Homo sapiens

0 known processes

PI4KA

phosphatidylinositol 4-kinase, catalytic, alpha

(Aliases: PIK4CA,PI4K-ALPHA,pi4K230,FLJ16556)

PI4KA biological process predictions


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Biological processGO term IDProcess sizeProbabilityFunc Analog Org
ribonucleotide catabolic processGO:00092614050.084
nucleoside phosphate catabolic processGO:19012924120.077
ribonucleoside triphosphate metabolic processGO:00091994120.074
ras protein signal transductionGO:0007265730.070
purine ribonucleoside metabolic processGO:00461284370.069
nucleoside catabolic processGO:00091644080.069
post embryonic developmentGO:000979120.065
purine nucleoside triphosphate metabolic processGO:00091444120.061
purine ribonucleoside catabolic processGO:00461303980.060
small gtpase mediated signal transductionGO:0007264780.059
nucleotide catabolic processGO:00091664080.059
actin filament based processGO:00300292240.058
lipid metabolic processGO:00066293810.058
glycosyl compound catabolic processGO:19016584130.055
endomembrane system organizationGO:00102561960.054
ribonucleoside catabolic processGO:00424544060.053
purine ribonucleoside triphosphate metabolic processGO:00092054110.051
vesicle mediated transportGO:00161923710.050
guanosine containing compound metabolic processGO:19010682440.050
purine nucleoside triphosphate catabolic processGO:00091463920.049
organophosphate catabolic processGO:00464344300.044
purine ribonucleotide catabolic processGO:00091544040.044
cellular macromolecular complex assemblyGO:00346223240.042
ribonucleoside triphosphate catabolic processGO:00092033910.042
positive regulation of nucleotide metabolic processGO:00459812300.041
purine containing compound catabolic processGO:00725234110.041
cellular amino acid metabolic processGO:00065201160.041
nucleoside triphosphate catabolic processGO:00091433940.041
cellular ketone metabolic processGO:0042180800.040
nucleoside triphosphate metabolic processGO:00091414220.040
purine nucleotide catabolic processGO:00061954050.039
regulation of gtp catabolic processGO:00331241800.038
negative regulation of cellular protein metabolic processGO:00322693530.038
regulation of nucleoside metabolic processGO:00091182090.038
cellular amine metabolic processGO:0044106410.037
purine nucleoside catabolic processGO:00061523980.037
positive regulation of hydrolase activityGO:00513453310.037
oogenesisGO:004847720.037
regulation of cellular amine metabolic processGO:0033238110.036
regulation of ras gtpase activityGO:00323181280.036
positive regulation of purine nucleotide metabolic processGO:19005442270.036
regulation of cellular amino acid metabolic processGO:000652160.036
gtp catabolic processGO:00061842370.035
purine ribonucleoside triphosphate catabolic processGO:00092073910.035
gtp metabolic processGO:00460392390.035
amine metabolic processGO:0009308440.035
regulation of purine nucleotide metabolic processGO:19005422640.034
positive regulation of catabolic processGO:00098963100.034
positive regulation of nucleotide catabolic processGO:00308131850.033
single organism carbohydrate metabolic processGO:00447231930.032
female gamete generationGO:000729220.032
determination of adult lifespanGO:000834020.032
regulation of nucleotide metabolic processGO:00061402690.032
single organism cellular localizationGO:19025803320.032
guanosine containing compound catabolic processGO:19010692390.031
positive regulation of cellular catabolic processGO:00313312840.031
transmembrane transportGO:00550853990.031
glycerophospholipid metabolic processGO:0006650840.031
rho protein signal transductionGO:0007266260.031
regulation of cellular ketone metabolic processGO:0010565500.030
cellular lipid metabolic processGO:00442553030.030
positive regulation of ras gtpase activityGO:00323201170.030
regulation of nucleotide catabolic processGO:00308112050.029
memoryGO:000761330.029
cytoplasmic transportGO:00164823790.029
mitotic cell cycle processGO:19030472860.029
positive regulation of purine nucleotide catabolic processGO:00331231850.028
positive regulation of nucleoside metabolic processGO:00459791860.028
nervous system developmentGO:00073992930.028
negative regulation of protein metabolic processGO:00512483910.028
positive regulation of gtpase activityGO:00435471660.027
embryonic epithelial tube formationGO:000183840.027
membrane organizationGO:00610242920.027
regulation of protein serine threonine kinase activityGO:00719001790.027
nitrogen compound transportGO:00717051910.027
regulation of purine nucleotide catabolic processGO:00331212050.026
multicellular organismal agingGO:001025930.026
response to abiotic stimulusGO:00096283360.026
system processGO:00030083490.025
negative regulation of programmed cell deathGO:00430693210.025
organic hydroxy compound metabolic processGO:19016151470.025
cellular component morphogenesisGO:00329893140.025
regulation of protein localizationGO:00328802960.025
chromatin organizationGO:00063253510.024
regulation of cell motilityGO:20001452990.024
carbohydrate metabolic processGO:00059752070.024
neural tube formationGO:000184130.024
regulation of gtpase activityGO:00430871800.024
morphogenesis of embryonic epitheliumGO:001633140.024
positive regulation of cellular component organizationGO:00511303760.024
maintenance of locationGO:00512351120.024
negative regulation of catalytic activityGO:00430863350.023
protein localization to organelleGO:00333652800.023
lipid biosynthetic processGO:00086101770.023
single organism membrane organizationGO:00448022680.023
mitotic cell cycleGO:00002783260.023
primary neural tube formationGO:001402030.022
positive regulation of transportGO:00510503360.022
negative regulation of cellular amino acid metabolic processGO:004576320.022
small molecule biosynthetic processGO:00442831570.022
oocyte differentiationGO:000999420.022
signal transduction by phosphorylationGO:00230142970.022
neuromuscular junction developmentGO:000752830.022
segmentationGO:003528240.022
rab protein signal transductionGO:003248240.022
locomotory behaviorGO:000762610.021
positive regulation of cellular amino acid metabolic processGO:004576430.021
defense responseGO:00069523150.021
regulation of rab gtpase activityGO:0032313390.021
regulation of establishment of protein localizationGO:00702012420.021
oocyte developmentGO:004859910.021
inorganic ion transmembrane transportGO:00986602310.021
regenerationGO:003109940.020
cell morphogenesisGO:00009022960.020
mapk cascadeGO:00001652880.020
regulation of cellular component movementGO:00512703340.020
posttranscriptional regulation of gene expressionGO:00106082130.020
catecholamine secretionGO:005043210.020
intracellular protein transportGO:00068862700.020
organonitrogen compound biosynthetic processGO:19015662000.020
secretionGO:00469032540.020
associative learningGO:000830610.020
organelle assemblyGO:00709251760.019
hindbrain developmentGO:003090230.019
actin filament organizationGO:00070151280.019
lipid modificationGO:0030258840.019
cell projection organizationGO:00300302520.019
regulation of transferase activityGO:00513383550.019
inorganic cation transmembrane transportGO:00986621940.019
regulation of ras protein signal transductionGO:00465781550.019
cation transmembrane transportGO:00986552380.019
regulation of anatomical structure morphogenesisGO:00226032860.018
inner ear morphogenesisGO:004247240.018
positive regulation of phosphorylationGO:00423273940.018
protein modification by small protein conjugationGO:00324463420.018
blastoderm segmentationGO:000735020.018
axon regenerationGO:003110310.018
atp metabolic processGO:00460341760.018
positive regulation of gtp catabolic processGO:00331261660.018
regulation of protein kinase activityGO:00458592890.018
regulation of cell cycleGO:00517263930.018
protein catabolic processGO:00301633250.018
dephosphorylationGO:00163112090.018
negative regulation of apoptotic processGO:00430663160.017
negative regulation of cellular amine metabolic processGO:003323930.017
actin filament based movementGO:0030048170.017
carbohydrate derivative biosynthetic processGO:19011372070.017
internal peptidyl lysine acetylationGO:0018393970.017
ribonucleoside monophosphate metabolic processGO:00091611870.017
peptidyl lysine acetylationGO:00183941010.017
protein maturationGO:00516042330.017
apoptotic signaling pathwayGO:00971902680.017
ribonucleoprotein complex assemblyGO:0022618780.017
cellular response to dna damage stimulusGO:00069743790.016
regulation of synaptic plasticityGO:004816730.016
negative regulation of phosphorus metabolic processGO:00105632670.016
glycerolipid metabolic processGO:00464861070.016
negative regulation of hydrolase activityGO:00513461820.016
long term memoryGO:000761620.016
endosomal transportGO:00161971290.016
axis elongationGO:000340140.016
regulation of proteolysisGO:00301622930.016
purine nucleoside monophosphate metabolic processGO:00091261860.016
cellular macromolecule catabolic processGO:00442653800.016
regulation of secretionGO:00510461940.016
negative regulation of transcription from rna polymerase ii promoterGO:00001222810.016
regulation of rab protein signal transductionGO:0032483390.016
purine ribonucleoside monophosphate metabolic processGO:00091671860.016
regulation of protein transportGO:00512232130.016
endocytosisGO:00068971590.016
ion transmembrane transportGO:00342203380.016
response to oxygen containing compoundGO:19017003690.016
actin cytoskeleton organizationGO:00300362070.016
nucleoside monophosphate metabolic processGO:00091231910.016
microtubule based processGO:00070172100.016
negative regulation of cellular component movementGO:00512711060.016
regulation of cell cycle processGO:00105642660.016
atp catabolic processGO:00062001570.016
neuron differentiationGO:00301821380.016
negative regulation of cell proliferationGO:00082852280.016
regulation of kinase activityGO:00435493140.016
non canonical wnt signaling pathway via mapk cascadeGO:003803040.016
cellular protein complex assemblyGO:00436231880.015
negative regulation of multicellular organismal processGO:00512413170.015
covalent chromatin modificationGO:00165692540.015
visual behaviorGO:000763220.015
response to fungusGO:000962040.015
cellular protein catabolic processGO:00442572610.015
cation transportGO:00068123310.015
cell adhesionGO:00071553250.015
secretion by cellGO:00329402260.015
modification dependent macromolecule catabolic processGO:00436322120.015
organ morphogenesisGO:00098871470.015
negative regulation of intracellular signal transductionGO:19025321830.015
negative regulation of cellular component organizationGO:00511292350.015
positive regulation of synaptic transmissionGO:005080640.015
anatomical structure formation involved in morphogenesisGO:00486462840.015
neurological system processGO:00508771630.015
anterior posterior axis specificationGO:000994820.015
regulation of mapk cascadeGO:00434082620.015
rna processingGO:00063962550.015
cellular response to endogenous stimulusGO:00714953360.015
salivary gland morphogenesisGO:000743540.015
tube closureGO:006060630.014
regulation of vesicle mediated transportGO:00606271300.014
visual learningGO:000854210.014
regulation of protein stabilityGO:0031647870.014
peripheral nervous system developmentGO:000742220.014
negative regulation of phosphate metabolic processGO:00459362670.014
regulation of small gtpase mediated signal transductionGO:00510561560.014
actin mediated cell contractionGO:0070252120.014
negative regulation of developmental processGO:00510932470.014
sensory perception of painGO:001923340.014
innate immune responseGO:00450871780.014
metal ion transportGO:00300012720.014
methylationGO:00322591060.014
regulation of growthGO:00400081650.014
positive regulation of transferase activityGO:00513472270.014
spermatid differentiationGO:004851540.014
wnt signaling pathwayGO:00160551560.014
cell projection assemblyGO:00300311260.014
establishment of protein localization to membraneGO:00901501210.014
cardiovascular system developmentGO:00723582620.014
positive regulation of cell proliferationGO:00082843010.014
growthGO:00400072020.014
protein acylationGO:00435431380.014
monovalent inorganic cation transportGO:00156721280.014
negative regulation of protein modification processGO:00314002000.014
biological adhesionGO:00226103310.013
response to growth factorGO:00708482050.013
proteolysis involved in cellular protein catabolic processGO:00516032440.013
mrna metabolic processGO:00160711750.013
positive regulation of cellular amine metabolic processGO:003324070.013
histone modificationGO:00165702510.013
spermatid developmentGO:000728640.013
central nervous system developmentGO:00074171230.013
morphogenesis of a polarized epitheliumGO:000173830.013
neuroblast proliferationGO:000740540.013
regulation of cellular response to stressGO:00801352440.013
adult locomotory behaviorGO:000834410.013
ion homeostasisGO:00508012300.013
negative regulation of transportGO:00510511760.013
organic acid biosynthetic processGO:0016053970.013
neural tube closureGO:000184330.013
microtubule cytoskeleton organizationGO:00002261760.013
response to other organismGO:00517072610.013
regulation of secretion by cellGO:19035301770.013
positive regulation of protein phosphorylationGO:00019343130.013
alcohol metabolic processGO:00060661140.013
cell part morphogenesisGO:00329901370.013
regulation of protein processingGO:00706131500.013
protein localization to membraneGO:00726571600.013
protein secretionGO:0009306980.013
somitogenesisGO:000175620.013
rhythmic behaviorGO:000762220.013
positive regulation of immune system processGO:00026842830.013
defense response to fungusGO:005083240.013
protein processingGO:00164852260.013
mitochondrion organizationGO:00070051560.013
regulation of cellular component biogenesisGO:00440872810.013
nerve developmentGO:002167540.013
neurogenesisGO:00220081690.012
response to axon injuryGO:004867810.012
metencephalon developmentGO:002203720.012
rna splicingGO:00083801310.012
anion transportGO:00068201610.012
ribonucleoprotein complex subunit organizationGO:0071826810.012
response to decreased oxygen levelsGO:0036293960.012
organophosphate biosynthetic processGO:00904071630.012
regulation of actin filament based processGO:00329701410.012
cation homeostasisGO:00550801890.012
matingGO:000761810.012
plasma membrane organizationGO:00070091150.012
cell projection morphogenesisGO:00488581290.012
cilium morphogenesisGO:0060271750.012
positive regulation of rab gtpase activityGO:0032851390.012
generation of neuronsGO:00486991520.012
protein acetylationGO:00064731160.012
tripartite regional subdivisionGO:000735120.012
neurotransmitter secretionGO:000726940.012
startle responseGO:000196430.012
protein targetingGO:00066051870.012
regulation of neural precursor cell proliferationGO:200017740.012
regulation of reactive oxygen species biosynthetic processGO:190342630.012
chemical homeostasisGO:00488783060.012
compound eye developmentGO:004874910.012
neuron projection developmentGO:00311751060.012
histone acetylationGO:0016573930.012
positive regulation of programmed cell deathGO:00430682490.012
phospholipid metabolic processGO:0006644990.012
establishment of planar polarityGO:000173630.012
cerebellum developmentGO:002154920.012
response to external biotic stimulusGO:00432072610.012
response to oxygen levelsGO:00704821000.012
negative regulation of cell cycleGO:00457861930.012
negative regulation of cell deathGO:00605483450.011
monocarboxylic acid metabolic processGO:00327871850.011
cell divisionGO:00513011680.011
circadian behaviorGO:004851220.011
positive regulation of cellular component biogenesisGO:00440891580.011
mitotic nuclear divisionGO:00070671190.011
positive regulation of protein transportGO:00512221350.011
carboxylic acid biosynthetic processGO:0046394970.011
regulation of immune responseGO:00507762010.011
negative regulation of organelle organizationGO:00106391260.011
regulation of multi organism processGO:00439001570.011
reactive nitrogen species metabolic processGO:200105730.011
cell growthGO:00160491600.011
response to biotic stimulusGO:00096072760.011
anterior posterior axis specification embryoGO:000859520.011
immune responseGO:00069553070.011
reproductive processGO:00224141060.011
head developmentGO:00603221080.011
establishment of tissue polarityGO:000716430.011
ribonucleoside monophosphate catabolic processGO:00091581580.011
purine ribonucleoside monophosphate catabolic processGO:00091691580.011
immune system developmentGO:00025201950.011
positive regulation of secretion by cellGO:19035321080.011
regulation of protein maturationGO:19033171500.011
positive regulation of secretionGO:00510471160.011
reactive oxygen species biosynthetic processGO:190340940.011
chromatin assembly or disassemblyGO:0006333780.011
chemotaxisGO:00069351570.011
protein dna complex subunit organizationGO:0071824800.011
photoreceptor cell differentiationGO:004653020.011
regulation of endopeptidase activityGO:00525481700.011
reactive oxygen species metabolic processGO:0072593750.011
hippocampus developmentGO:002176610.011
cell cycle phase transitionGO:00447701730.011
epithelium developmentGO:00604292270.011
regulation of dna metabolic processGO:00510521530.011
regulation of intracellular transportGO:00323861950.011
convergent extensionGO:006002610.011
hair cell differentiationGO:003531520.011
positive regulation of mapk cascadeGO:00434101900.011
regulation of protein catabolic processGO:00421761550.011
cardiac muscle cell contractionGO:008600340.011
embryo developmentGO:00097901230.011
protein stabilizationGO:0050821640.010
chromatin modificationGO:00165682980.010
regulation of cytoskeleton organizationGO:00514931770.010
dna repairGO:00062811980.010
organ formationGO:004864530.010
positive regulation of protein kinase activityGO:00458601900.010
negative regulation of locomotionGO:00400131180.010
positive regulation of developmental processGO:00510943140.010
epithelial cell differentiationGO:00308551410.010
regulation of dephosphorylationGO:0035303960.010
regulation of cell cycle phase transitionGO:19019871260.010
regulation of cytokine productionGO:00018172320.010
release of cytoplasmic sequestered nf kappabGO:000858840.010
negative regulation of cell migrationGO:00303361020.010
cell fate determinationGO:000170930.010
negative regulation of phosphorylationGO:00423261740.010
peptidyl lysine modificationGO:00182051440.010
regulation of apoptotic signaling pathwayGO:20012331750.010
regulation of map kinase activityGO:00434051080.010
tissue morphogenesisGO:0048729960.010
cellular response to growth factor stimulusGO:00713631970.010
cell cell signalingGO:00072671550.010

PI4KA disease predictions

DiseaseDO term IDSizeProbabilityFunc Analog Org
central nervous system diseaseDOID:3311860.029
nervous system diseaseDOID:8634310.029
neurodegenerative diseaseDOID:12891020.021
disease of metabolismDOID:00146672950.019
musculoskeletal system diseaseDOID:172230.019
eye and adnexa diseaseDOID:14921500.016
sensory system diseaseDOID:00501552030.016
eye diseaseDOID:56141490.016
muscular diseaseDOID:00800001140.015
muscle tissue diseaseDOID:661130.014
retinal diseaseDOID:56791180.013
retinal degenerationDOID:8466890.013
inherited metabolic disorderDOID:6552420.012
disease of cellular proliferationDOID:145661740.012
organ system cancerDOID:00506861640.012
cancerDOID:1621670.012
cardiovascular system diseaseDOID:12871060.011
myopathyDOID:4231040.011
disease of mental healthDOID:150700.011
brain diseaseDOID:936730.011