Homo sapiens

56 known processes

DOT1L

DOT1-like, histone H3 methyltransferase (S. cerevisiae)

(Aliases: KMT4,DOT1,KIAA1814,DKFZp586P1823)

DOT1L biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
covalent chromatin modificationGO:00165692540.976
histone modificationGO:00165702510.928
protein acylationGO:00435431380.905
histone acetylationGO:0016573930.861
internal peptidyl lysine acetylationGO:0018393970.779
peptidyl lysine modificationGO:00182051440.771
histone h4 k12 acetylationGO:004398360.751
histone h3 acetylationGO:0043966450.698
regulation of cell cycle processGO:00105642660.692
negative regulation of cell cycle processGO:00109481210.567
protein acetylationGO:00064731160.564
mitotic cell cycleGO:00002783260.542
histone h4 acetylationGO:0043967470.530
histone h4 k8 acetylationGO:0043982150.505
internal protein amino acid acetylationGO:00064751010.501
regulation of mitotic cell cycleGO:00073461890.483
mitotic cell cycle phase transitionGO:00447721620.469
negative regulation of cell cycleGO:00457861930.462
chromatin modificationGO:00165682980.434
regulation of wnt signaling pathway planar cell polarity pathwayGO:200009520.427
regulation of cell cycleGO:00517263930.402
morphogenesis of a polarized epitheliumGO:000173830.358
negative regulation of mitotic cell cycleGO:00459301020.308
cellular macromolecule catabolic processGO:00442653800.285
chromatin organizationGO:00063253510.275
mitotic cell cycle processGO:19030472860.271
nucleotide excision repairGO:0006289310.251
post embryonic developmentGO:000979120.247
regulation of cell cycle phase transitionGO:19019871260.243
negative regulation of cell cycle phase transitionGO:1901988890.240
regulation of mitotic cell cycle phase transitionGO:19019901180.236
regulation of cellular amine metabolic processGO:0033238110.234
negative regulation of mitotic cell cycle phase transitionGO:1901991850.228
regulation of proteasomal protein catabolic processGO:0061136870.224
cell cycle phase transitionGO:00447701730.212
chromosome separationGO:0051304230.210
histone h4 k5 acetylationGO:0043981150.197
ubiquitin dependent protein catabolic processGO:00065112060.195
anaphase promoting complex dependent proteasomal ubiquitin dependent protein catabolic processGO:0031145250.193
cellular amine metabolic processGO:0044106410.188
cellular response to dna damage stimulusGO:00069743790.183
chromatin assemblyGO:0031497610.178
regulation of proteasomal ubiquitin dependent protein catabolic processGO:0032434710.178
negative regulation of proteasomal protein catabolic processGO:1901799320.177
amine metabolic processGO:0009308440.172
negative regulation of cellular catabolic processGO:0031330830.171
chromatin assembly or disassemblyGO:0006333780.171
dna replication independent nucleosome organizationGO:0034724270.166
nucleosome assemblyGO:0006334500.159
negative regulation of cell deathGO:00605483450.157
posttranscriptional regulation of gene expressionGO:00106082130.157
nucleosome organizationGO:0034728660.156
mitotic sister chromatid segregationGO:0000070530.152
cellular ketone metabolic processGO:0042180800.151
cellular macromolecular complex assemblyGO:00346223240.151
regulation of mitosisGO:0007088630.144
regulation of mitotic metaphase anaphase transitionGO:0030071260.143
negative regulation of catabolic processGO:00098951040.142
negative regulation of protein processingGO:00109551420.138
regulation of cellular protein catabolic processGO:1903362960.125
protein maturationGO:00516042330.122
regulation of chromosome segregationGO:0051983440.122
dna conformation changeGO:00711031130.121
sister chromatid segregationGO:0000819540.119
determination of adult lifespanGO:000834020.118
proteasome mediated ubiquitin dependent protein catabolic processGO:00431611560.112
dna replication dependent nucleosome assemblyGO:0006335320.112
anatomical structure formation involved in morphogenesisGO:00486462840.112
gene silencingGO:0016458490.112
epithelium developmentGO:00604292270.111
mitotic sister chromatid separationGO:0051306180.111
negative regulation of wnt signaling pathwayGO:0030178690.111
cell divisionGO:00513011680.109
rna interferenceGO:001624640.107
cellular amino acid metabolic processGO:00065201160.106
negative regulation of chromosome organizationGO:2001251480.104
regulation of mitotic sister chromatid separationGO:0010965270.101
establishment of tissue polarityGO:000716430.097
segmentationGO:003528240.095
regulation of cell cycle g1 s phase transitionGO:1902806420.094
protein dna complex assemblyGO:0065004640.093
negative regulation of protein maturationGO:19033181420.093
dna packagingGO:0006323770.090
establishment of planar polarityGO:000173630.090
regulation of cell growthGO:00015581350.090
cell cycle checkpointGO:00000751170.088
regulation of cellular amino acid metabolic processGO:000652160.088
cellular protein catabolic processGO:00442572610.088
dna repairGO:00062811980.086
mitotic nuclear divisionGO:00070671190.086
negative regulation of protein metabolic processGO:00512483910.083
regulation of protein maturationGO:19033171500.082
spindle assembly checkpointGO:0071173170.081
regulation of protein processingGO:00706131500.080
regulation of sister chromatid segregationGO:0033045270.079
negative regulation of cellular component organizationGO:00511292350.076
negative regulation of chromosome segregationGO:0051985180.075
modification dependent macromolecule catabolic processGO:00436322120.075
regulation of cell divisionGO:00513021160.075
regulation of gene expression epigeneticGO:0040029730.074
positive regulation of mapk cascadeGO:00434101900.074
negative regulation of programmed cell deathGO:00430693210.072
mitotic spindle checkpointGO:0071174180.071
reproductive processGO:00224141060.071
carbohydrate metabolic processGO:00059752070.071
single organism reproductive processGO:0044702980.071
regulation of canonical wnt signaling pathwayGO:0060828880.071
multicellular organismal agingGO:001025930.070
protein dna complex subunit organizationGO:0071824800.069
dna replication independent nucleosome assemblyGO:0006336270.068
regulation of metaphase anaphase transition of cell cycleGO:1902099260.068
organelle fissionGO:00482851490.065
proteolysis involved in cellular protein catabolic processGO:00516032440.065
negative regulation of cellular protein metabolic processGO:00322693530.064
modification dependent protein catabolic processGO:00199412090.064
regulation of mitotic sister chromatid segregationGO:0033047270.062
locomotory behaviorGO:000762610.062
regulation of protein catabolic processGO:00421761550.062
proteasomal protein catabolic processGO:00104981760.061
protein processingGO:00164852260.061
protein catabolic processGO:00301633250.061
chromosome segregationGO:00070591140.061
positive regulation of non canonical wnt signaling pathwayGO:200005230.060
negative regulation of cell cycle g1 s phase transitionGO:1902807290.060
negative regulation of mitotic metaphase anaphase transitionGO:0045841170.060
positive regulation of phosphorylationGO:00423273940.060
metaphase anaphase transition of mitotic cell cycleGO:0007091210.059
negative regulation of protein catabolic processGO:0042177590.059
dna replication dependent nucleosome organizationGO:0034723320.059
organophosphate catabolic processGO:00464344300.059
wnt signaling pathway planar cell polarity pathwayGO:006007150.059
purine ribonucleoside catabolic processGO:00461303980.058
growthGO:00400072020.058
nuclear divisionGO:00002801280.058
mapk cascadeGO:00001652880.058
regulation of proteolysis involved in cellular protein catabolic processGO:1903050910.056
cell cycle g1 s phase transitionGO:0044843800.055
regulation of g1 s transition of mitotic cell cycleGO:2000045400.055
regulation of wnt signaling pathwayGO:00301111230.054
negative regulation of canonical wnt signaling pathwayGO:0090090550.054
membrane organizationGO:00610242920.053
negative regulation of proteolysis involved in cellular protein catabolic processGO:1903051350.051
regulation of protein serine threonine kinase activityGO:00719001790.050
oogenesisGO:004847720.050
regulation of proteolysisGO:00301622930.049
nucleoside phosphate catabolic processGO:19012924120.049
purine ribonucleoside triphosphate metabolic processGO:00092054110.049
embryo developmentGO:00097901230.049
ribonucleotide catabolic processGO:00092614050.048
peptidyl lysine acetylationGO:00183941010.048
positive regulation of cellular amino acid metabolic processGO:004576430.048
wnt signaling pathwayGO:00160551560.047
small gtpase mediated signal transductionGO:0007264780.047
positive regulation of cellular amine metabolic processGO:003324070.046
positive regulation of cell proliferationGO:00082843010.046
negative regulation of apoptotic processGO:00430663160.044
system processGO:00030083490.044
cellular lipid metabolic processGO:00442553030.044
cell growthGO:00160491600.043
female gamete generationGO:000729220.043
spindle checkpointGO:0031577260.043
negative regulation of proteolysisGO:00458611320.042
regulation of protein kinase activityGO:00458592890.042
nucleotide catabolic processGO:00091664080.042
negative regulation of cellular protein catabolic processGO:1903363380.041
tissue morphogenesisGO:0048729960.041
vesicle mediated transportGO:00161923710.041
regulation of establishment of planar polarityGO:009017550.041
ribonucleoside triphosphate metabolic processGO:00091994120.041
regulation of cell differentiationGO:00455953930.041
signal transduction by phosphorylationGO:00230142970.040
ribonucleoside catabolic processGO:00424544060.039
nucleoside triphosphate metabolic processGO:00091414220.039
defense responseGO:00069523150.039
negative regulation of g1 s transition of mitotic cell cycleGO:2000134290.039
regulation of locomotionGO:00400123290.039
regulation of purine nucleotide metabolic processGO:19005422640.038
purine containing compound catabolic processGO:00725234110.038
canonical wnt signaling pathwayGO:00600701160.037
purine nucleoside triphosphate metabolic processGO:00091444120.037
posttranscriptional gene silencing by rnaGO:0035194250.037
glycosyl compound catabolic processGO:19016584130.037
organ morphogenesisGO:00098871470.037
carbohydrate derivative biosynthetic processGO:19011372070.036
regulation of growthGO:00400081650.036
positive regulation of transferase activityGO:00513472270.035
neuromuscular junction developmentGO:000752830.035
rho protein signal transductionGO:0007266260.035
developmental process involved in reproductionGO:0003006660.034
peptidyl serine phosphorylationGO:00181051010.034
cell developmentGO:00484683280.034
regulation of chromosome organizationGO:00330441030.034
peptidyl serine modificationGO:00182091060.034
regulation of nuclear divisionGO:0051783650.034
negative regulation of cell proliferationGO:00082852280.033
negative regulation of proteasomal ubiquitin dependent protein catabolic processGO:0032435300.033
regulation of cell motilityGO:20001452990.033
positive regulation of developmental processGO:00510943140.033
lipid metabolic processGO:00066293810.032
posttranscriptional gene silencingGO:0016441250.032
cytoplasmic transportGO:00164823790.032
positive regulation of protein kinase activityGO:00458601900.031
single organism cellular localizationGO:19025803320.031
protein localization to organelleGO:00333652800.031
single organism carbohydrate metabolic processGO:00447231930.031
histone methylationGO:0016571600.031
regulation of gene silencingGO:0060968240.031
organelle assemblyGO:00709251760.030
purine nucleotide catabolic processGO:00061954050.030
negative regulation of mitotic sister chromatid separationGO:2000816170.030
mitotic cell cycle checkpointGO:0007093680.030
purine nucleoside triphosphate catabolic processGO:00091463920.030
purine ribonucleoside triphosphate catabolic processGO:00092073910.030
microtubule based processGO:00070172100.029
positive regulation of wnt signaling pathwayGO:0030177540.029
nervous system developmentGO:00073992930.029
immune responseGO:00069553070.029
ras protein signal transductionGO:0007265730.029
blastoderm segmentationGO:000735020.028
negative regulation of sister chromatid segregationGO:0033046170.028
response to abiotic stimulusGO:00096283360.028
positive regulation of purine nucleotide metabolic processGO:19005442270.028
regulation of kinase activityGO:00435493140.028
response to radiationGO:00093141510.027
reproductive structure developmentGO:0048608550.027
cardiovascular system developmentGO:00723582620.027
positive regulation of catabolic processGO:00098963100.027
negative regulation of metaphase anaphase transition of cell cycleGO:1902100170.026
regulation of ras protein signal transductionGO:00465781550.026
regulation of mapk cascadeGO:00434082620.026
macromolecule methylationGO:0043414970.026
chemical homeostasisGO:00488783060.026
regulation of non canonical wnt signaling pathwayGO:200005040.025
reproductionGO:0000003630.025
positive regulation of protein phosphorylationGO:00019343130.025
response to cytokineGO:00340972320.025
atp metabolic processGO:00460341760.025
cellular chemical homeostasisGO:00550821800.025
protein ubiquitinationGO:00165673140.025
intrinsic apoptotic signaling pathwayGO:00971931270.024
regulation of peptidyl tyrosine phosphorylationGO:00507301080.024
purine ribonucleoside metabolic processGO:00461284370.024
positive regulation of gtpase activityGO:00435471660.024
negative regulation of organelle organizationGO:00106391260.024
apoptotic signaling pathwayGO:00971902680.024
glycosylationGO:0070085710.024
establishment of protein localization to organelleGO:00725941720.024
positive regulation of synaptic transmissionGO:005080640.024
negative regulation of transcription from rna polymerase ii promoterGO:00001222810.024
nucleoside triphosphate catabolic processGO:00091433940.024
positive regulation of protein serine threonine kinase activityGO:00719021190.024
positive regulation of cell growthGO:0030307480.024
positive regulation of map kinase activityGO:0043406800.023
cell fate determinationGO:000170930.023
memoryGO:000761330.023
nucleoside catabolic processGO:00091644080.023
positive regulation of wnt signaling pathway planar cell polarity pathwayGO:200009620.023
negative regulation of mitosisGO:0045839240.022
glycoprotein metabolic processGO:00091001100.022
purine nucleoside monophosphate metabolic processGO:00091261860.022
ribonucleoside monophosphate metabolic processGO:00091611870.022
regulation of organ morphogenesisGO:2000027240.022
regulation of nucleotide metabolic processGO:00061402690.022
negative regulation of phosphate metabolic processGO:00459362670.022
positive regulation of hydrolase activityGO:00513453310.022
mitotic spindle assembly checkpointGO:0007094140.022
regulation of cellular response to stressGO:00801352440.022
positive regulation of immune system processGO:00026842830.022
negative regulation of cellular amine metabolic processGO:003323930.021
striated muscle myosin thick filament assemblyGO:007168820.021
immune system developmentGO:00025201950.021
organonitrogen compound biosynthetic processGO:19015662000.021
morphogenesis of an epitheliumGO:0002009600.021
positive regulation of cell migrationGO:00303351720.021
methylationGO:00322591060.021
regulation of response to dna damage stimulusGO:2001020940.021
regulation of transferase activityGO:00513383550.021
compound eye developmentGO:004874910.020
guanosine containing compound metabolic processGO:19010682440.020
oxidation reduction processGO:00551143960.020
negative regulation of cell divisionGO:0051782310.020
g1 s transition of mitotic cell cycleGO:0000082780.020
glycoprotein biosynthetic processGO:0009101910.020
extrinsic apoptotic signaling pathwayGO:00971911190.020
cell cycle arrestGO:0007050710.020
positive regulation of nucleotide metabolic processGO:00459812300.020
positive regulation of kinase activityGO:00336742040.020
mrna metabolic processGO:00160711750.020
nitrogen compound transportGO:00717051910.020
regulation of cellular component biogenesisGO:00440872810.020
ameboidal type cell migrationGO:00016671350.020
tissue migrationGO:00901301190.020
regulation of immune responseGO:00507762010.020
spermatid developmentGO:000728640.019
circulatory system developmentGO:00723592620.019
regulation of dna metabolic processGO:00510521530.019
peripheral nervous system developmentGO:000742220.019
anterior posterior axis specificationGO:000994820.019
oocyte developmentGO:004859910.019
spermatid differentiationGO:004851540.019
gtp catabolic processGO:00061842370.019
cell type specific apoptotic processGO:00972851250.019
peptidyl tyrosine phosphorylationGO:00181081700.019
regulation of chromatin organizationGO:1902275560.019
protein methylationGO:0006479740.019
hematopoietic or lymphoid organ developmentGO:00485341860.019
ribonucleoside triphosphate catabolic processGO:00092033910.019
regulation of sequence specific dna binding transcription factor activityGO:00510902110.018
tube developmentGO:00352951250.018
cellular homeostasisGO:00197251960.018
regulation of cell activationGO:00508651250.018
regulation of cell migrationGO:00303342890.018
peptidyl tyrosine modificationGO:00182121700.018
leukocyte activationGO:00453211640.018
muscle tissue developmentGO:0060537620.018
purine nucleoside catabolic processGO:00061523980.018
activation of protein kinase activityGO:0032147900.017
regulation of anatomical structure morphogenesisGO:00226032860.017
single organism membrane organizationGO:00448022680.017
protein localization to membraneGO:00726571600.017
regenerationGO:003109940.017
development of primary sexual characteristicsGO:0045137350.017
purine ribonucleoside monophosphate metabolic processGO:00091671860.017
cell projection organizationGO:00300302520.017
nucleocytoplasmic transportGO:00069131760.017
negative regulation of catalytic activityGO:00430863350.017
apoptotic mitochondrial changesGO:0008637570.017
histone h3 k9 modificationGO:0061647110.017
cellular protein complex assemblyGO:00436231880.016
regulation of apoptotic signaling pathwayGO:20012331750.016
cell activationGO:00017752130.016
negative regulation of cellular amino acid metabolic processGO:004576320.016
positive regulation of dna metabolic processGO:0051054730.016
regulation of cellular component movementGO:00512703340.016
endomembrane system organizationGO:00102561960.016
alcohol metabolic processGO:00060661140.016
reactive nitrogen species metabolic processGO:200105730.016
tripartite regional subdivisionGO:000735120.016
receptor mediated endocytosisGO:0006898840.016
protein modification by small protein conjugationGO:00324463420.016
epithelial cell migrationGO:00106311190.016
regulation of synaptic plasticityGO:004816730.016
positive regulation of cell deathGO:00109422630.016
purine ribonucleotide catabolic processGO:00091544040.016
intracellular protein transportGO:00068862700.016
nucleoside monophosphate catabolic processGO:00091251590.016
myosin filament organizationGO:003103320.016
heart contractionGO:0060047620.015
epithelium migrationGO:00901321190.015
gonad developmentGO:0008406340.015
regulation of gtpase activityGO:00430871800.015
nuclear transportGO:00511691790.015
establishment of protein localization to membraneGO:00901501210.015
regulation of microtubule cytoskeleton organizationGO:0070507610.015
protein alkylationGO:0008213740.015
organophosphate biosynthetic processGO:00904071630.015
salivary gland morphogenesisGO:000743540.015
nucleus localizationGO:005164710.015
regulation of response to external stimulusGO:00321012220.015
positive regulation of nucleoside metabolic processGO:00459791860.015
cytokine productionGO:00018162470.014
regulation of secretion by cellGO:19035301770.014
associative learningGO:000830610.014
nucleoside monophosphate metabolic processGO:00091231910.014
regulation of mitochondrion organizationGO:0010821540.014
atp catabolic processGO:00062001570.014
metal ion homeostasisGO:00550651690.014
regulation of small gtpase mediated signal transductionGO:00510561560.014
regulation of secretionGO:00510461940.014
regulation of cell adhesionGO:00301551660.014
endocytosisGO:00068971590.014
regulation of purine nucleotide catabolic processGO:00331212050.014
regulation of map kinase activityGO:00434051080.014
reactive oxygen species metabolic processGO:0072593750.014
myosin filament assemblyGO:003103420.014
anterior posterior axis specification embryoGO:000859520.014
regulation of establishment of protein localizationGO:00702012420.014
protein autophosphorylationGO:00467771230.014
positive regulation of ras gtpase activityGO:00323201170.014
positive regulation of cellular catabolic processGO:00313312840.014
somitogenesisGO:000175620.014
t cell differentiation in thymusGO:003307740.014
circadian behaviorGO:004851220.014
dephosphorylationGO:00163112090.014
negative regulation of hydrolase activityGO:00513461820.013
oocyte differentiationGO:000999420.013
establishment of nucleus localizationGO:004002310.013
response to nitrogen compoundGO:19016981840.013
negative regulation of intracellular signal transductionGO:19025321830.013
cell cell signalingGO:00072671550.013
spinal cord developmentGO:002151040.013
cellular cation homeostasisGO:00300031630.013
reproductive system developmentGO:0061458560.013
negative regulation of transferase activityGO:00513481240.013
response to oxygen containing compoundGO:19017003690.013
anion transportGO:00068201610.013
sex differentiationGO:0007548450.013
positive regulation of reactive oxygen species biosynthetic processGO:190342820.013
long term memoryGO:000761620.013
reactive oxygen species biosynthetic processGO:190340940.013
cellular response to endogenous stimulusGO:00714953360.013
divalent metal ion transportGO:00708381520.013
meiotic chromosome segregationGO:004513240.013
response to axon injuryGO:004867810.013
protein localization to chromosomeGO:0034502300.013
response to lipidGO:00339932060.013
regulation of lymphocyte activationGO:00512491030.013
regulation of neurotransmitter secretionGO:004692830.013
cell part morphogenesisGO:00329901370.013
response to other organismGO:00517072610.013
lipid localizationGO:00108761060.013
protein targetingGO:00066051870.013
regulation of microtubule based processGO:0032886740.013
rna processingGO:00063962550.013
positive regulation of programmed cell deathGO:00430682490.013
positive regulation of cellular component movementGO:00512721810.013
small molecule biosynthetic processGO:00442831570.013
cell differentiation in spinal cordGO:002151510.013
cellular component morphogenesisGO:00329893140.013
mitochondrion organizationGO:00070051560.013
secretion by cellGO:00329402260.013
blood circulationGO:00080151130.013
stem cell divisionGO:001714520.012
positive regulation of cell cycleGO:00457871400.012
peptidyl lysine methylationGO:0018022370.012
neuron fate commitmentGO:004866320.012
dna replicationGO:00062601160.012
positive regulation of locomotionGO:00400171860.012
endosomal transportGO:00161971290.012
negative regulation of phosphorus metabolic processGO:00105632670.012
regulation of epithelial cell migrationGO:0010632930.012
phototransductionGO:000760230.012
actin cytoskeleton organizationGO:00300362070.012
positive regulation of apoptotic processGO:00430652460.012
engulfment of apoptotic cellGO:004365220.012
positive regulation of secretion by cellGO:19035321080.012
sex determinationGO:000753030.012
regulation of cell developmentGO:00602841610.012
myoblast fusionGO:000752010.012
motor neuron axon guidanceGO:000804520.012
immune response regulating signaling pathwayGO:0002764970.012
circulatory system processGO:00030131130.012
rna splicingGO:00083801310.012
regulation of reactive oxygen species biosynthetic processGO:190342630.012
purine ribonucleoside monophosphate catabolic processGO:00091691580.012
negative regulation of apoptotic signaling pathwayGO:2001234970.012
cdc42 protein signal transductionGO:003248840.012
neurotransmitter secretionGO:000726940.012
multi organism reproductive processGO:0044703540.012
positive regulation of nf kappab transcription factor activityGO:0051092810.012
positive regulation of proteolysisGO:00458621420.012
neuron projection regenerationGO:003110210.012
tube morphogenesisGO:0035239950.012
innate immune responseGO:00450871780.012
telomere maintenanceGO:0000723320.012
guanosine containing compound catabolic processGO:19010692390.012
rrna transcriptionGO:000930390.012
endothelial cell migrationGO:0043542860.012
activation of mapk activityGO:0000187450.011
vasculature developmentGO:00019441810.011
actin mediated cell contractionGO:0070252120.011
syncytium formation by plasma membrane fusionGO:000076820.011
sequestering of metal ionGO:0051238240.011
regulation of nucleoside metabolic processGO:00091182090.011
negative regulation of multicellular organismal processGO:00512413170.011
synaptic transmissionGO:0007268610.011
neural tube formationGO:000184130.011
regulation of protein complex assemblyGO:00432541470.011
regulation of endopeptidase activityGO:00525481700.011
cellular carbohydrate metabolic processGO:0044262840.011
response to inorganic substanceGO:00100351270.011

DOT1L disease predictions

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of cellular proliferationDOID:145661740.034
cancerDOID:1621670.027
immune system diseaseDOID:29141550.027
organ system cancerDOID:00506861640.024
muscle tissue diseaseDOID:661130.022
muscular diseaseDOID:00800001140.022
musculoskeletal system diseaseDOID:172230.022
myopathyDOID:4231040.022
disease of metabolismDOID:00146672950.022
nervous system diseaseDOID:8634310.018
sensory system diseaseDOID:00501552030.018
neuropathyDOID:870520.017
central nervous system diseaseDOID:3311860.015
cardiovascular system diseaseDOID:12871060.015
heart diseaseDOID:114680.015
neuromuscular diseaseDOID:440380.013
eye and adnexa diseaseDOID:14921500.012
eye diseaseDOID:56141490.012
brain diseaseDOID:936730.012
retinal diseaseDOID:56791180.012
integumentary system diseaseDOID:16430.012
neurodegenerative diseaseDOID:12891020.011