Homo sapiens

6 known processes

HPS1

Hermansky-Pudlak syndrome 1

(Aliases: HPS,MGC5277)

HPS1 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
cellular amine metabolic processGO:0044106410.069
post embryonic developmentGO:000979120.057
amine metabolic processGO:0009308440.053
cellular amino acid metabolic processGO:00065201160.052
vesicle mediated transportGO:00161923710.050
regulation of cellular amino acid metabolic processGO:000652160.049
cellular ketone metabolic processGO:0042180800.049
immune responseGO:00069553070.049
female gamete generationGO:000729220.045
small gtpase mediated signal transductionGO:0007264780.045
determination of adult lifespanGO:000834020.045
multicellular organismal agingGO:001025930.045
lipid metabolic processGO:00066293810.045
positive regulation of cellular amine metabolic processGO:003324070.044
regulation of cellular ketone metabolic processGO:0010565500.043
positive regulation of cellular amino acid metabolic processGO:004576430.042
transmembrane transportGO:00550853990.041
nucleotide catabolic processGO:00091664080.040
chemical homeostasisGO:00488783060.040
cellular lipid metabolic processGO:00442553030.038
regulation of cellular amine metabolic processGO:0033238110.038
regulation of cellular component biogenesisGO:00440872810.038
oogenesisGO:004847720.038
cation transportGO:00068123310.037
ras protein signal transductionGO:0007265730.035
cytoplasmic transportGO:00164823790.035
positive regulation of immune system processGO:00026842830.034
Mouse
cellular component morphogenesisGO:00329893140.033
nucleoside phosphate catabolic processGO:19012924120.032
purine nucleoside triphosphate metabolic processGO:00091444120.032
system processGO:00030083490.032
negative regulation of catalytic activityGO:00430863350.031
ion homeostasisGO:00508012300.031
segmentationGO:003528240.031
purine ribonucleotide catabolic processGO:00091544040.031
cellular homeostasisGO:00197251960.031
nucleoside triphosphate catabolic processGO:00091433940.030
purine ribonucleoside triphosphate metabolic processGO:00092054110.030
positive regulation of phosphorylationGO:00423273940.030
purine ribonucleoside metabolic processGO:00461284370.030
ribonucleoside catabolic processGO:00424544060.029
glycosyl compound catabolic processGO:19016584130.029
ribonucleoside triphosphate catabolic processGO:00092033910.029
ribonucleotide catabolic processGO:00092614050.029
purine nucleoside catabolic processGO:00061523980.029
ion transmembrane transportGO:00342203380.029
organophosphate catabolic processGO:00464344300.029
single organism membrane organizationGO:00448022680.028
response to abiotic stimulusGO:00096283360.028
regulation of locomotionGO:00400123290.028
defense responseGO:00069523150.028
response to oxygen containing compoundGO:19017003690.028
purine nucleotide catabolic processGO:00061954050.028
nervous system developmentGO:00073992930.027
regulation of cellular component movementGO:00512703340.027
cell morphogenesisGO:00009022960.027
positive regulation of transportGO:00510503360.027
cellular macromolecular complex assemblyGO:00346223240.027
negative regulation of protein metabolic processGO:00512483910.027
protein targetingGO:00066051870.027
biological adhesionGO:00226103310.027
purine containing compound catabolic processGO:00725234110.027
regulation of immune responseGO:00507762010.027
regulation of cell differentiationGO:00455953930.027
nucleoside triphosphate metabolic processGO:00091414220.027
locomotory behaviorGO:000762610.026
cation homeostasisGO:00550801890.026
cellular response to oxygen containing compoundGO:19017012760.026
intracellular protein transportGO:00068862700.026
purine ribonucleoside catabolic processGO:00461303980.026
regulation of cell cycleGO:00517263930.026
secretion by cellGO:00329402260.025
Mouse
memoryGO:000761330.025
positive regulation of cellular component organizationGO:00511303760.025
purine ribonucleoside triphosphate catabolic processGO:00092073910.025
negative regulation of apoptotic processGO:00430663160.025
response to cytokineGO:00340972320.025
positive regulation of nucleotide metabolic processGO:00459812300.025
positive regulation of catabolic processGO:00098963100.025
ribonucleoside triphosphate metabolic processGO:00091994120.024
oxidation reduction processGO:00551143960.024
purine nucleoside triphosphate catabolic processGO:00091463920.024
regulation of kinase activityGO:00435493140.024
response to external biotic stimulusGO:00432072610.024
dephosphorylationGO:00163112090.024
regulation of anatomical structure morphogenesisGO:00226032860.024
actin filament based processGO:00300292240.024
cell adhesionGO:00071553250.024
cytokine productionGO:00018162470.024
lipid biosynthetic processGO:00086101770.024
negative regulation of cellular component organizationGO:00511292350.024
positive regulation of hydrolase activityGO:00513453310.024
regulation of purine nucleotide metabolic processGO:19005422640.023
regulation of protein localizationGO:00328802960.023
metal ion transportGO:00300012720.023
single organism cellular localizationGO:19025803320.023
negative regulation of cellular protein metabolic processGO:00322693530.023
negative regulation of programmed cell deathGO:00430693210.023
positive regulation of cellular catabolic processGO:00313312840.023
negative regulation of phosphorus metabolic processGO:00105632670.022
cellular cation homeostasisGO:00300031630.022
negative regulation of phosphate metabolic processGO:00459362670.022
posttranscriptional regulation of gene expressionGO:00106082130.022
cellular macromolecule catabolic processGO:00442653800.022
nucleoside catabolic processGO:00091644080.022
response to other organismGO:00517072610.022
regenerationGO:003109940.022
regulation of protein kinase activityGO:00458592890.022
regulation of cell motilityGO:20001452990.022
oocyte differentiationGO:000999420.022
protein catabolic processGO:00301633250.022
anion transportGO:00068201610.022
regulation of response to external stimulusGO:00321012220.022
epithelium developmentGO:00604292270.022
Mouse
positive regulation of immune responseGO:00507781590.021
carbohydrate metabolic processGO:00059752070.021
blastoderm segmentationGO:000735020.021
mitotic cell cycleGO:00002783260.021
regulation of proteolysisGO:00301622930.021
cell activationGO:00017752130.021
Mouse
regulation of nucleotide metabolic processGO:00061402690.021
membrane organizationGO:00610242920.021
neuromuscular junction developmentGO:000752830.021
protein maturationGO:00516042330.021
response to biotic stimulusGO:00096072760.021
negative regulation of cell deathGO:00605483450.021
regulation of transferase activityGO:00513383550.021
hematopoietic or lymphoid organ developmentGO:00485341860.021
organophosphate biosynthetic processGO:00904071630.021
cell projection organizationGO:00300302520.020
cellular response to dna damage stimulusGO:00069743790.020
gtp metabolic processGO:00460392390.020
cellular chemical homeostasisGO:00550821800.020
innate immune responseGO:00450871780.020
regulation of secretionGO:00510461940.020
cellular ion homeostasisGO:00068731680.020
regulation of cytokine productionGO:00018172320.020
protein localization to organelleGO:00333652800.020
inorganic cation transmembrane transportGO:00986621940.020
vacuole organizationGO:0007033440.020
regulation of cellular response to stressGO:00801352440.020
gtp catabolic processGO:00061842370.020
immune system developmentGO:00025201950.020
endomembrane system organizationGO:00102561960.020
protein processingGO:00164852260.020
positive regulation of protein phosphorylationGO:00019343130.019
anterior posterior axis specificationGO:000994820.019
regulation of ras protein signal transductionGO:00465781550.019
rho protein signal transductionGO:0007266260.019
regulation of small gtpase mediated signal transductionGO:00510561560.019
cation transmembrane transportGO:00986552380.019
positive regulation of purine nucleotide metabolic processGO:19005442270.019
small molecule biosynthetic processGO:00442831570.019
regulation of cell cycle processGO:00105642660.019
microtubule based processGO:00070172100.018
negative regulation of cellular amine metabolic processGO:003323930.018
single organism carbohydrate metabolic processGO:00447231930.018
regulation of secretion by cellGO:19035301770.018
positive regulation of cell deathGO:00109422630.018
guanosine containing compound catabolic processGO:19010692390.018
endosomal transportGO:00161971290.018
positive regulation of cell proliferationGO:00082843010.018
regulation of establishment of protein localizationGO:00702012420.018
oocyte developmentGO:004859910.018
regulation of protein transportGO:00512232130.018
positive regulation of kinase activityGO:00336742040.018
regulation of purine nucleotide catabolic processGO:00331212050.018
positive regulation of developmental processGO:00510943140.018
cellular response to endogenous stimulusGO:00714953360.018
response to organonitrogen compoundGO:00102431560.018
positive regulation of organelle organizationGO:00106381950.018
mitotic cell cycle processGO:19030472860.018
cellular protein complex assemblyGO:00436231880.018
cellular response to cytokine stimulusGO:00713451810.018
carbohydrate derivative biosynthetic processGO:19011372070.018
anatomical structure formation involved in morphogenesisGO:00486462840.018
regulation of cytoskeleton organizationGO:00514931770.017
response to radiationGO:00093141510.017
regulation of ion transportGO:00432691890.017
regulation of cell migrationGO:00303342890.017
regulation of nucleotide catabolic processGO:00308112050.017
negative regulation of multicellular organismal processGO:00512413170.017
response to nitrogen compoundGO:19016981840.017
spermatid differentiationGO:004851540.017
adult locomotory behaviorGO:000834410.017
apoptotic signaling pathwayGO:00971902680.017
nitrogen compound transportGO:00717051910.017
secretionGO:00469032540.017
Mouse
organonitrogen compound biosynthetic processGO:19015662000.017
regulation of sequence specific dna binding transcription factor activityGO:00510902110.016
guanosine containing compound metabolic processGO:19010682440.016
positive regulation of transferase activityGO:00513472270.016
hemopoiesisGO:00300971800.016
metal ion homeostasisGO:00550651690.016
regulation of gtpase activityGO:00430871800.016
glycoprotein metabolic processGO:00091001100.016
positive regulation of apoptotic processGO:00430652460.016
protein modification by small protein conjugationGO:00324463420.016
organelle assemblyGO:00709251760.016
regulation of mapk cascadeGO:00434082620.016
cellular protein catabolic processGO:00442572610.016
regulation of synaptic plasticityGO:004816730.016
positive regulation of cellular component movementGO:00512721810.016
negative regulation of intracellular signal transductionGO:19025321830.016
negative regulation of cellular amino acid metabolic processGO:004576320.016
enzyme linked receptor protein signaling pathwayGO:00071673030.016
maintenance of locationGO:00512351120.016
regulation of leukocyte activationGO:00026941150.016
Mouse
actin cytoskeleton organizationGO:00300362070.016
positive regulation of protein kinase activityGO:00458601900.016
negative regulation of protein modification processGO:00314002000.016
response to bacteriumGO:00096171440.016
purine ribonucleoside monophosphate metabolic processGO:00091671860.015
positive regulation of locomotionGO:00400171860.015
growthGO:00400072020.015
regulation of cell activationGO:00508651250.015
Mouse
positive regulation of cell migrationGO:00303351720.015
negative regulation of hydrolase activityGO:00513461820.015
neurological system processGO:00508771630.015
negative regulation of immune system processGO:00026831360.015
regulation of intracellular transportGO:00323861950.015
positive regulation of programmed cell deathGO:00430682490.015
cell developmentGO:00484683280.015
regulation of protein complex assemblyGO:00432541470.015
proteolysis involved in cellular protein catabolic processGO:00516032440.015
monocarboxylic acid metabolic processGO:00327871850.015
regulation of nucleoside metabolic processGO:00091182090.015
negative regulation of phosphorylationGO:00423261740.015
protein ubiquitinationGO:00165673140.015
proteasomal protein catabolic processGO:00104981760.015
sulfur compound metabolic processGO:00067901010.015
regulation of protein catabolic processGO:00421761550.015
reactive nitrogen species metabolic processGO:200105730.015
cell cycle phase transitionGO:00447701730.015
inorganic ion transmembrane transportGO:00986602310.015
leukocyte activationGO:00453211640.015
Mouse
tripartite regional subdivisionGO:000735120.015
divalent inorganic cation transportGO:00725111580.015
spermatid developmentGO:000728640.015
regulation of lymphocyte activationGO:00512491030.015
Mouse
organic acid biosynthetic processGO:0016053970.015
divalent metal ion transportGO:00708381520.014
response to organic cyclic compoundGO:00140702040.014
cellular metal ion homeostasisGO:00068751460.014
plasma membrane organizationGO:00070091150.014
negative regulation of transcription from rna polymerase ii promoterGO:00001222810.014
protein oligomerizationGO:00512591730.014
phospholipid metabolic processGO:0006644990.014
morphogenesis of embryonic epitheliumGO:001633140.014
reactive oxygen species metabolic processGO:0072593750.014
immune effector processGO:00022521590.014
anterior posterior axis specification embryoGO:000859520.014
endocytosisGO:00068971590.014
negative regulation of cell cycleGO:00457861930.014
regulation of protein maturationGO:19033171500.014
histone modificationGO:00165702510.014
t cell activationGO:0042110990.014
negative regulation of cell proliferationGO:00082852280.014
signal transduction by phosphorylationGO:00230142970.014
covalent chromatin modificationGO:00165692540.014
symbiosis encompassing mutualism through parasitismGO:00444031560.014
positive regulation of nucleoside metabolic processGO:00459791860.014
interspecies interaction between organismsGO:00444191560.014
glycerolipid metabolic processGO:00464861070.014
peptidyl tyrosine phosphorylationGO:00181081700.014
modification dependent macromolecule catabolic processGO:00436322120.014
regulation of growthGO:00400081650.014
chromatin modificationGO:00165682980.014
hindbrain developmentGO:003090230.013
regulation of mitotic cell cycleGO:00073461890.013
protein localization to membraneGO:00726571600.013
compound eye developmentGO:004874910.013
negative regulation of developmental processGO:00510932470.013
reactive oxygen species biosynthetic processGO:190340940.013
carboxylic acid biosynthetic processGO:0046394970.013
regulation of protein stabilityGO:0031647870.013
ubiquitin dependent protein catabolic processGO:00065112060.013
ribonucleoside monophosphate metabolic processGO:00091611870.013
lymphocyte activationGO:00466491330.013
Mouse
regulation of cell adhesionGO:00301551660.013
response to lipidGO:00339932060.013
microtubule cytoskeleton organizationGO:00002261760.013
cellular response to abiotic stimulusGO:00712141170.013
purine nucleoside monophosphate metabolic processGO:00091261860.013
regulation of multi organism processGO:00439001570.013
sequestering of metal ionGO:0051238240.013
epithelial cell differentiationGO:00308551410.013
Mouse
regulation of cell morphogenesisGO:00226041530.013
chromatin organizationGO:00063253510.013
lytic vacuole organizationGO:0080171240.013
nucleoside monophosphate metabolic processGO:00091231910.013
response to hormoneGO:00097251750.013
regulation of gtp catabolic processGO:00331241800.013
rhythmic behaviorGO:000762220.013
regulation of i kappab kinase nf kappab signalingGO:00431221620.013
organic anion transportGO:00157111030.013
circadian behaviorGO:004851220.013
divalent inorganic cation homeostasisGO:00725071360.013
modification dependent protein catabolic processGO:00199412090.013
cell growthGO:00160491600.013
proteasome mediated ubiquitin dependent protein catabolic processGO:00431611560.013
response to fungusGO:000962040.013
positive regulation of cell differentiationGO:00455972110.013
negative regulation of protein phosphorylationGO:00019331400.013
regulation of meiotic cell cycleGO:005144540.013
associative learningGO:000830610.013
mapk cascadeGO:00001652880.013
long term memoryGO:000761620.013
regulation of protein serine threonine kinase activityGO:00719001790.013
positive regulation of purine nucleotide catabolic processGO:00331231850.012
syncytium formation by plasma membrane fusionGO:000076820.012
metencephalon developmentGO:002203720.012
cellular divalent inorganic cation homeostasisGO:00725031280.012
protein stabilizationGO:0050821640.012
multi organism cellular processGO:00447641560.012
ribose phosphate biosynthetic processGO:0046390820.012
cell substrate adhesionGO:00315891320.012
protein acylationGO:00435431380.012
negative regulation of organelle organizationGO:00106391260.012
atp metabolic processGO:00460341760.012
morphogenesis of a polarized epitheliumGO:000173830.012
activation of immune responseGO:00022531140.012
cellular response to organonitrogen compoundGO:00714171240.012
negative regulation of transportGO:00510511760.012
embryonic epithelial tube formationGO:000183840.012
positive regulation of gtp catabolic processGO:00331261660.012
regulation of ras gtpase activityGO:00323181280.012
positive regulation of nucleotide catabolic processGO:00308131850.012
negative regulation of proteolysisGO:00458611320.012
myeloid cell differentiationGO:00300991170.012
negative regulation of protein processingGO:00109551420.012
cell divisionGO:00513011680.012
regulation of dephosphorylationGO:0035303960.012
peptidyl tyrosine modificationGO:00182121700.012
organelle fissionGO:00482851490.012
motor neuron axon guidanceGO:000804520.012
positive regulation of cytokine productionGO:00018191670.012
positive regulation of cellular component biogenesisGO:00440891580.012
cellular response to nitrogen compoundGO:19016991440.012
cell type specific apoptotic processGO:00972851250.012
blood circulationGO:00080151130.012
regulation of neural precursor cell proliferationGO:200017740.012
positive regulation of proteolysisGO:00458621420.012
photoreceptor cell differentiationGO:004653020.012
neurogenesisGO:00220081690.012
mitotic cell cycle phase transitionGO:00447721620.012
detection of stimulusGO:0051606850.012
regulation of actin filament based processGO:00329701410.012
positive regulation of gtpase activityGO:00435471660.012
regulation of vesicle mediated transportGO:00606271300.012
calcium ion transportGO:00068161470.011
behaviorGO:00076101120.011
wnt signaling pathwayGO:00160551560.011
positive regulation of secretionGO:00510471160.011
protein localization to nucleusGO:00345041360.011
nucleocytoplasmic transportGO:00069131760.011
regulation of phosphatase activityGO:0010921810.011
regulation of reactive oxygen species biosynthetic processGO:190342630.011
regulation of protein processingGO:00706131500.011
cell morphogenesis involved in differentiationGO:00009041440.011
negative regulation of transferase activityGO:00513481240.011
positive regulation of cell motilityGO:20001471770.011
lysosome organizationGO:0007040240.011
nuclear transportGO:00511691790.011
regulation of endopeptidase activityGO:00525481700.011
organ formationGO:004864530.011
positive regulation of protein transportGO:00512221350.011
regulation of immune effector processGO:0002697910.011
purine ribonucleoside monophosphate catabolic processGO:00091691580.011
actin filament organizationGO:00070151280.011
sequestering of calcium ionGO:0051208170.011
nucleotide biosynthetic processGO:00091651090.011
regulation of cell cycle phase transitionGO:19019871260.011
cell fate determinationGO:000170930.011
positive regulation of mapk cascadeGO:00434101900.011
defense response to other organismGO:00985421290.011
cell projection morphogenesisGO:00488581290.011
atp catabolic processGO:00062001570.011
positive regulation of synaptic transmissionGO:005080640.011
ameboidal type cell migrationGO:00016671350.011
regulation of metal ion transportGO:00109591200.011
immune response regulating signaling pathwayGO:0002764970.011
viral processGO:00160321460.011
protein autophosphorylationGO:00467771230.011
alcohol metabolic processGO:00060661140.011
mitochondrion organizationGO:00070051560.011
peripheral nervous system developmentGO:000742220.011
mitotic nuclear divisionGO:00070671190.011
fatty acid metabolic processGO:00066311150.011
blood vessel developmentGO:00015681720.011
negative regulation of protein maturationGO:19033181420.011
central nervous system developmentGO:00074171230.011
inner ear morphogenesisGO:004247240.011
circulatory system developmentGO:00723592620.011
regulation of reactive oxygen species metabolic processGO:2000377410.011
cerebellum developmentGO:002154920.011
cellular calcium ion homeostasisGO:00068741170.011
monovalent inorganic cation transportGO:00156721280.011
organ morphogenesisGO:00098871470.011
muscle contractionGO:0006936730.010
lipid transportGO:0006869900.010
establishment of protein localization to organelleGO:00725941720.010
regulation of cytoplasmic transportGO:19036491490.010
phototransductionGO:000760230.010
regulation of cell growthGO:00015581350.010
dna repairGO:00062811980.010
limbic system developmentGO:002176130.010
response to inorganic substanceGO:00100351270.010
glycoprotein biosynthetic processGO:0009101910.010
receptor metabolic processGO:0043112810.010
establishment of protein localization to membraneGO:00901501210.010
protein secretionGO:0009306980.010
Mouse
immune response activating signal transductionGO:0002757900.010
rna processingGO:00063962550.010
cell projection assemblyGO:00300311260.010
regulation of peptidase activityGO:00525471800.010
glycerophospholipid metabolic processGO:0006650840.010
cell part morphogenesisGO:00329901370.010
response to woundingGO:00096111680.010
Mouse
regulation of defense responseGO:00313471540.010
cellular response to organic cyclic compoundGO:00714071270.010
negative regulation of catabolic processGO:00098951040.010
monocarboxylic acid biosynthetic processGO:0072330670.010
meiotic chromosome segregationGO:004513240.010
peptidyl serine phosphorylationGO:00181051010.010
positive regulation of protein serine threonine kinase activityGO:00719021190.010
salivary gland morphogenesisGO:000743540.010

HPS1 disease predictions

DiseaseDO term IDSizeProbabilityFunc Analog Org
inherited metabolic disorderDOID:6552420.069
disease of metabolismDOID:00146672950.069
musculoskeletal system diseaseDOID:172230.033
connective tissue diseaseDOID:651090.029
sensory system diseaseDOID:00501552030.021
nervous system diseaseDOID:8634310.021
central nervous system diseaseDOID:3311860.020
bone diseaseDOID:0080001880.020
cancerDOID:1621670.017
disease of cellular proliferationDOID:145661740.017
organ system cancerDOID:00506861640.017
lysosomal storage diseaseDOID:3211470.017
immune system diseaseDOID:29141550.016
eye diseaseDOID:56141490.014
eye and adnexa diseaseDOID:14921500.014
retinal diseaseDOID:56791180.013
muscle tissue diseaseDOID:661130.013
muscular diseaseDOID:00800001140.013
neurodegenerative diseaseDOID:12891020.012
myopathyDOID:4231040.011