Homo sapiens

0 known processes

PLEKHG1

pleckstrin homology domain containing, family G (with RhoGef domain) member 1

(Aliases: FLJ31738,KIAA1209,ARHGEF41)

PLEKHG1 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
post embryonic developmentGO:000979120.069
cellular amine metabolic processGO:0044106410.068
cellular ketone metabolic processGO:0042180800.066
cellular amino acid metabolic processGO:00065201160.064
regulation of cellular amino acid metabolic processGO:000652160.062
regulation of cellular amine metabolic processGO:0033238110.061
amine metabolic processGO:0009308440.060
glycosyl compound catabolic processGO:19016584130.054
regulation of cellular ketone metabolic processGO:0010565500.052
purine containing compound catabolic processGO:00725234110.051
nucleotide catabolic processGO:00091664080.051
positive regulation of cellular amino acid metabolic processGO:004576430.050
purine nucleotide catabolic processGO:00061954050.049
nucleoside catabolic processGO:00091644080.049
purine nucleoside catabolic processGO:00061523980.048
positive regulation of cellular amine metabolic processGO:003324070.047
ribonucleoside triphosphate catabolic processGO:00092033910.047
purine ribonucleotide catabolic processGO:00091544040.045
ribonucleoside triphosphate metabolic processGO:00091994120.045
nucleoside triphosphate catabolic processGO:00091433940.044
purine ribonucleoside triphosphate catabolic processGO:00092073910.044
purine ribonucleoside triphosphate metabolic processGO:00092054110.044
purine ribonucleoside metabolic processGO:00461284370.044
nucleoside phosphate catabolic processGO:19012924120.044
purine nucleoside triphosphate metabolic processGO:00091444120.043
organophosphate catabolic processGO:00464344300.043
ras protein signal transductionGO:0007265730.042
ribonucleoside catabolic processGO:00424544060.042
purine nucleoside triphosphate catabolic processGO:00091463920.042
positive regulation of phosphorylationGO:00423273940.042
multicellular organismal agingGO:001025930.041
nucleoside triphosphate metabolic processGO:00091414220.041
ribonucleotide catabolic processGO:00092614050.040
small gtpase mediated signal transductionGO:0007264780.039
purine ribonucleoside catabolic processGO:00461303980.039
determination of adult lifespanGO:000834020.038
locomotory behaviorGO:000762610.038
actin filament based processGO:00300292240.037
Worm
positive regulation of hydrolase activityGO:00513453310.036
regulation of nucleotide metabolic processGO:00061402690.036
gtp metabolic processGO:00460392390.035
cytoplasmic transportGO:00164823790.035
regulation of locomotionGO:00400123290.035
system processGO:00030083490.034
positive regulation of catabolic processGO:00098963100.034
cellular macromolecule catabolic processGO:00442653800.034
immune responseGO:00069553070.034
vesicle mediated transportGO:00161923710.033
Worm
regulation of purine nucleotide metabolic processGO:19005422640.033
female gamete generationGO:000729220.032
gtp catabolic processGO:00061842370.032
oogenesisGO:004847720.032
regulation of cellular component movementGO:00512703340.032
lipid metabolic processGO:00066293810.032
rho protein signal transductionGO:0007266260.032
positive regulation of cellular catabolic processGO:00313312840.032
protein catabolic processGO:00301633250.031
Worm
regulation of cell differentiationGO:00455953930.031
regulation of cell motilityGO:20001452990.031
positive regulation of cellular component organizationGO:00511303760.031
negative regulation of cellular protein metabolic processGO:00322693530.031
cell adhesionGO:00071553250.031
biological adhesionGO:00226103310.030
negative regulation of catalytic activityGO:00430863350.030
positive regulation of transportGO:00510503360.030
cellular lipid metabolic processGO:00442553030.030
transmembrane transportGO:00550853990.030
segmentationGO:003528240.030
defense responseGO:00069523150.029
mitotic cell cycleGO:00002783260.029
cell developmentGO:00484683280.029
Worm
single organism cellular localizationGO:19025803320.029
negative regulation of protein metabolic processGO:00512483910.029
positive regulation of protein phosphorylationGO:00019343130.029
guanosine containing compound metabolic processGO:19010682440.029
response to oxygen containing compoundGO:19017003690.029
cell morphogenesisGO:00009022960.028
cation transportGO:00068123310.028
regulation of protein localizationGO:00328802960.028
positive regulation of purine nucleotide metabolic processGO:19005442270.028
regulation of cellular component biogenesisGO:00440872810.028
regulation of purine nucleotide catabolic processGO:00331212050.028
regulation of transferase activityGO:00513383550.028
cell projection organizationGO:00300302520.027
regulation of cell migrationGO:00303342890.027
intracellular protein transportGO:00068862700.027
nervous system developmentGO:00073992930.027
regulation of gtp catabolic processGO:00331241800.027
regulation of anatomical structure morphogenesisGO:00226032860.027
guanosine containing compound catabolic processGO:19010692390.026
chemical homeostasisGO:00488783060.026
response to abiotic stimulusGO:00096283360.026
cellular response to dna damage stimulusGO:00069743790.026
regenerationGO:003109940.026
mitotic cell cycle processGO:19030472860.025
neuromuscular junction developmentGO:000752830.025
dephosphorylationGO:00163112090.025
single organism membrane organizationGO:00448022680.025
negative regulation of cell deathGO:00605483450.025
anatomical structure formation involved in morphogenesisGO:00486462840.025
Worm
positive regulation of immune system processGO:00026842830.025
cellular component morphogenesisGO:00329893140.025
Worm
ion transmembrane transportGO:00342203380.025
positive regulation of nucleotide metabolic processGO:00459812300.024
regulation of kinase activityGO:00435493140.024
positive regulation of nucleoside metabolic processGO:00459791860.024
negative regulation of phosphate metabolic processGO:00459362670.024
protein maturationGO:00516042330.024
regulation of cell cycleGO:00517263930.024
memoryGO:000761330.024
positive regulation of nucleotide catabolic processGO:00308131850.024
negative regulation of multicellular organismal processGO:00512413170.024
negative regulation of programmed cell deathGO:00430693210.024
cellular response to endogenous stimulusGO:00714953360.024
protein modification by small protein conjugationGO:00324463420.023
negative regulation of apoptotic processGO:00430663160.023
regulation of proteolysisGO:00301622930.023
negative regulation of phosphorus metabolic processGO:00105632670.023
positive regulation of purine nucleotide catabolic processGO:00331231850.023
metal ion transportGO:00300012720.023
signal transduction by phosphorylationGO:00230142970.023
regulation of nucleotide catabolic processGO:00308112050.023
response to external biotic stimulusGO:00432072610.023
membrane organizationGO:00610242920.023
Worm
response to other organismGO:00517072610.023
negative regulation of cellular amine metabolic processGO:003323930.023
cellular macromolecular complex assemblyGO:00346223240.023
Worm
positive regulation of gtpase activityGO:00435471660.022
regulation of nucleoside metabolic processGO:00091182090.022
positive regulation of gtp catabolic processGO:00331261660.022
regulation of establishment of protein localizationGO:00702012420.022
protein ubiquitinationGO:00165673140.022
cellular protein catabolic processGO:00442572610.022
organonitrogen compound biosynthetic processGO:19015662000.022
carbohydrate derivative biosynthetic processGO:19011372070.022
blastoderm segmentationGO:000735020.022
morphogenesis of embryonic epitheliumGO:001633140.022
positive regulation of transferase activityGO:00513472270.022
mapk cascadeGO:00001652880.022
epithelium developmentGO:00604292270.022
cytokine productionGO:00018162470.022
cellular response to oxygen containing compoundGO:19017012760.022
hindbrain developmentGO:003090230.022
protein localization to organelleGO:00333652800.022
organ formationGO:004864530.022
protein processingGO:00164852260.021
regulation of response to external stimulusGO:00321012220.021
negative regulation of cellular amino acid metabolic processGO:004576320.021
ion homeostasisGO:00508012300.021
anterior posterior axis specificationGO:000994820.021
negative regulation of cellular component organizationGO:00511292350.021
proteolysis involved in cellular protein catabolic processGO:00516032440.021
response to biotic stimulusGO:00096072760.021
regulation of cell cycle processGO:00105642660.021
endomembrane system organizationGO:00102561960.021
regulation of mapk cascadeGO:00434082620.021
regulation of cellular response to stressGO:00801352440.021
inorganic ion transmembrane transportGO:00986602310.021
apoptotic signaling pathwayGO:00971902680.021
positive regulation of cell deathGO:00109422630.021
regulation of protein kinase activityGO:00458592890.021
negative regulation of cell proliferationGO:00082852280.021
secretionGO:00469032540.020
embryonic epithelial tube formationGO:000183840.020
positive regulation of developmental processGO:00510943140.020
regulation of cytokine productionGO:00018172320.020
enzyme linked receptor protein signaling pathwayGO:00071673030.020
positive regulation of cell proliferationGO:00082843010.020
motor neuron axon guidanceGO:000804520.020
circulatory system developmentGO:00723592620.020
carbohydrate metabolic processGO:00059752070.020
adult locomotory behaviorGO:000834410.020
regulation of protein transportGO:00512232130.020
positive regulation of apoptotic processGO:00430652460.020
secretion by cellGO:00329402260.019
cardiovascular system developmentGO:00723582620.019
oxidation reduction processGO:00551143960.019
regulation of gtpase activityGO:00430871800.019
chromatin organizationGO:00063253510.019
regulation of cytoskeleton organizationGO:00514931770.019
wnt signaling pathwayGO:00160551560.019
cation transmembrane transportGO:00986552380.019
negative regulation of protein modification processGO:00314002000.019
positive regulation of programmed cell deathGO:00430682490.019
modification dependent macromolecule catabolic processGO:00436322120.019
microtubule based processGO:00070172100.019
regulation of intracellular transportGO:00323861950.019
ubiquitin dependent protein catabolic processGO:00065112060.019
regulation of ras protein signal transductionGO:00465781550.019
negative regulation of hydrolase activityGO:00513461820.019
small molecule biosynthetic processGO:00442831570.018
innate immune responseGO:00450871780.018
oocyte differentiationGO:000999420.018
oocyte developmentGO:004859910.018
inorganic cation transmembrane transportGO:00986621940.018
single organism cell adhesionGO:00986021790.018
single organism carbohydrate metabolic processGO:00447231930.018
rhythmic behaviorGO:000762220.018
anion transportGO:00068201610.018
regulation of sequence specific dna binding transcription factor activityGO:00510902110.018
cardiac muscle cell contractionGO:008600340.018
compound eye developmentGO:004874910.018
inner ear morphogenesisGO:004247240.018
positive regulation of cellular component movementGO:00512721810.018
associative learningGO:000830610.018
neurological system processGO:00508771630.018
positive regulation of protein kinase activityGO:00458601900.018
regulation of immune responseGO:00507762010.018
peripheral nervous system developmentGO:000742220.017
negative regulation of transportGO:00510511760.017
regulation of secretionGO:00510461940.017
response to cytokineGO:00340972320.017
modification dependent protein catabolic processGO:00199412090.017
growthGO:00400072020.017
cell activationGO:00017752130.017
release of cytoplasmic sequestered nf kappabGO:000858840.017
negative regulation of transcription from rna polymerase ii promoterGO:00001222810.017
neural tube formationGO:000184130.017
protein targetingGO:00066051870.017
regulation of protein catabolic processGO:00421761550.017
positive regulation of cell differentiationGO:00455972110.017
negative regulation of intracellular signal transductionGO:19025321830.017
positive regulation of locomotionGO:00400171860.017
regulation of synaptic plasticityGO:004816730.017
positive regulation of mapk cascadeGO:00434101900.017
spermatid differentiationGO:004851540.017
reactive oxygen species biosynthetic processGO:190340940.017
maintenance of locationGO:00512351120.017
regulation of wnt signaling pathwayGO:00301111230.017
positive regulation of kinase activityGO:00336742040.017
cation homeostasisGO:00550801890.017
cellular homeostasisGO:00197251960.017
cellular protein complex assemblyGO:00436231880.017
Worm
regulation of small gtpase mediated signal transductionGO:00510561560.017
monocarboxylic acid metabolic processGO:00327871850.017
actin cytoskeleton organizationGO:00300362070.017
Worm
circadian behaviorGO:004851220.017
histone modificationGO:00165702510.016
glycoprotein metabolic processGO:00091001100.016
neuroblast proliferationGO:000740540.016
covalent chromatin modificationGO:00165692540.016
protein oligomerizationGO:00512591730.016
positive regulation of cytokine productionGO:00018191670.016
negative regulation of developmental processGO:00510932470.016
regulation of cell adhesionGO:00301551660.016
chromatin modificationGO:00165682980.016
response to lipidGO:00339932060.016
reactive nitrogen species metabolic processGO:200105730.016
morphogenesis of a polarized epitheliumGO:000173830.016
actin filament based movementGO:0030048170.016
neurotransmitter secretionGO:000726940.016
limbic system developmentGO:002176130.016
photoreceptor cell differentiationGO:004653020.016
anterior posterior axis specification embryoGO:000859520.016
nitrogen compound transportGO:00717051910.016
positive regulation of cell migrationGO:00303351720.016
organophosphate biosynthetic processGO:00904071630.016
neurogenesisGO:00220081690.016
ribonucleoside monophosphate metabolic processGO:00091611870.016
purine ribonucleoside monophosphate metabolic processGO:00091671860.016
lipid biosynthetic processGO:00086101770.016
protein localization to membraneGO:00726571600.016
cell fate determinationGO:000170930.016
tripartite regional subdivisionGO:000735120.016
organelle assemblyGO:00709251760.016
Worm
spermatid developmentGO:000728640.016
blood vessel morphogenesisGO:00485141620.016
cell cycle phase transitionGO:00447701730.016
salivary gland morphogenesisGO:000743540.016
positive regulation of synaptic transmissionGO:005080640.016
positive regulation of organelle organizationGO:00106381950.016
regulation of secretion by cellGO:19035301770.016
positive regulation of cellular component biogenesisGO:00440891580.016
epithelial cell differentiationGO:00308551410.016
blood vessel developmentGO:00015681720.016
response to growth factorGO:00708482050.016
atp metabolic processGO:00460341760.015
reactive oxygen species metabolic processGO:0072593750.015
proteasomal protein catabolic processGO:00104981760.015
positive regulation of cell motilityGO:20001471770.015
syncytium formation by plasma membrane fusionGO:000076820.015
nerve developmentGO:002167540.015
purine nucleoside monophosphate metabolic processGO:00091261860.015
negative regulation of cell cycleGO:00457861930.015
regulation of peptidase activityGO:00525471800.015
cellular response to growth factor stimulusGO:00713631970.015
negative regulation of phosphorylationGO:00423261740.015
tissue regenerationGO:004224630.015
cell divisionGO:00513011680.015
regulation of reactive oxygen species biosynthetic processGO:190342630.015
nucleoside monophosphate metabolic processGO:00091231910.015
metencephalon developmentGO:002203720.015
cell growthGO:00160491600.015
regulation of ras gtpase activityGO:00323181280.015
vasculature developmentGO:00019441810.015
peptidyl tyrosine modificationGO:00182121700.015
cellular chemical homeostasisGO:00550821800.015
hemopoiesisGO:00300971800.015
actin mediated cell contractionGO:0070252120.015
angiogenesisGO:00015251470.015
response to organic cyclic compoundGO:00140702040.014
regulation of protein maturationGO:19033171500.014
regulation of mitotic cell cycleGO:00073461890.014
regulation of vesicle mediated transportGO:00606271300.014
Worm
metal ion homeostasisGO:00550651690.014
canonical wnt signaling pathwayGO:00600701160.014
posttranscriptional regulation of gene expressionGO:00106082130.014
regulation of endopeptidase activityGO:00525481700.014
nuclear transportGO:00511691790.014
cell substrate adhesionGO:00315891320.014
nucleocytoplasmic transportGO:00069131760.014
immune system developmentGO:00025201950.014
regulation of neural precursor cell proliferationGO:200017740.014
generation of neuronsGO:00486991520.014
positive regulation of protein transportGO:00512221350.014
positive regulation of immune responseGO:00507781590.014
response to axon injuryGO:004867810.014
cell projection assemblyGO:00300311260.014
negative regulation of organelle organizationGO:00106391260.014
cellular cation homeostasisGO:00300031630.014
regulation of multi organism processGO:00439001570.014
rna interferenceGO:001624640.014
peptidyl tyrosine phosphorylationGO:00181081700.014
regulation of cell morphogenesisGO:00226041530.014
negative regulation of protein processingGO:00109551420.014
i kappab kinase nf kappab signalingGO:00072491660.014
regulation of dna metabolic processGO:00510521530.014
single organismal cell cell adhesionGO:00163371480.014
regulation of protein complex assemblyGO:00432541470.014
establishment of protein localization to organelleGO:00725941720.014
organic acid biosynthetic processGO:0016053970.014
myoblast fusionGO:000752010.014
cellular response to cytokine stimulusGO:00713451810.014
regulation of cell developmentGO:00602841610.014
interspecies interaction between organismsGO:00444191560.014
immune effector processGO:00022521590.014
regulation of protein processingGO:00706131500.014
positive regulation of proteolysisGO:00458621420.014
establishment of planar polarityGO:000173630.013
cell part morphogenesisGO:00329901370.013
visual behaviorGO:000763220.013
hematopoietic or lymphoid organ developmentGO:00485341860.013
primary neural tube formationGO:001402030.013
divalent metal ion transportGO:00708381520.013
cell projection morphogenesisGO:00488581290.013
carboxylic acid biosynthetic processGO:0046394970.013
multi organism cellular processGO:00447641560.013
sex determinationGO:000753030.013
response to woundingGO:00096111680.013
microtubule cytoskeleton organizationGO:00002261760.013
regulation of cytoplasmic transportGO:19036491490.013
rna processingGO:00063962550.013
regulation of meiotic cell cycleGO:005144540.013
epithelium migrationGO:00901321190.013
actin filament organizationGO:00070151280.013
negative regulation of protein maturationGO:19033181420.013
stem cell divisionGO:001714520.013
positive regulation of ras gtpase activityGO:00323201170.013
response to fungusGO:000962040.013
long term memoryGO:000761620.013
matingGO:000761810.013
plasma membrane organizationGO:00070091150.013
sequestering of metal ionGO:0051238240.013
regulation of neurotransmitter secretionGO:004692830.013
regulation of growthGO:00400081650.013
epithelial cell migrationGO:00106311190.013
cellular metal ion homeostasisGO:00068751460.013
establishment of protein localization to membraneGO:00901501210.013
endocytosisGO:00068971590.013
Worm
leukocyte activationGO:00453211640.013
regulation of actin filament based processGO:00329701410.013
endosomal transportGO:00161971290.013
specification of organ identityGO:001009230.013
proteasome mediated ubiquitin dependent protein catabolic processGO:00431611560.013
nucleoside monophosphate catabolic processGO:00091251590.013
tissue migrationGO:00901301190.013
regulation of protein serine threonine kinase activityGO:00719001790.013
divalent inorganic cation transportGO:00725111580.013
cerebellum developmentGO:002154920.013
spinal cord developmentGO:002151040.013
lung alveolus developmentGO:004828640.013
mitotic cell cycle phase transitionGO:00447721620.013
positive regulation of reactive oxygen species biosynthetic processGO:190342820.013
epidermis morphogenesisGO:004873030.013
forebrain generation of neuronsGO:002187230.013
pituitary gland developmentGO:002198320.013
monovalent inorganic cation transportGO:00156721280.013
tube closureGO:006060630.013
g protein coupled receptor signaling pathwayGO:00071862070.013
regulation of i kappab kinase nf kappab signalingGO:00431221620.012
response to nitrogen compoundGO:19016981840.012
negative regulation of cell differentiationGO:00455961710.012
negative regulation of proteolysisGO:00458611320.012
epithelial cell proliferationGO:00506731280.012
taxisGO:00423301570.012
sequestering of calcium ionGO:0051208170.012
establishment of tissue polarityGO:000716430.012
positive regulation of gliogenesisGO:001401540.012
somitogenesisGO:000175620.012
muscle system processGO:0003012810.012
symbiosis encompassing mutualism through parasitismGO:00444031560.012
calcium ion transportGO:00068161470.012
t cell differentiation in thymusGO:003307740.012
regulation of defense responseGO:00313471540.012
regulation of cell growthGO:00015581350.012
cellular ion homeostasisGO:00068731680.012
negative regulation of protein phosphorylationGO:00019331400.012
regulation of dephosphorylationGO:0035303960.012
chemotaxisGO:00069351570.012
regulation of ion transportGO:00432691890.012
activation of immune responseGO:00022531140.012
regulation of apoptotic signaling pathwayGO:20012331750.012
mitochondrion organizationGO:00070051560.012
establishment or maintenance of bipolar cell polarityGO:006124520.012
organ morphogenesisGO:00098871470.012
organic hydroxy compound metabolic processGO:19016151470.012
divalent inorganic cation homeostasisGO:00725071360.012
atp catabolic processGO:00062001570.012
purine ribonucleoside monophosphate catabolic processGO:00091691580.012
positive regulation of i kappab kinase nf kappab signalingGO:00431231320.012
sensory perception of painGO:001923340.012
somatic stem cell divisionGO:004810310.012
neuron projection regenerationGO:003110210.012
post embryonic organ developmentGO:004856910.012
negative regulation of locomotionGO:00400131180.012
positive regulation of secretionGO:00510471160.012
neuron differentiationGO:00301821380.012
ameboidal type cell migrationGO:00016671350.012
positive regulation of sequence specific dna binding transcription factor activityGO:00510911310.012
cellular response to lipidGO:00713961270.012
sensory perception of smellGO:000760820.012
protein autophosphorylationGO:00467771230.012
protein localization to nucleusGO:00345041360.012
neuron developmentGO:00486661130.012
negative regulation of cell migrationGO:00303361020.012
ribonucleoside monophosphate catabolic processGO:00091581580.012
glycoprotein biosynthetic processGO:0009101910.012
regulation of canonical wnt signaling pathwayGO:0060828880.012
oligosaccharide biosynthetic processGO:000931230.012
fatty acid metabolic processGO:00066311150.011
response to radiationGO:00093141510.011
startle responseGO:000196430.011
response to virusGO:00096151260.011
midgut developmentGO:000749410.011
alcohol metabolic processGO:00060661140.011
regulation of intracellular protein transportGO:00331571230.011
response to bacteriumGO:00096171440.011
positive regulation of neural precursor cell proliferationGO:200017920.011
positive regulation of secretion by cellGO:19035321080.011
protein acylationGO:00435431380.011
thymus developmentGO:004853830.011
striated muscle contractionGO:0006941520.011
negative regulation of wnt signaling pathwayGO:0030178690.011
organic anion transportGO:00157111030.011
central nervous system developmentGO:00074171230.011
regulation of transcription from rna polymerase ii promoter mitoticGO:004602110.011
somatic stem cell maintenanceGO:003501940.011
response to hormoneGO:00097251750.011
developmental programmed cell deathGO:001062330.011
regulation of membrane potentialGO:0042391950.011
visual learningGO:000854210.011
regulation of cell cycle phase transitionGO:19019871260.011
cell morphogenesis involved in differentiationGO:00009041440.011
neural crest cell developmentGO:001403230.011
meiosis iGO:000712740.011
somatic muscle developmentGO:000752510.011
sulfur compound metabolic processGO:00067901010.011
positive regulation of reactive oxygen species metabolic processGO:2000379240.011
negative regulation of cell cycle processGO:00109481210.011
meiotic chromosome segregationGO:004513240.011

PLEKHG1 disease predictions

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of metabolismDOID:00146672950.030
sensory system diseaseDOID:00501552030.027
nervous system diseaseDOID:8634310.027
musculoskeletal system diseaseDOID:172230.026
inherited metabolic disorderDOID:6552420.022
central nervous system diseaseDOID:3311860.020
cancerDOID:1621670.020
disease of cellular proliferationDOID:145661740.020
organ system cancerDOID:00506861640.020
eye and adnexa diseaseDOID:14921500.019
eye diseaseDOID:56141490.019
immune system diseaseDOID:29141550.017
connective tissue diseaseDOID:651090.016
retinal diseaseDOID:56791180.015
bone diseaseDOID:0080001880.015
muscle tissue diseaseDOID:661130.015
muscular diseaseDOID:00800001140.015
cardiovascular system diseaseDOID:12871060.014
neurodegenerative diseaseDOID:12891020.014
myopathyDOID:4231040.014
retinal degenerationDOID:8466890.012
hematopoietic system diseaseDOID:741000.012
brain diseaseDOID:936730.012