Homo sapiens

0 known processes

PTPLB

protein tyrosine phosphatase-like (proline instead of catalytic arginine), member b

(Aliases: HACD2)

PTPLB biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
mitochondrial calcium ion homeostasisGO:0051560110.818
positive regulation of mitochondrial calcium ion concentrationGO:005156180.603
long chain fatty acid catabolic processGO:004275830.222
calcium ion homeostasisGO:00550741220.154
divalent inorganic cation homeostasisGO:00725071360.151
cellular divalent inorganic cation homeostasisGO:00725031280.145
negative regulation of endoplasmic reticulum calcium ion concentrationGO:003247160.130
ion homeostasisGO:00508012300.122
cellular calcium ion homeostasisGO:00068741170.121
chemical homeostasisGO:00488783060.118
ion transmembrane transportGO:00342203380.115
membrane organizationGO:00610242920.103
cation homeostasisGO:00550801890.103
cellular metal ion homeostasisGO:00068751460.102
cytoplasmic transportGO:00164823790.100
lipid metabolic processGO:00066293810.092
metal ion homeostasisGO:00550651690.088
cellular lipid metabolic processGO:00442553030.085
protein localization to membraneGO:00726571600.084
anion transportGO:00068201610.083
cellular ketone metabolic processGO:0042180800.073
single organism membrane organizationGO:00448022680.068
cellular component morphogenesisGO:00329893140.066
cellular ion homeostasisGO:00068731680.065
calcium mediated signaling using intracellular calcium sourceGO:003558470.064
cellular chemical homeostasisGO:00550821800.064
transmembrane transportGO:00550853990.063
vesicle mediated transportGO:00161923710.062
positive regulation of transportGO:00510503360.061
long chain fatty acid metabolic processGO:0001676300.061
protein o linked glycosylation via threonineGO:001824340.058
cell developmentGO:00484683280.058
cellular cation homeostasisGO:00300031630.054
lipid biosynthetic processGO:00086101770.054
post embryonic developmentGO:000979120.052
Worm
morphogenesis of embryonic epitheliumGO:001633140.051
cellular homeostasisGO:00197251960.050
multicellular organismal agingGO:001025930.049
embryonic epithelial tube formationGO:000183840.048
organonitrogen compound biosynthetic processGO:19015662000.047
positive regulation of cytosolic calcium ion concentrationGO:0007204820.045
lipid modificationGO:0030258840.045
cellular amine metabolic processGO:0044106410.045
amine metabolic processGO:0009308440.045
organic hydroxy compound metabolic processGO:19016151470.044
oogenesisGO:004847720.044
regulation of cellular amino acid metabolic processGO:000652160.044
regulation of cellular ketone metabolic processGO:0010565500.044
cytosolic calcium ion homeostasisGO:0051480890.043
organic anion transportGO:00157111030.043
small molecule biosynthetic processGO:00442831570.042
peroxisome organizationGO:0007031280.041
female gamete generationGO:000729220.039
cellular amino acid metabolic processGO:00065201160.038
locomotory behaviorGO:000762610.036
positive regulation of cellular component organizationGO:00511303760.036
endomembrane system organizationGO:00102561960.035
oxidation reduction processGO:00551143960.035
neuromuscular junction developmentGO:000752830.034
regulation of proteolysisGO:00301622930.034
segmentationGO:003528240.034
immune responseGO:00069553070.034
protein o linked glycosylation via serineGO:001824230.033
cell projection organizationGO:00300302520.032
osteoblast differentiationGO:0001649920.032
phospholipid metabolic processGO:0006644990.031
golgi vesicle transportGO:0048193800.031
oocyte developmentGO:004859910.031
cell adhesionGO:00071553250.031
positive regulation of cellular amino acid metabolic processGO:004576430.031
cation transmembrane transportGO:00986552380.031
anion transmembrane transportGO:0098656760.031
protein localization to plasma membraneGO:0072659930.031
inorganic ion transmembrane transportGO:00986602310.031
negative regulation of cellular amine metabolic processGO:003323930.030
regulation of endopeptidase activityGO:00525481700.030
regulation of cellular component movementGO:00512703340.030
cation transportGO:00068123310.030
inorganic cation transmembrane transportGO:00986621940.030
oocyte differentiationGO:000999420.029
carbohydrate derivative biosynthetic processGO:19011372070.029
glycerolipid metabolic processGO:00464861070.029
signal transduction by phosphorylationGO:00230142970.029
positive regulation of developmental processGO:00510943140.028
plasma membrane organizationGO:00070091150.028
alcohol metabolic processGO:00060661140.028
ossificationGO:00015031210.028
carboxylic acid transportGO:0046942630.027
spermatid differentiationGO:004851540.027
determination of adult lifespanGO:000834020.027
nervous system developmentGO:00073992930.027
mitotic cell cycle processGO:19030472860.026
neural tube formationGO:000184130.026
positive regulation of cellular amine metabolic processGO:003324070.025
nucleoside monophosphate catabolic processGO:00091251590.025
monovalent inorganic cation transportGO:00156721280.025
positive regulation of programmed cell deathGO:00430682490.025
membrane lipid metabolic processGO:0006643530.025
negative regulation of cellular amino acid metabolic processGO:004576320.025
positive regulation of cell deathGO:00109422630.025
organophosphate biosynthetic processGO:00904071630.025
positive regulation of hydrolase activityGO:00513453310.025
carbohydrate metabolic processGO:00059752070.024
intrinsic apoptotic signaling pathwayGO:00971931270.024
regulation of cellular amine metabolic processGO:0033238110.024
negative regulation of catalytic activityGO:00430863350.024
biological adhesionGO:00226103310.023
secretion by cellGO:00329402260.023
Worm
response to organic cyclic compoundGO:00140702040.023
cellular macromolecule catabolic processGO:00442653800.023
nucleoside monophosphate metabolic processGO:00091231910.023
spermatid developmentGO:000728640.023
metal ion transportGO:00300012720.023
regulation of cell migrationGO:00303342890.023
regulation of cell cycleGO:00517263930.022
monocarboxylic acid metabolic processGO:00327871850.022
protein catabolic processGO:00301633250.022
purine ribonucleoside metabolic processGO:00461284370.022
positive regulation of cell proliferationGO:00082843010.022
single organism carbohydrate metabolic processGO:00447231930.022
regulation of protein localizationGO:00328802960.022
positive regulation of cellular catabolic processGO:00313312840.022
sulfur compound metabolic processGO:00067901010.022
associative learningGO:000830610.022
negative regulation of apoptotic processGO:00430663160.021
regulation of intracellular transportGO:00323861950.021
anterior posterior axis specification embryoGO:000859520.021
second messenger mediated signalingGO:0019932780.021
apoptotic signaling pathwayGO:00971902680.021
positive regulation of apoptotic processGO:00430652460.021
regulation of anatomical structure morphogenesisGO:00226032860.021
dephosphorylationGO:00163112090.021
intracellular protein transportGO:00068862700.021
lipid localizationGO:00108761060.021
regulation of peptidase activityGO:00525471800.021
purine nucleotide catabolic processGO:00061954050.021
response to salt stressGO:000965130.021
epithelium developmentGO:00604292270.021
ribonucleoside triphosphate metabolic processGO:00091994120.021
single organism membrane fusionGO:0044801370.020
proteolysis involved in cellular protein catabolic processGO:00516032440.020
response to abiotic stimulusGO:00096283360.020
positive regulation of peptidase activityGO:0010952880.020
tripartite regional subdivisionGO:000735120.020
regulation of cell differentiationGO:00455953930.020
autophagyGO:0006914880.020
ubiquitin dependent protein catabolic processGO:00065112060.020
lipid transportGO:0006869900.020
protein maturationGO:00516042330.019
reactive oxygen species biosynthetic processGO:190340940.019
organic acid transportGO:0015849650.019
regulation of lipid metabolic processGO:0019216960.019
cell growthGO:00160491600.019
glycerophospholipid metabolic processGO:0006650840.019
regulation of intrinsic apoptotic signaling pathwayGO:2001242720.019
negative regulation of cellular protein metabolic processGO:00322693530.019
calcium mediated signalingGO:0019722440.019
atp metabolic processGO:00460341760.019
actin filament based processGO:00300292240.019
negative regulation of phosphate metabolic processGO:00459362670.019
apoptotic mitochondrial changesGO:0008637570.019
establishment or maintenance of epithelial cell apical basal polarityGO:004519710.019
negative regulation of phosphorus metabolic processGO:00105632670.019
negative regulation of intracellular signal transductionGO:19025321830.018
neurological system processGO:00508771630.018
proteasome mediated ubiquitin dependent protein catabolic processGO:00431611560.018
regulation of lipid catabolic processGO:0050994230.018
reactive nitrogen species metabolic processGO:200105730.018
purine nucleoside monophosphate metabolic processGO:00091261860.018
nucleotide catabolic processGO:00091664080.018
regulation of cell motilityGO:20001452990.018
single organism cellular localizationGO:19025803320.018
regulation of apoptotic signaling pathwayGO:20012331750.018
ribonucleoside catabolic processGO:00424544060.018
cell part morphogenesisGO:00329901370.018
negative regulation of protein metabolic processGO:00512483910.018
protein localization to endoplasmic reticulumGO:0070972190.018
negative regulation of protein modification processGO:00314002000.018
endocytosisGO:00068971590.018
negative regulation of cellular component organizationGO:00511292350.018
cell morphogenesisGO:00009022960.018
cell cycle phase transitionGO:00447701730.018
mitotic cell cycleGO:00002783260.017
positive regulation of secretionGO:00510471160.017
proteasomal protein catabolic processGO:00104981760.017
maintenance of locationGO:00512351120.017
purine containing compound catabolic processGO:00725234110.017
reactive oxygen species metabolic processGO:0072593750.017
reproductive processGO:00224141060.017
regulation of ion transportGO:00432691890.017
nucleoside triphosphate metabolic processGO:00091414220.017
regulation of cysteine type endopeptidase activityGO:20001161270.017
blastoderm segmentationGO:000735020.016
secretionGO:00469032540.016
Worm
organophosphate catabolic processGO:00464344300.016
regulation of locomotionGO:00400123290.016
positive regulation of apoptotic signaling pathwayGO:2001235700.016
primary neural tube formationGO:001402030.016
positive regulation of proteolysisGO:00458621420.016
anatomical structure formation involved in morphogenesisGO:00486462840.016
positive regulation of endopeptidase activityGO:0010950840.016
organic acid biosynthetic processGO:0016053970.016
ribose phosphate biosynthetic processGO:0046390820.016
ribonucleotide catabolic processGO:00092614050.016
response to biotic stimulusGO:00096072760.016
endosomal transportGO:00161971290.016
establishment of protein localization to membraneGO:00901501210.016
neuron projection developmentGO:00311751060.016
purine ribonucleoside monophosphate catabolic processGO:00091691580.016
organophosphate ester transportGO:0015748320.016
system processGO:00030083490.016
rhythmic behaviorGO:000762220.016
cellular response to dna damage stimulusGO:00069743790.015
purine nucleoside triphosphate metabolic processGO:00091444120.015
anterior posterior axis specificationGO:000994820.015
cellular protein catabolic processGO:00442572610.015
membrane lipid biosynthetic processGO:0046467270.015
establishment or maintenance of bipolar cell polarityGO:006124520.015
long chain fatty acid transportGO:0015909180.015
regulation of cell developmentGO:00602841610.015
positive regulation of catabolic processGO:00098963100.015
modification dependent protein catabolic processGO:00199412090.015
neuron differentiationGO:00301821380.015
lipoprotein biosynthetic processGO:0042158330.015
establishment of protein localization to organelleGO:00725941720.015
positive regulation of intracellular transportGO:00323881040.015
regulation of reactive oxygen species biosynthetic processGO:190342630.015
nitrogen compound transportGO:00717051910.015
cellular response to oxygen containing compoundGO:19017012760.015
regulation of protein processingGO:00706131500.015
positive regulation of reactive oxygen species biosynthetic processGO:190342820.015
regulation of cell cycle processGO:00105642660.015
potassium ion transportGO:0006813620.015
microtubule based processGO:00070172100.015
regulation of protein transportGO:00512232130.014
regulation of growthGO:00400081650.014
protein targetingGO:00066051870.014
nucleoside triphosphate catabolic processGO:00091433940.014
regulation of mapk cascadeGO:00434082620.014
innate immune responseGO:00450871780.014
regulation of cell growthGO:00015581350.014
protein localization to organelleGO:00333652800.014
cellular amide metabolic processGO:0043603690.014
peripheral nervous system developmentGO:000742220.014
purine ribonucleoside monophosphate metabolic processGO:00091671860.014
protein oligomerizationGO:00512591730.014
embryo developmentGO:00097901230.014
modification dependent macromolecule catabolic processGO:00436322120.014
small molecule catabolic processGO:0044282920.014
regulation of cellular response to stressGO:00801352440.014
protein homooligomerizationGO:00512601000.014
positive regulation of cysteine type endopeptidase activityGO:2001056790.014
peptidyl serine modificationGO:00182091060.014
response to oxygen containing compoundGO:19017003690.014
positive regulation of organelle organizationGO:00106381950.014
chromatin modificationGO:00165682980.014
chromatin organizationGO:00063253510.014
neural nucleus developmentGO:0048857470.014
regulation of cysteine type endopeptidase activity involved in apoptotic processGO:00432811160.013
taxisGO:00423301570.013
defense responseGO:00069523150.013
axon cargo transportGO:000808820.013
tube closureGO:006060630.013
organic acid catabolic processGO:0016054710.013
negative regulation of phosphorylationGO:00423261740.013
microtubule cytoskeleton organizationGO:00002261760.013
regulation of cell morphogenesisGO:00226041530.013
neurotrophin trk receptor signaling pathwayGO:004801140.013
positive regulation of cysteine type endopeptidase activity involved in apoptotic processGO:0043280690.013
negative regulation of cell cycleGO:00457861930.013
macromolecule glycosylationGO:0043413630.013
single organism reproductive processGO:0044702980.013
positive regulation of immune system processGO:00026842830.013
establishment or maintenance of apical basal cell polarityGO:003508820.013
positive regulation of intrinsic apoptotic signaling pathwayGO:2001244280.013
ribonucleoside triphosphate catabolic processGO:00092033910.013
organic hydroxy compound biosynthetic processGO:1901617710.013
fatty acid metabolic processGO:00066311150.013
regenerationGO:003109940.013
neuron developmentGO:00486661130.013
positive regulation of reactive oxygen species metabolic processGO:2000379240.013
neurogenesisGO:00220081690.013
brain developmentGO:0007420970.013
cell projection morphogenesisGO:00488581290.012
regulation of i kappab kinase nf kappab signalingGO:00431221620.012
photoreceptor cell differentiationGO:004653020.012
regulation of mitochondrion organizationGO:0010821540.012
release of cytochrome c from mitochondriaGO:0001836350.012
response to radiationGO:00093141510.012
cardiac muscle cell contractionGO:008600340.012
nuclear transportGO:00511691790.012
nucleocytoplasmic transportGO:00069131760.012
head developmentGO:00603221080.012
atp catabolic processGO:00062001570.012
regulation of cell adhesionGO:00301551660.012
mitochondrion organizationGO:00070051560.012
transition metal ion transportGO:0000041230.012
regulation of meiotic cell cycleGO:005144540.012
positive regulation of synaptic transmissionGO:005080640.012
protein importGO:00170381300.012
alcohol biosynthetic processGO:0046165520.012
negative regulation of programmed cell deathGO:00430693210.012
actin filament based movementGO:0030048170.012
regulation of sequence specific dna binding transcription factor activityGO:00510902110.012
regulation of cellular component biogenesisGO:00440872810.012
carboxylic acid biosynthetic processGO:0046394970.012
somitogenesisGO:000175620.012
negative regulation of hydrolase activityGO:00513461820.012
cell morphogenesis involved in differentiationGO:00009041440.012
exocytosisGO:0006887710.012
agingGO:0007568660.012
negative regulation of protein phosphorylationGO:00019331400.012
covalent chromatin modificationGO:00165692540.012
ceramide metabolic processGO:0006672250.012
cell cell signalingGO:00072671550.012
cell activationGO:00017752130.012
fatty acid transportGO:0015908250.011
negative regulation of multicellular organismal processGO:00512413170.011
neural tube closureGO:000184330.011
purine ribonucleotide catabolic processGO:00091544040.011
mapk cascadeGO:00001652880.011
purine nucleoside catabolic processGO:00061523980.011
cytokine productionGO:00018162470.011
maintenance of cell polarityGO:003001120.011
establishment of protein localization to plasma membraneGO:0090002680.011
hindbrain developmentGO:003090230.011
wnt signaling pathwayGO:00160551560.011
very long chain fatty acid catabolic processGO:004276030.011
neurotransmitter secretionGO:000726940.011
ribonucleoside monophosphate metabolic processGO:00091611870.011
neural tube patterningGO:002153220.011
motor neuron axon guidanceGO:000804520.011
regulation of establishment of protein localizationGO:00702012420.011
circadian behaviorGO:004851220.011
nucleoside catabolic processGO:00091644080.011
response to light stimulusGO:0009416870.011
negative regulation of developmental processGO:00510932470.011
embryonic morphogenesisGO:0048598850.011
response to extracellular stimulusGO:0009991850.011
purine ribonucleoside triphosphate catabolic processGO:00092073910.011
negative regulation of cell deathGO:00605483450.011
carboxylic acid catabolic processGO:0046395710.011
sensory perceptionGO:00076001030.011
regulation of response to external stimulusGO:00321012220.011
regulation of multi organism processGO:00439001570.011
response to hormoneGO:00097251750.011
cofactor metabolic processGO:0051186870.011
coenzyme metabolic processGO:0006732650.011
regulation of hormone levelsGO:00108171250.011
negative regulation of proteolysisGO:00458611320.011
phosphatidylinositol metabolic processGO:0046488530.011
positive regulation of cellular component movementGO:00512721810.011
memoryGO:000761330.011
cell projection assemblyGO:00300311260.011
cell junction organizationGO:0034330790.011
positive regulation of cell migrationGO:00303351720.010
generation of neuronsGO:00486991520.010
actin cytoskeleton organizationGO:00300362070.010
protein glycosylationGO:0006486620.010
angiogenesisGO:00015251470.010
regulation of cell cycle phase transitionGO:19019871260.010
negative regulation of protein serine threonine kinase activityGO:0071901570.010
viral life cycleGO:00190581320.010
positive regulation of i kappab kinase nf kappab signalingGO:00431231320.010
growthGO:00400072020.010
tissue morphogenesisGO:0048729960.010
negative regulation of protein maturationGO:19033181420.010
monocarboxylic acid transportGO:0015718320.010
cellular response to growth factor stimulusGO:00713631970.010
regulation of transferase activityGO:00513383550.010
positive regulation of secretion by cellGO:19035321080.010
regulation of intracellular protein transportGO:00331571230.010
ribonucleoside monophosphate catabolic processGO:00091581580.010
response to inorganic substanceGO:00100351270.010
cellular macromolecular complex assemblyGO:00346223240.010
regulation of kinase activityGO:00435493140.010
sphingolipid metabolic processGO:0006665380.010
tissue migrationGO:00901301190.010
regulation of vesicle mediated transportGO:00606271300.010
tube developmentGO:00352951250.010

PTPLB disease predictions

DiseaseDO term IDSizeProbabilityFunc Analog Org
inherited metabolic disorderDOID:6552420.094
disease of metabolismDOID:00146672950.094
disease of cellular proliferationDOID:145661740.020
cancerDOID:1621670.020
organ system cancerDOID:00506861640.020
carbohydrate metabolic disorderDOID:2978550.020
nervous system diseaseDOID:8634310.016
central nervous system diseaseDOID:3311860.016
congenital disorder of glycosylationDOID:5212260.016
musculoskeletal system diseaseDOID:172230.015
neuropathyDOID:870520.013
immune system diseaseDOID:29141550.011
sensory system diseaseDOID:00501552030.011
disease of mental healthDOID:150700.011