Homo sapiens

29 known processes

KL

klotho

KL biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
system processGO:00030083490.097
cellular amino acid metabolic processGO:00065201160.096
amine metabolic processGO:0009308440.087
regulation of cellular amino acid metabolic processGO:000652160.086
regulation of cellular amine metabolic processGO:0033238110.085
ion transmembrane transportGO:00342203380.084
purine ribonucleoside metabolic processGO:00461284370.080
cation transportGO:00068123310.079
cellular amine metabolic processGO:0044106410.073
nervous system developmentGO:00073992930.070
regulation of cellular ketone metabolic processGO:0010565500.069
positive regulation of cellular amino acid metabolic processGO:004576430.069
purine containing compound catabolic processGO:00725234110.067
small gtpase mediated signal transductionGO:0007264780.066
cellular ketone metabolic processGO:0042180800.066
inorganic ion transmembrane transportGO:00986602310.065
positive regulation of cellular amine metabolic processGO:003324070.064
organophosphate catabolic processGO:00464344300.064
glycosyl compound catabolic processGO:19016584130.063
response to oxygen containing compoundGO:19017003690.062
regulation of locomotionGO:00400123290.062
ras protein signal transductionGO:0007265730.062
inorganic cation transmembrane transportGO:00986621940.060
cell adhesionGO:00071553250.060
post embryonic developmentGO:000979120.059
transmembrane transportGO:00550853990.059
nucleoside phosphate catabolic processGO:19012924120.059
purine nucleoside catabolic processGO:00061523980.058
purine ribonucleotide catabolic processGO:00091544040.058
nucleotide catabolic processGO:00091664080.057
nucleoside catabolic processGO:00091644080.057
ion homeostasisGO:00508012300.057
chemical homeostasisGO:00488783060.057
ribonucleotide catabolic processGO:00092614050.057
positive regulation of nucleotide metabolic processGO:00459812300.056
purine ribonucleoside catabolic processGO:00461303980.055
cation transmembrane transportGO:00986552380.053
positive regulation of transportGO:00510503360.053
purine nucleoside triphosphate catabolic processGO:00091463920.053
lipid metabolic processGO:00066293810.053
ribonucleoside triphosphate metabolic processGO:00091994120.052
biological adhesionGO:00226103310.052
purine ribonucleoside triphosphate catabolic processGO:00092073910.052
ribonucleoside triphosphate catabolic processGO:00092033910.052
purine ribonucleoside triphosphate metabolic processGO:00092054110.052
ribonucleoside catabolic processGO:00424544060.052
nucleoside triphosphate metabolic processGO:00091414220.051
single organism cellular localizationGO:19025803320.049
regulation of nucleotide metabolic processGO:00061402690.049
purine nucleotide catabolic processGO:00061954050.048
nucleoside triphosphate catabolic processGO:00091433940.048
cellular response to endogenous stimulusGO:00714953360.048
actin filament based processGO:00300292240.048
purine nucleoside triphosphate metabolic processGO:00091444120.048
regulation of cell migrationGO:00303342890.048
locomotory behaviorGO:000762610.048
guanosine containing compound metabolic processGO:19010682440.047
regulation of cell motilityGO:20001452990.046
positive regulation of hydrolase activityGO:00513453310.046
metal ion transportGO:00300012720.046
cardiovascular system developmentGO:00723582620.045
positive regulation of purine nucleotide metabolic processGO:19005442270.044
g protein coupled receptor signaling pathwayGO:00071862070.044
gtp catabolic processGO:00061842370.044
metal ion homeostasisGO:00550651690.043
cell developmentGO:00484683280.043
response to abiotic stimulusGO:00096283360.043
positive regulation of catabolic processGO:00098963100.043
regulation of cellular component movementGO:00512703340.042
vesicle mediated transportGO:00161923710.042
secretion by cellGO:00329402260.042
regulation of cell differentiationGO:00455953930.042
cation homeostasisGO:00550801890.042
anion transportGO:00068201610.041
cellular ion homeostasisGO:00068731680.040
cellular response to oxygen containing compoundGO:19017012760.040
secretionGO:00469032540.039
positive regulation of phosphorylationGO:00423273940.039
cellular cation homeostasisGO:00300031630.038
positive regulation of developmental processGO:00510943140.038
regulation of nucleoside metabolic processGO:00091182090.038
multicellular organismal agingGO:001025930.038
circulatory system developmentGO:00723592620.037
gtp metabolic processGO:00460392390.037
cellular chemical homeostasisGO:00550821800.037
positive regulation of protein phosphorylationGO:00019343130.037
determination of adult lifespanGO:000834020.036
regulation of purine nucleotide metabolic processGO:19005422640.036
cell projection organizationGO:00300302520.035
cellular lipid metabolic processGO:00442553030.035
calcium ion homeostasisGO:00550741220.035
cytoplasmic transportGO:00164823790.035
single organism membrane organizationGO:00448022680.034
cellular homeostasisGO:00197251960.034
female gamete generationGO:000729220.034
guanosine containing compound catabolic processGO:19010692390.034
response to organic cyclic compoundGO:00140702040.034
mapk cascadeGO:00001652880.034
regulation of cellular component biogenesisGO:00440872810.034
positive regulation of cell proliferationGO:00082843010.034
neurological system processGO:00508771630.034
cellular divalent inorganic cation homeostasisGO:00725031280.033
cellular metal ion homeostasisGO:00068751460.033
positive regulation of cellular component organizationGO:00511303760.033
signal transduction by phosphorylationGO:00230142970.033
rho protein signal transductionGO:0007266260.033
organonitrogen compound biosynthetic processGO:19015662000.033
regulation of gtpase activityGO:00430871800.032
cellular component morphogenesisGO:00329893140.032
segmentationGO:003528240.032
divalent inorganic cation homeostasisGO:00725071360.032
carbohydrate derivative biosynthetic processGO:19011372070.032
positive regulation of cellular catabolic processGO:00313312840.032
memoryGO:000761330.032
negative regulation of protein metabolic processGO:00512483910.031
positive regulation of nucleoside metabolic processGO:00459791860.031
oogenesisGO:004847720.031
negative regulation of catalytic activityGO:00430863350.031
regulation of gtp catabolic processGO:00331241800.031
regulation of ion transportGO:00432691890.031
positive regulation of synaptic transmissionGO:005080640.031
enzyme linked receptor protein signaling pathwayGO:00071673030.031
regulation of mapk cascadeGO:00434082620.031
membrane organizationGO:00610242920.030
immune responseGO:00069553070.030
defense responseGO:00069523150.030
Rat
negative regulation of cellular component organizationGO:00511292350.029
positive regulation of purine nucleotide catabolic processGO:00331231850.029
negative regulation of multicellular organismal processGO:00512413170.029
cellular calcium ion homeostasisGO:00068741170.029
cell morphogenesisGO:00009022960.029
regulation of anatomical structure morphogenesisGO:00226032860.029
regulation of secretionGO:00510461940.029
positive regulation of nucleotide catabolic processGO:00308131850.028
regulation of transferase activityGO:00513383550.028
regulation of protein localizationGO:00328802960.028
negative regulation of phosphate metabolic processGO:00459362670.028
regulation of secretion by cellGO:19035301770.028
organophosphate biosynthetic processGO:00904071630.028
regulation of purine nucleotide catabolic processGO:00331212050.028
negative regulation of cellular protein metabolic processGO:00322693530.028
hindbrain developmentGO:003090230.028
negative regulation of phosphorus metabolic processGO:00105632670.028
regulation of protein kinase activityGO:00458592890.028
response to external biotic stimulusGO:00432072610.028
generation of neuronsGO:00486991520.028
response to other organismGO:00517072610.028
anatomical structure formation involved in morphogenesisGO:00486462840.028
regulation of nucleotide catabolic processGO:00308112050.028
regulation of small gtpase mediated signal transductionGO:00510561560.028
nitrogen compound transportGO:00717051910.027
regulation of kinase activityGO:00435493140.027
muscle system processGO:0003012810.027
positive regulation of gtpase activityGO:00435471660.027
regulation of cytokine productionGO:00018172320.027
negative regulation of transportGO:00510511760.027
negative regulation of cell deathGO:00605483450.027
response to nitrogen compoundGO:19016981840.026
blood vessel developmentGO:00015681720.026
positive regulation of transferase activityGO:00513472270.026
cell fate determinationGO:000170930.026
regulation of ras protein signal transductionGO:00465781550.026
positive regulation of gtp catabolic processGO:00331261660.026
monovalent inorganic cation transportGO:00156721280.026
cellular response to dna damage stimulusGO:00069743790.026
lipid biosynthetic processGO:00086101770.026
negative regulation of developmental processGO:00510932470.026
actin cytoskeleton organizationGO:00300362070.026
response to lipidGO:00339932060.026
regulation of response to external stimulusGO:00321012220.025
regulation of membrane potentialGO:0042391950.025
neuron differentiationGO:00301821380.025
cellular response to growth factor stimulusGO:00713631970.025
regulation of proteolysisGO:00301622930.025
negative regulation of apoptotic processGO:00430663160.025
neuromuscular junction developmentGO:000752830.025
muscle contractionGO:0006936730.025
epithelium developmentGO:00604292270.025
carbohydrate metabolic processGO:00059752070.025
regulation of protein transportGO:00512232130.024
motor neuron axon guidanceGO:000804520.024
growthGO:00400072020.024
cytosolic calcium ion homeostasisGO:0051480890.024
cardiac muscle cell contractionGO:008600340.024
response to hormoneGO:00097251750.024
positive regulation of cell differentiationGO:00455972110.024
response to organonitrogen compoundGO:00102431560.024
regulation of cellular response to stressGO:00801352440.024
protein catabolic processGO:00301633250.024
negative regulation of programmed cell deathGO:00430693210.024
associative learningGO:000830610.024
regulation of establishment of protein localizationGO:00702012420.024
neurogenesisGO:00220081690.023
endomembrane system organizationGO:00102561960.023
regenerationGO:003109940.023
circulatory system processGO:00030131130.023
regulation of cell cycleGO:00517263930.023
positive regulation of ras gtpase activityGO:00323201170.023
protein localization to organelleGO:00333652800.023
regulation of cell developmentGO:00602841610.023
mitotic cell cycleGO:00002783260.023
vasculature developmentGO:00019441810.022
cellular response to nitrogen compoundGO:19016991440.022
central nervous system developmentGO:00074171230.022
cytokine productionGO:00018162470.022
positive regulation of immune system processGO:00026842830.022
positive regulation of cellular component movementGO:00512721810.022
blood circulationGO:00080151130.022
single organism cell adhesionGO:00986021790.022
positive regulation of kinase activityGO:00336742040.022
regulation of ras gtpase activityGO:00323181280.022
anterior posterior axis specificationGO:000994820.022
cell cell signalingGO:00072671550.022
positive regulation of mapk cascadeGO:00434101900.021
response to biotic stimulusGO:00096072760.021
regulation of synaptic plasticityGO:004816730.021
negative regulation of transcription from rna polymerase ii promoterGO:00001222810.021
single organism carbohydrate metabolic processGO:00447231930.021
cellular macromolecule catabolic processGO:00442653800.021
negative regulation of cell proliferationGO:00082852280.021
regulation of intracellular transportGO:00323861950.021
anion transmembrane transportGO:0098656760.021
rhythmic behaviorGO:000762220.021
organ formationGO:004864530.021
blastoderm segmentationGO:000735020.021
adult locomotory behaviorGO:000834410.021
response to woundingGO:00096111680.020
sequestering of metal ionGO:0051238240.020
negative regulation of cell migrationGO:00303361020.020
positive regulation of cytokine productionGO:00018191670.020
negative regulation of hydrolase activityGO:00513461820.020
dephosphorylationGO:00163112090.020
purine ribonucleotide biosynthetic processGO:0009152790.020
negative regulation of cellular amine metabolic processGO:003323930.020
negative regulation of cellular amino acid metabolic processGO:004576320.020
regulation of transmembrane transportGO:00347621390.020
oxidation reduction processGO:00551143960.020
circadian behaviorGO:004851220.020
blood vessel morphogenesisGO:00485141620.020
sequestering of calcium ionGO:0051208170.019
organic anion transportGO:00157111030.019
cellular macromolecular complex assemblyGO:00346223240.019
regulation of cytoskeleton organizationGO:00514931770.019
cyclic purine nucleotide metabolic processGO:0052652600.019
positive regulation of locomotionGO:00400171860.019
regulation of actin filament based processGO:00329701410.019
organic hydroxy compound metabolic processGO:19016151470.019
positive regulation of cell deathGO:00109422630.019
mitotic cell cycle processGO:19030472860.019
transmembrane receptor protein tyrosine kinase signaling pathwayGO:00071691810.019
cyclic nucleotide metabolic processGO:0009187820.019
positive regulation of protein kinase activityGO:00458601900.019
regulation of ion transmembrane transportGO:00347651320.019
regulation of cell adhesionGO:00301551660.019
positive regulation of cell migrationGO:00303351720.019
compound eye developmentGO:004874910.019
protein modification by small protein conjugationGO:00324463420.019
lung alveolus developmentGO:004828640.019
response to growth factorGO:00708482050.019
protein maturationGO:00516042330.019
regulation of cell cycle processGO:00105642660.019
protein processingGO:00164852260.019
intracellular protein transportGO:00068862700.019
regulation of sequence specific dna binding transcription factor activityGO:00510902110.019
positive regulation of secretionGO:00510471160.019
spinal cord developmentGO:002151040.019
protein ubiquitinationGO:00165673140.019
negative regulation of protein modification processGO:00314002000.019
positive regulation of apoptotic processGO:00430652460.018
small molecule biosynthetic processGO:00442831570.018
peripheral nervous system developmentGO:000742220.018
innate immune responseGO:00450871780.018
maintenance of locationGO:00512351120.018
nucleotide biosynthetic processGO:00091651090.018
peptidyl tyrosine phosphorylationGO:00181081700.018
limbic system developmentGO:002176130.018
divalent inorganic cation transportGO:00725111580.018
nucleoside phosphate biosynthetic processGO:19012931090.018
angiogenesisGO:00015251470.018
calcium ion transportGO:00068161470.018
long term memoryGO:000761620.018
peptidyl tyrosine modificationGO:00182121700.018
cellular response to organonitrogen compoundGO:00714171240.018
neuron developmentGO:00486661130.018
reactive nitrogen species metabolic processGO:200105730.018
hemopoiesisGO:00300971800.018
actin filament based movementGO:0030048170.018
apoptotic signaling pathwayGO:00971902680.018
regulation of hormone levelsGO:00108171250.018
negative regulation of intracellular signal transductionGO:19025321830.018
positive regulation of cellular component biogenesisGO:00440891580.018
metencephalon developmentGO:002203720.018
oocyte differentiationGO:000999420.018
protein localization to membraneGO:00726571600.018
morphogenesis of embryonic epitheliumGO:001633140.018
oocyte developmentGO:004859910.017
nerve developmentGO:002167540.017
positive regulation of secretion by cellGO:19035321080.017
regulation of homeostatic processGO:00328441210.017
reactive oxygen species biosynthetic processGO:190340940.017
epithelial cell differentiationGO:00308551410.017
positive regulation of organelle organizationGO:00106381950.017
ribonucleotide biosynthetic processGO:0009260810.017
head developmentGO:00603221080.017
inner ear morphogenesisGO:004247240.017
regulation of growthGO:00400081650.017
second messenger mediated signalingGO:0019932780.017
potassium ion transmembrane transportGO:0071805600.017
positive regulation of cell motilityGO:20001471770.017
spermatid differentiationGO:004851540.017
actin mediated cell contractionGO:0070252120.017
somatic stem cell maintenanceGO:003501940.017
photoreceptor cell differentiationGO:004653020.017
chromatin organizationGO:00063253510.017
ribonucleoside monophosphate metabolic processGO:00091611870.017
regulation of system processGO:00440571010.017
protein targetingGO:00066051870.017
negative regulation of phosphorylationGO:00423261740.017
purine ribonucleoside monophosphate metabolic processGO:00091671860.017
positive regulation of programmed cell deathGO:00430682490.017
negative regulation of cell cycleGO:00457861930.017
multicellular organismal response to stressGO:003355510.017
cell growthGO:00160491600.017
hematopoietic or lymphoid organ developmentGO:00485341860.016
immune system developmentGO:00025201950.016
cellular protein catabolic processGO:00442572610.016
tripartite regional subdivisionGO:000735120.016
negative regulation of synaptic transmissionGO:005080520.016
establishment of protein localization to organelleGO:00725941720.016
histone modificationGO:00165702510.016
regulation of transporter activityGO:0032409820.016
glycerolipid metabolic processGO:00464861070.016
cell substrate adhesionGO:00315891320.016
positive regulation of cytosolic calcium ion concentrationGO:0007204820.016
regulation of vesicle mediated transportGO:00606271300.016
startle responseGO:000196430.016
alcohol metabolic processGO:00060661140.016
response to axon injuryGO:004867810.016
reactive oxygen species metabolic processGO:0072593750.016
cgmp catabolic processGO:004606930.016
adenylate cyclase inhibiting adrenergic receptor signaling pathwayGO:007188110.016
regulation of protein serine threonine kinase activityGO:00719001790.016
camp metabolic processGO:0046058610.016
regulation of neural precursor cell proliferationGO:200017740.016
regulation of immune responseGO:00507762010.016
purine nucleoside monophosphate metabolic processGO:00091261860.016
single organismal cell cell adhesionGO:00163371480.016
matingGO:000761810.016
purine nucleotide biosynthetic processGO:0006164840.016
regulation of cell growthGO:00015581350.016
nucleoside monophosphate metabolic processGO:00091231910.016
sensory perception of smellGO:000760820.016
divalent metal ion transportGO:00708381520.016
chromatin modificationGO:00165682980.016
specification of organ identityGO:001009230.016
cerebellum developmentGO:002154920.016
regulation of reactive oxygen species biosynthetic processGO:190342630.015
ossificationGO:00015031210.015
regulation of protein catabolic processGO:00421761550.015
ribose phosphate biosynthetic processGO:0046390820.015
purine containing compound biosynthetic processGO:0072522880.015
cell part morphogenesisGO:00329901370.015
embryonic epithelial tube formationGO:000183840.015
spermatid developmentGO:000728640.015
regulation of cell morphogenesisGO:00226041530.015
striated muscle contractionGO:0006941520.015
response to cytokineGO:00340972320.015
organ morphogenesisGO:00098871470.015
atp metabolic processGO:00460341760.015
regulation of transmembrane transporter activityGO:0022898740.015
nuclear transportGO:00511691790.015
protein oligomerizationGO:00512591730.015
negative regulation of organelle organizationGO:00106391260.015
microtubule based processGO:00070172100.015
potassium ion transportGO:0006813620.015
cellular response to cytokine stimulusGO:00713451810.015
anterior posterior axis specification embryoGO:000859520.015
regulation of cytoplasmic transportGO:19036491490.015
neuron projection developmentGO:00311751060.015
negative regulation of cell differentiationGO:00455961710.015
taxisGO:00423301570.015
somitogenesisGO:000175620.015
covalent chromatin modificationGO:00165692540.015
lipid transportGO:0006869900.015
positive regulation of protein transportGO:00512221350.015
positive regulation of cell developmentGO:0010720920.015
endocytosisGO:00068971590.015
brain developmentGO:0007420970.015
neuroblast proliferationGO:000740540.014
regulation of response to woundingGO:19030341010.014
cyclic nucleotide biosynthetic processGO:0009190610.014
cellular protein complex assemblyGO:00436231880.014
proteolysis involved in cellular protein catabolic processGO:00516032440.014
forebrain generation of neuronsGO:002187230.014
posttranscriptional regulation of gene expressionGO:00106082130.014
camp biosynthetic processGO:0006171470.014
regulation of ion transmembrane transporter activityGO:0032412720.014
cellular response to organic cyclic compoundGO:00714071270.014
organic hydroxy compound transportGO:0015850630.014
adenylate cyclase modulating g protein coupled receptor signaling pathwayGO:0007188430.014
inorganic anion transmembrane transportGO:0098661470.014
cell projection morphogenesisGO:00488581290.014
regulation of endopeptidase activityGO:00525481700.014
i kappab kinase nf kappab signalingGO:00072491660.014
thymus developmentGO:004853830.014
regulation of camp biosynthetic processGO:0030817450.014
salivary gland morphogenesisGO:000743540.014
wnt signaling pathwayGO:00160551560.014
tissue migrationGO:00901301190.014
negative regulation of cellular component movementGO:00512711060.014
neurotransmitter secretionGO:000726940.014
monocarboxylic acid metabolic processGO:00327871850.014
cell divisionGO:00513011680.014
response to bacteriumGO:00096171440.014
g protein coupled receptor signaling pathway coupled to cyclic nucleotide second messengerGO:0007187430.014
regulation of purine nucleotide biosynthetic processGO:1900371500.014
negative regulation of protein phosphorylationGO:00019331400.014
actin filament organizationGO:00070151280.014
regulation of peptidase activityGO:00525471800.014
cardiac muscle contractionGO:0060048340.014
regulation of cell activationGO:00508651250.014
regulation of cyclic nucleotide biosynthetic processGO:0030802490.014
visual behaviorGO:000763220.014
chemotaxisGO:00069351570.014
cell activationGO:00017752130.014
behaviorGO:00076101120.014
morphogenesis of a polarized epitheliumGO:000173830.014
ameboidal type cell migrationGO:00016671350.014
regulation of actin cytoskeleton organizationGO:00329561160.014
lipid localizationGO:00108761060.014
regulation of mitotic cell cycleGO:00073461890.013
glycoprotein metabolic processGO:00091001100.013
plasma membrane organizationGO:00070091150.013
establishment of protein localization to membraneGO:00901501210.013
vasodilationGO:004231140.013
lipid catabolic processGO:0016042840.013
epithelial cell migrationGO:00106311190.013
fatty acid metabolic processGO:00066311150.013
regulation of protein processingGO:00706131500.013
regulation of multi organism processGO:00439001570.013
sensory perception of painGO:001923340.013
non canonical wnt signaling pathway via mapk cascadeGO:003803040.013
cellular potassium ion transportGO:0071804600.013
regulation of i kappab kinase nf kappab signalingGO:00431221620.013
regulation of protein maturationGO:19033171500.013
symbiosis encompassing mutualism through parasitismGO:00444031560.013
regulation of axon guidanceGO:190266730.013
positive regulation of cyclic nucleotide biosynthetic processGO:0030804380.013
negative regulation of blood pressureGO:004577630.013
regulation of camp metabolic processGO:0030814520.013
regulation of cell projection organizationGO:00313441070.013
microtubule cytoskeleton organizationGO:00002261760.013
negative regulation of locomotionGO:00400131180.013
epithelium migrationGO:00901321190.013
organelle assemblyGO:00709251760.013
immune effector processGO:00022521590.013
positive regulation of purine nucleotide biosynthetic processGO:1900373380.013
cellular response to glucocorticoid stimulusGO:007138540.013
proteasomal protein catabolic processGO:00104981760.013
cofactor metabolic processGO:0051186870.013
sex determinationGO:000753030.013
response to decreased oxygen levelsGO:0036293960.013
nucleocytoplasmic transportGO:00069131760.013
transmembrane receptor protein serine threonine kinase signaling pathwayGO:00071781250.013
rna interferenceGO:001624640.013
tube developmentGO:00352951250.013
pituitary gland developmentGO:002198320.013
response to fungusGO:000962040.013
multi organism cellular processGO:00447641560.013
hindlimb morphogenesisGO:003513720.013
forelimb morphogenesisGO:003513640.013
stem cell divisionGO:001714520.013

KL disease predictions

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of metabolismDOID:00146672950.036
kidney diseaseDOID:557360.033
renal tubular transport diseaseDOID:447110.033
urinary system diseaseDOID:18400.033
inherited metabolic disorderDOID:6552420.026
nervous system diseaseDOID:8634310.025
sensory system diseaseDOID:00501552030.025
musculoskeletal system diseaseDOID:172230.023
cancerDOID:1621670.020
disease of cellular proliferationDOID:145661740.020
immune system diseaseDOID:29141550.020
central nervous system diseaseDOID:3311860.019
cardiovascular system diseaseDOID:12871060.019
organ system cancerDOID:00506861640.019
eye and adnexa diseaseDOID:14921500.018
eye diseaseDOID:56141490.017
muscle tissue diseaseDOID:661130.014
muscular diseaseDOID:00800001140.014
connective tissue diseaseDOID:651090.014
myopathyDOID:4231040.013
brain diseaseDOID:936730.013