Homo sapiens

77 known processes

XRCC5

X-ray repair complementing defective repair in Chinese hamster cells 5 (double-strand-break rejoining)

(Aliases: KARP1,KARP-1,KUB2,NFIV,KU80,FLJ39089,Ku86)

XRCC5 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
cellular response to dna damage stimulusGO:00069743791.000
double strand break repairGO:00063021010.986
nucleic acid phosphodiester bond hydrolysisGO:00903051020.960
post embryonic developmentGO:000979120.958
dna conformation changeGO:00711031130.933
purine ribonucleoside triphosphate metabolic processGO:00092054110.929
somatic diversification of immunoglobulins involved in immune responseGO:000220830.921
purine nucleoside monophosphate catabolic processGO:00091281580.917
regulation of dna metabolic processGO:00510521530.904
purine nucleoside triphosphate metabolic processGO:00091444120.901
chromatin modificationGO:00165682980.891
dna duplex unwindingGO:0032508300.888
dna recombinationGO:0006310770.883
dna catabolic processGO:0006308490.880
covalent chromatin modificationGO:00165692540.879
nucleoside catabolic processGO:00091644080.863
ribonucleoside monophosphate catabolic processGO:00091581580.858
posttranscriptional gene silencingGO:0016441250.856
non recombinational repairGO:0000726140.850
negative regulation of cell cycle phase transitionGO:1901988890.849
dna ligationGO:0006266100.840
chromatin assemblyGO:0031497610.837
chromatin assembly or disassemblyGO:0006333780.836
dna geometric changeGO:0032392320.836
meiosis iGO:000712740.828
ribonucleoside triphosphate metabolic processGO:00091994120.827
dna dependent dna replicationGO:0006261440.818
dna ligation involved in dna repairGO:005110340.814
double strand break repair via nonhomologous end joiningGO:0006303100.810
dna strand elongation involved in dna replicationGO:000627130.804
nucleosome assemblyGO:0006334500.804
purine ribonucleoside catabolic processGO:00461303980.793
nucleoside phosphate catabolic processGO:19012924120.778
chromatin organizationGO:00063253510.778
nucleoside monophosphate metabolic processGO:00091231910.747
atp metabolic processGO:00460341760.743
nucleotide catabolic processGO:00091664080.706
protein autoprocessingGO:001654040.699
purine ribonucleoside monophosphate metabolic processGO:00091671860.687
nucleoside triphosphate catabolic processGO:00091433940.683
immune system developmentGO:00025201950.680
Mouse
nucleoside monophosphate catabolic processGO:00091251590.665
purine nucleoside triphosphate catabolic processGO:00091463920.665
dna damage response detection of dna damageGO:004276930.660
g2 dna damage checkpointGO:0031572260.646
determination of adult lifespanGO:000834020.639
cellular macromolecule catabolic processGO:00442653800.636
reciprocal meiotic recombinationGO:000713140.623
purine containing compound catabolic processGO:00725234110.617
dna strand elongationGO:002261650.607
ribonucleoside catabolic processGO:00424544060.575
positive regulation of cytoplasmic transportGO:1903651820.554
purine nucleoside catabolic processGO:00061523980.547
single strand break repairGO:000001260.534
oogenesisGO:004847720.522
chromatin remodelingGO:0006338550.519
replicative cell agingGO:000130230.514
nucleosome organizationGO:0034728660.511
dna replicationGO:00062601160.506
viral processGO:00160321460.503
embryo developmentGO:00097901230.498
ribonucleoside monophosphate metabolic processGO:00091611870.498
organophosphate catabolic processGO:00464344300.467
base excision repairGO:0006284210.459
nucleoside triphosphate metabolic processGO:00091414220.449
mitotic dna integrity checkpointGO:0044774300.440
negative regulation of mitotic cell cycle phase transitionGO:1901991850.436
glycosyl compound catabolic processGO:19016584130.412
dna packagingGO:0006323770.398
purine ribonucleoside monophosphate catabolic processGO:00091691580.381
nucleus organizationGO:0006997280.379
negative regulation of cell deathGO:00605483450.368
Zebrafish
regulation of viral processGO:00507921030.367
isotype switchingGO:004519030.364
mitotic g2 m transition checkpointGO:004481890.360
negative regulation of dna metabolic processGO:0051053570.348
engulfment of apoptotic cellGO:004365220.339
immunoglobulin production involved in immunoglobulin mediated immune responseGO:000238150.334
nuclear divisionGO:00002801280.334
cellular response to endogenous stimulusGO:00714953360.331
dna repairGO:00062811980.325
multicellular organismal agingGO:001025930.324
v d j recombinationGO:003315130.314
segmentationGO:003528240.313
establishment of organelle localizationGO:0051656590.313
dna integrity checkpointGO:0031570710.313
purine ribonucleoside triphosphate catabolic processGO:00092073910.312
posttranscriptional regulation of gene expressionGO:00106082130.306
purine nucleotide catabolic processGO:00061954050.299
viral life cycleGO:00190581320.294
purine ribonucleoside metabolic processGO:00461284370.293
positive regulation of intracellular protein transportGO:0090316760.290
regulation of dna recombinationGO:0000018230.290
regulation of nucleocytoplasmic transportGO:0046822980.281
mrna metabolic processGO:00160711750.279
stem cell differentiationGO:0048863930.272
Mouse
dna double strand break processingGO:0000729100.261
positive regulation of hydrolase activityGO:00513453310.260
lymphocyte mediated immunityGO:0002449480.258
actin filament based processGO:00300292240.257
protein localization to organelleGO:00333652800.250
mitotic cell cycle checkpointGO:0007093680.243
meiotic nuclear divisionGO:0007126100.239
organelle fissionGO:00482851490.235
negative regulation of programmed cell deathGO:00430693210.231
Zebrafish
purine nucleoside monophosphate metabolic processGO:00091261860.225
hemopoiesisGO:00300971800.212
Mouse
mrna processingGO:00063971330.209
histone methylationGO:0016571600.209
somatic diversification of immune receptorsGO:000220080.208
regulation of establishment of protein localizationGO:00702012420.208
regulation of gene expression epigeneticGO:0040029730.205
single organism cellular localizationGO:19025803320.197
gene silencingGO:0016458490.193
purine ribonucleotide catabolic processGO:00091544040.191
mismatch repairGO:0006298150.189
purine ribonucleotide biosynthetic processGO:0009152790.188
regulation of viral genome replicationGO:0045069480.186
histone modificationGO:00165702510.181
protein dna complex subunit organizationGO:0071824800.178
interspecies interaction between organismsGO:00444191560.174
positive regulation of helicase activityGO:005109660.170
somatic recombination of immunoglobulin genes involved in immune responseGO:000220430.167
ribonucleotide catabolic processGO:00092614050.157
ras protein signal transductionGO:0007265730.157
telomere maintenance via telomeraseGO:000700480.152
cellular macromolecular complex assemblyGO:00346223240.148
regulation of dna repairGO:0006282470.145
somatic recombination of immunoglobulin gene segmentsGO:001644740.145
regulation of chromatin organizationGO:1902275560.138
leukocyte mediated immunityGO:0002443590.137
regulation of symbiosis encompassing mutualism through parasitismGO:00439031090.136
rna splicingGO:00083801310.133
somatic hypermutation of immunoglobulin genesGO:001644610.132
regulation of growth rateGO:004000910.132
chromatin silencingGO:0006342120.132
protein importGO:00170381300.132
agingGO:0007568660.126
positive regulation of cellular component organizationGO:00511303760.126
cell agingGO:0007569520.126
multi organism cellular processGO:00447641560.123
protein modification by small protein conjugationGO:00324463420.123
macromolecule methylationGO:0043414970.122
positive regulation of dna metabolic processGO:0051054730.122
reciprocal dna recombinationGO:003582540.122
hematopoietic or lymphoid organ developmentGO:00485341860.116
Mouse
telomere maintenanceGO:0000723320.114
positive regulation of developmental processGO:00510943140.113
Mouse
cell morphogenesisGO:00009022960.112
regulation of response to dna damage stimulusGO:2001020940.112
rna polymerase ii transcriptional preinitiation complex assemblyGO:005112340.108
intracellular protein transportGO:00068862700.108
regulation of nucleoside metabolic processGO:00091182090.107
nuclear importGO:00511701060.105
adult locomotory behaviorGO:000834410.104
nuclear transportGO:00511691790.104
response to oxygen containing compoundGO:19017003690.103
cell activation involved in immune responseGO:0002263300.103
microtubule cytoskeleton organizationGO:00002261760.103
chordate embryonic developmentGO:0043009340.102
regulation of purine nucleotide catabolic processGO:00331212050.101
regulation of cytoplasmic transportGO:19036491490.100
response to abiotic stimulusGO:00096283360.100
Zebrafish
positive regulation of nucleocytoplasmic transportGO:0046824540.099
dna unwinding involved in dna replicationGO:000626820.098
modification dependent protein catabolic processGO:00199412090.095
protein adp ribosylationGO:000647190.093
positive regulation of transcription initiation from rna polymerase ii promoterGO:006026140.093
endocytosisGO:00068971590.093
negative regulation of cell cycleGO:00457861930.093
positive regulation of heterochromatin assemblyGO:003145310.092
membrane organizationGO:00610242920.092
positive regulation of apoptotic processGO:00430652460.092
detection of stimulusGO:0051606850.091
interstrand cross link repairGO:003629730.086
dna damage checkpointGO:0000077680.084
rna splicing via transesterification reactionsGO:0000375900.084
mitotic cell cycle phase transitionGO:00447721620.084
protein dna complex assemblyGO:0065004640.083
b cell activationGO:0042113330.080
embryo development ending in birth or egg hatchingGO:0009792340.078
regulation of cell cycleGO:00517263930.077
viral genome replicationGO:0019079500.077
positive regulation of protein complex assemblyGO:0031334860.075
histone lysine methylationGO:0034968500.073
lymphocyte activationGO:00466491330.071
protein catabolic processGO:00301633250.071
protein localization to chromosomeGO:0034502300.070
lymphocyte differentiationGO:0030098350.070
mitochondrion organizationGO:00070051560.070
negative regulation of cell cycle processGO:00109481210.069
atp catabolic processGO:00062001570.069
response to light stimulusGO:0009416870.068
positive regulation of programmed cell deathGO:00430682490.067
maintenance of dna repeat elementsGO:004357040.066
blastocyst developmentGO:000182430.066
dna replication independent nucleosome assemblyGO:0006336270.065
rna interferenceGO:001624640.063
cellular response to transforming growth factor beta stimulusGO:0071560940.062
regulation of double strand break repairGO:2000779220.062
negative regulation of apoptotic processGO:00430663160.061
Zebrafish
cellular response to hormone stimulusGO:00328701250.060
regulation of small gtpase mediated signal transductionGO:00510561560.059
negative regulation of cellular protein metabolic processGO:00322693530.058
mitotic cell cycle processGO:19030472860.057
mitotic dna damage checkpointGO:0044773280.057
regulation of growthGO:00400081650.056
nucleotide excision repairGO:0006289310.055
response to gamma radiationGO:0010332140.055
molting cycleGO:0042303280.054
mitotic cell cycleGO:00002783260.053
cell activationGO:00017752130.053
positive regulation of chromatin assembly or disassemblyGO:004579920.052
meiotic cell cycle processGO:190304680.052
meiotic cell cycleGO:0051321130.051
proteolysis involved in cellular protein catabolic processGO:00516032440.051
regulation of intracellular protein transportGO:00331571230.050
protein targeting to nucleusGO:00447441040.049
response to hormoneGO:00097251750.048
intracellular mrna localizationGO:000829810.048
regulation of nucleotide metabolic processGO:00061402690.048
metaphase plate congressionGO:0051310180.048
positive regulation of intracellular transportGO:00323881040.047
regulation of chromosome organizationGO:00330441030.047
dna replication independent nucleosome organizationGO:0034724270.046
positive regulation of transcription elongation from rna polymerase ii promoterGO:0032968100.045
negative regulation of chromosome organizationGO:2001251480.045
spindle organizationGO:0007051530.044
regulation of ras protein signal transductionGO:00465781550.044
ribonucleoprotein complex biogenesisGO:00226131160.043
positive regulation of cellular component biogenesisGO:00440891580.043
leukocyte activation involved in immune responseGO:0002366300.042
response to cytokineGO:00340972320.042
regulation of cell cycle phase transitionGO:19019871260.041
meiotic chromosome segregationGO:004513240.041
production of molecular mediator of immune responseGO:0002440370.041
cytoplasmic transportGO:00164823790.041
response to oxidative stressGO:00069791210.040
generation of neuronsGO:00486991520.040
Mouse
negative regulation of cell differentiationGO:00455961710.039
ribonucleoside triphosphate catabolic processGO:00092033910.039
symbiosis encompassing mutualism through parasitismGO:00444031560.037
organelle localizationGO:0051640840.036
positive regulation of cell deathGO:00109422630.036
cellular response to insulin stimulusGO:0032869410.036
immune responseGO:00069553070.035
mitotic recombinationGO:000631280.035
locomotory behaviorGO:000762610.034
regulation of protein localizationGO:00328802960.034
regulation of cellular response to stressGO:00801352440.033
protein targetingGO:00066051870.033
methylationGO:00322591060.033
establishment or maintenance of cytoskeleton polarityGO:003095230.033
rna stabilizationGO:0043489180.033
regulation of mitotic cell cycleGO:00073461890.032
establishment of chromosome localizationGO:0051303200.032
recombinational repairGO:0000725500.032
vesicle mediated transportGO:00161923710.032
regulation of protein targetingGO:1903533910.032
leukocyte activationGO:00453211640.032
cellular amine metabolic processGO:0044106410.031
carbohydrate derivative biosynthetic processGO:19011372070.031
positive regulation of protein transportGO:00512221350.031
protein ubiquitinationGO:00165673140.031
cell growthGO:00160491600.031
ribonucleoprotein complex assemblyGO:0022618780.031
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domainsGO:0002460400.030
cardiovascular system developmentGO:00723582620.030
oxidation reduction processGO:00551143960.030
regulation of meiotic cell cycleGO:005144540.030
mitotic chromosome condensationGO:0007076110.029
telomere organizationGO:0032200330.029
receptor mediated endocytosisGO:0006898840.029
cell cycle checkpointGO:00000751170.029
regulation of rna polymerase ii transcriptional preinitiation complex assemblyGO:004589830.028
positive regulation of viral processGO:0048524370.028
microtubule based processGO:00070172100.028
cellular component morphogenesisGO:00329893140.027
response to uvGO:0009411730.027
hematopoietic progenitor cell differentiationGO:0002244380.027
Mouse
positive regulation of transportGO:00510503360.027
positive regulation of purine nucleotide metabolic processGO:19005442270.027
regulation of dna bindingGO:0051101370.027
regenerationGO:003109940.027
regionalizationGO:0003002290.026
establishment of protein localization to organelleGO:00725941720.026
regulation of helicase activityGO:005109580.026
rna splicing via transesterification reactions with bulged adenosine as nucleophileGO:0000377890.026
regulation of cell growthGO:00015581350.025
regulation of multi organism processGO:00439001570.025
regulation of transcription by chromatin organizationGO:003440110.025
modification dependent macromolecule catabolic processGO:00436322120.025
positive regulation of cellular catabolic processGO:00313312840.025
somatic cell dna recombinationGO:001644460.025
anatomical structure homeostasisGO:00602491000.025
regulation of kinase activityGO:00435493140.024
regulation of neuron apoptotic processGO:0043523350.024
protein methylationGO:0006479740.024
regulation of protein localization to nucleusGO:1900180850.024
cellular response to organonitrogen compoundGO:00714171240.023
generation of precursor metabolites and energyGO:0006091680.023
chromosome condensationGO:0030261150.023
response to woundingGO:00096111680.022
enzyme linked receptor protein signaling pathwayGO:00071673030.022
regulation of atp metabolic processGO:1903578290.022
ribonucleoprotein complex subunit organizationGO:0071826810.022
nervous system developmentGO:00073992930.022
Mouse
cell cycle phase transitionGO:00447701730.022
leukocyte differentiationGO:0002521980.022
ubiquitin dependent protein catabolic processGO:00065112060.022
protein alkylationGO:0008213740.022
negative regulation of gene silencing by rnaGO:006096730.021
response to external biotic stimulusGO:00432072610.021
reproductive system developmentGO:0061458560.021
single organism nuclear importGO:19025931040.021
extrinsic apoptotic signaling pathwayGO:00971911190.021
negative regulation of protein maturationGO:19033181420.021
gene silencing by rnaGO:0031047260.021
positive regulation of bindingGO:0051099450.021
lymphocyte activation involved in immune responseGO:0002285200.021
rna catabolic processGO:0006401710.020
regulation of chromatin assembly or disassemblyGO:000167260.020
organelle assemblyGO:00709251760.020
regulation of immune responseGO:00507762010.020
somatic diversification of immunoglobulinsGO:001644560.020
immunoglobulin mediated immune responseGO:0016064100.020
regulation of nucleotide catabolic processGO:00308112050.019
protein processingGO:00164852260.019
female gamete generationGO:000729220.019
dna catabolic process endonucleolyticGO:0000737370.019
dna templated transcription initiationGO:0006352350.019
posttranscriptional gene silencing by rnaGO:0035194250.019
cell developmentGO:00484683280.018
Mouse
single organism carbohydrate metabolic processGO:00447231930.018
positive regulation of nfat protein import into nucleusGO:005153330.018
response to hypoxiaGO:0001666960.018
mitotic nuclear divisionGO:00070671190.017
protein localization to nucleusGO:00345041360.017
regulation of dna methylationGO:004403020.017
nucleocytoplasmic transportGO:00069131760.017
dna catabolic process exonucleolyticGO:0000738170.017
positive regulation of transferase activityGO:00513472270.017
regulation of purine nucleotide metabolic processGO:19005422640.017
mitotic spindle organizationGO:0007052270.017
regulation of protein processingGO:00706131500.017
single organism reproductive processGO:0044702980.017
immune effector processGO:00022521590.017
rna phosphodiester bond hydrolysisGO:0090501350.016
regulation of chromatin modificationGO:1903308510.016
macromolecule glycosylationGO:0043413630.016
transmembrane receptor protein serine threonine kinase signaling pathwayGO:00071781250.016
somatic diversification of immune receptors via somatic mutationGO:000256610.016
carbohydrate metabolic processGO:00059752070.016
regulation of cellular component biogenesisGO:00440872810.015
development of primary sexual characteristicsGO:0045137350.015
circulatory system developmentGO:00723592620.015
protein poly adp ribosylationGO:007021230.015
b cell activation involved in immune responseGO:000231250.015
double strand break repair via single strand annealingGO:004500240.015
ribose phosphate biosynthetic processGO:0046390820.015
regulation of bindingGO:00510981110.015
smad protein import into nucleusGO:0007184130.015
positive regulation of nucleotide catabolic processGO:00308131850.015
regulation of gene silencingGO:0060968240.014
response to peptide hormoneGO:0043434610.014
positive regulation of viral genome replicationGO:0045070150.014
rna dependent dna replicationGO:0006278160.014
response to heatGO:0009408210.014
ribosome assemblyGO:004225590.014
negative regulation of proteolysisGO:00458611320.014
regulation of protein complex assemblyGO:00432541470.014
positive regulation of catabolic processGO:00098963100.014
response to organic cyclic compoundGO:00140702040.014
regulation of protein transportGO:00512232130.014
cellular ketone metabolic processGO:0042180800.014
regulation of cell substrate adhesionGO:0010810680.014
cellular response to growth factor stimulusGO:00713631970.013
positive regulation of organelle organizationGO:00106381950.013
single organism membrane organizationGO:00448022680.013
multicellular organismal reproductive processGO:0048609400.013
reproductionGO:0000003630.013
negative regulation of neuron deathGO:1901215320.013
protein maturationGO:00516042330.013
glycoprotein biosynthetic processGO:0009101910.013
rna processingGO:00063962550.013
regulation of histone modificationGO:0031056470.013
response to nutrient levelsGO:0031667810.013
positive regulation of multi organism processGO:0043902560.013
sulfate transportGO:000827250.013
cellular component disassembly involved in execution phase of apoptosisGO:0006921130.013
spermatid developmentGO:000728640.012
positive regulation of cell proliferationGO:00082843010.012
reproductive structure developmentGO:0048608550.012
mitotic centrosome separationGO:000710010.012
negative regulation of mitotic cell cycleGO:00459301020.012
positive regulation of gtpase activityGO:00435471660.012
protein import into nucleusGO:00066061040.012
nucleotide biosynthetic processGO:00091651090.012
neuron apoptotic processGO:0051402390.012
postreplication repairGO:0006301120.012
double strand break repair via homologous recombinationGO:0000724500.012
mitotic g2 dna damage checkpointGO:000709570.012
immunoglobulin v d j recombinationGO:003315210.011
cell projection organizationGO:00300302520.011
translationGO:00064121320.011
neuron differentiationGO:00301821380.011
spindle assemblyGO:0051225290.011
regulation of cell adhesionGO:00301551660.011
cellular response to oxidative stressGO:0034599850.011
guanosine containing compound metabolic processGO:19010682440.011
muscle contractionGO:0006936730.011
oocyte developmentGO:004859910.011
male gamete generationGO:0048232220.010
nucleoside biosynthetic processGO:0009163260.010
neurogenesisGO:00220081690.010
Mouse
growthGO:00400072020.010
Worm
system processGO:00030083490.010
cellular response to nitrogen compoundGO:19016991440.010
positive regulation of immune system processGO:00026842830.010
ribonucleotide biosynthetic processGO:0009260810.010

XRCC5 disease predictions

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of cellular proliferationDOID:145661740.380
cancerDOID:1621670.068
organ system cancerDOID:00506861640.068