Homo sapiens

18 known processes

EIF2S2

eukaryotic translation initiation factor 2, subunit 2 beta, 38kDa

(Aliases: EIF2beta,MGC8508,DKFZp686L18198,EIF2,EIF2B)

EIF2S2 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
regulation of translational initiation in response to stressGO:004355810.769
translationGO:00064121320.759
post embryonic developmentGO:000979120.510
Worm
trna aminoacylation for protein translationGO:000641880.414
formation of translation preinitiation complexGO:000173140.412
regulation of translationGO:0006417890.368
cellular amino acid metabolic processGO:00065201160.323
translational initiationGO:0006413480.284
cellular response to dna damage stimulusGO:00069743790.263
oocyte differentiationGO:000999420.234
amino acid activationGO:0043038120.193
negative regulation of apoptotic processGO:00430663160.182
positive regulation of sequence specific dna binding transcription factor activityGO:00510911310.168
ribonucleoprotein complex biogenesisGO:00226131160.168
protein autophosphorylationGO:00467771230.165
posttranscriptional regulation of gene expressionGO:00106082130.164
ncrna metabolic processGO:00346601080.161
negative regulation of cell deathGO:00605483450.152
oogenesisGO:004847720.122
negative regulation of cell proliferationGO:00082852280.119
mitotic nuclear divisionGO:00070671190.115
ribonucleoside triphosphate catabolic processGO:00092033910.113
ribonucleoprotein complex assemblyGO:0022618780.111
negative regulation of programmed cell deathGO:00430693210.103
positive regulation of cell proliferationGO:00082843010.100
oocyte developmentGO:004859910.097
vesicle mediated transportGO:00161923710.094
regulation of endopeptidase activityGO:00525481700.093
hematopoietic or lymphoid organ developmentGO:00485341860.091
response to organic cyclic compoundGO:00140702040.090
cellular response to endogenous stimulusGO:00714953360.090
cellular macromolecule catabolic processGO:00442653800.087
ribonucleoprotein complex subunit organizationGO:0071826810.087
regulation of cell differentiationGO:00455953930.086
regulation of translation in response to stressGO:004355530.084
female gamete generationGO:000729220.084
negative regulation of catalytic activityGO:00430863350.077
purine containing compound catabolic processGO:00725234110.077
nucleoside catabolic processGO:00091644080.071
regulation of cellular response to stressGO:00801352440.070
regulation of cell developmentGO:00602841610.070
hematopoietic stem cell differentiationGO:006021840.069
regulation of translational initiationGO:0006446240.069
signal transduction in response to dna damageGO:0042770570.068
organelle fissionGO:00482851490.066
regulation of sequence specific dna binding transcription factor activityGO:00510902110.066
atp metabolic processGO:00460341760.066
purine nucleoside triphosphate metabolic processGO:00091444120.064
matingGO:000761810.063
ribonucleoside catabolic processGO:00424544060.063
hemopoiesisGO:00300971800.062
nucleotide catabolic processGO:00091664080.061
negative regulation of protein maturationGO:19033181420.061
apoptotic signaling pathwayGO:00971902680.060
regulation of growthGO:00400081650.060
Worm
purine nucleoside catabolic processGO:00061523980.059
positive regulation of apoptotic processGO:00430652460.055
negative regulation of peptidase activityGO:0010466910.054
immune responseGO:00069553070.053
negative regulation of endopeptidase activityGO:0010951840.052
negative regulation of hydrolase activityGO:00513461820.052
innate immune responseGO:00450871780.052
dna repairGO:00062811980.050
immune effector processGO:00022521590.050
determination of adult lifespanGO:000834020.050
Worm
purine ribonucleoside triphosphate metabolic processGO:00092054110.049
positive regulation of catabolic processGO:00098963100.049
multicellular organismal agingGO:001025930.049
Worm
positive regulation of response to dna damage stimulusGO:2001022430.048
negative regulation of protein processingGO:00109551420.048
intracellular mrna localizationGO:000829810.046
negative regulation of proteolysisGO:00458611320.044
protein catabolic processGO:00301633250.044
protein processingGO:00164852260.043
regulation of dna metabolic processGO:00510521530.043
regulation of mitotic cell cycleGO:00073461890.042
ribosome biogenesisGO:0042254480.042
anterior posterior axis specificationGO:000994820.042
response to abiotic stimulusGO:00096283360.040
regulation of protein maturationGO:19033171500.040
negative regulation of cysteine type endopeptidase activity involved in apoptotic processGO:0043154460.039
mrna metabolic processGO:00160711750.039
regulation of proteolysisGO:00301622930.037
receptor mediated endocytosisGO:0006898840.037
nervous system developmentGO:00073992930.036
response to virusGO:00096151260.036
regulation of protein modification by small protein conjugation or removalGO:19033201070.035
glycosyl compound catabolic processGO:19016584130.035
regulation of cysteine type endopeptidase activityGO:20001161270.034
mitochondrion organizationGO:00070051560.034
regulation of response to dna damage stimulusGO:2001020940.034
negative regulation of protein metabolic processGO:00512483910.034
nucleoside phosphate biosynthetic processGO:19012931090.033
positive regulation of nf kappab transcription factor activityGO:0051092810.033
segmentationGO:003528240.033
purine ribonucleoside catabolic processGO:00461303980.032
regionalizationGO:0003002290.032
regulation of cell divisionGO:00513021160.031
regulation of multi organism processGO:00439001570.031
regulation of protein processingGO:00706131500.031
cellular macromolecular complex assemblyGO:00346223240.031
response to other organismGO:00517072610.030
ribonucleoside triphosphate metabolic processGO:00091994120.030
immune system developmentGO:00025201950.029
locomotory behaviorGO:000762610.029
regulation of cellular amine metabolic processGO:0033238110.029
positive regulation of stress activated protein kinase signaling cascadeGO:0070304610.029
ribonucleoside monophosphate metabolic processGO:00091611870.029
regulation of peptidase activityGO:00525471800.029
protein modification by small protein conjugationGO:00324463420.029
cell developmentGO:00484683280.029
cell divisionGO:00513011680.028
negative regulation of cysteine type endopeptidase activityGO:2000117480.028
regenerationGO:003109940.028
nucleoside triphosphate catabolic processGO:00091433940.028
positive regulation of transferase activityGO:00513472270.027
negative regulation of protein modification processGO:00314002000.027
guanosine containing compound catabolic processGO:19010692390.027
gtp catabolic processGO:00061842370.027
cytoplasmic transportGO:00164823790.027
negative regulation of cellular protein metabolic processGO:00322693530.027
nucleoside phosphate catabolic processGO:19012924120.025
cellular response to cytokine stimulusGO:00713451810.025
regulation of cell morphogenesis involved in differentiationGO:0010769830.025
maturation of ssu rrna from tricistronic rrna transcript ssu rrna 5 8s rrna lsu rrna GO:000046210.025
hindbrain developmentGO:003090230.024
regulation of cell cycleGO:00517263930.024
endocytosisGO:00068971590.024
positive regulation of hydrolase activityGO:00513453310.024
nuclear divisionGO:00002801280.024
positive regulation of protein modification by small protein conjugation or removalGO:1903322610.024
regulation of transferase activityGO:00513383550.024
organophosphate catabolic processGO:00464344300.024
purine nucleotide catabolic processGO:00061954050.023
stem cell developmentGO:0048864690.023
mitotic cell cycleGO:00002783260.023
coenzyme metabolic processGO:0006732650.023
cell cycle checkpointGO:00000751170.023
defense responseGO:00069523150.023
nuclear exportGO:0051168690.023
trna aminoacylationGO:0043039120.023
response to radiationGO:00093141510.023
cellular response to growth factor stimulusGO:00713631970.022
positive regulation of programmed cell deathGO:00430682490.022
regulation of intracellular transportGO:00323861950.022
positive regulation of nucleotide catabolic processGO:00308131850.022
regulation of pathway restricted smad protein phosphorylationGO:0060393340.022
regulation of protein ubiquitinationGO:0031396950.022
cellular protein complex assemblyGO:00436231880.022
positive regulation of cytokine productionGO:00018191670.022
macromolecular complex disassemblyGO:0032984600.022
regulation of cell cycle processGO:00105642660.021
embryo developmentGO:00097901230.021
Mouse Worm
cellular response to organonitrogen compoundGO:00714171240.021
positive regulation of cellular catabolic processGO:00313312840.021
lymphocyte activationGO:00466491330.021
anterior posterior axis specification embryoGO:000859520.021
reproductionGO:0000003630.021
Mouse Worm
nuclear transportGO:00511691790.021
response to nitrogen compoundGO:19016981840.021
alpha amino acid metabolic processGO:1901605720.021
maintenance of locationGO:00512351120.020
rna localizationGO:0006403410.020
regulation of anatomical structure morphogenesisGO:00226032860.020
negative regulation of cell cycle phase transitionGO:1901988890.019
cellular response to abiotic stimulusGO:00712141170.019
cytokine productionGO:00018162470.019
purine ribonucleotide catabolic processGO:00091544040.019
anatomical structure formation involved in morphogenesisGO:00486462840.019
ribosomal small subunit biogenesisGO:0042274130.019
proteasomal protein catabolic processGO:00104981760.018
regulation of apoptotic signaling pathwayGO:20012331750.018
negative regulation of phosphatase activityGO:0010923610.018
positive regulation of ras gtpase activityGO:00323201170.018
purine ribonucleoside monophosphate metabolic processGO:00091671860.018
leukocyte activationGO:00453211640.018
mrna processingGO:00063971330.018
rna transportGO:0050658390.018
blastoderm segmentationGO:000735020.018
cell morphogenesisGO:00009022960.018
guanosine containing compound metabolic processGO:19010682440.018
regulation of locomotionGO:00400123290.018
positive regulation of ligase activityGO:0051351190.018
response to oxygen containing compoundGO:19017003690.017
purine ribonucleoside monophosphate catabolic processGO:00091691580.017
positive regulation of purine nucleotide catabolic processGO:00331231850.017
cellular amine metabolic processGO:0044106410.017
vasculature developmentGO:00019441810.017
regulation of mrna metabolic processGO:1903311530.017
dna recombinationGO:0006310770.016
protein ubiquitinationGO:00165673140.016
regulation of protein bindingGO:0043393660.016
signal transduction by phosphorylationGO:00230142970.016
negative regulation of developmental processGO:00510932470.016
regulation of epithelial cell proliferationGO:00506781130.016
negative regulation of sequence specific dna binding transcription factor activityGO:0043433890.016
ras protein signal transductionGO:0007265730.016
regulation of defense responseGO:00313471540.016
nucleoside triphosphate metabolic processGO:00091414220.016
cell cell signalingGO:00072671550.016
nucleobase containing compound transportGO:0015931510.016
amine metabolic processGO:0009308440.016
response to woundingGO:00096111680.015
negative regulation of phosphorus metabolic processGO:00105632670.015
tripartite regional subdivisionGO:000735120.015
organelle assemblyGO:00709251760.015
dna damage response signal transduction by p53 class mediatorGO:0030330440.015
divalent inorganic cation homeostasisGO:00725071360.015
ossificationGO:00015031210.015
cellular protein catabolic processGO:00442572610.015
dorsal ventral pattern formationGO:0009953150.015
lipid localizationGO:00108761060.014
nucleoside monophosphate metabolic processGO:00091231910.014
signal transduction by p53 class mediatorGO:0072331720.014
posttranscriptional gene silencing by rnaGO:0035194250.014
motor neuron axon guidanceGO:000804520.014
positive regulation of immune system processGO:00026842830.014
regulation of small gtpase mediated signal transductionGO:00510561560.014
positive regulation of developmental processGO:00510943140.014
Worm
negative regulation of cell cycle processGO:00109481210.014
negative regulation of cell differentiationGO:00455961710.014
endomembrane system organizationGO:00102561960.014
apoptotic mitochondrial changesGO:0008637570.013
regulation of dephosphorylationGO:0035303960.013
spindle elongationGO:005123140.013
response to purine containing compoundGO:0014074400.013
organophosphate biosynthetic processGO:00904071630.013
actin filament based processGO:00300292240.013
regulation of protein serine threonine kinase activityGO:00719001790.013
establishment of organelle localizationGO:0051656590.013
mitotic cell cycle processGO:19030472860.013
dna replicationGO:00062601160.013
stress activated mapk cascadeGO:0051403930.013
positive regulation of cell deathGO:00109422630.013
gene silencingGO:0016458490.013
negative regulation of intracellular signal transductionGO:19025321830.013
cellular response to organic cyclic compoundGO:00714071270.013
single organism cellular localizationGO:19025803320.012
cell activationGO:00017752130.012
regulation of dna repairGO:0006282470.012
positive regulation of cell differentiationGO:00455972110.012
cell cycle phase transitionGO:00447701730.012
negative regulation of transferase activityGO:00513481240.012
positive regulation of protein catabolic processGO:0045732750.012
ribonucleotide catabolic processGO:00092614050.012
ubiquitin dependent protein catabolic processGO:00065112060.012
regulation of cell growthGO:00015581350.012
regulation of cytokine productionGO:00018172320.012
epithelial cell differentiationGO:00308551410.012
regulation of protein kinase activityGO:00458592890.012
regulation of protein catabolic processGO:00421761550.012
dephosphorylationGO:00163112090.012
regulation of immune responseGO:00507762010.012
maturation of 5 8s rrna from tricistronic rrna transcript ssu rrna 5 8s rrna lsu rrna GO:000046620.012
rhythmic behaviorGO:000762220.012
spermatid differentiationGO:004851540.012
chemotaxisGO:00069351570.012
cytokine mediated signaling pathwayGO:00192211090.012
regulation of cell morphogenesisGO:00226041530.011
negative regulation of transcription from rna polymerase ii promoterGO:00001222810.011
negative regulation of multicellular organismal processGO:00512413170.011
regulation of response to external stimulusGO:00321012220.011
cellular modified amino acid metabolic processGO:0006575640.011
positive regulation of transportGO:00510503360.011
cation transportGO:00068123310.011
cellular response to oxygen containing compoundGO:19017012760.011
regulation of gtpase activityGO:00430871800.011
purine nucleoside monophosphate metabolic processGO:00091261860.011
negative regulation of cellular component organizationGO:00511292350.011
cell growthGO:00160491600.011
positive regulation of cellular amino acid metabolic processGO:004576430.011
rna interferenceGO:001624640.011
atp catabolic processGO:00062001570.011
regulation of transmembrane receptor protein serine threonine kinase signaling pathwayGO:0090092900.011
single organism membrane organizationGO:00448022680.011
meiosis iGO:000712740.011
positive regulation of intracellular protein transportGO:0090316760.011
regulation of endodeoxyribonuclease activityGO:003207130.011
negative regulation of phosphate metabolic processGO:00459362670.010
regulation of proteolysis involved in cellular protein catabolic processGO:1903050910.010
protein maturationGO:00516042330.010
cell projection organizationGO:00300302520.010
pattern specification processGO:0007389430.010
positive regulation of purine nucleotide metabolic processGO:19005442270.010
dna catabolic processGO:0006308490.010
cellular response to nitrogen compoundGO:19016991440.010
regulation of phosphatase activityGO:0010921810.010
regulation of nuclear divisionGO:0051783650.010
negative regulation of cell motilityGO:20001461040.010
mitotic cell cycle checkpointGO:0007093680.010
nucleic acid phosphodiester bond hydrolysisGO:00903051020.010

EIF2S2 disease predictions

DiseaseDO term IDSizeProbabilityFunc Analog Org
neuropathyDOID:870520.040
neuromuscular diseaseDOID:440380.040
nervous system diseaseDOID:8634310.040
disease of metabolismDOID:00146672950.026
cancerDOID:1621670.019
disease of cellular proliferationDOID:145661740.019
organ system cancerDOID:00506861640.019
central nervous system diseaseDOID:3311860.014
inherited metabolic disorderDOID:6552420.014
musculoskeletal system diseaseDOID:172230.010