Homo sapiens

0 known processes

GBP2

guanylate binding protein 2, interferon-inducible

(Aliases: DKFZp451C2311)

GBP2 biological process predictions


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Biological processGO term IDProcess sizeProbabilityFunc Analog Org
defense responseGO:00069523150.645
Mouse
response to biotic stimulusGO:00096072760.635
Mouse
immune responseGO:00069553070.621
Mouse
protein maturationGO:00516042330.615
defense response to other organismGO:00985421290.557
Mouse
response to external biotic stimulusGO:00432072610.537
Mouse
negative regulation of catalytic activityGO:00430863350.443
immune effector processGO:00022521590.435
negative regulation of hydrolase activityGO:00513461820.408
i kappab kinase nf kappab signalingGO:00072491660.395
regulation of endopeptidase activityGO:00525481700.386
positive regulation of cell deathGO:00109422630.383
regulation of immune responseGO:00507762010.363
negative regulation of peptidase activityGO:0010466910.361
response to other organismGO:00517072610.341
Mouse
cellular response to mechanical stimulusGO:0071260390.340
negative regulation of protein metabolic processGO:00512483910.325
negative regulation of protein maturationGO:19033181420.311
response to cytokineGO:00340972320.308
Mouse
positive regulation of interleukin 1 beta secretionGO:0050718110.261
hemopoiesisGO:00300971800.259
negative regulation of cysteine type endopeptidase activityGO:2000117480.252
regulation of protein processingGO:00706131500.247
positive regulation of i kappab kinase nf kappab signalingGO:00431231320.246
positive regulation of programmed cell deathGO:00430682490.238
regulation of peptidase activityGO:00525471800.236
cell activationGO:00017752130.230
negative regulation of cell deathGO:00605483450.216
negative regulation of endopeptidase activityGO:0010951840.207
regulation of cysteine type endopeptidase activityGO:20001161270.206
hematopoietic or lymphoid organ developmentGO:00485341860.199
negative regulation of developmental processGO:00510932470.198
immune system developmentGO:00025201950.197
protein processingGO:00164852260.196
angiogenesisGO:00015251470.195
positive regulation of apoptotic processGO:00430652460.189
response to virusGO:00096151260.186
cytokine mediated signaling pathwayGO:00192211090.186
negative regulation of protein processingGO:00109551420.181
regulation of protein maturationGO:19033171500.181
cytokine productionGO:00018162470.179
regulation of proteolysisGO:00301622930.178
trail activated apoptotic signaling pathwayGO:003646240.165
positive regulation of immune responseGO:00507781590.164
regulation of establishment of protein localizationGO:00702012420.157
negative regulation of cysteine type endopeptidase activity involved in apoptotic processGO:0043154460.148
cellular amine metabolic processGO:0044106410.147
negative regulation of multicellular organismal processGO:00512413170.146
putrescine metabolic processGO:000944520.144
positive regulation of cellular component organizationGO:00511303760.139
negative regulation of proteolysisGO:00458611320.139
regulation of apoptotic signaling pathwayGO:20012331750.137
defense response to virusGO:0051607710.131
cardiovascular system developmentGO:00723582620.130
symbiosis encompassing mutualism through parasitismGO:00444031560.128
Mouse
defense response to bacteriumGO:0042742630.126
Mouse
cell cycle arrestGO:0007050710.126
amine metabolic processGO:0009308440.123
regulation of mononuclear cell proliferationGO:0032944650.122
regulation of cysteine type endopeptidase activity involved in apoptotic processGO:00432811160.120
response to bacteriumGO:00096171440.119
Mouse
positive regulation of peptidase activityGO:0010952880.112
cellular response to abiotic stimulusGO:00712141170.111
apoptotic signaling pathwayGO:00971902680.110
positive regulation of organelle organizationGO:00106381950.107
proteolysis involved in cellular protein catabolic processGO:00516032440.106
positive regulation of immune system processGO:00026842830.106
positive regulation of nf kappab transcription factor activityGO:0051092810.104
multicellular organismal agingGO:001025930.104
negative regulation of cell differentiationGO:00455961710.100
regulation of protein localizationGO:00328802960.097
circulatory system developmentGO:00723592620.097
determination of adult lifespanGO:000834020.094
positive regulation of developmental processGO:00510943140.093
negative regulation of programmed cell deathGO:00430693210.090
cellular response to interferon gammaGO:0071346240.090
Mouse
cellular macromolecule catabolic processGO:00442653800.089
ion transmembrane transportGO:00342203380.089
response to interferon gammaGO:0034341390.088
Mouse
polyamine metabolic processGO:000659540.088
regulation of cell differentiationGO:00455953930.086
regulation of cell cycleGO:00517263930.086
regulation of cell activationGO:00508651250.082
signal transduction in response to dna damageGO:0042770570.082
innate immune responseGO:00450871780.078
Mouse
dna damage response signal transduction by p53 class mediatorGO:0030330440.077
positive regulation of apoptotic signaling pathwayGO:2001235700.075
response to abiotic stimulusGO:00096283360.070
response to interferon betaGO:0035456110.070
Mouse
regulation of leukocyte activationGO:00026941150.069
leukocyte differentiationGO:0002521980.069
positive regulation of cysteine type endopeptidase activityGO:2001056790.068
cellular protein catabolic processGO:00442572610.066
secretionGO:00469032540.066
autophagic cell deathGO:004810230.066
regulation of protein transportGO:00512232130.065
positive regulation of cell differentiationGO:00455972110.065
system processGO:00030083490.065
regulation of innate immune responseGO:0045088970.064
negative regulation of cell proliferationGO:00082852280.064
regulation of secretionGO:00510461940.063
biological adhesionGO:00226103310.062
Mouse
response to tumor necrosis factorGO:0034612760.059
positive regulation of proteolysisGO:00458621420.059
regulation of cellular amino acid metabolic processGO:000652160.058
protein autoprocessingGO:001654040.058
cellular response to endogenous stimulusGO:00714953360.058
cellular amino acid metabolic processGO:00065201160.057
viral life cycleGO:00190581320.057
positive regulation of sequence specific dna binding transcription factor activityGO:00510911310.056
regulation of protein secretionGO:0050708860.056
regulation of lymphocyte activationGO:00512491030.056
nucleocytoplasmic transportGO:00069131760.056
response to mechanical stimulusGO:0009612510.055
positive regulation of protein complex assemblyGO:0031334860.055
cellular response to dna damage stimulusGO:00069743790.054
negative regulation of cellular protein metabolic processGO:00322693530.054
zymogen activationGO:0031638700.053
negative regulation of cell cycleGO:00457861930.053
response to organic cyclic compoundGO:00140702040.053
cellular response to cytokine stimulusGO:00713451810.052
Mouse
positive regulation of innate immune responseGO:0045089790.052
toxin transportGO:190199840.052
immune response activating signal transductionGO:0002757900.051
regulation of cellular ketone metabolic processGO:0010565500.050
regulation of cell adhesionGO:00301551660.050
activation of immune responseGO:00022531140.050
regulation of extrinsic apoptotic signaling pathwayGO:2001236850.050
leukocyte activationGO:00453211640.048
epithelium developmentGO:00604292270.048
multi organism metabolic processGO:0044033410.048
peptide metabolic processGO:0006518510.047
response to hormoneGO:00097251750.047
cytoplasmic transportGO:00164823790.046
myoblast fusionGO:000752010.046
negative regulation of apoptotic processGO:00430663160.046
interspecies interaction between organismsGO:00444191560.046
Mouse
intracellular protein transportGO:00068862700.045
positive regulation of cellular component biogenesisGO:00440891580.045
positive regulation of cytokine productionGO:00018191670.045
mitochondrion organizationGO:00070051560.044
cellular ketone metabolic processGO:0042180800.043
t cell proliferationGO:0042098450.043
regulation of cell cycle arrestGO:0071156360.043
cellular biogenic amine metabolic processGO:0006576340.042
multi organism cellular processGO:00447641560.042
negative regulation of protein deubiquitinationGO:009008630.042
cation transportGO:00068123310.041
immune response activating cell surface receptor signaling pathwayGO:0002429450.041
adaptive immune responseGO:0002250490.041
response to growth factorGO:00708482050.041
positive regulation of mitochondrion organizationGO:0010822300.040
negative regulation of mitotic cell cycleGO:00459301020.040
post embryonic developmentGO:000979120.040
apoptotic mitochondrial changesGO:0008637570.040
regulation of interleukin 1 productionGO:0032652210.040
protein localization to organelleGO:00333652800.040
protein targeting to nucleusGO:00447441040.039
secretion by cellGO:00329402260.037
mitotic cell cycle processGO:19030472860.037
negative regulation of transportGO:00510511760.037
regulation of i kappab kinase nf kappab signalingGO:00431221620.037
protein targetingGO:00066051870.037
protein catabolic processGO:00301633250.037
immune response regulating signaling pathwayGO:0002764970.037
posttranscriptional regulation of gene expressionGO:00106082130.037
cell adhesionGO:00071553250.037
positive regulation of secretionGO:00510471160.037
lymphocyte activationGO:00466491330.037
mitotic cell cycle phase transitionGO:00447721620.036
anatomical structure formation involved in morphogenesisGO:00486462840.036
cellular response to hormone stimulusGO:00328701250.036
g1 s transition of mitotic cell cycleGO:0000082780.035
rhythmic behaviorGO:000762220.035
calcium ion transportGO:00068161470.035
t cell activationGO:0042110990.035
positive regulation of humoral immune responseGO:000292230.035
cell cycle phase transitionGO:00447701730.035
activation of innate immune responseGO:0002218550.035
regulation of cell migrationGO:00303342890.034
positive regulation of defense responseGO:0031349870.034
cellular response to external stimulusGO:00714961110.034
regulation of interleukin 1 secretionGO:0050704140.033
regulation of mitotic cell cycleGO:00073461890.033
spermidine metabolic processGO:000821630.033
sequestering of metal ionGO:0051238240.033
regulation of viral processGO:00507921030.032
regulation of t cell proliferationGO:0042129420.032
regulation of immune effector processGO:0002697910.032
regulation of response to external stimulusGO:00321012220.032
mitotic cell cycleGO:00002783260.031
ras protein signal transductionGO:0007265730.031
leukocyte mediated immunityGO:0002443590.031
cellular response to lipidGO:00713961270.030
Mouse
regulation of lymphocyte proliferationGO:0050670640.030
regulation of cytokine productionGO:00018172320.030
regulation of cell cycle phase transitionGO:19019871260.030
cellular response to growth factor stimulusGO:00713631970.030
negative regulation of intracellular signal transductionGO:19025321830.029
nucleotide catabolic processGO:00091664080.029
positive regulation of response to external stimulusGO:0032103880.029
cytolysisGO:001983580.029
neurological system processGO:00508771630.029
melanin metabolic processGO:000658210.029
regulation of transferase activityGO:00513383550.029
regulation of calcium ion transportGO:0051924790.029
developmental programmed cell deathGO:001062330.029
neuron projection regenerationGO:003110210.029
positive regulation of transportGO:00510503360.029
cellular response to radiationGO:0071478650.029
metal ion transportGO:00300012720.029
purine containing compound catabolic processGO:00725234110.029
positive regulation of protein transportGO:00512221350.029
mononuclear cell proliferationGO:0032943710.029
syncytium formation by plasma membrane fusionGO:000076820.028
extrinsic apoptotic signaling pathway via death domain receptorsGO:0008625420.028
response to woundingGO:00096111680.028
purine ribonucleoside triphosphate catabolic processGO:00092073910.028
regulation of cell cell adhesionGO:0022407570.028
regulation of cellular response to stressGO:00801352440.027
positive regulation of homotypic cell cell adhesionGO:003411240.027
regulation of interleukin 1 beta secretionGO:0050706120.027
myeloid cell differentiationGO:00300991170.027
nervous system developmentGO:00073992930.027
regulation of bindingGO:00510981110.026
detection of chemical stimulusGO:0009593550.026
regulation of anatomical structure morphogenesisGO:00226032860.026
positive regulation of secretion by cellGO:19035321080.026
spermatid developmentGO:000728640.026
regulation of leukocyte differentiationGO:1902105610.025
signal transduction by p53 class mediatorGO:0072331720.025
regulation of cell cycle processGO:00105642660.025
cd8 positive alpha beta t cell activationGO:003603730.025
extrinsic apoptotic signaling pathwayGO:00971911190.025
regulation of cytoplasmic transportGO:19036491490.025
regulation of ion transmembrane transportGO:00347651320.025
signal transduction by phosphorylationGO:00230142970.024
positive regulation of cell cycleGO:00457871400.024
release of cytochrome c from mitochondriaGO:0001836350.024
negative regulation of cellular component movementGO:00512711060.024
regulation of intracellular transport of viral materialGO:190125220.024
regulation of cellular amine metabolic processGO:0033238110.023
positive regulation of leukocyte activationGO:0002696800.023
positive regulation of leukocyte differentiationGO:1902107370.023
positive regulation of phosphorylationGO:00423273940.023
divalent inorganic cation transportGO:00725111580.023
regulation of leukocyte proliferationGO:0070663670.023
regulation of secretion by cellGO:19035301770.023
protein secretionGO:0009306980.023
regulation of membrane potentialGO:0042391950.023
spermatid differentiationGO:004851540.022
reactive oxygen species metabolic processGO:0072593750.022
nuclear transportGO:00511691790.022
cellular response to organic cyclic compoundGO:00714071270.022
embryonic organ developmentGO:0048568360.022
transmembrane transportGO:00550853990.022
t cell selectionGO:004505840.022
negative regulation of intracellular protein transportGO:0090317420.022
regulation of transmembrane transportGO:00347621390.022
mapk cascadeGO:00001652880.022
humoral immune responseGO:0006959490.022
neuron remodelingGO:001632220.021
regulation of intracellular protein transportGO:00331571230.021
protein modification by small protein conjugationGO:00324463420.021
mitochondrial fragmentation involved in apoptotic processGO:004365370.021
positive regulation of leukocyte proliferationGO:0070665480.021
regulation of protein targetingGO:1903533910.021
response to organonitrogen compoundGO:00102431560.020
pattern recognition receptor signaling pathwayGO:0002221480.020
negative regulation of protein transportGO:0051224750.020
regulation of defense responseGO:00313471540.020
mitochondrial transportGO:0006839600.020
regulation of antimicrobial humoral responseGO:000275910.020
chromatin modificationGO:00165682980.020
response to molecule of bacterial originGO:0002237820.020
Mouse
vasculature developmentGO:00019441810.020
immune response regulating cell surface receptor signaling pathwayGO:0002768510.019
circadian behaviorGO:004851220.019
defense response to gram positive bacteriumGO:0050830290.019
Mouse
establishment of protein localization to membraneGO:00901501210.019
circadian sleep wake cycle processGO:002241020.019
regenerationGO:003109940.019
positive regulation of endopeptidase activityGO:0010950840.019
membrane hyperpolarizationGO:006008110.019
negative regulation of nucleocytoplasmic transportGO:0046823370.019
positive regulation of release of cytochrome c from mitochondriaGO:0090200180.019
regulation of behaviorGO:0050795820.019
regulation of defense response to virusGO:0050688330.018
membrane organizationGO:00610242920.018
myeloid leukocyte differentiationGO:0002573600.018
locomotory behaviorGO:000762610.018
positive regulation of hydrolase activityGO:00513453310.018
pyroptosisGO:007026910.018
organonitrogen compound biosynthetic processGO:19015662000.018
negative regulation of viral transcriptionGO:0032897230.018
positive regulation of mitochondrial membrane permeabilityGO:0035794170.018
positive regulation of cellular amino acid metabolic processGO:004576430.018
regulation of mitochondrial membrane permeability involved in apoptotic processGO:1902108180.018
female gamete generationGO:000729220.018
negative regulation of cell cycle processGO:00109481210.017
regulation of system processGO:00440571010.017
single organism membrane organizationGO:00448022680.017
central nervous system developmentGO:00074171230.017
circulatory system processGO:00030131130.017
response to estrogenGO:0043627470.017
transmembrane receptor protein tyrosine kinase signaling pathwayGO:00071691810.017
negative regulation of vasculature developmentGO:1901343430.017
protein localization to membraneGO:00726571600.017
positive regulation of kinase activityGO:00336742040.017
regulation of t cell activationGO:0050863770.017
cell developmentGO:00484683280.017
regulation of response to biotic stimulusGO:0002831550.017
protein ubiquitinationGO:00165673140.016
regulation of protein localization to nucleusGO:1900180850.016
activation of cysteine type endopeptidase activity involved in apoptotic processGO:0006919490.016
peripheral nervous system developmentGO:000742220.016
regulation of release of cytochrome c from mitochondriaGO:0090199290.016
positive regulation of interferon gamma productionGO:0032729260.016
glycosyl compound catabolic processGO:19016584130.016
negative regulation of intracellular transportGO:0032387600.016
cell morphogenesisGO:00009022960.016
neuron developmentGO:00486661130.016
positive regulation of cellular amine metabolic processGO:003324070.016
cell cycle checkpointGO:00000751170.016
positive regulation of protein secretionGO:0050714600.015
regulation of vasculature developmentGO:1901342970.015
negative regulation of protein modification processGO:00314002000.015
midgut developmentGO:000749410.015
protein modification by small protein removalGO:0070646920.015
protein oligomerizationGO:00512591730.015
compound eye developmentGO:004874910.015
protein import into nucleusGO:00066061040.015
negative regulation of mitochondrial fusionGO:001063740.015
regulation of multi organism processGO:00439001570.015
positive regulation of lymphocyte activationGO:0051251730.015
regulation of interferon gamma productionGO:0032649360.015
regulation of protein import into nucleusGO:0042306780.015
blood circulationGO:00080151130.015
cytokine secretionGO:0050663640.015
ribonucleotide catabolic processGO:00092614050.015
ribonucleoside triphosphate catabolic processGO:00092033910.015
regulation of metal ion transportGO:00109591200.014
positive regulation of cellular catabolic processGO:00313312840.014
negative regulation of cytoplasmic transportGO:1903650460.014
regulation of dna metabolic processGO:00510521530.014
positive regulation of intracellular transportGO:00323881040.014
cellular response to interleukin 1GO:0071347350.014
generation of neuronsGO:00486991520.014
negative regulation of bindingGO:0051100570.014
viral genome replicationGO:0019079500.014
negative regulation of lymphocyte activationGO:0051250240.014
cellular response to oxidative stressGO:0034599850.014
t cell differentiation in thymusGO:003307740.014
cell fate determinationGO:000170930.014
response to cobalt ionGO:003202510.014
positive regulation of mononuclear cell proliferationGO:0032946470.014
blood vessel morphogenesisGO:00485141620.014
negative regulation of blood vessel morphogenesisGO:2000181410.013
cellular response to steroid hormone stimulusGO:0071383370.013
negative regulation of angiogenesisGO:0016525390.013
chloride transportGO:0006821410.013
purine ribonucleotide catabolic processGO:00091544040.013
ribonucleoside catabolic processGO:00424544060.013
cellular amide metabolic processGO:0043603690.013
cell cycle g1 s phase transitionGO:0044843800.013
regulation of cd8 positive alpha beta t cell proliferationGO:200056410.013
intrinsic apoptotic signaling pathway in response to dna damageGO:0008630500.013
positive regulation of myeloid cell differentiationGO:0045639390.013
purine nucleoside triphosphate metabolic processGO:00091444120.013
positive regulation of cell proliferationGO:00082843010.013
lymphocyte proliferationGO:0046651700.013
multicellular organismal metabolic processGO:0044236340.013
negative regulation of cellular component organizationGO:00511292350.013
regulation of nucleocytoplasmic transportGO:0046822980.013
negative regulation of immune responseGO:0050777400.013
inorganic anion transmembrane transportGO:0098661470.013
negative regulation of phosphate metabolic processGO:00459362670.013
positive regulation of interleukin 1 beta productionGO:0032731130.013
regulation of myeloid leukocyte differentiationGO:0002761390.013
establishment of protein localization to organelleGO:00725941720.013
cellular response to uvGO:0034644320.012
regulation of viral transcriptionGO:0046782340.012
mitochondrial outer membrane permeabilizationGO:0097345150.012
endosomal transportGO:00161971290.012
regulation of kinase activityGO:00435493140.012
memoryGO:000761330.012
regulation of nucleoside metabolic processGO:00091182090.012
regulation of mitochondrion organizationGO:0010821540.012
blood vessel developmentGO:00015681720.012
multicellular organismal catabolic processGO:0044243120.012
inorganic ion transmembrane transportGO:00986602310.012
organelle fusionGO:0048284360.012
regulation of sequence specific dna binding transcription factor activityGO:00510902110.012
negative regulation of cell cycle phase transitionGO:1901988890.012
execution phase of apoptosisGO:0097194320.012
single organism nuclear importGO:19025931040.012
lymphocyte differentiationGO:0030098350.012
signal transduction involved in cell cycle checkpointGO:0072395160.012
regulation of syncytium formation by plasma membrane fusionGO:006014220.012
positive regulation of antimicrobial humoral responseGO:000276010.012
negative regulation of blood circulationGO:190352340.012
positive regulation of type i interferon productionGO:0032481200.012
small gtpase mediated signal transductionGO:0007264780.012
response to inorganic substanceGO:00100351270.012
translationGO:00064121320.012
positive regulation of viral processGO:0048524370.012
divalent metal ion transportGO:00708381520.012
negative regulation of cell activationGO:0050866330.012
autophagyGO:0006914880.012
nucleoside triphosphate catabolic processGO:00091433940.012
response to radiationGO:00093141510.011
regulation of heart contractionGO:0008016500.011
vesicle mediated transportGO:00161923710.011
ubiquitin dependent protein catabolic processGO:00065112060.011
activation of cysteine type endopeptidase activityGO:0097202570.011
stress activated protein kinase signaling cascadeGO:0031098940.011
collagen metabolic processGO:0032963280.011
cellular response to lipopolysaccharideGO:0071222570.011
Mouse
cellular response to molecule of bacterial originGO:0071219620.011
Mouse
negative regulation of extrinsic apoptotic signaling pathwayGO:2001237520.011
negative regulation of transcription from rna polymerase ii promoterGO:00001222810.011
purine nucleoside triphosphate catabolic processGO:00091463920.011
single organism cellular localizationGO:19025803320.011
regulation of intracellular transportGO:00323861950.011
positive regulation of cysteine type endopeptidase activity involved in apoptotic signaling pathwayGO:200126910.011
ossificationGO:00015031210.011
osteoblast differentiationGO:0001649920.011
protein importGO:00170381300.011
response to ionizing radiationGO:0010212650.011
negative regulation of cellular catabolic processGO:0031330830.011
regulation of membrane permeabilityGO:0090559250.011
negative regulation of immune effector processGO:0002698380.011
positive regulation of cell cycle arrestGO:0071158230.011
jnk cascadeGO:0007254800.011
positive regulation of immune effector processGO:0002699400.011
response to metal ionGO:0010038840.011
membrane fusionGO:0061025430.011
neuron differentiationGO:00301821380.011
organophosphate catabolic processGO:00464344300.011
response to nitrogen compoundGO:19016981840.011
regulation of symbiosis encompassing mutualism through parasitismGO:00439031090.011
erk1 and erk2 cascadeGO:00703711040.010
negative regulation of phosphorus metabolic processGO:00105632670.010
regulation of mapk cascadeGO:00434082620.010
positive regulation of cysteine type endopeptidase activity involved in apoptotic processGO:0043280690.010
lymphocyte homeostasisGO:000226040.010
calcium ion importGO:0070509230.010
negative regulation of phosphorylationGO:00423261740.010
regulation of cellular component biogenesisGO:00440872810.010
regulation of dna bindingGO:0051101370.010
purine nucleotide catabolic processGO:00061954050.010
cellular response to metal ionGO:0071248430.010
positive regulation of multi organism processGO:0043902560.010
anatomical structure homeostasisGO:00602491000.010
leukocyte proliferationGO:0070661740.010
negative regulation of protein phosphorylationGO:00019331400.010
regulation of protein catabolic processGO:00421761550.010
multicellular organismal homeostasisGO:0048871670.010

GBP2 disease predictions

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of cellular proliferationDOID:145661740.022
organ system cancerDOID:00506861640.019
cancerDOID:1621670.019