Homo sapiens

30 known processes

CCM2

cerebral cavernous malformation 2

(Aliases: MGC74868,MGC4067,OSM,C7orf22,MGC4607)

CCM2 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
regulation of cellular amine metabolic processGO:0033238110.072
amine metabolic processGO:0009308440.067
vesicle mediated transportGO:00161923710.061
cellular amino acid metabolic processGO:00065201160.059
post embryonic developmentGO:000979120.059
ribonucleoside catabolic processGO:00424544060.058
cellular amine metabolic processGO:0044106410.058
positive regulation of cellular component organizationGO:00511303760.055
ribonucleoside triphosphate catabolic processGO:00092033910.054
positive regulation of phosphorylationGO:00423273940.052
ras protein signal transductionGO:0007265730.052
regulation of cellular amino acid metabolic processGO:000652160.052
regulation of transferase activityGO:00513383550.051
nucleoside triphosphate metabolic processGO:00091414220.051
organophosphate catabolic processGO:00464344300.050
purine containing compound catabolic processGO:00725234110.049
oogenesisGO:004847720.048
female gamete generationGO:000729220.048
regulation of cellular ketone metabolic processGO:0010565500.047
negative regulation of apoptotic processGO:00430663160.046
purine nucleoside triphosphate catabolic processGO:00091463920.046
purine nucleoside triphosphate metabolic processGO:00091444120.046
glycosyl compound catabolic processGO:19016584130.045
actin filament based processGO:00300292240.045
nucleotide catabolic processGO:00091664080.045
purine nucleoside catabolic processGO:00061523980.045
cytoplasmic transportGO:00164823790.045
positive regulation of protein phosphorylationGO:00019343130.044
purine ribonucleoside metabolic processGO:00461284370.044
purine ribonucleotide catabolic processGO:00091544040.044
ribonucleotide catabolic processGO:00092614050.043
ribonucleoside triphosphate metabolic processGO:00091994120.043
regulation of cell differentiationGO:00455953930.043
oocyte differentiationGO:000999420.042
nucleoside phosphate catabolic processGO:19012924120.041
cellular ketone metabolic processGO:0042180800.041
positive regulation of cellular amino acid metabolic processGO:004576430.040
mapk cascadeGO:00001652880.040
regulation of locomotionGO:00400123290.040
cellular macromolecular complex assemblyGO:00346223240.040
negative regulation of cell deathGO:00605483450.040
purine ribonucleoside catabolic processGO:00461303980.039
purine nucleotide catabolic processGO:00061954050.039
purine ribonucleoside triphosphate catabolic processGO:00092073910.039
nucleoside triphosphate catabolic processGO:00091433940.039
positive regulation of cellular amine metabolic processGO:003324070.038
small gtpase mediated signal transductionGO:0007264780.038
negative regulation of catalytic activityGO:00430863350.037
purine ribonucleoside triphosphate metabolic processGO:00092054110.037
regulation of protein kinase activityGO:00458592890.036
regulation of cellular component movementGO:00512703340.036
nucleoside catabolic processGO:00091644080.036
regulation of kinase activityGO:00435493140.036
negative regulation of programmed cell deathGO:00430693210.036
gtp metabolic processGO:00460392390.036
positive regulation of hydrolase activityGO:00513453310.035
locomotory behaviorGO:000762610.035
membrane organizationGO:00610242920.035
negative regulation of phosphorus metabolic processGO:00105632670.035
single organism cellular localizationGO:19025803320.034
negative regulation of phosphate metabolic processGO:00459362670.033
mitotic cell cycleGO:00002783260.033
neuromuscular junction developmentGO:000752830.033
cell morphogenesisGO:00009022960.033
intracellular protein transportGO:00068862700.033
positive regulation of catabolic processGO:00098963100.033
regulation of cell cycleGO:00517263930.032
regulation of cell migrationGO:00303342890.032
regulation of mapk cascadeGO:00434082620.031
positive regulation of nucleotide metabolic processGO:00459812300.031
neuron projection regenerationGO:003110210.031
endosomal transportGO:00161971290.031
cell developmentGO:00484683280.030
Mouse
negative regulation of cellular protein metabolic processGO:00322693530.030
regulation of anatomical structure morphogenesisGO:00226032860.030
cellular macromolecule catabolic processGO:00442653800.030
oocyte developmentGO:004859910.030
positive regulation of cellular catabolic processGO:00313312840.030
regulation of cytoskeleton organizationGO:00514931770.029
regulation of protein localizationGO:00328802960.029
cellular component morphogenesisGO:00329893140.029
negative regulation of protein metabolic processGO:00512483910.029
positive regulation of purine nucleotide catabolic processGO:00331231850.028
regulation of protein serine threonine kinase activityGO:00719001790.028
regulation of cellular component biogenesisGO:00440872810.028
mitotic cell cycle processGO:19030472860.028
regulation of cell projection organizationGO:00313441070.027
regenerationGO:003109940.027
positive regulation of transferase activityGO:00513472270.027
determination of adult lifespanGO:000834020.026
positive regulation of immune system processGO:00026842830.026
protein catabolic processGO:00301633250.026
response to oxygen containing compoundGO:19017003690.026
multicellular organismal agingGO:001025930.026
biological adhesionGO:00226103310.026
regulation of response to external stimulusGO:00321012220.026
regulation of purine nucleotide catabolic processGO:00331212050.026
protein localization to organelleGO:00333652800.026
gtp catabolic processGO:00061842370.025
regulation of cellular response to stressGO:00801352440.025
regulation of purine nucleotide metabolic processGO:19005422640.025
organonitrogen compound biosynthetic processGO:19015662000.025
system processGO:00030083490.025
regulation of cell cycle processGO:00105642660.025
single organism membrane organizationGO:00448022680.025
transmembrane transportGO:00550853990.025
positive regulation of transportGO:00510503360.025
regulation of nucleotide metabolic processGO:00061402690.024
regulation of cell motilityGO:20001452990.024
cell projection organizationGO:00300302520.024
regulation of nucleoside metabolic processGO:00091182090.024
positive regulation of cell proliferationGO:00082843010.024
cell adhesionGO:00071553250.023
response to abiotic stimulusGO:00096283360.023
positive regulation of purine nucleotide metabolic processGO:19005442270.023
apoptotic signaling pathwayGO:00971902680.023
signal transduction by phosphorylationGO:00230142970.023
rho protein signal transductionGO:0007266260.023
actin cytoskeleton organizationGO:00300362070.023
blood vessel developmentGO:00015681720.023
regulation of intracellular transportGO:00323861950.022
positive regulation of protein kinase activityGO:00458601900.022
blood vessel morphogenesisGO:00485141620.022
regulation of nucleotide catabolic processGO:00308112050.022
negative regulation of phosphorylationGO:00423261740.022
cation transportGO:00068123310.022
carbohydrate derivative biosynthetic processGO:19011372070.022
guanosine containing compound metabolic processGO:19010682440.022
positive regulation of cellular component biogenesisGO:00440891580.022
cellular protein complex assemblyGO:00436231880.022
positive regulation of developmental processGO:00510943140.022
adult locomotory behaviorGO:000834410.022
negative regulation of protein modification processGO:00314002000.021
regulation of cell morphogenesisGO:00226041530.021
memoryGO:000761330.021
carbohydrate metabolic processGO:00059752070.021
response to axon injuryGO:004867810.021
nervous system developmentGO:00073992930.021
guanosine containing compound catabolic processGO:19010692390.021
positive regulation of kinase activityGO:00336742040.021
chemical homeostasisGO:00488783060.020
lipid metabolic processGO:00066293810.020
regulation of vesicle mediated transportGO:00606271300.020
purine ribonucleoside monophosphate metabolic processGO:00091671860.020
enzyme linked receptor protein signaling pathwayGO:00071673030.020
positive regulation of nucleoside metabolic processGO:00459791860.020
cellular protein catabolic processGO:00442572610.020
regulation of synaptic plasticityGO:004816730.020
associative learningGO:000830610.020
negative regulation of transferase activityGO:00513481240.020
regulation of actin filament based processGO:00329701410.020
single organism carbohydrate metabolic processGO:00447231930.020
actin filament organizationGO:00070151280.020
endomembrane system organizationGO:00102561960.020
negative regulation of multicellular organismal processGO:00512413170.019
cell divisionGO:00513011680.019
microtubule based processGO:00070172100.019
cellular response to cytokine stimulusGO:00713451810.019
protein autophosphorylationGO:00467771230.019
metal ion transportGO:00300012720.019
dephosphorylationGO:00163112090.019
regulation of map kinase activityGO:00434051080.019
nucleoside monophosphate metabolic processGO:00091231910.019
positive regulation of gtp catabolic processGO:00331261660.019
cellular response to oxygen containing compoundGO:19017012760.019
circulatory system developmentGO:00723592620.019
compound eye developmentGO:004874910.019
regulation of mitotic cell cycleGO:00073461890.019
response to cytokineGO:00340972320.019
regulation of actin cytoskeleton organizationGO:00329561160.018
defense responseGO:00069523150.018
microtubule cytoskeleton organizationGO:00002261760.018
segmentationGO:003528240.018
axon regenerationGO:003110310.018
immune responseGO:00069553070.018
cellular lipid metabolic processGO:00442553030.018
regulation of cell developmentGO:00602841610.018
negative regulation of cellular amino acid metabolic processGO:004576320.018
ion homeostasisGO:00508012300.017
positive regulation of protein serine threonine kinase activityGO:00719021190.017
regulation of protein complex assemblyGO:00432541470.017
negative regulation of cellular amine metabolic processGO:003323930.017
peptidyl tyrosine modificationGO:00182121700.017
maintenance of locationGO:00512351120.017
ion transmembrane transportGO:00342203380.017
nuclear transportGO:00511691790.017
cell projection morphogenesisGO:00488581290.017
ribonucleoside monophosphate metabolic processGO:00091611870.017
neurotransmitter secretionGO:000726940.017
regulation of growthGO:00400081650.017
neuron developmentGO:00486661130.017
secretion by cellGO:00329402260.017
blastoderm segmentationGO:000735020.017
organelle localizationGO:0051640840.017
protein targetingGO:00066051870.017
positive regulation of gtpase activityGO:00435471660.017
cellular response to endogenous stimulusGO:00714953360.017
positive regulation of cell differentiationGO:00455972110.016
neurogenesisGO:00220081690.016
chromatin organizationGO:00063253510.016
negative regulation of cellular component organizationGO:00511292350.016
negative regulation of cell cycleGO:00457861930.016
protein ubiquitinationGO:00165673140.016
cell projection assemblyGO:00300311260.016
purine nucleoside monophosphate metabolic processGO:00091261860.016
positive regulation of synaptic transmissionGO:005080640.016
positive regulation of mapk cascadeGO:00434101900.016
protein maturationGO:00516042330.016
protein localization to membraneGO:00726571600.016
positive regulation of nucleotide catabolic processGO:00308131850.016
regulation of small gtpase mediated signal transductionGO:00510561560.016
regulation of ion transportGO:00432691890.016
regulation of gtpase activityGO:00430871800.016
regulation of gtp catabolic processGO:00331241800.016
proteolysis involved in cellular protein catabolic processGO:00516032440.016
negative regulation of protein phosphorylationGO:00019331400.016
regulation of proteolysisGO:00301622930.016
organophosphate biosynthetic processGO:00904071630.016
spermatid differentiationGO:004851540.016
regulation of establishment of protein localizationGO:00702012420.015
neuron differentiationGO:00301821380.015
negative regulation of hydrolase activityGO:00513461820.015
protein modification by small protein conjugationGO:00324463420.015
positive regulation of locomotionGO:00400171860.015
spermatid developmentGO:000728640.015
positive regulation of cell deathGO:00109422630.015
hindbrain developmentGO:003090230.015
cell cycle phase transitionGO:00447701730.015
growthGO:00400072020.015
Mouse
atp metabolic processGO:00460341760.015
inorganic cation transmembrane transportGO:00986621940.015
response to growth factorGO:00708482050.015
neurological system processGO:00508771630.015
rna processingGO:00063962550.015
morphogenesis of embryonic epitheliumGO:001633140.015
regulation of multi organism processGO:00439001570.015
cardiovascular system developmentGO:00723582620.015
modification dependent macromolecule catabolic processGO:00436322120.015
regulation of anatomical structure sizeGO:00900661010.015
cell activationGO:00017752130.015
cellular response to dna damage stimulusGO:00069743790.015
synaptic vesicle endocytosisGO:004848820.015
cell growthGO:00160491600.015
cellular homeostasisGO:00197251960.015
vasculature developmentGO:00019441810.015
cellular chemical homeostasisGO:00550821800.015
regulation of protein transportGO:00512232130.015
positive regulation of cellular component movementGO:00512721810.015
synaptic vesicle recyclingGO:003646530.015
generation of neuronsGO:00486991520.014
positive regulation of ras gtpase activityGO:00323201170.014
negative regulation of locomotionGO:00400131180.014
vesicle organizationGO:0016050620.014
nucleocytoplasmic transportGO:00069131760.014
negative regulation of transportGO:00510511760.014
calcium ion transportGO:00068161470.014
modification dependent protein catabolic processGO:00199412090.014
cation homeostasisGO:00550801890.014
purine nucleoside monophosphate catabolic processGO:00091281580.014
g protein coupled receptor signaling pathwayGO:00071862070.014
mitotic nuclear divisionGO:00070671190.014
cell part morphogenesisGO:00329901370.014
ribonucleoside monophosphate catabolic processGO:00091581580.014
positive regulation of cell migrationGO:00303351720.014
anatomical structure formation involved in morphogenesisGO:00486462840.014
divalent metal ion transportGO:00708381520.014
rhythmic behaviorGO:000762220.014
response to fungusGO:000962040.014
regulation of ras gtpase activityGO:00323181280.014
epithelium developmentGO:00604292270.014
establishment of protein localization to organelleGO:00725941720.014
nucleus localizationGO:005164710.014
ubiquitin dependent protein catabolic processGO:00065112060.014
transmembrane receptor protein tyrosine kinase signaling pathwayGO:00071691810.014
cellular cation homeostasisGO:00300031630.014
response to external biotic stimulusGO:00432072610.014
regulation of ras protein signal transductionGO:00465781550.014
negative regulation of cell motilityGO:20001461040.013
positive regulation of organelle organizationGO:00106381950.013
cell cell signalingGO:00072671550.013
protein processingGO:00164852260.013
negative regulation of cell migrationGO:00303361020.013
peripheral nervous system developmentGO:000742220.013
mitotic cell cycle phase transitionGO:00447721620.013
dna repairGO:00062811980.013
metal ion homeostasisGO:00550651690.013
innate immune responseGO:00450871780.013
response to radiationGO:00093141510.013
negative regulation of cell proliferationGO:00082852280.013
chromatin modificationGO:00165682980.013
oxidation reduction processGO:00551143960.013
secretionGO:00469032540.013
anterior posterior axis specification embryoGO:000859520.013
cation transmembrane transportGO:00986552380.013
protein oligomerizationGO:00512591730.013
atp catabolic processGO:00062001570.013
regulation of cytoplasmic transportGO:19036491490.013
positive regulation of apoptotic processGO:00430652460.013
organ morphogenesisGO:00098871470.013
multi organism cellular processGO:00447641560.013
somatic muscle developmentGO:000752510.013
positive regulation of programmed cell deathGO:00430682490.013
alcohol metabolic processGO:00060661140.013
negative regulation of intracellular signal transductionGO:19025321830.013
peptidyl tyrosine phosphorylationGO:00181081700.013
intrinsic apoptotic signaling pathwayGO:00971931270.012
positive regulation of map kinase activityGO:0043406800.012
regulation of protein catabolic processGO:00421761550.012
regulation of secretion by cellGO:19035301770.012
regulation of immune responseGO:00507762010.012
cellular metal ion homeostasisGO:00068751460.012
cell type specific apoptotic processGO:00972851250.012
inorganic ion transmembrane transportGO:00986602310.012
negative regulation of protein kinase activityGO:0006469980.012
visual behaviorGO:000763220.012
purine ribonucleoside monophosphate catabolic processGO:00091691580.012
establishment of nucleus localizationGO:004002310.012
embryonic epithelial tube formationGO:000183840.012
regulation of intracellular protein transportGO:00331571230.012
regulation of response to woundingGO:19030341010.012
endocytosisGO:00068971590.012
small molecule biosynthetic processGO:00442831570.012
proteasomal protein catabolic processGO:00104981760.012
epithelial cell migrationGO:00106311190.012
reactive oxygen species metabolic processGO:0072593750.012
syncytium formation by plasma membrane fusionGO:000076820.012
negative regulation of organelle organizationGO:00106391260.012
positive regulation of cell motilityGO:20001471770.012
histone modificationGO:00165702510.012
cellular response to growth factor stimulusGO:00713631970.012
organelle assemblyGO:00709251760.012
negative regulation of cellular component movementGO:00512711060.012
regulation of metal ion transportGO:00109591200.012
lipid biosynthetic processGO:00086101770.012
visual learningGO:000854210.012
reproductive processGO:00224141060.012
hemopoiesisGO:00300971800.012
symbiosis encompassing mutualism through parasitismGO:00444031560.012
neuroblast proliferationGO:000740540.012
inner ear morphogenesisGO:004247240.012
establishment of organelle localizationGO:0051656590.012
cell morphogenesis involved in differentiationGO:00009041440.012
golgi vesicle transportGO:0048193800.012
nitrogen compound transportGO:00717051910.012
reactive oxygen species biosynthetic processGO:190340940.012
response to other organismGO:00517072610.012
motor neuron axon guidanceGO:000804520.011
anterior posterior axis specificationGO:000994820.011
divalent inorganic cation transportGO:00725111580.011
covalent chromatin modificationGO:00165692540.011
regulation of secretionGO:00510461940.011
negative regulation of kinase activityGO:00336731060.011
cell junction organizationGO:0034330790.011
Mouse
response to woundingGO:00096111680.011
immune system developmentGO:00025201950.011
metencephalon developmentGO:002203720.011
positive regulation of cell developmentGO:0010720920.011
regulation of nervous system developmentGO:0051960880.011
organic hydroxy compound metabolic processGO:19016151470.011
actin mediated cell contractionGO:0070252120.011
nucleoside monophosphate catabolic processGO:00091251590.011
regulation of homeostatic processGO:00328441210.011
response to oxidative stressGO:00069791210.011
regulation of neural precursor cell proliferationGO:200017740.011
peptidyl serine modificationGO:00182091060.011
regulation of cell cycle phase transitionGO:19019871260.011
regulation of cell growthGO:00015581350.011
circadian behaviorGO:004851220.011
response to biotic stimulusGO:00096072760.011
regulation of cell morphogenesis involved in differentiationGO:0010769830.011
epithelial cell differentiationGO:00308551410.011
Mouse
myoblast fusionGO:000752010.011
single organism cell adhesionGO:00986021790.011
lymphocyte homeostasisGO:000226040.011
protein localization to nucleusGO:00345041360.011
regulation of protein processingGO:00706131500.011
nuclear divisionGO:00002801280.011
organelle fissionGO:00482851490.011
interspecies interaction between organismsGO:00444191560.011
positive regulation of cell projection organizationGO:0031346640.011
regulation of cytokine productionGO:00018172320.011
cellular ion homeostasisGO:00068731680.011
negative regulation of immune system processGO:00026831360.011
cardiac muscle cell contractionGO:008600340.011
ameboidal type cell migrationGO:00016671350.011
establishment of protein localization to membraneGO:00901501210.011
immune effector processGO:00022521590.011
head developmentGO:00603221080.011
nucleoside phosphate biosynthetic processGO:19012931090.011
positive regulation of proteolysisGO:00458621420.011
nuclear migrationGO:000709710.011
rna splicingGO:00083801310.011
neuron projection developmentGO:00311751060.011
regulation of mitotic cell cycle phase transitionGO:19019901180.011
nerve developmentGO:002167540.010
regulation of reactive oxygen species biosynthetic processGO:190342630.010
cell substrate adhesionGO:00315891320.010
protein acylationGO:00435431380.010
response to lipidGO:00339932060.010
regulation of dephosphorylationGO:0035303960.010
cell fate determinationGO:000170930.010
i kappab kinase nf kappab signalingGO:00072491660.010
tube closureGO:006060630.010
anion transportGO:00068201610.010
regulation of dna metabolic processGO:00510521530.010
hematopoietic or lymphoid organ developmentGO:00485341860.010
regulation of endopeptidase activityGO:00525481700.010
regulation of apoptotic signaling pathwayGO:20012331750.010
sensory perception of painGO:001923340.010
regulation of cellular component sizeGO:0032535820.010
regulation of neuron projection regenerationGO:007057010.010
tripartite regional subdivisionGO:000735120.010
carboxylic acid biosynthetic processGO:0046394970.010
reactive nitrogen species metabolic processGO:200105730.010
t cell differentiation in thymusGO:003307740.010
posttranscriptional regulation of gene expressionGO:00106082130.010
proteasome mediated ubiquitin dependent protein catabolic processGO:00431611560.010
regulation of cell adhesionGO:00301551660.010
negative regulation of protein processingGO:00109551420.010
regulation of transmembrane transportGO:00347621390.010
regulation of sequence specific dna binding transcription factor activityGO:00510902110.010
glycoprotein metabolic processGO:00091001100.010
regulation of oocyte developmentGO:006028110.010
regulation of transporter activityGO:0032409820.010
sequestering of metal ionGO:0051238240.010

CCM2 disease predictions

DiseaseDO term IDSizeProbabilityFunc Analog Org
nervous system diseaseDOID:8634310.023
central nervous system diseaseDOID:3311860.023
disease of metabolismDOID:00146672950.021
musculoskeletal system diseaseDOID:172230.018
disease of cellular proliferationDOID:145661740.016
sensory system diseaseDOID:00501552030.015
eye and adnexa diseaseDOID:14921500.015
eye diseaseDOID:56141490.015
organ system cancerDOID:00506861640.014
cancerDOID:1621670.014
immune system diseaseDOID:29141550.014
neurodegenerative diseaseDOID:12891020.013
inherited metabolic disorderDOID:6552420.012
connective tissue diseaseDOID:651090.012
bone diseaseDOID:0080001880.011
brain diseaseDOID:936730.011
retinal diseaseDOID:56791180.011