Homo sapiens

75 known processes

PRPS1

phosphoribosyl pyrophosphate synthetase 1

(Aliases: CMTX5,ARTS,DFN2,PPRibP,DFNX1,PRSI,KIAA0967)

PRPS1 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
carbohydrate derivative biosynthetic processGO:19011372070.191
Rat
post embryonic developmentGO:000979120.166
nucleosome assemblyGO:0006334500.159
vesicle mediated transportGO:00161923710.154
nucleoside phosphate biosynthetic processGO:19012931090.088
purine ribonucleoside metabolic processGO:00461284370.087
Rat
nucleoside biosynthetic processGO:0009163260.074
Rat
nucleotide biosynthetic processGO:00091651090.070
ras protein signal transductionGO:0007265730.067
ribonucleoside triphosphate metabolic processGO:00091994120.066
protein modification by small protein conjugationGO:00324463420.066
cellular amino acid metabolic processGO:00065201160.063
purine ribonucleotide catabolic processGO:00091544040.062
nucleoside triphosphate catabolic processGO:00091433940.061
single organism cellular localizationGO:19025803320.058
cytoplasmic transportGO:00164823790.058
nervous system developmentGO:00073992930.057
mitotic cell cycleGO:00002783260.057
protein ubiquitinationGO:00165673140.056
locomotory behaviorGO:000762610.056
purine ribonucleoside catabolic processGO:00461303980.055
ribonucleoside catabolic processGO:00424544060.054
small gtpase mediated signal transductionGO:0007264780.053
adult locomotory behaviorGO:000834410.052
cellular amine metabolic processGO:0044106410.052
histone modificationGO:00165702510.051
chromatin assembly or disassemblyGO:0006333780.048
anterior posterior axis specificationGO:000994820.047
cell projection organizationGO:00300302520.045
nucleoside triphosphate metabolic processGO:00091414220.044
nucleoside phosphate catabolic processGO:19012924120.043
urate metabolic processGO:0046415110.043
chromatin assemblyGO:0031497610.043
oogenesisGO:004847720.042
chromatin modificationGO:00165682980.042
transmembrane transportGO:00550853990.042
nuclear divisionGO:00002801280.041
apoptotic signaling pathwayGO:00971902680.041
chromatin organizationGO:00063253510.041
dna strand elongation involved in dna replicationGO:000627130.040
nucleobase biosynthetic processGO:004611240.039
regulation of meiotic cell cycleGO:005144540.039
amine metabolic processGO:0009308440.038
ribose phosphate biosynthetic processGO:0046390820.038
Rat
guanosine containing compound catabolic processGO:19010692390.037
dna conformation changeGO:00711031130.037
purine nucleotide biosynthetic processGO:0006164840.037
response to abiotic stimulusGO:00096283360.037
nucleoside catabolic processGO:00091644080.037
cell morphogenesisGO:00009022960.037
ribonucleotide catabolic processGO:00092614050.036
cellular component disassemblyGO:0022411920.035
regulation of intracellular protein transportGO:00331571230.035
positive regulation of apoptotic processGO:00430652460.035
growthGO:00400072020.035
proteolysis involved in cellular protein catabolic processGO:00516032440.035
purine ribonucleoside triphosphate catabolic processGO:00092073910.034
neuron developmentGO:00486661130.034
nuclear migrationGO:000709710.034
purine nucleoside triphosphate metabolic processGO:00091444120.033
protein modification by small protein removalGO:0070646920.033
neuron differentiationGO:00301821380.033
mitotic cell cycle processGO:19030472860.033
glycosyl compound catabolic processGO:19016584130.033
cell developmentGO:00484683280.032
nitrogen compound transportGO:00717051910.032
regulation of proteolysisGO:00301622930.032
cell part morphogenesisGO:00329901370.031
single organism carbohydrate metabolic processGO:00447231930.031
reproductive processGO:00224141060.031
cellular macromolecular complex assemblyGO:00346223240.031
cellular protein catabolic processGO:00442572610.031
cellular macromolecule catabolic processGO:00442653800.030
purine containing compound biosynthetic processGO:0072522880.030
organophosphate catabolic processGO:00464344300.029
ornithine metabolic processGO:000659130.029
ribonucleoside monophosphate metabolic processGO:00091611870.029
Rat
generation of neuronsGO:00486991520.029
sex differentiationGO:0007548450.029
alpha amino acid metabolic processGO:1901605720.029
regulation of small gtpase mediated signal transductionGO:00510561560.029
purine containing compound catabolic processGO:00725234110.028
response to other organismGO:00517072610.028
nucleus localizationGO:005164710.028
positive regulation of transferase activityGO:00513472270.028
regulation of growthGO:00400081650.028
guanosine containing compound metabolic processGO:19010682440.027
purine nucleoside catabolic processGO:00061523980.026
cellular component morphogenesisGO:00329893140.026
reproductive structure developmentGO:0048608550.026
organic acid biosynthetic processGO:0016053970.026
nucleotide catabolic processGO:00091664080.025
negative regulation of cellular component organizationGO:00511292350.025
mitochondrion organizationGO:00070051560.025
cellular response to endogenous stimulusGO:00714953360.025
regulation of cellular component movementGO:00512703340.025
cellular response to dna damage stimulusGO:00069743790.025
blastocyst developmentGO:000182430.025
purine nucleotide catabolic processGO:00061954050.025
protein importGO:00170381300.025
negative regulation of protein metabolic processGO:00512483910.025
cellular ketone metabolic processGO:0042180800.025
protein catabolic processGO:00301633250.024
nucleoside monophosphate metabolic processGO:00091231910.024
Rat
positive regulation of cellular amino acid metabolic processGO:004576430.024
nucleosome organizationGO:0034728660.024
negative regulation of meiotic cell cycleGO:005144720.024
dna catabolic processGO:0006308490.024
establishment of organelle localizationGO:0051656590.024
protein localization to organelleGO:00333652800.024
intracellular protein transportGO:00068862700.023
protein maturationGO:00516042330.023
photoreceptor cell differentiationGO:004653020.023
negative regulation of intracellular signal transductionGO:19025321830.023
multicellular organismal agingGO:001025930.023
purine nucleoside triphosphate catabolic processGO:00091463920.022
modification dependent protein catabolic processGO:00199412090.022
positive regulation of developmental processGO:00510943140.022
organophosphate biosynthetic processGO:00904071630.022
negative regulation of programmed cell deathGO:00430693210.022
rna interferenceGO:001624640.022
cell morphogenesis involved in differentiationGO:00009041440.022
covalent chromatin modificationGO:00165692540.022
protein processingGO:00164852260.022
intrinsic apoptotic signaling pathwayGO:00971931270.021
regulation of transferase activityGO:00513383550.021
nuclear transportGO:00511691790.021
regulation of cellular response to stressGO:00801352440.021
organonitrogen compound biosynthetic processGO:19015662000.021
negative regulation of catalytic activityGO:00430863350.021
negative regulation of cell differentiationGO:00455961710.021
histone exchangeGO:004348630.020
mitotic nuclear divisionGO:00070671190.020
carbohydrate metabolic processGO:00059752070.020
dna packagingGO:0006323770.020
regulation of ligase activityGO:0051340290.020
regulation of ras protein signal transductionGO:00465781550.020
embryo developmentGO:00097901230.020
Worm
regulation of cell differentiationGO:00455953930.020
regulation of protein catabolic processGO:00421761550.020
positive regulation of feeding behaviorGO:200025310.019
purine ribonucleoside triphosphate metabolic processGO:00092054110.019
defense responseGO:00069523150.019
regulation of nucleotide metabolic processGO:00061402690.018
cellular response to oxygen containing compoundGO:19017012760.018
blastoderm segmentationGO:000735020.018
negative regulation of peptidase activityGO:0010466910.018
establishment of nucleus localizationGO:004002310.018
regulation of cell morphogenesis involved in differentiationGO:0010769830.018
positive regulation of immune system processGO:00026842830.018
neuron projection developmentGO:00311751060.018
nucleocytoplasmic transportGO:00069131760.018
cell projection morphogenesisGO:00488581290.018
negative regulation of apoptotic processGO:00430663160.018
purine ribonucleoside monophosphate metabolic processGO:00091671860.018
Rat
regulation of meiosisGO:004002030.017
ribonucleoside biosynthetic processGO:0042455250.017
Rat
negative regulation of protein processingGO:00109551420.017
establishment or maintenance of cytoskeleton polarityGO:003095230.017
purine nucleoside monophosphate catabolic processGO:00091281580.017
modification dependent macromolecule catabolic processGO:00436322120.017
female gamete generationGO:000729220.017
organelle localizationGO:0051640840.017
regulation of sequence specific dna binding transcription factor activityGO:00510902110.017
microtubule based processGO:00070172100.017
ribonucleotide biosynthetic processGO:0009260810.017
Rat
intracellular mrna localizationGO:000829810.017
negative regulation of multicellular organismal processGO:00512413170.017
positive regulation of phosphorylationGO:00423273940.017
cellular response to hormone stimulusGO:00328701250.017
response to oxygen containing compoundGO:19017003690.016
regulation of apoptotic signaling pathwayGO:20012331750.016
regulation of immune responseGO:00507762010.016
regulation of cell growthGO:00015581350.016
single organism membrane organizationGO:00448022680.016
response to external biotic stimulusGO:00432072610.016
regulation of protein transportGO:00512232130.016
positive regulation of cellular amine metabolic processGO:003324070.016
regulation of protein targetingGO:1903533910.016
monocarboxylic acid metabolic processGO:00327871850.016
negative regulation of cell deathGO:00605483450.016
lipid metabolic processGO:00066293810.016
ubiquitin dependent protein catabolic processGO:00065112060.016
glutamine family amino acid metabolic processGO:0009064170.016
positive regulation of nf kappab transcription factor activityGO:0051092810.016
cellular response to cytokine stimulusGO:00713451810.015
regulation of protein localizationGO:00328802960.015
proteasomal protein catabolic processGO:00104981760.015
regulation of mitotic cell cycleGO:00073461890.015
regulation of protein maturationGO:19033171500.015
tripartite regional subdivisionGO:000735120.015
embryo development ending in birth or egg hatchingGO:0009792340.015
Worm
positive regulation of immune responseGO:00507781590.015
chordate embryonic developmentGO:0043009340.015
mrna metabolic processGO:00160711750.015
immune responseGO:00069553070.015
purine nucleoside monophosphate metabolic processGO:00091261860.015
Rat
response to drugGO:0042493810.015
establishment of protein localization to organelleGO:00725941720.014
behavioral defense responseGO:000220900.014
oxidation reduction processGO:00551143960.014
ribonucleoside monophosphate catabolic processGO:00091581580.014
establishment or maintenance of cell polarityGO:0007163310.014
lipid biosynthetic processGO:00086101770.014
dna replication independent nucleosome assemblyGO:0006336270.014
regulation of cellular amine metabolic processGO:0033238110.014
regulation of establishment of protein localizationGO:00702012420.014
regulation of behaviorGO:0050795820.014
segmentationGO:003528240.014
regulation of multi organism processGO:00439001570.014
regulation of endopeptidase activityGO:00525481700.014
regulation of protein modification by small protein conjugation or removalGO:19033201070.014
cell adhesionGO:00071553250.013
determination of adult lifespanGO:000834020.013
neurogenesisGO:00220081690.013
endocytosisGO:00068971590.013
mitochondrial transportGO:0006839600.013
response to radiationGO:00093141510.013
cellular response to nitrogen compoundGO:19016991440.013
negative regulation of cellular protein metabolic processGO:00322693530.013
leading strand elongationGO:000627210.013
nucleoside monophosphate catabolic processGO:00091251590.013
leukocyte activationGO:00453211640.013
nucleic acid phosphodiester bond hydrolysisGO:00903051020.013
negative regulation of hydrolase activityGO:00513461820.013
protein alkylationGO:0008213740.013
reproductionGO:0000003630.013
regulation of cellular ketone metabolic processGO:0010565500.013
cell activationGO:00017752130.013
regulation of cytoplasmic transportGO:19036491490.012
positive regulation of cell proliferationGO:00082843010.012
response to virusGO:00096151260.012
cell growthGO:00160491600.012
negative regulation of phosphorus metabolic processGO:00105632670.012
atp metabolic processGO:00460341760.012
protein localization to nucleusGO:00345041360.012
positive regulation of hydrolase activityGO:00513453310.012
regulation of nucleoside metabolic processGO:00091182090.012
positive regulation of apoptotic signaling pathwayGO:2001235700.012
detection of stimulusGO:0051606850.012
meiotic chromosome segregationGO:004513240.011
regulation of protein processingGO:00706131500.011
chromosome segregationGO:00070591140.011
protein targetingGO:00066051870.011
neuromuscular junction developmentGO:000752830.011
regulation of feeding behaviorGO:006025930.011
mitotic dna integrity checkpointGO:0044774300.011
anterior posterior axis specification embryoGO:000859520.011
positive regulation of growthGO:0045927580.011
cellular lipid metabolic processGO:00442553030.011
positive regulation of nucleoside metabolic processGO:00459791860.011
behaviorGO:00076101120.011
nuclear exportGO:0051168690.011
negative regulation of phosphate metabolic processGO:00459362670.011
translesion synthesisGO:001998580.011
negative regulation of transferase activityGO:00513481240.011
positive regulation of transmembrane transportGO:0034764410.011
small molecule biosynthetic processGO:00442831570.011
single organism nuclear importGO:19025931040.011
negative regulation of cellular catabolic processGO:0031330830.011
innate immune responseGO:00450871780.011
dna repairGO:00062811980.011
mapk cascadeGO:00001652880.011
regulation of mapk cascadeGO:00434082620.010
cardiac muscle cell contractionGO:008600340.010
protein dna complex subunit organizationGO:0071824800.010
oocyte developmentGO:004859910.010
protein deubiquitinationGO:0016579790.010
protein acylationGO:00435431380.010
glycosyl compound biosynthetic processGO:1901659270.010
Rat
negative regulation of endopeptidase activityGO:0010951840.010
sensory perceptionGO:00076001030.010
gonad developmentGO:0008406340.010
organic anion transportGO:00157111030.010
peptidyl glutamic acid modificationGO:001820040.010
ion transmembrane transportGO:00342203380.010
positive regulation of cellular catabolic processGO:00313312840.010
protein k63 linked ubiquitinationGO:0070534310.010
establishment of cell polarityGO:0030010220.010

PRPS1 disease predictions

DiseaseDO term IDSizeProbabilityFunc Analog Org
immune system diseaseDOID:29141550.090
sensory system diseaseDOID:00501552030.031
nervous system diseaseDOID:8634310.031
neurodegenerative diseaseDOID:12891020.019
central nervous system diseaseDOID:3311860.019
eye and adnexa diseaseDOID:14921500.017
cancerDOID:1621670.017
disease of cellular proliferationDOID:145661740.017
retinal degenerationDOID:8466890.016
eye diseaseDOID:56141490.016
retinal diseaseDOID:56791180.016
disease of mental healthDOID:150700.016
organ system cancerDOID:00506861640.011
neuromuscular diseaseDOID:440380.006
neuropathyDOID:870520.006
charcot marie tooth diseaseDOID:10595330.002
nonsyndromic deafnessDOID:0050563500.002
auditory system diseaseDOID:2742530.002
x linked diseaseDOID:0050735140.001
charcot marie tooth disease type xDOID:005054230.000