phase transitionGO:00447701730.018
epithelial cell proliferationGO:00506731280.017
neuron projection regenerationGO:003110210.017
tube developmentGO:00352951250.017
establishment of protein localization to organelleGO:00725941720.017
negative regulation of protein modification processGO:00314002000.017
immune system developmentGO:00025201950.017
regulation of mitotic cell cycleGO:00073461890.017
myeloid cell differentiationGO:00300991170.017
compound eye developmentGO:004874910.017
cellular response to dna damage stimulusGO:00069743790.017
neural crest cell developmentGO:001403230.017
divalent metal ion transportGO:00708381520.017
negative regulation of cell migrationGO:00303361020.017
microtubule based processGO:00070172100.017
gtp catabolic processGO:00061842370.017
glycerolipid metabolic processGO:00464861070.017
primary neural tube formationGO:001402030.017
chondroblast differentiationGO:006059120.017
divalent inorganic cation transportGO:00725111580.017
calcium ion transportGO:00068161470.017
regulation of nucleotide catabolic processGO:00308112050.017
purine nucleoside monophosphate catabolic processGO:00091281580.017
protein ubiquitinationGO:00165673140.017
negative regulation of cell motilityGO:20001461040.017
positive regulation of cellular component biogenesisGO:00440891580.017
guanosine containing compound metabolic processGO:19010682440.017
regulation of purine nucleotide metabolic processGO:19005422640.016
spermatid differentiationGO:004851540.016
response to fungusGO:000962040.016
cell projection morphogenesisGO:00488581290.016
modification dependent macromolecule catabolic processGO:00436322120.016
circulatory system processGO:00030131130.016
erk1 and erk2 cascadeGO:00703711040.016
cyclic nucleotide metabolic processGO:0009187820.016
negative regulation of phosphorylationGO:00423261740.016
inorganic cation transmembrane transportGO:00986621940.016
regulation of angiogenesisGO:0045765920.016
post embryonic organ developmentGO:004856910.016
regulation of multi organism processGO:00439001570.016
regulation of nucleoside metabolic processGO:00091182090.016
negative regulation of protein processingGO:00109551420.016
carboxylic acid biosynthetic processGO:0046394970.016
positive regulation of purine nucleotide catabolic processGO:00331231850.016
cation transmembrane transportGO:00986552380.016
cellular ion homeostasisGO:00068731680.016
spermatid developmentGO:000728640.016
proteasome mediated ubiquitin dependent protein catabolic processGO:00431611560.016
blood circulationGO:00080151130.016
positive regulation of nucleoside metabolic processGO:00459791860.016
modification dependent protein catabolic processGO:00199412090.016
regulation of vesicle mediated transportGO:00606271300.016
cell divisionGO:00513011680.016
protein localization to membraneGO:00726571600.016
limbic system developmentGO:002176130.016
sleepGO:003043120.016
organic acid biosynthetic processGO:0016053970.016
purine ribonucleoside monophosphate catabolic processGO:00091691580.016
negative regulation of cellular component movementGO:00512711060.016
inflammatory responseGO:0006954790.015
response to oxidative stressGO:00069791210.015
Mouse
lipid transportGO:0006869900.015
membrane lipid metabolic processGO:0006643530.015
nucleocytoplasmic transportGO:00069131760.015
negative regulation of cell differentiationGO:00455961710.015
Rat
immune effector processGO:00022521590.015
phospholipid metabolic processGO:0006644990.015
glycoprotein metabolic processGO:00091001100.015
mitotic cell cycle phase transitionGO:00447721620.015
regulation of metal ion transportGO:00109591200.015
positive regulation of gliogenesisGO:001401540.015
nuclear transportGO:00511691790.015
regulation of protein serine threonine kinase activityGO:00719001790.015
cell part morphogenesisGO:00329901370.015
embryo developmentGO:00097901230.015
regulation of actin cytoskeleton organizationGO:00329561160.015
lung alveolus developmentGO:004828640.015
negative regulation of protein maturationGO:19033181420.015
ribonucleoside monophosphate catabolic processGO:00091581580.015
cellular response to abiotic stimulusGO:00712141170.015
regulation of i kappab kinase nf kappab signalingGO:00431221620.015
regulation of protein catabolic processGO:00421761550.015
regulation of apoptotic signaling pathwayGO:20012331750.015
regulation of hormone levelsGO:00108171250.015
regulation of defense responseGO:00313471540.015
nucleoside monophosphate catabolic processGO:00091251590.015
glycoprotein biosynthetic processGO:0009101910.015
visual behaviorGO:000763220.015
posttranscriptional regulation of gene expressionGO:00106082130.015
positive regulation of gtpase activityGO:00435471660.015
behaviorGO:00076101120.015
Mouse
cellular metal ion homeostasisGO:00068751460.015
atp catabolic processGO:00062001570.015
tissue regenerationGO:004224630.014
actin filament based movementGO:0030048170.014
mitochondrion organizationGO:00070051560.014
regulation of ossificationGO:0030278580.014
cellular component assembly involved in morphogenesisGO:0010927730.014
response to drugGO:0042493810.014
regulation of cell projection organizationGO:00313441070.014
actin mediated cell contractionGO:0070252120.014
regulation of dna metabolic processGO:00510521530.014
regulation of glial cell differentiationGO:004568530.014
cellular response to organonitrogen compoundGO:00714171240.014
regulation of meiotic cell cycleGO:005144540.014
response to radiationGO:00093141510.014
neuroblast proliferationGO:000740540.014
cell projection assemblyGO:00300311260.014
negative regulation of cytokine productionGO:0001818820.014
positive regulation of secretionGO:00510471160.014
microtubule cytoskeleton organizationGO:00002261760.014
tube closureGO:006060630.014
protein oligomerizationGO:00512591730.014
transmembrane receptor protein serine threonine kinase signaling pathwayGO:00071781250.014
response to oxygen levelsGO:00704821000.014
inner ear morphogenesisGO:004247240.014
response to decreased oxygen levelsGO:0036293960.014
nucleotide biosynthetic processGO:00091651090.014
regulation of homeostatic processGO:00328441210.014
cellular response to lipidGO:00713961270.014
regulation of sequence specific dna binding transcription factor activityGO:00510902110.014
organ formationGO:004864530.014
positive regulation of peptidase activityGO:0010952880.014
regulation of protein complex assemblyGO:00432541470.014
leukocyte activationGO:00453211640.014
g protein coupled receptor signaling pathwayGO:00071862070.014
positive regulation of intracellular transportGO:00323881040.014
visual learningGO:000854210.014
regulation of protein secretionGO:0050708860.013
reproductive processGO:00224141060.013
tube morphogenesisGO:0035239950.013
neuron developmentGO:00486661130.013
negative regulation of growthGO:0045926970.013
tissue morphogenesisGO:0048729960.013
ossificationGO:00015031210.013
metal ion homeostasisGO:00550651690.013
organelle assemblyGO:00709251760.013
regulation of gtp catabolic processGO:00331241800.013
regulation of cytoplasmic transportGO:19036491490.013
response to nutrient levelsGO:0031667810.013
sensory perception of painGO:001923340.013
neural tube closureGO:000184330.013
rna interferenceGO:001624640.013
regulation of intracellular protein transportGO:00331571230.013
positive regulation of cytoskeleton organizationGO:0051495830.013
cytokine mediated signaling pathwayGO:00192211090.013
regulation of dephosphorylationGO:0035303960.013
Mouse Worm
endosomal transportGO:00161971290.013
response to bacteriumGO:00096171440.013
regulation of neural precursor cell proliferationGO:200017740.013
embryonic placenta developmentGO:000189210.013
regulation of ras gtpase activityGO:00323181280.013
hemostasisGO:0007599760.013
regulation of transmembrane transportGO:00347621390.013
regulation of map kinase activityGO:00434051080.013
stress activated mapk cascadeGO:0051403930.013
regulation of membrane potentialGO:0042391950.013
interspecies interaction between organismsGO:00444191560.013
cellular response to external stimulusGO:00714961110.013
negative regulation of cell adhesionGO:0007162640.013
response to activityGO:001482300.013
positive regulation of immune responseGO:00507781590.013
cell junction organizationGO:0034330790.013
regulation of body fluid levelsGO:0050878990.013
positive regulation of intracellular protein transportGO:0090316760.013
axon regenerationGO:003110310.013
negative regulation of organelle organizationGO:00106391260.013
response to hypoxiaGO:0001666960.013
photoreceptor cell differentiationGO:004653020.013
negative regulation of synaptic transmissionGO:005080520.012

RCAN1 disease predictions

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of cellular proliferationDOID:145661740.045
cancerDOID:1621670.045
disease of metabolismDOID:00146672950.043
musculoskeletal system diseaseDOID:172230.035
organ system cancerDOID:00506861640.034
inherited metabolic disorderDOID:6552420.028
central nervous system diseaseDOID:3311860.023
nervous system diseaseDOID:8634310.023
sensory system diseaseDOID:00501552030.022
connective tissue diseaseDOID:651090.019
bone diseaseDOID:0080001880.019
eye diseaseDOID:56141490.018
eye and adnexa diseaseDOID:14921500.018
immune system diseaseDOID:29141550.016
cardiovascular system diseaseDOID:12871060.015
neurodegenerative diseaseDOID:12891020.015
muscular diseaseDOID:00800001140.014
muscle tissue diseaseDOID:661130.014