Homo sapiens

103 known processes

MAP2K1

mitogen-activated protein kinase kinase 1

(Aliases: MKK1,PRKMK1,MEK1,MAPKK1)

MAP2K1 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
response to nitrosative stressGO:005140941.000
ras protein signal transductionGO:0007265730.999
Rat Worm Fly
regulation of erk1 and erk2 cascadeGO:0070372990.999
Fly
erk1 and erk2 cascadeGO:00703711040.997
Fly
mapk cascadeGO:00001652880.990
photoreceptor cell differentiationGO:004653020.986
regulation of mapk cascadeGO:00434082620.984
small gtpase mediated signal transductionGO:0007264780.980
Rat Worm Fly
tor signalingGO:0031929390.974
regulation of ras protein signal transductionGO:00465781550.945
Rat Fly
regulation of map kinase activityGO:00434051080.940
positive regulation of cellular amine metabolic processGO:003324070.935
regulation of protein serine threonine kinase activityGO:00719001790.931
positive regulation of phosphorylationGO:00423273940.917
peptidyl tyrosine dephosphorylationGO:0035335360.915
Mouse
negative regulation of phosphate metabolic processGO:00459362670.903
positive regulation of erk1 and erk2 cascadeGO:0070374750.901
Fly
inactivation of mapk activityGO:000018850.888
transmembrane receptor protein tyrosine kinase signaling pathwayGO:00071691810.877
signal transduction by phosphorylationGO:00230142970.846
jun phosphorylationGO:0007258280.841
associative learningGO:000830610.839
transposition rna mediatedGO:003219700.834
Yeast
positive regulation of protein phosphorylationGO:00019343130.816
regulation of cellular amino acid metabolic processGO:000652160.801
regulation of cell cycleGO:00517263930.795
dephosphorylationGO:00163112090.792
Mouse
cellular amino acid metabolic processGO:00065201160.791
regulation of synaptic plasticityGO:004816730.788
positive regulation of cellular amino acid metabolic processGO:004576430.787
negative regulation of erk1 and erk2 cascadeGO:0070373140.782
negative regulation of catalytic activityGO:00430863350.771
cellular amine metabolic processGO:0044106410.762
macroautophagyGO:0016236390.757
negative regulation of protein serine threonine kinase activityGO:0071901570.756
regulation of kinase activityGO:00435493140.752
negative regulation of phosphorylationGO:00423261740.743
cytoplasmic transportGO:00164823790.721
Yeast
regulation of protein kinase activityGO:00458592890.717
protein dephosphorylationGO:0006470810.705
Mouse
anterior posterior axis specificationGO:000994820.683
Fly
regulation of cellular ketone metabolic processGO:0010565500.659
generation of neuronsGO:00486991520.656
Mouse Rat
neuron differentiationGO:00301821380.649
Mouse Rat
regulation of cellular response to stressGO:00801352440.644
Yeast
regulation of transferase activityGO:00513383550.608
positive regulation of transferase activityGO:00513472270.606
enzyme linked receptor protein signaling pathwayGO:00071673030.605
negative regulation of autophagyGO:0010507140.602
negative regulation of phosphorus metabolic processGO:00105632670.599
negative regulation of map kinase activityGO:0043407270.593
negative regulation of protein metabolic processGO:00512483910.570
negative regulation of apoptotic signaling pathwayGO:2001234970.567
apoptotic signaling pathwayGO:00971902680.554
negative regulation of rho gtpase activityGO:003425940.545
negative regulation of cell deathGO:00605483450.542
positive regulation of kinase activityGO:00336742040.538
negative regulation of macroautophagyGO:001624240.537
regulation of cell motilityGO:20001452990.536
Rat
negative regulation of response to extracellular stimulusGO:003210550.530
negative regulation of protein phosphorylationGO:00019331400.528
negative regulation of programmed cell deathGO:00430693210.524
response to abiotic stimulusGO:00096283360.515
Yeast
negative regulation of cell differentiationGO:00455961710.508
female gamete generationGO:000729220.503
Fly
nucleocytoplasmic transportGO:00069131760.496
Yeast
synaptic transmissionGO:0007268610.486
negative regulation of apoptotic processGO:00430663160.472
oocyte differentiationGO:000999420.466
negative regulation of cysteine type endopeptidase activity involved in apoptotic processGO:0043154460.463
activation of mapkk activityGO:0000186180.459
positive regulation of small gtpase mediated signal transductionGO:0051057120.459
Rat Fly
regulation of cellular amine metabolic processGO:0033238110.446
determination of adult lifespanGO:000834020.442
Worm
cell developmentGO:00484683280.431
Rat Fly
protein targeting to nucleusGO:00447441040.430
Yeast
regulation of neuron differentiationGO:0045664700.421
cellular response to metal ionGO:0071248430.421
establishment of protein localization to organelleGO:00725941720.416
Yeast
response to metal ionGO:0010038840.407
regulation of proteolysisGO:00301622930.403
negative regulation of mapk cascadeGO:0043409560.401
regulation of protein localizationGO:00328802960.398
nervous system developmentGO:00073992930.377
Mouse Rat
positive regulation of apoptotic processGO:00430652460.369
amine metabolic processGO:0009308440.368
response to organic cyclic compoundGO:00140702040.361
Rat
autophagyGO:0006914880.350
Yeast
mitotic cell cycleGO:00002783260.346
Rat
regulation of tor signalingGO:0032006300.343
negative regulation of extrinsic apoptotic signaling pathway via death domain receptorsGO:1902042150.343
regulation of mitotic cell cycleGO:00073461890.339
system processGO:00030083490.336
Rat
negative regulation of transportGO:00510511760.335
positive regulation of neuron differentiationGO:0045666400.331
regulation of peptidase activityGO:00525471800.331
regulation of stress activated mapk cascadeGO:0032872840.313
positive regulation of mapk cascadeGO:00434101900.307
positive regulation of developmental processGO:00510943140.301
Mouse
negative regulation of response to nutrient levelsGO:003210850.301
oocyte developmentGO:004859910.301
regulation of cell migrationGO:00303342890.297
Rat
ion transmembrane transportGO:00342203380.290
response to hormoneGO:00097251750.286
Rat
blastoderm segmentationGO:000735020.285
Fly
nucleoside catabolic processGO:00091644080.273
Rat
peptidyl serine phosphorylationGO:00181051010.272
Human
protein localization to nucleusGO:00345041360.272
Yeast
negative regulation of kinase activityGO:00336731060.270
stress activated protein kinase signaling cascadeGO:0031098940.266
regulation of apoptotic signaling pathwayGO:20012331750.264
cellular response to nutrient levelsGO:0031669690.259
peptidyl serine dephosphorylationGO:007026220.253
negative regulation of cellular protein metabolic processGO:00322693530.252
nuclear transportGO:00511691790.249
Yeast
visual learningGO:000854210.249
carbohydrate metabolic processGO:00059752070.243
regulation of translationGO:0006417890.243
negative regulation of protein kinase activityGO:0006469980.241
negative regulation of transferase activityGO:00513481240.239
cellular ketone metabolic processGO:0042180800.238
cellular response to starvationGO:0009267580.238
regulation of nervous system developmentGO:0051960880.235
tube morphogenesisGO:0035239950.232
regulation of cellular component sizeGO:0032535820.232
negative regulation of intracellular signal transductionGO:19025321830.231
positive regulation of nervous system developmentGO:0051962540.229
positive regulation of ras gtpase activityGO:00323201170.226
Rat
positive regulation of cell adhesionGO:0045785840.226
regulation of neurogenesisGO:0050767820.226
regulation of jnk cascadeGO:0046328730.225
peripheral nervous system developmentGO:000742220.225
post embryonic developmentGO:000979120.224
Worm
intracellular protein transportGO:00068862700.223
Yeast
mitotic cell cycle phase transitionGO:00447721620.222
growthGO:00400072020.221
Yeast
cation transmembrane transportGO:00986552380.221
positive regulation of meiotic cell cycleGO:005144620.217
negative regulation of response to external stimulusGO:0032102830.216
oogenesisGO:004847720.213
Fly
negative regulation of protein processingGO:00109551420.212
positive regulation of organelle organizationGO:00106381950.211
tripartite regional subdivisionGO:000735120.210
Fly
regulation of protein transportGO:00512232130.210
response to nitrogen compoundGO:19016981840.207
positive regulation of neurogenesisGO:0050769490.206
gtp catabolic processGO:00061842370.205
Rat
digestive tract morphogenesisGO:0048546560.204
regulation of locomotionGO:00400123290.204
Rat
wound healingGO:00420601150.203
anterior posterior axis specification embryoGO:000859520.202
Fly
cartilage condensationGO:000150210.202
positive regulation of protein kinase activityGO:00458601900.199
tube developmentGO:00352951250.197
response to calcium ionGO:0051592460.197
negative regulation of multicellular organismal processGO:00512413170.195
single organism nuclear importGO:19025931040.192
Yeast
protein localization to organelleGO:00333652800.192
Yeast
response to woundingGO:00096111680.192
Rat
neurogenesisGO:00220081690.192
Mouse Rat
nucleoside phosphate biosynthetic processGO:19012931090.188
response to growth factorGO:00708482050.188
regulation of cell differentiationGO:00455953930.188
Mouse
neurological system processGO:00508771630.187
positive regulation of rap gtpase activityGO:003285480.186
cellular component morphogenesisGO:00329893140.185
Rat
regulation of intracellular protein transportGO:00331571230.180
response to inorganic substanceGO:00100351270.180
cellular response to cytokine stimulusGO:00713451810.178
positive regulation of adenylate cyclase activityGO:0045762120.177
negative regulation of cell proliferationGO:00082852280.176
segmentationGO:003528240.176
Fly
negative regulation of hydrolase activityGO:00513461820.175
negative regulation of cellular component organizationGO:00511292350.170
regulation of cellular component movementGO:00512703340.168
Rat
jnk cascadeGO:0007254800.168
protein importGO:00170381300.166
Yeast
regulation of small gtpase mediated signal transductionGO:00510561560.165
Rat Fly
pattern specification processGO:0007389430.160
Fly
peptidyl serine modificationGO:00182091060.160
Human
neurotransmitter secretionGO:000726940.158
locomotory behaviorGO:000762610.158
inorganic ion transmembrane transportGO:00986602310.155
mitotic cell cycle processGO:19030472860.152
Rat
positive regulation of nf kappab transcription factor activityGO:0051092810.151
multicellular organismal agingGO:001025930.151
Worm
gastrulationGO:0007369510.149
cytokine mediated signaling pathwayGO:00192211090.149
digestive system developmentGO:0055123750.148
regulation of adenylate cyclase activityGO:0045761170.147
regulation of nucleotide metabolic processGO:00061402690.145
Rat
protein catabolic processGO:00301633250.144
Worm
regulation of ion transmembrane transporter activityGO:0032412720.143
regulation of establishment of protein localizationGO:00702012420.139
response to cytokineGO:00340972320.138
regulation of protein maturationGO:19033171500.136
negative regulation of cellular catabolic processGO:0031330830.136
negative regulation of protein modification processGO:00314002000.135
nuclear importGO:00511701060.135
Yeast
regulation of cell developmentGO:00602841610.134
embryo development ending in birth or egg hatchingGO:0009792340.133
Mouse Worm
cell cell signalingGO:00072671550.131
positive regulation of cell developmentGO:0010720920.129
chordate embryonic developmentGO:0043009340.128
Mouse
negative regulation of small gtpase mediated signal transductionGO:0051058120.127
arachidonic acid metabolic processGO:0019369140.127
negative regulation of cell migrationGO:00303361020.126
embryo developmentGO:00097901230.125
Mouse Worm Fly
regulation of response to external stimulusGO:00321012220.122
positive regulation of cellular component movementGO:00512721810.122
Rat
regulation of cysteine type endopeptidase activityGO:20001161270.122
positive regulation of cell differentiationGO:00455972110.121
Mouse
hindbrain developmentGO:003090230.121
cell projection morphogenesisGO:00488581290.120
Rat
negative regulation of cellular component movementGO:00512711060.119
covalent chromatin modificationGO:00165692540.117
cellular response to calcium ionGO:0071277190.117
negative regulation of peptidase activityGO:0010466910.116
protein autophosphorylationGO:00467771230.115
Human
response to light stimulusGO:0009416870.115
circadian behaviorGO:004851220.115
cell junction maintenanceGO:003433140.113
negative regulation of synaptic transmissionGO:005080520.111
regulation of neurotransmitter secretionGO:004692830.109
regulation of autophagyGO:0010506520.109
cell fate determinationGO:000170930.108
cognitionGO:0050890430.107
regulation of protein import into nucleusGO:0042306780.107
regulation of nucleocytoplasmic transportGO:0046822980.106
regulation of synaptic vesicle exocytosisGO:200030020.105
behavioral response to ethanolGO:004814920.105
somatic stem cell maintenanceGO:003501940.105
histone h2a s1 phosphorylationGO:004399010.104
negative regulation of catabolic processGO:00098951040.104
response to starvationGO:0042594590.103
ribonucleoside triphosphate metabolic processGO:00091994120.103
Rat
regulation of syncytium formation by plasma membrane fusionGO:006014220.103
digestive tract developmentGO:0048565750.102
regulation of stress activated protein kinase signaling cascadeGO:0070302850.102
regulation of neuronal synaptic plasticityGO:004816810.098
erbb signaling pathwayGO:0038127440.096
positive regulation of rac gtpase activityGO:0032855310.094
single organism cellular localizationGO:19025803320.094
Yeast Rat
developmental growthGO:0048589480.093
positive regulation of map kinase activityGO:0043406800.093
regulation of cellular component biogenesisGO:00440872810.093
response to radiationGO:00093141510.092
chemical homeostasisGO:00488783060.092
regulation of cytoskeleton organizationGO:00514931770.091
cell cycle arrestGO:0007050710.091
negative regulation of protein maturationGO:19033181420.090
cell fate commitmentGO:0045165270.090
positive regulation of response to woundingGO:1903036280.090
positive regulation of synaptic transmissionGO:005080640.090
positive regulation of cellular component organizationGO:00511303760.090
regulation of secretionGO:00510461940.089
cation transportGO:00068123310.089
chromatin modificationGO:00165682980.088
cell morphogenesisGO:00009022960.088
Rat
neuron projection developmentGO:00311751060.088
Rat
regulation of meiotic cell cycleGO:005144540.088
cellular response to external stimulusGO:00714961110.087
interleukin 1 mediated signaling pathwayGO:0070498120.087
transmission of nerve impulseGO:0019226110.086
response to extracellular stimulusGO:0009991850.086
peptidyl threonine phosphorylationGO:0018107410.086
epithelial tube branching involved in lung morphogenesisGO:006044140.085
secretionGO:00469032540.084
negative regulation of endopeptidase activityGO:0010951840.084
regulation of transmembrane transportGO:00347621390.084
positive regulation of wound healingGO:0090303200.083
metal ion transportGO:00300012720.082
transmembrane transportGO:00550853990.082
regulation of endopeptidase activityGO:00525481700.082
oocyte maturationGO:000155610.081
peptidyl tyrosine phosphorylationGO:00181081700.080
regulation of protein complex assemblyGO:00432541470.079
negative regulation of cell cycleGO:00457861930.079
leukocyte differentiationGO:0002521980.078
negative regulation of t cell receptor signaling pathwayGO:005086040.078
stress activated mapk cascadeGO:0051403930.077
cellular senescenceGO:0090398340.076
regulation of proteasomal protein catabolic processGO:0061136870.076
apoptotic mitochondrial changesGO:0008637570.076
mapk import into nucleusGO:000018910.075
Yeast
regulation of potassium ion transmembrane transportGO:1901379200.075
regulation of exocytosisGO:0017157460.075
oxidation reduction processGO:00551143960.075
ribonucleoside catabolic processGO:00424544060.075
Rat
regulation of intracellular transportGO:00323861950.075
negative regulation of protein dephosphorylationGO:003530830.074
regulation of wound healingGO:0061041560.073
regulation of rho protein signal transductionGO:0035023790.073
regulation of response to nutrient levelsGO:0032107220.073
response to oxygen containing compoundGO:19017003690.073
positive regulation of programmed cell deathGO:00430682490.072
cellular response to endogenous stimulusGO:00714953360.072
response to nutrient levelsGO:0031667810.072
hyperosmotic responseGO:000697240.072
Yeast
regulation of transcription by galactoseGO:000040910.071
cell growthGO:00160491600.070
Yeast
regionalizationGO:0003002290.070
Fly
ribonucleotide biosynthetic processGO:0009260810.069
cell morphogenesis involved in differentiationGO:00009041440.069
mapk export from nucleusGO:004520410.069
negative regulation of mitotic cell cycleGO:00459301020.069
behaviorGO:00076101120.069
activation of immune responseGO:00022531140.068
positive regulation of cell cycleGO:00457871400.067
response to lipidGO:00339932060.066
Rat
regulation of extrinsic apoptotic signaling pathway via death domain receptorsGO:1902041240.066
mitotic cell cycle checkpointGO:0007093680.066
regulation of cysteine type endopeptidase activity involved in apoptotic processGO:00432811160.066
positive regulation of nucleotide metabolic processGO:00459812300.065
Rat
negative regulation of extrinsic apoptotic signaling pathwayGO:2001237520.065
protein targetingGO:00066051870.065
Yeast
carbohydrate derivative biosynthetic processGO:19011372070.065
positive regulation of histone phosphorylationGO:003312930.064
response to steroid hormoneGO:0048545800.063
Rat
cellular macromolecular complex assemblyGO:00346223240.063
nucleotide biosynthetic processGO:00091651090.062
regulation of ras gtpase activityGO:00323181280.062
Rat
cyclic nucleotide metabolic processGO:0009187820.062
organelle fissionGO:00482851490.061
Rat
ubiquitin dependent protein catabolic processGO:00065112060.060
guanosine containing compound catabolic processGO:19010692390.060
Rat
cell activationGO:00017752130.060
negative regulation of locomotionGO:00400131180.060
proteasomal protein catabolic processGO:00104981760.060
positive regulation of ras protein signal transductionGO:0046579120.059
Rat Fly
regulation of response to extracellular stimulusGO:0032104220.059
circulatory system developmentGO:00723592620.059
Mouse
negative regulation of neuron deathGO:1901215320.058
cell projection organizationGO:00300302520.058
Rat
regulation of peptidyl serine phosphorylationGO:0033135500.058
regulation of ion transmembrane transportGO:00347651320.058
actin filament based processGO:00300292240.057
Yeast
cell fate specificationGO:000170880.057
skeletal muscle tissue regenerationGO:004340320.057
cellular response to organonitrogen compoundGO:00714171240.057
positive regulation of immune responseGO:00507781590.056
actin polymerization or depolymerizationGO:0008154560.056
cellular potassium ion transportGO:0071804600.056
purine ribonucleoside triphosphate metabolic processGO:00092054110.056
Rat
glycosyl compound catabolic processGO:19016584130.056
Rat
mitotic nuclear divisionGO:00070671190.056
Rat
cell part morphogenesisGO:00329901370.055
Rat
mucosal immune responseGO:0002385210.055
motor neuron axon guidanceGO:000804520.054
dna replicationGO:00062601160.054
exocytosisGO:0006887710.053
regulation of dephosphorylationGO:0035303960.053
head developmentGO:00603221080.053
cellular protein catabolic processGO:00442572610.053
histone phosphorylationGO:0016572160.052
modification dependent protein catabolic processGO:00199412090.052
response to hypoxiaGO:0001666960.052
regulation of transporter activityGO:0032409820.052
positive regulation of hydrolase activityGO:00513453310.051
Rat
histone serine phosphorylationGO:003540440.051
cellular response to inorganic substanceGO:0071241450.051
regulation of cell projection organizationGO:00313441070.050
cell aggregationGO:009874310.050
internal peptidyl lysine acetylationGO:0018393970.050
cellular response to nitrogen compoundGO:19016991440.050
peptidyl lysine modificationGO:00182051440.049
response to epidermal growth factorGO:0070849140.049
extrinsic apoptotic signaling pathway via death domain receptorsGO:0008625420.049
positive regulation of nucleotide catabolic processGO:00308131850.049
Rat
proteasome mediated ubiquitin dependent protein catabolic processGO:00431611560.049
positive regulation of cell deathGO:00109422630.049
positive regulation of cell migrationGO:00303351720.048
Rat
embryonic morphogenesisGO:0048598850.048
negative regulation of developmental processGO:00510932470.048
positive regulation of gtp catabolic processGO:00331261660.048
Rat
negative regulation of neuron differentiationGO:0045665210.047
regulation of protein processingGO:00706131500.047
divalent inorganic cation transportGO:00725111580.047
positive regulation of chromatin modificationGO:1903310300.047
visual behaviorGO:000763220.046
regulation of histone phosphorylationGO:003312750.046
cell type specific apoptotic processGO:00972851250.046
neuromuscular junction developmentGO:000752830.046
purine nucleotide biosynthetic processGO:0006164840.046
cellular ion homeostasisGO:00068731680.046
neuron deathGO:0070997650.045
immune response regulating signaling pathwayGO:0002764970.045
regulation of cytoplasmic transportGO:19036491490.045
regulation of actin cytoskeleton organizationGO:00329561160.044
cellular response to extracellular stimulusGO:0031668720.044
regulation of extrinsic apoptotic signaling pathwayGO:2001236850.044
brain developmentGO:0007420970.044
negative regulation of proteolysisGO:00458611320.044
negative regulation of organelle organizationGO:00106391260.044
rhythmic behaviorGO:000762220.044
regulation of anatomical structure morphogenesisGO:00226032860.044
neuron developmentGO:00486661130.043
Rat
regulation of transmembrane transporter activityGO:0022898740.043
membrane raft localizationGO:005166510.043
regulation of dna metabolic processGO:00510521530.043
positive regulation of locomotionGO:00400171860.043
Rat
lipid metabolic processGO:00066293810.043
actin cytoskeleton organizationGO:00300362070.043
Yeast
proteolysis involved in cellular protein catabolic processGO:00516032440.043
organelle inheritanceGO:004830820.042
Rat
regulation of antigen receptor mediated signaling pathwayGO:0050854100.042
monovalent inorganic cation transportGO:00156721280.042
positive regulation of cytoskeleton organizationGO:0051495830.042
cellular response to growth factor stimulusGO:00713631970.042
positive regulation of immune system processGO:00026842830.041
positive regulation of purine nucleotide catabolic processGO:00331231850.041
Rat
peptidyl lysine acetylationGO:00183941010.041
negative regulation of protein complex assemblyGO:0031333430.041
disruption of cells of other organism involved in symbiotic interactionGO:005181830.040
centrosome separationGO:005129930.040
regulation of proteolysis involved in cellular protein catabolic processGO:1903050910.040
positive regulation of purine nucleotide metabolic processGO:19005442270.040
Rat
regulation of growthGO:00400081650.040
regenerationGO:003109940.040
ribonucleoside triphosphate catabolic processGO:00092033910.040
Rat
response to oxidative stressGO:00069791210.040
Rat
regulation of secretion by cellGO:19035301770.039
positive regulation of ruffle assemblyGO:190002940.039
cardiovascular system developmentGO:00723582620.039
Mouse
rho protein signal transductionGO:0007266260.039
regulation of vesicle mediated transportGO:00606271300.039
cellular response to granulocyte macrophage colony stimulating factor stimulusGO:009701130.039
negative regulation of cell cycle processGO:00109481210.039
striated muscle cell differentiationGO:0051146430.038
purine ribonucleotide catabolic processGO:00091544040.038
Rat
regulation of protein targetingGO:1903533910.038
reproductive processGO:00224141060.038
Yeast Mouse Worm Fly
regulation of protein catabolic processGO:00421761550.038
g1 s transition of mitotic cell cycleGO:0000082780.038
synaptic vesicle localizationGO:009747950.037
protein maturationGO:00516042330.037
regulation of mitotic cell cycle phase transitionGO:19019901180.037
regulation of developmental pigmentationGO:004807020.037
positive regulation of jnk cascadeGO:0046330520.037
positive regulation of hepatic stellate cell activationGO:200049110.037
cell morphogenesis involved in neuron differentiationGO:0048667440.036
long chain fatty acid metabolic processGO:0001676300.036
dna damage induced protein phosphorylationGO:000697550.036
nuclear exportGO:0051168690.035
organelle assemblyGO:00709251760.035
purine ribonucleoside catabolic processGO:00461303980.034
Rat
central nervous system developmentGO:00074171230.034
immune response activating cell surface receptor signaling pathwayGO:0002429450.034
negative regulation of stress activated protein kinase signaling cascadeGO:0070303190.034
nuclear divisionGO:00002801280.034
Rat
peptidyl tyrosine modificationGO:00182121700.034
cellular component disassemblyGO:0022411920.033
t cell receptor signaling pathwayGO:0050852210.033
cellular response to oxygen containing compoundGO:19017012760.033
nucleotide catabolic processGO:00091664080.032
Rat
positive regulation of glial cell proliferationGO:006025220.032
translational initiationGO:0006413480.032
tissue morphogenesisGO:0048729960.032
organonitrogen compound biosynthetic processGO:19015662000.031
regulation of neuron deathGO:1901214560.031
regulation of synaptic vesicle transportGO:190280330.031
maintenance of locationGO:00512351120.031
regulation of actin polymerization or depolymerizationGO:0008064560.031
cellular response to biotic stimulusGO:0071216710.031
extrinsic apoptotic signaling pathwayGO:00971911190.031
positive regulation of cell motilityGO:20001471770.031
Rat
negative regulation of nervous system developmentGO:0051961280.031
vesicle mediated transportGO:00161923710.030
microtubule based processGO:00070172100.030
Rat
intrinsic apoptotic signaling pathwayGO:00971931270.030
regulation of cell fate commitmentGO:001045370.030
regulation of protein dephosphorylationGO:0035304180.030
single organism behaviorGO:0044708280.030
somatic muscle developmentGO:000752510.030
transmembrane receptor protein serine threonine kinase signaling pathwayGO:00071781250.030
platelet activationGO:0030168440.030
intermediate filament cytoskeleton organizationGO:0045104170.030
cellular hyperosmotic responseGO:007147440.029
positive regulation of apoptotic signaling pathwayGO:2001235700.029
regulation of proteasomal ubiquitin dependent protein catabolic processGO:0032434710.029
regulation of cyclic nucleotide biosynthetic processGO:0030802490.029
regulation of peptidyl serine dephosphorylationGO:190230820.029
positive regulation of cell growthGO:0030307480.029
adult locomotory behaviorGO:000834410.029

MAP2K1 disease predictions

DiseaseDO term IDSizeProbabilityFunc Analog Org
cardiovascular system diseaseDOID:12871060.261
cardiomyopathyDOID:0050700500.261
myopathyDOID:4231040.261
musculoskeletal system diseaseDOID:172230.261
muscular diseaseDOID:00800001140.261
heart diseaseDOID:114680.261
muscle tissue diseaseDOID:661130.261
disease of mental healthDOID:150700.060
intrinsic cardiomyopathyDOID:0060036500.051
dilated cardiomyopathyDOID:12930320.037