IMP: Integrative Multi-species Prediction

Homo sapiens

0 known processes

TIMM23

translocase of inner mitochondrial membrane 23 homolog (yeast) and translocase of inner mitochondrial membrane 23 homolog (yeast)

(Aliases: FLJ40725,FLJ57459,MGC71995,FLJ56773,MGC87383,TIM23,MGC22767,FLJ79448)

HPRD: 16089
Entrez: 100287932
Ensembl: ENSG00000138297
HGNC: 17312
MIM: 605034
UniProtKB: O14925

Process Predictions
Disease Predictions

TIMM23 biological process predictions

Show only novel predictionsHighlight processes of functional analogs

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Biological process	GO term ID	Process size	Probability	Func Analog Org
mitochondrial transport	GO:0006839	60	0.753	Yeast
post embryonic development	GO:0009791	2	0.578
intracellular protein transmembrane import	GO:0044743	23	0.563	Yeast
transmembrane transport	GO:0055085	399	0.466	Yeast
vesicle mediated transport	GO:0016192	371	0.354
mitochondrion organization	GO:0007005	156	0.327	Yeast
cytoplasmic transport	GO:0016482	379	0.325	Yeast
receptor mediated endocytosis	GO:0006898	84	0.178
single organism membrane organization	GO:0044802	268	0.162
protein localization to mitochondrion	GO:0070585	25	0.161	Yeast
endocytosis	GO:0006897	159	0.154
protein import into mitochondrial matrix	GO:0030150	1	0.142	Yeast
intracellular protein transmembrane transport	GO:0065002	24	0.136	Yeast
embryo development	GO:0009790	123	0.113	Worm
establishment of protein localization to organelle	GO:0072594	172	0.106	Yeast
intracellular protein transport	GO:0006886	270	0.103	Yeast
phototransduction	GO:0007602	3	0.102
embryo development ending in birth or egg hatching	GO:0009792	34	0.100	Worm
anion transport	GO:0006820	161	0.097
cellular macromolecular complex assembly	GO:0034622	324	0.094
mitochondrial membrane organization	GO:0007006	40	0.089
single organism cellular localization	GO:1902580	332	0.087	Yeast
positive regulation of programmed cell death	GO:0043068	249	0.070
detection of stimulus	GO:0051606	85	0.067
positive regulation of organelle organization	GO:0010638	195	0.065
protein import	GO:0017038	130	0.061	Yeast
multicellular organismal aging	GO:0010259	3	0.056
spermatid development	GO:0007286	4	0.055
membrane organization	GO:0061024	292	0.053
purine ribonucleoside metabolic process	GO:0046128	437	0.049
protein targeting	GO:0006605	187	0.042	Yeast
epithelium development	GO:0060429	227	0.041
apoptotic mitochondrial changes	GO:0008637	57	0.040
protein localization to organelle	GO:0033365	280	0.037	Yeast
positive regulation of mitochondrion organization	GO:0010822	30	0.037
nitrogen compound transport	GO:0071705	191	0.036
negative regulation of apoptotic process	GO:0043066	316	0.036
cellular macromolecule catabolic process	GO:0044265	380	0.035
establishment of protein localization to mitochondrion	GO:0072655	22	0.033	Yeast
nuclear migration	GO:0007097	1	0.032
reproductive structure development	GO:0048608	55	0.032	Worm
nucleoside triphosphate metabolic process	GO:0009141	422	0.031
purine ribonucleoside monophosphate metabolic process	GO:0009167	186	0.031
nucleobase containing compound transport	GO:0015931	51	0.029
cellular protein complex assembly	GO:0043623	188	0.029
protein transmembrane transport	GO:0071806	25	0.029	Yeast
spermatid differentiation	GO:0048515	4	0.029
positive regulation of cellular component organization	GO:0051130	376	0.029
protein maturation	GO:0051604	233	0.028
reproduction	GO:0000003	63	0.027	Worm
regulation of protein maturation	GO:1903317	150	0.025
determination of adult lifespan	GO:0008340	2	0.024
negative regulation of cell death	GO:0060548	345	0.024
protein targeting to mitochondrion	GO:0006626	19	0.023	Yeast
regulation of apoptotic signaling pathway	GO:2001233	175	0.022
ion transmembrane transport	GO:0034220	338	0.022
regeneration	GO:0031099	4	0.022
nucleus localization	GO:0051647	1	0.022
locomotory behavior	GO:0007626	1	0.022
organophosphate catabolic process	GO:0046434	430	0.021
single organism reproductive process	GO:0044702	98	0.021	Worm
tissue regeneration	GO:0042246	3	0.020
regulation of peptidase activity	GO:0052547	180	0.019
purine ribonucleoside triphosphate metabolic process	GO:0009205	411	0.019
dna catabolic process	GO:0006308	49	0.019
oogenesis	GO:0048477	2	0.019
epithelial cell differentiation	GO:0030855	141	0.019
regulation of protein processing	GO:0070613	150	0.019
purine nucleotide catabolic process	GO:0006195	405	0.018
positive regulation of apoptotic process	GO:0043065	246	0.018
small molecule biosynthetic process	GO:0044283	157	0.018
negative regulation of catalytic activity	GO:0043086	335	0.018
positive regulation of cell death	GO:0010942	263	0.017
protein localization to membrane	GO:0072657	160	0.017
nucleoside triphosphate catabolic process	GO:0009143	394	0.017
blastoderm segmentation	GO:0007350	2	0.017
regulation of cell motility	GO:2000145	299	0.017
rna interference	GO:0016246	4	0.017
growth	GO:0040007	202	0.017
regulation of cell adhesion	GO:0030155	166	0.016
negative regulation of programmed cell death	GO:0043069	321	0.016
purine nucleoside triphosphate metabolic process	GO:0009144	412	0.016
response to oxidative stress	GO:0006979	121	0.015
female gamete generation	GO:0007292	2	0.015
regulation of proteolysis	GO:0030162	293	0.015
amine metabolic process	GO:0009308	44	0.015
ribonucleoside triphosphate metabolic process	GO:0009199	412	0.015
nucleoside phosphate catabolic process	GO:1901292	412	0.015
regulation of ion transport	GO:0043269	189	0.014
positive regulation of developmental process	GO:0051094	314	0.014
purine ribonucleoside catabolic process	GO:0046130	398	0.014
negative regulation of intracellular signal transduction	GO:1902532	183	0.014
apoptotic signaling pathway	GO:0097190	268	0.014
ribonucleoside triphosphate catabolic process	GO:0009203	391	0.014
proteolysis involved in cellular protein catabolic process	GO:0051603	244	0.014
nucleocytoplasmic transport	GO:0006913	176	0.014
negative regulation of catabolic process	GO:0009895	104	0.014
purine ribonucleoside triphosphate catabolic process	GO:0009207	391	0.014
negative regulation of protein processing	GO:0010955	142	0.013
negative regulation of organelle organization	GO:0010639	126	0.013
ribonucleoprotein complex assembly	GO:0022618	78	0.013
response to virus	GO:0009615	126	0.013
detection of abiotic stimulus	GO:0009582	15	0.013
regulation of dna metabolic process	GO:0051052	153	0.013
cell growth	GO:0016049	160	0.013
regulation of endopeptidase activity	GO:0052548	170	0.013
reproductive system development	GO:0061458	56	0.013	Worm
mitotic cell cycle	GO:0000278	326	0.012
establishment of organelle localization	GO:0051656	59	0.012
regulation of innate immune response	GO:0045088	97	0.012
regulation of cellular component biogenesis	GO:0044087	281	0.012
immune response	GO:0006955	307	0.012
protein processing	GO:0016485	226	0.012
negative regulation of cellular component organization	GO:0051129	235	0.012
reproductive process	GO:0022414	106	0.012	Worm
regulation of mitochondrial membrane permeability	GO:0046902	25	0.012
regulation of immune response	GO:0050776	201	0.012
adult locomotory behavior	GO:0008344	1	0.012
defense response to other organism	GO:0098542	129	0.012
ribonucleoside catabolic process	GO:0042454	406	0.011
nucleoside catabolic process	GO:0009164	408	0.011
regulation of mitochondrial membrane permeability involved in apoptotic process	GO:1902108	18	0.011
nucleotide catabolic process	GO:0009166	408	0.011
multi organism reproductive process	GO:0044703	54	0.011
segmentation	GO:0035282	4	0.011
multicellular organism reproduction	GO:0032504	42	0.011
organic anion transport	GO:0015711	103	0.011
establishment of nucleus localization	GO:0040023	1	0.011
anterior posterior axis specification	GO:0009948	2	0.011
negative regulation of transcription from rna polymerase ii promoter	GO:0000122	281	0.011
regulation of transmembrane transport	GO:0034762	139	0.011
secretion by cell	GO:0032940	226	0.011
dna replication	GO:0006260	116	0.011
negative regulation of hydrolase activity	GO:0051346	182	0.011
atp metabolic process	GO:0046034	176	0.011
regulation of mitochondrion organization	GO:0010821	54	0.011
nucleic acid phosphodiester bond hydrolysis	GO:0090305	102	0.011
regulation of cell cycle	GO:0051726	393	0.010

TIMM23 disease predictions

Disease	DO term ID	Size	Probability
sensory system disease	DOID:0050155	203	0.053
nervous system disease	DOID:863	431	0.053
disease of cellular proliferation	DOID:14566	174	0.028
organ system cancer	DOID:0050686	164	0.028
cancer	DOID:162	167	0.028
disease of metabolism	DOID:0014667	295	0.014

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