Homo sapiens

0 known processes

HIC2

hypermethylated in cancer 2

(Aliases: ZBTB30,ZNF907,HRG22,KIAA1020)

HIC2 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
intrinsic apoptotic signaling pathwayGO:00971931270.255
Human
regulation of response to dna damage stimulusGO:2001020940.142
dna damage response signal transduction by p53 class mediatorGO:0030330440.131
apoptotic signaling pathwayGO:00971902680.127
Human
negative regulation of transcription from rna polymerase ii promoterGO:00001222810.114
Human
chromatin organizationGO:00063253510.112
chromatin modificationGO:00165682980.109
positive regulation of response to dna damage stimulusGO:2001022430.108
signal transduction in response to dna damageGO:0042770570.105
regulation of cellular response to stressGO:00801352440.103
regulation of wnt signaling pathwayGO:00301111230.088
Human
cellular ketone metabolic processGO:0042180800.088
regulation of cell differentiationGO:00455953930.085
regulation of cellular ketone metabolic processGO:0010565500.082
regulation of cellular amino acid metabolic processGO:000652160.081
post embryonic developmentGO:000979120.076
amine metabolic processGO:0009308440.076
covalent chromatin modificationGO:00165692540.071
cellular amine metabolic processGO:0044106410.070
positive regulation of signal transduction by p53 class mediatorGO:1901798100.066
cell developmentGO:00484683280.064
signal transduction by p53 class mediatorGO:0072331720.063
regulation of signal transduction by p53 class mediatorGO:1901796260.063
regulation of cellular amine metabolic processGO:0033238110.062
regulation of dna damage response signal transduction by p53 class mediatorGO:0043516200.057
embryonic epithelial tube formationGO:000183840.056
histone modificationGO:00165702510.055
cellular amino acid metabolic processGO:00065201160.054
cellular component morphogenesisGO:00329893140.051
negative regulation of cell deathGO:00605483450.049
positive regulation of cellular component organizationGO:00511303760.049
regulation of cell motilityGO:20001452990.049
negative regulation of programmed cell deathGO:00430693210.049
regulation of proteolysisGO:00301622930.045
female gamete generationGO:000729220.045
mitotic cell cycleGO:00002783260.045
organ morphogenesisGO:00098871470.045
cell morphogenesisGO:00009022960.043
negative regulation of apoptotic processGO:00430663160.043
anatomical structure formation involved in morphogenesisGO:00486462840.042
positive regulation of dna damage response signal transduction by p53 class mediatorGO:004351780.041
epithelium developmentGO:00604292270.041
oogenesisGO:004847720.040
negative regulation of developmental processGO:00510932470.040
regulation of locomotionGO:00400123290.040
morphogenesis of embryonic epitheliumGO:001633140.038
negative regulation of cell cycleGO:00457861930.038
hematopoietic or lymphoid organ developmentGO:00485341860.036
mitotic cell cycle processGO:19030472860.036
biological adhesionGO:00226103310.035
tube developmentGO:00352951250.035
neurogenesisGO:00220081690.035
regulation of cell migrationGO:00303342890.034
multicellular organismal agingGO:001025930.034
response to oxygen containing compoundGO:19017003690.033
protein ubiquitinationGO:00165673140.033
positive regulation of cellular amine metabolic processGO:003324070.032
canonical wnt signaling pathwayGO:00600701160.032
cellular macromolecule catabolic processGO:00442653800.032
lipid metabolic processGO:00066293810.032
nerve developmentGO:002167540.031
determination of adult lifespanGO:000834020.031
protein acylationGO:00435431380.031
regulation of establishment of protein localizationGO:00702012420.031
cell adhesionGO:00071553250.030
regulation of cell growthGO:00015581350.030
purine ribonucleoside triphosphate catabolic processGO:00092073910.030
cellular response to dna damage stimulusGO:00069743790.030
Human
purine ribonucleoside metabolic processGO:00461284370.029
organ formationGO:004864530.029
negative regulation of cell differentiationGO:00455961710.029
cell projection organizationGO:00300302520.029
tube morphogenesisGO:0035239950.029
cellular response to oxygen containing compoundGO:19017012760.029
signal transduction by phosphorylationGO:00230142970.029
neuromuscular junction developmentGO:000752830.029
single organism membrane organizationGO:00448022680.029
negative regulation of cellular component organizationGO:00511292350.028
single organism cellular localizationGO:19025803320.028
wnt signaling pathwayGO:00160551560.028
Human
positive regulation of cell proliferationGO:00082843010.028
protein catabolic processGO:00301633250.028
organophosphate catabolic processGO:00464344300.028
cell growthGO:00160491600.028
purine nucleotide catabolic processGO:00061954050.027
glycosyl compound catabolic processGO:19016584130.027
purine ribonucleoside triphosphate metabolic processGO:00092054110.027
regulation of cellular component movementGO:00512703340.027
ribonucleoside triphosphate metabolic processGO:00091994120.027
regulation of mitotic cell cycleGO:00073461890.027
response to growth factorGO:00708482050.027
regulation of anatomical structure morphogenesisGO:00226032860.027
positive regulation of locomotionGO:00400171860.027
protein modification by small protein conjugationGO:00324463420.027
positive regulation of cellular amino acid metabolic processGO:004576430.026
locomotory behaviorGO:000762610.026
neuron differentiationGO:00301821380.026
protein maturationGO:00516042330.026
cellular response to endogenous stimulusGO:00714953360.026
nervous system developmentGO:00073992930.026
cellular protein catabolic processGO:00442572610.026
regulation of protein transportGO:00512232130.026
mesodermal cell fate commitmentGO:000171020.026
negative regulation of cellular amino acid metabolic processGO:004576320.026
rho protein signal transductionGO:0007266260.026
positive regulation of cell differentiationGO:00455972110.026
nucleoside triphosphate metabolic processGO:00091414220.026
enzyme linked receptor protein signaling pathwayGO:00071673030.025
cardiovascular system developmentGO:00723582620.025
nucleoside triphosphate catabolic processGO:00091433940.025
response to abiotic stimulusGO:00096283360.025
nucleoside catabolic processGO:00091644080.025
regulation of peptidase activityGO:00525471800.025
nucleoside phosphate catabolic processGO:19012924120.025
rna processingGO:00063962550.025
regulation of apoptotic signaling pathwayGO:20012331750.024
peptidyl lysine acetylationGO:00183941010.024
histone acetylationGO:0016573930.024
purine containing compound catabolic processGO:00725234110.024
intracellular protein transportGO:00068862700.024
regenerationGO:003109940.024
negative regulation of catalytic activityGO:00430863350.024
hindbrain developmentGO:003090230.023
cellular response to growth factor stimulusGO:00713631970.023
positive regulation of cellular component movementGO:00512721810.023
regulation of response to external stimulusGO:00321012220.023
purine ribonucleoside catabolic processGO:00461303980.023
cellular lipid metabolic processGO:00442553030.022
nucleotide catabolic processGO:00091664080.022
oxidation reduction processGO:00551143960.022
immune responseGO:00069553070.022
peptidyl lysine modificationGO:00182051440.022
proteasomal protein catabolic processGO:00104981760.022
secretion by cellGO:00329402260.022
chemotaxisGO:00069351570.022
vasculature developmentGO:00019441810.022
epithelial cell proliferationGO:00506731280.022
purine nucleoside triphosphate metabolic processGO:00091444120.022
regulation of protein kinase activityGO:00458592890.022
positive regulation of transportGO:00510503360.021
regulation of growthGO:00400081650.021
primary neural tube formationGO:001402030.021
proteolysis involved in cellular protein catabolic processGO:00516032440.021
cell cycle phase transitionGO:00447701730.021
central nervous system developmentGO:00074171230.020
actin filament based processGO:00300292240.020
rna splicingGO:00083801310.020
membrane organizationGO:00610242920.020
oocyte developmentGO:004859910.020
neural tube formationGO:000184130.019
proteasome mediated ubiquitin dependent protein catabolic processGO:00431611560.019
ubiquitin dependent protein catabolic processGO:00065112060.019
dephosphorylationGO:00163112090.019
regulation of cell morphogenesisGO:00226041530.019
actin cytoskeleton organizationGO:00300362070.019
modification dependent protein catabolic processGO:00199412090.019
peripheral nervous system developmentGO:000742220.019
ossificationGO:00015031210.019
regulation of cell divisionGO:00513021160.019
gtp catabolic processGO:00061842370.019
neural crest cell developmentGO:001403230.019
regulation of nucleotide catabolic processGO:00308112050.019
cell morphogenesis involved in differentiationGO:00009041440.019
oocyte differentiationGO:000999420.019
tripartite regional subdivisionGO:000735120.019
regulation of chromosome organizationGO:00330441030.019
cell part morphogenesisGO:00329901370.019
response to cytokineGO:00340972320.018
protein localization to nucleusGO:00345041360.018
regulation of purine nucleotide metabolic processGO:19005422640.018
viral processGO:00160321460.018
positive regulation of mapk cascadeGO:00434101900.018
regulation of canonical wnt signaling pathwayGO:0060828880.018
protein targetingGO:00066051870.018
negative regulation of protein metabolic processGO:00512483910.018
regulation of cell adhesionGO:00301551660.018
regulation of nucleoside metabolic processGO:00091182090.018
pituitary gland developmentGO:002198320.018
ribonucleoside triphosphate catabolic processGO:00092033910.018
regulation of stem cell differentiationGO:2000736560.018
embryo developmentGO:00097901230.018
cellular response to cytokine stimulusGO:00713451810.018
cell projection morphogenesisGO:00488581290.018
negative regulation of growthGO:0045926970.018
guanosine containing compound metabolic processGO:19010682440.018
response to lipidGO:00339932060.018
interspecies interaction between organismsGO:00444191560.018
ribonucleotide catabolic processGO:00092614050.018
epithelial cell differentiationGO:00308551410.018
embryonic morphogenesisGO:0048598850.018
ras protein signal transductionGO:0007265730.018
myeloid cell differentiationGO:00300991170.018
endodermal cell fate commitmentGO:000171140.018
embryonic camera type eye formationGO:006090020.017
compound eye developmentGO:004874910.017
reactive oxygen species metabolic processGO:0072593750.017
small gtpase mediated signal transductionGO:0007264780.017
anterior posterior axis specification embryoGO:000859520.017
carbohydrate derivative biosynthetic processGO:19011372070.017
mapk cascadeGO:00001652880.017
cranial nerve developmentGO:002154540.017
extrinsic apoptotic signaling pathwayGO:00971911190.017
negative regulation of phosphate metabolic processGO:00459362670.017
positive regulation of kinase activityGO:00336742040.017
regulation of transferase activityGO:00513383550.017
spermatid differentiationGO:004851540.017
embryonic camera type eye developmentGO:003107620.017
regulation of ossificationGO:0030278580.017
nuclear transportGO:00511691790.017
positive regulation of hydrolase activityGO:00513453310.017
establishment of protein localization to organelleGO:00725941720.017
stem cell developmentGO:0048864690.016
posttranscriptional regulation of gene expressionGO:00106082130.016
inner ear morphogenesisGO:004247240.016
mitotic cell cycle phase transitionGO:00447721620.016
regulation of reactive oxygen species metabolic processGO:2000377410.016
neurological system processGO:00508771630.016
chromatin assembly or disassemblyGO:0006333780.016
single organismal cell cell adhesionGO:00163371480.016
histone h3 acetylationGO:0043966450.016
regulation of intracellular protein transportGO:00331571230.016
single organism carbohydrate metabolic processGO:00447231930.016
cell divisionGO:00513011680.016
gtp metabolic processGO:00460392390.016
positive regulation of immune system processGO:00026842830.016
modification dependent macromolecule catabolic processGO:00436322120.016
regulation of purine nucleotide catabolic processGO:00331212050.016
cellular macromolecular complex assemblyGO:00346223240.016
regulation of myeloid cell differentiationGO:0045637810.016
ion transmembrane transportGO:00342203380.016
negative regulation of organelle organizationGO:00106391260.016
negative regulation of phosphorus metabolic processGO:00105632670.016
neuroblast proliferationGO:000740540.016
purine nucleoside catabolic processGO:00061523980.016
regulation of protein maturationGO:19033171500.016
spermatid developmentGO:000728640.016
positive regulation of organelle organizationGO:00106381950.016
muscle cell differentiationGO:0042692630.016
multi organism cellular processGO:00447641560.016
system processGO:00030083490.015
protein localization to organelleGO:00333652800.015
regulation of epithelial cell proliferationGO:00506781130.015
regulation of protein catabolic processGO:00421761550.015
cellular response to external stimulusGO:00714961110.015
negative regulation of protein phosphorylationGO:00019331400.015
ribonucleoside catabolic processGO:00424544060.015
regulation of cellular component biogenesisGO:00440872810.015
cellular protein complex assemblyGO:00436231880.015
transmembrane transportGO:00550853990.015
negative regulation of mitotic cell cycleGO:00459301020.015
regulation of kinase activityGO:00435493140.015
regulation of cysteine type endopeptidase activity involved in apoptotic processGO:00432811160.015
microtubule cytoskeleton organizationGO:00002261760.015
negative regulation of protein maturationGO:19033181420.015
guanosine containing compound catabolic processGO:19010692390.015
purine ribonucleotide catabolic processGO:00091544040.015
negative regulation of protein processingGO:00109551420.015
positive regulation of proteolysisGO:00458621420.015
mrna metabolic processGO:00160711750.015
embryonic camera type eye morphogenesisGO:004859620.015
mesenchymal cell developmentGO:0014031500.015
nuclear importGO:00511701060.015
positive regulation of cellular catabolic processGO:00313312840.015
establishment or maintenance of bipolar cell polarityGO:006124520.015
epithelium migrationGO:00901321190.015
purine nucleoside triphosphate catabolic processGO:00091463920.015
regulation of bindingGO:00510981110.015
sulfur compound metabolic processGO:00067901010.015
regulation of cell cycle phase transitionGO:19019871260.014
stem cell differentiationGO:0048863930.014
negative regulation of cellular component movementGO:00512711060.014
cell activationGO:00017752130.014
regulation of cytoplasmic transportGO:19036491490.014
positive regulation of cell cycleGO:00457871400.014
single organism reproductive processGO:0044702980.014
protein importGO:00170381300.014
cerebellum developmentGO:002154920.014
negative regulation of transportGO:00510511760.014
regulation of cytoskeleton organizationGO:00514931770.014
glycoprotein metabolic processGO:00091001100.014
small molecule biosynthetic processGO:00442831570.014
negative regulation of catabolic processGO:00098951040.014
tissue morphogenesisGO:0048729960.014
mesenchymal cell differentiationGO:0048762520.014
regulation of neurogenesisGO:0050767820.014
symbiosis encompassing mutualism through parasitismGO:00444031560.014
regulation of multi organism processGO:00439001570.014
memoryGO:000761330.014
organelle assemblyGO:00709251760.014
cell cycle g1 s phase transitionGO:0044843800.014
regulation of homeostatic processGO:00328441210.014
angiogenesisGO:00015251470.014
response to organic cyclic compoundGO:00140702040.014
positive regulation of sequence specific dna binding transcription factor activityGO:00510911310.014
regulation of immune responseGO:00507762010.014
generation of neuronsGO:00486991520.014
transmembrane receptor protein serine threonine kinase signaling pathwayGO:00071781250.014
positive regulation of cell morphogenesis involved in differentiationGO:0010770500.014
regulation of cell cycle processGO:00105642660.014
regulation of ras protein signal transductionGO:00465781550.014
negative regulation of immune system processGO:00026831360.014
microtubule based processGO:00070172100.014
anterior posterior axis specificationGO:000994820.013
regulation of cellular response to growth factor stimulusGO:0090287760.013
mitochondrion organizationGO:00070051560.013
cell cell signalingGO:00072671550.013
positive regulation of catabolic processGO:00098963100.013
t cell differentiation in thymusGO:003307740.013
innate immune responseGO:00450871780.013
regulation of ras gtpase activityGO:00323181280.013
negative regulation of hydrolase activityGO:00513461820.013
associative learningGO:000830610.013
cellular response to transforming growth factor beta stimulusGO:0071560940.013
regulation of cell cycleGO:00517263930.013
rhythmic behaviorGO:000762220.013
neurotransmitter secretionGO:000726940.013
establishment of planar polarityGO:000173630.013
positive regulation of purine nucleotide metabolic processGO:19005442270.013
response to external biotic stimulusGO:00432072610.013
negative regulation of wnt signaling pathwayGO:0030178690.013
Human
positive regulation of gtpase activityGO:00435471660.013
chemical homeostasisGO:00488783060.013
negative regulation of cell cycle processGO:00109481210.013
positive regulation of nucleotide metabolic processGO:00459812300.013
negative regulation of cellular protein metabolic processGO:00322693530.013
establishment or maintenance of apical basal cell polarityGO:003508820.013
motor neuron axon guidanceGO:000804520.013
regulation of membrane potentialGO:0042391950.013
negative regulation of canonical wnt signaling pathwayGO:0090090550.013
response to nutrient levelsGO:0031667810.013
protein polyubiquitinationGO:00002091100.013
circadian behaviorGO:004851220.012
response to other organismGO:00517072610.012
vesicle mediated transportGO:00161923710.012
regulation of mapk cascadeGO:00434082620.012
regulation of viral processGO:00507921030.012
regulation of gtpase activityGO:00430871800.012
cellular response to nitrogen compoundGO:19016991440.012
blastoderm segmentationGO:000735020.012
syncytium formation by plasma membrane fusionGO:000076820.012
negative regulation of phosphorylationGO:00423261740.012
thymus developmentGO:004853830.012
cellular response to starvationGO:0009267580.012
myosin filament assemblyGO:003103420.012
negative regulation of transferase activityGO:00513481240.012
regulation of protein serine threonine kinase activityGO:00719001790.012
regulation of i kappab kinase nf kappab signalingGO:00431221620.012
cardiac muscle cell contractionGO:008600340.012
striated muscle myosin thick filament assemblyGO:007168820.012
sulfur compound biosynthetic processGO:0044272380.012
response to axon injuryGO:004867810.012
negative regulation of intracellular signal transductionGO:19025321830.012
protein import into nucleusGO:00066061040.012
adult locomotory behaviorGO:000834410.012
response to transforming growth factor betaGO:0071559940.012
response to nitrogen compoundGO:19016981840.012
carbohydrate metabolic processGO:00059752070.012
response to extracellular stimulusGO:0009991850.012
defense responseGO:00069523150.012
cation transportGO:00068123310.012
intracellular receptor signaling pathwayGO:00305221040.012
endodermal cell fate specificationGO:000171440.012
reactive oxygen species biosynthetic processGO:190340940.012
endocytosisGO:00068971590.012
negative regulation of cellular response to growth factor stimulusGO:0090288410.012
stem cell divisionGO:001714520.012
regulation of neurotransmitter secretionGO:004692830.012
forebrain generation of neuronsGO:002187230.012
cellular component disassemblyGO:0022411920.012
cellular response to extracellular stimulusGO:0031668720.012
regulation of gene expression epigeneticGO:0040029730.012
negative regulation of multicellular organismal processGO:00512413170.011
regulation of nervous system developmentGO:0051960880.011
response to fungusGO:000962040.011
regulation of hormone levelsGO:00108171250.011
rna interferenceGO:001624640.011
organonitrogen compound biosynthetic processGO:19015662000.011
negative regulation of cellular catabolic processGO:0031330830.011
regulation of lipid metabolic processGO:0019216960.011
regulation of extrinsic apoptotic signaling pathwayGO:2001236850.011
muscle tissue developmentGO:0060537620.011
positive regulation of secretionGO:00510471160.011
regulation of cytokine productionGO:00018172320.011
cell cycle checkpointGO:00000751170.011
regulation of axon guidanceGO:190266730.011
viral life cycleGO:00190581320.011
maintenance of locationGO:00512351120.011
epidermis morphogenesisGO:004873030.011
cytoplasmic transportGO:00164823790.011
morphogenesis of an epitheliumGO:0002009600.011
epithelial cell migrationGO:00106311190.011
myosin filament organizationGO:003103320.011
protein alkylationGO:0008213740.011
neuron remodelingGO:001632220.011
negative regulation of kinase activityGO:00336731060.011
startle responseGO:000196430.011
peptidyl serine modificationGO:00182091060.011
positive regulation of purine nucleotide catabolic processGO:00331231850.011
methylationGO:00322591060.011
positive regulation of cysteine type endopeptidase activityGO:2001056790.011
cell projection assemblyGO:00300311260.011
engulfment of apoptotic cellGO:004365220.011
regulation of protein localizationGO:00328802960.011
muscle structure developmentGO:0061061980.011
organic hydroxy compound metabolic processGO:19016151470.011
retinal ganglion cell axon guidanceGO:003129020.011
positive regulation of synaptic transmissionGO:005080640.011
developmental programmed cell deathGO:001062330.011
organelle fissionGO:00482851490.011
bone mineralizationGO:0030282340.011
regulation of dephosphorylationGO:0035303960.011
regulation of protein stabilityGO:0031647870.011
protein localization to membraneGO:00726571600.011
segmentationGO:003528240.011
somitogenesisGO:000175620.011
dna repairGO:00062811980.011
response to radiationGO:00093141510.010
neural tube closureGO:000184330.010
anion transportGO:00068201610.010
striated muscle tissue developmentGO:0014706590.010
mitotic nuclear divisionGO:00070671190.010
regulation of cell projection organizationGO:00313441070.010
neuron projection regenerationGO:003110210.010
negative regulation of gliogenesisGO:001401430.010
photoreceptor cell differentiationGO:004653020.010
positive regulation of nucleotide catabolic processGO:00308131850.010
positive regulation of nucleoside metabolic processGO:00459791860.010
meiotic chromosome segregationGO:004513240.010
negative regulation of protein kinase activityGO:0006469980.010
neuron fate commitmentGO:004866320.010
macromolecule methylationGO:0043414970.010
cellular carbohydrate metabolic processGO:0044262840.010
carboxylic acid biosynthetic processGO:0046394970.010
monosaccharide metabolic processGO:0005996740.010
transforming growth factor beta receptor signaling pathwayGO:0007179760.010
nucleoside monophosphate metabolic processGO:00091231910.010
regulation of translationGO:0006417890.010
visual behaviorGO:000763220.010
morphogenesis of a polarized epitheliumGO:000173830.010
regulation of protein complex assemblyGO:00432541470.010
regulation of male gonad developmentGO:200001840.010
release of cytoplasmic sequestered nf kappabGO:000858840.010
endomembrane system organizationGO:00102561960.010

HIC2 disease predictions

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of metabolismDOID:00146672950.025
nervous system diseaseDOID:8634310.021
central nervous system diseaseDOID:3311860.021
disease of cellular proliferationDOID:145661740.018
cancerDOID:1621670.018
musculoskeletal system diseaseDOID:172230.016
organ system cancerDOID:00506861640.016
connective tissue diseaseDOID:651090.014
cardiovascular system diseaseDOID:12871060.011
inherited metabolic disorderDOID:6552420.011