Homo sapiens

0 known processes

SMPDL3A

sphingomyelin phosphodiesterase, acid-like 3A

(Aliases: ASM3A,ASML3a,FLJ20177,yR36GH4.1)

SMPDL3A biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
cellular amino acid metabolic processGO:00065201160.064
post embryonic developmentGO:000979120.060
cellular amine metabolic processGO:0044106410.053
cellular ketone metabolic processGO:0042180800.053
cellular lipid metabolic processGO:00442553030.053
Human
amine metabolic processGO:0009308440.052
determination of adult lifespanGO:000834020.052
lipid metabolic processGO:00066293810.050
Human
multicellular organismal agingGO:001025930.047
regulation of cellular amino acid metabolic processGO:000652160.043
regulation of cellular ketone metabolic processGO:0010565500.041
regulation of cellular amine metabolic processGO:0033238110.038
organophosphate catabolic processGO:00464344300.036
negative regulation of protein metabolic processGO:00512483910.036
Human
positive regulation of catabolic processGO:00098963100.035
purine ribonucleoside metabolic processGO:00461284370.035
positive regulation of cellular amino acid metabolic processGO:004576430.035
positive regulation of cellular amine metabolic processGO:003324070.034
cellular macromolecule catabolic processGO:00442653800.033
nucleoside triphosphate metabolic processGO:00091414220.033
oxidation reduction processGO:00551143960.033
glycosyl compound catabolic processGO:19016584130.033
positive regulation of transportGO:00510503360.033
response to oxygen containing compoundGO:19017003690.033
purine nucleoside triphosphate metabolic processGO:00091444120.032
single organism membrane organizationGO:00448022680.032
monocarboxylic acid metabolic processGO:00327871850.031
purine containing compound catabolic processGO:00725234110.031
positive regulation of cellular catabolic processGO:00313312840.031
immune responseGO:00069553070.030
locomotory behaviorGO:000762610.030
ribonucleoside triphosphate catabolic processGO:00092033910.030
nucleotide catabolic processGO:00091664080.030
purine nucleoside catabolic processGO:00061523980.030
negative regulation of cellular protein metabolic processGO:00322693530.030
Human
purine ribonucleoside triphosphate metabolic processGO:00092054110.029
defense responseGO:00069523150.029
nucleoside catabolic processGO:00091644080.029
ras protein signal transductionGO:0007265730.029
membrane organizationGO:00610242920.029
ribonucleoside triphosphate metabolic processGO:00091994120.029
small gtpase mediated signal transductionGO:0007264780.029
transmembrane transportGO:00550853990.029
cytoplasmic transportGO:00164823790.029
purine nucleotide catabolic processGO:00061954050.029
nucleoside phosphate catabolic processGO:19012924120.028
purine ribonucleotide catabolic processGO:00091544040.028
vesicle mediated transportGO:00161923710.028
ribonucleotide catabolic processGO:00092614050.028
anion transportGO:00068201610.028
nucleoside triphosphate catabolic processGO:00091433940.028
purine ribonucleoside catabolic processGO:00461303980.028
ribonucleoside catabolic processGO:00424544060.027
purine ribonucleoside triphosphate catabolic processGO:00092073910.027
segmentationGO:003528240.027
cation transportGO:00068123310.027
positive regulation of immune system processGO:00026842830.027
apoptotic signaling pathwayGO:00971902680.026
innate immune responseGO:00450871780.026
small molecule biosynthetic processGO:00442831570.026
single organism cellular localizationGO:19025803320.026
positive regulation of cellular component organizationGO:00511303760.026
system processGO:00030083490.025
negative regulation of catalytic activityGO:00430863350.025
Human
protein maturationGO:00516042330.025
actin filament based processGO:00300292240.025
regulation of transferase activityGO:00513383550.025
Human
ion homeostasisGO:00508012300.025
metal ion transportGO:00300012720.025
regulation of kinase activityGO:00435493140.025
Human
positive regulation of phosphorylationGO:00423273940.025
purine nucleoside triphosphate catabolic processGO:00091463920.025
positive regulation of hydrolase activityGO:00513453310.025
regulation of cell cycleGO:00517263930.025
biological adhesionGO:00226103310.025
protein catabolic processGO:00301633250.025
chemical homeostasisGO:00488783060.024
regulation of protein localizationGO:00328802960.024
oogenesisGO:004847720.024
regulation of cellular component movementGO:00512703340.024
cellular protein catabolic processGO:00442572610.024
carbohydrate metabolic processGO:00059752070.024
protein modification by small protein conjugationGO:00324463420.024
female gamete generationGO:000729220.024
ion transmembrane transportGO:00342203380.024
organic anion transportGO:00157111030.024
endomembrane system organizationGO:00102561960.023
regulation of purine nucleotide metabolic processGO:19005422640.023
organic hydroxy compound metabolic processGO:19016151470.023
response to abiotic stimulusGO:00096283360.023
negative regulation of phosphate metabolic processGO:00459362670.023
Human
regulation of proteolysisGO:00301622930.023
positive regulation of nucleotide metabolic processGO:00459812300.022
organonitrogen compound biosynthetic processGO:19015662000.022
Human
lipid biosynthetic processGO:00086101770.022
Human
regenerationGO:003109940.022
regulation of nucleotide metabolic processGO:00061402690.022
negative regulation of cell deathGO:00605483450.022
negative regulation of cellular component organizationGO:00511292350.022
regulation of establishment of protein localizationGO:00702012420.022
cellular component morphogenesisGO:00329893140.022
positive regulation of purine nucleotide metabolic processGO:19005442270.022
protein ubiquitinationGO:00165673140.022
cell adhesionGO:00071553250.021
carbohydrate derivative biosynthetic processGO:19011372070.021
regulation of protein kinase activityGO:00458592890.021
Human
secretion by cellGO:00329402260.021
alcohol metabolic processGO:00060661140.021
regulation of response to external stimulusGO:00321012220.021
negative regulation of phosphorus metabolic processGO:00105632670.021
Human
cell morphogenesisGO:00009022960.021
proteolysis involved in cellular protein catabolic processGO:00516032440.021
cation transmembrane transportGO:00986552380.021
rho protein signal transductionGO:0007266260.021
cellular macromolecular complex assemblyGO:00346223240.021
guanosine containing compound metabolic processGO:19010682440.021
regulation of cytokine productionGO:00018172320.021
signal transduction by phosphorylationGO:00230142970.021
Human
cellular response to dna damage stimulusGO:00069743790.021
regulation of anatomical structure morphogenesisGO:00226032860.021
inorganic ion transmembrane transportGO:00986602310.021
regulation of cell differentiationGO:00455953930.021
protein processingGO:00164852260.021
negative regulation of apoptotic processGO:00430663160.021
cellular response to oxygen containing compoundGO:19017012760.020
mapk cascadeGO:00001652880.020
Human
regulation of cell motilityGO:20001452990.020
regulation of secretionGO:00510461940.020
protein localization to organelleGO:00333652800.020
neuromuscular junction developmentGO:000752830.020
regulation of immune responseGO:00507762010.020
sulfur compound metabolic processGO:00067901010.020
intracellular protein transportGO:00068862700.020
negative regulation of multicellular organismal processGO:00512413170.020
memoryGO:000761330.020
negative regulation of cell proliferationGO:00082852280.019
regulation of mapk cascadeGO:00434082620.019
Human
mitotic cell cycleGO:00002783260.019
negative regulation of programmed cell deathGO:00430693210.019
adult locomotory behaviorGO:000834410.019
regulation of cellular response to stressGO:00801352440.019
fatty acid metabolic processGO:00066311150.019
cytokine productionGO:00018162470.019
blastoderm segmentationGO:000735020.019
regulation of locomotionGO:00400123290.019
response to cytokineGO:00340972320.019
positive regulation of transferase activityGO:00513472270.019
negative regulation of protein modification processGO:00314002000.019
Human
gtp metabolic processGO:00460392390.019
organic acid biosynthetic processGO:0016053970.018
cellular response to endogenous stimulusGO:00714953360.018
positive regulation of cell proliferationGO:00082843010.018
secretionGO:00469032540.018
guanosine containing compound catabolic processGO:19010692390.018
single organism carbohydrate metabolic processGO:00447231930.018
nitrogen compound transportGO:00717051910.018
regulation of cell migrationGO:00303342890.018
cell projection organizationGO:00300302520.018
modification dependent protein catabolic processGO:00199412090.018
hindbrain developmentGO:003090230.018
glycoprotein metabolic processGO:00091001100.018
nervous system developmentGO:00073992930.018
cellular homeostasisGO:00197251960.018
dephosphorylationGO:00163112090.018
Human
regulation of cellular component biogenesisGO:00440872810.018
posttranscriptional regulation of gene expressionGO:00106082130.018
regulation of apoptotic signaling pathwayGO:20012331750.018
gtp catabolic processGO:00061842370.018
response to organic cyclic compoundGO:00140702040.018
response to biotic stimulusGO:00096072760.018
inorganic cation transmembrane transportGO:00986621940.018
enzyme linked receptor protein signaling pathwayGO:00071673030.018
positive regulation of nucleoside metabolic processGO:00459791860.018
negative regulation of hydrolase activityGO:00513461820.018
negative regulation of cellular amine metabolic processGO:003323930.018
cation homeostasisGO:00550801890.017
positive regulation of protein phosphorylationGO:00019343130.017
peripheral nervous system developmentGO:000742220.017
response to external biotic stimulusGO:00432072610.017
carboxylic acid biosynthetic processGO:0046394970.017
regulation of cell cycle processGO:00105642660.017
response to lipidGO:00339932060.017
neurological system processGO:00508771630.017
negative regulation of cellular amino acid metabolic processGO:004576320.017
protein localization to membraneGO:00726571600.017
neurotransmitter secretionGO:000726940.017
maintenance of locationGO:00512351120.017
regulation of purine nucleotide catabolic processGO:00331212050.017
positive regulation of nucleotide catabolic processGO:00308131850.017
regulation of protein transportGO:00512232130.017
regulation of nucleotide catabolic processGO:00308112050.017
response to other organismGO:00517072610.017
positive regulation of cell deathGO:00109422630.017
regulation of intracellular transportGO:00323861950.017
modification dependent macromolecule catabolic processGO:00436322120.017
ubiquitin dependent protein catabolic processGO:00065112060.017
anterior posterior axis specificationGO:000994820.017
negative regulation of transportGO:00510511760.016
organophosphate biosynthetic processGO:00904071630.016
cell developmentGO:00484683280.016
cofactor metabolic processGO:0051186870.016
positive regulation of programmed cell deathGO:00430682490.016
cell activationGO:00017752130.016
regulation of secretion by cellGO:19035301770.016
negative regulation of intracellular signal transductionGO:19025321830.016
Human
cellular chemical homeostasisGO:00550821800.016
negative regulation of developmental processGO:00510932470.016
positive regulation of apoptotic processGO:00430652460.016
negative regulation of cell cycleGO:00457861930.016
mitotic cell cycle processGO:19030472860.016
positive regulation of kinase activityGO:00336742040.016
nerve developmentGO:002167540.016
regulation of protein maturationGO:19033171500.016
regulation of ion transportGO:00432691890.016
glycerolipid metabolic processGO:00464861070.016
reactive oxygen species metabolic processGO:0072593750.016
immune effector processGO:00022521590.016
cardiac muscle cell contractionGO:008600340.015
spermatid differentiationGO:004851540.015
anatomical structure formation involved in morphogenesisGO:00486462840.015
organ formationGO:004864530.015
regulation of cytoskeleton organizationGO:00514931770.015
regulation of defense responseGO:00313471540.015
oocyte differentiationGO:000999420.015
negative regulation of phosphorylationGO:00423261740.015
Human
cellular response to cytokine stimulusGO:00713451810.015
inner ear morphogenesisGO:004247240.015
positive regulation of gtpase activityGO:00435471660.015
lipid transportGO:0006869900.015
reactive oxygen species biosynthetic processGO:190340940.015
positive regulation of organelle organizationGO:00106381950.015
positive regulation of purine nucleotide catabolic processGO:00331231850.015
protein oligomerizationGO:00512591730.015
metal ion homeostasisGO:00550651690.015
regulation of gtpase activityGO:00430871800.015
cellular cation homeostasisGO:00300031630.015
regulation of nucleoside metabolic processGO:00091182090.015
regulation of endopeptidase activityGO:00525481700.015
regulation of protein processingGO:00706131500.015
compound eye developmentGO:004874910.015
cellular ion homeostasisGO:00068731680.015
positive regulation of developmental processGO:00510943140.015
response to hormoneGO:00097251750.015
oocyte developmentGO:004859910.015
regulation of gtp catabolic processGO:00331241800.014
reactive nitrogen species metabolic processGO:200105730.014
proteasomal protein catabolic processGO:00104981760.014
lipid catabolic processGO:0016042840.014
rhythmic behaviorGO:000762220.014
regulation of protein catabolic processGO:00421761550.014
microtubule based processGO:00070172100.014
proteasome mediated ubiquitin dependent protein catabolic processGO:00431611560.014
tripartite regional subdivisionGO:000735120.014
coenzyme metabolic processGO:0006732650.014
cellular protein complex assemblyGO:00436231880.014
actin cytoskeleton organizationGO:00300362070.014
regulation of synaptic plasticityGO:004816730.014
negative regulation of protein maturationGO:19033181420.014
morphogenesis of embryonic epitheliumGO:001633140.014
associative learningGO:000830610.014
purine ribonucleoside monophosphate metabolic processGO:00091671860.014
ribonucleoside monophosphate metabolic processGO:00091611870.014
positive regulation of gtp catabolic processGO:00331261660.014
establishment of protein localization to membraneGO:00901501210.014
tissue regenerationGO:004224630.014
spermatid developmentGO:000728640.014
rab protein signal transductionGO:003248240.014
circulatory system developmentGO:00723592620.014
regulation of peptidase activityGO:00525471800.014
regulation of ras protein signal transductionGO:00465781550.014
anterior posterior axis specification embryoGO:000859520.014
purine nucleoside monophosphate metabolic processGO:00091261860.014
response to fungusGO:000962040.014
positive regulation of mapk cascadeGO:00434101900.014
positive regulation of protein kinase activityGO:00458601900.014
thymus developmentGO:004853830.014
nucleoside monophosphate metabolic processGO:00091231910.013
positive regulation of cell differentiationGO:00455972110.013
sensory perception of smellGO:000760820.013
regulation of vesicle mediated transportGO:00606271300.013
lipid localizationGO:00108761060.013
actin mediated cell contractionGO:0070252120.013
circadian behaviorGO:004851220.013
positive regulation of cell motilityGO:20001471770.013
positive regulation of cellular component movementGO:00512721810.013
regulation of small gtpase mediated signal transductionGO:00510561560.013
cell growthGO:00160491600.013
release of cytoplasmic sequestered nf kappabGO:000858840.013
protein targetingGO:00066051870.013
steroid metabolic processGO:0008202940.013
rna processingGO:00063962550.013
embryonic epithelial tube formationGO:000183840.013
regulation of reactive oxygen species biosynthetic processGO:190342630.013
regulation of sequence specific dna binding transcription factor activityGO:00510902110.013
endosomal transportGO:00161971290.013
leukocyte activationGO:00453211640.013
cellular metal ion homeostasisGO:00068751460.013
response to oxidative stressGO:00069791210.013
rna interferenceGO:001624640.013
cell cycle phase transitionGO:00447701730.013
syncytium formation by plasma membrane fusionGO:000076820.013
sequestering of metal ionGO:0051238240.013
negative regulation of protein processingGO:00109551420.013
positive regulation of proteolysisGO:00458621420.013
positive regulation of synaptic transmissionGO:005080640.013
regulation of multi organism processGO:00439001570.013
mitochondrion organizationGO:00070051560.013
divalent metal ion transportGO:00708381520.013
negative regulation of transcription from rna polymerase ii promoterGO:00001222810.013
positive regulation of cellular component biogenesisGO:00440891580.013
startle responseGO:000196430.013
growthGO:00400072020.013
cardiovascular system developmentGO:00723582620.012
divalent inorganic cation transportGO:00725111580.012
long term memoryGO:000761620.012
plasma membrane organizationGO:00070091150.012
regulation of cytoplasmic transportGO:19036491490.012
motor neuron axon guidanceGO:000804520.012
regulation of neural precursor cell proliferationGO:200017740.012
atp metabolic processGO:00460341760.012
regulation of hormone levelsGO:00108171250.012
carboxylic acid transportGO:0046942630.012
visual behaviorGO:000763220.012
neurogenesisGO:00220081690.012
regulation of ras gtpase activityGO:00323181280.012
actin filament based movementGO:0030048170.012
positive regulation of locomotionGO:00400171860.012
cell fate determinationGO:000170930.012
limbic system developmentGO:002176130.012
establishment of protein localization to organelleGO:00725941720.012
regulation of reactive oxygen species metabolic processGO:2000377410.012
monocarboxylic acid biosynthetic processGO:0072330670.012
response to nitrogen compoundGO:19016981840.012
regulation of growthGO:00400081650.012
cellular response to lipidGO:00713961270.012
matingGO:000761810.012
regulation of meiotic cell cycleGO:005144540.012
metencephalon developmentGO:002203720.012
protein homooligomerizationGO:00512601000.012
cell divisionGO:00513011680.012
positive regulation of cell migrationGO:00303351720.012
regulation of cell morphogenesisGO:00226041530.012
wnt signaling pathwayGO:00160551560.012
response to woundingGO:00096111680.012
positive regulation of secretionGO:00510471160.012
epithelium developmentGO:00604292270.012
glycoprotein biosynthetic processGO:0009101910.012
positive regulation of ras gtpase activityGO:00323201170.012
cell substrate adhesionGO:00315891320.012
immune system developmentGO:00025201950.012
endocytosisGO:00068971590.012
response to inorganic substanceGO:00100351270.012
negative regulation of immune system processGO:00026831360.012
positive regulation of immune responseGO:00507781590.012
organelle assemblyGO:00709251760.012
epithelial cell proliferationGO:00506731280.012
nucleoside monophosphate catabolic processGO:00091251590.012
small molecule catabolic processGO:0044282920.012
morphogenesis of a polarized epitheliumGO:000173830.012
neuroblast proliferationGO:000740540.012
hemopoiesisGO:00300971800.012
nuclear transportGO:00511691790.012
regulation of cell adhesionGO:00301551660.012
negative regulation of proteolysisGO:00458611320.012
phospholipid metabolic processGO:0006644990.012
protein localization to plasma membraneGO:0072659930.012
cell projection assemblyGO:00300311260.012
single organism cell adhesionGO:00986021790.012
positive regulation of protein transportGO:00512221350.011
interspecies interaction between organismsGO:00444191560.011
divalent inorganic cation homeostasisGO:00725071360.011
cellular lipid catabolic processGO:0044242650.011
photoreceptor cell differentiationGO:004653020.011
response to growth factorGO:00708482050.011
mitotic cell cycle phase transitionGO:00447721620.011
purine ribonucleoside monophosphate catabolic processGO:00091691580.011
organic acid transportGO:0015849650.011
regulation of protein serine threonine kinase activityGO:00719001790.011
Human
cellular response to growth factor stimulusGO:00713631970.011
response to axon injuryGO:004867810.011
symbiosis encompassing mutualism through parasitismGO:00444031560.011
meiosis iGO:000712740.011
sex determinationGO:000753030.011
blood vessel morphogenesisGO:00485141620.011
negative regulation of protein phosphorylationGO:00019331400.011
Human
cerebellum developmentGO:002154920.011
calcium ion transportGO:00068161470.011
meiotic chromosome segregationGO:004513240.011
ribonucleoside monophosphate catabolic processGO:00091581580.011
positive regulation of reactive oxygen species metabolic processGO:2000379240.011
cranial nerve developmentGO:002154540.011
response to virusGO:00096151260.011
i kappab kinase nf kappab signalingGO:00072491660.011
vasculature developmentGO:00019441810.011
histone modificationGO:00165702510.011
serotonin transportGO:000683730.011
monovalent inorganic cation transportGO:00156721280.011
regulation of cysteine type endopeptidase activityGO:20001161270.011
peptidyl tyrosine phosphorylationGO:00181081700.011
cell part morphogenesisGO:00329901370.011
positive regulation of cytokine productionGO:00018191670.011
negative regulation of transferase activityGO:00513481240.011
Human
g protein coupled receptor signaling pathwayGO:00071862070.011
covalent chromatin modificationGO:00165692540.011
regulation of protein complex assemblyGO:00432541470.011
regulation of homeostatic processGO:00328441210.011
hematopoietic or lymphoid organ developmentGO:00485341860.011
negative regulation of organelle organizationGO:00106391260.011
stem cell divisionGO:001714520.011
response to radiationGO:00093141510.011
t cell differentiation in thymusGO:003307740.011
activation of immune responseGO:00022531140.011
regulation of i kappab kinase nf kappab signalingGO:00431221620.011
sequestering of calcium ionGO:0051208170.011
regulation of metal ion transportGO:00109591200.011
regulation of dna metabolic processGO:00510521530.011
autophagyGO:0006914880.011
positive regulation of secretion by cellGO:19035321080.011
chromatin modificationGO:00165682980.011
regulation of leukocyte activationGO:00026941150.011
dna repairGO:00062811980.011
myoblast fusionGO:000752010.011
positive regulation of reactive oxygen species biosynthetic processGO:190342820.011
nucleocytoplasmic transportGO:00069131760.011
cdc42 protein signal transductionGO:003248840.011
regulation of membrane potentialGO:0042391950.011
regulation of cell growthGO:00015581350.011
response to organonitrogen compoundGO:00102431560.011
microtubule cytoskeleton organizationGO:00002261760.011
regulation of cell activationGO:00508651250.011
cellular response to glucocorticoid stimulusGO:007138540.011
neural crest cell developmentGO:001403230.011
embryonic camera type eye developmentGO:003107620.011
neural tube formationGO:000184130.011
regulation of neurotransmitter secretionGO:004692830.011
regulation of mitotic cell cycleGO:00073461890.011
regulation of protein stabilityGO:0031647870.011
generation of neuronsGO:00486991520.011
negative regulation of catabolic processGO:00098951040.010
protein importGO:00170381300.010
single organismal cell cell adhesionGO:00163371480.010
sensory perception of painGO:001923340.010
extrinsic apoptotic signaling pathwayGO:00971911190.010
regulation of actin filament based processGO:00329701410.010
lymphocyte activationGO:00466491330.010
regulation of wnt signaling pathwayGO:00301111230.010
peptidyl tyrosine modificationGO:00182121700.010
developmental programmed cell deathGO:001062330.010
response to bacteriumGO:00096171440.010
cellular response to organic cyclic compoundGO:00714071270.010
tube closureGO:006060630.010
cellular response to external stimulusGO:00714961110.010
calcium ion homeostasisGO:00550741220.010
establishment of planar polarityGO:000173630.010
blood vessel developmentGO:00015681720.010
cellular response to oxidative stressGO:0034599850.010
spinal cord developmentGO:002151040.010
central nervous system developmentGO:00074171230.010
regulation of cell developmentGO:00602841610.010
visual learningGO:000854210.010
chromatin organizationGO:00063253510.010
regulation of cysteine type endopeptidase activity involved in apoptotic processGO:00432811160.010
regulation of innate immune responseGO:0045088970.010
purine nucleoside monophosphate catabolic processGO:00091281580.010
nucleotide biosynthetic processGO:00091651090.010
atp catabolic processGO:00062001570.010
canonical wnt signaling pathwayGO:00600701160.010
regulation of meiosisGO:004002030.010

SMPDL3A disease predictions

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of metabolismDOID:00146672950.059
Human
inherited metabolic disorderDOID:6552420.051
Human
nervous system diseaseDOID:8634310.027
sensory system diseaseDOID:00501552030.027
musculoskeletal system diseaseDOID:172230.022
disease of cellular proliferationDOID:145661740.021
cancerDOID:1621670.021
eye and adnexa diseaseDOID:14921500.021
eye diseaseDOID:56141490.021
retinal diseaseDOID:56791180.019
central nervous system diseaseDOID:3311860.019
organ system cancerDOID:00506861640.016
retinal degenerationDOID:8466890.015
connective tissue diseaseDOID:651090.014
cardiovascular system diseaseDOID:12871060.014
immune system diseaseDOID:29141550.014
Human
muscle tissue diseaseDOID:661130.014
muscular diseaseDOID:00800001140.014
amino acid metabolic disorderDOID:9252500.013
myopathyDOID:4231040.013
bone diseaseDOID:0080001880.012
neurodegenerative diseaseDOID:12891020.012
brain diseaseDOID:936730.012
acquired metabolic diseaseDOID:0060158580.012
hematopoietic system diseaseDOID:741000.010