Homo sapiens

165 known processes

RAD50

RAD50 homolog (S. cerevisiae)

(Aliases: RAD502,hRad50,NBSLD)

RAD50 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
cellular response to dna damage stimulusGO:00069743791.000
dna repairGO:00062811980.997
dna double strand break processingGO:0000729100.994
nucleotide excision repairGO:0006289310.987
regulation of dna metabolic processGO:00510521530.986
double strand break repairGO:00063021010.980
regulation of protein autophosphorylationGO:0031952150.980
g2 dna damage checkpointGO:0031572260.960
dna damage checkpointGO:0000077680.930
meiosis iGO:000712740.929
double strand break repair via single strand annealingGO:004500240.895
cell cycle checkpointGO:00000751170.884
double strand break repair via homologous recombinationGO:0000724500.883
isotype switchingGO:004519030.877
nucleoside phosphate catabolic processGO:19012924120.869
negative regulation of mitotic cell cycleGO:00459301020.866
dna catabolic process exonucleolyticGO:0000738170.856
mitotic dna damage checkpointGO:0044773280.818
dna geometric changeGO:0032392320.807
dna integrity checkpointGO:0031570710.800
regulation of cell cycleGO:00517263930.780
covalent chromatin modificationGO:00165692540.760
negative regulation of cell cycle phase transitionGO:1901988890.751
nucleotide catabolic processGO:00091664080.747
ribonucleoside catabolic processGO:00424544060.741
negative regulation of mitotic cell cycle phase transitionGO:1901991850.726
response to radiationGO:00093141510.722
negative regulation of dna replicationGO:0008156290.719
mitotic cell cycle checkpointGO:0007093680.717
somatic recombination of immunoglobulin gene segmentsGO:001644740.714
dna duplex unwindingGO:0032508300.697
dna catabolic processGO:0006308490.697
regulation of meiotic cell cycleGO:005144540.696
cell cycle phase transitionGO:00447701730.691
positive regulation of protein phosphorylationGO:00019343130.686
signal transduction in response to dna damageGO:0042770570.677
positive regulation of phosphorylationGO:00423273940.657
purine ribonucleoside catabolic processGO:00461303980.648
intrinsic apoptotic signaling pathwayGO:00971931270.647
regulation of cell cycle phase transitionGO:19019871260.625
somatic recombination of immunoglobulin genes involved in immune responseGO:000220430.607
regulation of mitotic cell cycleGO:00073461890.600
positive regulation of telomere maintenanceGO:003220640.598
dna damage induced protein phosphorylationGO:000697550.585
negative regulation of cell cycleGO:00457861930.564
cellular macromolecule catabolic processGO:00442653800.561
somatic diversification of immune receptorsGO:000220080.560
regulation of mitotic cell cycle phase transitionGO:19019901180.548
atp catabolic processGO:00062001570.540
negative regulation of cell cycle processGO:00109481210.539
chromosome segregationGO:00070591140.533
Worm
mitotic dna integrity checkpointGO:0044774300.530
telomere maintenanceGO:0000723320.519
intra s dna damage checkpointGO:003157340.515
purine nucleotide catabolic processGO:00061954050.491
purine nucleoside monophosphate catabolic processGO:00091281580.485
meiotic chromosome segregationGO:004513240.483
Worm
dna conformation changeGO:00711031130.481
nucleic acid phosphodiester bond hydrolysisGO:00903051020.469
mitotic cell cycle phase transitionGO:00447721620.468
purine ribonucleoside monophosphate catabolic processGO:00091691580.445
reciprocal meiotic recombinationGO:000713140.443
purine nucleoside catabolic processGO:00061523980.440
blastocyst developmentGO:000182430.423
cellular response to ionizing radiationGO:0071479320.417
ribonucleotide catabolic processGO:00092614050.412
mitotic cell cycleGO:00002783260.409
mitotic cell cycle processGO:19030472860.408
anatomical structure homeostasisGO:00602491000.402
recombinational repairGO:0000725500.393
replication fork processingGO:0031297130.385
nuclear divisionGO:00002801280.385
Worm
regulation of cell cycle processGO:00105642660.376
positive regulation of dna replicationGO:0045740350.375
neuromuscular process controlling balanceGO:005088570.347
purine nucleoside triphosphate metabolic processGO:00091444120.340
g2 m transition of mitotic cell cycleGO:0000086410.333
positive regulation of transferase activityGO:00513472270.329
regulation of dna replicationGO:0006275680.316
nucleoside triphosphate catabolic processGO:00091433940.315
telomere cappingGO:001623350.303
Fly
response to abiotic stimulusGO:00096283360.302
regulation of response to dna damage stimulusGO:2001020940.290
regulation of proteolysisGO:00301622930.288
positive regulation of kinase activityGO:00336742040.276
ribonucleoside monophosphate catabolic processGO:00091581580.273
positive regulation of meiotic cell cycleGO:005144620.271
regulation of kinase activityGO:00435493140.270
somatic diversification of immunoglobulinsGO:001644560.269
organelle fissionGO:00482851490.256
Worm
dna damage response signal transduction by p53 class mediatorGO:0030330440.248
positive regulation of cell cycleGO:00457871400.245
dna dependent dna replicationGO:0006261440.237
regulation of transcription by chromatin organizationGO:003440110.229
response to nitrogen compoundGO:19016981840.219
cardiovascular system developmentGO:00723582620.213
organophosphate catabolic processGO:00464344300.211
signal transduction by phosphorylationGO:00230142970.196
somatic diversification of immunoglobulins involved in immune responseGO:000220830.175
nucleoside catabolic processGO:00091644080.162
mitotic g2 m transition checkpointGO:004481890.153
dna recombinationGO:0006310770.152
negative regulation of cell deathGO:00605483450.150
reciprocal dna recombinationGO:003582540.148
nucleoside monophosphate metabolic processGO:00091231910.147
glycosyl compound catabolic processGO:19016584130.146
regulation of telomere maintenanceGO:0032204130.146
leukocyte differentiationGO:0002521980.141
nucleoside triphosphate metabolic processGO:00091414220.138
signal transduction involved in dna damage checkpointGO:0072422150.138
mismatch repairGO:0006298150.128
cell activation involved in immune responseGO:0002263300.126
leukocyte activation involved in immune responseGO:0002366300.126
cell activationGO:00017752130.125
positive regulation of protein autophosphorylationGO:003195490.125
chromatin modificationGO:00165682980.124
chromatin organizationGO:00063253510.123
ubiquitin dependent protein catabolic processGO:00065112060.123
purine nucleoside triphosphate catabolic processGO:00091463920.123
apoptotic signaling pathwayGO:00971902680.122
regulation of dna endoreduplicationGO:003287550.122
immune system developmentGO:00025201950.112
lipid localizationGO:00108761060.111
interstrand cross link repairGO:003629730.110
system processGO:00030083490.107
regulation of transferase activityGO:00513383550.104
signal transduction involved in mitotic dna integrity checkpointGO:1902403130.103
purine ribonucleotide catabolic processGO:00091544040.103
chordate embryonic developmentGO:0043009340.100
ribonucleoside triphosphate metabolic processGO:00091994120.099
nucleoside monophosphate catabolic processGO:00091251590.099
regulation of dna dependent dna replicationGO:0090329190.097
purine ribonucleoside metabolic processGO:00461284370.097
dna replicationGO:00062601160.097
purine nucleoside monophosphate metabolic processGO:00091261860.095
ribonucleoside monophosphate metabolic processGO:00091611870.091
purine ribonucleoside triphosphate metabolic processGO:00092054110.091
non recombinational repairGO:0000726140.090
adaptive immune responseGO:0002250490.090
cellular response to abiotic stimulusGO:00712141170.090
positive regulation of cellular component organizationGO:00511303760.087
mrna processingGO:00063971330.086
atp metabolic processGO:00460341760.084
mitotic g2 dna damage checkpointGO:000709570.083
male gonad developmentGO:0008584230.082
leukocyte activationGO:00453211640.080
double strand break repair via nonhomologous end joiningGO:0006303100.078
negative regulation of g2 m transition of mitotic cell cycleGO:001097290.074
regulation of protein catabolic processGO:00421761550.074
positive regulation of cellular component biogenesisGO:00440891580.072
intrinsic apoptotic signaling pathway in response to dna damageGO:0008630500.071
lymphocyte mediated immunityGO:0002449480.070
telomere organizationGO:0032200330.070
dna catabolic process endonucleolyticGO:0000737370.069
ion homeostasisGO:00508012300.067
immunoglobulin productionGO:0002377120.065
histone modificationGO:00165702510.063
fatty acid biosynthetic processGO:0006633460.062
cellular homeostasisGO:00197251960.061
production of molecular mediator of immune responseGO:0002440370.061
inorganic ion transmembrane transportGO:00986602310.060
neurological system processGO:00508771630.059
negative regulation of cell proliferationGO:00082852280.059
positive regulation of dna damage response signal transduction by p53 class mediatorGO:004351780.058
peptidyl serine modificationGO:00182091060.057
maintenance of locationGO:00512351120.057
histone h3 k4 methylationGO:0051568270.056
rna processingGO:00063962550.055
immune responseGO:00069553070.055
neuromuscular processGO:0050905150.055
ribonucleoside triphosphate catabolic processGO:00092033910.054
regulation of helicase activityGO:005109580.054
protein maturationGO:00516042330.053
telomere maintenance via recombinationGO:000072240.051
Fly
response to gamma radiationGO:0010332140.050
mrna metabolic processGO:00160711750.049
positive regulation of chromosome organizationGO:2001252410.049
nucleosome assemblyGO:0006334500.048
cellular response to light stimulusGO:0071482340.048
leukocyte mediated immunityGO:0002443590.048
development of primary male sexual characteristicsGO:0046546230.046
regulation of protein kinase activityGO:00458592890.046
negative regulation of protein metabolic processGO:00512483910.046
immune effector processGO:00022521590.046
regulation of cellular component biogenesisGO:00440872810.046
regulation of neuron apoptotic processGO:0043523350.046
organelle localizationGO:0051640840.044
dna replication independent nucleosome organizationGO:0034724270.044
meiotic cell cycleGO:0051321130.043
Worm
oocyte differentiationGO:000999420.043
protein homooligomerizationGO:00512601000.043
meiotic nuclear divisionGO:0007126100.041
Worm
immunoglobulin production involved in immunoglobulin mediated immune responseGO:000238150.041
jnk cascadeGO:0007254800.041
intracellular protein transportGO:00068862700.041
purine ribonucleoside monophosphate metabolic processGO:00091671860.041
peptidyl serine phosphorylationGO:00181051010.041
neuron deathGO:0070997650.040
sister chromatid cohesionGO:0007062240.040
determination of adult lifespanGO:000834020.040
cation homeostasisGO:00550801890.039
female gamete generationGO:000729220.037
oogenesisGO:004847720.037
epithelial cell differentiationGO:00308551410.037
regulation of double strand break repairGO:2000779220.036
central nervous system developmentGO:00074171230.036
response to uvGO:0009411730.036
negative regulation of developmental processGO:00510932470.035
cell projection organizationGO:00300302520.035
somatic cell dna recombinationGO:001644460.035
negative regulation of dna dependent dna replicationGO:200010490.035
lipid storageGO:0019915280.034
histone methylationGO:0016571600.034
negative regulation of cellular amino acid metabolic processGO:004576320.033
regulation of dna repairGO:0006282470.033
monocarboxylic acid biosynthetic processGO:0072330670.033
neuron apoptotic processGO:0051402390.032
cellular ion homeostasisGO:00068731680.032
response to caffeineGO:003100030.032
regulation of protein maturationGO:19033171500.032
circulatory system developmentGO:00723592620.031
rna splicingGO:00083801310.031
purine ribonucleoside triphosphate catabolic processGO:00092073910.030
mitochondrion organizationGO:00070051560.030
regulation of cellular response to stressGO:00801352440.029
purine containing compound catabolic processGO:00725234110.029
positive regulation of transcription initiation from rna polymerase ii promoterGO:006026140.029
somitogenesisGO:000175620.029
carboxylic acid biosynthetic processGO:0046394970.028
protein polyubiquitinationGO:00002091100.028
dna replication independent nucleosome assemblyGO:0006336270.028
response to inorganic substanceGO:00100351270.028
negative regulation of cellular protein catabolic processGO:1903363380.027
organelle assemblyGO:00709251760.027
actin filament based processGO:00300292240.027
lymphocyte activationGO:00466491330.027
negative regulation of phosphorus metabolic processGO:00105632670.027
response to ionizing radiationGO:0010212650.027
response to organic cyclic compoundGO:00140702040.026
enzyme linked receptor protein signaling pathwayGO:00071673030.025
protein deubiquitinationGO:0016579790.025
positive regulation of homeostatic processGO:0032846470.025
negative regulation of apoptotic processGO:00430663160.025
regulation of anatomical structure morphogenesisGO:00226032860.025
embryo developmentGO:00097901230.024
Worm
single organism cellular localizationGO:19025803320.024
cell type specific apoptotic processGO:00972851250.024
positive regulation of growthGO:0045927580.024
cell part morphogenesisGO:00329901370.024
cellular amino acid metabolic processGO:00065201160.024
cellular chemical homeostasisGO:00550821800.024
cellular lipid metabolic processGO:00442553030.024
response to cytokineGO:00340972320.023
intrinsic apoptotic signaling pathway in response to dna damage by p53 class mediatorGO:0042771230.023
modification dependent macromolecule catabolic processGO:00436322120.022
protein processingGO:00164852260.022
lymphocyte activation involved in immune responseGO:0002285200.022
negative regulation of cellular amine metabolic processGO:003323930.022
dna dependent dna replication maintenance of fidelityGO:0045005140.022
negative regulation of dna endoreduplicationGO:003287650.022
lipid metabolic processGO:00066293810.021
positive regulation of hydrolase activityGO:00513453310.021
cell cycle dna replicationGO:0044786110.021
ion transmembrane transportGO:00342203380.021
peptidyl threonine modificationGO:0018210450.021
cellular protein catabolic processGO:00442572610.021
response to oxygen containing compoundGO:19017003690.021
regulation of g2 m transition of mitotic cell cycleGO:0010389200.021
regulation of proteasomal ubiquitin dependent protein catabolic processGO:0032434710.021
b cell activationGO:0042113330.020
small gtpase mediated signal transductionGO:0007264780.020
reproductionGO:0000003630.020
Worm
transmembrane transportGO:00550853990.020
regulation of lymphocyte activationGO:00512491030.020
negative regulation of programmed cell deathGO:00430693210.020
regulation of carbohydrate metabolic processGO:0006109540.020
histone phosphorylationGO:0016572160.020
response to metal ionGO:0010038840.019
cell morphogenesisGO:00009022960.019
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domainsGO:0002460400.019
growthGO:00400072020.019
spindle organizationGO:0007051530.019
nuclear exportGO:0051168690.019
base excision repairGO:0006284210.019
cellular metal ion homeostasisGO:00068751460.019
regulation of establishment of protein localizationGO:00702012420.019
chemical homeostasisGO:00488783060.019
vasculature developmentGO:00019441810.018
compound eye developmentGO:004874910.018
anatomical structure formation involved in morphogenesisGO:00486462840.018
mitotic recombinationGO:000631280.018
response to purine containing compoundGO:0014074400.018
proteolysis involved in cellular protein catabolic processGO:00516032440.018
cilium morphogenesisGO:0060271750.018
action potentialGO:0001508340.018
positive regulation of dna metabolic processGO:0051054730.018
maintenance of dna repeat elementsGO:004357040.018
negative regulation of organelle organizationGO:00106391260.017
cellular cation homeostasisGO:00300031630.017
protein alkylationGO:0008213740.017
positive regulation of reactive oxygen species biosynthetic processGO:190342820.017
morphogenesis of an epitheliumGO:0002009600.017
glycerolipid biosynthetic processGO:0045017510.017
signal transduction by p53 class mediatorGO:0072331720.017
positive regulation of organelle organizationGO:00106381950.017
trna processingGO:0008033230.017
negative regulation of cellular catabolic processGO:0031330830.016
regulation of homeostatic processGO:00328441210.016
cellular macromolecular complex assemblyGO:00346223240.016
negative regulation of proteolysisGO:00458611320.016
positive regulation of protein localization to nucleusGO:1900182480.016
postreplication repairGO:0006301120.016
gtp catabolic processGO:00061842370.016
regulation of meiosisGO:004002030.016
negative regulation of epithelial cell proliferationGO:0050680480.016
negative regulation of vasculature developmentGO:1901343430.016
mapk cascadeGO:00001652880.016
cell projection morphogenesisGO:00488581290.016
microtubule cytoskeleton organizationGO:00002261760.016
regulation of cysteine type endopeptidase activity involved in apoptotic processGO:00432811160.015
cellular amine metabolic processGO:0044106410.015
blastoderm segmentationGO:000735020.015
negative regulation of protein processingGO:00109551420.015
signal transduction involved in mitotic cell cycle checkpointGO:0072413130.015
establishment of protein localization to organelleGO:00725941720.015
response to organonitrogen compoundGO:00102431560.015
cellular component assembly involved in morphogenesisGO:0010927730.015
phosphatidylinositol 3 phosphate biosynthetic processGO:003609230.015
mitotic sister chromatid segregationGO:0000070530.015
microtubule based processGO:00070172100.015
embryo development ending in birth or egg hatchingGO:0009792340.015
Worm
segmentationGO:003528240.015
regulation of cellular ketone metabolic processGO:0010565500.015
cellular carbohydrate metabolic processGO:0044262840.015
proteasome mediated ubiquitin dependent protein catabolic processGO:00431611560.015
regenerationGO:003109940.014
histone h2a phosphorylationGO:199016430.014
negative regulation of neuron apoptotic processGO:0043524230.014
organic acid biosynthetic processGO:0016053970.014
cell developmentGO:00484683280.014
posttranscriptional regulation of gene expressionGO:00106082130.014
positive regulation of reactive oxygen species metabolic processGO:2000379240.014
protein autophosphorylationGO:00467771230.014
multicellular organismal agingGO:001025930.014
brain developmentGO:0007420970.014
positive regulation of gtpase activityGO:00435471660.014
negative regulation of immune responseGO:0050777400.014
response to light stimulusGO:0009416870.014
regulation of signal transduction by p53 class mediatorGO:1901796260.013
regulation of viral processGO:00507921030.013
lymphocyte differentiationGO:0030098350.013
epithelial cell developmentGO:0002064340.013
regulation of protein targetingGO:1903533910.013
intrinsic apoptotic signaling pathway by p53 class mediatorGO:0072332370.013
regulation of mononuclear cell proliferationGO:0032944650.013
gtp metabolic processGO:00460392390.013
regulation of cellular protein catabolic processGO:1903362960.013
metal ion homeostasisGO:00550651690.013
translationGO:00064121320.013
regulation of protein transportGO:00512232130.013
amine metabolic processGO:0009308440.013
regulation of protein complex assemblyGO:00432541470.013
negative regulation of catalytic activityGO:00430863350.013
regulation of cell morphogenesisGO:00226041530.013
histone h4 acetylationGO:0043967470.013
regulation of protein bindingGO:0043393660.012
regulation of reactive oxygen species biosynthetic processGO:190342630.012
cellular response to cytokine stimulusGO:00713451810.012
generation of precursor metabolites and energyGO:0006091680.012
negative regulation of lipid metabolic processGO:0045833380.012
regulation of vasculature developmentGO:1901342970.012
positive regulation of cellular amino acid metabolic processGO:004576430.012
protein modification by small protein conjugationGO:00324463420.012
hormone catabolic processGO:004244740.012
protein localization to organelleGO:00333652800.012
negative regulation of immune system processGO:00026831360.012
positive regulation of dna repairGO:0045739250.012
regulation of growthGO:00400081650.012
carbohydrate metabolic processGO:00059752070.012
protein ubiquitinationGO:00165673140.012
regulation of epithelial cell proliferationGO:00506781130.012
reactive nitrogen species metabolic processGO:200105730.012
cell divisionGO:00513011680.012
hindbrain developmentGO:003090230.012
negative regulation of dna metabolic processGO:0051053570.012
single organism reproductive processGO:0044702980.012
neural tube closureGO:000184330.011
signal transduction involved in mitotic dna damage checkpointGO:1902402130.011
regulation of developmental growthGO:0048638300.011
neurogenesisGO:00220081690.011
single organism membrane organizationGO:00448022680.011
cellular divalent inorganic cation homeostasisGO:00725031280.011
macromolecule glycosylationGO:0043413630.011
protein oligomerizationGO:00512591730.011
macromolecule methylationGO:0043414970.011
oocyte developmentGO:004859910.011
cellular response to uvGO:0034644320.010
regulation of protein localizationGO:00328802960.010
dna packagingGO:0006323770.010
actin mediated cell contractionGO:0070252120.010
nuclear transportGO:00511691790.010
cytokinesisGO:0000910960.010
regulation of protein processingGO:00706131500.010
regulation of intracellular transportGO:00323861950.010
positive regulation of response to dna damage stimulusGO:2001022430.010
photoreceptor cell maintenanceGO:0045494130.010
protein dephosphorylationGO:0006470810.010
positive regulation of transportGO:00510503360.010
mitotic dna replication checkpointGO:003331420.010
ras protein signal transductionGO:0007265730.010
regulation of gtpase activityGO:00430871800.010
regulation of purine nucleotide catabolic processGO:00331212050.010
cell projection assemblyGO:00300311260.010

RAD50 disease predictions

DiseaseDO term IDSizeProbabilityFunc Analog Org
immune system diseaseDOID:29141550.880
disease of cellular proliferationDOID:145661740.615
cancerDOID:1621670.615
anemiaDOID:2355550.564
hematopoietic system diseaseDOID:741000.564
aplastic anemiaDOID:12449300.564
bone marrow diseaseDOID:4961310.564
organ system cancerDOID:00506861640.074
congenital hypoplastic anemiaDOID:1342260.034
hematologic cancerDOID:2531360.022
immune system cancerDOID:0060083360.022
nervous system diseaseDOID:8634310.013
central nervous system diseaseDOID:3311860.013
thoracic cancerDOID:5093210.010