Homo sapiens

49 known processes

TPP1

tripeptidyl peptidase I

(Aliases: LPIC,MGC21297,CLN2)

TPP1 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
detection of chemical stimulusGO:0009593550.888
positive regulation of natural killer cell mediated immunityGO:0002717120.567
neurological system processGO:00508771630.471
Mouse
system processGO:00030083490.435
Mouse
anatomical structure homeostasisGO:00602491000.368
vacuole organizationGO:0007033440.316
Mouse
cellular lipid catabolic processGO:0044242650.238
detection of chemical stimulus involved in sensory perceptionGO:0050907330.222
sensory perception of bitter tasteGO:0050913280.194
vasculature developmentGO:00019441810.175
lipid catabolic processGO:0016042840.174
regulation of leukocyte mediated immunityGO:0002703380.174
signal transduction by phosphorylationGO:00230142970.167
sensory perception of tasteGO:0050909360.159
negative regulation of multicellular organismal processGO:00512413170.157
locomotory behaviorGO:000762610.153
carbohydrate catabolic processGO:0016052360.143
epithelial cell proliferationGO:00506731280.140
regulation of epithelial cell proliferationGO:00506781130.137
multicellular organismal agingGO:001025930.136
proteolysis involved in cellular protein catabolic processGO:00516032440.135
carbohydrate metabolic processGO:00059752070.131
protein catabolic processGO:00301633250.128
lipid metabolic processGO:00066293810.128
regulation of defense responseGO:00313471540.125
regulation of cellular amino acid metabolic processGO:000652160.122
protein localization to organelleGO:00333652800.119
cellular amine metabolic processGO:0044106410.114
prostate gland developmentGO:003085030.111
negative regulation of dendritic cell differentiationGO:200119920.108
response to bacteriumGO:00096171440.100
post embryonic developmentGO:000979120.100
determination of adult lifespanGO:000834020.096
sensory perceptionGO:00076001030.095
response to oxygen containing compoundGO:19017003690.092
apoptotic signaling pathwayGO:00971902680.090
cytokine productionGO:00018162470.088
transmembrane receptor protein tyrosine kinase signaling pathwayGO:00071691810.086
cellular amino acid metabolic processGO:00065201160.085
circulatory system developmentGO:00723592620.082
ganglioside catabolic processGO:000668930.082
tissue regenerationGO:004224630.079
cellular homeostasisGO:00197251960.078
cellular macromolecule catabolic processGO:00442653800.076
antigen processing and presentationGO:0019882330.076
regulation of systemic arterial blood pressure by circulatory renin angiotensinGO:000199140.075
regulation of angiogenesisGO:0045765920.075
multicellular organismal homeostasisGO:0048871670.074
lipid localizationGO:00108761060.072
epithelium developmentGO:00604292270.071
negative regulation of cell proliferationGO:00082852280.071
g protein coupled receptor signaling pathway coupled to cyclic nucleotide second messengerGO:0007187430.071
cellular response to hydrogen peroxideGO:0070301370.069
antigen processing and presentation via mhc class ibGO:000247530.067
protein maturationGO:00516042330.066
positive regulation of immune responseGO:00507781590.066
sensory perception of chemical stimulusGO:0007606380.065
nervous system developmentGO:00073992930.061
immune effector processGO:00022521590.061
regulation of mapk cascadeGO:00434082620.060
negative regulation of cellular protein metabolic processGO:00322693530.060
positive regulation of immune system processGO:00026842830.059
leukocyte mediated immunityGO:0002443590.059
positive regulation of t cell tolerance inductionGO:000266620.059
lymphocyte activationGO:00466491330.059
lymphocyte mediated immunityGO:0002449480.058
cellular amide metabolic processGO:0043603690.057
single organism carbohydrate metabolic processGO:00447231930.056
detection of external biotic stimulusGO:0098581190.056
adaptive immune responseGO:0002250490.055
positive regulation of cytokine productionGO:00018191670.054
metal ion transportGO:00300012720.050
chemical homeostasisGO:00488783060.049
cellular ketone metabolic processGO:0042180800.049
ganglioside metabolic processGO:000157370.049
oogenesisGO:004847720.048
amino sugar metabolic processGO:0006040150.047
glycolipid metabolic processGO:0006664270.047
regulation of cytokine productionGO:00018172320.046
female gamete generationGO:000729220.046
positive regulation of lymphocyte activationGO:0051251730.046
regulation of transferase activityGO:00513383550.046
positive regulation of defense responseGO:0031349870.045
positive regulation of innate immune responseGO:0045089790.044
proteasomal protein catabolic processGO:00104981760.044
positive regulation of cell activationGO:0050867810.043
matingGO:000761810.043
cellular response to endogenous stimulusGO:00714953360.043
innate immune responseGO:00450871780.043
cell developmentGO:00484683280.042
negative regulation of immune system processGO:00026831360.041
negative regulation of glycoprotein metabolic processGO:190301980.040
regulation of lymphocyte activationGO:00512491030.040
negative regulation of fibroblast growth factor receptor signaling pathwayGO:004003720.039
regulation of natural killer cell mediated immunityGO:0002715160.038
modification dependent protein catabolic processGO:00199412090.038
protection from natural killer cell mediated cytotoxicityGO:004227030.038
reproductive processGO:00224141060.038
immune responseGO:00069553070.038
regulation of cellular ketone metabolic processGO:0010565500.037
long term memoryGO:000761620.037
anatomical structure formation involved in morphogenesisGO:00486462840.037
cellular protein catabolic processGO:00442572610.037
wnt signaling pathwayGO:00160551560.037
regulation of lymphocyte proliferationGO:0050670640.036
cellular response to thyroid hormone stimulusGO:009706790.036
membrane lipid metabolic processGO:0006643530.036
positive regulation of cellular amine metabolic processGO:003324070.036
response to thyroid hormoneGO:009706690.035
intracellular protein transportGO:00068862700.035
regulation of lipid metabolic processGO:0019216960.035
defense responseGO:00069523150.035
immune response regulating signaling pathwayGO:0002764970.035
detection of biotic stimulusGO:0009595210.035
proteasome mediated ubiquitin dependent protein catabolic processGO:00431611560.034
antigen processing and presentation of peptide antigenGO:0048002180.034
peripheral nervous system developmentGO:000742220.034
detection of chemical stimulus involved in sensory perception of tasteGO:0050912310.034
cell morphogenesisGO:00009022960.034
positive regulation of mapk cascadeGO:00434101900.033
response to oxidative stressGO:00069791210.033
ion homeostasisGO:00508012300.033
cellular ion homeostasisGO:00068731680.033
regulation of immune responseGO:00507762010.032
growthGO:00400072020.032
immune response regulating cell surface receptor signaling pathwayGO:0002768510.032
regulation of blood vessel remodelingGO:006031220.032
negative regulation of cell deathGO:00605483450.031
leukocyte activationGO:00453211640.031
regenerationGO:003109940.031
modification dependent macromolecule catabolic processGO:00436322120.031
positive regulation of lymphocyte differentiationGO:0045621130.031
cell projection organizationGO:00300302520.030
negative regulation of immune responseGO:0050777400.030
positive regulation of interferon gamma productionGO:0032729260.030
enzyme linked receptor protein signaling pathwayGO:00071673030.030
tissue homeostasisGO:0001894630.030
liposaccharide metabolic processGO:1903509270.029
detection of stimulusGO:0051606850.029
negative regulation of elastin catabolic processGO:006031110.029
immune response inhibiting cell surface receptor signaling pathwayGO:000276740.028
positive regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domainsGO:0002824190.028
positive regulation of interleukin 12 productionGO:003273580.028
regulation of cellular amine metabolic processGO:0033238110.027
response to organonitrogen compoundGO:00102431560.027
regulation of regulatory t cell differentiationGO:004558940.027
cell adhesionGO:00071553250.027
amine metabolic processGO:0009308440.027
regulation of vasculature developmentGO:1901342970.027
regulation of cell activationGO:00508651250.027
cellular response to reactive oxygen speciesGO:0034614500.026
regulation of tolerance inductionGO:000264340.026
transition metal ion transportGO:0000041230.026
positive regulation of regulatory t cell differentiationGO:004559130.025
detection of stimulus involved in sensory perceptionGO:0050906430.025
regulation of cellular response to stressGO:00801352440.025
regulation of wnt signaling pathwayGO:00301111230.025
retina homeostasisGO:0001895420.025
regulation of protein maturationGO:19033171500.025
cation transportGO:00068123310.025
gland developmentGO:0048732480.025
blastocyst developmentGO:000182430.024
regulation of leukocyte differentiationGO:1902105610.024
cellular lipid metabolic processGO:00442553030.024
negative regulation of vasculature developmentGO:1901343430.024
positive regulation of leukocyte mediated immunityGO:0002705240.024
positive regulation of immune effector processGO:0002699400.024
regulation of elastin catabolic processGO:006031010.024
ubiquitin dependent protein catabolic processGO:00065112060.023
regulation of t cell activationGO:0050863770.023
neuromuscular processGO:0050905150.023
Mouse
maintenance of locationGO:00512351120.023
regulation of secretionGO:00510461940.023
intracellular receptor signaling pathwayGO:00305221040.023
vesicle mediated transportGO:00161923710.023
regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domainsGO:0002822290.023
regulation of intracellular transportGO:00323861950.022
sulfur compound metabolic processGO:00067901010.022
neuronal action potentialGO:001922890.022
cytoplasmic transportGO:00164823790.022
cell activationGO:00017752130.022
response to other organismGO:00517072610.022
response to hormoneGO:00097251750.022
blood vessel morphogenesisGO:00485141620.021
regulation of protein transportGO:00512232130.021
memoryGO:000761330.021
regulation of leukocyte activationGO:00026941150.021
inorganic ion transmembrane transportGO:00986602310.021
regulation of angiotensin levels in bloodGO:000200230.021
regulation of kinase activityGO:00435493140.021
single organism reproductive processGO:0044702980.021
positive regulation of aldosterone biosynthetic processGO:003234920.021
positive regulation of cell proliferationGO:00082843010.021
urogenital system developmentGO:0001655650.020
regulation of natural killer cell mediated cytotoxicityGO:0042269160.020
negative regulation of collagen catabolic processGO:001071110.020
endosomal transportGO:00161971290.020
hemopoiesisGO:00300971800.020
single organism membrane organizationGO:00448022680.020
negative regulation of developmental processGO:00510932470.020
t cell differentiationGO:0030217290.020
regulation of peptidyl tyrosine phosphorylationGO:00507301080.020
cellular response to oxygen containing compoundGO:19017012760.020
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domainsGO:0002460400.020
positive regulation of cellular amino acid metabolic processGO:004576430.019
regulation of establishment of protein localizationGO:00702012420.019
t cell tolerance inductionGO:000251740.019
secretionGO:00469032540.019
negative regulation of phosphorus metabolic processGO:00105632670.018
neurogenesisGO:00220081690.018
monovalent inorganic cation transportGO:00156721280.018
negative regulation of cellular response to oxidative stressGO:1900408180.018
negative regulation of metalloenzyme activityGO:004855310.018
negative regulation of intracellular signal transductionGO:19025321830.018
response to woundingGO:00096111680.018
positive regulation of t cell activationGO:0050870540.018
regulation of protein localizationGO:00328802960.018
positive regulation of tolerance inductionGO:000264520.018
negative regulation of catalytic activityGO:00430863350.017
regulation of protein kinase activityGO:00458592890.017
embryo developmentGO:00097901230.017
response to nitrogen compoundGO:19016981840.017
dna replicationGO:00062601160.017
negative regulation of phosphate metabolic processGO:00459362670.017
angiogenesisGO:00015251470.017
regulation of endothelial cell proliferationGO:0001936560.017
establishment of protein localization to organelleGO:00725941720.017
oocyte differentiationGO:000999420.017
positive regulation of leukocyte differentiationGO:1902107370.017
endothelial cell proliferationGO:0001935650.017
positive regulation of developmental processGO:00510943140.017
regulation of collagen catabolic processGO:001071030.017
response to axon injuryGO:004867810.017
cellular response to oxidative stressGO:0034599850.017
immune response inhibiting signal transductionGO:000276540.017
regulation of protein catabolic processGO:00421761550.016
peptidyl tyrosine phosphorylationGO:00181081700.016
regulation of cell killingGO:0031341220.016
blastoderm segmentationGO:000735020.016
generation of neuronsGO:00486991520.016
regulation of lymphocyte mediated immunityGO:0002706330.016
transmembrane transportGO:00550853990.016
somatic muscle developmentGO:000752510.016
positive regulation of phosphorylationGO:00423273940.016
regulation of cellular response to growth factor stimulusGO:0090287760.016
regulation of innate immune responseGO:0045088970.016
response to reactive oxygen speciesGO:0000302610.016
t cell activationGO:0042110990.016
negative regulation of programmed cell deathGO:00430693210.015
neuromuscular process controlling postureGO:005088420.015
response to biotic stimulusGO:00096072760.015
behaviorGO:00076101120.015
regulation of immune effector processGO:0002697910.015
regulation of anatomical structure morphogenesisGO:00226032860.015
negative regulation of epithelial cell proliferationGO:0050680480.015
positive regulation of epithelial cell proliferationGO:0050679650.015
hematopoietic or lymphoid organ developmentGO:00485341860.015
positive regulation of secretionGO:00510471160.015
blood vessel developmentGO:00015681720.015
negative regulation of cellular amine metabolic processGO:003323930.015
regulation of oxidative stress induced cell deathGO:1903201240.015
negative regulation of protein modification processGO:00314002000.015
neuron differentiationGO:00301821380.015
head developmentGO:00603221080.015
mapk cascadeGO:00001652880.015
positive regulation of aldosterone metabolic processGO:003234620.015
multicellular organismal metabolic processGO:0044236340.014
positive regulation of leukocyte activationGO:0002696800.014
lipid transportGO:0006869900.014
negative regulation of cellular catabolic processGO:0031330830.014
regulation of t cell tolerance inductionGO:000266440.014
action potentialGO:0001508340.014
circulatory system processGO:00030131130.014
respiratory system processGO:000301630.014
regulation of anatomical structure sizeGO:00900661010.014
oxidation reduction processGO:00551143960.014
negative regulation of protein metabolic processGO:00512483910.014
negative regulation of oxidative stress induced cell deathGO:1903202170.014
regulation of t cell differentiationGO:0045580190.014
segmentationGO:003528240.014
neuron projection developmentGO:00311751060.014
regulation of cytokine secretionGO:0050707570.014
monovalent inorganic cation homeostasisGO:0055067370.013
natural killer cell mediated cytotoxicityGO:0042267230.013
t cell proliferationGO:0042098450.013
protein modification by small protein conjugationGO:00324463420.013
protein processingGO:00164852260.013
interferon gamma productionGO:0032609390.013
response to organic cyclic compoundGO:00140702040.013
divalent inorganic cation homeostasisGO:00725071360.013
positive regulation of leukocyte degranulationGO:004330230.013
muscle cell cellular homeostasisGO:004671630.013
positive regulation of steroid hormone biosynthetic processGO:009003120.013
kidney developmentGO:0001822530.013
response to external biotic stimulusGO:00432072610.013
positive regulation of transmembrane receptor protein serine threonine kinase signaling pathwayGO:0090100410.012
defense response to bacteriumGO:0042742630.012
cellular response to hormone stimulusGO:00328701250.012
regulation of adaptive immune responseGO:0002819330.012
cell killingGO:0001906340.012
dephosphorylationGO:00163112090.012
neuron developmentGO:00486661130.012
transmembrane receptor protein serine threonine kinase signaling pathwayGO:00071781250.012
regulation of systemic arterial blood pressure by hormoneGO:0001990120.012
cell death in response to hydrogen peroxideGO:0036474100.012
single organism carbohydrate catabolic processGO:0044724330.012
protein oligomerizationGO:00512591730.012
positive regulation of cell cycleGO:00457871400.012
positive regulation of lymphocyte mediated immunityGO:0002708230.012
negative regulation of transferase activityGO:00513481240.012
cellular response to extracellular stimulusGO:0031668720.012
positive regulation of transportGO:00510503360.012
vacuolar transportGO:0007034340.012
lytic vacuole organizationGO:0080171240.012
Mouse
response to hydrogen peroxideGO:0042542400.011
cellular carbohydrate metabolic processGO:0044262840.011
nucleocytoplasmic transportGO:00069131760.011
negative regulation of cell motilityGO:20001461040.011
central nervous system developmentGO:00074171230.011
positive regulation of protein kinase activityGO:00458601900.011
multicellular organismal signalingGO:0035637340.011
negative regulation of blood vessel morphogenesisGO:2000181410.011
heparan sulfate proteoglycan metabolic processGO:0030201120.011
cellular component morphogenesisGO:00329893140.011
negative regulation of protein catabolic processGO:0042177590.011
negative regulation of cellular amino acid metabolic processGO:004576320.011
regulation of interferon gamma productionGO:0032649360.011
regulation of membrane potentialGO:0042391950.011
immune system developmentGO:00025201950.011
anion transportGO:00068201610.011
regulation of hydrogen peroxide induced cell deathGO:1903205100.011
diaphragm contractionGO:000208610.011
positive regulation of dna metabolic processGO:0051054730.011
transmission of nerve impulseGO:0019226110.011
negative regulation of catabolic processGO:00098951040.011
secretion by cellGO:00329402260.011
positive regulation of kinase activityGO:00336742040.011
response to abiotic stimulusGO:00096283360.011
positive regulation of t cell differentiationGO:0045582110.011
negative regulation of hydrolase activityGO:00513461820.011
nuclear transportGO:00511691790.011
response to peptide hormoneGO:0043434610.011
ossificationGO:00015031210.011
sensory perception of soundGO:0007605370.011
cardiovascular system developmentGO:00723582620.011
sensory perception of mechanical stimulusGO:0050954370.011
cellular protein complex assemblyGO:00436231880.011
divalent inorganic cation transportGO:00725111580.011
positive regulation of intracellular transportGO:00323881040.010
regulation of transmembrane receptor protein serine threonine kinase signaling pathwayGO:0090092900.010
adenylate cyclase inhibiting g protein coupled receptor signaling pathwayGO:0007193220.010
purine containing compound catabolic processGO:00725234110.010
leukocyte differentiationGO:0002521980.010
negative regulation of cell migrationGO:00303361020.010
negative regulation of cell differentiationGO:00455961710.010
establishment of planar polarityGO:000173630.010
regulation of interleukin 12 productionGO:0032655150.010
sensory perception of painGO:001923340.010
cell projection morphogenesisGO:00488581290.010
detection of chemical stimulus involved in sensory perception of bitter tasteGO:0001580280.010

TPP1 disease predictions

DiseaseDO term IDSizeProbabilityFunc Analog Org
inherited metabolic disorderDOID:6552421.000
disease of metabolismDOID:00146672951.000
lysosomal storage diseaseDOID:3211471.000
lipid storage diseaseDOID:9455280.968
nervous system diseaseDOID:8634310.730
central nervous system diseaseDOID:3311860.730
neuronal ceroid lipofuscinosisDOID:14503110.552
brain diseaseDOID:936730.247
sphingolipidosisDOID:1927140.137
cerebral degenerationDOID:1443160.059
leukodystrophyDOID:1057980.059
epilepsy syndromeDOID:1826410.032
progressive myoclonus epilepsyDOID:89180.032
electroclinical syndromeDOID:0050701320.032
variable age at onset electroclinical syndromeDOID:005070680.032
immune system diseaseDOID:29141550.016
sensory system diseaseDOID:00501552030.016
neurodegenerative diseaseDOID:12891020.011