Homo sapiens

145 known processes

LCK

lymphocyte-specific protein tyrosine kinase

(Aliases: pp58lck,LSK,YT16,p56lck)

LCK biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
positive regulation of alpha beta t cell proliferationGO:004664151.000
t cell activationGO:0042110991.000
leukocyte activationGO:00453211641.000
t cell receptor signaling pathwayGO:0050852211.000
Human Mouse
positive regulation of leukocyte activationGO:0002696801.000
immune response regulating signaling pathwayGO:0002764971.000
Human Mouse
cell activationGO:00017752131.000
regulation of leukocyte activationGO:00026941151.000
regulation of antigen receptor mediated signaling pathwayGO:0050854101.000
Mouse
negative regulation of mitochondrial depolarizationGO:005190221.000
Human
immune response regulating cell surface receptor signaling pathwayGO:0002768511.000
Human Mouse
enzyme linked receptor protein signaling pathwayGO:00071673031.000
Human
t cell selectionGO:004505840.999
positive thymic t cell selectionGO:004505910.999
regulation of t cell receptor signaling pathwayGO:005085670.999
Mouse
regulation of cell activationGO:00508651250.999
regulation of calcium mediated signalingGO:0050848170.999
positive regulation of t cell activationGO:0050870540.999
amine metabolic processGO:0009308440.999
mast cell activation involved in immune responseGO:000227940.999
single organismal cell cell adhesionGO:00163371480.999
Human Fly
regulation of alpha beta t cell differentiationGO:004663750.999
regulation of cell migrationGO:00303342890.998
Human
positive regulation of calcium mediated signalingGO:0050850100.998
single organism cell adhesionGO:00986021790.998
Human Fly
positive regulation of immune responseGO:00507781590.998
Human Mouse
regulation of leukocyte proliferationGO:0070663670.998
negative regulation of peptidyl tyrosine phosphorylationGO:0050732200.998
Human
negative regulation of phosphate metabolic processGO:00459362670.998
Human
thymic t cell selectionGO:004506120.998
lymphocyte differentiationGO:0030098350.998
antigen receptor mediated signaling pathwayGO:0050851380.998
Human Mouse
positive regulation of cell activationGO:0050867810.998
t cell differentiationGO:0030217290.998
calcium mediated signalingGO:0019722440.997
immune responseGO:00069553070.997
Human Mouse
hematopoietic or lymphoid organ developmentGO:00485341860.997
positive regulation of lymphocyte activationGO:0051251730.997
biological adhesionGO:00226103310.997
Human Fly
regulation of cellular ketone metabolic processGO:0010565500.996
transmembrane receptor protein tyrosine kinase signaling pathwayGO:00071691810.996
regulation of t cell activationGO:0050863770.996
peptidyl tyrosine modificationGO:00182121700.996
immune response activating cell surface receptor signaling pathwayGO:0002429450.996
Human Mouse
alpha beta t cell differentiationGO:004663270.996
positive regulation of cellular amino acid metabolic processGO:004576430.995
negative regulation of catalytic activityGO:00430863350.995
Human
positive regulation of t cell proliferationGO:0042102330.995
regulation of epithelial cell migrationGO:0010632930.995
Human
positive regulation of lymphocyte proliferationGO:0050671460.994
positive regulation of immune system processGO:00026842830.994
mononuclear cell proliferationGO:0032943710.994
immune response activating signal transductionGO:0002757900.993
Human Mouse
regulation of blood coagulationGO:0030193420.993
lymphocyte proliferationGO:0046651700.993
positive regulation of leukocyte proliferationGO:0070665480.993
regulation of lymphocyte activationGO:00512491030.992
cellular amino acid metabolic processGO:00065201160.991
regulation of mononuclear cell proliferationGO:0032944650.990
positive regulation of protein kinase b signalingGO:0051897420.989
Human
long term memoryGO:000761620.988
Fly
activation of immune responseGO:00022531140.988
Human Mouse
hemopoiesisGO:00300971800.987
positive regulation of alpha beta t cell activationGO:0046635100.985
cell developmentGO:00484683280.984
Human Fly
caveolin mediated endocytosisGO:007258440.984
Human
tissue migrationGO:00901301190.981
Human
vesicle mediated transportGO:00161923710.981
Human
dephosphorylationGO:00163112090.977
positive regulation of alpha beta t cell differentiationGO:004663840.977
protein autophosphorylationGO:00467771230.974
Human Mouse Rat Worm
positive regulation of cell migration involved in sprouting angiogenesisGO:009005030.974
establishment or maintenance of epithelial cell apical basal polarityGO:004519710.972
leukocyte differentiationGO:0002521980.971
lymphocyte activationGO:00466491330.971
regulation of cellular amino acid metabolic processGO:000652160.970
integrin mediated signaling pathwayGO:0007229320.964
Human
immune system developmentGO:00025201950.961
leukocyte apoptotic processGO:0071887310.960
positive regulation of cytokine biosynthetic processGO:0042108250.956
leukocyte migrationGO:00509001070.954
cellular amine metabolic processGO:0044106410.953
neuron differentiationGO:00301821380.953
Human Fly
negative regulation of protein phosphorylationGO:00019331400.952
Human
cellular response to growth factor stimulusGO:00713631970.951
Human
positive regulation of cytokine mediated signaling pathwayGO:0001961120.950
Human
cytokine productionGO:00018162470.949
Human
regulation of peptidase activityGO:00525471800.948
regulation of cell adhesionGO:00301551660.946
Human
ameboidal type cell migrationGO:00016671350.946
Human
cell projection organizationGO:00300302520.942
Human Fly
regulation of mast cell activation involved in immune responseGO:003300630.942
positive regulation of cell motilityGO:20001471770.938
negative regulation of kinase activityGO:00336731060.930
Human
regulation of peptidyl tyrosine phosphorylationGO:00507301080.926
Human Mouse
regulation of leukocyte apoptotic processGO:2000106250.922
peptidyl tyrosine phosphorylationGO:00181081700.921
regulation of protein kinase activityGO:00458592890.920
Human Fly
defense responseGO:00069523150.915
Human
positive regulation of cytokine productionGO:00018191670.914
Human
negative regulation of cellular amino acid metabolic processGO:004576320.909
positive regulation of phosphatidylinositol 3 kinase signalingGO:0014068280.909
Human
divalent inorganic cation homeostasisGO:00725071360.907
positive regulation of cell migrationGO:00303351720.906
response to biotic stimulusGO:00096072760.903
epithelial cell migrationGO:00106311190.902
Human
peptidyl tyrosine dephosphorylationGO:0035335360.902
negative regulation of protein homooligomerizationGO:003246340.898
Human
regulation of myeloid leukocyte mediated immunityGO:000288640.892
regulation of alpha beta t cell activationGO:0046634130.888
positive regulation of interleukin 4 productionGO:003275330.885
neuron projection developmentGO:00311751060.885
Human Fly
zinc ion homeostasisGO:0055069120.881
regulation of cell motilityGO:20001452990.876
Human
regulation of cell differentiationGO:00455953930.875
Human Mouse
neurogenesisGO:00220081690.874
Human Fly
second messenger mediated signalingGO:0019932780.869
adaptive immune responseGO:0002250490.868
endodermal cell fate specificationGO:000171440.862
Worm
regulation of vesicle mediated transportGO:00606271300.862
Human
negative regulation of cellular amine metabolic processGO:003323930.858
regulation of ion homeostasisGO:2000021730.858
Human Mouse
positive regulation of response to interferon gammaGO:006033220.857
Human
negative regulation of t cell receptor signaling pathwayGO:005086040.850
regulation of locomotionGO:00400123290.839
Human
leukocyte chemotaxisGO:0030595760.831
negative regulation of protein modification processGO:00314002000.826
Human
cytoplasmic transportGO:00164823790.825
Human Mouse
negative regulation of proteolysisGO:00458611320.823
Human
t cell proliferationGO:0042098450.823
cell morphogenesisGO:00009022960.822
Human Fly
regulation of protein serine threonine kinase activityGO:00719001790.820
mapk cascadeGO:00001652880.819
cell adhesionGO:00071553250.813
Human Fly
regulation of cell cell adhesionGO:0022407570.811
Human
sprouting angiogenesisGO:0002040290.809
cellular ketone metabolic processGO:0042180800.809
regulation of cell migration involved in sprouting angiogenesisGO:009004990.796
establishment or maintenance of cell polarityGO:0007163310.794
Worm
interferon gamma productionGO:0032609390.792
Human
positive regulation of cell differentiationGO:00455972110.785
Human Mouse
cell projection morphogenesisGO:00488581290.785
Fly
cell fate commitment involved in formation of primary germ layerGO:006079560.784
Worm
regulation of t cell differentiationGO:0045580190.780
Mouse
positive regulation of neurogenesisGO:0050769490.778
Human
leukocyte proliferationGO:0070661740.777
negative regulation of phosphorus metabolic processGO:00105632670.769
Human
negative regulation of apoptotic processGO:00430663160.767
Human
negative regulation of programmed cell deathGO:00430693210.766
Human
granulocyte chemotaxisGO:0071621370.765
endodermal cell fate commitmentGO:000171140.758
Worm
taxisGO:00423301570.752
Fly
oogenesisGO:004847720.751
Fly
generation of neuronsGO:00486991520.746
Human Fly
regulation of lymphocyte proliferationGO:0050670640.739
phagocytosis recognitionGO:000691030.733
positive regulation of neuron differentiationGO:0045666400.733
Human
cytokine mediated signaling pathwayGO:00192211090.729
Human
wound healingGO:00420601150.727
positive regulation of exocytosisGO:0045921350.721
positive regulation of cellular amine metabolic processGO:003324070.720
single organism cellular localizationGO:19025803320.718
Worm
actin polymerization or depolymerizationGO:0008154560.713
Fly
negative regulation of protein metabolic processGO:00512483910.709
Human
positive regulation of protein kinase activityGO:00458601900.708
Fly
positive regulation of protein phosphorylationGO:00019343130.704
Mouse Fly
positive regulation of nervous system developmentGO:0051962540.696
Human
transmembrane receptor protein serine threonine kinase signaling pathwayGO:00071781250.695
Human
regulation of neuron projection developmentGO:0010975570.684
Human
negative regulation of map kinase activityGO:0043407270.680
negative regulation of leukocyte apoptotic processGO:2000107160.680
actin filament polymerizationGO:0030041450.674
cellular component morphogenesisGO:00329893140.673
Human Fly
cytokine biosynthetic processGO:0042089370.666
cell type specific apoptotic processGO:00972851250.657
regulation of stress activated protein kinase signaling cascadeGO:0070302850.657
regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domainsGO:0002822290.656
negative regulation of cellular protein metabolic processGO:00322693530.653
Human
negative regulation of protein tyrosine kinase activityGO:0061099130.651
Human
associative learningGO:000830610.643
Fly
regulation of response to external stimulusGO:00321012220.637
positive regulation of locomotionGO:00400171860.636
negative regulation of protein kinase activityGO:0006469980.632
Human
regulation of immune responseGO:00507762010.627
Human Mouse
endodermal cell differentiationGO:0035987310.625
Worm
nervous system developmentGO:00073992930.623
Human Fly
transforming growth factor beta receptor signaling pathwayGO:0007179760.616
Human
cellular zinc ion homeostasisGO:0006882100.604
regulation of erk1 and erk2 cascadeGO:0070372990.603
regulation of cell projection organizationGO:00313441070.599
Human
tumor necrosis factor superfamily cytokine productionGO:0071706450.598
positive regulation of interferon gamma productionGO:0032729260.595
Human
regulation of interleukin 4 productionGO:003267370.583
positive regulation of epithelial cell migrationGO:0010634550.578
multicellular organismal agingGO:001025930.576
regulation of response to cytokine stimulusGO:0060759460.568
Human
positive regulation of interferon gamma mediated signaling pathwayGO:006033520.568
Human
formation of primary germ layerGO:0001704420.568
Worm
negative regulation of cysteine type endopeptidase activity involved in apoptotic processGO:0043154460.566
Human
myeloid leukocyte activationGO:0002274340.559
behaviorGO:00076101120.558
Fly
positive regulation of antigen receptor mediated signaling pathwayGO:005085730.556
regulation of extrinsic apoptotic signaling pathwayGO:2001236850.556
Human
positive regulation of cellular component movementGO:00512721810.555
response to cytokineGO:00340972320.554
Human
positive regulation of programmed cell deathGO:00430682490.544
regulation of leukocyte mediated immunityGO:0002703380.541
positive t cell selectionGO:004336820.537
negative regulation of cell deathGO:00605483450.537
Human
regulation of adaptive immune responseGO:0002819330.521
response to radiationGO:00093141510.517
memoryGO:000761330.513
Fly
positive regulation of blood vessel endothelial cell migrationGO:0043536160.498
regulation of cellular amine metabolic processGO:0033238110.497
positive regulation of mononuclear cell proliferationGO:0032946470.496
negative regulation of protein serine threonine kinase activityGO:0071901570.484
cell migration involved in sprouting angiogenesisGO:0002042190.482
regulation of endothelial cell migrationGO:0010594670.472
cation homeostasisGO:00550801890.469
negative regulation of phosphorylationGO:00423261740.467
Human
negative regulation of protein processingGO:00109551420.461
Human
blood vessel endothelial cell migrationGO:0043534420.457
alpha beta t cell proliferationGO:004663350.455
actin filament organizationGO:00070151280.455
Human Fly
stress activated protein kinase signaling cascadeGO:0031098940.450
regulation of cysteine type endopeptidase activityGO:20001161270.440
negative regulation of smoothened signaling pathwayGO:004587930.439
positive regulation of cellular component organizationGO:00511303760.437
Human
positive regulation of developmental processGO:00510943140.436
Human Mouse
negative regulation of protein oligomerizationGO:003246080.426
Human
regulation of receptor mediated endocytosisGO:0048259320.424
Human
regulation of cellular component biogenesisGO:00440872810.418
Human Fly
serotonin transportGO:000683730.416
positive regulation of t cell receptor signaling pathwayGO:005086220.406
platelet activationGO:0030168440.406
establishment or maintenance of bipolar cell polarityGO:006124520.402
negative regulation of endopeptidase activityGO:0010951840.396
Human
early endosome to late endosome transportGO:0045022210.392
Human
positive regulation of cell projection organizationGO:0031346640.387
Human
mast cell degranulationGO:004330340.383
regulation of response to woundingGO:19030341010.382
protein processingGO:00164852260.382
regulation of intrinsic apoptotic signaling pathwayGO:2001242720.382
intrinsic apoptotic signaling pathwayGO:00971931270.379
reactive nitrogen species metabolic processGO:200105730.372
neuron projection morphogenesisGO:0048812500.371
Fly
regulation of sequence specific dna binding transcription factor activityGO:00510902110.368
Human
metal ion homeostasisGO:00550651690.365
endosomal transportGO:00161971290.365
Human
actin filament bundle organizationGO:0061572540.365
Human Fly
granulocyte migrationGO:0097530400.362
defense response to other organismGO:00985421290.361
cell part morphogenesisGO:00329901370.358
Fly
cellular response to oxygen containing compoundGO:19017012760.358
Human
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domainsGO:0002460400.352
positive regulation of cell proliferationGO:00082843010.349
Human
regulation of cellular component movementGO:00512703340.348
Human
regulation of defense responseGO:00313471540.348
Human
cell cell junction assemblyGO:0007043250.348
Fly
anatomical structure formation involved in morphogenesisGO:00486462840.347
Worm Fly
negative regulation of cell adhesionGO:0007162640.344
regulation of lymphocyte apoptotic processGO:0070228150.341
lymphocyte apoptotic processGO:0070227200.337
endoderm formationGO:0001706330.336
Worm
negative regulation of multicellular organismal processGO:00512413170.330
Fly
epithelium migrationGO:00901321190.327
Human
negative regulation of mapk cascadeGO:0043409560.326
regulation of growthGO:00400081650.323
Fly
digestive tract morphogenesisGO:0048546560.322
Worm
neutrophil migrationGO:1990266250.321
positive regulation of cell deathGO:00109422630.320
cellular response to interleukin 15GO:007135060.320
regulation of membrane depolarizationGO:0003254190.318
Human
apoptotic signaling pathwayGO:00971902680.315
regulation of mast cell activationGO:003300350.314
regulation of reactive oxygen species metabolic processGO:2000377410.314
positive regulation of interleukin 2 biosynthetic processGO:004508650.312
t cell differentiation in thymusGO:003307740.312
positive regulation of reactive oxygen species metabolic processGO:2000379240.307
positive regulation of myeloid leukocyte mediated immunityGO:000288810.305
regulation of cytokine productionGO:00018172320.294
Human
monoamine transportGO:0015844100.290
organelle localizationGO:0051640840.288
Worm
regulation of proteolysisGO:00301622930.287
response to transforming growth factor betaGO:0071559940.286
Human
activation of cysteine type endopeptidase activity involved in apoptotic processGO:0006919490.281
epithelial cell cell adhesionGO:009013670.275
Fly
negative regulation of hydrolase activityGO:00513461820.275
Human
neuromuscular junction developmentGO:000752830.273
Fly
regulation of t cell proliferationGO:0042129420.272
positive regulation of apoptotic processGO:00430652460.270
regulation of anoikisGO:2000209190.268
Human
regulation of endopeptidase activityGO:00525481700.267
cell morphogenesis involved in neuron differentiationGO:0048667440.265
Fly
negative regulation of intracellular signal transductionGO:19025321830.263
Human
positive regulation of cytokine secretionGO:0050715420.258
positive regulation of leukocyte degranulationGO:004330230.253
cellular transition metal ion homeostasisGO:0046916210.251
cellular response to acid chemicalGO:0071229440.250
Human
negative regulation of calcium mediated signalingGO:005084940.248
protein dephosphorylationGO:0006470810.245
alpha beta t cell activationGO:0046631150.241
establishment of protein localization to plasma membraneGO:0090002680.240
negative regulation of protein maturationGO:19033181420.238
Human
negative regulation of adaptive immune responseGO:000282090.234
positive regulation of cysteine type endopeptidase activityGO:2001056790.232
regulation of caveolin mediated endocytosisGO:200128620.228
Human
regulation of mitochondrial membrane potentialGO:0051881230.228
Human
cell chemotaxisGO:00603261120.221
positive regulation of cytoskeleton organizationGO:0051495830.220
Human
interleukin 2 biosynthetic processGO:004209470.219
receptor mediated endocytosisGO:0006898840.214
Human
regulation of actin filament based processGO:00329701410.214
Human Fly
regulation of protein oligomerizationGO:0032459260.213
Human
protein localization to membraneGO:00726571600.212
regulation of anatomical structure sizeGO:00900661010.210
Fly
activation of cysteine type endopeptidase activityGO:0097202570.210
regulation of neurogenesisGO:0050767820.201
Human
cellular response to lipidGO:00713961270.201
Human
cellular response to dna damage stimulusGO:00069743790.199
notch signaling pathwayGO:0007219310.197
response to bacteriumGO:00096171440.197
regulation of actin filament polymerizationGO:0030833500.195
mitotic cell cycleGO:00002783260.191
Worm
protein acylationGO:00435431380.189
regulation of blood vessel endothelial cell migrationGO:0043535300.189
response to drugGO:0042493810.184
regulation of interleukin 2 productionGO:0032663190.182
response to uvGO:0009411730.181
negative regulation of anoikisGO:2000811150.181
Human
regulation of map kinase activityGO:00434051080.180
stress activated mapk cascadeGO:0051403930.179
regulation of cellular response to stressGO:00801352440.173
regulation of interferon gamma productionGO:0032649360.173
Human
leukocyte mediated cytotoxicityGO:0001909270.172
negative regulation of phosphatase activityGO:0010923610.170
receptor internalizationGO:0031623430.170
membrane organizationGO:00610242920.168
regulation of protein maturationGO:19033171500.167
Human
negative regulation of peptidase activityGO:0010466910.165
Human
cellular response to cytokine stimulusGO:00713451810.161
Human
positive regulation of phosphorylationGO:00423273940.159
Human Mouse Fly
lysosome localizationGO:0032418100.159
regulation of neuron differentiationGO:0045664700.159
Human
cell growthGO:00160491600.157
response to light stimulusGO:0009416870.156
coagulationGO:0050817780.156
gland developmentGO:0048732480.153
Fly
tor signalingGO:0031929390.152
positive regulation of cell developmentGO:0010720920.152
Human
muscle structure developmentGO:0061061980.152
response to acid chemicalGO:0001101660.149
Human
leukocyte mediated immunityGO:0002443590.149
response to fungusGO:000962040.149
kidney developmentGO:0001822530.147
single organism membrane organizationGO:00448022680.145
negative regulation of intrinsic apoptotic signaling pathwayGO:2001243400.144
Human
detection of mechanical stimulusGO:005098240.143
actin filament based processGO:00300292240.143
Human Fly
maintenance of cell polarityGO:003001120.142
growthGO:00400072020.141
Fly
regulation of mast cell degranulationGO:004330430.140
positive regulation of apoptotic signaling pathwayGO:2001235700.140
regulation of innate immune responseGO:0045088970.136
Human
mitotic cell cycle processGO:19030472860.134
Worm
protein localization to organelleGO:00333652800.134
defense response to bacteriumGO:0042742630.134
negative regulation of transferase activityGO:00513481240.133
Human
negative regulation of cysteine type endopeptidase activityGO:2000117480.132
Human
cytokine metabolic processGO:0042107380.131
chemotaxisGO:00069351570.131
Fly
negative regulation of developmental processGO:00510932470.130
Fly
cell morphogenesis involved in differentiationGO:00009041440.129
Fly
regulation of secretion by cellGO:19035301770.128
Human
neuron developmentGO:00486661130.128
Human Fly
negative regulation of apoptotic signaling pathwayGO:2001234970.126
Human
lipid metabolic processGO:00066293810.124
Human
protein maturationGO:00516042330.122
positive regulation of endothelial cell migrationGO:0010595390.122
regulation of phagocytosisGO:0050764210.121
Human
cell junction organizationGO:0034330790.121
Fly
regulation of lipid metabolic processGO:0019216960.120
Human
osteoclast developmentGO:003603520.120
axon developmentGO:0061564340.119
Fly
endomembrane system organizationGO:00102561960.118
negative regulation of transcription from rna polymerase ii promoterGO:00001222810.117
actomyosin structure organizationGO:0031032590.117
Human Fly
chemical homeostasisGO:00488783060.115
cellular response to endogenous stimulusGO:00714953360.115
Human
regulation of hemostasisGO:1900046420.110
protein homooligomerizationGO:00512601000.110
Human
regulation of actin polymerization or depolymerizationGO:0008064560.109
Fly
motor neuron axon guidanceGO:000804520.109
response to organonitrogen compoundGO:00102431560.105
regulation of protein localizationGO:00328802960.105
natural killer cell proliferationGO:000178740.104
regulation of membrane potentialGO:0042391950.103
Human
positive regulation of dna metabolic processGO:0051054730.103
protein localization to plasma membraneGO:0072659930.103
regulation of regulated secretory pathwayGO:1903305100.101
tyrosine phosphorylation of stat proteinGO:0007260330.100
Human Mouse
positive regulation of cysteine type endopeptidase activity involved in apoptotic processGO:0043280690.099
protein localization to nucleusGO:00345041360.098
establishment of spindle orientationGO:005129490.097
Worm
signal transduction in response to dna damageGO:0042770570.097
plasma membrane organizationGO:00070091150.097
heart processGO:0003015620.096
t cell costimulationGO:003129570.096
positive regulation of catabolic processGO:00098963100.096
divalent metal ion transportGO:00708381520.095
Mouse
cell cell signalingGO:00072671550.095
Human Fly
i kappab kinase nf kappab signalingGO:00072491660.094
negative regulation of cellular component organizationGO:00511292350.092
Human Fly
regulation of transferase activityGO:00513383550.092
Human Fly
reactive oxygen species metabolic processGO:0072593750.091
digestive tract developmentGO:0048565750.090
Worm
exocrine system developmentGO:003527270.090
Fly
protein kinase b signalingGO:0043491690.089
Human
determination of adult lifespanGO:000834020.089
regulation of actin filament lengthGO:0030832560.087
Fly
endocytosisGO:00068971590.087
Human
membrane protein ectodomain proteolysisGO:0006509330.087
regulation of neutrophil activationGO:190256310.086
cellular response to abiotic stimulusGO:00712141170.086
cellular response to transforming growth factor beta stimulusGO:0071560940.086
Human
plasma membrane raft assemblyGO:004485440.085
positive regulation of neuron projection developmentGO:0010976340.085
Human
positive regulation of insulin secretionGO:0032024100.084
Human
ribonucleoprotein complex biogenesisGO:00226131160.084
regulation of kinase activityGO:00435493140.084
Human Fly
regulation of cell shapeGO:0008360480.082
Human
brain developmentGO:0007420970.081
Fly
smoothened signaling pathwayGO:0007224140.080
gamma delta t cell activationGO:004662930.080
Mouse
positive regulation of defense responseGO:0031349870.076
Human
positive regulation of actin cytoskeleton reorganizationGO:200025190.075
Human
regulation of hormone levelsGO:00108171250.075
Human
positive regulation of adaptive immune responseGO:0002821210.073
cellular response to nitrogen compoundGO:19016991440.072
positive regulation of interleukin 2 productionGO:0032743110.072
protein catabolic processGO:00301633250.071
regulation of actin cytoskeleton reorganizationGO:2000249120.071
Human
negative regulation of growthGO:0045926970.070
Fly
organelle assemblyGO:00709251760.070
Human
regulation of body fluid levelsGO:0050878990.069
response to growth factorGO:00708482050.069
Human
regulation of acute inflammatory response to antigenic stimulusGO:000286410.067
oocyte differentiationGO:000999420.066
microtubule based processGO:00070172100.066
Worm
glucose metabolic processGO:0006006450.065
cellular ion homeostasisGO:00068731680.065
negative regulation of protein complex assemblyGO:0031333430.064
Human
positive regulation of transportGO:00510503360.064
Human
positive regulation of endopeptidase activityGO:0010950840.063
regulation of intracellular transportGO:00323861950.062
Human
positive regulation of peptidyl tyrosine phosphorylationGO:0050731850.062
Mouse
positive regulation of immune effector processGO:0002699400.060
regulation of coagulationGO:0050818440.060
stress fiber assemblyGO:0043149400.060
Human
regulation of cell morphogenesisGO:00226041530.059
Human
response to abiotic stimulusGO:00096283360.059
Rat
macrophage activation involved in immune responseGO:000228110.059
regulation of cyclin dependent protein serine threonine kinase activityGO:0000079360.059
regulation of protein secretionGO:0050708860.058
negative regulation of homeostatic processGO:0032845590.058
Mouse
cellular response to hormone stimulusGO:00328701250.057
mast cell mediated immunityGO:000244850.057
regulation of cytokine secretionGO:0050707570.057
positive regulation of cell adhesionGO:0045785840.057
posttranscriptional regulation of gene expressionGO:00106082130.057
positive regulation of membrane protein ectodomain proteolysisGO:0051044130.057
positive regulation of response to cytokine stimulusGO:0060760130.056
Human
regulation of protein processingGO:00706131500.055
Human
regulation of establishment of protein localizationGO:00702012420.055
phagocytosisGO:0006909420.055
Human
innate immune responseGO:00450871780.054
Human
negative regulation of locomotionGO:00400131180.054
b cell receptor signaling pathwayGO:0050853180.054
Human Mouse
system processGO:00030083490.054
Rat Fly
response to woundingGO:00096111680.054
response to hormoneGO:00097251750.054
negative regulation of extrinsic apoptotic signaling pathwayGO:2001237520.053
Human
signal transduction by phosphorylationGO:00230142970.053
positive regulation of tolerance inductionGO:000264520.053

LCK disease predictions

DiseaseDO term IDSizeProbabilityFunc Analog Org
immune system diseaseDOID:29141550.784
Human
hypersensitivity reaction diseaseDOID:0060056250.218
disease of metabolismDOID:00146672950.155
carbohydrate metabolism diseaseDOID:0050013320.155
acquired metabolic diseaseDOID:0060158580.155
hematopoietic system diseaseDOID:741000.121
Human
systemic lupus erythematosusDOID:9074120.060
hypersensitivity reaction type ii diseaseDOID:417190.060
connective tissue diseaseDOID:651090.060
musculoskeletal system diseaseDOID:172230.060
lupus erythematosusDOID:8857120.060