Homo sapiens

49 known processes

CRYAA

crystallin, alpha A

(Aliases: HSPB4,CRYA1)

CRYAA biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
sensory perception of light stimulusGO:0050953351.000
visual perceptionGO:0007601270.983
cellular response to oxidative stressGO:0034599850.810
sensory perceptionGO:00076001030.711
cellular response to reactive oxygen speciesGO:0034614500.580
cellular response to oxygen containing compoundGO:19017012760.509
neurological system processGO:00508771630.499
response to reactive oxygen speciesGO:0000302610.396
response to oxygen containing compoundGO:19017003690.310
system processGO:00030083490.301
negative regulation of reactive oxygen species metabolic processGO:2000378110.199
response to organic cyclic compoundGO:00140702040.189
response to estradiolGO:0032355230.189
regulation of reactive oxygen species metabolic processGO:2000377410.181
cellular ketone metabolic processGO:0042180800.176
response to oxidative stressGO:00069791210.156
Fly
mapk cascadeGO:00001652880.122
ion transmembrane transportGO:00342203380.120
camera type eye developmentGO:0043010250.102
protein foldingGO:0006457380.095
protein oligomerizationGO:00512591730.094
anion transportGO:00068201610.093
urate transportGO:001574730.091
determination of adult lifespanGO:000834020.089
Fly
transmembrane transportGO:00550853990.079
enzyme linked receptor protein signaling pathwayGO:00071673030.078
protein homooligomerizationGO:00512601000.077
alpha ketoglutarate transportGO:001574210.075
ras protein signal transductionGO:0007265730.073
cellular amino acid metabolic processGO:00065201160.072
vasculature developmentGO:00019441810.071
divalent metal ion transportGO:00708381520.065
eye developmentGO:0001654420.065
cellular amine metabolic processGO:0044106410.064
positive regulation of cellular amine metabolic processGO:003324070.063
renal tubular secretionGO:009725410.063
regulation of protein kinase activityGO:00458592890.061
cation transportGO:00068123310.059
multicellular organismal agingGO:001025930.053
Fly
negative regulation of cell deathGO:00605483450.051
microtubule based processGO:00070172100.050
metal ion homeostasisGO:00550651690.050
ion homeostasisGO:00508012300.050
cellular chemical homeostasisGO:00550821800.048
wound healingGO:00420601150.048
negative regulation of protein metabolic processGO:00512483910.047
negative regulation of phosphate metabolic processGO:00459362670.047
response to hydrogen peroxideGO:0042542400.046
regulation of cellular amine metabolic processGO:0033238110.046
monocarboxylic acid metabolic processGO:00327871850.044
negative regulation of apoptotic processGO:00430663160.044
negative regulation of cellular protein metabolic processGO:00322693530.043
locomotory behaviorGO:000762610.043
positive regulation of cellular amino acid metabolic processGO:004576430.043
cell growthGO:00160491600.042
amine metabolic processGO:0009308440.040
transmembrane receptor protein tyrosine kinase signaling pathwayGO:00071691810.039
sensory organ developmentGO:0007423520.039
regulation of cellular amino acid metabolic processGO:000652160.038
microtubule polymerization or depolymerizationGO:0031109370.038
organonitrogen compound biosynthetic processGO:19015662000.038
regulation of cellular response to stressGO:00801352440.038
chemical homeostasisGO:00488783060.037
purine nucleotide biosynthetic processGO:0006164840.037
regulation of secretionGO:00510461940.036
purine nucleoside triphosphate catabolic processGO:00091463920.036
nitrogen compound transportGO:00717051910.035
regulation of cellular ketone metabolic processGO:0010565500.035
regulation of cellular component movementGO:00512703340.035
purine ribonucleotide biosynthetic processGO:0009152790.035
regulation of ion transmembrane transportGO:00347651320.035
response to abiotic stimulusGO:00096283360.034
Human Fly
positive regulation of phosphorylationGO:00423273940.034
negative regulation of growthGO:0045926970.034
negative regulation of intracellular signal transductionGO:19025321830.033
small gtpase mediated signal transductionGO:0007264780.033
response to inorganic substanceGO:00100351270.033
regulation of secretion by cellGO:19035301770.033
positive regulation of hydrolase activityGO:00513453310.032
positive regulation of cell migrationGO:00303351720.032
purine ribonucleoside catabolic processGO:00461303980.032
response to drugGO:0042493810.031
organic hydroxy compound transportGO:0015850630.031
regulation of oxidative stress induced cell deathGO:1903201240.031
regulation of intracellular transportGO:00323861950.031
cytosolic calcium ion homeostasisGO:0051480890.031
regulation of small gtpase mediated signal transductionGO:00510561560.030
tissue homeostasisGO:0001894630.030
cellular homeostasisGO:00197251960.030
ribonucleoside triphosphate metabolic processGO:00091994120.030
regulation of kinase activityGO:00435493140.030
homeostasis of number of cells in a free living populationGO:004887410.030
cellular ion homeostasisGO:00068731680.030
regulation of apoptotic signaling pathwayGO:20012331750.030
secretion by cellGO:00329402260.029
positive regulation of purine nucleotide metabolic processGO:19005442270.029
one carbon compound transportGO:001975540.028
nucleoside phosphate biosynthetic processGO:19012931090.028
purine containing compound biosynthetic processGO:0072522880.028
response to lipidGO:00339932060.028
positive regulation of nucleotide metabolic processGO:00459812300.027
response to organonitrogen compoundGO:00102431560.027
inorganic cation transmembrane transportGO:00986621940.027
nucleoside catabolic processGO:00091644080.027
response to external biotic stimulusGO:00432072610.027
Fly
coagulationGO:0050817780.027
negative regulation of catalytic activityGO:00430863350.027
cyclic nucleotide metabolic processGO:0009187820.027
ribose phosphate biosynthetic processGO:0046390820.026
metal ion transportGO:00300012720.026
purine ribonucleoside metabolic processGO:00461284370.026
carnitine transmembrane transportGO:190260330.026
ribonucleotide biosynthetic processGO:0009260810.026
organophosphate catabolic processGO:00464344300.025
cyclic purine nucleotide metabolic processGO:0052652600.025
stress activated protein kinase signaling cascadeGO:0031098940.025
secretionGO:00469032540.025
regulation of proteolysisGO:00301622930.025
purine nucleoside triphosphate metabolic processGO:00091444120.025
biological adhesionGO:00226103310.025
protein processingGO:00164852260.025
regulation of hormone levelsGO:00108171250.025
g protein coupled receptor signaling pathway coupled to cyclic nucleotide second messengerGO:0007187430.025
forebrain regionalizationGO:002187130.024
regulation of growthGO:00400081650.024
carbohydrate derivative biosynthetic processGO:19011372070.024
negative regulation of cellular amino acid metabolic processGO:004576320.024
regulation of nucleotide metabolic processGO:00061402690.024
nucleotide biosynthetic processGO:00091651090.024
cellular calcium ion homeostasisGO:00068741170.024
regulation of i kappab kinase nf kappab signalingGO:00431221620.024
positive regulation of cellular component movementGO:00512721810.024
sulfur compound metabolic processGO:00067901010.024
female gamete generationGO:000729220.024
ribonucleoside triphosphate catabolic processGO:00092033910.024
ribonucleoside catabolic processGO:00424544060.024
regulation of nucleotide catabolic processGO:00308112050.024
calcium ion homeostasisGO:00550741220.023
purine nucleoside catabolic processGO:00061523980.023
ribonucleoside monophosphate metabolic processGO:00091611870.023
cellular response to endogenous stimulusGO:00714953360.023
response to woundingGO:00096111680.023
purine containing compound catabolic processGO:00725234110.023
growthGO:00400072020.023
regulation of cell cycleGO:00517263930.023
negative regulation of phosphorus metabolic processGO:00105632670.023
regulation of protein secretionGO:0050708860.023
taxisGO:00423301570.023
defense responseGO:00069523150.023
Fly
regulation of anatomical structure sizeGO:00900661010.023
regulation of cysteine type endopeptidase activityGO:20001161270.023
positive regulation of apoptotic processGO:00430652460.022
regulation of cell developmentGO:00602841610.022
response to virusGO:00096151260.022
negative regulation of programmed cell deathGO:00430693210.022
nucleoside triphosphate metabolic processGO:00091414220.022
negative regulation of phosphorylationGO:00423261740.022
cellular response to organonitrogen compoundGO:00714171240.022
positive regulation of cell deathGO:00109422630.022
cation transmembrane transportGO:00986552380.022
signal transduction by phosphorylationGO:00230142970.022
cyclic nucleotide biosynthetic processGO:0009190610.022
positive regulation of programmed cell deathGO:00430682490.021
short chain fatty acid importGO:001591310.021
regulation of peptidase activityGO:00525471800.021
regulation of transferase activityGO:00513383550.021
small molecule biosynthetic processGO:00442831570.021
neuromuscular junction developmentGO:000752830.021
reactive oxygen species metabolic processGO:0072593750.021
epithelium developmentGO:00604292270.021
nucleotide catabolic processGO:00091664080.021
purine nucleoside monophosphate catabolic processGO:00091281580.021
positive regulation of mapk cascadeGO:00434101900.020
blood coagulationGO:0007596760.020
positive regulation of interleukin 1 beta productionGO:0032731130.020
post embryonic developmentGO:000979120.020
Fly
negative regulation of cell growthGO:0030308830.020
negative regulation of multicellular organismal processGO:00512413170.020
oogenesisGO:004847720.020
negative regulation of hydrolase activityGO:00513461820.020
positive regulation of nucleotide catabolic processGO:00308131850.020
organophosphate biosynthetic processGO:00904071630.020
organic anion transportGO:00157111030.020
cytoplasmic transportGO:00164823790.020
angiogenesisGO:00015251470.020
purine ribonucleoside triphosphate metabolic processGO:00092054110.020
divalent inorganic cation homeostasisGO:00725071360.020
inorganic ion transmembrane transportGO:00986602310.020
symbiosis encompassing mutualism through parasitismGO:00444031560.019
cellular macromolecule catabolic processGO:00442653800.019
nucleoside monophosphate metabolic processGO:00091231910.019
nucleoside triphosphate catabolic processGO:00091433940.019
cell activationGO:00017752130.019
negative regulation of cellular amine metabolic processGO:003323930.019
positive regulation of locomotionGO:00400171860.018
defense response to other organismGO:00985421290.018
Fly
carbohydrate metabolic processGO:00059752070.018
g protein coupled receptor signaling pathwayGO:00071862070.018
cardiovascular system developmentGO:00723582620.018
immune responseGO:00069553070.018
regulation of intrinsic apoptotic signaling pathwayGO:2001242720.018
cellular lipid metabolic processGO:00442553030.018
positive regulation of nucleoside metabolic processGO:00459791860.018
cellular cation homeostasisGO:00300031630.018
cellular response to radiationGO:0071478650.018
Human
positive regulation of angiogenesisGO:0045766510.018
rho protein signal transductionGO:0007266260.018
stress activated mapk cascadeGO:0051403930.018
mitotic cell cycleGO:00002783260.018
response to biotic stimulusGO:00096072760.018
Fly
microtubule cytoskeleton organizationGO:00002261760.017
regulation of nucleoside metabolic processGO:00091182090.017
regulation of protein maturationGO:19033171500.017
cellular metal ion homeostasisGO:00068751460.017
protein catabolic processGO:00301633250.017
response to axon injuryGO:004867810.017
positive regulation of cellular catabolic processGO:00313312840.017
cytokine biosynthetic processGO:0042089370.017
regulation of cell growthGO:00015581350.017
intrinsic apoptotic signaling pathwayGO:00971931270.017
regulation of protein localizationGO:00328802960.017
glycosyl compound catabolic processGO:19016584130.017
regulation of cellular component biogenesisGO:00440872810.017
memoryGO:000761330.017
regulation of immune responseGO:00507762010.017
reactive nitrogen species metabolic processGO:200105730.016
protein maturationGO:00516042330.016
negative regulation of developmental processGO:00510932470.016
epidermis morphogenesisGO:004873030.016
positive regulation of cellular component biogenesisGO:00440891580.016
response to hormoneGO:00097251750.016
lipid transportGO:0006869900.016
single organismal cell cell adhesionGO:00163371480.016
purine ribonucleoside triphosphate catabolic processGO:00092073910.016
monovalent inorganic cation transportGO:00156721280.016
interspecies interaction between organismsGO:00444191560.016
regulation of stress activated mapk cascadeGO:0032872840.016
spinal cord developmentGO:002151040.016
cation homeostasisGO:00550801890.016
protein localization to organelleGO:00333652800.015
negative regulation of protein modification processGO:00314002000.015
regulation of intestinal epithelial structure maintenanceGO:006073010.015
segmentationGO:003528240.015
maintenance of locationGO:00512351120.015
gtp metabolic processGO:00460392390.015
positive regulation of intestinal epithelial structure maintenanceGO:006073110.015
gtp catabolic processGO:00061842370.015
negative regulation of cell differentiationGO:00455961710.015
positive regulation of insulin like growth factor receptor signaling pathwayGO:004356840.015
spermatid differentiationGO:004851540.015
negative regulation of protein kinase activityGO:0006469980.015
cell projection organizationGO:00300302520.015
negative regulation of apoptotic signaling pathwayGO:2001234970.015
regulation of leukocyte activationGO:00026941150.015
positive regulation of proteolysisGO:00458621420.015
innate immune responseGO:00450871780.015
regulation of endopeptidase activityGO:00525481700.015
divalent inorganic cation transportGO:00725111580.015
cellular protein catabolic processGO:00442572610.015
multi organism cellular processGO:00447641560.015
positive regulation of organelle organizationGO:00106381950.015
regulation of cysteine type endopeptidase activity involved in apoptotic processGO:00432811160.015
sequestering of metal ionGO:0051238240.015
neuron fate commitmentGO:004866320.015
regulation of purine nucleotide metabolic processGO:19005422640.015
lipid metabolic processGO:00066293810.015
peripheral nervous system developmentGO:000742220.015
regulation of wound healingGO:0061041560.015
cellular divalent inorganic cation homeostasisGO:00725031280.015
negative regulation of cellular component organizationGO:00511292350.014
positive regulation of epithelial cell proliferation involved in wound healingGO:006005430.014
regulation of interleukin 1 beta productionGO:0032651180.014
developmental programmed cell deathGO:001062330.014
organic acid transportGO:0015849650.014
quorum sensing involved in interaction with hostGO:005210610.014
response to radiationGO:00093141510.014
Human
oxidation reduction processGO:00551143960.014
hormone transportGO:0009914680.014
positive regulation of cytoskeleton organizationGO:0051495830.014
carboxylic acid transportGO:0046942630.014
regulation of metal ion transportGO:00109591200.014
regulation of establishment of protein localizationGO:00702012420.014
cell morphogenesisGO:00009022960.014
cellular response to lipidGO:00713961270.014
purine ribonucleoside monophosphate metabolic processGO:00091671860.014
adult locomotory behaviorGO:000834410.014
regulation of purine nucleotide catabolic processGO:00331212050.014
retina homeostasisGO:0001895420.014
cellular response to dna damage stimulusGO:00069743790.014
protein secretionGO:0009306980.014
regulation of cell differentiationGO:00455953930.014
response to steroid hormoneGO:0048545800.014
positive regulation of catabolic processGO:00098963100.014
regenerationGO:003109940.014
posttranscriptional regulation of gene expressionGO:00106082130.014
chemotaxisGO:00069351570.013
negative regulation of cellular response to oxidative stressGO:1900408180.013
blood vessel morphogenesisGO:00485141620.013
defense response to bacteriumGO:0042742630.013
Fly
gas transportGO:001566930.013
alpha amino acid metabolic processGO:1901605720.013
purine ribonucleotide catabolic processGO:00091544040.013
positive regulation of protein kinase activityGO:00458601900.013
ribonucleotide catabolic processGO:00092614050.013
regulation of transmembrane transporter activityGO:0022898740.013
adenylate cyclase modulating g protein coupled receptor signaling pathwayGO:0007188430.013
reactive oxygen species biosynthetic processGO:190340940.013
positive regulation of glucocorticoid metabolic processGO:003194510.013
regulation of defense responseGO:00313471540.013
negative regulation of protein processingGO:00109551420.013
negative regulation of transferase activityGO:00513481240.013
anterior posterior axis specificationGO:000994820.013
response to estrogenGO:0043627470.013
positive regulation of cyclic nucleotide biosynthetic processGO:0030804380.013
negative regulation of voltage gated calcium channel activityGO:190138640.013
lipid localizationGO:00108761060.013
small molecule catabolic processGO:0044282920.013
negative regulation of transportGO:00510511760.013
regulation of multi organism processGO:00439001570.013
long term memoryGO:000761620.013
guanosine containing compound metabolic processGO:19010682440.013
response to nitrogen compoundGO:19016981840.013
purine nucleotide catabolic processGO:00061954050.012
positive regulation of secretionGO:00510471160.012
cellular macromolecular complex assemblyGO:00346223240.012
guanosine containing compound catabolic processGO:19010692390.012
anion transmembrane transportGO:0098656760.012
nucleoside phosphate catabolic processGO:19012924120.012
cellular amide metabolic processGO:0043603690.012
cell divisionGO:00513011680.012
photoreceptor cell differentiationGO:004653020.012
thymus developmentGO:004853830.012
cytokine productionGO:00018162470.012
cell developmentGO:00484683280.012
single organism membrane organizationGO:00448022680.012
oocyte differentiationGO:000999420.012
lens development in camera type eyeGO:000208820.012
atp metabolic processGO:00460341760.012
response to cytokineGO:00340972320.012
cellular response to cytokine stimulusGO:00713451810.012
regulation of cytoskeleton organizationGO:00514931770.012
associative learningGO:000830610.012
calcium ion transportGO:00068161470.012
regulation of ras protein signal transductionGO:00465781550.012
regulation of wnt signaling pathwayGO:00301111230.012
mitochondrion organizationGO:00070051560.012
axis elongationGO:000340140.012
embryonic hemopoiesisGO:003516240.012
response to activityGO:001482300.012
regulation of protein catabolic processGO:00421761550.012
negative regulation of protein maturationGO:19033181420.012
regulation of cell cycle processGO:00105642660.012
salivary gland morphogenesisGO:000743540.012
sequestering of calcium ionGO:0051208170.012
regulation of dna metabolic processGO:00510521530.012
negative regulation of response to oxidative stressGO:1902883180.012
positive regulation of purine nucleotide catabolic processGO:00331231850.012
negative regulation of cell cycleGO:00457861930.012
compound eye developmentGO:004874910.012
response to corticotropin releasing hormoneGO:004343510.011
positive regulation of cysteine type endopeptidase activityGO:2001056790.011
cell chemotaxisGO:00603261120.011
positive regulation of transferase activityGO:00513472270.011
regulation of mitotic cell cycleGO:00073461890.011
blastoderm segmentationGO:000735020.011
positive regulation of cytokine productionGO:00018191670.011
oocyte developmentGO:004859910.011
positive regulation of peptidase activityGO:0010952880.011
inflammatory responseGO:0006954790.011
hormone secretionGO:0046879650.011
regulation of cytoplasmic transportGO:19036491490.011
cell differentiation in spinal cordGO:002151510.011
sex determinationGO:000753030.011
regulation of actin filament based processGO:00329701410.011
endomembrane system organizationGO:00102561960.011
renal system processGO:0003014250.011
matingGO:000761810.011
regulation of actin cytoskeleton organizationGO:00329561160.011
cellular response to abiotic stimulusGO:00712141170.011
Human
positive regulation of cytoplasmic transportGO:1903651820.011
response to salt stressGO:000965130.011
regulation of protein transportGO:00512232130.011
epithelium migrationGO:00901321190.011
positive regulation of transportGO:00510503360.011
cell death in response to oxidative stressGO:0036473290.011
regulation of gtp catabolic processGO:00331241800.011
immune system developmentGO:00025201950.011
syncytium formation by plasma membrane fusionGO:000076820.011
proteolysis involved in cellular protein catabolic processGO:00516032440.011
negative regulation of kinase activityGO:00336731060.011
positive regulation of protein phosphorylationGO:00019343130.011
regulation of gtpase activityGO:00430871800.011
regulation of vesicle mediated transportGO:00606271300.011
negative regulation of protein phosphorylationGO:00019331400.011
regulation of cytokine productionGO:00018172320.011
positive regulation of secretion by cellGO:19035321080.011
atp catabolic processGO:00062001570.011
actin filament organizationGO:00070151280.011
purine ribonucleoside monophosphate catabolic processGO:00091691580.010
negative regulation of response to external stimulusGO:0032102830.010
positive regulation of immune responseGO:00507781590.010
positive regulation of cellular component organizationGO:00511303760.010
regulation of cell adhesionGO:00301551660.010
alcohol metabolic processGO:00060661140.010
activation of immune responseGO:00022531140.010
regulation of sequence specific dna binding transcription factor activityGO:00510902110.010
glycerolipid metabolic processGO:00464861070.010
cellular response to nitrogen compoundGO:19016991440.010
ubiquitin dependent protein catabolic processGO:00065112060.010
phosphatidylinositol 3 kinase signalingGO:0014065480.010
regulation of protein complex assemblyGO:00432541470.010
vesicle mediated transportGO:00161923710.010
positive regulation of digestive system processGO:006045620.010
lipid biosynthetic processGO:00086101770.010
quorum sensingGO:000937210.010
wnt signaling pathwayGO:00160551560.010
endothelial cell migrationGO:0043542860.010
specification of organ identityGO:001009230.010
negative regulation of transcription from rna polymerase ii promoterGO:00001222810.010
sensory perception of painGO:001923340.010
regulation of homeostatic processGO:00328441210.010
nuclear transportGO:00511691790.010
cell proliferation in forebrainGO:002184610.010
protein targetingGO:00066051870.010

CRYAA disease predictions

DiseaseDO term IDSizeProbabilityFunc Analog Org
nervous system diseaseDOID:8634310.869
Human
eye and adnexa diseaseDOID:14921500.869
Human
sensory system diseaseDOID:00501552030.869
Human
eye diseaseDOID:56141490.869
Human
cardiovascular system diseaseDOID:12871060.424
Human
musculoskeletal system diseaseDOID:172230.424
Human
cardiomyopathyDOID:0050700500.424
Human
heart diseaseDOID:114680.424
Human
myopathyDOID:4231040.424
Human
muscular diseaseDOID:00800001140.424
Human
muscle tissue diseaseDOID:661130.424
Human
retinal diseaseDOID:56791180.051
night blindnessDOID:8499100.051
central nervous system diseaseDOID:3311860.049
Human
disease of metabolismDOID:00146672950.041
neurodegenerative diseaseDOID:12891020.028
Human
disease of cellular proliferationDOID:145661740.022
cancerDOID:1621670.022
organ system cancerDOID:00506861640.022
intrinsic cardiomyopathyDOID:0060036500.017
Human
dilated cardiomyopathyDOID:12930320.016
Human
connective tissue diseaseDOID:651090.016
bone diseaseDOID:0080001880.016
immune system diseaseDOID:29141550.014
inherited metabolic disorderDOID:6552420.013
retinal degenerationDOID:8466890.013
urinary system diseaseDOID:18400.013
neuromuscular diseaseDOID:440380.012
Human
neuropathyDOID:870520.012
Human
renal tubular transport diseaseDOID:447110.011
kidney diseaseDOID:557360.011
acquired metabolic diseaseDOID:0060158580.011
charcot marie tooth diseaseDOID:10595330.010
Human