Homo sapiens

73 known processes

ENPP4

ectonucleotide pyrophosphatase/phosphodiesterase 4 (putative)

(Aliases: KIAA0879,NPP4)

ENPP4 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
cellular lipid metabolic processGO:00442553030.122
Human
cellular amine metabolic processGO:0044106410.111
Human
amine metabolic processGO:0009308440.098
Human
nucleoside phosphate catabolic processGO:19012924120.084
Human
nucleoside triphosphate catabolic processGO:00091433940.075
Human
organophosphate catabolic processGO:00464344300.066
Human
lipid metabolic processGO:00066293810.058
Human
nucleoside triphosphate metabolic processGO:00091414220.052
Human Yeast
cellular amino acid metabolic processGO:00065201160.051
transmembrane transportGO:00550853990.043
cellular ketone metabolic processGO:0042180800.043
phospholipid metabolic processGO:0006644990.042
Human
purine nucleoside triphosphate metabolic processGO:00091444120.042
anion transportGO:00068201610.040
Human
ras protein signal transductionGO:0007265730.040
negative regulation of cellular protein metabolic processGO:00322693530.040
Human
regulation of cellular ketone metabolic processGO:0010565500.039
purine nucleoside triphosphate catabolic processGO:00091463920.039
regulation of cellular amine metabolic processGO:0033238110.039
positive regulation of catabolic processGO:00098963100.037
cytoplasmic transportGO:00164823790.037
membrane lipid metabolic processGO:0006643530.036
Human
purine ribonucleoside triphosphate metabolic processGO:00092054110.036
regulation of cellular amino acid metabolic processGO:000652160.035
ribonucleoside catabolic processGO:00424544060.035
post embryonic developmentGO:000979120.035
positive regulation of cellular catabolic processGO:00313312840.034
negative regulation of protein metabolic processGO:00512483910.034
Human
nucleotide catabolic processGO:00091664080.034
ribonucleoside triphosphate catabolic processGO:00092033910.033
ribonucleoside triphosphate metabolic processGO:00091994120.033
cellular biogenic amine metabolic processGO:0006576340.032
Human
purine ribonucleoside metabolic processGO:00461284370.032
small gtpase mediated signal transductionGO:0007264780.032
purine containing compound catabolic processGO:00725234110.032
locomotory behaviorGO:000762610.032
ribonucleotide catabolic processGO:00092614050.031
purine ribonucleoside triphosphate catabolic processGO:00092073910.031
system processGO:00030083490.031
multicellular organismal agingGO:001025930.030
nucleoside catabolic processGO:00091644080.030
organic anion transportGO:00157111030.029
membrane organizationGO:00610242920.029
purine nucleotide catabolic processGO:00061954050.029
positive regulation of hydrolase activityGO:00513453310.029
negative regulation of phosphorus metabolic processGO:00105632670.029
Human
cellular macromolecule catabolic processGO:00442653800.028
positive regulation of nucleotide metabolic processGO:00459812300.028
purine ribonucleotide catabolic processGO:00091544040.028
determination of adult lifespanGO:000834020.028
purine nucleoside catabolic processGO:00061523980.028
regulation of purine nucleotide metabolic processGO:19005422640.028
immune responseGO:00069553070.027
positive regulation of transportGO:00510503360.027
positive regulation of nucleoside metabolic processGO:00459791860.027
positive regulation of purine nucleotide metabolic processGO:19005442270.027
positive regulation of cellular amine metabolic processGO:003324070.026
glycosyl compound catabolic processGO:19016584130.026
ethanolamine containing compound metabolic processGO:0042439260.026
Human
negative regulation of catalytic activityGO:00430863350.026
cation transportGO:00068123310.026
cellular amide metabolic processGO:0043603690.026
Human
guanosine containing compound metabolic processGO:19010682440.025
guanosine containing compound catabolic processGO:19010692390.025
chemical homeostasisGO:00488783060.025
Human
positive regulation of nucleotide catabolic processGO:00308131850.025
neuromuscular junction developmentGO:000752830.025
ion homeostasisGO:00508012300.025
Human
vesicle mediated transportGO:00161923710.025
regulation of purine nucleotide catabolic processGO:00331212050.025
regulation of gtp catabolic processGO:00331241800.024
regulation of nucleotide metabolic processGO:00061402690.024
cellular response to nutrient levelsGO:0031669690.024
Yeast
single organism cellular localizationGO:19025803320.024
defense responseGO:00069523150.024
segmentationGO:003528240.023
positive regulation of purine nucleotide catabolic processGO:00331231850.023
negative regulation of phosphate metabolic processGO:00459362670.023
Human
negative regulation of cellular component organizationGO:00511292350.023
memoryGO:000761330.023
cellular response to external stimulusGO:00714961110.023
Yeast
positive regulation of cellular amino acid metabolic processGO:004576430.022
ion transmembrane transportGO:00342203380.022
protein catabolic processGO:00301633250.022
lipid biosynthetic processGO:00086101770.022
carbohydrate metabolic processGO:00059752070.022
Human
response to abiotic stimulusGO:00096283360.022
protein localization to organelleGO:00333652800.022
regulation of ion transportGO:00432691890.022
modification dependent protein catabolic processGO:00199412090.022
regulation of proteolysisGO:00301622930.022
intracellular protein transportGO:00068862700.022
cellular response to starvationGO:0009267580.021
Yeast
regulation of nucleotide catabolic processGO:00308112050.021
nervous system developmentGO:00073992930.021
cellular homeostasisGO:00197251960.021
Human
carbohydrate derivative biosynthetic processGO:19011372070.021
protein modification by small protein conjugationGO:00324463420.021
regulation of cellular response to stressGO:00801352440.021
hindbrain developmentGO:003090230.021
regulation of cellular component movementGO:00512703340.021
regulation of nucleoside metabolic processGO:00091182090.021
protein ubiquitinationGO:00165673140.021
positive regulation of cell proliferationGO:00082843010.020
rho protein signal transductionGO:0007266260.020
regulation of kinase activityGO:00435493140.020
actin filament based processGO:00300292240.020
purine ribonucleoside catabolic processGO:00461303980.020
cellular protein catabolic processGO:00442572610.020
cation homeostasisGO:00550801890.020
response to oxygen containing compoundGO:19017003690.020
Human
cytokine productionGO:00018162470.020
regulation of transferase activityGO:00513383550.020
sphingolipid metabolic processGO:0006665380.020
Human
cellular response to oxygen containing compoundGO:19017012760.020
Human
proteolysis involved in cellular protein catabolic processGO:00516032440.019
single organism membrane organizationGO:00448022680.019
cellular cation homeostasisGO:00300031630.019
modification dependent macromolecule catabolic processGO:00436322120.019
negative regulation of phosphorylationGO:00423261740.019
Human
gtp catabolic processGO:00061842370.019
regulation of protein localizationGO:00328802960.019
positive regulation of cellular component organizationGO:00511303760.019
mapk cascadeGO:00001652880.019
adult locomotory behaviorGO:000834410.019
regulation of gtpase activityGO:00430871800.018
gtp metabolic processGO:00460392390.018
epithelium developmentGO:00604292270.018
negative regulation of protein modification processGO:00314002000.018
Human
inorganic ion transmembrane transportGO:00986602310.018
regulation of cytokine productionGO:00018172320.018
regulation of establishment of protein localizationGO:00702012420.018
blastoderm segmentationGO:000735020.018
regulation of cell motilityGO:20001452990.018
positive regulation of gtpase activityGO:00435471660.018
dephosphorylationGO:00163112090.018
signal transduction by phosphorylationGO:00230142970.018
protein maturationGO:00516042330.018
negative regulation of multicellular organismal processGO:00512413170.018
cell adhesionGO:00071553250.018
positive regulation of gtp catabolic processGO:00331261660.018
regulation of intracellular transportGO:00323861950.017
spermatid differentiationGO:004851540.017
positive regulation of phosphorylationGO:00423273940.017
inner ear morphogenesisGO:004247240.017
positive regulation of transferase activityGO:00513472270.017
negative regulation of programmed cell deathGO:00430693210.017
cellular macromolecular complex assemblyGO:00346223240.017
small molecule biosynthetic processGO:00442831570.017
negative regulation of intracellular signal transductionGO:19025321830.017
negative regulation of cellular amino acid metabolic processGO:004576320.017
apoptotic signaling pathwayGO:00971902680.017
regulation of protein transportGO:00512232130.017
regulation of ras protein signal transductionGO:00465781550.016
response to other organismGO:00517072610.016
choline metabolic processGO:001969510.016
Human
ubiquitin dependent protein catabolic processGO:00065112060.016
regulation of mapk cascadeGO:00434082620.016
response to biotic stimulusGO:00096072760.016
protein processingGO:00164852260.016
regulation of cell cycleGO:00517263930.016
metal ion transportGO:00300012720.016
endomembrane system organizationGO:00102561960.016
glycerolipid metabolic processGO:00464861070.016
negative regulation of cell deathGO:00605483450.016
regulation of cell differentiationGO:00455953930.016
Human
innate immune responseGO:00450871780.016
single organism carbohydrate metabolic processGO:00447231930.016
Human
positive regulation of immune system processGO:00026842830.016
regulation of defense responseGO:00313471540.016
negative regulation of apoptotic processGO:00430663160.016
neurological system processGO:00508771630.016
organ formationGO:004864530.016
negative regulation of transportGO:00510511760.016
Human
cofactor metabolic processGO:0051186870.016
divalent inorganic cation homeostasisGO:00725071360.016
inorganic cation transmembrane transportGO:00986621940.016
nitrogen compound transportGO:00717051910.016
anterior posterior axis specificationGO:000994820.016
biological adhesionGO:00226103310.016
regulation of response to external stimulusGO:00321012220.016
regulation of protein kinase activityGO:00458592890.015
oogenesisGO:004847720.015
regulation of sequence specific dna binding transcription factor activityGO:00510902110.015
cell projection organizationGO:00300302520.015
organic acid biosynthetic processGO:0016053970.015
monocarboxylic acid metabolic processGO:00327871850.015
female gamete generationGO:000729220.015
regulation of ras gtpase activityGO:00323181280.015
mitochondrion organizationGO:00070051560.015
regulation of apoptotic signaling pathwayGO:20012331750.015
regulation of anatomical structure morphogenesisGO:00226032860.015
response to external biotic stimulusGO:00432072610.015
cellular component morphogenesisGO:00329893140.015
fatty acid metabolic processGO:00066311150.015
i kappab kinase nf kappab signalingGO:00072491660.015
proteasome mediated ubiquitin dependent protein catabolic processGO:00431611560.015
negative regulation of cellular amine metabolic processGO:003323930.015
cellular response to dna damage stimulusGO:00069743790.015
cation transmembrane transportGO:00986552380.015
cellular response to endogenous stimulusGO:00714953360.015
Human
spermatid developmentGO:000728640.015
purine ribonucleoside monophosphate metabolic processGO:00091671860.015
negative regulation of hydrolase activityGO:00513461820.015
ribonucleoside monophosphate metabolic processGO:00091611870.015
sequestering of metal ionGO:0051238240.014
alcohol metabolic processGO:00060661140.014
Human
metal ion homeostasisGO:00550651690.014
organonitrogen compound biosynthetic processGO:19015662000.014
organophosphate biosynthetic processGO:00904071630.014
reactive oxygen species metabolic processGO:0072593750.014
positive regulation of cellular component movementGO:00512721810.014
regulation of cellular component biogenesisGO:00440872810.014
protein targetingGO:00066051870.014
response to extracellular stimulusGO:0009991850.014
Yeast
cell activationGO:00017752130.014
cellular metal ion homeostasisGO:00068751460.014
atp metabolic processGO:00460341760.014
multi organism cellular processGO:00447641560.014
rab protein signal transductionGO:003248240.014
regulation of dna replicationGO:0006275680.014
Human
regulation of small gtpase mediated signal transductionGO:00510561560.014
nucleoside monophosphate metabolic processGO:00091231910.014
regulation of locomotionGO:00400123290.014
regulation of protein catabolic processGO:00421761550.014
circulatory system developmentGO:00723592620.013
organic hydroxy compound metabolic processGO:19016151470.013
Human
oocyte differentiationGO:000999420.013
purine nucleoside monophosphate metabolic processGO:00091261860.013
negative regulation of dna replicationGO:0008156290.013
Human
oxidation reduction processGO:00551143960.013
Human
immune effector processGO:00022521590.013
positive regulation of programmed cell deathGO:00430682490.013
tripartite regional subdivisionGO:000735120.013
cell morphogenesisGO:00009022960.013
divalent inorganic cation transportGO:00725111580.013
cardiac muscle cell contractionGO:008600340.013
regulation of reactive oxygen species biosynthetic processGO:190342630.013
posttranscriptional regulation of gene expressionGO:00106082130.013
oocyte developmentGO:004859910.013
establishment of protein localization to organelleGO:00725941720.013
proteasomal protein catabolic processGO:00104981760.013
monovalent inorganic cation transportGO:00156721280.013
regulation of multi organism processGO:00439001570.013
negative regulation of protein phosphorylationGO:00019331400.013
Human
positive regulation of locomotionGO:00400171860.013
associative learningGO:000830610.013
response to woundingGO:00096111680.013
regulation of cell growthGO:00015581350.013
Human
regulation of i kappab kinase nf kappab signalingGO:00431221620.013
sequestering of calcium ionGO:0051208170.013
carboxylic acid biosynthetic processGO:0046394970.013
regulation of cell migrationGO:00303342890.013
photoreceptor cell differentiationGO:004653020.013
maintenance of locationGO:00512351120.013
Human
regulation of immune responseGO:00507762010.013
regulation of cytoplasmic transportGO:19036491490.013
cellular carbohydrate metabolic processGO:0044262840.013
Human
regulation of synaptic plasticityGO:004816730.013
cellular protein complex assemblyGO:00436231880.012
glycoprotein metabolic processGO:00091001100.012
cell growthGO:00160491600.012
Human
cell developmentGO:00484683280.012
regulation of cell adhesionGO:00301551660.012
mitotic cell cycle processGO:19030472860.012
regenerationGO:003109940.012
mitotic cell cycleGO:00002783260.012
positive regulation of cell deathGO:00109422630.012
glycosylationGO:0070085710.012
actin filament based movementGO:0030048170.012
cellular ion homeostasisGO:00068731680.012
Human
response to nutrient levelsGO:0031667810.012
Yeast
matingGO:000761810.012
metencephalon developmentGO:002203720.012
rhythmic behaviorGO:000762220.012
compound eye developmentGO:004874910.012
microtubule based processGO:00070172100.012
regulation of neural precursor cell proliferationGO:200017740.012
positive regulation of reactive oxygen species biosynthetic processGO:190342820.012
regulation of transmembrane transportGO:00347621390.012
anterior posterior axis specification embryoGO:000859520.012
positive regulation of cytokine productionGO:00018191670.012
peripheral nervous system developmentGO:000742220.012
negative regulation of developmental processGO:00510932470.012
Human
enzyme linked receptor protein signaling pathwayGO:00071673030.012
Human
regulation of protein complex assemblyGO:00432541470.012
regulation of vesicle mediated transportGO:00606271300.012
actin mediated cell contractionGO:0070252120.012
endosomal transportGO:00161971290.012
response to nitrogen compoundGO:19016981840.012
Human
positive regulation of i kappab kinase nf kappab signalingGO:00431231320.012
circadian behaviorGO:004851220.012
divalent metal ion transportGO:00708381520.012
calcium ion transportGO:00068161470.012
regulation of metal ion transportGO:00109591200.012
glycoprotein biosynthetic processGO:0009101910.012
cardiovascular system developmentGO:00723582620.012
regulation of secretionGO:00510461940.011
cellular response to growth factor stimulusGO:00713631970.011
regulation of membrane potentialGO:0042391950.011
anatomical structure formation involved in morphogenesisGO:00486462840.011
cell fate determinationGO:000170930.011
positive regulation of cell migrationGO:00303351720.011
embryonic epithelial tube formationGO:000183840.011
positive regulation of cell motilityGO:20001471770.011
nerve developmentGO:002167540.011
positive regulation of reactive oxygen species metabolic processGO:2000379240.011
neurotransmitter secretionGO:000726940.011
negative regulation of transferase activityGO:00513481240.011
regulation of homeostatic processGO:00328441210.011
symbiosis encompassing mutualism through parasitismGO:00444031560.011
positive regulation of ras gtpase activityGO:00323201170.011
cellular chemical homeostasisGO:00550821800.011
Human
cerebellum developmentGO:002154920.011
reactive nitrogen species metabolic processGO:200105730.011
nucleoside monophosphate catabolic processGO:00091251590.011
motor neuron axon guidanceGO:000804520.011
stress activated protein kinase signaling cascadeGO:0031098940.011
hemopoiesisGO:00300971800.011
positive regulation of cell differentiationGO:00455972110.011
lipid localizationGO:00108761060.011
Human
establishment of protein localization to membraneGO:00901501210.011
morphogenesis of embryonic epitheliumGO:001633140.011
interspecies interaction between organismsGO:00444191560.011
positive regulation of apoptotic processGO:00430652460.011
anion transmembrane transportGO:0098656760.011
purine ribonucleoside monophosphate catabolic processGO:00091691580.011
positive regulation of mapk cascadeGO:00434101900.011
organ morphogenesisGO:00098871470.011
central nervous system developmentGO:00074171230.011
positive regulation of immune responseGO:00507781590.011
negative regulation of organelle organizationGO:00106391260.011
response to growth factorGO:00708482050.011
positive regulation of developmental processGO:00510943140.011
plasma membrane organizationGO:00070091150.011
glycerophospholipid metabolic processGO:0006650840.011
generation of neuronsGO:00486991520.011
response to fungusGO:000962040.011
negative regulation of cell cycleGO:00457861930.011
angiogenesisGO:00015251470.011
immune system developmentGO:00025201950.011
alpha amino acid metabolic processGO:1901605720.011
ribonucleoside monophosphate catabolic processGO:00091581580.011
regulation of reactive oxygen species metabolic processGO:2000377410.011
reactive oxygen species biosynthetic processGO:190340940.011
coenzyme metabolic processGO:0006732650.010
negative regulation of cell proliferationGO:00082852280.010
Human
striated muscle contractionGO:0006941520.010
cellular divalent inorganic cation homeostasisGO:00725031280.010
positive regulation of organelle organizationGO:00106381950.010
purine nucleoside monophosphate catabolic processGO:00091281580.010
cell divisionGO:00513011680.010
negative regulation of kinase activityGO:00336731060.010
neurogenesisGO:00220081690.010
regulation of intracellular protein transportGO:00331571230.010
stress activated mapk cascadeGO:0051403930.010
regulation of ion transmembrane transportGO:00347651320.010
response to virusGO:00096151260.010
negative regulation of transcription from rna polymerase ii promoterGO:00001222810.010
organophosphate ester transportGO:0015748320.010
lipid transportGO:0006869900.010
negative regulation of immune system processGO:00026831360.010
long term memoryGO:000761620.010
actin cytoskeleton organizationGO:00300362070.010
sulfur compound metabolic processGO:00067901010.010
Human
protein glycosylationGO:0006486620.010
monocarboxylic acid biosynthetic processGO:0072330670.010
response to cytokineGO:00340972320.010
regulation of stress activated protein kinase signaling cascadeGO:0070302850.010
positive regulation of kinase activityGO:00336742040.010
regulation of endopeptidase activityGO:00525481700.010
regulation of protein serine threonine kinase activityGO:00719001790.010
secretionGO:00469032540.010

ENPP4 disease predictions

DiseaseDO term IDSizeProbabilityFunc Analog Org
inherited metabolic disorderDOID:6552420.036
Human
disease of metabolismDOID:00146672950.036
Human
musculoskeletal system diseaseDOID:172230.022
central nervous system diseaseDOID:3311860.020
nervous system diseaseDOID:8634310.020
sensory system diseaseDOID:00501552030.019
disease of cellular proliferationDOID:145661740.015
cancerDOID:1621670.015
connective tissue diseaseDOID:651090.015
muscular diseaseDOID:00800001140.014
hematopoietic system diseaseDOID:741000.013
immune system diseaseDOID:29141550.013
neurodegenerative diseaseDOID:12891020.013
eye diseaseDOID:56141490.012
eye and adnexa diseaseDOID:14921500.012
muscle tissue diseaseDOID:661130.012
organ system cancerDOID:00506861640.012
retinal diseaseDOID:56791180.011
bone diseaseDOID:0080001880.011
amino acid metabolic disorderDOID:9252500.011
myopathyDOID:4231040.011
brain diseaseDOID:936730.010