Homo sapiens

7 known processes

OTOF

otoferlin

(Aliases: NSRD9,DFNB9,FER1L2,DFNB6,AUNB1)

OTOF biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
transmembrane transportGO:00550853990.190
cation transportGO:00068123310.165
metal ion transportGO:00300012720.138
ion transmembrane transportGO:00342203380.118
g protein coupled receptor signaling pathwayGO:00071862070.115
cation transmembrane transportGO:00986552380.107
inorganic ion transmembrane transportGO:00986602310.098
system processGO:00030083490.088
chemical homeostasisGO:00488783060.088
inorganic cation transmembrane transportGO:00986621940.087
regulation of ion transportGO:00432691890.087
positive regulation of transportGO:00510503360.074
ion homeostasisGO:00508012300.073
cellular ketone metabolic processGO:0042180800.070
regulation of cellular amino acid metabolic processGO:000652160.063
cellular amine metabolic processGO:0044106410.059
post embryonic developmentGO:000979120.059
metal ion homeostasisGO:00550651690.056
positive regulation of phosphorylationGO:00423273940.055
locomotory behaviorGO:000762610.055
amine metabolic processGO:0009308440.055
positive regulation of cellular component organizationGO:00511303760.054
carbohydrate derivative biosynthetic processGO:19011372070.052
purine ribonucleotide catabolic processGO:00091544040.051
cell cell signalingGO:00072671550.051
Mouse
regulation of cellular ketone metabolic processGO:0010565500.050
response to abiotic stimulusGO:00096283360.049
divalent metal ion transportGO:00708381520.049
cellular divalent inorganic cation homeostasisGO:00725031280.048
cellular ion homeostasisGO:00068731680.048
secretionGO:00469032540.048
Mouse
actin filament based movementGO:0030048170.047
biological adhesionGO:00226103310.047
regulation of cellular amine metabolic processGO:0033238110.047
homeostasis of number of cells in a free living populationGO:004887410.044
muscle contractionGO:0006936730.044
negative regulation of multicellular organismal processGO:00512413170.044
immune responseGO:00069553070.044
actin mediated cell contractionGO:0070252120.043
cellular cation homeostasisGO:00300031630.043
cation homeostasisGO:00550801890.043
anion transportGO:00068201610.042
calcium ion transportGO:00068161470.042
regulation of transferase activityGO:00513383550.040
cellular amino acid metabolic processGO:00065201160.039
cellular homeostasisGO:00197251960.039
organophosphate catabolic processGO:00464344300.039
purine containing compound catabolic processGO:00725234110.038
cytoplasmic transportGO:00164823790.038
purine nucleoside triphosphate metabolic processGO:00091444120.038
cell adhesionGO:00071553250.037
regulation of metal ion transportGO:00109591200.037
divalent inorganic cation homeostasisGO:00725071360.037
divalent inorganic cation transportGO:00725111580.037
vesicle mediated transportGO:00161923710.036
Mouse
neurological system processGO:00508771630.036
response to oxygen containing compoundGO:19017003690.036
regulation of secretion by cellGO:19035301770.036
cellular chemical homeostasisGO:00550821800.035
positive regulation of cellular amino acid metabolic processGO:004576430.035
secretion by cellGO:00329402260.034
Mouse
ribonucleotide catabolic processGO:00092614050.034
regulation of anatomical structure morphogenesisGO:00226032860.033
nucleoside triphosphate metabolic processGO:00091414220.033
nucleoside phosphate catabolic processGO:19012924120.033
regulation of ion transmembrane transportGO:00347651320.033
cellular metal ion homeostasisGO:00068751460.033
urate transportGO:001574730.033
ribonucleoside triphosphate catabolic processGO:00092033910.032
purine nucleoside triphosphate catabolic processGO:00091463920.032
blood circulationGO:00080151130.032
negative regulation of catalytic activityGO:00430863350.032
regulation of kinase activityGO:00435493140.032
memoryGO:000761330.031
alpha ketoglutarate transportGO:001574210.031
ribonucleoside triphosphate metabolic processGO:00091994120.031
negative regulation of transportGO:00510511760.031
purine ribonucleoside triphosphate metabolic processGO:00092054110.031
response to biotic stimulusGO:00096072760.031
determination of adult lifespanGO:000834020.031
sensory perception of light stimulusGO:0050953350.030
multicellular organismal agingGO:001025930.030
cardiac muscle cell contractionGO:008600340.030
defense responseGO:00069523150.030
protein localization to organelleGO:00333652800.030
purine nucleoside catabolic processGO:00061523980.029
ras protein signal transductionGO:0007265730.029
positive regulation of mapk cascadeGO:00434101900.029
cellular response to oxygen containing compoundGO:19017012760.029
regulation of establishment of protein localizationGO:00702012420.029
regulation of protein kinase activityGO:00458592890.029
sensory perceptionGO:00076001030.029
regulation of transmembrane transportGO:00347621390.029
positive regulation of immune system processGO:00026842830.028
regulation of protein transportGO:00512232130.028
purine ribonucleoside metabolic processGO:00461284370.028
rho protein signal transductionGO:0007266260.027
small gtpase mediated signal transductionGO:0007264780.027
regulation of secretionGO:00510461940.027
associative learningGO:000830610.027
intracellular protein transportGO:00068862700.027
carnitine transmembrane transportGO:190260330.027
positive regulation of cell proliferationGO:00082843010.027
regulation of purine nucleotide metabolic processGO:19005422640.027
nucleotide catabolic processGO:00091664080.027
regulation of protein localizationGO:00328802960.027
adult locomotory behaviorGO:000834410.027
vasculature developmentGO:00019441810.027
nucleoside triphosphate catabolic processGO:00091433940.027
response to external biotic stimulusGO:00432072610.027
actin filament based processGO:00300292240.026
calcium ion transmembrane transportGO:0070588760.026
regulation of intracellular transportGO:00323861950.026
glycosyl compound catabolic processGO:19016584130.026
purine ribonucleoside triphosphate catabolic processGO:00092073910.025
response to other organismGO:00517072610.025
segmentationGO:003528240.025
signal transduction by phosphorylationGO:00230142970.025
ribonucleoside catabolic processGO:00424544060.025
hindbrain developmentGO:003090230.025
positive regulation of cellular amine metabolic processGO:003324070.025
positive regulation of transferase activityGO:00513472270.025
mapk cascadeGO:00001652880.025
positive regulation of kinase activityGO:00336742040.025
positive regulation of digestive system processGO:006045620.025
cellular calcium ion homeostasisGO:00068741170.024
muscle system processGO:0003012810.024
cellular macromolecule catabolic processGO:00442653800.024
positive regulation of developmental processGO:00510943140.024
neuromuscular junction developmentGO:000752830.024
positive regulation of cell differentiationGO:00455972110.024
purine ribonucleoside catabolic processGO:00461303980.024
regulation of nucleotide metabolic processGO:00061402690.024
positive regulation of protein phosphorylationGO:00019343130.024
protein processingGO:00164852260.024
regulation of membrane potentialGO:0042391950.024
protein catabolic processGO:00301633250.023
regulation of cellular component biogenesisGO:00440872810.023
lipid metabolic processGO:00066293810.023
cellular macromolecular complex assemblyGO:00346223240.023
blastoderm segmentationGO:000735020.023
regulation of system processGO:00440571010.023
startle responseGO:000196430.023
calcium ion homeostasisGO:00550741220.022
regulation of cytokine productionGO:00018172320.022
purine nucleotide catabolic processGO:00061954050.022
negative regulation of cellular protein metabolic processGO:00322693530.022
regulation of cell cycleGO:00517263930.022
regulation of cell differentiationGO:00455953930.022
positive regulation of cytokine productionGO:00018191670.022
female gamete generationGO:000729220.022
protein maturationGO:00516042330.022
nitrogen compound transportGO:00717051910.022
negative regulation of phosphorus metabolic processGO:00105632670.021
response to organonitrogen compoundGO:00102431560.021
short chain fatty acid transportGO:001591210.021
negative regulation of cellular amino acid metabolic processGO:004576320.021
negative regulation of cellular amine metabolic processGO:003323930.021
positive regulation of intestinal epithelial structure maintenanceGO:006073110.021
cardiovascular system developmentGO:00723582620.021
regulation of cell adhesionGO:00301551660.021
metencephalon developmentGO:002203720.021
mitotic cell cycleGO:00002783260.021
striated muscle contractionGO:0006941520.021
single organism cellular localizationGO:19025803320.021
positive regulation of hydrolase activityGO:00513453310.021
positive regulation of protein kinase activityGO:00458601900.021
organophosphate biosynthetic processGO:00904071630.021
membrane organizationGO:00610242920.021
chromatin organizationGO:00063253510.020
short chain fatty acid importGO:001591310.020
monovalent inorganic cation transportGO:00156721280.020
nicotinate transportGO:200114210.020
interspecies quorum sensingGO:005209710.020
negative regulation of phosphate metabolic processGO:00459362670.020
single organism cell adhesionGO:00986021790.020
response to radiationGO:00093141510.020
nervous system developmentGO:00073992930.020
single organism membrane organizationGO:00448022680.020
anatomical structure formation involved in morphogenesisGO:00486462840.020
oogenesisGO:004847720.020
cyclic nucleotide metabolic processGO:0009187820.020
quorum sensing involved in interaction with hostGO:005210610.020
regulation of protein serine threonine kinase activityGO:00719001790.020
cellular lipid metabolic processGO:00442553030.020
negative regulation of cellular component organizationGO:00511292350.020
cardiac muscle contractionGO:0060048340.019
protein targetingGO:00066051870.019
positive regulation of cell deathGO:00109422630.019
regulation of cytoplasmic transportGO:19036491490.019
innate immune responseGO:00450871780.019
regulation of homeostatic processGO:00328441210.019
cellular protein catabolic processGO:00442572610.019
response to lipidGO:00339932060.019
cell developmentGO:00484683280.019
negative regulation of protein metabolic processGO:00512483910.019
positive regulation of organelle organizationGO:00106381950.019
anterior posterior axis specificationGO:000994820.019
cellular response to dna damage stimulusGO:00069743790.019
positive regulation of catabolic processGO:00098963100.019
nucleoside phosphate biosynthetic processGO:19012931090.019
dephosphorylationGO:00163112090.019
cellular component morphogenesisGO:00329893140.019
regulation of mapk cascadeGO:00434082620.019
nucleotide biosynthetic processGO:00091651090.019
detection of stimulusGO:0051606850.019
positive regulation of purine nucleotide metabolic processGO:19005442270.019
proteolysis involved in cellular protein catabolic processGO:00516032440.019
regulation of vesicle mediated transportGO:00606271300.019
anion transmembrane transportGO:0098656760.018
growthGO:00400072020.018
regulation of locomotionGO:00400123290.018
visual learningGO:000854210.018
purine nucleotide biosynthetic processGO:0006164840.018
regulation of response to external stimulusGO:00321012220.018
positive regulation of apoptotic processGO:00430652460.018
regulation of sequence specific dna binding transcription factor activityGO:00510902110.018
negative regulation of apoptotic processGO:00430663160.018
apoptotic signaling pathwayGO:00971902680.018
cell projection organizationGO:00300302520.018
nucleoside catabolic processGO:00091644080.018
regulation of muscle system processGO:0090257530.018
negative regulation of programmed cell deathGO:00430693210.018
regulation of immune responseGO:00507762010.018
chromatin modificationGO:00165682980.018
regulation of calcium ion transportGO:0051924790.018
cell activationGO:00017752130.018
cellular protein complex assemblyGO:00436231880.018
quorum sensingGO:000937210.018
anatomical structure homeostasisGO:00602491000.017
cell morphogenesisGO:00009022960.017
endomembrane system organizationGO:00102561960.017
cerebellum developmentGO:002154920.017
response to organic cyclic compoundGO:00140702040.017
mitotic cell cycle processGO:19030472860.017
blood vessel developmentGO:00015681720.017
response to light stimulusGO:0009416870.017
protein ubiquitinationGO:00165673140.017
regulation of cell developmentGO:00602841610.017
matingGO:000761810.017
multicellular organismal homeostasisGO:0048871670.017
regulation of cell cycle processGO:00105642660.017
response to virusGO:00096151260.017
epithelium developmentGO:00604292270.017
lipid localizationGO:00108761060.017
positive regulation of protein transportGO:00512221350.017
regulation of proteolysisGO:00301622930.017
cytokine productionGO:00018162470.017
protein oligomerizationGO:00512591730.017
protein modification by small protein conjugationGO:00324463420.017
regulation of growthGO:00400081650.017
regulation of hormone levelsGO:00108171250.017
renal tubular secretionGO:009725410.017
nuclear transportGO:00511691790.017
cellular response to abiotic stimulusGO:00712141170.017
peptidyl tyrosine modificationGO:00182121700.017
nucleocytoplasmic transportGO:00069131760.017
purine ribonucleoside monophosphate metabolic processGO:00091671860.017
regulation of cytoskeleton organizationGO:00514931770.016
lipid transportGO:0006869900.016
sodium ion transportGO:0006814610.016
compound eye developmentGO:004874910.016
sodium independent organic anion transportGO:004325220.016
circadian behaviorGO:004851220.016
organonitrogen compound biosynthetic processGO:19015662000.016
regulation of cellular response to stressGO:00801352440.016
response to nitrogen compoundGO:19016981840.016
organic anion transportGO:00157111030.016
positive regulation of nucleotide metabolic processGO:00459812300.016
cytosolic calcium ion homeostasisGO:0051480890.016
positive regulation of ion transportGO:0043270870.016
positive regulation of cellular catabolic processGO:00313312840.016
negative regulation of cell deathGO:00605483450.016
ossificationGO:00015031210.016
microtubule based processGO:00070172100.016
single organismal cell cell adhesionGO:00163371480.016
visual perceptionGO:0007601270.016
sequestering of metal ionGO:0051238240.016
positive regulation of cytosolic calcium ion concentrationGO:0007204820.016
regulation of cellular component movementGO:00512703340.016
limbic system developmentGO:002176130.016
copulationGO:000762010.015
positive regulation of programmed cell deathGO:00430682490.015
cell growthGO:00160491600.015
reactive oxygen species biosynthetic processGO:190340940.015
establishment of protein localization to organelleGO:00725941720.015
regulation of actin filament based processGO:00329701410.015
positive regulation of immune responseGO:00507781590.015
sodium dependent organic cation transportGO:007071510.015
organelle assemblyGO:00709251760.015
modification dependent protein catabolic processGO:00199412090.015
actin cytoskeleton organizationGO:00300362070.015
guanosine containing compound metabolic processGO:19010682440.015
regulation of synaptic plasticityGO:004816730.015
purine containing compound biosynthetic processGO:0072522880.015
covalent chromatin modificationGO:00165692540.015
positive regulation of secretion by cellGO:19035321080.015
atp metabolic processGO:00460341760.015
regulation of postsynaptic membrane potentialGO:006007810.015
modification dependent macromolecule catabolic processGO:00436322120.015
negative regulation of protein modification processGO:00314002000.015
histone modificationGO:00165702510.015
negative regulation of cell differentiationGO:00455961710.015
regulation of ion homeostasisGO:2000021730.015
maintenance of locationGO:00512351120.014
regulation of purine nucleotide catabolic processGO:00331212050.014
positive regulation of synaptic transmissionGO:005080640.014
negative regulation of cell cycleGO:00457861930.014
glycoprotein metabolic processGO:00091001100.014
rhythmic behaviorGO:000762220.014
enzyme linked receptor protein signaling pathwayGO:00071673030.014
negative regulation of intracellular signal transductionGO:19025321830.014
carbohydrate metabolic processGO:00059752070.014
positive regulation of secretionGO:00510471160.014
cellular response to organonitrogen compoundGO:00714171240.014
visual behaviorGO:000763220.014
regulation of protein catabolic processGO:00421761550.014
regulation of peptidyl tyrosine phosphorylationGO:00507301080.014
negative regulation of hydrolase activityGO:00513461820.014
regulation of apoptotic signaling pathwayGO:20012331750.014
protein targeting to nucleusGO:00447441040.014
proteasome mediated ubiquitin dependent protein catabolic processGO:00431611560.014
guanosine containing compound catabolic processGO:19010692390.014
regulation of nucleotide catabolic processGO:00308112050.014
regulation of neurotransmitter secretionGO:004692830.014
protein localization to nucleusGO:00345041360.014
syncytium formation by plasma membrane fusionGO:000076820.014
response to bacteriumGO:00096171440.014
action potentialGO:0001508340.014
sensory perception of painGO:001923340.014
defense response to other organismGO:00985421290.014
gtp metabolic processGO:00460392390.014
cell substrate adhesionGO:00315891320.014
regulation of cell motilityGO:20001452990.014
regulation of mitotic cell cycleGO:00073461890.014
negative regulation of organelle organizationGO:00106391260.014
mitochondrion organizationGO:00070051560.014
sodium ion transmembrane transportGO:0035725590.014
regulation of gtpase activityGO:00430871800.014
circulatory system processGO:00030131130.013
regulation of cell growthGO:00015581350.013
cellular response to growth factor stimulusGO:00713631970.013
nuclear importGO:00511701060.013
ubiquitin dependent protein catabolic processGO:00065112060.013
sequestering of calcium ionGO:0051208170.013
cell divisionGO:00513011680.013
cell cycle phase transitionGO:00447701730.013
cellular response to endogenous stimulusGO:00714953360.013
purine nucleoside monophosphate metabolic processGO:00091261860.013
response to growth factorGO:00708482050.013
hormone transportGO:0009914680.013
purine ribonucleoside monophosphate catabolic processGO:00091691580.013
purine nucleoside monophosphate catabolic processGO:00091281580.013
wnt signaling pathwayGO:00160551560.013
positive regulation of calcium ion transportGO:0051928510.013
neurotransmitter secretionGO:000726940.013
Mouse
oocyte differentiationGO:000999420.013
protein homooligomerizationGO:00512601000.013
regulation of cell migrationGO:00303342890.013
regulation of reactive oxygen species biosynthetic processGO:190342630.013
ribonucleoside monophosphate metabolic processGO:00091611870.013
oocyte developmentGO:004859910.013
immune system developmentGO:00025201950.013
negative regulation of cell proliferationGO:00082852280.013
gtp catabolic processGO:00061842370.013
neuropeptide signaling pathwayGO:0007218190.013
oxidation reduction processGO:00551143960.013
tripartite regional subdivisionGO:000735120.013
ribose phosphate biosynthetic processGO:0046390820.013
positive regulation of cell motilityGO:20001471770.013
spermatid differentiationGO:004851540.013
small molecule biosynthetic processGO:00442831570.013
nucleoside monophosphate metabolic processGO:00091231910.013
response to cytokineGO:00340972320.013
regulation of defense responseGO:00313471540.013
canonical wnt signaling pathwayGO:00600701160.013
response to inorganic substanceGO:00100351270.013
response to fungusGO:000962040.013
epithelial cell differentiationGO:00308551410.013
mitotic cell cycle phase transitionGO:00447721620.013
proteasomal protein catabolic processGO:00104981760.012
microtubule cytoskeleton organizationGO:00002261760.012
organ formationGO:004864530.012
cellular response to nitrogen compoundGO:19016991440.012
post embryonic organ developmentGO:004856910.012
positive regulation of insulin like growth factor receptor signaling pathwayGO:004356840.012
multicellular organismal response to stressGO:003355510.012
intrinsic apoptotic signaling pathwayGO:00971931270.012
nucleoside monophosphate catabolic processGO:00091251590.012
organic acid transportGO:0015849650.012
myoblast fusionGO:000752010.012
cyclic purine nucleotide metabolic processGO:0052652600.012
protein localization to membraneGO:00726571600.012
positive regulation of cell developmentGO:0010720920.012
generation of neuronsGO:00486991520.012
positive regulation of intracellular transportGO:00323881040.012
adenylate cyclase modulating g protein coupled receptor signaling pathwayGO:0007188430.012
regulation of dna metabolic processGO:00510521530.012
response to woundingGO:00096111680.012
rna processingGO:00063962550.012
anterior posterior axis specification embryoGO:000859520.012
regenerationGO:003109940.012
regulation of nucleoside metabolic processGO:00091182090.012
negative regulation of developmental processGO:00510932470.012
circulatory system developmentGO:00723592620.012
atp catabolic processGO:00062001570.012
av node cell to bundle of his cell communicationGO:008606740.012
regulation of intracellular protein transportGO:00331571230.012
regulation of protein maturationGO:19033171500.012
peptide secretionGO:0002790510.012
regulation of purine nucleotide biosynthetic processGO:1900371500.012
regulation of multi organism processGO:00439001570.011
purine ribonucleotide biosynthetic processGO:0009152790.011
regulation of protein processingGO:00706131500.011
endocytosisGO:00068971590.011
positive regulation of purine nucleotide catabolic processGO:00331231850.011
hemopoiesisGO:00300971800.011
defense response to fungusGO:005083240.011
potassium ion transportGO:0006813620.011
spermatid developmentGO:000728640.011
regulation of wnt signaling pathwayGO:00301111230.011
cell fate determinationGO:000170930.011
positive regulation of nucleoside metabolic processGO:00459791860.011
regulation of muscle contractionGO:0006937450.011
regulation of excitatory postsynaptic membrane potentialGO:006007910.011
posttranscriptional regulation of gene expressionGO:00106082130.011
carboxylic acid transportGO:0046942630.011
regulation of actin cytoskeleton organizationGO:00329561160.011
reactive nitrogen species metabolic processGO:200105730.011
negative regulation of voltage gated calcium channel activityGO:190138640.011
protein importGO:00170381300.011
regulation of canonical wnt signaling pathwayGO:0060828880.011
monocarboxylic acid metabolic processGO:00327871850.011
peptidyl tyrosine phosphorylationGO:00181081700.011
regulation of nucleocytoplasmic transportGO:0046822980.011
regulation of neural precursor cell proliferationGO:200017740.011
lipid biosynthetic processGO:00086101770.011
serotonin transportGO:000683730.011
regulation of cyclic nucleotide biosynthetic processGO:0030802490.011
positive regulation of protein serine threonine kinase activityGO:00719021190.011
positive regulation of steroid hormone biosynthetic processGO:009003120.011
multi organism cellular processGO:00447641560.011
regulation of meiotic cell cycleGO:005144540.011
protein secretionGO:0009306980.011
cellular response to cytokine stimulusGO:00713451810.011
negative regulation of phosphorylationGO:00423261740.011
positive regulation of cell cycleGO:00457871400.011
inorganic anion transportGO:0015698600.011
single organism nuclear importGO:19025931040.011
regulation of endopeptidase activityGO:00525481700.011
positive regulation of nucleotide catabolic processGO:00308131850.011
head developmentGO:00603221080.011
central nervous system developmentGO:00074171230.011
positive regulation of cytoplasmic transportGO:1903651820.011
regulation of cell divisionGO:00513021160.011
positive regulation of cell adhesionGO:0045785840.011
exocytosisGO:0006887710.011
Mouse
negative regulation of transferase activityGO:00513481240.011
organic acid biosynthetic processGO:0016053970.011
regulation of peptidase activityGO:00525471800.011
organelle fissionGO:00482851490.011
negative regulation of growthGO:0045926970.011
negative regulation of immune system processGO:00026831360.011
immune effector processGO:00022521590.011
regulation of epithelial cell proliferationGO:00506781130.011
regulation of gtp catabolic processGO:00331241800.011
response to hypoxiaGO:0001666960.011
cellular response to organic cyclic compoundGO:00714071270.010
hair follicle morphogenesisGO:003106920.010
dna repairGO:00062811980.010
positive regulation of reactive oxygen species metabolic processGO:2000379240.010
glutamate receptor signaling pathwayGO:0007215230.010
coagulationGO:0050817780.010
behaviorGO:00076101120.010
organic hydroxy compound metabolic processGO:19016151470.010
interspecies interaction between organismsGO:00444191560.010

OTOF disease predictions

DiseaseDO term IDSizeProbabilityFunc Analog Org
eye and adnexa diseaseDOID:14921500.033
nervous system diseaseDOID:8634310.033
eye diseaseDOID:56141490.033
retinal diseaseDOID:56791180.033
sensory system diseaseDOID:00501552030.033
night blindnessDOID:8499100.033
disease of metabolismDOID:00146672950.024
musculoskeletal system diseaseDOID:172230.021
Human
retinal degenerationDOID:8466890.018
central nervous system diseaseDOID:3311860.016
disease of cellular proliferationDOID:145661740.012
cancerDOID:1621670.012
inherited metabolic disorderDOID:6552420.012
organ system cancerDOID:00506861640.012
neurodegenerative diseaseDOID:12891020.011
connective tissue diseaseDOID:651090.010
bone diseaseDOID:0080001880.010