IMP: Integrative Multi-species Prediction

Homo sapiens

0 known processes

ACAP3

ArfGAP with coiled-coil, ankyrin repeat and PH domains 3

(Aliases: KIAA1716,CENTB5)

Ensembl: ENSG00000131584
Entrez: 116983
HGNC: 16754
HPRD: 10820
UniProtKB: Q8WTZ1
UniProtKB: Q96P50

Process Predictions
Disease Predictions

ACAP3 biological process predictions

Show only novel predictionsHighlight processes of functional analogs

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Biological process	GO term ID	Process size	Probability	Func Analog Org
purine ribonucleotide catabolic process	GO:0009154	404	0.309
ribonucleoside catabolic process	GO:0042454	406	0.220
glycosyl compound catabolic process	GO:1901658	413	0.194
nucleoside triphosphate metabolic process	GO:0009141	422	0.193
purine ribonucleoside catabolic process	GO:0046130	398	0.183
ribonucleoside triphosphate catabolic process	GO:0009203	391	0.182
purine nucleotide catabolic process	GO:0006195	405	0.164
small gtpase mediated signal transduction	GO:0007264	78	0.161
purine nucleoside catabolic process	GO:0006152	398	0.137
purine ribonucleoside triphosphate metabolic process	GO:0009205	411	0.135
purine ribonucleoside triphosphate catabolic process	GO:0009207	391	0.135
ribonucleoside triphosphate metabolic process	GO:0009199	412	0.130
ras protein signal transduction	GO:0007265	73	0.126
guanosine containing compound metabolic process	GO:1901068	244	0.126
gtp catabolic process	GO:0006184	237	0.126
ribonucleotide catabolic process	GO:0009261	405	0.119
gtp metabolic process	GO:0046039	239	0.117
purine nucleoside triphosphate catabolic process	GO:0009146	392	0.115
nucleotide catabolic process	GO:0009166	408	0.109
positive regulation of nucleotide catabolic process	GO:0030813	185	0.108
purine containing compound catabolic process	GO:0072523	411	0.102
positive regulation of catabolic process	GO:0009896	310	0.100
positive regulation of rab gtpase activity	GO:0032851	39	0.097
endodermal cell fate commitment	GO:0001711	4	0.096
purine nucleoside triphosphate metabolic process	GO:0009144	412	0.096
cartilage condensation	GO:0001502	1	0.092
positive regulation of cellular component organization	GO:0051130	376	0.089
positive regulation of purine nucleotide metabolic process	GO:1900544	227	0.088
purine ribonucleoside metabolic process	GO:0046128	437	0.083
nucleoside catabolic process	GO:0009164	408	0.082
regulation of cellular component biogenesis	GO:0044087	281	0.081
organophosphate catabolic process	GO:0046434	430	0.073
positive regulation of purine nucleotide catabolic process	GO:0033123	185	0.064
nucleoside phosphate catabolic process	GO:1901292	412	0.063
regulation of purine nucleotide metabolic process	GO:1900542	264	0.062
regulation of nucleotide catabolic process	GO:0030811	205	0.057
regulation of nucleoside metabolic process	GO:0009118	209	0.056
regulation of ras protein signal transduction	GO:0046578	155	0.056
cell cell junction maintenance	GO:0045217	4	0.055
positive regulation of nucleotide metabolic process	GO:0045981	230	0.054
cellular amino acid metabolic process	GO:0006520	116	0.053
regulation of nucleotide metabolic process	GO:0006140	269	0.053
positive regulation of cellular catabolic process	GO:0031331	284	0.051
actin filament based process	GO:0030029	224	0.051
positive regulation of gtp catabolic process	GO:0033126	166	0.050
actin cytoskeleton organization	GO:0030036	207	0.050
positive regulation of gtpase activity	GO:0043547	166	0.049
regulation of purine nucleotide catabolic process	GO:0033121	205	0.049
regulation of cytoskeleton organization	GO:0051493	177	0.047
post embryonic development	GO:0009791	2	0.047
rab protein signal transduction	GO:0032482	4	0.047
guanosine containing compound catabolic process	GO:1901069	239	0.044
positive regulation of hydrolase activity	GO:0051345	331	0.043
actin filament organization	GO:0007015	128	0.043
protein catabolic process	GO:0030163	325	0.041
endodermal cell fate specification	GO:0001714	4	0.041
regulation of transferase activity	GO:0051338	355	0.040
cytoplasmic transport	GO:0016482	379	0.040
negative regulation of cellular component organization	GO:0051129	235	0.039
regulation of cellular amino acid metabolic process	GO:0006521	6	0.039
protein modification by small protein conjugation	GO:0032446	342	0.039
regulation of cellular amine metabolic process	GO:0033238	11	0.038
mitochondrion organization	GO:0007005	156	0.037
membrane organization	GO:0061024	292	0.036
regulation of small gtpase mediated signal transduction	GO:0051056	156	0.036
anatomical structure formation involved in morphogenesis	GO:0048646	284	0.035
cell junction maintenance	GO:0034331	4	0.034
protein localization to organelle	GO:0033365	280	0.033
regulation of gtp catabolic process	GO:0033124	180	0.033
nucleoside triphosphate catabolic process	GO:0009143	394	0.033
cellular macromolecule catabolic process	GO:0044265	380	0.033
cellular amine metabolic process	GO:0044106	41	0.032
regulation of protein kinase activity	GO:0045859	289	0.032
biological adhesion	GO:0022610	331	0.032
proteolysis involved in cellular protein catabolic process	GO:0051603	244	0.031
positive regulation of protein kinase activity	GO:0045860	190	0.031
cellular protein catabolic process	GO:0044257	261	0.031
zonula adherens maintenance	GO:0045218	3	0.031
lipid metabolic process	GO:0006629	381	0.031
cellular lipid metabolic process	GO:0044255	303	0.030
intracellular protein transport	GO:0006886	270	0.030
rho protein signal transduction	GO:0007266	26	0.030
positive regulation of cellular component biogenesis	GO:0044089	158	0.030
cellular macromolecular complex assembly	GO:0034622	324	0.029
positive regulation of transferase activity	GO:0051347	227	0.029
multicellular organismal aging	GO:0010259	3	0.029
female gamete generation	GO:0007292	2	0.028
cell adhesion	GO:0007155	325	0.028
regulation of proteolysis	GO:0030162	293	0.028
cell projection organization	GO:0030030	252	0.028
neurotransmitter secretion	GO:0007269	4	0.028
oogenesis	GO:0048477	2	0.027
cellular ketone metabolic process	GO:0042180	80	0.027
positive regulation of kinase activity	GO:0033674	204	0.027
positive regulation of cellular amine metabolic process	GO:0033240	7	0.027
positive regulation of protein phosphorylation	GO:0001934	313	0.027
vesicle mediated transport	GO:0016192	371	0.026	Fly
positive regulation of nucleoside metabolic process	GO:0045979	186	0.026
regulation of rab gtpase activity	GO:0032313	39	0.026
cellular protein complex assembly	GO:0043623	188	0.026
regeneration	GO:0031099	4	0.026
amine metabolic process	GO:0009308	44	0.026
regulation of ras gtpase activity	GO:0032318	128	0.025
negative regulation of programmed cell death	GO:0043069	321	0.025
negative regulation of phosphate metabolic process	GO:0045936	267	0.025
proteasomal protein catabolic process	GO:0010498	176	0.024
ubiquitin dependent protein catabolic process	GO:0006511	206	0.024
single organism cellular localization	GO:1902580	332	0.024
negative regulation of phosphorus metabolic process	GO:0010563	267	0.024
single organism membrane organization	GO:0044802	268	0.024
organonitrogen compound biosynthetic process	GO:1901566	200	0.024
regulation of cell differentiation	GO:0045595	393	0.023
protein localization to membrane	GO:0072657	160	0.023
regulation of anatomical structure morphogenesis	GO:0022603	286	0.023
protein processing	GO:0016485	226	0.023
regulation of kinase activity	GO:0043549	314	0.023
positive regulation of cellular amino acid metabolic process	GO:0045764	3	0.023
regulation of rab protein signal transduction	GO:0032483	39	0.023
regulation of cellular ketone metabolic process	GO:0010565	50	0.022
negative regulation of apoptotic process	GO:0043066	316	0.022
protein maturation	GO:0051604	233	0.021
protein targeting	GO:0006605	187	0.021
positive regulation of phosphorylation	GO:0042327	394	0.021
embryonic epithelial tube formation	GO:0001838	4	0.021
oocyte differentiation	GO:0009994	2	0.021
regulation of cellular response to stress	GO:0080135	244	0.021
regulation of cell cycle process	GO:0010564	266	0.021
single organism cell adhesion	GO:0098602	179	0.020
regulation of protein complex assembly	GO:0043254	147	0.020
negative regulation of intracellular signal transduction	GO:1902532	183	0.020
negative regulation of protein metabolic process	GO:0051248	391	0.020
organophosphate biosynthetic process	GO:0090407	163	0.020
nervous system development	GO:0007399	293	0.020
endomembrane system organization	GO:0010256	196	0.020
signal transduction by phosphorylation	GO:0023014	297	0.020
regulation of response to external stimulus	GO:0032101	222	0.020
negative regulation of cell death	GO:0060548	345	0.019
oocyte development	GO:0048599	1	0.019
somatic muscle development	GO:0007525	1	0.019
actin filament bundle assembly	GO:0051017	54	0.019
transmembrane transport	GO:0055085	399	0.019
mitotic cell cycle	GO:0000278	326	0.019
positive regulation of protein serine threonine kinase activity	GO:0071902	119	0.019
negative regulation of catalytic activity	GO:0043086	335	0.019
regulation of protein transport	GO:0051223	213	0.019
positive regulation of ras gtpase activity	GO:0032320	117	0.019
positive regulation of cell differentiation	GO:0045597	211	0.019
cell fate determination	GO:0001709	3	0.018
regulation of gtpase activity	GO:0043087	180	0.018
cell division	GO:0051301	168	0.018
protein targeting to membrane	GO:0006612	42	0.018
microtubule based process	GO:0007017	210	0.018
establishment of protein localization to organelle	GO:0072594	172	0.018
determination of adult lifespan	GO:0008340	2	0.018
regulation of protein localization	GO:0032880	296	0.018
purine ribonucleoside monophosphate metabolic process	GO:0009167	186	0.017
negative regulation of organelle organization	GO:0010639	126	0.017
regulation of cell projection organization	GO:0031344	107	0.017
apoptotic signaling pathway	GO:0097190	268	0.017
cell projection assembly	GO:0030031	126	0.017
monocarboxylic acid metabolic process	GO:0032787	185	0.017
positive regulation of organelle organization	GO:0010638	195	0.017
carbohydrate derivative biosynthetic process	GO:1901137	207	0.017
respiratory gaseous exchange	GO:0007585	3	0.017
nuclear transport	GO:0051169	179	0.017
t cell differentiation in thymus	GO:0033077	4	0.017
regulation of cell cycle	GO:0051726	393	0.017
locomotory behavior	GO:0007626	1	0.017
negative regulation of cellular protein metabolic process	GO:0032269	353	0.017
neuroblast proliferation	GO:0007405	4	0.017
negative regulation of hydrolase activity	GO:0051346	182	0.017
cellular component morphogenesis	GO:0032989	314	0.017	Fly
protein ubiquitination	GO:0016567	314	0.017
spermatid differentiation	GO:0048515	4	0.016
mapk cascade	GO:0000165	288	0.016
macromolecular complex disassembly	GO:0032984	60	0.016
modification dependent macromolecule catabolic process	GO:0043632	212	0.016
regulation of protein catabolic process	GO:0042176	155	0.016
protein localization to nucleus	GO:0034504	136	0.016
regulation of intracellular transport	GO:0032386	195	0.016
neuromuscular junction development	GO:0007528	3	0.016
establishment of protein localization to membrane	GO:0090150	121	0.016
mitotic cell cycle process	GO:1903047	286	0.016
lung alveolus development	GO:0048286	4	0.016
segmentation	GO:0035282	4	0.015
spermatid development	GO:0007286	4	0.015
regulation of protein maturation	GO:1903317	150	0.015
blastoderm segmentation	GO:0007350	2	0.015
inorganic ion transmembrane transport	GO:0098660	231	0.015
response to fungus	GO:0009620	4	0.015
mitotic cell cycle phase transition	GO:0044772	162	0.015
autophagy	GO:0006914	88	0.015
phospholipid metabolic process	GO:0006644	99	0.015
regulation of establishment of protein localization	GO:0070201	242	0.015
oxidation reduction process	GO:0055114	396	0.015
syncytium formation by plasma membrane fusion	GO:0000768	2	0.015
salivary gland morphogenesis	GO:0007435	4	0.015
nucleocytoplasmic transport	GO:0006913	176	0.015
cdc42 protein signal transduction	GO:0032488	4	0.015
protein polymerization	GO:0051258	71	0.014
protein import	GO:0017038	130	0.014
regulation of cell morphogenesis	GO:0022604	153	0.014
protein targeting to nucleus	GO:0044744	104	0.014
respiratory system process	GO:0003016	3	0.014
nucleoside monophosphate metabolic process	GO:0009123	191	0.014
cell projection morphogenesis	GO:0048858	129	0.014
regulation of synaptic plasticity	GO:0048167	3	0.014
regulation of growth	GO:0040008	165	0.014
actin polymerization or depolymerization	GO:0008154	56	0.014
regulation of actin cytoskeleton organization	GO:0032956	116	0.014
dephosphorylation	GO:0016311	209	0.014
regulation of actin filament based process	GO:0032970	141	0.014
nuclear import	GO:0051170	106	0.014
metal ion transport	GO:0030001	272	0.014
cell morphogenesis	GO:0000902	296	0.014	Fly
regulation of neural precursor cell proliferation	GO:2000177	4	0.014
positive regulation of cell proliferation	GO:0008284	301	0.014
positive regulation of developmental process	GO:0051094	314	0.013
regulation of stress activated protein kinase signaling cascade	GO:0070302	85	0.013
negative regulation of protein maturation	GO:1903318	142	0.013
proteasome mediated ubiquitin dependent protein catabolic process	GO:0043161	156	0.013
organelle fission	GO:0048285	149	0.013
negative regulation of protein processing	GO:0010955	142	0.013
cellular component disassembly	GO:0022411	92	0.013
maintenance of location	GO:0051235	112	0.013
glycerolipid metabolic process	GO:0046486	107	0.013
atp metabolic process	GO:0046034	176	0.013
negative regulation of protein modification process	GO:0031400	200	0.013
endosomal transport	GO:0016197	129	0.013
regulation of apoptotic signaling pathway	GO:2001233	175	0.013
plasma membrane organization	GO:0007009	115	0.013
cell development	GO:0048468	328	0.013
positive regulation of synaptic transmission	GO:0050806	4	0.013
cell type specific apoptotic process	GO:0097285	125	0.013
protein polyubiquitination	GO:0000209	110	0.013
peptidyl tyrosine phosphorylation	GO:0018108	170	0.013
regulation of immune response	GO:0050776	201	0.013
head development	GO:0060322	108	0.013
cellular response to dna damage stimulus	GO:0006974	379	0.013
protein complex disassembly	GO:0043241	52	0.013
anion transport	GO:0006820	161	0.013
defense response	GO:0006952	315	0.013
g protein coupled receptor signaling pathway	GO:0007186	207	0.013
negative regulation of cellular amino acid metabolic process	GO:0045763	2	0.013
cell cell signaling	GO:0007267	155	0.013
thymic t cell selection	GO:0045061	2	0.013
neurogenesis	GO:0022008	169	0.012
negative regulation of protein phosphorylation	GO:0001933	140	0.012
positive regulation of transport	GO:0051050	336	0.012
anterior posterior axis specification	GO:0009948	2	0.012
hemopoiesis	GO:0030097	180	0.012
i kappab kinase nf kappab signaling	GO:0007249	166	0.012
cell cycle phase transition	GO:0044770	173	0.012
protein import into nucleus	GO:0006606	104	0.012
ribonucleoside monophosphate metabolic process	GO:0009161	187	0.012
startle response	GO:0001964	3	0.012
hematopoietic or lymphoid organ development	GO:0048534	186	0.012
tripartite regional subdivision	GO:0007351	2	0.012
single organismal cell cell adhesion	GO:0016337	148	0.012
innate immune response	GO:0045087	178	0.012
response to cytokine	GO:0034097	232	0.012
secretion	GO:0046903	254	0.012
mitotic nuclear division	GO:0007067	119	0.012
negative regulation of proteolysis	GO:0045861	132	0.012
regulation of protein processing	GO:0070613	150	0.012
positive regulation of cytokine production	GO:0001819	167	0.012
endodermal cell differentiation	GO:0035987	31	0.012
microtubule cytoskeleton organization	GO:0000226	176	0.012
small molecule catabolic process	GO:0044282	92	0.012
single organism nuclear import	GO:1902593	104	0.011
response to oxygen containing compound	GO:1901700	369	0.011
immune response	GO:0006955	307	0.011
regulation of sequence specific dna binding transcription factor activity	GO:0051090	211	0.011
epithelium development	GO:0060429	227	0.011
ion transmembrane transport	GO:0034220	338	0.011
morphogenesis of embryonic epithelium	GO:0016331	4	0.011
regulation of cellular component movement	GO:0051270	334	0.011
positive regulation of neural precursor cell proliferation	GO:2000179	2	0.011
central nervous system development	GO:0007417	123	0.011
purine nucleoside monophosphate metabolic process	GO:0009126	186	0.011
positive regulation of cell cycle process	GO:0090068	106	0.011
positive regulation of programmed cell death	GO:0043068	249	0.011
regulation of cell motility	GO:2000145	299	0.011
negative regulation of growth	GO:0045926	97	0.011
cell cycle checkpoint	GO:0000075	117	0.011
negative regulation of cellular amine metabolic process	GO:0033239	3	0.011
phosphatidylglycerol biosynthetic process	GO:0006655	3	0.011
negative regulation of multicellular organismal process	GO:0051241	317	0.011
inorganic cation transmembrane transport	GO:0098662	194	0.011
defense response to fungus	GO:0050832	4	0.011
endocytosis	GO:0006897	159	0.011	Fly
stress activated protein kinase signaling cascade	GO:0031098	94	0.011
posttranscriptional regulation of gene expression	GO:0010608	213	0.011
cellular homeostasis	GO:0019725	196	0.011
single organism carbohydrate metabolic process	GO:0044723	193	0.011
regulation of cell cycle phase transition	GO:1901987	126	0.011
organelle assembly	GO:0070925	176	0.011
regulation of mapk cascade	GO:0043408	262	0.011
adult locomotory behavior	GO:0008344	1	0.011
negative regulation of transcription from rna polymerase ii promoter	GO:0000122	281	0.011
regulation of intracellular protein transport	GO:0033157	123	0.011
regulation of cellular component size	GO:0032535	82	0.011
regulation of binding	GO:0051098	111	0.011
regulation of multi organism process	GO:0043900	157	0.011
peripheral nervous system development	GO:0007422	2	0.011
nadph oxidation	GO:0070995	3	0.011
organ formation	GO:0048645	3	0.011
metencephalon development	GO:0022037	2	0.011
myeloid cell differentiation	GO:0030099	117	0.011
regulation of anatomical structure size	GO:0090066	101	0.011
compound eye development	GO:0048749	1	0.011
inner ear morphogenesis	GO:0042472	4	0.011
regulation of cytokine production	GO:0001817	232	0.010
positive regulation of stress activated protein kinase signaling cascade	GO:0070304	61	0.010
actomyosin structure organization	GO:0031032	59	0.010
growth	GO:0040007	202	0.010
peptidyl tyrosine modification	GO:0018212	170	0.010
regulation of cell division	GO:0051302	116	0.010
negative regulation of catabolic process	GO:0009895	104	0.010
embryo development	GO:0009790	123	0.010
regulation of mitotic cell cycle phase transition	GO:1901990	118	0.010
chemical homeostasis	GO:0048878	306	0.010
memory	GO:0007613	3	0.010
regulation of vesicle mediated transport	GO:0060627	130	0.010
establishment of tissue polarity	GO:0007164	3	0.010
regulation of protein binding	GO:0043393	66	0.010
chemotaxis	GO:0006935	157	0.010
positive regulation of apoptotic process	GO:0043065	246	0.010
protein localization to plasma membrane	GO:0072659	93	0.010
organic hydroxy compound metabolic process	GO:1901615	147	0.010
regulation of cellular protein catabolic process	GO:1903362	96	0.010
endoderm formation	GO:0001706	33	0.010
regulation of mitosis	GO:0007088	63	0.010

ACAP3 disease predictions

Disease	DO term ID	Size	Probability
central nervous system disease	DOID:331	186	0.022
nervous system disease	DOID:863	431	0.022
musculoskeletal system disease	DOID:17	223	0.018
disease of metabolism	DOID:0014667	295	0.016
inherited metabolic disorder	DOID:655	242	0.014
sensory system disease	DOID:0050155	203	0.013
brain disease	DOID:936	73	0.012
muscle tissue disease	DOID:66	113	0.011
muscular disease	DOID:0080000	114	0.011
eye and adnexa disease	DOID:1492	150	0.011
eye disease	DOID:5614	149	0.011
disease of mental health	DOID:150	70	0.011
cancer	DOID:162	167	0.011
organ system cancer	DOID:0050686	164	0.011
disease of cellular proliferation	DOID:14566	174	0.011
myopathy	DOID:423	104	0.011

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