Homo sapiens

45 known processes

CFL2

cofilin 2 (muscle)

(Aliases: NEM7)

CFL2 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
actin myosin filament slidingGO:003327560.916
glomerular mesangial cell differentiationGO:007200820.849
skeletal muscle thin filament assemblyGO:003024030.772
nucleotide catabolic processGO:00091664080.613
purine containing compound catabolic processGO:00725234110.543
glomerular mesangial cell developmentGO:007214410.542
renal interstitial fibroblast developmentGO:007214110.542
nucleoside triphosphate catabolic processGO:00091433940.539
nucleoside monophosphate catabolic processGO:00091251590.534
glycosyl compound catabolic processGO:19016584130.529
nucleoside phosphate catabolic processGO:19012924120.521
microvillus organizationGO:003252820.519
purine nucleotide catabolic processGO:00061954050.509
atp catabolic processGO:00062001570.502
actin filament based movementGO:0030048170.500
purine nucleoside catabolic processGO:00061523980.482
purine ribonucleotide catabolic processGO:00091544040.479
purine ribonucleoside metabolic processGO:00461284370.459
purine nucleoside triphosphate catabolic processGO:00091463920.456
mesangial cell developmentGO:007214310.442
nucleoside triphosphate metabolic processGO:00091414220.434
ribonucleoside monophosphate metabolic processGO:00091611870.426
purine ribonucleoside triphosphate catabolic processGO:00092073910.413
purine nucleoside triphosphate metabolic processGO:00091444120.401
purine ribonucleoside catabolic processGO:00461303980.394
purine nucleoside monophosphate catabolic processGO:00091281580.389
ribonucleoside monophosphate catabolic processGO:00091581580.371
ribonucleotide catabolic processGO:00092614050.359
purine ribonucleoside triphosphate metabolic processGO:00092054110.351
nucleoside catabolic processGO:00091644080.342
ribonucleoside triphosphate catabolic processGO:00092033910.316
organophosphate catabolic processGO:00464344300.305
purine nucleoside monophosphate metabolic processGO:00091261860.285
purine ribonucleoside monophosphate catabolic processGO:00091691580.277
epithelial cell differentiation involved in kidney developmentGO:003585090.273
post embryonic developmentGO:000979120.248
ribonucleoside triphosphate metabolic processGO:00091994120.245
actin mediated cell contractionGO:0070252120.241
purine ribonucleoside monophosphate metabolic processGO:00091671860.232
atp metabolic processGO:00460341760.229
nucleoside monophosphate metabolic processGO:00091231910.228
ribonucleoside catabolic processGO:00424544060.222
chronological cell agingGO:000130020.206
embryonic epithelial tube formationGO:000183840.180
neural tube formationGO:000184130.179
circulatory system developmentGO:00723592620.174
organelle inheritanceGO:004830820.174
kidney interstitial fibroblast differentiationGO:007207120.163
plasma membrane organizationGO:00070091150.153
Yeast
protein acylationGO:00435431380.149
response to virusGO:00096151260.146
Human
positive regulation of catabolic processGO:00098963100.136
internal protein amino acid acetylationGO:00064751010.120
epithelium developmentGO:00604292270.119
tube developmentGO:00352951250.119
morphogenesis of embryonic epitheliumGO:001633140.119
cytoplasmic transportGO:00164823790.117
Yeast
anatomical structure formation involved in morphogenesisGO:00486462840.114
Mouse
system processGO:00030083490.112
response to external biotic stimulusGO:00432072610.109
Human
atp dependent chromatin remodelingGO:0043044250.109
biological adhesionGO:00226103310.109
cell differentiation involved in kidney developmentGO:006100590.102
kidney vasculature developmentGO:006144070.101
vacuole organizationGO:0007033440.101
retina homeostasisGO:0001895420.100
internal peptidyl lysine acetylationGO:0018393970.095
hemostasisGO:0007599760.094
secretion by cellGO:00329402260.094
glomerulus vasculature developmentGO:007201260.093
positive regulation of protein complex disassemblyGO:004324380.093
vesicle mediated transportGO:00161923710.093
Yeast
single organism cellular localizationGO:19025803320.088
Yeast
vasculature developmentGO:00019441810.087
establishment of protein localization to membraneGO:00901501210.087
Yeast
histone modificationGO:00165702510.086
cell divisionGO:00513011680.085
muscle structure developmentGO:0061061980.085
Mouse
cell adhesionGO:00071553250.085
blood coagulationGO:0007596760.082
chromatin modificationGO:00165682980.079
cellular component disassemblyGO:0022411920.076
positive regulation of locomotionGO:00400171860.074
single organismal cell cell adhesionGO:00163371480.073
peptidyl lysine modificationGO:00182051440.072
circulatory system processGO:00030131130.072
actin filament organizationGO:00070151280.072
regulation of purine nucleotide catabolic processGO:00331212050.072
skeletal myofibril assemblyGO:001486630.071
secretionGO:00469032540.071
single organism membrane organizationGO:00448022680.070
Yeast
regulation of cellular ketone metabolic processGO:0010565500.070
neural crest cell developmentGO:001403230.069
microvillus assemblyGO:003003320.067
tube morphogenesisGO:0035239950.066
peptidyl lysine acetylationGO:00183941010.066
covalent chromatin modificationGO:00165692540.065
cellular response to oxidative stressGO:0034599850.064
cardiovascular system developmentGO:00723582620.064
platelet aggregationGO:0070527320.064
blood circulationGO:00080151130.062
blood vessel developmentGO:00015681720.062
nervous system developmentGO:00073992930.061
Human
protein acetylationGO:00064731160.060
post golgi vesicle mediated transportGO:0006892360.060
Yeast
response to biotic stimulusGO:00096072760.059
Human
multicellular organismal homeostasisGO:0048871670.059
anatomical structure homeostasisGO:00602491000.059
Mouse
positive regulation of purine nucleotide catabolic processGO:00331231850.058
glomerulus developmentGO:0032835150.057
enzyme linked receptor protein signaling pathwayGO:00071673030.056
actin filament based processGO:00300292240.056
cell projection organizationGO:00300302520.055
Human
intracellular protein transportGO:00068862700.055
Yeast
midbrain developmentGO:0030901450.055
actin cytoskeleton organizationGO:00300362070.055
single organism cell adhesionGO:00986021790.055
dna repairGO:00062811980.054
response to oxidative stressGO:00069791210.054
cellular defense responseGO:000696820.054
positive regulation of protein depolymerizationGO:190188160.053
positive regulation of phosphorylationGO:00423273940.053
protein complex disassemblyGO:0043241520.053
regulation of cellular amino acid metabolic processGO:000652160.053
cytokinesisGO:0000910960.052
chromatin organizationGO:00063253510.052
histone acetylationGO:0016573930.051
response to woundingGO:00096111680.050
protein localization to organelleGO:00333652800.050
protein depolymerizationGO:0051261300.050
wound healingGO:00420601150.050
cellular response to endogenous stimulusGO:00714953360.049
cellular component morphogenesisGO:00329893140.049
Human Mouse
heart contractionGO:0060047620.048
positive regulation of cell motilityGO:20001471770.048
neural nucleus developmentGO:0048857470.047
positive regulation of cellular component movementGO:00512721810.046
tissue homeostasisGO:0001894630.046
positive regulation of nucleoside metabolic processGO:00459791860.046
central nervous system developmentGO:00074171230.046
brain developmentGO:0007420970.045
epithelial cell developmentGO:0002064340.045
negative regulation of cell sizeGO:004579230.044
salivary gland morphogenesisGO:000743540.044
actin filament severingGO:005101440.043
Yeast
epithelial cell differentiationGO:00308551410.043
regulation of nucleotide metabolic processGO:00061402690.043
nephron developmentGO:0072006300.042
cellular response to dna damage stimulusGO:00069743790.041
regulation of cell migrationGO:00303342890.041
regulation of body fluid levelsGO:0050878990.041
renal system developmentGO:0072001630.041
cellular amino acid metabolic processGO:00065201160.041
positive regulation of purine nucleotide metabolic processGO:19005442270.040
urogenital system developmentGO:0001655650.040
regulation of atpase activityGO:0043462250.039
regulation of nucleotide catabolic processGO:00308112050.039
dendritic spine developmentGO:006099660.039
Human
cell projection assemblyGO:00300311260.038
chromatin remodelingGO:0006338550.038
nuclear transportGO:00511691790.038
positive regulation of cellular component organizationGO:00511303760.038
regulation of atp metabolic processGO:1903578290.037
cellular ketone metabolic processGO:0042180800.037
heart processGO:0003015620.036
protein secretionGO:0009306980.036
positive regulation of cellular catabolic processGO:00313312840.036
dendritic spine organizationGO:009706140.036
Human
cell developmentGO:00484683280.035
Human Mouse
epithelium migrationGO:00901321190.035
negative regulation of multicellular organismal processGO:00512413170.034
primary neural tube formationGO:001402030.034
substantia nigra developmentGO:0021762450.034
endocytosisGO:00068971590.034
Yeast
regulation of cell projection organizationGO:00313441070.033
Human
neuromuscular junction developmentGO:000752830.033
regulation of nucleoside metabolic processGO:00091182090.032
locomotory behaviorGO:000762610.032
carbohydrate derivative biosynthetic processGO:19011372070.032
dendritic spine morphogenesisGO:006099730.032
Human
response to calcium ionGO:0051592460.031
amine metabolic processGO:0009308440.031
regulation of purine nucleotide metabolic processGO:19005422640.031
establishment of cell polarityGO:0030010220.031
kidney developmentGO:0001822530.031
regulation of atp catabolic processGO:1903289250.031
negative regulation of phosphate metabolic processGO:00459362670.031
positive regulation of nucleotide catabolic processGO:00308131850.031
regulation of actin polymerization or depolymerizationGO:0008064560.031
nucleocytoplasmic transportGO:00069131760.030
matingGO:000761810.030
response to other organismGO:00517072610.030
Human
regulation of cell differentiationGO:00455953930.030
Human
cell agingGO:0007569520.029
growthGO:00400072020.029
negative regulation of muscle contractionGO:004593230.029
negative regulation of cellular protein metabolic processGO:00322693530.028
homotypic cell cell adhesionGO:0034109470.028
regulation of cell motilityGO:20001452990.028
establishment of protein localization to organelleGO:00725941720.028
reproductive processGO:00224141060.028
platelet activationGO:0030168440.028
cellular protein complex disassemblyGO:0043624360.027
adult locomotory behaviorGO:000834410.027
female gamete generationGO:000729220.027
transmembrane transportGO:00550853990.026
coagulationGO:0050817780.026
cellular response to growth factor stimulusGO:00713631970.026
positive regulation of cellular amino acid metabolic processGO:004576430.026
regulation of protein kinase activityGO:00458592890.025
tissue migrationGO:00901301190.025
mitotic cell cycleGO:00002783260.025
negative regulation of phosphorus metabolic processGO:00105632670.025
positive regulation of cell deathGO:00109422630.024
regulation of cell cycleGO:00517263930.024
cellular protein complex assemblyGO:00436231880.024
mesangial cell differentiationGO:007200720.024
immune effector processGO:00022521590.023
gtp metabolic processGO:00460392390.023
organelle assemblyGO:00709251760.023
Mouse
positive regulation of intracellular protein transportGO:0090316760.023
positive regulation of hydrolase activityGO:00513453310.022
regulation of protein serine threonine kinase activityGO:00719001790.022
regulation of anatomical structure morphogenesisGO:00226032860.022
Human
positive regulation of nucleotide metabolic processGO:00459812300.022
memoryGO:000761330.022
embryo developmentGO:00097901230.021
muscle contractionGO:0006936730.021
negative regulation of organelle organizationGO:00106391260.021
guanosine containing compound catabolic processGO:19010692390.021
positive regulation of cytoskeleton organizationGO:0051495830.021
peripheral nervous system developmentGO:000742220.021
regulation of intracellular transportGO:00323861950.021
positive regulation of developmental processGO:00510943140.021
golgi vesicle transportGO:0048193800.021
Yeast
muscle cell developmentGO:0055001290.021
Mouse
anterior posterior axis specificationGO:000994820.021
reproductive system developmentGO:0061458560.021
response to acid chemicalGO:0001101660.021
regulation of protein complex assemblyGO:00432541470.021
cell projection morphogenesisGO:00488581290.021
Human
cell cell junction organizationGO:0045216690.020
tube closureGO:006060630.020
negative regulation of catalytic activityGO:00430863350.020
positive regulation of cell migrationGO:00303351720.020
protein targeting to membraneGO:0006612420.020
motor neuron axon guidanceGO:000804520.020
neural tube closureGO:000184330.020
positive regulation of kinase activityGO:00336742040.020
membrane organizationGO:00610242920.020
Yeast
regulation of meiotic cell cycleGO:005144540.019
regulation of cellular component movementGO:00512703340.019
mapk cascadeGO:00001652880.019
cytoskeleton dependent cytokinesisGO:0061640220.019
head developmentGO:00603221080.019
endomembrane system organizationGO:00102561960.019
Yeast
hindbrain developmentGO:003090230.019
regulation of neuron differentiationGO:0045664700.019
Human
mitotic cell cycle processGO:19030472860.019
endosomal transportGO:00161971290.019
striated muscle cell differentiationGO:0051146430.018
Mouse
positive regulation of protein kinase activityGO:00458601900.018
protein ubiquitinationGO:00165673140.018
muscle system processGO:0003012810.018
killing by host of symbiont cellsGO:005187320.018
positive regulation of intracellular transportGO:00323881040.018
tube formationGO:0035148100.018
regulation of establishment of protein localizationGO:00702012420.018
regulation of cellular amine metabolic processGO:0033238110.018
g protein coupled receptor signaling pathwayGO:00071862070.018
nerve developmentGO:002167540.018
regulation of gtp catabolic processGO:00331241800.018
cellular component assembly involved in morphogenesisGO:0010927730.018
Mouse
cellular macromolecule catabolic processGO:00442653800.018
organelle fissionGO:00482851490.018
receptor mediated endocytosisGO:0006898840.018
small gtpase mediated signal transductionGO:0007264780.017
glycosylationGO:0070085710.017
proteasome mediated ubiquitin dependent protein catabolic processGO:00431611560.017
cell junction organizationGO:0034330790.017
regulation of intracellular protein transportGO:00331571230.017
positive regulation of protein serine threonine kinase activityGO:00719021190.017
positive regulation of immune system processGO:00026842830.017
defense response to other organismGO:00985421290.017
fatty acid metabolic processGO:00066311150.017
tissue morphogenesisGO:0048729960.017
protein catabolic processGO:00301633250.017
cell growthGO:00160491600.017
cellular amine metabolic processGO:0044106410.017
carbohydrate metabolic processGO:00059752070.016
regulation of neuron projection developmentGO:0010975570.016
Human
negative regulation of cytokine productionGO:0001818820.016
proteolysis involved in cellular protein catabolic processGO:00516032440.016
response to nitrogen compoundGO:19016981840.016
response to amino acidGO:0043200140.016
organ morphogenesisGO:00098871470.016
spermatid differentiationGO:004851540.016
segmentationGO:003528240.016
disruption by host of symbiont cellsGO:005185220.016
regulation of gtpase activityGO:00430871800.016
regulation of protein catabolic processGO:00421761550.016
maintenance of locationGO:00512351120.016
negative regulation of cellular amine metabolic processGO:003323930.016
reactive oxygen species biosynthetic processGO:190340940.016
regulation of mitotic cell cycleGO:00073461890.016
positive regulation of protein phosphorylationGO:00019343130.016
reactive nitrogen species metabolic processGO:200105730.016
protein localization to nucleusGO:00345041360.016
negative regulation of cellular amino acid metabolic processGO:004576320.015
actin polymerization or depolymerizationGO:0008154560.015
negative regulation of cellular component organizationGO:00511292350.015
guanosine containing compound metabolic processGO:19010682440.015
positive regulation of cellular component biogenesisGO:00440891580.015
cranial nerve developmentGO:002154540.015
negative regulation of protein complex assemblyGO:0031333430.015
stem cell developmentGO:0048864690.015
striated muscle tissue developmentGO:0014706590.015
modification dependent protein catabolic processGO:00199412090.015
oogenesisGO:004847720.015
establishment or maintenance of cell polarityGO:0007163310.015
negative regulation of cell migrationGO:00303361020.015
positive regulation of organelle organizationGO:00106381950.014
immune responseGO:00069553070.014
rna interferenceGO:001624640.014
positive regulation of cell projection organizationGO:0031346640.014
transmission of nerve impulseGO:0019226110.014
regulation of locomotionGO:00400123290.014
ion homeostasisGO:00508012300.014
defense response to fungusGO:005083240.014
response to oxygen containing compoundGO:19017003690.014
single organism nuclear importGO:19025931040.014
regulation of cell cycle processGO:00105642660.014
neutrophil mediated immunityGO:000244640.014
connective tissue developmentGO:0061448390.014
embryonic morphogenesisGO:0048598850.014
chordate embryonic developmentGO:0043009340.014
negative regulation of intracellular signal transductionGO:19025321830.013
cellular lipid metabolic processGO:00442553030.013
organonitrogen compound biosynthetic processGO:19015662000.013
protein targeting to nucleusGO:00447441040.013
limbic system developmentGO:002176130.013
positive regulation of apoptotic processGO:00430652460.013
reproductive structure developmentGO:0048608550.013
anion transportGO:00068201610.013
positive regulation of mapk cascadeGO:00434101900.013
actomyosin structure organizationGO:0031032590.013
Mouse
positive regulation of gtpase activityGO:00435471660.013
regulation of small gtpase mediated signal transductionGO:00510561560.013
positive regulation of transferase activityGO:00513472270.013
neuronal action potentialGO:001922890.013
neuroblast proliferationGO:000740540.013
associative learningGO:000830610.013
positive regulation of programmed cell deathGO:00430682490.013
heart developmentGO:0007507950.013
dephosphorylationGO:00163112090.013
taxisGO:00423301570.013
organelle localizationGO:0051640840.013
protein localization to membraneGO:00726571600.013
Yeast
organophosphate biosynthetic processGO:00904071630.013
positive regulation of reactive oxygen species biosynthetic processGO:190342820.013
response to growth factorGO:00708482050.013
signal transduction by phosphorylationGO:00230142970.013
regulation of mapk cascadeGO:00434082620.013
stem cell divisionGO:001714520.012
regulation of protein depolymerizationGO:1901879220.012
regulation of sequence specific dna binding transcription factor activityGO:00510902110.012
proteasomal protein catabolic processGO:00104981760.012
rna splicingGO:00083801310.012
copulationGO:000762010.012
ameboidal type cell migrationGO:00016671350.012
negative regulation of transcription from rna polymerase ii promoterGO:00001222810.012
long term memoryGO:000761620.012
reproductionGO:0000003630.012
regenerationGO:003109940.012
response to fungusGO:000962040.012
negative regulation of transferase activityGO:00513481240.012
sex differentiationGO:0007548450.012
metencephalon developmentGO:002203720.012
ras protein signal transductionGO:0007265730.012
regulation of kinase activityGO:00435493140.012
determination of adult lifespanGO:000834020.012
rna processingGO:00063962550.012
single organism reproductive processGO:0044702980.012
regulation of growthGO:00400081650.012
positive regulation of immune responseGO:00507781590.012
cell fate determinationGO:000170930.012
regulation of transferase activityGO:00513383550.012
spermatid developmentGO:000728640.012
convergent extension involved in gastrulationGO:006002710.012
somatic muscle developmentGO:000752510.012
regulation of cellular component sizeGO:0032535820.012
chemotaxisGO:00069351570.012
inseminationGO:000732010.012
tissue regenerationGO:004224630.012
positive regulation of protein complex assemblyGO:0031334860.012
muscle cell cellular homeostasisGO:004671630.011
Mouse
neurological system processGO:00508771630.011
positive regulation of atpase activityGO:0032781190.011
inner ear morphogenesisGO:004247240.011
stress activated protein kinase signaling cascadeGO:0031098940.011
protein processingGO:00164852260.011
sleepGO:003043120.011
response to hormoneGO:00097251750.011
regulation of protein processingGO:00706131500.011
cell cycle phase transitionGO:00447701730.011
regulation of protein targetingGO:1903533910.011
multicellular organismal agingGO:001025930.011
blastoderm segmentationGO:000735020.011
regulation of ras protein signal transductionGO:00465781550.011
epithelial cell proliferationGO:00506731280.011
protein targetingGO:00066051870.011
positive regulation of cell proliferationGO:00082843010.011
regulation of response to external stimulusGO:00321012220.011
organ formationGO:004864530.011
cellular response to abiotic stimulusGO:00712141170.011
glycoprotein metabolic processGO:00091001100.011
cardiac muscle tissue developmentGO:0048738390.011
nucleus localizationGO:005164710.011
positive regulation of protein transportGO:00512221350.011
response to metal ionGO:0010038840.011
multicellular organismal response to stressGO:003355510.011
positive regulation of cellular amine metabolic processGO:003324070.011
regulation of cell developmentGO:00602841610.011
Human
lipid metabolic processGO:00066293810.011
protein modification by small protein conjugationGO:00324463420.011
regulation of ras gtpase activityGO:00323181280.011
regulation of muscle system processGO:0090257530.011
regulation of reactive oxygen species biosynthetic processGO:190342630.011
regulation of protein transportGO:00512232130.011
defense responseGO:00069523150.011
developmental process involved in reproductionGO:0003006660.011
cellular response to cytokine stimulusGO:00713451810.011
negative regulation of protein metabolic processGO:00512483910.010
regulation of actin filament lengthGO:0030832560.010
protein import into nucleusGO:00066061040.010
regulation of cytokine productionGO:00018172320.010
action potentialGO:0001508340.010
regulation of phosphatase activityGO:0010921810.010
regulation of actin cytoskeleton organizationGO:00329561160.010
peptidyl tyrosine phosphorylationGO:00181081700.010
cardiac muscle contractionGO:0060048340.010
response to organic cyclic compoundGO:00140702040.010
t cell differentiation in thymusGO:003307740.010
lipid biosynthetic processGO:00086101770.010
protein oligomerizationGO:00512591730.010
cellular response to acid chemicalGO:0071229440.010
regulation of nucleocytoplasmic transportGO:0046822980.010
response to inorganic substanceGO:00100351270.010
ion transmembrane transportGO:00342203380.010
tripartite regional subdivisionGO:000735120.010
regulation of neural precursor cell proliferationGO:200017740.010
mrna metabolic processGO:00160711750.010
small molecule catabolic processGO:0044282920.010
regulation of apoptotic signaling pathwayGO:20012331750.010
negative regulation of developmental processGO:00510932470.010
positive regulation of meiotic cell cycleGO:005144620.010
neurotransmitter secretionGO:000726940.010
glycoprotein biosynthetic processGO:0009101910.010
regulation of camp metabolic processGO:0030814520.010
positive regulation of gliogenesisGO:001401540.010
positive regulation of gtp catabolic processGO:00331261660.010

CFL2 disease predictions

DiseaseDO term IDSizeProbabilityFunc Analog Org
nervous system diseaseDOID:8634310.399
sensory system diseaseDOID:00501552030.399
auditory system diseaseDOID:2742530.390
nonsyndromic deafnessDOID:0050563500.390
central nervous system diseaseDOID:3311860.026
muscular diseaseDOID:00800001140.025
musculoskeletal system diseaseDOID:172230.025
muscle tissue diseaseDOID:661130.025
neurodegenerative diseaseDOID:12891020.020
brain diseaseDOID:936730.017
myopathyDOID:4231040.016
disease of metabolismDOID:00146672950.015
disease of cellular proliferationDOID:145661740.014
eye and adnexa diseaseDOID:14921500.014
eye diseaseDOID:56141490.014
epilepsy syndromeDOID:1826410.013
muscular dystrophyDOID:9884510.012
neonatal period electroclinical syndromeDOID:0050702190.011
electroclinical syndromeDOID:0050701320.011
inherited metabolic disorderDOID:6552420.011
connective tissue diseaseDOID:651090.011
bone diseaseDOID:0080001880.011
retinal diseaseDOID:56791180.010