Homo sapiens

0 known processes

PSMD2

proteasome (prosome, macropain) 26S subunit, non-ATPase, 2

(Aliases: Rpn1,TRAP2,MGC14274,S2,P97)

PSMD2 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
rna polymerase ii transcriptional preinitiation complex assemblyGO:005112340.999
proteasome regulatory particle assemblyGO:007068220.998
cellular response to dna damage stimulusGO:00069743790.995
regulation of proteasomal ubiquitin dependent protein catabolic processGO:0032434710.966
positive regulation of transcription initiation from rna polymerase ii promoterGO:006026140.965
determination of adult lifespanGO:000834020.940
Worm
modification dependent protein catabolic processGO:00199412090.940
nucleotide excision repairGO:0006289310.932
regulation of rna polymerase ii transcriptional preinitiation complex assemblyGO:004589830.928
multicellular organismal agingGO:001025930.915
Worm
purine nucleoside monophosphate catabolic processGO:00091281580.913
dna templated transcription initiationGO:0006352350.908
proteolysis involved in cellular protein catabolic processGO:00516032440.892
ubiquitin dependent protein catabolic processGO:00065112060.873
er associated ubiquitin dependent protein catabolic processGO:0030433310.868
cellular protein catabolic processGO:00442572610.866
positive regulation of protein phosphorylationGO:00019343130.865
cellular macromolecular complex assemblyGO:00346223240.857
negative regulation of sequence specific dna binding transcription factor activityGO:0043433890.841
proteasomal protein catabolic processGO:00104981760.830
protein dna complex assemblyGO:0065004640.830
protein dna complex subunit organizationGO:0071824800.821
mitotic spindle elongationGO:000002240.817
Fly
proteasome assemblyGO:004324870.816
regulation of i kappab kinase nf kappab signalingGO:00431221620.796
proteasome mediated ubiquitin dependent protein catabolic processGO:00431611560.788
purine ribonucleoside triphosphate catabolic processGO:00092073910.784
spindle elongationGO:005123140.783
Fly
transcription initiation from rna polymerase ii promoterGO:0006367270.780
modification dependent macromolecule catabolic processGO:00436322120.771
atp catabolic processGO:00062001570.740
blastocyst developmentGO:000182430.735
purine ribonucleoside monophosphate catabolic processGO:00091691580.727
regulation of proteasomal protein catabolic processGO:0061136870.727
post embryonic developmentGO:000979120.719
Worm
positive regulation of peptidase activityGO:0010952880.651
regulation of dna templated transcription initiationGO:200014290.616
atp metabolic processGO:00460341760.591
nucleoside monophosphate catabolic processGO:00091251590.589
microtubule cytoskeleton organizationGO:00002261760.587
Fly
protein catabolic processGO:00301633250.572
nucleoside triphosphate catabolic processGO:00091433940.569
metaphase anaphase transition of cell cycleGO:0044784210.566
i kappab kinase nf kappab signalingGO:00072491660.565
regulation of peptidase activityGO:00525471800.547
regulation of proteolysis involved in cellular protein catabolic processGO:1903050910.531
positive regulation of protein complex assemblyGO:0031334860.525
regulation of sequence specific dna binding transcription factor activityGO:00510902110.495
positive regulation of endopeptidase activityGO:0010950840.483
regulation of cellular protein catabolic processGO:1903362960.477
cellular protein complex assemblyGO:00436231880.477
nucleoside catabolic processGO:00091644080.464
regulation of protein complex assemblyGO:00432541470.461
dna templated transcriptional preinitiation complex assemblyGO:007089750.460
dna templated transcription elongationGO:0006354250.455
regulation of proteolysisGO:00301622930.452
rna catabolic processGO:0006401710.442
positive regulation of transcription elongation from rna polymerase ii promoterGO:0032968100.427
chromatin organizationGO:00063253510.412
protein deubiquitinationGO:0016579790.382
regulation of sister chromatid segregationGO:0033045270.376
signal transduction in response to dna damageGO:0042770570.354
nucleoside phosphate catabolic processGO:19012924120.351
ribonucleoside catabolic processGO:00424544060.350
mitotic sister chromatid segregationGO:0000070530.344
purine ribonucleotide catabolic processGO:00091544040.343
nervous system developmentGO:00073992930.341
metaphase anaphase transition of mitotic cell cycleGO:0007091210.330
protein deglycosylationGO:000651720.321
positive regulation of cellular protein catabolic processGO:1903364370.316
ribonucleoside triphosphate catabolic processGO:00092033910.293
regulation of mitotic cell cycleGO:00073461890.284
dna repairGO:00062811980.277
regulation of transcription initiation from rna polymerase ii promoterGO:006026080.276
positive regulation of protein kinase activityGO:00458601900.267
anaphase promoting complex dependent proteasomal ubiquitin dependent protein catabolic processGO:0031145250.262
agingGO:0007568660.262
Worm
purine nucleoside catabolic processGO:00061523980.258
ribonucleoside monophosphate catabolic processGO:00091581580.255
regulation of mitotic sister chromatid separationGO:0010965270.252
regulation of endopeptidase activityGO:00525481700.251
regulation of cell cycleGO:00517263930.249
negative regulation of peptidase activityGO:0010466910.243
sister chromatid segregationGO:0000819540.243
purine nucleoside triphosphate catabolic processGO:00091463920.237
purine nucleotide catabolic processGO:00061954050.230
mitotic cell cycleGO:00002783260.229
Fly
glycosyl compound catabolic processGO:19016584130.223
cell divisionGO:00513011680.222
secretion by cellGO:00329402260.222
purine ribonucleoside metabolic processGO:00461284370.216
positive regulation of dna templated transcription elongationGO:0032786180.216
negative regulation of endopeptidase activityGO:0010951840.207
nucleoside monophosphate metabolic processGO:00091231910.204
oogenesisGO:004847720.203
regulation of chromosome segregationGO:0051983440.200
mitotic cell cycle processGO:19030472860.197
Fly
regulation of cellular component biogenesisGO:00440872810.196
ribonucleoside triphosphate metabolic processGO:00091994120.186
rna interferenceGO:001624640.186
positive regulation of kinase activityGO:00336742040.181
ribonucleoside monophosphate metabolic processGO:00091611870.180
ribonucleotide catabolic processGO:00092614050.179
nucleoside triphosphate metabolic processGO:00091414220.175
organelle fissionGO:00482851490.171
positive regulation of proteasomal ubiquitin dependent protein catabolic processGO:0032436300.166
inclusion body assemblyGO:0070841170.163
purine containing compound catabolic processGO:00725234110.160
regulation of protein catabolic processGO:00421761550.158
myeloid dendritic cell differentiationGO:004301130.156
chromatin modificationGO:00165682980.156
purine ribonucleoside catabolic processGO:00461303980.156
ovarian follicle developmentGO:000154150.155
regulation of cell divisionGO:00513021160.153
chromosome separationGO:0051304230.150
positive regulation of phosphorylationGO:00423273940.150
positive regulation of cellular catabolic processGO:00313312840.149
cellular macromolecule catabolic processGO:00442653800.147
protein modification by small protein conjugationGO:00324463420.146
purine nucleoside triphosphate metabolic processGO:00091444120.144
regulation of cyclin dependent protein serine threonine kinase activityGO:0000079360.142
positive regulation of sequence specific dna binding transcription factor activityGO:00510911310.140
nucleotide catabolic processGO:00091664080.137
maintenance of protein location in cellGO:0032507560.133
double strand break repair via nonhomologous end joiningGO:0006303100.131
proteasomal ubiquitin independent protein catabolic processGO:001049930.126
regulation of protein ubiquitinationGO:0031396950.123
positive regulation of protein catabolic processGO:0045732750.122
leukocyte differentiationGO:0002521980.122
regulation of protein modification by small protein conjugation or removalGO:19033201070.121
spermatid differentiationGO:004851540.118
ovulation cycle processGO:002260290.118
regulation of dna templated transcription elongationGO:0032784230.116
cellular response to oxygen levelsGO:0071453550.115
negative regulation of i kappab kinase nf kappab signalingGO:0043124320.114
immune system developmentGO:00025201950.113
mitochondrion organizationGO:00070051560.112
positive regulation of proteasomal protein catabolic processGO:1901800350.110
regulation of nuclear divisionGO:0051783650.110
non recombinational repairGO:0000726140.109
female gamete generationGO:000729220.106
negative regulation of proteolysisGO:00458611320.105
negative regulation of nf kappab transcription factor activityGO:0032088510.097
response to organonitrogen compoundGO:00102431560.096
spermatid developmentGO:000728640.096
positive regulation of proteolysisGO:00458621420.096
mitotic cell cycle phase transitionGO:00447721620.095
signal transduction by p53 class mediatorGO:0072331720.094
regulation of cell cycle processGO:00105642660.092
lymphocyte activationGO:00466491330.089
positive regulation of cellular component organizationGO:00511303760.088
maintenance of locationGO:00512351120.087
regulation of cell growthGO:00015581350.085
hemopoiesisGO:00300971800.084
regulation of transferase activityGO:00513383550.083
regulation of apoptotic signaling pathwayGO:20012331750.082
regulation of mitotic sister chromatid segregationGO:0033047270.080
positive regulation of proteolysis involved in cellular protein catabolic processGO:1903052350.079
midbrain developmentGO:0030901450.079
positive regulation of protein serine threonine kinase activityGO:00719021190.078
response to oxygen containing compoundGO:19017003690.074
signal transduction by phosphorylationGO:00230142970.071
nuclear divisionGO:00002801280.070
regulation of kinase activityGO:00435493140.069
purine nucleoside monophosphate metabolic processGO:00091261860.068
negative regulation of organelle organizationGO:00106391260.068
apoptotic mitochondrial changesGO:0008637570.066
chromatin remodelingGO:0006338550.066
immunoglobulin secretionGO:004830510.064
negative regulation of phosphate metabolic processGO:00459362670.062
positive regulation of cellular component biogenesisGO:00440891580.061
gene silencing by rnaGO:0031047260.058
mitotic nuclear divisionGO:00070671190.057
chromosome segregationGO:00070591140.056
cell activationGO:00017752130.055
protein localization to organelleGO:00333652800.055
regulation of nf kappab import into nucleusGO:0042345220.054
negative regulation of transportGO:00510511760.053
brain morphogenesisGO:004885410.053
apoptotic signaling pathwayGO:00971902680.053
cell cycle phase transitionGO:00447701730.050
regulation of response to dna damage stimulusGO:2001020940.050
response to abiotic stimulusGO:00096283360.050
regulation of lipopolysaccharide mediated signaling pathwayGO:0031664130.049
negative regulation of protein metabolic processGO:00512483910.049
negative regulation of phosphorylationGO:00423261740.049
maintenance of location in cellGO:0051651620.047
regulation of chromosome organizationGO:00330441030.047
protein ubiquitinationGO:00165673140.047
positive regulation of dna templated transcription initiationGO:200014450.046
regulation of immunoglobulin secretionGO:005102310.045
negative regulation of protein processingGO:00109551420.044
regulation of t cell activationGO:0050863770.044
regulation of gene expression epigeneticGO:0040029730.044
regulation of cell differentiationGO:00455953930.043
mitotic sister chromatid separationGO:0051306180.042
regulation of mapk cascadeGO:00434082620.042
regulation of protein kinase activityGO:00458592890.040
monoubiquitinated histone deubiquitinationGO:003552130.040
negative regulation of cell deathGO:00605483450.040
positive regulation of i kappab kinase nf kappab signalingGO:00431231320.040
positive regulation of cell cycleGO:00457871400.039
negative regulation of phosphorus metabolic processGO:00105632670.038
cell growthGO:00160491600.038
regulation of release of cytochrome c from mitochondriaGO:0090199290.037
protein secretionGO:0009306980.037
response to cytokineGO:00340972320.037
meiosis iGO:000712740.035
negative regulation of intracellular signal transductionGO:19025321830.034
thymus developmentGO:004853830.034
purine ribonucleoside triphosphate metabolic processGO:00092054110.034
regulation of t cell differentiation in thymusGO:003308120.033
response to decreased oxygen levelsGO:0036293960.033
hematopoietic or lymphoid organ developmentGO:00485341860.033
regulation of protein localizationGO:00328802960.033
cellular response to cytokine stimulusGO:00713451810.033
amide transportGO:0042886760.032
cytoplasmic transportGO:00164823790.032
dna damage response signal transduction by p53 class mediatorGO:0030330440.032
regulation of protein serine threonine kinase activityGO:00719001790.032
regulation of protein transportGO:00512232130.031
negative regulation of cellular protein metabolic processGO:00322693530.031
taxisGO:00423301570.031
organelle assemblyGO:00709251760.031
mapk cascadeGO:00001652880.031
growthGO:00400072020.030
positive regulation of nf kappab transcription factor activityGO:0051092810.030
negative regulation of catalytic activityGO:00430863350.030
response to starvationGO:0042594590.029
response to nitrogen compoundGO:19016981840.029
head developmentGO:00603221080.028
release of cytochrome c from mitochondriaGO:0001836350.028
neurogenesisGO:00220081690.027
myeloid cell differentiationGO:00300991170.027
protein modification by small protein removalGO:0070646920.027
intracellular protein transportGO:00068862700.027
regulation of hormone levelsGO:00108171250.027
negative regulation of mapk cascadeGO:0043409560.027
negative regulation of apoptotic processGO:00430663160.026
negative regulation of nucleocytoplasmic transportGO:0046823370.026
embryo development ending in birth or egg hatchingGO:0009792340.025
Worm
nitrogen compound transportGO:00717051910.025
enzyme linked receptor protein signaling pathwayGO:00071673030.025
posttranscriptional gene silencingGO:0016441250.025
angiogenesisGO:00015251470.025
defense responseGO:00069523150.025
positive regulation of cell growthGO:0030307480.024
multicellular organism reproductionGO:0032504420.024
positive regulation of protein modification by small protein conjugation or removalGO:1903322610.024
protein k63 linked deubiquitinationGO:0070536210.024
embryo developmentGO:00097901230.024
Worm
regulation of nucleocytoplasmic transportGO:0046822980.024
regulation of protein maturationGO:19033171500.023
protein processingGO:00164852260.023
negative regulation of multicellular organismal processGO:00512413170.023
cellular response to hypoxiaGO:0071456510.023
negative regulation of intracellular protein transportGO:0090317420.023
regulation of protein import into nucleusGO:0042306780.023
protein localization to nucleusGO:00345041360.023
negative regulation of protein localization to nucleusGO:1900181340.023
cardiovascular system developmentGO:00723582620.022
cellular response to peptideGO:1901653590.022
regulation of cellular amino acid metabolic processGO:000652160.022
cytokine mediated signaling pathwayGO:00192211090.022
regulation of cell activationGO:00508651250.022
spindle assemblyGO:0051225290.022
blood vessel developmentGO:00015681720.022
leukocyte activationGO:00453211640.021
double strand break repairGO:00063021010.021
protein targetingGO:00066051870.021
g protein coupled receptor signaling pathwayGO:00071862070.021
negative regulation of protein modification processGO:00314002000.020
circulatory system developmentGO:00723592620.020
monoubiquitinated histone h2a deubiquitinationGO:003552230.020
cell cell signalingGO:00072671550.020
gene silencingGO:0016458490.020
cellular response to decreased oxygen levelsGO:0036294510.020
recombinational repairGO:0000725500.020
transmembrane receptor protein tyrosine kinase signaling pathwayGO:00071691810.020
single organism membrane organizationGO:00448022680.020
negative regulation of programmed cell deathGO:00430693210.019
chordate embryonic developmentGO:0043009340.019
negative regulation of protein import into nucleusGO:0042308300.019
epithelial cell differentiationGO:00308551410.018
protein maturationGO:00516042330.018
oocyte developmentGO:004859910.018
negative regulation of intracellular transportGO:0032387600.018
ovulation cycleGO:004269890.018
cellular response to extracellular stimulusGO:0031668720.018
microtubule based processGO:00070172100.018
Fly
nuclear transportGO:00511691790.018
positive regulation of protein ubiquitinationGO:0031398530.018
reproductionGO:0000003630.017
Worm
sensory organ developmentGO:0007423520.017
negative regulation of proteasomal protein catabolic processGO:1901799320.017
protein importGO:00170381300.017
adipose tissue developmentGO:006061220.017
negative regulation of protein maturationGO:19033181420.017
positive regulation of lipopolysaccharide mediated signaling pathwayGO:003166640.017
negative regulation of apoptotic signaling pathwayGO:2001234970.017
negative regulation of hydrolase activityGO:00513461820.017
transcription elongation from rna polymerase ii promoterGO:0006368180.017
purine ribonucleoside monophosphate metabolic processGO:00091671860.017
peripheral nervous system developmentGO:000742220.016
secretionGO:00469032540.016
macroautophagyGO:0016236390.016
regulation of vesicle mediated transportGO:00606271300.016
negative regulation of nf kappab import into nucleusGO:0042347120.016
negative regulation of transcription from rna polymerase ii promoterGO:00001222810.016
positive regulation of cyclin dependent protein serine threonine kinase activityGO:0045737150.016
regulation of exit from mitosisGO:000709660.016
dna geometric changeGO:0032392320.016
nf kappab import into nucleusGO:0042348220.016
peroxisome fissionGO:0016559100.015
response to peptide hormoneGO:0043434610.015
neuroblast proliferationGO:000740540.015
cellular response to oxygen containing compoundGO:19017012760.015
regulation of protein processingGO:00706131500.015
double strand break repair via homologous recombinationGO:0000724500.015
response to hypoxiaGO:0001666960.015
negative regulation of response to dna damage stimulusGO:2001021330.015
response to peptideGO:1901652650.015
regulation of vasculature developmentGO:1901342970.014
innate immune responseGO:00450871780.014
golgi vesicle transportGO:0048193800.014
regulation of protein targetingGO:1903533910.014
response to nutrient levelsGO:0031667810.014
regulation of cytoplasmic transportGO:19036491490.014
cellular response to external stimulusGO:00714961110.013
chemical homeostasisGO:00488783060.013
primary neural tube formationGO:001402030.013
negative regulation of cytoplasmic transportGO:1903650460.013
positive regulation of neural precursor cell proliferationGO:200017920.013
response to fungusGO:000962040.013
embryonic placenta developmentGO:000189210.013
positive regulation of hydrolase activityGO:00513453310.013
dna conformation changeGO:00711031130.013
protein localization to membraneGO:00726571600.012
positive regulation of catabolic processGO:00098963100.012
schwann cell differentiationGO:001403710.012
posttranscriptional regulation of gene expressionGO:00106082130.012
renal system developmentGO:0072001630.012
single organism cellular localizationGO:19025803320.012
blood vessel morphogenesisGO:00485141620.012
nucleocytoplasmic transportGO:00069131760.012
regulation of mitochondrion organizationGO:0010821540.012
ncrna metabolic processGO:00346601080.012
molting cycleGO:0042303280.012
regulation of peptide transportGO:0090087620.012
regulation of myeloid cell differentiationGO:0045637810.012
anatomical structure homeostasisGO:00602491000.012
chromatin assembly or disassemblyGO:0006333780.012
negative regulation of proteolysis involved in cellular protein catabolic processGO:1903051350.011
negative regulation of protein transportGO:0051224750.011
positive regulation of apoptotic processGO:00430652460.011
dephosphorylationGO:00163112090.011
negative regulation of signal transduction by p53 class mediatorGO:1901797150.011
microtubule organizing center organizationGO:0031023620.011
cellular response to starvationGO:0009267580.011
cellular response to nitrogen compoundGO:19016991440.011
organophosphate catabolic processGO:00464344300.011
rna splicing via transesterification reactionsGO:0000375900.011
regulation of anatomical structure morphogenesisGO:00226032860.010
regulation of cellular ketone metabolic processGO:0010565500.010
lens development in camera type eyeGO:000208820.010
positive regulation of cell cycle processGO:00900681060.010
rrna metabolic processGO:0016072400.010
neurological system processGO:00508771630.010
regulation of establishment of protein localizationGO:00702012420.010
endomembrane system organizationGO:00102561960.010
cellular response to growth hormone stimulusGO:0071378100.010

PSMD2 disease predictions

DiseaseDO term IDSizeProbabilityFunc Analog Org
neuropathyDOID:870520.025
neuromuscular diseaseDOID:440380.025
nervous system diseaseDOID:8634310.025
muscular diseaseDOID:00800001140.016
musculoskeletal system diseaseDOID:172230.016
charcot marie tooth disease type 4DOID:0050541110.013
charcot marie tooth diseaseDOID:10595330.013